May 18, 2016 BACKGROUND • Resuscitative endovascular balloon occlusion of the aorta (REBOA) catheter has emerged as a treatment option for critically injured patients presenting with imminent cardiac arrest due to hemorrhagic shock BACKGROUND • This balloon occlusion of the thoracic aorta can theoretically mitigate downstream blood loss while facilitating coronary and brain perfusion BACKGROUND • Placement under fluoroscopic guidance • Postplacement x-ray for confirmation of balloon location after blind insertion BACKGROUND • Surface measurements may allow individualized estimation of the intravascular distance for safe balloon deployment • The initial placement is important as overinsertion risks cerebral ischemia, whereas not advancing far enough will potentially decrease the efficacy of haemorrhage control BACKGROUND • To date, no human surface landmark-guided placement studies have been performed • We used a human cadaver model to determine which external surface landmark was most reliable for guiding the blind insertion of the REBOA catheter METHODS • A convenience sample of cadavers at the Los Angeles County-University of Southern California Fresh Tissue Dissection Laboratory were included in the study • July 2013 to June 2014 METHODS • Age, sex, height, weight, and body mass index (BMI) were documented • Any cadaver with previous femoral vascular instrumentation or thoracotomy or laparotomy was excluded METHODS • Standard Cook CODA balloon catheter • The catheter is 120 cm long, whereas the balloon itself is 4 cm long, with the distal balloon edge located 2 cm from the tip of the catheter METHODS • External surface measurements • Sternal notch • Xiphoid • Umbilicus • Common femoral artery puncture sites • External distances measured were from sternal notch, xiphoid, and umbilicus to bilateral puncture sites METHODS • Intravascular measurements • Distance from common femoral artery puncture sites to the aortic bifurcation, most inferior renal artery, superior mesenteric artery, celiac trunk and left subclavian artery take off METHODS • REBOA landing zone was defined as the area between the left subclavian artery take off and celiac trunk RESULTS DISCUSSION • First human cadaver–based study • Reliable method of REBOA catheter placement without the use of fluoroscopic guidance • Using direct measurement of external landmarks • As the aim of REBOA placement was to decrease blood loss from any injuries below the diaphragm, aortic Zone 1 was the target DISCUSSION • Our study had several limitations • Mean age of cadavers was higher than that of typical trauma patient • Changes in aortic morphology over time may alter how these results are translated into a younger patient • BMI was consistently low • Obesity may artificially lengthen the estimated distance CONCLUSION • Using the mid-sternum as an external landmark for REBOA balloon placement • Likelihood of the REBOA balloon to be within the landing zone is 100% • This may facilitate emergent placement of the REBOA catheter when imaging is not available • Further clinical studies are warranted to apply the results of this study in the clinical setting