9th Annual Conference of the Association of Physiologists of Tamil Nadu (APTCON - 2015)
APTCON 2015 - “CORPHYSIOCON”
ASSOCIATION BETWEEN DIABETIC RETINOPATHY AND DURATION OF DIABETES IN TYPE 2 DIABETICS
Koushiki Mani, Rose Davy.C
Department of Physiology, Government T D Medical College, Alappuzha
Introduction
Results
Discussion
 Diabetic retinopathy is a well-known complication of diabetes
mellitus.
 Due to long term hyperglycemia, damage to microvasculature
of retina occurs leading to diabetic retinopathy.
 Duration of diabetes is one of the major risk factors of
diabetic retinopathy.¹
 Out of 200 subjects, 63 subjects (31.5%) affected with
Diabetic retinopathy.( Non-proliferative retinopathy=22.5% ,
Proliferative retinopathy= 9%)
 Prevalence of diabetic retinopathy with duration of diabetes
more than 25 years was 85% .
7,50%
STAGES OF DIABETIC
RETINOPATHY
7,50%
7,50%
NO DR
9%
MILD NPDR
Aims and objectives
68,50%
MODERATE NPDR
 Study design-cross-sectional
 Study Sample -200 already diagnosed type 2 diabetic
subjects.
 Exclusion criteria-Subjects with hazy media or any
other eye disease.
 Data regarding age, sex, age at onset of diabetes,
duration of diabetes was collected.
 Then they were evaluated for diabetic retinopathy by
fundus examination.
 Findings were noted and subjects were categorized as
no
retinopathy,
non-proliferative(NPDR)
and
proliferative diabetic retinopathy(PDR)
 Thus, with increasing duration of diabetes, the severity of
diabetic retinopathy increases.²
SEVERE NPDR
 To study the association between duration of diabetes and
diabetic retinopathy in type 2 diabetic patients attending a
government hospital in Kerala.
Materials and methods
 Prevalence of
Proliferative diabetic retinopathy was
higher with duration of diabetes more than 25 years.
Conclusion
PDR
NO. OF
DURATION OF
MILD NPDR
PATIENT
DM( YRS)
%
S.
MODERATE
NPDR
%
SEVERE
NPDR
%
PDR
%
1-5
52
0%(0)
0%(0)
0%(0)
1.9%(1)
6-10
38
13.2%(5)
2.6%(1)
0%(0)
2.6%(1)
11-15
24
16.7%(4)
12.5%(3)
4.2%(1)
8.3%(2)
P VALUE(* )
 Periodic screening of diabetic patients will help in
early detection and hence prevent loss of vision.
< 0.05
16-20
36
8.3%(3)
13.9%(5)
8.3%(3)
8.3%(3)
21-25
26
11.5%(3)
15.4%(4)
15.4%(4)
11.5%(3)
> 25
24
0%(0)
8.3%(2)
29.2%(7)
33.3%(8)
•Result 1
•Result 2
 Binary logistic regression analysis showed an independent association
•Result 3
*Pearson Chi-square test
between duration of diabetes and diabetic retinopathy (p<0.05).
 Accurate data regarding the type and severity of
diabetic retinopathy is important in assessing the
burden on public health system.
References
1. Leske MC, Wu SY, Nemesure B, Hennis A. Barbados Eye
Studies Group. Causes of visual loss and their risk factors: An
incidence summary from the Barbados Eye Studies. Rev Panam
Salud Publica. 2010;27:259–67.
2. Ramavat,Piyush;Rameshchandran;Ramavat,Manish,Rameshcha
ndran;Ghugare,Balaji Wasudeo;Vaishnav Rohini
G;Joshi,Manjari Uttam; Prevalence of Diabetic Retinopathy in
Western Indian Type 2 diabetic population: A Hospital-based
cross-sectional study, Journal of clinical and diagnostic
research 2013:7-7