Snowman Mutations

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As snow days have become more and more common in our little town of Cass City, it is obvious that
something fishy is going on with the weather. It is likely that due to all the tractors and all the toxins that
have gone into the air, there are likely to be mutant snowflakes. Where there are mutant snowflakes, there
are mutant snowmen.
At the side of each DNA sequence, draw the snowman that results from the code. Use the codon chart to
determine the amino acid sequence and then determine the directions for each code.
Normal Snowman
1.
a.
TAC
AAA
TTA
ATG
b.
TAC
GAC
TTA
AAA
c.
TAC
TAT
TTA
GAC
d.
TAC
CAC
TTA
TAT
e.
TAC
TCG
TTA
GTA
TAT
f.
TAC
GGG
TTA
AAC
CGC
g.
TAC
TGG
TTG
TAT
ACT
__________________________________________________________________________________________
Mutant Snowmen Army
2.
a.
TAC
AAA
TTA
ATG
b.
TAC
TAT
TTA
GAC
c.
TAC
CAC
TTA
TAT
d.
TAC
TCG
TTA
GTA
TAT
e.
TAC
GGG
TTA
AAC
CGC
f.
TAC
TGG
TTG
TAT
ACT
What is the mutation type in snowman #2? Explain how you know this.
3.
a.
TAC
AAA
TTA
ATG
b.
TAC
GAC
TTA
AAA
c.
TAC
TAT
TTA
GAC
d.
TAC
CAC
TTA
TAT
e.
TAC
TCG
TTA
GTA
TAT
f.
TAC
TTT
TTA
GTA
TAT
g.
TAC
GGG
TTA
AAC
CGC
h.
TAC
TGG
TTG
TAT
ACT
What is the mutation type in snowman #3? Explain how you know this.
4.
a.
TAC
AAA
TTA
ATG
b.
TAC
GAC
TTA
AAA
c.
TAC
TAT
TTA
GAC
d.
TAC
CAC
TTA
TAT
e.
TAC
TCG
TTA
GTA
TAT
f.
TAC
TGG
TTA
AAC
CGC
g.
TAC
GGG
TTG
TAT
ACT
What is the mutation type in snowman #4?
5.
a.
TAC
AAA
TTA
ATG
b.
TAC
GAC
TTA
AAA
c.
TAC
TAT
TTA
GAC
d.
TAC
CAC
TTA
TAT
e.
TAC
TCG
TTA
GTA
TAT
f.
TAC
GGG
TTA
AAC
CGC
g.
TAC
TCG
TTG
TAT
ACT
What is the mutation type in snowman #5?
Phenylalanine =
large circle
Leucine = medium
circle
Isoleucine = small
circle
Methionine =
place
Valine = eyes
Serine = carrot
Proline = stick
Threonine = hat
Alanine = side
Tyrosine = bottom
Histidine = middle
Glutamine = top
Lysine = snake
Cysteine = puppy
Arginine = house
Tryptophan = tire
Glycine = spoon
Glutamic acid =
pumpkin
Asparagine = on
Teacher notes
Normal Snowman
●
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●
●
●
●
●
1.
Place Large Circle on Bottom
Place medium circle in middle
Place small circle on top
place eyes on small circle
place carrot middle of small circle
place sticks on middle of circle sides
place hat on small circle
a. Methionine – Phenylalanine – asparagine – tyrosine
TAC
AAA
TTA
ATG
b. methionine – leucine – asparagine – phenylalanine
TAC
GAC
TTA
AAA
c. methionine – isoleucine – asparagine – leucine
TAC
TAT
TTA
GAC
d. methionine – valine – asparagine – isoleucine
TAC
CAC
TTA
TAT
e. methionine – serine – asparagines – histadine – isoleucine
TAC
TCG
TTA
GTA
TAT
f. methionine – proline – asparagine – leucine - alanine
TAT
GGG TTA
AAC
CGC
g. methionine – threonine – asparagines - isoleucine
TAT
TGG
TTG
TAT
ACT
2. Deletion of middle circle
a. Methionine – Phenylalanine – asparagine – tyrosine
TAC
AAA
TTA
ATG
c. methionine – isoleucine – asparagine – leucine
TAC
TAT
TTA
GAC
d. methionine – valine – asparagine – isoleucine
TAC
CAC
TTA
TAT
e. methionine – serine – asparagines – histadine – isoleucine
TAC
TCG
TTA
GTA
TAT
f. methionine – proline – asparagine – leucine - alanine
TAT
GGG TTA
AAC
CGC
g. methionine – threonine – asparagines - isoleucine
TAT
TGG
TTG
TAT
ACT
3. Insertion of snake
a. Methionine – Phenylalanine – asparagine – tyrosine
TAC
AAA
TTA
ATG
b. methionine – leucine – asparagine – phenylalanine
TAC
GAC
TTA
AAA
c. methionine – isoleucine – asparagine – leucine
TAC
TAT
TTA
GAC
d. methionine – valine – asparagine – isoleucine
TAC
CAC
TTA
TAT
e. methionine – serine – asparagines – histadine – isoleucine
TAC
TCG
TTA
GTA
TAT
e. methionine – lysine – asparagines – histadine – isoleucine
TAC
TTT
TTA
GTA
TAT
f. methionine – proline – asparagine – leucine - alanine
TAT
GGG TTA
AAC
CGC
g. methionine – threonine – asparagines - isoleucine
TAT
TGG
TTG
TAT
ACT
4. Inversion sticks and hat
a. Methionine – Phenylalanine – asparagine – tyrosine
TAC
AAA
TTA
ATG
b. methionine – leucine – asparagine – phenylalanine
TAC
GAC
TTA
AAA
c. methionine – isoleucine – asparagine – leucine
TAC
TAT
TTA
GAC
d. methionine – valine – asparagine – isoleucine
TAC
CAC
TTA
TAT
e. methionine – serine – asparagines – histadine – isoleucine
TAC
TCG
TTA
GTA
TAT
f. methionine –threonine – asparagine – leucine - alanine
TAT
TGG
TTA
AAC
CGC
g. methionine – proline – asparagines - isoleucine
TAT
GGG TTG
TAT
ACT
5. Point mutation – two carrots one on face, one on top of head
a. Methionine – Phenylalanine – asparagine – tyrosine
TAC
AAA
TTA
ATG
b. methionine – leucine – asparagine – phenylalanine
TAC
GAC
TTA
AAA
c. methionine – isoleucine – asparagine – leucine
TAC
TAT
TTA
GAC
d. methionine – valine – asparagine – isoleucine
TAC
CAC
TTA
TAT
e. methionine – serine – asparagines – histadine – isoleucine
TAC
TCG
TTA
GTA
TAT
f. methionine – proline – asparagine – leucine - alanine
TAT
GGG TTA
AAC
CGC
g. methionine – Serine– asparagines - isoleucine
TAT
TCG
TTG
TAT
ACT
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