Abstract Central Page 1 sur 222 Your personalized itinerary is below. To remove items from your itinerary, uncheck the associated box. Scheduling conflicts are denoted with a red "!" icon. Withdrawn presentations are denoted with a purple "w" icon. Itinerary Planner User Guide For Tech Support: See the Get Help Now tab in the upper right corner of this web page. For Program Questions: Contact arvoabstracts@arvo.org. Print Itinerary Only Add Itinerary to Calendar Export Itinerary Excel Print Itinerary + Abstracts Add Itinerary + Abstracts to Calendar Export Itinerary + Abstracts Excel SATURDAY, MAY 04, 2013 1. Diabetic Retinopathy: Where Do We Stand and Where Do We Go from Here? SEPARATE REGISTRATION FEE REQUIRED Moderator(s): Arup Das (Univ of New Mexico Sch of Med) and Renu Kowluru (Wayne State Univ/Kresge Eye Inst) 8:30 AM - 4:30 PM; TCC 303 8:30 AM - 8:35 AM View Session Details Introduction Diabetic Retinopathy: Clinical Review Arup Das View Presentation 9:00 AM - 9:15 AM Diabetic Retinopathy: A Long-Term Epidemiologic Perspective Ronald Klein View Presentation 9:15 AM - 9:30 AM Glucose Control - DCCT/EDIC and Other Trials Robert N. Frank View Presentation 9:30 AM - 9:45 AM Lipid Control - ACCORD/FIELD and Other Trials Emily Y. Chew View Presentation 9:45 AM - 10:00 AM Anti-VEGF and Other Pharmacotherapies Lloyd P. Aiello View Presentation Discussion 10:00 AM - 10:15 8:35 AM - 9:00 AM Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary AM 10:15 AM - 10:30 Break Include in Itinerary 10:30 AM - 10:55 Diabetic Retinopathy: Mechanisms – Review George L. King View Presentation Inflammation Timothy S. Kern View Presentation Oxidative Stress: Mediators and Mechanisms Ruth B. Caldwell View Presentation Mitochondrial Damage Sayon Roy View Presentation Angiogenesis John S. Penn View Presentation Discussion Include in Itinerary AM AM 10:55 AM - 11:10 AM 11:10 AM - 11:25 AM 11:25 AM - 11:40 AM 11:40 AM - 11:55 AM 11:55 AM - 12:10 Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary PM 12:10 PM - 1:10 PM Lunch Include in Itinerary Include in Itinerary 2:35 PM - 2:50 PM Metabolic memory and Epigenetic Modifications Renu A. Kowluru View Presentation Clinical & Experimental Studies of the Neurovascular Unit in Diabetic Retinopathy Thomas W. Gardner View Presentation Novel Biomarkers Edward P. Feener View Presentation Imaging in Diabetic Retinopathy-New Frontiers Elias Reichel View Presentation Retinal Drug Delivery: Nanotechnology & Beyond Uday B. Kompella View Presentation Discussion 2:50 PM - 3:05 PM Break Include in Itinerary 3:05 PM - 3:25 PM Cell-based Therapies-Future Maria B. Grant View Presentation Include in Itinerary 1:10 PM - 1:35 PM 1:35 PM - 1:50 PM 1:50 PM - 2:05 PM 2:05 PM - 2:20 PM 2:20 PM - 2:35 PM Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 2 sur 222 Browse the Program Include in Itinerary 4:10 PM - 4:25 PM Laser Therapy – Future Mark S. Blumenkranz View Presentation Teleretinal Surveillance – Myth or Reality for Reducing Preventable Blindness Globally? Sven-Erik Bursell View Presentation DRCR Network – Past Accomplishments and Future Directions Lee M. Jampol View Presentation Discussion 4:25 PM - 4:30 PM Closing Remarks Include in Itinerary 3:25 PM - 3:40 PM View Your Itinerary Society Home Page 3:40 PM - 3:55 PM 3:55 PM - 4:10 PM 2. Entrepreneurship in Ophthalmology: Pathways to Innovation SEPARATE REGISTRATION FEE REQUIRED Moderator(s): Kenneth Mandell (Xcovery Vision) and Samirkumar Patel (Clearside Biomedical) 8:30 AM - 4:30 PM; 606/607 8:30 AM - 8:35 AM View Session Details Welcome Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Introduction Samirkumar R. Patel View Presentation 