Common Medications Contraindications & Notes
Drug
Praxilane
(Naftidrofuryl)
Ganaton
Itopride
Trental
Pentoxifylline
Oxybral
Vincamine
Trivestal R
Piribedil
Ambeziem
Trypsin
Chymotrypsin
Procoralan
Ivabradine
Vastarel MR
Trimetazidine
Contraindications
Special Notes
1- Oxalyate Crystals
2-Recurrent Kidney Stone formation patients
Contain 38mg oxalate /
tab
1-GI Bleeding , Obstruction
Data of Long term use NOT Available
Clinical Studies :
Itopride has been
admin. Up to 8 weeks
Common Adverse
Events : 1-10%
1-GI upsets
2-Facial redness
-
1-Acute MI
2-Cerebral hemorrhagic bleeding
3-GI ulcer
4-In disease with increase bleeding Tendency
1-Convulsive Disorders
2-Cerebrovascular Accident (Acute)
3-Cardiac Arrhythmia
4- Hypokalemia , Hypocalcemia
1- Myocardial infarction
2- Serious Cardiovascular disease
3- With Antiemetic Neuroleptics
1-Severe General & Local Infection
2- Peptic Ulcer
3-Severe Hepatic Or Renal disease
4- Disorder in blood clotting mechanism
( Hemorrhagic Diathesis )
1-HR < 70 b/m
2-Cardiogenic shock OR ( Acute HF)
3-Rhysm Disorder
4-Very Low blood Pressure
5-Heart attack
6-Unstable Angina (with very frequently chest pain
7-Severe liver Problem
1-Parkinson Disease
2-Severe Kidney Problem
References: Package Leaflet of Manufactures
May induce QT
prolongation , TDP
Indicated Use of
Trivestal is for ttt of
Parkinson Disease
( Dopamine Agonist)
Avoid use with
Anticoagulants
Procoralan is
1-CYP 3A4 Substrate
2-May Induce Risk of QT
Very Common
Adverse Event : >10%
Luminous Visual
(Brightness)