All the biochemical reactions in a cell is catalysed by enzymes. In many cellular reactions, such as in mitochondria the enzymes for electron transport chain are located in the membrane of the organelle. If the surface area of the membrane is large, then a greater number of enzymes can be present on this membrane. Also, enzymes are arranged in such a manner that they transfer products from one reaction to other enzyme directly inside the membrane for a second reaction, therefore the structure of the membrane is important. An example of this can be seen during cellular respiration. Within the matrix of the mitochondria are proteins (enzymes) that take molecules such as pyruvate and acetyl CoA, and chemically digest them. Proteins embedded in the inner membrane and enzymes involved in cellular respiration release water and carbon dioxide from the breakdown of glucose and oxygen. The mitochondria are the only places in the cell where oxygen is reduced and eventually broken down into water. Folding of the internal membrane facilitates the biochemical reactions that occur within the mitochondria thereby making process of ATP production for the cell more efficient.