BRYAN A. FRY
316 Lombard Street, Philadelphia, PA 19147
bryan_fry@yahoo.com
(512) 417-4507
http://www.bryanfry.net
www.linkedin.com/in/bryan-fry
I am a Ph.D. candidate in Biochemistry & Molecular Biophysics at the University of Pennsylvania, working on synthetic
protein design for electron transfer processes. Before enrolling at UPenn I worked as an engineer for several years,
integrating hardware and software for industrial test and measurement applications. After graduating I hope to find a
challenging job where I can combine my diverse technical skills.
EDUCATION
University of Pennsylvania
Ph.D. Biochemistry & Molecular Biophysics
Philadelphia, PA
Sept 16, 2016
University of Wisconsin
M.S. Mechanical Engineering
• Wisconsin Governor’s Award for Energy Research
Madison, WI
May 1999
1999
Pomona College
B.A. Physics
• Graduated Cum Laude with Departmental Distinction
• Phi Beta Kappa and Sigma Xi inductee
Claremont, CA
June 1997
ACADEMIC RESEARCH EXPERIENCE
University of Pennsylvania – Graduate student with Dr. P. Leslie Dutton
Philadelphia, PA
Studying basic intra- and inter-protein electron transfers using manmade proteins
2012 - present
Expressed and purified synthetic heme-binding proteins designed for
interaction with natural cytochromes.
• Developed laser-induced photolysis methods for measuring interprotein electron
transfer reactions.
• Built Python software for data post-processing and chemical kinetics modeling.
University of Wisconsin – Graduate student with Dr. William Beckman
Developed methodology for modeling building-integrated photovoltaic systems
• Evaluated economic performance given historical weather data and building
electrical loads.
• Numerical modeling in FORTRAN.
Madison, WI
July 1997 – May 1999
Pomona College – Senior thesis with Dr. Thomas Moore
• Programmed thermal model of a passive solar house.
Claremont, CA
Jan – May 1997
University of California, Berkeley – Laboratory of Dr. Eicke Weber
• Electrical characterization of semiconductor samples
Berkeley, CA
June 1996 – Aug 1996
University of Nevada, Las Vegas – Laboratory of Dr. Victor Kwong
• Assembly and of testing of ultrahigh vacuum apparatus for laser ablation
Las Vegas, NV
June 1995 – Aug 1995
ENGINEERING WORK EXPERIENCE
VI Technology (Now Aeroflex) – Senior Software Engineer
• Developed automated test and measurement software
• Optimized laboratory measurement systems
Austin, TX
Jan 2008 – Aug 2009
Graftek Imaging – Systems and Software Engineer
• Developed software for industrial image acquisition and machine vision
Austin, TX
Nov 2004 – Nov 2007
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Designed lighting and optics for machine vision applications
Installed industrial vision systems on site
National Instruments – Staff Product Support Engineer
• Developed and supported software for sound and vibration acquisition
• Provided extensive technical sales support and prototyping
• Award for Excellence in Applications Engineering
Austin, TX
Oct 1999 – Nov 2004
LABORATORY SKILLS
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Time-resolved laser spectroscopy
Developing chemical kinetics models from spectroscopic data
Mutagenesis and E. coli protein expression
FLPC and HPLC protein purifications
Anaerobic chemical techniques
Spectroscopic cofactor binding assays
Extensive test and measurement instrumentation experience
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COMPUTER / SOFTWARE SKILLS
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Proficient in Python / NumPy / SciPy
LabVIEW Certified Architect
o Extensive experience in data acquisition and image acquisition system design and development
Molecular modeling and automation in PyMol
Molecular dynamics simulation in GROMACSåå
Experience in C, R, MatLab, Mathematica, FORTRAN
Experience in UNIX
COMMUNICATION / LEADERSHIP EXPERIENCE
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University of Pennsylvania Penn Biotech Project -- Market research and competition analysis for
Optofluidics, a Philadelphia startup
National Instruments -- Delivered multi-day technical seminars for engineering customers
Pomona College Department of Physics -- Worked as laboratory teaching assistant for four semesters
Programming Tutoring --Taught Python coding to middle school students
SELECTED PUBLICATIONS
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B.A. Fry, L.A. Solomon, P.L. Dutton, C.C Moser. Design and engineering of a man-made diffusive electrontransport protein. BBA Bioenergetics. May 2016.
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G. Goparaju, B.A. Fry, S.E. Chobot, G. Wiedman, C.C. Moser, P.L. Dutton, B.M Discher. First principles
design of a core bioenergetic transmembrane electron transfer protein. BBA Bioenergetics. May 2016.
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B.R. Lichtenstein, C. Bialas, J.F. Cerda, B.A. Fry, P.L. Dutton, C.C. Moser. Designing light-activated chargeseparating proteins with a naphthoquinone amino acid. Angewandte Chemie. 46 (2015) 13626-9.
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T.A. Farid, G. Kodali, L.A. Solomon, B.R. Lichtenstein, M.M. Sheehan, B.A. Fry, C. Bialas, N.M. Ennist, J.A.
Siedlecki, Z. Zhao, M.A. Stetz, K.G. Valentine, J.L.R. Anderson, A.J. Wand, B.M. Discher, C.C. Moser, P.L.
Dutton, Elementary tetrahelical protein design for diverse oxidoreductase functions, Nature Chemical Biology.
9 (2013) 826–833.
OTHER INTERESTS
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Cooking, camping / hiking, cycling, tabletop games