Cigarettes and your DNA 1. Every year, smoking causes how many deaths in the United States? _________________ 2. List 3 health problems related to smoking. _____________________, ______________________, and _______________________. 3. How many types of cancer are related to smoking cigarettes? ____________________ 4. Cigarette smoking can leave a _________ year legacy on your DNA. 5. True or False: Several changes in cells within multiple parts of the body occur from smoking a pack per day for one year. Within one year of smoking, 6. How many mutations occur in lung cells? __________________________ 7. How many mutations occur in the larynx? __________________________ 8. How many mutations occur in the oral cavity? __________________________ 9. For every year a person smokes, they accrue ______________ new mutations in their DNA. 10. Smoking causes genetic _________________________ and increases the risk of cancer. 11. Not only does smoking cause genetic mutations, but it also causes changes in one’s __________. 12. Among those who had quit smoking within five years, most of these sites were at similar levels to the ______________ _________________. 13. Smoking has an incredibly long-lasting impact on your DNA and can last _____________________ after you quit. 14. So even though the majority of your DNA methylation signals return to never-smoker levels after __________ years, your body can still struggle to heal itself decades after.