www.dynamicpapers.com Cambridge International Examinations Cambridge International General Certificate of Secondary Education * 8 8 5 9 8 1 2 6 6 1 * 0610/42 BIOLOGY Paper 4 Theory (Extended) February/March 2018 1 hour 15 minutes Candidates answer on the Question Paper. No Additional Materials are required. READ THESE INSTRUCTIONS FIRST Write your Centre number, candidate number and name on all the work you hand in. Write in dark blue or black pen. You may use an HB pencil for any diagrams or graphs. Do not use staples, paper clips, glue or correction fluid. DO NOT WRITE IN ANY BARCODES. Answer all questions. Electronic calculators may be used. You may lose marks if you do not show your working or if you do not use appropriate units. At the end of the examination, fasten all your work securely together. The number of marks is given in brackets [ ] at the end of each question or part question. This syllabus is approved for use in England, Wales and Northern Ireland as a Cambridge International Level 1/Level 2 Certificate. This document consists of 17 printed pages and 3 blank pages. DC (SC/FC) 145585/4 © UCLES 2018 [Turn over www.dynamicpapers.com 2 1 (a) (i) Fig. 1.1 is a branching key used to identify different species of bacteria. Do the bacteria have flagella? Yes No Do the bacteria have more than one flagellum? Yes No Do the bacteria have flagella attached at one end only? Yes C Do the bacteria have a spiral shape? Yes A No Do the bacteria form a chain? B No Yes D No E F Fig. 1.1 Fig. 1.2 shows six different species of bacteria. Use the key to identify the six different species of bacteria. Write the letters on the lines in Fig. 1.2. ..................................... ..................................... ..................................... ..................................... ..................................... ..................................... © UCLES 2018 Fig. 1.2 0610/42/F/M/18 [5] 3 (ii) www.dynamicpapers.com State the name of the kingdom that bacteria belong to. ...................................................................................................................................... [1] (b) State one similarity between the structure of bacteria and the structure of viruses. ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[1] (c) Fig. 1.3 is a photomicrograph of Vibrio cholerae, the bacterium that causes cholera. 45 mm magnification ×17 300 Fig. 1.3 (i) Write the formula that would be used to calculate the actual length of the bacterium (not including the flagellum) in Fig. 1.3. [1] © UCLES 2018 0610/42/F/M/18 [Turn over 4 (ii) www.dynamicpapers.com The actual length of the bacterium shown in Fig. 1.3 is 0.0026 mm. Convert this value to micrometres (µm). Space for working. ..................................................... µm [1] (d) (i) Describe and explain the effects of cholera bacteria on the gut. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[4] (ii) Suggest one treatment for cholera. .......................................................................................................................................[1] [Total: 14] © UCLES 2018 0610/42/F/M/18 5 www.dynamicpapers.com BLANK PAGE © UCLES 2018 0610/42/F/M/18 [Turn over www.dynamicpapers.com 6 2 A study estimated the number of people with chronic obstructive pulmonary disease (COPD) in India. Data were collected from two groups of people, those who lived in cities and those who lived in villages. Fig. 2.1 shows the results. 18 Key: city 16 village 14 12 estimated numbers of people with 10 COPD / million 8 6 4 2 0 1996 2001 2006 year Fig. 2.1 © UCLES 2018 0610/42/F/M/18 2011 2016 7 www.dynamicpapers.com (a) Compare the number of people with COPD in cities with the number of people with COPD in villages and suggest reasons for the differences. Use the data in Fig. 2.1 to support your answer. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[6] (b) (i) Explain how the body prevents particles in inspired air from reaching the gas exchange surfaces. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[4] © UCLES 2018 0610/42/F/M/18 [Turn over 8 (ii) www.dynamicpapers.com State two ways in which the composition of inspired air differs from the composition of expired air. 1 ........................................................................................................................................ 2 ........................................................................................................................................ [2] (c) Alveoli are well-ventilated to provide efficient gas exchange. (i) State the name of the muscles that cause the ribs to move during ventilation. .......................................................................................................................................[1] (ii) During inspiration the pressure and volume in the thorax changes. State these changes. pressure ............................................................................................................................ volume ............................................................................................................................... [1] [Total: 14] © UCLES 2018 0610/42/F/M/18 www.dynamicpapers.com 9 3 (a) Ecologists studied an area of woodland and estimated the biomass of each trophic level for one of the food chains in the woodland. Some students wanted to use the data to draw a pyramid of biomass for the food chain. Table 3.1 shows the students’ table. The students added a column to calculate the width of the bars they would need to draw. Table 3.1 trophic level biomass / g m−2 width of bar / cm 120 12.0 1 producer 2 primary consumer 48 4.8 3 secondary consumer 16 1.6 4 tertiary consumer 2 (i) Complete Table 3.1 by calculating the missing value and writing it in the table. (ii) Using the information in Table 3.1, draw a pyramid of biomass. [1] Label each bar with the trophic level. [3] (b) A type of organism gains energy from waste organic material from all trophic levels. State the name of this type of organism. ...............................................................................................................................................[1] © UCLES 2018 0610/42/F/M/18 [Turn over 10 (c) (i) www.dynamicpapers.com Outline how organisms in the first trophic level of the woodland food chain produce biomass using energy from the Sun. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[3] (ii) Explain why the fourth trophic level has the least biomass in this food chain. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[3] (d) The woodland is a conservation area. Outline the possible benefits of conserving this specific area of woodland. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[3] [Total: 14] © UCLES 2018 0610/42/F/M/18 www.dynamicpapers.com 11 4 Fig. 4.1 is a diagram of the human female reproductive system. A F B E D C Fig. 4.1 (a) Complete Table 4.1 to show the letter and the name of each of the structures that perform these functions. Table 4.1 function letter name releases oestrogen site of fertilisation site of implantation dilates during the process of birth [4] (b) Fertilisation is the fusion of the nuclei of a male gamete and a female gamete resulting in a zygote. State the number of chromosomes present in a human: female gamete ........................... zygote ........................................ © UCLES 2018 [2] 0610/42/F/M/18 [Turn over www.dynamicpapers.com 12 (c) Chlamydia is a sexually transmitted infection (STI). Fig. 4.2 shows the number of reported cases of chlamydia in females in each age group in one country. 400 000 350 000 300 000 number of chlamydia cases in 2008 250 000 200 000 150 000 100 000 50 000 0 10–14 15–19 20–24 25–29 30–34 35–39 40–44 45–54 55–64 65+ age group / years Fig. 4.2 Describe the results shown by the data in Fig. 4.2. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[3] (d) Chlamydia is caused by a bacterium. (i) Suggest a treatment for chlamydia. .......................................................................................................................................[1] (ii) State the name of one other STI. .......................................................................................................................................[1] © UCLES 2018 0610/42/F/M/18 13 (iii) www.dynamicpapers.com Complete the sentences about the spread of STIs. STIs are transmitted through the transfer of ............................................... during sexual contact. One way individuals can avoid the spread of STIs is to use a type of ............................................... contraception. One example of this type of contraception is ............................................... . [3] [Total: 14] © UCLES 2018 0610/42/F/M/18 [Turn over www.dynamicpapers.com 14 5 2,4-D is a synthetic plant auxin that is used as a weedkiller. Researchers investigated the effectiveness of different treatments of 2,4-D on the control of the weed Conyza canadensis in fields of maize, Zea mays. The results are shown in Table 5.1. Table 5.1 treatment time of treatment day 7 A mean dry mass of weeds / g per m2 weed density / number of weeds per m2 7.40 6.20 3.90 4.90 0.50 1.20 0.66 1.90 ✓ 0.18 0.98 ✓ ✓ 0.07 0.29 ✓ ✓ 0.08 0.51 day 23 ✓ B ✓ C ✓ D ✓ E ✓ F G (a) (i) day 33 ✓ ✓ Maize farmers that had been using treatment C were advised by the researchers to change to treatment F. Discuss the advantages and disadvantages of changing to treatment F. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[4] (ii) Suggest two factors that could decrease the effectiveness of 2,4-D. 1 ........................................................................................................................................ 2 ........................................................................................................................................ [2] © UCLES 2018 0610/42/F/M/18 15 (iii) www.dynamicpapers.com Explain how 2,4-D acts as a weedkiller. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[3] (b) Auxin causes the shoots of a plant to grow away from gravity. State the name of this response. ...............................................................................................................................................[2] [Total: 11] © UCLES 2018 0610/42/F/M/18 [Turn over www.dynamicpapers.com 16 6 (a) Define the term chemical digestion. ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[2] (b) A student investigated the activity of the digestive enzyme pepsin. Fig. 6.1 shows the apparatus used in the investigation. test-tube 1 egg white solution and pepsin test-tube 2 egg white solution, pepsin and hydrochloric acid test-tube 3 egg white solution, boiled pepsin and hydrochloric acid test-tube 4 egg white solution and hydrochloric acid stop-clock Fig. 6.1 The appearance of the four test-tubes was recorded at 0 and 5 minutes. The protein in the egg white solution gives the solution a cloudy appearance. The cloudy appearance clears when the protein in the egg white solution breaks down. Table 6.1 shows the results. Table 6.1 test-tube © UCLES 2018 contents appearance at 0 mins appearance after 5 mins 1 egg white solution, pepsin cloudy less cloudy 2 egg white solution, pepsin, hydrochloric acid cloudy clear 3 egg white solution, boiled pepsin, hydrochloric acid cloudy cloudy 4 egg white solution, hydrochloric acid cloudy cloudy 0610/42/F/M/18 17 (i) www.dynamicpapers.com Explain the results shown for test-tubes 1, 2 and 3 in Table 6.1. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[5] (ii) Explain the purpose of test-tube 4. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[2] (iii) State the name of the organ in the body that produces pepsin. .......................................................................................................................................[1] © UCLES 2018 0610/42/F/M/18 [Turn over 18 www.dynamicpapers.com (c) Maltase is another digestive enzyme. Describe the action of maltase and state where it acts in the alimentary canal. