TUBERCULOSIS

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TUBERCULOSIS

(BRIEF AWARENESS CAMPAIGN)

Basic Facts

Tuberculosis (TB) is a common and deadly infectious disease caused by mycobacteria, mainly

Mycobacterium tuberculosis

• Over 9 million new cases and 2 million deaths per year worldwide

• 1/3rd of the world’s population is infected with M.tuberculosis

Common Causes

• Mycobacterium tuberculosis

• Highly aerobic

• Infects lungs

• Divides every 15-20 hours

• Very resistant to many disinfectants, acid, alkali, drying, etc.

Contagious, spread through air by inhalation of airborne bacteria from infected

• Easier to contract with weak immune system

Common Symptoms

• Cough (2-3 weeks or more)

• Coughing up blood

• Chest pains

• Fever

• Night Sweats

• Feeling weak and tired

• Losing weight without trying

• Decreased or no appetite

Classification of Tuberculosis

Depending on the time of infection and types of response, TB may be classified as;

• Primary Tuberculosis

• It is initiated after first contact with tubercle bacilli

• Secondary Tuberculosis

• Mainly occurs due to Reactivation of Latent infection

• May also due to Exogenous reinfection

• Leads to – Cavitation's of Lungs, Enlargement of Lymph nodes, expectoration of

Bacteria laden sputum

Laboratory Diagnosis

• Test may include

• Chest X-ray

• show air fluid levels as infection progresses

• Physical Examination

• dullness to chest percussion, increased vocal fremitus

• Tuberculin Skin Test

• positive reaction to intradermal injection of tuberculin

• Microbiological detect of smears and cultures

• Blood test

• elevation in white blood cells (WBCs) count with lymphocyte predominance.

Treatment/Prevention

• Positive Skin Test, Negative X-Ray:

• Antibiotic: Isoniazid

• Positive Skin Test, Positive X-Ray:

• Antibiotic: Isoniazid, Rifampin, Ethambutol, Pyrazinamide

• Prevention

• BCG Vaccine

References

• http://www.medicinenet.com/tuberculosis

• http://www.stoptb.org

• http://www.who.int/tb

• http://www.microbiologybytes.com/video/Mtuberculosis.html

• http://www.cdc.gov/TB/topic/basics/default.htm

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