8:50 AM - 9:15 AM The Life of a Start-Up: A VC Perspective Cedric Bisson View Presentation 9:15 AM - 9:45 AM Development of a Pediatric Vision Screening Device David G. Hunter View Presentation 9:45 AM - 10:15 AM From Big Pharma to a Small Start-up Company Barbara M. Wirostko View Presentation Break 10:15 AM - 10:30 Include in Itinerary 8:35 AM - 8:50 AM Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary AM Include in Itinerary 11:00 AM - 11:30 Regulatory strategy for early stage medical device and drug companies Judy Gordon View Presentation Panel Session 1 11:30 AM - 12:30 Lunch Include in Itinerary 10:30 AM - 11:00 AM Include in Itinerary AM PM 12:30 PM - 1:00 PM Developing a Retinal Prosthesis Device Robert J. Greenberg View Presentation 1:00 PM - 1:30 PM Creating an Ophthalmic Device Incubator Angela Macfarlane View Presentation 1:30 PM - 2:00 PM Biologic Agents for Eye Inflammation Abbie Celniker View Presentation 2:00 PM - 2:15 PM Break Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 2:15 PM - 2:45 PM Panel Session 2 Include in Itinerary 2:45 PM - 3:00 PM Concluding Remarks Kenneth J. Mandell View Presentation Networking Session with Refreshments Include in Itinerary 3:00 PM - 4:30 PM 3. Hands-on Publishing: A Practical Course on Writing and Publishing a Scientific Article SEPARATE REGISTRATION FEE REQUIRED Moderator(s): Pinar Aydin (Eye and Neuro-Ophthal Clinic) and Einar Stefánsson (University of Iceland) 8:30 AM - 4:30 PM; TCC 301/302 8:30 AM - 8:40 AM 8:40 AM - 9:20 AM Include in Itinerary View Session Details Introduction Pinar Aydin View Presentation Panel Discussion - Why Are Articles Rejected? Questions to Ask Yourself Before You Start Writing Einar Stefánsson View Presentation 9:40 AM - 10:00 AM Kinds of Articles and their Special Features Janos Nemeth View Presentation Parts of an Article 10:00 AM - 10:45 Afsun Sahin AM View Presentation Break 10:45 AM - 11:00 AM What Publishers Want 11:00 AM - 11:30 David C. Beebe AM View Presentation How to Choose Where to Submit, Specifications of Ophthalmology Journals 11:30 AM - 12:00 Jeffrey H. Boatright PM View Presentation 12:00 PM - 1:00 PM Lunch 9:20 AM - 9:40 AM Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 2:15 PM - 2:30 PM Tables and Figures Jie Jin Wang View Presentation Ethics in Scientific Publication Pinar Aydin View Presentation Peer-review Process Arun D. Singh View Presentation Break 2:30 PM - 3:30 PM Group Work - Hands On Review of an Article Include in Itinerary 3:30 PM - 4:00 PM Discussion Groups of Article: The Good, the Bad, and the Ugly Include in Itinerary 1:00 PM - 1:20 PM 1:20 PM - 1:40 PM 1:40 PM - 2:15 PM Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 3 sur 222 4:00 PM - 4:25 PM Panel Discussion - Questions and Answers Include in Itinerary 4:25 PM - 4:30 PM Closing Remarks Einar Stefánsson View Presentation Include in Itinerary 4. Ophthalmic Oncology Update: Molecular Signature of Ocular and Orbital Tumors and Targeted Biologic Treatment Opportunities SEPARATE REGISTRATION FEE REQUIRED Moderator(s): Bita Esmaeli (UT MD Anderson Cancer Center), J William Harbour (Bascom Palmer Eye Institute), Brenda Gallie (Princess Margaret Hospital) and Sarah Coupland (Univ of Liverpool/Sydney Jones Library) 8:30 AM - 4:30 PM; 608 View Session Details Include All in Itinerary 8:30 AM - 8:35 AM Opening Remarks Include in Itinerary 8:35 AM - 8:35 AM Targeting BAP-1: From Bench to Bedside and Back Frank Rauscher View Presentation Biopsy and Molecular Testing for Uveal Melanoma Chris Bergstrom View Presentation Recent Animal Models for Uveal Melanoma Didier Decaudin View Presentation Signaling Network Alterations in Uveal