SHIFTING FIBER TYPE I II b O2 Glikogen Glukosa 2 piruvat+2NADH O2 GLIKOLISIS 2NADH 2 ATP O2 Laktat Asetil Ko-A KREBS CYCLE 6NADH 2FADH CO2 Kirkham PA, Barnes PJ. Oxidative stress in COPD. Chest [Internet]. 2013;144(1):266–73. Available from: http://dx.doi.org/10.1378/chest.12 10 NADH 2 FADH 2 ATP Kirkham PA, Barnes PJ. Oxidative stress in COPD. Chest [Internet]. 2013;144(1):266–73. Available from: http://dx.doi.org/10.1378/chest.12-2664 O2 + 3e- = OH O2- SOD H+ H+ 2e- 2e- NADH + H+ NAD O2 2e- H+ H+ H+ H+ Sitokrom C Sitokrom C 2e- H+ H+ H+ H+ Q QH2+2e QH2 H+ H+ H+ H+ H + H+ H+ H+ H+ H+ H+ H+ Fe, Cu 2e- FADH2 + H+ FAD O2 + 2H+ ½ O2 + 2H+ H2O2 H2O2 H2O CAT ADP +Pi H+ H+ H+ H+ ATP