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[3] [Total: 13] © UCLES 2018 0610/42/F/M/18 19 BLANK PAGE © UCLES 2018 0610/42/F/M/18 www.dynamicpapers.com 20 www.dynamicpapers.com BLANK PAGE Permission to reproduce items where third-party owned material protected by copyright is included has been sought and cleared where possible. Every reasonable effort has been made by the publisher (UCLES) to trace copyright holders, but if any items requiring clearance have unwittingly been included, the publisher will be pleased to make amends at the earliest possible opportunity. To avoid the issue of disclosure of answer-related information to candidates, all copyright acknowledgements are reproduced online in the Cambridge International Examinations Copyright Acknowledgements Booklet. This is produced for each series of examinations and is freely available to download at www.cie.org.uk after the live examination series. Cambridge International Examinations is part of the Cambridge Assessment Group. Cambridge Assessment is the brand name of University of Cambridge Local Examinations Syndicate (UCLES), which is itself a department of the University of Cambridge. © UCLES 2018 0610/42/F/M/18 www.dynamicpapers.com Cambridge International Examinations Cambridge International General Certificate of Secondary Education * 1 6 3 0 2 3 2 2 6 2 * 0610/41 BIOLOGY May/June 2018 Paper 4 Theory (Extended) 1 hour 15 minutes Candidates answer on the Question Paper. No Additional Materials are required. READ THESE INSTRUCTIONS FIRST Write your Centre number, candidate number and name on all the work you hand in. Write in dark blue or black pen. You may use an HB pencil for any diagrams or graphs. Do not use staples, paper clips, glue or correction fluid. DO NOT WRITE IN ANY BARCODES. Answer all questions. Electronic calculators may be used. You may lose marks if you do not show your working or if you do not use appropriate units. At the end of the examination, fasten all your work securely together. The number of marks is given in brackets [ ] at the end of each question or part question. This syllabus is approved for use in England, Wales and Northern Ireland as a Cambridge International Level 1/Level 2 Certificate. This document consists of 17 printed pages and 3 blank pages. DC (SC/AR) 145577/4 © UCLES 2018 [Turn over 2 BLANK PAGE © UCLES 2018 0610/41/M/J/18 www.dynamicpapers.com www.dynamicpapers.com 3 1 (a) The reactions of chemical digestion are catalysed by enzymes. Fig. 1.1 shows the stages of an enzyme-catalysed reaction. enzyme A B C D Fig. 1.1 State the names of A to D in Fig. 1.1. A ............................................................................................................................................... B ............................................................................................................................................... C ............................................................................................................................................... D ............................................................................................................................................... [4] © UCLES 2018 0610/41/M/J/18 [Turn over 4 www.dynamicpapers.com (b) Explain the importance of chemical digestion. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[2] (c) Fig. 1.2 shows the human alimentary canal and associated organs. The functions of some of these parts of the body are given in Table 1.1. A M B L C D K J H E F G Fig. 1.2 © UCLES 2018 0610/41/M/J/18 www.dynamicpapers.com 5 Complete Table 1.1. One row has been done for you. Table 1.1 function letter from Fig. 1.2 name of structure site of starch digestion reabsorption of water secretion of pepsin site of maltose digestion secretion of bile storage of faeces F rectum secretion of lipase and trypsin [6] [Total: 12] © UCLES 2018 0610/41/M/J/18 [Turn over 6 2 www.dynamicpapers.com (a) Adaptive features are defined as the inherited features of an organism that increase its fitness. State what is meant by fitness in this context. ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[1] (b) Rodents are the most common mammals in many hot deserts. Fig. 2.1 shows the lesser Egyptian jerboa, Jaculus jaculus, which lives in North Africa and the Middle East in areas that have high daytime temperatures and very little rainfall. Fig. 2.1 Like many desert-living mammals, jerboas are active at night. Suggest two features of J. jaculus that adapt it to each of the following challenges of living in desert ecosystems: (i) very high daytime temperatures 1 ........................................................................................................................................ 2 ........................................................................................................................................ [2] (ii) very little or no light at night 1 ........................................................................................................................................ 2 ........................................................................................................................................ [2] © UCLES 2018 0610/41/M/J/18 7 www.dynamicpapers.com (c) A scientist studied communities in different parts of a desert and estimated the biomass of the organisms in each area. He divided the organisms into four groups according to their roles in the food web as shown in Table 2.1. Detritivores are animals that eat dead organisms or parts of organisms. Table 2.1 groups of organisms in the food web biomass / g per m2 producers 480 herbivores 220 detritivores 120 carnivores 40 Some of these results are shown as a pyramid of biomass in Fig. 2.2. herbivores and detritivores producers Fig. 2.2 (i) Use the information in Table 2.1 to complete the pyramid of biomass in Fig. 2.2. (ii) The scientist observed the detritivores and decided to include them with herbivores in this pyramid of biomass. [2] Suggest what the scientist discovered about the detritivores that made him make this decision. ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[1] © UCLES 2018 0610/41/M/J/18 [Turn over 8 (iii) www.dynamicpapers.com Explain why there are rarely more than four or five trophic levels in ecosystems. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[2] (iv) Explain the advantages of presenting information about food webs as a pyramid of biomass and not as a pyramid of numbers. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[3] [Total: 13] © UCLES 2018 0610/41/M/J/18 9 3 www.dynamicpapers.com A student cut a section of a root and made an outline drawing of the distribution of tissues as shown in Fig. 3.1. Fig. 3.1 (a) (i) (ii) Identify the position of the xylem tissue by drawing a label line and the letter X on Fig. 3.1. [1] State why xylem is a tissue. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[2] (b) Water absorbed by the roots moves through the stem and enters the leaves. Most of this water is lost in transpiration. Explain how the internal structure of leaves results in the loss of large quantities of water in transpiration. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[3] [Total: 6] © UCLES 2018 0610/41/M/J/18 [Turn over 10 BLANK PAGE © UCLES 2018 0610/41/M/J/18 www.dynamicpapers.com 11 4 www.dynamicpapers.com The flow of blood through the skin can be investigated by using a flow-meter. Fig. 4.1 shows a flow-meter above a section through the skin. flow-meter T P skin Q S ring of muscle R Not drawn to scale Fig. 4.1 (a) (i) State the name of cell P. .......................................................................................................................................[1] (ii) State the types of blood vessel labelled Q, S and T. Q ....................................................................................................................................... S ........................................................................................................................................ T ........................................................................................................................................ [3] (iii) © UCLES 2018 State the name of the tissue at R that provides insulation. .......................................................................................................................................[1] 0610/41/M/J/18 [Turn over www.dynamicpapers.com 12 (b) The blood flow through the skin of some volunteers was measured with a flow-meter when their skin was exposed to different temperatures. Capsaicin is a compound that gives people the sensation of feeling hot when it is put on the skin. Researchers applied capsaicin to the skin of the volunteers and again measured the blood flow through their skin at different temperatures. Fig. 4.2 shows the results. 100 90 80 average blood flow as a percentage of maximum blood flow with capsaicin 70 60 50 40 without capsaicin 30 20 10 0 15 20 25 30 35 temperature of the skin surface / °C 40 45 Fig. 4.2 (i) Use the information in Fig. 4.2 to describe the effect of increasing the temperature of the skin surface on blood flow to the skin without capsaicin. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[3] © UCLES 2018 0610/41/M/J/18 13 (ii) www.dynamicpapers.com Explain the mechanism that increases blood flow through the skin. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[3] (iii) State the difference between the average blood flow for the treatments (with and without capsaicin) at 35 °C. Space for working. ....................................................... % [1] (iv) The researchers thought that capsaicin stimulated receptors in the skin. Explain the process by which capsaicin could reach these receptors. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[3] © UCLES 2018 0610/41/M/J/18 [Turn over 14 www.dynamicpapers.com (c) Explain the importance of regulating body temperature in humans. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[4] (d) Body temperature is controlled by both hormones and nerves. Explain how co-ordination by hormones differs from co-ordination by nerves. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[3] [Total: 22] © UCLES 2018 0610/41/M/J/18 15 www.dynamicpapers.com BLANK PAGE © UCLES 2018 0610/41/M/J/18 [Turn over www.dynamicpapers.com 16 5 (a) State the balanced chemical equation for aerobic respiration. ...............................................................................................................................................[2] (b) Researchers in the Czech Republic investigated oxygen consumption in horses. They measured the oxygen consumption of the horses while they were exercising at four different paces: walking, trotting, cantering and galloping. The results are shown in Fig. 5.1. 120 110 100 90 average rate 80 of oxygen consumption 70 / cm3 kg–1 min–1 60 50 40 30 20 10 0 walking trotting cantering type of exercise Fig. 5.1 © UCLES 2018 0610/41/M/J/18 galloping 17 www.dynamicpapers.com Calculate the percentage increase in the average rate of oxygen consumption as the horses change from walking to trotting. Show your working. ................................ % [2] (c) The researchers also calculated the oxygen debt for each type of exercise. They found that the horses developed a larger oxygen debt when they exercised by galloping and cantering rather than when they walked. Explain why the horses developed an oxygen debt when they exercised. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[3] (d) Describe how the horses would recover from an oxygen debt when they stop exercising. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[4] © UCLES 2018 0610/41/M/J/18 [Total:11] [Turn over www.dynamicpapers.com 18 6 (a) Fig. 6.1 is a diagram of the human female reproductive system. T S V W R X Y Fig. 6.1 (i) Complete Table 6.1 by stating the letter from Fig. 6.1 that identifies the structure where each process occurs. Table 6.1 process letter from Fig. 6.1 meiosis fertilisation implantation [3] (ii) State the name of the part of the female reproductive system labelled S in Fig. 6.1. ...................................................................................................................................... [1] © UCLES 2018 0610/41/M/J/18 19 www.dynamicpapers.com (b) Fig. 6.2 is a diagram of a human sperm cell. acrosome nucleus flagellum mitochondria Fig. 6.2 (i) Write the formula that would be used to calculate the magnification of the diagram. [1] (ii) The actual length of the sperm cell in Fig. 6.2 is 0.055 mm. Convert this value to micrometres (μm). Space for working. .................................................... μm [1] (c) Explain why the nuclei of sperm cells differ from those of other cells in the male. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[2] © UCLES 2018 0610/41/M/J/18 [Turn over 20 www.dynamicpapers.com (d) Explain the roles of the flagellum, the mitochondria and the acrosome in sperm cells. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[6] (e) Explain why the sex of a child is determined by its father. