Curriculum Vitae (진효언)
Last updated: 2015-10-15
Hyo-Eon Jin, Ph.D.
Department of Bioengineering, University of California, Berkeley, &
Biological Systems and Engineering, Lawrence Berkeley National Laboratory
https://www.researchgate.net/profile/Hyo_Eon_Jin
http://leelab.berkeley.edu/
EDUCATION
2005/03 – 2009/02
Ph.D. in Pharmaceutical Sciences
College of Pharmacy, Seoul National University, Seoul, Korea
Dissertation: “Reduced Antidiabetic Effect of Metformin and Down-regulation
of Hepatic Oct1 in Rats with Ethynylestradiol-Induced Cholestasis”
(Advisor : Prof. Chang-Koo Shim)
2003/03 – 2005/02
M.S. in Pharmaceutical Sciences
College of Pharmacy, Seoul National University, Seoul, Korea
Dissertation: “Molecular Mechanism of Functional Impairment of the Rat Organic
Anion Transporter 3 by Nitric Oxide Donors” (Advisor : Prof. Chang-Koo Shim)
1999/03 – 2003/02
B.S. in Pharmacy
College of Pharmacy, Seoul National University, Seoul, Korea
PROFESSIONAL EXPERIENCES
2015/09 – Present
Scientist
Bioengineering, Bio-Nanomaterials Lab (Supervisor: Prof. Seung-Wuk Lee)
University of California, Berkeley, Berkeley, CA, USA
2012/01 – Present
Postdoctoral Fellow
Biological Systems and Engineering, Lawrence Berkeley National Laboratory,
Berkeley, CA, USA
2012/01 – 2014/12
Postdoctoral Fellow
Bioengineering, Bio-Nanomaterials Lab (Supervisor: Prof. Seung-Wuk Lee)
University of California, Berkeley, Berkeley, CA, USA
2009/03 – 2011/12
Senior scientist
Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul,
Korea
2011/09 – 2011/12
Lecturer
College of Pharmacy, Duksung Women’s University, Seoul, Korea
2009/03 – 2009/08
Lecturer
College of Health Science, Korea University, Seoul, Korea
1/4
Curriculum Vitae (진효언)
Last updated: 2015-10-15
AWARDS & HONORS
1. Fellowship from National Research Foundation of Korea (NRF) funded by the Ministry of Education,
Science and Technology (2011-2012)
2. Scholarship from Brain Korea 21 (Mar. 2003 ─ Feb. 2009)
3. Lecture & Research Scholarship from Seoul National University, Seoul, Korea (Mar. 2005 - Feb. 2007)
4. Outstanding student scholarship from Women’s Pharmaceutical Association, The Korean Pharmaceutical
Association (Mar. 2002 & SEP. 2002)
PUBLICATIONS
1. H.-E. Jin†, J. Jang†, J. Chung, H. J. Lee, E. Wang, S.-W. Lee, W.-J. Chung (†equal contribution). Biomimetic
self-templated
hierarchical
structures
of
collagen-like
peptide
amphiphiles.
Nano
Letters
doi:10.1021/acs.nanolett.5b03313 (2015)
2. H.-E. Jin, C. Zueger, W.-J. Chung, W. Wong, B. Y. Lee, and S.-W. Lee. Selective and sensitive sensing of
flame retardant chemicals through phage display discovered recognition peptide. Nano Letters DOI:
10.1021/acs.nanolett.5b03678 (2015)
3. J. H. Lee†, H.-E. Jin †, M. Desai, S. Ren, S. Kim and S.-W. Lee. (†equal contribution). Biomimetic sensor
design Nanoscale DOI: 10.1039/C5NR05226B (2015)
4. S. Y. Yoo†, H.-E. Jin †, D. S. Choi, M. Kobayashi, Y. Farouz, S. Wang, S.-W. Lee. (†equal contribution). M13
bacteriophage and adeno-associated virus hybrid for novel tissue engineering material with gene delivery
functions. Adv Healthc Mater. DOI: 10.1002/adhm.201500179 (2015)
5. S.-.E. Jin, H.-E. Jin, S.-S. Hong. Targeting L-type amino acid transporter 1 for anticancer therapy: clinical
impact from diagnostics to therapeutics. Expert Opin Ther Targets 19(10):1-19 (2015)
6. H.-E. Jin, R. Farr, and S.-W. Lee. Collagen mimetic peptide engineered M13 bacteriophage for collagen
targeting and imaging in cancer. Biomaterials 35:9236-9245 (2014)
7. J.-W. Oh, W.-J. Chung, K. Heo, H.-E. Jin, B. Y. Lee, E. Wang, C. Zueger, W. Wong, J. Meyer, C. Kim, S.-Y. Lee,
W.-G. Kim, M. Zemla, M. Auer, A. Hexemer, and S.-W. Lee. Biomimetic virus-based colourimetric sensors.
