Create a Baby Lab THE HEAD OF THE COIN = THE DOMINANT FORM OF A TRAIT…THE CAPITAL LETTER *THE FIRST PART OF THE LAB, YOU HAVE TO DETERMINE THE SEX OF THE CHILD….ONLY THE PERSON REPRESENTING THE MALE FLIPS THE COIN AS THE ONE WHO REPRESENTS THE FEMALE ALREADY IS AN X. IF THIS PERSON FLIPS HEADS, THE CHILD IS XX – A GIRL IF THIS PERSON FLIPS TAILS, THE CHILD IS XY- A BOY AT THE END OF THIS LAB, HAND IN THE ANSWERS TO THE TERMS, THE CHARTS FILLED IN WITH YOUR ALLELES, GENOTYPE AND PHENOTYPE AND A COLORED DRAWING OF YOUR “BABY.” Purpose: To demonstrate the principles of Mendelian genetics and sex determination, including the concepts of allele, phenotype, genotype, dominant, recessive, codominant, homozygous and heterozygous by creating a simulated baby. Materials: Two pennies, art supplies, paper. Procedure: 1) Working with a partner, determine the genotype of the baby by flipping pennies. "Mom" flips one penny to choose an allele for her egg and "Dad" flips the other to choose an allele for his sperm. (Note that the gender of the baby is a special case and is determined by dad alone. Boys are XY and girls are XX. Mom can give only an X but dad can give either an X or a Y.) 2) Record the alleles which resulted from the coin flips, and put "sperm and egg" together. (You cannot pick the traits you want; life doesn't work that way!) Write down baby's genotype for each trait in Table 1. Heads represents allele #1 and tails represents allele #2. 3) Record the baby's phenotype in Table 1. Note: Dominant alleles are written with an uppercase letter and recessive alleles are written as lowercase letters. Dominant alleles mask the expression of recessive ones. Codominant alleles are written as uppercase letters with a subscript. Co-dominant alleles result in a phenotype that is blended. 4) Repeat steps 1, 2, and 3 for all traits and then draw, color, and name your creation. Remember that you are drawing a baby's face - not a child's or an adult's (no tattoos, no mustaches, no pierced ears, noses, etc., and not too much hair!) Name of people in group :_______________________________________________________________________ ________________________________________________________________________ Period:___________________________ Questions: 1. Why is the coin flip used to represent the selection of alleles? 2. Define the following terms: allele- phenotype- genotype- dominant- recessive- codominant- homozygous- heterozygous- chromosomelocusgeneResults: Keep track of the toss of each coin; if the person representing the female gets tails, the trait letter is lower case; heads, it would be the upper case letter. The other person flips their coin and lets’ say they get heads. TRAIT for face shape uses the letters R for round shape and r for square shape. If the first person got tails, the letter in the allele from mom would be “r” If the second person get heads, the letter in the allele from dad would be R The genotype would be Rr. The phenotype would be R Table 1: Check here indicating whether you are the mom or the dad and fill in the data below. Mom's Name: ________________ Dad's Name _________________ Baby's Name: ________________ Trait Allele from Mom Allele from Dad Genotype Phenotype Gender ______X______ _____________ _____________ _____________ Face Shape _____________ _____________ _____________ _____________ Chin Shape _____________ _____________ _____________ _____________ Chin Dimple _____________ _____________ _____________ _____________ Freckles _____________ _____________ _____________ _____________ Cheek Dimples _____________ _____________ _____________ _____________ Lip Thickness _____________ _____________ _____________ _____________ Eye Brows _____________ _____________ _____________ _____________ Eye Shape _____________ _____________ _____________ _____________ Eyelashes _____________ _____________ _____________ _____________ Ear Shape _____________ _____________ _____________ _____________ Ear Lobes _____________ _____________ _____________ _____________ Widow's Peak _____________ _____________ _____________ _____________ Hair Curliness _____________ _____________ _____________ _____________ Eyebrow Color _____________ _____________ _____________ _____________ Eye Width _____________ _____________ _____________ _____________ Eye Size _____________ _____________ _____________ _____________ Mouth Size _____________ _____________ _____________ _____________ Nose Size _____________ _____________ _____________ _____________ Birth Mark _____________ _____________ _____________ _____________ Skin Tone _____________ _____________ _____________ _____________ Polygenic Trait Alleles from Mom Alleles from Dad Genotype Phenotype Hair Color #1____ #2____ #1____ #2____ __ __ /__ __ _____________ Eye Color #1____ #2____ #1____ #2____ __ __ /__ __ _____________ Genotype/Phenotype Reference Sheet Trait Face Shape Chin Shape Chin Dimple Freckles Cheek Dimples Lip Thickness Eye Brows Genotype/Phenotype (Homozygous for Allele 1) Ear Shape Ear Lobes Widow's Peak Hair Curliness Eyebrow Color Genotype/Phenotype (Homozygous for Allele #2) RR Rr rr Round Round Square NN Nn nn Noticeable Noticeable Less Noticeable AA Aa aa Absent Absent Present FF Ff ff Present Present Absent DD Dd dd Present Present Absent TT Tt tt Thick Thick Thin BB Bb bb Bushy Bushy Fine WW Ww ww Wide Wide Round LL Ll ll Long Long Short RR Rr rr Long Long Round FF Ff ff Free Free Attached Eye Shape Eyelashes Genotype/Phenotype (Heterozygous) WW Ww ww Present Present Absent C 1 C1 C 1 C2 C 2 C2 Curly Wavy Strait D1D1 D1D2 D2D2 Darker than hair W1W1 Eye Width Eye Size Mouth Size Nose Size Birth Mark (mole) Skin Tone Hair Color Eye Color Close Together Same as hair Lighter than hair W1W 2 W2W 2 Average Far apart S1S 1 S1S 2 S2 S2 Large Medium Small M1 M 1 M1 M 2 M2 M 2 Wide Medium Narrow P1P1 P 1P2 P 2P2 Small Medium Large B1B1 B1B2 B2B2 Left cheek Absent Right cheek S 1S1 S1 S2 S 2S2 Light Medium Dark AABB=Black AaBB=Dark Brown aaBB=Blond AABb=Black AaBb=Light Brown aaBb=Blond AAbb=Red Aabb=Dark Blond aabb=white (albino) AABB=Deep Brown AaBB=Greenish Brown aaBB=Green AABb=Deep Brown AaBb=Light Brown aaBb=Light Blue AAbb=Brown Aabb=Gray-Blue aabb=Pink Human Trait Activity Introduction: When students practice Punnett squares, teachers often give them problems involving plants or small mammals. Students may enjoy finding out about some of their traits. For this exercise, all dominant traits will be heterozygous. This will make the results a little more interesting, and will save time and paper. After the students determine their traits and their genes, they will 'mate' with their partner. For each trait, the partners will set up and complete a Punnett square and determine the phenotypic ration of the offspring. If help is needed in determining what the traits look like, refer to the Create-A-Baby-Lab. Objectives: 1. To practice Punnett squares. 2. To investigate genetic traits that affect themselves. Materials: 1. Partner ('Mate') 2. Pens or pencils Procedure: 1. 2. 3. 4. 5. 6. Mark off your traits in Table 1. Determine and record your gene make up in Table 2. Mark off your partner's traits in Table 1. Determine your partner's genetic make up in Table 2. Using the information in Table 2, set up and complete a Punnett square for each of the traits. Determine the phenotypic ration for each trait. Results: Table 1: Your phenotype and your partner's phenotype. (Remember: a dominant trait is automatically heterozygous for this activity.) Dominant Traits You Partner Recessive Traits Trait You Dark Hair (Dd) Widows' Peak (Ww) Free Ear Lobes (Ee) Partner Freckles (Ff) Right Handed (Rr) Straight thumb (Ss) Tongue Roller (Tt) Trait Light Hair (dd) Straight Hair (ww) Attached Ear Lobes (ee) No freckles (ff) Left Handed (rr) Hitch-hikers thumb (ss) Non-tongue Roller (tt) Table 2: Gene Make Up Record genotypes in Table 2. Trait Your genes Partner's genes Hair color Hair line Ear lobes Freckles Hand Preference Thumb Tongue Punnett Squares: For each trait above, cross you and your partner’s genotype. Record the Phenotypic ratio. Phenotypic Ratio:_________________________ Phenotypic Ratio:_________________________ Phenotypic Ratio:_________________________ Phenotypic Ratio:_________________________ Phenotypic Ratio:_________________________