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[2] [Total: 16] Permission to reproduce items where third-party owned material protected by copyright is included has been sought and cleared where possible. Every reasonable effort has been made by the publisher (UCLES) to trace copyright holders, but if any items requiring clearance have unwittingly been included, the publisher will be pleased to make amends at the earliest possible opportunity. To avoid the issue of disclosure of answer-related information to candidates, all copyright acknowledgements are reproduced online in the Cambridge International Examinations Copyright Acknowledgements Booklet. This is produced for each series of examinations and is freely available to download at www.cie.org.uk after the live examination series. Cambridge International Examinations is part of the Cambridge Assessment Group. Cambridge Assessment is the brand name of University of Cambridge Local Examinations Syndicate (UCLES), which is itself a department of the University of Cambridge. © UCLES 2018 0610/41/M/J/18 www.dynamicpapers.com Cambridge International Examinations Cambridge International General Certificate of Secondary Education * 7 6 6 8 0 6 5 7 2 5 * 0610/42 BIOLOGY May/June 2018 Paper 4 Theory (Extended) 1 hour 15 minutes Candidates answer on the Question Paper. No Additional Materials are required. READ THESE INSTRUCTIONS FIRST Write your Centre number, candidate number and name on all the work you hand in. Write in dark blue or black pen. You may use an HB pencil for any diagrams or graphs. Do not use staples, paper clips, glue or correction fluid. DO NOT WRITE IN ANY BARCODES. Answer all questions. Electronic calculators may be used. You may lose marks if you do not show your working or if you do not use appropriate units. At the end of the examination, fasten all your work securely together. The number of marks is given in brackets [ ] at the end of each question or part question. This syllabus is approved for use in England, Wales and Northern Ireland as a Cambridge International Level 1/Level 2 Certificate. This document consists of 16 printed pages and 4 blank pages. DC (NF/SW) 145576/4 © UCLES 2018 [Turn over 2 BLANK PAGE © UCLES 2018 0610/42/M/J/18 www.dynamicpapers.com www.dynamicpapers.com 3 1 (a) Red pandas, Ailurus fulgens, and humans have a similar arrangement of teeth. Fig. 1.1 shows a section through one tooth of a red panda. Fig. 1.2 shows the side view of the lower jaw of a red panda. A B C D Fig. 1.1 (i) E F Fig. 1.2 State the names of the structures labelled A to F in Fig. 1.1 and Fig. 1.2. A ........................................................................................................................................ B ........................................................................................................................................ C ........................................................................................................................................ D ........................................................................................................................................ E ........................................................................................................................................ F ........................................................................................................................................ [3] (ii) State the type of digestion that breaks down large pieces of food. ...................................................................................................................................... [1] (b) Food that sticks to the teeth can be used by bacteria for anaerobic respiration. This type of respiration releases a substance that can cause tooth decay. (i) State the type of substance released by the bacteria, during respiration, that causes tooth decay. ...................................................................................................................................... [1] © UCLES 2018 0610/42/M/J/18 [Turn over 4 (ii) www.dynamicpapers.com State the names of the two parts of a tooth that are dissolved by the substance released by bacterial respiration. 1 ......................................................................................................................................... 2 ......................................................................................................................................... [2] (c) The teeth of red pandas do not decay as much as human teeth. Suggest the component of a human diet that causes teeth to decay as a result of bacterial respiration. .............................................................................................................................................. [1] [Total: 8] © UCLES 2018 0610/42/M/J/18 5 2 www.dynamicpapers.com Mangrove trees are hydrophytes because they grow in water. Fig. 2.1 shows a young mangrove tree. Fig. 2.1 (a) An adaptive feature is a feature that increases the fitness of an organism. (i) Define the term fitness. ........................................................................................................................................... ........................................................................................................................................... ...................................................................................................................................... [1] (ii) Mangrove trees have many aerial roots and floating seeds. Suggest how these adaptive features allow mangrove trees to survive in water. many aerial roots ............................................................................................................... ........................................................................................................................................... ........................................................................................................................................... floating seeds .................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... [2] © UCLES 2018 0610/42/M/J/18 [Turn over 6 www.dynamicpapers.com (b) Fig. 2.2 shows a food chain in a mangrove forest. mangrove tree fiddler crab seagull Fig. 2.2 Table 2.1 gives the number of organisms and their biomass in a mangrove forest. Table 2.1 organism mangrove trees fiddler crabs seagulls (i) number of organisms biomass of organisms / kg 1 000 450 000 7 500 000 8 000 150 000 1 200 Estimate the biomass of one fiddler crab in grams. Write your answer to two significant figures. Show your working. ............................ g [2] (ii) Sketch a pyramid of numbers, using the information in Table 2.1, for the food chain shown in Fig. 2.2. Write the number of each trophic level on the appropriate part of your pyramid. © UCLES 2018 0610/42/M/J/18 [3] 7 (iii) www.dynamicpapers.com Explain why the shape of a pyramid of biomass, for the information given in Table 2.1, would be different from the shape of your pyramid of numbers. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ...................................................................................................................................... [4] [Total: 12] © UCLES 2018 0610/42/M/J/18 [Turn over www.dynamicpapers.com 8 3 Aphids are insects that feed on the phloem sap in plants. Fig. 3.1 shows a diagram of an aphid with its mouth parts inserted into the stem of a plant. phloem xylem Fig. 3.1 (a) The mouth parts of the aphid reach the phloem tissue of the stem. (i) State the name of the foods the aphid could suck out of the phloem tissue. 1 ......................................................................................................................................... 2 ......................................................................................................................................... [2] (ii) Explain the role of phloem in plant transport. Use the words source and sink in your answer. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ...................................................................................................................................... [4] © UCLES 2018 0610/42/M/J/18 9 www.dynamicpapers.com (b) Fig. 3.1 shows some of the features of xylem. Describe how xylem is adapted for its functions. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... .............................................................................................................................................. [6] (c) Some farmers spray their crops with insecticides to kill pests such as aphids. Explain the benefits of killing pests. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... .............................................................................................................................................. [2] [Total: 14] © UCLES 2018 0610/42/M/J/18 [Turn over 10 4 www.dynamicpapers.com One of the roles of the Centers for Disease Control and Prevention (CDC) in Atlanta, US, is to try to reduce the number of people who are infected with pathogens. The CDC conducted a survey. They asked women which, if any, contraceptive methods they used. (a) Suggest why the CDC collected data on contraceptive methods. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... .............................................................................................................................................. [3] Fig. 4.1 shows the results of the survey. 90 80 70 60 percentage 50 of women in the survey 40 30 20 10 0 any method condoms/ femidoms contraceptive pills contraceptive method Fig. 4.1 © UCLES 2018 0610/42/M/J/18 other chemical methods 11 (b) (i) www.dynamicpapers.com State two hormones that are used in contraceptive pills. 1 ......................................................................................................................................... 2 ......................................................................................................................................... [2] (ii) Suggest why contraceptive pills do not contain FSH. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ...................................................................................................................................... [3] (iii) Give one example of ‘other chemical methods’ (fourth bar) that could be included in the bar in Fig. 4.1. ...................................................................................................................................... [1] (iv) State two methods of birth control that were not listed in the survey. 1 ......................................................................................................................................... 2 ......................................................................................................................................... [2] (v) The percentage of the last three bars in Fig. 4.1 added together is 90%. Suggest why the percentage of women who used any type of contraceptive method (first bar) is not equal to the sum of the last three bars. ........................................................................................................................................... ........................................................................................................................................... ...................................................................................................................................... [1] [Total: 12] © UCLES 2018 0610/42/M/J/18 [Turn over 12 5 www.dynamicpapers.com Fig. 5.1 shows an adult fly, Chrysomya megacephala. Fig. 5.1 (a) State three visible features from Fig. 5.1 that could be used to distinguish adult insects from other arthropods. 1 ................................................................................................................................................ 2 ................................................................................................................................................ 3 ................................................................................................................................................ [3] (b) Fly larvae are immature insects that are often used in experiments on respiration. Give the balanced chemical equation for aerobic respiration. .............................................................................................................................................. [2] © UCLES 2018 0610/42/M/J/18 www.dynamicpapers.com 13 (c) A respirometer is shown in Fig. 5.2. It can be used to estimate an organism’s rate of respiration. 