Nature Communications 5, Article number: 3043 DOI:10.1038/ncomms4043 (2014)
8. D. S. Choi†, H.-E. Jin †, S. Y. Yoo, and S.-W. Lee. (†equal contribution). Cyclic RGD peptide incorporation on
phage major coat proteins for improved internalization by HeLa cells. Bioconjugate Chem. 25(2):216–223
(2014)
9. J. Park, M. Do, H.-E. Jin, S.-W. Lee, H. Lee. M13 bacteriophage displaying DOPA on surfaces: Fabrication of
various nanostructured inorganic materials without time-consuming screening processes. ACS Applied
Materials & Interfaces 6(21):18653−18660 (2014)
10. Y. C. Kim, I.-B. Kim, C.-K. Noh, H. P. Quach, I.-S. Yoon, E. Chow, M. Kim, H.-E. Jin, K. H. Cho, S.-J. Chung, S. K.
2/4
Curriculum Vitae (진효언)
Last updated: 2015-10-15
Pang, and H.-J. Maeng. Effects of 1α,25-dihydroxyvitamin D3, the natural VDR ligand, on the
pharmacokinetics of cefdinir and cefadroxil, OAT substrates, in rat. J Pharm Sci. 103:3793–3805 (2014)
11. H.-E. Jin†, S.-E. Jin†, and H.-J. Maeng. (†equal contribution). Recent bioanalytical methods for
quantification of third-generation cephalosporins using HPLC and LC-MS (/MS) and their applications in
pharmacokinetic studies. Biomed Chromatogr. 28: 1565–1587 (2014)
12. S.-E. Jin, H.-E. Jin, and S.-S. Hong. Targeted delivery system of nanobiomaterials in anticancer therapy:
From cells to clinics. Biomed Res Int. Article ID 814208 (2014)
13. H.-E. Jin, Y. C. Kim, and H.-J. Maeng. Liquid chromatography–tandem mass spectrometry for
quantification of cefaclor in rat plasma and its application to pharmacokinetic studies. Journal of
Pharmaceutical Investigation 44:133–139 (2014)
14. H.-E. Jin†, I.-B. Kim†, Y. C. Kim, K. H. Cho, and H.-J. Maeng. (†equal contribution). Determination of
cefadroxil in rat plasma and urine using LC–MS/MS and its application to pharmacokinetic and urinary
excretion studies. J Chromatogr B Analyt Technol Biomed Life Sci. 947-948:103-10 (2014)
15. H.-E. Jin†, W.-J. Chung†, S.-W. Lee. (†equal contribution). Phage display for the discovery of
hydroxyapatite-associated peptides. Methods Enzymol. 532:305-23 (2013)
16. H.-E. Jin†, I.-B. Kim†, C.-K. Kim, and H.-J. Maeng. (†equal contribution). Determination of cefdinir levels in
rat plasma and urine by high-performance liquid chromatography–tandem mass spectrometry:
application to pharmacokinetics after oral and intravenous administration of cefdinir. Biomed
Chromatogr. 27(11):1423-30 (2013)
17. K.-S. Kim, W.-S. Shim, I. C. Peñac, E.-K. Seo, W.-Y. Kim, H.-E. Jin, D.-D. Kim, S.-J. Chung, J.-H. Cheong, and
C.-K. Shim. Smooth muscle relaxation activity of an aqueous extract of dried immature fruit of Poncirus
trifoliata (PF-W) on an isolated strip of rat ileum. Nat Prod Commun. 8(8):1143-1148 (2013)
18. J.-H. Park, H.-E. Jin, D.-D. Kim, S.-J. Chung, W.-S. Shim, and C.-K. Shim. Chitosan microspheres as an
alveolar macrophage delivery system of ofloxacin via pulmonary inhalation. Int J Pharm. 441(1-2):562569 (2013)
