Biology 2nd Semester Diversity, Genetics and Evolution two By Ted Banta Pahoa High and Intermediate School, Big Island, Hawaii lines, turns gene Big Ideas / Major Understandings: What determines structure and function of cells? The DNA molecule Offspring receive genetic information (DNA) from their parents. Chromosomal mutations may lead to genetic variation Unity and Diversity Explain the structural properties of DNA and the role of DNA in heredity passing of traits to offspring and protein synthesis production of protein Assessment Diagram and explain the role of DNA in heredity DNA replication replicating DNA and protein synthesis which includes transcription translation producing mRNA from DNA making protein using tRNA and ribosomes (rRNA) : Explain Mendel's laws of heredity 1 the Law of Segregation and 2 the Law of Independent Assortment The Law of Segregation states that the members of each pair of alleles separate when gametes are formed. A gamete will receive one allele or the other. The Law of Independent assortment states that two or more pairs of alleles segregate independently of one another during gamete formation. And how can the laws can be used to determine the traits of possible offspring Assessment Use Mendel's laws to predict the potential offspring of two parents: Both phenotype and genotype Explain possible causes of chromosomal mutations and their effects on genetic variation Assessment Name human chromosomal disorders Sickle cell anemia Down Syndrome and describe the cause and symptoms of each Cystic Fibrosis Week 21 DNA and Genes – Let’s Make a Protein!! Ch 11.1-2 Pg 280 Week 21 DNA / Nucleus / Gene / Chromosomes / Protein use these words in two sentences chromosomes that are In the ________ nucleus there are _____________ made of ________________ Deoxyribonucleic acid. (aka (DNA)) A section of DNA that codes for a protein is called a gene _______. products substrate enzyme activator Enzymes are proteins that control __________ chemical___________. reactions _________ Nucleotides Nucleic Acids are made of these DNA They consist of 3 molecules bonded together a phosphate group a sugar, and a nitrogenous base RNA DNA has 4 types of nitrogenous bases A T G C • • • • Adenine (A) and Thymine (T) Guanine (G) and Cytosine (C) Watson and Crick _______________ proposed that DNA is composed of two strands twisted together in a helix double ____. DNA replication A process in which DNA in the chromosomes is copied (replicated) Click to see What are the 3 steps of DNA replication 1 DNA unzips - enzyme breaks hydrogen bonds between bases 2. Bases pair 3. Bases bond protein / polymer / amino acid – write as sentence polymers Proteins are ___________composed of strands of amino acids 40 or more ___________ 3 ways RNA differs from DNA RNA is • 1) single stranded (DNA is _________stranded) double • 2) has ribose sugar (DNA has ____________) deoxyribose Thymine • 3) contains uracil (U) (DNA has __________ (T)) nucleic acid nucleic acid Messenger RNA (mRNA) Takes instructions (a message) for making proteins from the DNA in the nucleus to the ribosomes (rRNA) in the cytoplasm rRNA Ribosomal RNA (rRNA) • The assembly line for producing proteins, bonds amino acids together Transfer RNA (tRNA) • Supplies amino acids to the ribosomal RNA (rRNA) Transcription When enzymes make an mRNA copy of a section of DNA (gene) RNA gene Sections of gene that are expressed Exons Sections of a gene that are NOT expressed Introns Not expressed expressed codon / base / amino acid base in • A group of three nitrogenous _____s amino acid is a gene that code for an ______ codon called a ______ protein Translation After transcription, mRNA goes to the ribosome and begins a process which converts mRNA code into a protein Amino acid tRNA rRNA mRNA AND NOW THE QUIZ 1 A process in which DNA in the chromosomes is copied Click to see 2 1 DNA unzips - enzyme breaks hydrogen bonds between bases 2. Bases pair 3. Bases bond 3 polymers Proteins are ___________composed of strands of 40 or more ___________ 4) 2 ways RNA differs from DNA RNA is • 1) ________ stranded • 2) has _______ sugar nucleic acid 5 Takes instructions (a message) for making proteins from the DNA in the nucleus to the ribosomes (rRNA) in the cytoplasm rRNA 6 In the ________ nucleus there are _____________ that are made of ________________ Deoxyribonucleic acid. (aka (DNA)) A section of DNA that codes for a protein is called a _______. 7_________ are proteins that control chemical reactions _________ ___________. 8 The two kinds of nucleic acids, DNA and RNA are made of these They consist of 3 molecules bonded together a phosphate group a sugar, and a nitrogenous base 9 • Supplies amino acids to the ribosomal RNA (rRNA) 10 • The assembly line for producing proteins, bonds amino acids together 11 When enzymes make an mRNA copy of a section of DNA (gene) RNA gene Sections of gene that are expressed 12 Sections of a gene that are NOT expressed Introns Not expressed expressed 13 _______________ proposed that DNA is composed of two strands twisted together in a helix double ____. 14 The two kinds of nucleic acids, DNA and RNA are made of these They consist of 3 molecules bonded together a phosphate group a sugar, and a nitrogenous base codon / base / amino acid base in • A group of three nitrogenous _____s amino acid is a gene that code for an ______ 15 called a ______ protein 16 A process which converts mRNA into a protein Amino acid tRNA rRNA mRNA Mahalo!