8 7 6 5 4 3 2 1 0 droplet of oil water-bath fly larvae wire mesh soda lime Fig. 5.2 (i) Complete the sentences: A respirometer can be used to calculate the ............................. of oxygen used by the fly larvae by measuring the ............................. the droplet of oil moves in one minute. A water-bath is used to ............................. the temperature of the apparatus. (ii) [3] The soda lime in the respirometer absorbs carbon dioxide. Explain why this is important in this investigation. ........................................................................................................................................... ........................................................................................................................................... ...................................................................................................................................... [1] (iii) Fly larvae respire to release energy. State two uses of energy in a fly larva. 1 ......................................................................................................................................... © UCLES 2018 2 ......................................................................................................................................... [2] 0610/42/M/J/18 [Turn over 14 www.dynamicpapers.com (d) A student used a respirometer to investigate the effect of temperature on the rate of respiration of germinating seeds. Predict the results of this investigation and explain your prediction. prediction .................................................................................................................................. ................................................................................................................................................... ................................................................................................................................................... explanation ............................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... [4] [Total: 15] © UCLES 2018 0610/42/M/J/18 www.dynamicpapers.com 15 6 Bacteria are useful in biotechnology and genetic engineering. Fig. 6.1 shows a photomicrograph of a bacterium. magnification ×27 000 Fig. 6.1 (a) State the name of the process that is taking place in Fig. 6.1. .............................................................................................................................................. [1] (b) (i) (ii) Write the formula that would be used to calculate the actual width of the bacterium. [1] The actual width of the bacterium is 0.0008 mm. Convert this value to micrometres (μm). Space for working. ................................. μm [1] (c) Genetically modified bacteria can produce human insulin. (i) State the name of the disease that can be treated with insulin injections. ...................................................................................................................................... [1] © UCLES 2018 0610/42/M/J/18 [Turn over 16 (ii) www.dynamicpapers.com Insulin is a protein. Describe the process of using bacteria in genetic engineering to produce human proteins. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ...................................................................................................................................... [5] (d) Genetically modified bacteria are often grown in fermenters. (i) Suggest why steam is used to clean fermenters. ........................................................................................................................................... ........................................................................................................................................... ...................................................................................................................................... [2] (ii) State three conditions inside a fermenter that are measured and controlled. 1 ......................................................................................................................................... 2 ......................................................................................................................................... 3 ......................................................................................................................................... [3] (iii) State the name of one commercial product, other than insulin, that is made in fermenters. ...................................................................................................................................... [1] © UCLES 2018 0610/42/M/J/18 17 www.dynamicpapers.com (e) Crop plants can also be genetically modified. Describe the advantages of genetically modifying crops. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... .............................................................................................................................................. [4] [Total: 19] © UCLES 2018 0610/42/M/J/18 18 BLANK PAGE © UCLES 2018 0610/42/M/J/18 www.dynamicpapers.com 19 BLANK PAGE © UCLES 2018 0610/42/M/J/18 www.dynamicpapers.com 20 www.dynamicpapers.com BLANK PAGE Permission to reproduce items where third-party owned material protected by copyright is included has been sought and cleared where possible. Every reasonable effort has been made by the publisher (UCLES) to trace copyright holders, but if any items requiring clearance have unwittingly been included, the publisher will be pleased to make amends at the earliest possible opportunity. To avoid the issue of disclosure of answer-related information to candidates, all copyright acknowledgements are reproduced online in the Cambridge International Examinations Copyright Acknowledgements Booklet. This is produced for each series of examinations and is freely available to download at www.cie.org.uk after the live examination series. Cambridge International Examinations is part of the Cambridge Assessment Group. Cambridge Assessment is the brand name of University of Cambridge Local Examinations Syndicate (UCLES), which is itself a department of the University of Cambridge. © UCLES 2018 0610/42/M/J/18 www.dynamicpapers.com Cambridge International Examinations Cambridge International General Certificate of Secondary Education * 4 9 9 6 1 4 9 6 2 0 * 0610/43 BIOLOGY May/June 2018 Paper 4 Theory (Extended) 1 hour 15 minutes Candidates answer on the Question Paper. No Additional Materials are required. READ THESE INSTRUCTIONS FIRST Write your Centre number, candidate number and name on all the work you hand in. Write in dark blue or black pen. You may use an HB pencil for any diagrams or graphs. Do not use staples, paper clips, glue or correction fluid. DO NOT WRITE IN ANY BARCODES. Answer all questions. Electronic calculators may be used. You may lose marks if you do not show your working or if you do not use appropriate units. At the end of the examination, fasten all your work securely together. The number of marks is given in brackets [ ] at the end of each question or part question. This syllabus is approved for use in England, Wales and Northern Ireland as a Cambridge International Level 1/Level 2 Certificate. This document consists of 17 printed pages and 3 blank pages. DC (LEG/SW) 145575/4 © UCLES 2018 [Turn over www.dynamicpapers.com 2 1 Two functions of the alimentary canal are mechanical digestion and chemical digestion. (a) Outline where and how mechanical digestion occurs in the alimentary canal. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[4] (b) Enzymes catalyse the reactions of chemical digestion. Table 1.1 gives information about chemical digestion in three parts of the alimentary canal. Complete Table 1.1. Table 1.1 part of the alimentary canal mouth enzyme substrate product(s) starch stomach peptides fat fatty acids and glycerol [3] © UCLES 2018 0610/43/M/J/18 3 www.dynamicpapers.com (c) Substances that are absorbed from the alimentary canal may enter cells and become part of the cells. (i) State the storage carbohydrate made from glucose in liver cells. .......................................................................................................................................[1] (ii) State the type of protein used in the immune system that is produced from amino acids by lymphocytes. .......................................................................................................................................[1] (iii) Fat is produced from fatty acids and glycerol by cells in the fatty tissue beneath the skin. State one function of this layer of fat. .......................................................................................................................................[1] [Total: 10] © UCLES 2018 0610/43/M/J/18 [Turn over 4 2 www.dynamicpapers.com Fig. 2.1 shows an Arctic wolf, Canis lupus. These wolves are one of the few mammals adapted to the extreme cold of the tundra in the Canadian Arctic and in Alaska. Fig. 2.1 (a) (i) State two features, visible in Fig. 2.1, that identify Arctic wolves as mammals. 1 ........................................................................................................................................ 2 ........................................................................................................................................ [2] (ii) Arctic wolves show many adaptive features to a cold environment. Explain what is meant by the term adaptive feature. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[3] © UCLES 2018 0610/43/M/J/18 5 www.dynamicpapers.com (b) The food available to animals in the Arctic tundra is limited. There is a short growing season for plants and the environmental conditions do not favour high rates of photosynthesis and growth compared with temperate and tropical ecosystems. State three conditions that limit plant growth rates. 1 ................................................................................................................................................ 2 ................................................................................................................................................ 3 ................................................................................................................................................ [3] (c) Arctic wolves are the top carnivores in the food web in the tundra. Explain why the number of Arctic wolves is so small in this ecosystem. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[6] [Total: 14] © UCLES 2018 0610/43/M/J/18 [Turn over 6 3 www.dynamicpapers.com Fig. 3.1 is a scanning electron micrograph of a vertical section through part of the leaf of a broad bean plant, Vicia faba. A B air spaces C Fig. 3.1 (a) (i) State the names of the tissues labelled A and B. A ........................................................................................................................................ B ........................................................................................................................................ [2] (ii) The cells in regions B and C in Fig. 3.1 have a large surface area. Explain why this is necessary for the functioning of the leaf cells. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[3] (iii) Explain why there are many interconnecting air spaces within the leaf. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[2] © UCLES 2018 0610/43/M/J/18 7 www.dynamicpapers.com (b) When water is in short supply, plants can wilt as shown in Fig. 3.2. Fig. 3.2 (i) State two conditions that are likely to increase the chances of wilting. 1 ........................................................................................................................................ 2 ........................................................................................................................................ [2] (ii) Explain what happens to the cells of a leaf to cause wilting. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[4] © UCLES 2018 0610/43/M/J/18 [Turn over 8 (iii) www.dynamicpapers.com Wilting may look harmful, but it is often a strategy for survival. Suggest the advantages to a plant of wilting. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[2] [Total: 15] © UCLES 2018 0610/43/M/J/18 9 www.dynamicpapers.com BLANK PAGE © UCLES 2018 0610/43/M/J/18 [Turn over 10 4 www.dynamicpapers.com (a) The endocrine system in mammals produces hormones. Define the term hormone. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[2] (b) The responses of the human body to danger are coordinated by the nervous and endocrine systems. Fig. 4.1 shows the sequence of events that occurs in response to a dangerous situation that is detected by the eyes. P Q Key: nerve impulses hormone Fig. 4.1 © UCLES 2018 0610/43/M/J/18 11 (i) www.dynamicpapers.com State the tissue in the eye that converts light energy into nerve impulses. .......................................................................................................................................[1] (ii) State the part of the eye that has the highest concentration of light-sensitive cells and gives the most detailed image. .......................................................................................................................................[1] (iii) State the type of neurone that conducts impulses from the eye to the brain. .......................................................................................................................................[1] (iv) State the nerve that contains these neurones that conduct impulses from the eye to the brain. .......................................................................................................................................[1] (v) Identify the organ labelled P. .......................................................................................................................................[1] (vi) Identify the gland labelled Q. .......................................................................................................................................[1] (c) Complete Table 4.1 to describe the effects of the hormone released when a person is in a dangerous situation. Table 4.1 organ effect of the hormone heart liver lungs eyes [4] © UCLES 2018 0610/43/M/J/18 [Turn over 12 www.dynamicpapers.com (d) Explain the advantages of coordinating the response to a dangerous situation using both the nervous system and the endocrine system. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[4] (e) (i) Plants also make hormones. State the name of one hormone made by plants. .......................................................................................................................................[1] (ii) Some plant hormones are manufactured and applied to crops to alter aspects of plant growth. Describe how the synthetic plant hormone 2,4-D is used in agriculture. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[2] [Total: 19] © UCLES 2018 0610/43/M/J/18 13 5 www.dynamicpapers.com (a) State the balanced chemical equation for aerobic respiration. ...............................................................................................................................................[2] (b) Students investigated the rate of respiration of crickets (a type of insect) using a carbon dioxide sensor and laptop as shown in Fig. 5.1. The sensor was fitted inside an airtight glass jar. The apparatus was set up in a room with a constant temperature of 17 °C. Fig. 5.1 The students found that the concentration of carbon dioxide inside the jar increased by 50 ppm in 120 seconds. Calculate the rate of carbon dioxide production as ppm per second. Show your working and express your answer to two significant figures. ............................................ ppm s–1 [1] © UCLES 2018 0610/43/M/J/18 [Turn over 14 www.dynamicpapers.com (c) After 10 minutes, the students opened the jar by removing the sensor. They left the jar open for 5 minutes but made sure that the crickets remained in the jar. They then replaced the sensor and took more readings for another 10 minutes. State and explain one reason for opening the jar after 10 minutes. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[2] (d) During the investigation the temperature inside the jar increased. The temperature outside the jar remained constant. Explain why the temperature inside the jar increased. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[2] © UCLES 2018 0610/43/M/J/18 www.dynamicpapers.com 15 (e) Researchers in Chile also investigated the rate of respiration in crickets. They investigated the effect of temperature and body mass on the rate of respiration. They measured the rate of oxygen consumption in crickets with different body masses, at different temperatures. The researchers’ results are shown in Fig. 5.2. 30 27 °C 25 rate of oxygen consumption / 10–3 cm3 h–1 20 17 °C 15 10 7 °C 5 0 0 10 20 30 40 50 body mass / mg 60 70 80 Fig. 5.2 State two conclusions that can be made from the data in Fig. 5.2 and support each conclusion with evidence from the graph. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[4] [Total:11] © UCLES 2018 0610/43/M/J/18 [Turn over www.dynamicpapers.com 16 6 (a) Fig. 6.1 is a half-flower drawing of pride of Barbados, Caesalpinia pulcherrima. D C B E F A Fig. 6.1 Complete Table 6.1 by stating the letter from Fig. 6.1 that indicates the organ where each function occurs and the name of the organ. Table 6.1 function letter from Fig. 6.1 name of the organ meiosis to produce pollen grains pollination development of seeds protection of flower in the bud [4] © UCLES 2018 0610/43/M/J/18 www.dynamicpapers.com 17 (b) Fig. 6.2 is a scanning electron micrograph of some pollen grains from wind-pollinated flowers and insect-pollinated flowers. H J magnification ×220 Fig. 6.2 (i) Write the formula that would be used to calculate the actual diameter of pollen grain H. [1] (ii) The actual diameter of pollen grain H is 0.082 mm. Convert this value to micrometres (μm). Space for working. ..................................................... μm [1] (iii) Explain how the pollen grain labelled J is adapted for insect pollination. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[2] © UCLES 2018 0610/43/M/J/18 [Turn over 18 www.dynamicpapers.com (c) Pollen grains grow tubes, which contain haploid male gamete nuclei. (i) One of these male gamete nuclei fuses with the female gamete. State the part of the flower that contains the female gamete. .......................................................................................................................................[1] (ii) Define the term haploid nucleus. ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[1] (iii) Explain why it is important for gametes to be haploid. ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[1] [Total: 11] © UCLES 2018 0610/43/M/J/18 19 BLANK PAGE © UCLES 2018 0610/43/M/J/18 www.dynamicpapers.com 20 www.dynamicpapers.com BLANK PAGE Permission to reproduce items where third-party owned material protected by copyright is included has been sought and cleared where possible. Every reasonable effort has been made by the publisher (UCLES) to trace copyright holders, but if any items requiring clearance have unwittingly been included, the publisher will be pleased to make amends at the earliest possible opportunity. To avoid the issue of disclosure of answer-related information to candidates, all copyright acknowledgements are reproduced online in the Cambridge International Examinations Copyright Acknowledgements Booklet. This is produced for each series of examinations and is freely available to download at www.cie.org.uk after the live examination series. Cambridge International Examinations is part of the Cambridge Assessment Group. Cambridge Assessment is the brand name of University of Cambridge Local Examinations Syndicate (UCLES), which is itself a department of the University of Cambridge. © UCLES 2018 0610/43/M/J/18 Cambridge International Examinations Cambridge International General Certificate of Secondary Education * 2 2 0 3 4 7 9 9 5 2 * 0610/41 BIOLOGY October/November 2018 Paper 4 Theory (Extended) 1 hour 15 minutes Candidates answer on the Question Paper. No Additional Materials are required. READ THESE INSTRUCTIONS FIRST Write your Centre number, candidate number and name on all the work you hand in. Write in dark blue or black pen. You may use an HB pencil for any diagrams or graphs. Do not use staples, paper clips, glue or correction fluid. DO NOT WRITE IN ANY BARCODES. Answer all questions. Electronic calculators may be used. You may lose marks if you do not show your working or if you do not use appropriate units. At the end of the examination, fasten all your work securely together. The number of marks is given in brackets [ ] at the end of each question or part question. This syllabus is approved for use in England, Wales and Northern Ireland as a Cambridge International Level 1/Level 2 Certificate. This document consists of 16 printed pages. DC (ST/JG) 152888/3 © UCLES 2018 [Turn over 2 1 Fig. 1.1 shows a pyramid of biomass and part of the carbon cycle. CO2 in atmosphere X A decomposers B C D fossil fuels Fig. 1.1 (a) (i) State the principal source of energy required for trophic level D of the pyramid of biomass in Fig. 1.1. .......................................................................................................................................[1] (ii) State the letter that represents the primary consumers in Fig. 1.1. ........................................... (iii) [1] State how carbon is transferred from producers to primary consumers. .......................................................................................................................................[1] (iv) Explain why trophic level A is smaller than trophic level B in the pyramid of biomass in Fig. 1.1. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[3] © UCLES 2018 0610/41/O/N/18 3 (b) Some fungi and bacteria are decomposers. (i) Define the term decomposer. ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[1] (ii) Arrow X on Fig. 1.1 indicates the transfer of carbon from decomposers to the atmosphere. State the name of process X. .......................................................................................................................................[1] (c) Describe how human activities are affecting the carbon cycle. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[5] [Total: 13] © UCLES 2018 0610/41/O/N/18 [Turn over 4 2 Microbiologists test strains of bacteria for antibiotic resistance. They do this by soaking paper discs in antibiotics and placing them on bacteria growing in Petri dishes. The paper discs in the centre of Petri dishes E and F in Fig. 2.1 have been soaked in penicillin. zone where bacteria are growing paper disc soaked in penicillin E F zone where bacteria are no longer growing Fig. 2.1 (a) State the type of microorganism that produces penicillin. ...............................................................................................................................................[1] (b) State and explain the evidence from Fig. 2.1 that suggests that the bacteria in dish F are resistant to penicillin. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[2] © UCLES 2018 0610/41/O/N/18 5 (c) (i) Explain how bacteria become resistant to antibiotics and how humans can reduce the problem of antibiotic resistance. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[6] (ii) Explain why viral infections cannot be treated with antibiotics. ........................................................................................................................................... .......................................................................................................................................[1] (d) Some bacteria and viruses cause disease but many are useful to the biotechnology industry. Explain why bacteria are useful in biotechnology. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[3] [Total: 13] © UCLES 2018 0610/41/O/N/18 [Turn over 6 3 Fig. 3.1 shows a photomicrograph of a section of a root. J K L M Fig. 3.1 (a) Structure J is a xylem vessel. The xylem vessels conduct water from the roots to the stems. State the features of xylem vessels that enable them to conduct water. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[3] © UCLES 2018 0610/41/O/N/18 7 (b) Describe the pathway of water from outside the root to the xylem vessels (J) at the centre of the root. Use the letters in Fig. 3.1 in your answer. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[5] © UCLES 2018 0610/41/O/N/18 [Turn over 8 (c) Scientists wanted to determine the flow-rate of water in roots. They measured the flow-rate in three zones of onion roots as shown in Fig. 3.2. zone 3 glass jar containing water zone 2 zone 1 Fig. 3.2 They measured the flow-rate in healthy roots and roots that had been treated with a toxic solution. Their results are shown in Table 3.1. Table 3.1 zone in Fig. 3.2 (i) average flow-rate of water / arbitrary units healthy roots treated roots 1 150 160 2 230 200 3 280 270 Calculate the percentage increase in the average flow-rate between zone 1 and 3 for healthy roots. Give your answer to two significant figures. Show your working. © UCLES 2018 0610/41/O/N/18 ............................................................ % [2] 9 (ii) The scientists observed that the xylem vessels nearer the root tip were narrower than the xylem vessels higher up the root. Describe how the width of xylem vessels in different zones of a root affects the average flow-rate of water. Use the information in Table 3.1 in your answer. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[3] (iii) Suggest why there was little difference in the flow-rate in healthy roots and in roots treated with the toxic solution. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[2] [Total: 15] © UCLES 2018 0610/41/O/N/18 [Turn over 10 4 The eye is a sense organ that responds to light. Fig. 4.1 is a diagram of a section through the human eye. Q R W S X T Y U Fig. 4.1 (a) Table 4.1 describes some of the functions of the parts of the eye. Complete the table by: • • naming the parts of the eye using the letters on Fig. 4.1 to identify the parts of the eye. Table 4.1 function name of part letter on Fig. 4.1 carries impulses to the brain focuses light onto the back of the eye controls the tension of the suspensory ligaments tissue that detects light and colour location of most of the cone cells [5] © UCLES 2018 0610/41/O/N/18 11 (b) (i) A pair of muscles in the eye work in opposition to each other to adjust the amount of light entering the pupil. State the term that describes the action of a pair of muscles working in opposition to each other. .......................................................................................................................................[1] (ii) A different pair of muscles in the eye work in opposition to each other to view objects at different distances from the eye. State the name of the process that allows the eye to view objects at different distances. .......................................................................................................................................[1] (c) Explain why the eye cannot easily identify different colours in low levels of light. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[2] (d) Some people inherit colour blindness and cannot identify certain colours, even in bright light. The gene responsible for colour vision is located on the X chromosome. There are two alleles for this gene on the X chromosome: • • (i) XB – normal colour vision Xb – colour blindness. People that are heterozygous for colour blindness are called carriers. State the genotype of a heterozygous female carrier. .......................................................................................................................................[1] (ii) There is no gene for colour vision on the male sex chromosome. State the genotype of a colour-blind male. .......................................................................................................................................[1] © UCLES 2018 0610/41/O/N/18 [Turn over 12 Fig. 4.2 shows a pedigree diagram for colour blindness. 1 2 Key: colour vision female 3 9 10 4 5 11 12 6 7 8 13........... carrier female colour-blind female colour vision male carrier male colour-blind male Fig. 4.2 (iii) Person 13 in Fig. 4.2 is male. His parents are person 7 and person 8. Use the key to complete Fig. 4.2 by drawing the correct symbol for person 13. (iv) [1] Colour blindness is a sex-linked characteristic. Explain why females 4 and 5 are carriers even though their mother is not a carrier. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[2] [Total: 14] © UCLES 2018 0610/41/O/N/18 13 5 The liver is an important organ in many processes. (a) The liver responds to changes in insulin concentration. Insulin is a hormone. (i) Define the term hormone. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[3] (ii) Describe how the liver responds to an increase in insulin concentration. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[2] (b) The liver is also involved in the processing of amino acids. (i) Describe how excess amino acids are broken down. ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[2] (ii) State the name of the process that assembles amino acids to form proteins. .......................................................................................................................................[1] © UCLES 2018 0610/41/O/N/18 [Turn over 14 (c) The liver is also involved in the processing of toxins. (i) Lactic acid is an example of a toxin that is produced during vigorous exercise and processed in the liver. Describe how lactic acid is processed. ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[2] (ii) Alcohol is another toxin that is processed in the liver. The effect of alcohol consumption on the risk of dying from liver disease was investigated in men and women. The results are shown in Fig. 5.1. Key: 60 50 men women 40 risk of dying from liver 30 disease / arbitrary 20 units 10 0 0 20 40 60 80 100 120 140 160 alcohol consumption / g per day Fig. 5.1 Describe the results shown in Fig. 5.1. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[4] [Total: 14] © UCLES 2018 0610/41/O/N/18 15 6 Young mammals that are orphaned can be bottle-fed. Fig. 6.1 shows a newborn tiger cub sucking on a bottle. Fig. 6.1 (a) (i) Sucking is an example of an involuntary action observed in newborn mammals. State the name given to involuntary actions. .......................................................................................................................................[1] (ii) Describe the advantages of breast-feeding compared with bottle-feeding. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[4] © UCLES 2018 0610/41/O/N/18 [Turn over 16 (b) The digestive systems of young mammals are not fully developed. Enzymes such as amylase, maltase and protease are often added to baby food to aid chemical digestion. (i) Complete Table 6.1 by stating the substrate and product(s) for each enzyme reaction. Table 6.1 enzyme substrate product(s) amylase maltase protease [3] (ii) Suggest why the temperature of baby food must be controlled when the enzymes are added. ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[2] (iii) State one other condition that must also be controlled to optimise enzyme activity. .......................................................................................................................................[1] [Total: 11] Permission to reproduce items where third-party owned material protected by copyright is included has been sought and cleared where possible. Every reasonable effort has been made by the publisher (UCLES) to trace copyright holders, but if any items requiring clearance have unwittingly been included, the publisher will be pleased to make amends at the earliest possible opportunity. To avoid the issue of disclosure of answer-related information to candidates, all copyright acknowledgements are reproduced online in the Cambridge International Examinations Copyright Acknowledgements Booklet. This is produced for each series of examinations and is freely available to download at www.cie.org.uk after the live examination series. Cambridge International Examinations is part of the Cambridge Assessment Group. Cambridge Assessment is the brand name of University of Cambridge Local Examinations Syndicate (UCLES), which is itself a department of the University of Cambridge. © UCLES 2018 0610/41/O/N/18 Cambridge International Examinations Cambridge International General Certificate of Secondary Education * 3 5 8 0 8 4 5 9 9 9 * 0610/42 BIOLOGY Paper 4 Theory (Extended) October/November 2018 1 hour 15 minutes Candidates answer on the Question Paper. No Additional Materials are required. READ THESE INSTRUCTIONS FIRST Write your Centre number, candidate number and name on all the work you hand in. Write in dark blue or black pen. You may use a pencil for any diagrams or graphs. Do not use staples, paper clips, glue or correction fluid. DO NOT WRITE IN ANY BARCODES. Answer all questions. Electronic calculators may be used. You may lose marks if you do not show your working or if you do not use appropriate units. At the end of the examination, fasten all your work securely together. The number of marks is given in brackets [ ] at the end of each question or part question. This syllabus is approved for use in England, Wales and Northern Ireland as a Cambridge International Level 1/Level 2 Certificate. This document consists of 18 printed pages and 2 blank pages. DC (NF/CT) 152730/3 © UCLES 2018 [Turn over 2 BLANK PAGE © UCLES 2018 0610/42/O/N/18 3 1 Wetlands are important ecosystems. Researchers studied the feeding relationships between the organisms in an area of wetland on the coast of Texas. Fig. 1.1 shows part of the food web that they studied. spotted sandpiper bald eagle stone crab marsh rice rat blenny mycid shrimp snow goose oyster water flea pipe fish muskrat clover algae and phytoplankton grass Fig. 1.1 (a) Complete Table 1.1 by giving the name of one organism from the food web in Fig. 1.1 for each row. Table 1.1 name of organism from Fig. 1.1 producer secondary consumer an animal that feeds at two trophic levels [3] © UCLES 2018 0610/42/O/N/18 [Turn over 4 The functioning of ecosystems relies on the cycling of nutrients. Fig. 1.2 shows part of the nitrogen cycle. nitrogen gas in the air B amino acids in plants plants D proteins in plants C nitrate ions A proteins in dead plants ammonium ions Fig. 1.2 (b) State the name of process A in Fig. 1.2 and give the type of organism that converts ammonium ions to nitrate ions. A ............................................................................................................................................... type of organism ....................................................................................................................... [2] (c) Describe how nitrate ions enter the roots of plants shown by arrow C on Fig. 1.2. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... .............................................................................................................................................. [3] © UCLES 2018 0610/42/O/N/18 5 (d) State the name of the structure in plant cells where process D occurs. .............................................................................................................................................. [1] (e) State the process that occurs at B. .............................................................................................................................................. [1] (f) A pyramid of numbers for the wetland ecosystem showed that there were very large numbers of organisms at the base of the pyramid and very few at the top. Explain why. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... .............................................................................................................................................. [3] [Total: 13] © UCLES 2018 0610/42/O/N/18 [Turn over 6 BLANK PAGE © UCLES 2018 0610/42/O/N/18 7 2 Fig. 2.1 shows a dwarf sunflower and a tall sunflower, Helianthus annuus. The height of the dwarf sunflower is 0.45 m and the height of the tall sunflower is 4.5 m. dwarf tall not to scale Fig. 2.1 Dwarf plants like the one in Fig. 2.1 have mutant alleles. (a) Define the term allele. ................................................................................................................................................... .............................................................................................................................................. [1] (b) Shoot growth in plants is controlled by auxins. An enzyme in shoot tips converts molecules of an amino acid into auxins as shown in Fig. 2.2. amino acid enzyme auxin Fig. 2.2 Explain how a mutation in DNA results in an abnormal enzyme which does not catalyse the reaction shown in Fig. 2.2. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... .............................................................................................................................................. [3] © UCLES 2018 0610/42/O/N/18 [Turn over 8 (c) Two tall sunflower plants were crossed. 25% of the offspring produced were dwarf. Explain how it is possible for two tall parent plants to have this percentage of dwarf offspring. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... .............................................................................................................................................. [2] (d) Fig. 2.3 shows how several strawberry plants can be formed from one parent plant. parent plant offspring Fig. 2.3 (i) Explain the type of reproduction that produces plants by the method shown in Fig. 2.3. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ...................................................................................................................................... [3] © UCLES 2018 0610/42/O/N/18 9 (ii) Explain the disadvantages of the type of reproduction shown in Fig. 2.3. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ...................................................................................................................................... [3] [Total: 12] © UCLES 2018 0610/42/O/N/18 [Turn over 10 3 (a) Fig. 3.1 is a photomicrograph of some xylem vessels. Fig. 3.1 (i) State one structural feature of xylem vessels and explain how this is related to the function of water transport. feature ............................................................................................................................... ........................................................................................................................................... explanation ........................................................................................................................ ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... [2] (ii) Explain the mechanism that is responsible for the movement of water in xylem vessels. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ...................................................................................................................................... [4] © UCLES 2018 0610/42/O/N/18 11 (iii) State one role of xylem vessels other than transport. ...................................................................................................................................... [1] (b) The rate of transpiration is affected by several factors including the temperature and the humidity of the air. State and explain the effect of an increase in temperature on the rate of transpiration. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... .............................................................................................................................................. [3] [Total: 10] © UCLES 2018 0610/42/O/N/18 [Turn over 12 4 Insulin is a hormone that regulates the concentration of glucose in the blood. (a) Define the term hormone. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... .............................................................................................................................................. [3] (b) Two people, A and B, visited a doctor to discuss their similar symptoms. The doctor thought that their blood glucose concentrations were not very well controlled. A glucose tolerance test was carried out on both people. A and B did not eat or drink anything other than water for eight hours before the test. They then drank a glucose solution. Blood samples were taken at 30 minute intervals. The samples were tested for glucose concentration. The results are shown in Fig. 4.1. blood glucose concentration / mg per 100 cm3 220 200 A 180 160 glucose solution taken 140 120 100 B 80 60 40 20 0 0 30 60 90 120 time / minutes Fig. 4.1 © UCLES 2018 0610/42/O/N/18 150 180 210 240 13 (i) Use Fig. 4.1 to state the blood glucose concentrations of A and B at 180 minutes. A .............................................................................................................. mg per 100 cm3 B .............................................................................................................. mg per 100 cm3 [1] (ii) Calculate the percentage increase in the blood glucose concentration in person A between 60 and 90 minutes. Give your answer to the nearest whole number. Show your working. ................ % [2] (iii) Describe how the response of person A differs from the response of person B in Fig. 4.1. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ...................................................................................................................................... [2] (iv) Explain the results of the glucose tolerance test shown by person B. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ...................................................................................................................................... [4] © UCLES 2018 0610/42/O/N/18 [Turn over 14 (v) The doctor thought that person A had Type 1 diabetes. Describe three symptoms of Type 1 diabetes. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ...................................................................................................................................... [3] [Total: 15] © UCLES 2018 0610/42/O/N/18 15 5 Fig. 5.1 shows a photomicrograph of human blood. phagocyte lymphocyte red blood cell Fig. 5.1 (a) Describe the differences in appearance and the roles of the three cells labelled in Fig. 5.1. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... .............................................................................................................................................. [6] © UCLES 2018 0610/42/O/N/18 [Turn over 16 (b) Fig. 5.2 shows some of the stages of blood clotting. a blood vessel breaks platelets collect at the break in the blood vessel platelets release an enzyme thrombin prothrombin forms a mesh at the break in the blood vessel Fig. 5.2 (i) Complete Fig. 5.2 by filling in the two empty boxes. (ii) State two roles of blood clotting. [1] ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ...................................................................................................................................... [2] © UCLES 2018 0610/42/O/N/18 17 (c) Haemophilia is a sex-linked blood disorder in which blood takes a long time to clot. Fig. 5.3 is a pedigree diagram showing the inheritance of haemophilia. P Q R S T male with normal clotting time male with haemophilia female with normal clotting time Fig. 5.3 The normal allele is represented by XH and the mutant allele is represented by Xh. (i) State the genotypes of the people identified as P, Q and R in Fig. 5.3. P ........................................................................................................................................ Q ....................................................................................................................................... R ........................................................................................................................................ [3] © UCLES 2018 0610/42/O/N/18 [Turn over 18 (ii) The couple S and T are expecting another child. What is the probability that the child will have haemophilia? Space for working ...................................................................................................................................... [1] (iii) Define the term sex-linked characteristic. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ...................................................................................................................................... [2] [Total: 15] © UCLES 2018 0610/42/O/N/18 19 6 Fig. 6.1 shows the Galapagos iguana, Amblyrhynchus cristatus. Fig. 6.1 (a) (i) State two features that are used to classify animals, such as the Galapagos iguana, as reptiles. 1 ........................................................................................................................................ 2 ........................................................................................................................................ [2] (ii) State two features that are present in plant cells that are not present in the cells of reptiles. 1 ........................................................................................................................................ 2 ........................................................................................................................................ [2] (b) Galapagos iguanas feed on seaweed which contains starch and other carbohydrates. (i) State the name of the enzyme that digests starch. ...................................................................................................................................... [1] (ii) State the names of two parts of the alimentary canal where starch is digested. 1 ........................................................................................................................................ 2 ........................................................................................................................................ [2] © UCLES 2018 0610/42/O/N/18 [Turn over 20 (c) There are many threats to wildlife in the Galapagos. Describe ways in which endangered species can be conserved. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... .............................................................................................................................................. [5] (d) One aim of conservation is to maintain resources in natural ecosystems. State three resources that natural ecosystems provide for humans. 1 ................................................................................................................................................ 2 ................................................................................................................................................ 3 ................................................................................................................................................ [3] [Total: 15] Permission to reproduce items where third-party owned material protected by copyright is included has been sought and cleared where possible. Every reasonable effort has been made by the publisher (UCLES) to trace copyright holders, but if any items requiring clearance have unwittingly been included, the publisher will be pleased to make amends at the earliest possible opportunity. To avoid the issue of disclosure of answer-related information to candidates, all copyright acknowledgements are reproduced online in the Cambridge International Examinations Copyright Acknowledgements Booklet. This is produced for each series of examinations and is freely available to download at www.cie.org.uk after the live examination series. Cambridge International Examinations is part of the Cambridge Assessment Group. Cambridge Assessment is the brand name of University of Cambridge Local Examinations Syndicate (UCLES), which is itself a department of the University of Cambridge. © UCLES 2018 0610/42/O/N/18 Cambridge International Examinations Cambridge International General Certificate of Secondary Education * 2 4 8 0 3 9 0 3 5 7 * 0610/43 BIOLOGY Paper 4 Theory (Extended) October/November 2018 1 hour 15 minutes Candidates answer on the Question Paper. No Additional Materials are required. READ THESE INSTRUCTIONS FIRST Write your Centre number, candidate number and name on all the work you hand in. Write in dark blue or black pen. You may use an HB pencil for any diagrams or graphs. Do not use staples, paper clips, glue or correction fluid. DO NOT WRITE IN ANY BARCODES. Answer all questions. Electronic calculators may be used. You may lose marks if you do not show your working or if you do not use appropriate units. At the end of the examination, fasten all your work securely together. The number of marks is given in brackets [ ] at the end of each question or part question. This syllabus is approved for use in England, Wales and Northern Ireland as a Cambridge International Level 1/Level 2 Certificate. This document consists of 17 printed pages and 3 blank pages. DC (CE/SW) 152729/4 © UCLES 2018 [Turn over 2 1 Water is a very important molecule for all living organisms. (a) (i) State the name of the organ in plants where most water is absorbed. .......................................................................................................................................[1] (ii) State the name of the organ in humans where most water is absorbed. .......................................................................................................................................[1] (iii) State one property of water that makes it useful to animals and plants. .......................................................................................................................................