19. H.-E. Jin†, B. Song†, S.-B. Kim, W.-S. Shim, D.-D. Kim, S. Chong, S.-J. Chung, and C.-K. Shim. (†equal
contribution). Transport of gemifloxacin, a 4th generation quinolone antibiotic, in the Caco-2 and
engineered MDCKII cells, and potential involvement of efflux transporters in the intestinal absorption of
the drug. Xenobiotica. 43(4):355-367 (2013)
20. H. Li†, H.-E. Jin†, W.-S. Shim, and C.-K. Shim. (†equal contribution). An improved prediction of the human
in vivo intestinal permeability and BCS class of drugs using the in vitro permeability ratio obtained for rat
intestine using an Ussing chamber system. Drug Dev Ind Pharm. 39(10):1515-1522 (2013)
21. H.-E. Jin, I.-H. Kang, and C.-K. Shim. Fluorescence detection of zabofloxacin, a novel fluoroquinolone
3/4
Curriculum Vitae (진효언)
Last updated: 2015-10-15
antibiotic, in plasma, bile, and urine by HPLC: The first oral and intravenous applications of a
pharmacokinetic study of rats. J Pharm Pharmaceut Sci 14(3):291-305 (2011)
22. H.-E. Jin, K.-R. Lee, I.-H. Kang, S.-J. Chung, C.-K. Shim. Determination of zabofloxacin in rat plasma by
liquid chromatography with mass spectrometry and its application to pharmacokinetic study. J Pharm
Biomed Anal. 54:873-877 (2011)
23. H.-E. Jin, S.-S. Hong, M.-K. Choi, H.-J. Maeng, D.-D. Kim, S.-J. Chung, C.-K. Shim. Reduced antidiabetic
effect of metformin and down-regulation of hepatic Oct1 in rats with ethynylestradiol-induced
cholestasis. Pharm Res. 26(3):549-559 (2009)
24. H. Li†, H.-E. Jin†, W. Kim, Y.-H. Han, D.-D. Kim, S.-J. Chung, C.-K. Shim. (†equal contribution). Involvement
of P-glycoprotein, multidrug resistance protein 2 and breast cancer resistance protein in the transport of
belotecan and topotecan in Caco-2 and MDCKII cells. Pharm Res. 25(11):2601-2612 (2008)
25. H.-W. Chae, I.-W. Kim, H.-E. Jin, D.-D. Kim, S.-J. Chung, C.-K. Shim. Effect of ion-pair formation with bile
salts on the in vitro cellular transport of berberine. Arch Pharm Res. 31(1):103-110 (2008)
26. M.-K. Choi, Q.-R. Jin, H.-E. Jin, C.-K. Shim, D.-Y. Cho, J.-G. Shin, I.-S. Song. Effects of tetraalkylammonium
compounds with different affinities for organic cation transporters on the pharmacokinetics of
metformin. Biopharm Drug Dispos. 28(9):501-510 (2007)
27. H.-J. Maeng, M.-H. Kim, H.-E. Jin, S. M. Shin, T. Tsuruo, S. G. Kim, D.-D. Kim, C.-K. Shim, S.-J. Chung.
Functional induction of P-glycoprotein in the blood-brain barrier of streptozotocin-induced diabetic rats:
evidence for the involvement of nuclear factor-kappaB, a nitrosative stress-sensitive transcription factor,
in the regulation. Drug Metab Dispos. 35(11):1996-2005 (2007)
28. S.-S. Hong, J.-M. Choi, H.-E. Jin, C.-K. Shim. Altered pharmacokinetics and hepatic uptake of TBuMA in
ethynylestradiol-induced cholestasis. Arch Pharm Res. 29(4):323-327 (2006)
4/4