PSYC/NEURO 414: BRAIN, LEARNING, AND MEMORY Fall 2018: MWF 1:00-1:50 PM PSYCHOLOGY BUILDING ROOM 23 Important information: Instructor: Amy Perkins (aper1@illinois.edu) Office hours: Office hours: Monday 2-3 pm (Psychology Building Room 512) Course information: Course Description: Welcome to Brain, Learning, and Memory. This course describes current research on the physiological bases of learning and memory. It covers a wide range of topics from molecular (e.g., cellular, morphological, and functional plasticity) to more global (e.g., effects of clinical and experimental brain damage on learning and memory processes). Prerequisites: PSYC 210 (Behavioral Neuroscience), MCB 150 (Molecular and Cellular Basis of Life), or consent of instructor. Required textbook: Neurobiology of Learning and Memory 2nd edition by Jerry W. Rudy. Website: An Illinois Compass 2g website at https://compass2g.illinois.edu/ has been established for this course. It contains lecture slides and grades. You will need your Net ID and password to access the site. DRES accommodations: To ensure that disability-related concerns are properly addressed, students who require assistance to participate in this class are asked to contact the instructor within the first two weeks of the semester and make arrangements for special accommodations through DRES (Division of Disability Resources and Educational Services). Academic Honesty: Cheating will not be tolerated in any form. You are expected to read and abide by the student code of conduct. Anyone caught cheating on an exam, helping another student cheat, or plagiarizing will result in, at minimum, a grade of zero on the test and a maximum grade of ‘C’ for the class. Students must be cognizant of this statement from the College of Liberal Arts and Sciences Student Handbook: “It is the responsibility of the student to refrain from infractions of academic integrity, from conduct that may lead to suspicion of such infractions, and from conduct that aids others in such infractions.” Exams: Four semi-cumulative exams will be given during the regular class on the dates listed below. Each exam will contribute 25% (20% for graduate students) towards your final grade. No makeup exams will be given. However, your lowest exam score will be dropped at the end of the semester. The final exam will contribute 25% (20% for graduate students) towards your final grade. The final exam cannot be dropped. If you cannot take the final exam on the scheduled date, you must notify me one week before the final day of instruction so that special accommodations can be arranged. Graduate Student Requirements: Graduate students will have an additional written assignment described at a later time. This assignment will be work 20% of your final grade. Grading: Your final grade will be based on the following criteria: Page 1 A+ A B+ B C+ C D+ D F 98-100 90-97 88-89 80-87 78-79 70-77 68-69 60-67 0-59 Class Schedule: Date Aug. 27 Aug. 29 Aug. 31 Topic Introduction and Basics of Neuroscience Historical Foundation Historical Foundation Readings None Chapter 1 Chapter 1 Sept. 3 Sept. 5 Sept. 7 LABOR DAY—NO CLASS Memory Modulation Systems Memory Modulation Systems Chapter 13 Chapter 13 Sept. 10 Sept. 12 Sept. 14 Fate of Retrieved Memories Fate of Retrieved Memories Memory Systems & The Hippocampus Chapter 14 Chapter 14/15 Chapter 15 Sept. 17 Sept. 19 Sept. 21 Review EXAM 1 (IN CLASS): CH. 1, 13-15 The Hippocampus Chapter 16 Sept. 24 Sept. 26 Sept. 28 The Hippocampus The MTH System The Cortico-Striatal System Chapter 16 Chapter 17 Chapter 18 Oct. 1 Oct. 3 Oct. 5 Learning About Danger Learning About Danger Review Chapter 19 Chapter 19 Oct. 8 Oct. 10 Oct. 12 EXAM 2 (IN CLASS): CH. 16-19 Mechanisms of Synaptic Plasticity Mechanisms of Synaptic Plasticity Chapter 2 Chapter 2 Oct. 15 Oct. 17 Oct. 19 Modifying Synapses Modifying Synapses Generating and Stabilizing the Trace Chapter 3 Chapter 3 Chapter 4 Oct. 22 Oct. 24 Oct. 26 Generating and Stabilizing the Trace Review EXAM 3 (IN CLASS): CH. 2-4 Chapter 4 Oct. 29 Consolidating Synaptic Changes Chapter 5 Page 2 Oct. 31 Nov. 2 Consolidating Synaptic Changes Consolidating Synaptic Changes Chapter 5/6 Chapter 6 Nov. 5 Nov. 7 Nov. 9 Maintaining the Consolidated Trace Maintaining the Consolidated Trace Toward a Synthesis Chapter 7 Chapter 7 Chapter 8 Nov. 12 Nov. 14 Nov. 16 Toward a Synthesis Review EXAM 4 (IN CLASS): CH. 5-8 Chapter 8 Nov. 19-23 THANKSGIVING BREAK—NO CLASS Nov. 26 Nov. 28 Nov. 30 Making Memories Making Memories Memory Formation Chapter 9 Chapter 9 Chapter 10 Dec. 3 Dec. 5 Dec. 7 Memory Formation Memory Consolidation Memory Consolidation Chapter 10 Chapter 11 Chapter 11 Dec. 10 Dec. 12 Dec. Memory & Aging Review FINAL EXAM (CANNOT BE DROPPED): CH. 9-11 N/A Page 3 TIME/DATE TBD