[1] (b) The flow diagram in Fig. 1.1 shows a town and part of the water cycle. P Q H F K G J Fig. 1.1 © UCLES 2018 0610/43/O/N/18 L M N O 3 Table 1.1 describes some of the processes in the water cycle. Complete Table 1.1. One row has been done for you. Table 1.1 description name of the process letter in Fig. 1.1 leaching F nitrate ions are washed into rivers an algal bloom in the water is caused by leaching of nitrate ions evaporation conversion of water from a vapour to a liquid transpiration [4] (c) Polluted water can be purified at a sewage treatment works. (i) State one reason why it is necessary to treat polluted water before it is used as drinking water. ........................................................................................................................................... .......................................................................................................................................[1] (ii) Outline the process of sewage treatment. You may use the letters in Fig. 1.1 in your answer. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[4] [Total: 12] © UCLES 2018 0610/43/O/N/18 [Turn over 4 2 The Indian muntjac deer, Muntiacus muntjak, is recorded as the mammal with the lowest number of chromosomes. Fig. 2.1 is an image of the chromosomes in the nucleus of a diploid cell of a female muntjac deer. sex chromosomes Fig. 2.1 (a) State the diploid number of chromosomes for the female muntjac deer. ................................................................... [1] (b) Fig. 2.2 is an image of the chromosomes in the nucleus of a diploid cell of a male muntjac deer. sex chromosomes Fig. 2.2 Describe how the sex chromosomes of the male muntjac deer shown in Fig. 2.2 differ from those of the female shown in Fig. 2.1. ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[2] © UCLES 2018 0610/43/O/N/18 5 (c) Explain how meiosis can result in variation in a species. Use the words chromosome and gametes in your answer. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[4] (d) Another cause of variation is the formation of new alleles. Describe how new alleles can be formed. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[3] [Total: 10] © UCLES 2018 0610/43/O/N/18 [Turn over 6 BLANK PAGE © UCLES 2018 0610/43/O/N/18 7 3 (a) Fig. 3.1 is a photomicrograph of part of the upper surface of a broad bean leaf, Vicia faba. P Fig. 3.1 (i) On Fig. 3.1, identify and label two structures that are visible in cell P. (ii) State the name of the tissue shown in Fig. 3.1. [2] .......................................................................................................................................[1] (iii) The tissue shown in Fig. 3.1 is transparent. Explain why it is important to the plant that the tissue shown in Fig. 3.1 is transparent. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[3] © UCLES 2018 0610/43/O/N/18 [Turn over 8 (b) Stomata are found on the lower surface of broad bean leaves. Describe the function of stomata. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[3] (c) More than 40 years ago, botanists studied the leaves of broad bean plants and discovered that guard cells control the opening and closing of stomata. They found that stomata were open when the guard cells were turgid. Table 3.1 shows some of their measurements. Table 3.1 closed stomata ion concentration in guard cells / pmol 0.3 2.5 4000.0 6500.0 turgor pressure in the guard cells / MPa 2.0 4.8 width of stomatal opening / μm 0.0 8.0 guard cell volume / μm3 (i) open stomata Ions move into guard cells by active transport. Describe how the ions move into the guard cells. ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[2] © UCLES 2018 0610/43/O/N/18 9 (ii) Describe and explain how the change in ion concentration causes the guard cell volume to change. Use the information in Table 3.1 in your answer. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[5] (iii) The botanists left the broad bean plants unattended for three days. During this time the broad bean plants wilted. Suggest two environmental factors that can cause plants to wilt. 1 ........................................................................................................................................ 2 ........................................................................................................................................ [2] [Total: 18] © UCLES 2018 0610/43/O/N/18 [Turn over 10 BLANK PAGE © UCLES 2018 0610/43/O/N/18 11 4 Glycogen is a storage carbohydrate in animals. Glycogen is made from glucose. (a) (i) Cells that convert glucose to glycogen contain many mitochondria. Suggest why these cells contain many mitochondria. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[2] (ii) State the type of biological molecule that catalyses reactions such as the conversion of glycogen to glucose. .......................................................................................................................................[1] (b) A fetus needs glucose to make glycogen. Describe how a fetus obtains glucose. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[3] © UCLES 2018 0610/43/O/N/18 [Turn over 12 (c) Fig. 4. 1 shows the concentration of glycogen in the fetus of a domestic cat during pregnancy and immediately after birth. birth 700 600 500 glycogen concentration 400 / μmol per g 300 200 100 0 0 10 20 30 40 50 60 70 time since fertilisation / days 80 90 Fig. 4.1 Hormones stimulate changes in the concentration of glycogen in the fetus. (i) Define the term hormone. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[3] © UCLES 2018 0610/43/O/N/18 13 (ii) Calculate the percentage increase in the glycogen concentration in the fetus between day 10 and birth in Fig. 4.1. Give your answer to the nearest whole number. Show your working. ............................................................ % [2] (iii) Describe the changes in glycogen concentration shown in Fig. 4.1 and explain how hormones in the fetus cause these changes. Use data from Fig. 4.1 to support your answer. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[6] © UCLES 2018 0610/43/O/N/18 [Turn over 14 (d) After birth, cats produce milk to feed their offspring. Human babies can be breast-fed or bottle-fed with formula milk. Outline three disadvantages of breast-feeding. 1 ................................................................................................................................................ ................................................................................................................................................... 2 ................................................................................................................................................ ................................................................................................................................................... 3 ................................................................................................................................................ ................................................................................................................................................... [3] [Total: 20] © UCLES 2018 0610/43/O/N/18 15 5 An ecologist studied variation in a species of xerophyte. (a) Xerophytes are adapted to a particular type of environment. State this type of environment. ...............................................................................................................................................[1] (b) The ecologist studied the features of the leaves in the species of xerophyte. Fig. 5.1 shows the variation in the type of leaf spike. 9 8 7 6 number of individuals 5 4 3 2 1 0 type 1 type 2 type of leaf spike type 3 Fig. 5.1 (i) State the type of variation shown in Fig. 5.1. .......................................................................................................................................[1] (ii) Explain why the type of leaf spike is an example of the variation shown in Fig. 5.1. ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[2] © UCLES 2018 0610/43/O/N/18 [Turn over 16 (c) The ecologist also measured other features of the leaves. Fig. 5.2 shows the variation in leaf feature B. 9 8 7 6 number of individuals 5 4 3 2 1 0 0–5 6–10 11–15 16–20 21–25 leaf feature B / arbitrary units Fig. 5.2 State two named features of leaves that show the type of variation shown in Fig. 5.2. 1 ................................................................................................................................................ 2 ................................................................................................................................................ [2] © UCLES 2018 0610/43/O/N/18 17 (d) After one year, the ecologist recorded the variation in leaf feature B again. The results are shown in Fig. 5.3. 9 8 7 6 number of individuals 5 4 3 2 1 0 0–5 6–10 11–15 16–20 21–25 leaf feature B / arbitrary units Fig. 5.3 Suggest one reason for the difference in variation of leaf feature B after one year. ................................................................................................................................................... ...............................................................................................................................................[1] [Total: 7] © UCLES 2018 0610/43/O/N/18 [Turn over 18 6 Fig. 6.1 is a diagram showing some body cells and parts of the human lymphatic and circulatory systems. arteriole X lymphatic vessel B A capillary Z Y venule not to scale Fig. 6.1 (a) Capillaries allow blood to reach most cells in the body. (i) State the name of the process by which oxygen moves from A to Z as shown in Fig. 6.1. .......................................................................................................................................[1] (ii) Describe how some of the liquid in A moves to B in Fig. 6.1. ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[2] (iii) State one component of blood that remains inside the capillaries as the blood flows from X to Y in Fig. 6.1. .......................................................................................................................................[1] © UCLES 2018 0610/43/O/N/18 19 (b) Lymphatic vessels are similar in structure to veins. (i) Describe the structure of veins. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[2] (ii) Describe the role of the lymphatic vessel shown in Fig. 6.1. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[2] (c) Lacteals are another part of the lymphatic system. State where in the body lacteals are found and state their function. location in the body ................................................................................................................... function ..................................................................................................................................... ................................................................................................................................................... [2] (d) In the lymphatic system, there are structures that contain large numbers of lymphocytes. (i) State the name of these structures. .......................................................................................................................................[1] (ii) State the role of lymphocytes. ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[2] [Total: 13] © UCLES 2018 0610/43/O/N/18 20 BLANK PAGE Permission to reproduce items where third-party owned material protected by copyright is included has been sought and cleared where possible. Every reasonable effort has been made by the publisher (UCLES) to trace copyright holders, but if any items requiring clearance have unwittingly been included, the publisher will be pleased to make amends at the earliest possible opportunity. To avoid the issue of disclosure of answer-related information to candidates, all copyright acknowledgements are reproduced online in the Cambridge International Examinations Copyright Acknowledgements Booklet. This is produced for each series of examinations and is freely available to download at www.cie.org.uk after the live examination series. Cambridge International Examinations is part of the Cambridge Assessment Group. Cambridge Assessment is the brand name of University of Cambridge Local Examinations Syndicate (UCLES), which is itself a department of the University of Cambridge. © UCLES 2018 0610/43/O/N/18