Melanoma Cell Lines Scott E. Woodman View Presentation Panel Discussion Include in Itinerary 8:35 AM - 8:50 AM 8:50 AM - 9:05 AM 9:05 AM - 9:20 AM 9:20 AM - 9:45 AM Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 9:45 AM - 10:15 AM Break 10:15 AM - 10:30 AM 10:30 AM - 10:45 AM 10:45 AM - 11:00 AM 11:00 AM - 11:45 AM 11:45 AM - 12:00 Include in Itinerary Novel Anti-VEGF Treatment Concepts for Ocular Surface Malignancies Ludwig M. Heindl View Presentation Animal Model of Ocular GVHD Stella K. Kim View Presentation Conjunctival melanocytic intraepithelial neoplasia (C-MIN) versus Primary acquired melanosis (PAM) Sarah E. Coupland View Presentation Molecular Characteristics of Eyelid Sebaceous Carcinoma Michael T. Tetzlaff View Presentation Panel Discussion Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary PM 12:00 PM - 1:00 PM Lunch Include in Itinerary Include in Itinerary 2:15 PM - 2:45 PM Intra-arterial Chemotherapy for Lacrimal Gland Adenoid Cystic Carcinoma David T. Tse View Presentation Molecular Characteristics and Targetable Molecules in Lacrimal Gland Carcinoma Diana Bell View Presentation Targeted Therapy for Basal Cell Carcinoma: Sonic Hedge Hog Pathway Bita Esmaeli View Presentation Targeting EGFR in Advanced Squamous Cell Carcinoma of Orbit Tarek El-Sawy View Presentation Stem Cell Biology in Orbital Cancer Alon Kahana View Presentation Panel Discussion 2:45 PM - 3:00 PM Break Include in Itinerary 3:00 PM - 3:15 PM Current Controversies in Retinoblastoma J William Harbour View Presentation Intra-arterial Chemotherapy for Retinoblastoma James J. Augsburger View Presentation Current Status of Genetic Testing in Retinoblastoma Brenda L. Gallie View Presentation Insights from Genetically Engineered Mouse Retinoblastoma Models David Cobrinik View Presentation Panel Discussion Include in Itinerary 1:00 PM - 1:15 PM 1:15 PM - 1:30 PM 1:30 PM - 1:45 PM 1:45 PM - 2:00 PM 2:00 PM - 2:15 PM 3:15 PM - 3:30 PM 3:30 PM - 3:45 PM 3:45 PM - 4:00 PM 4:00 PM - 4:30 PM 5. Predicting, Measuring and Treating Changes in Corneal Biomechanics SEPARATE REGISTRATION FEE REQUIRED Moderator(s): Farhad Hafezi (Geneva Univ Hosp/Doheny Eye Inst) and Eberhard Spoerl (University of Dresden) 8:30 AM - 4:30 PM; TCC LL 4/5 Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary View Session Details Include All in Itinerary The Organisation of Corneal Lamellae in the Stroma: Biomechanical and Structural Implications Keith M. Meek View Presentation 8:45 AM - 9:00 AM How Does Collagen Macrostructure Define Corneal Shape. James V. Jester View Presentation 9:00 AM - 9:15 AM Corneal Biomechanics and their Age-related Changes Ahmed Elsheikh View Presentation 9:15 AM - 9:30 AM Hormonal Influences on Biomechanics Zisis Gatzioufas View Presentation 9:30 AM - 9:45 AM The Role of 3-D Collagen Organization in Stromal Elasticity Peter M. Pinsky View Presentation 9:45 AM - 10:00 AM Evaluation of the Response of the Cornea to an Air Puff to Detect Biomechanical Changes Cynthia J. Roberts View Presentation Include in Itinerary 8:30 AM - 8:45 AM Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 4 sur 222 10:00 AM - 10:40 Roundtable Discussion Include in Itinerary 10:40 AM - 10:50 Break Include in Itinerary AM AM Stress-Stain-measurements by Strip Extensiometry Eberhard Spoerl View Presentation Biomechanical Changes Induced by Standard and Rapid CXL 11:10 AM - 11:30 Michael C. Mrochen AM View Presentation Constant Force Elongation Measurements 11:30 AM - 11:50 Olivier Richoz AM View Presentation Airpulse OCT 11:50 AM - 12:10 Susana Marcos PM View Presentation Micro/Nano-indentation Techniques for Biomechanical Characterization of Various 12:10 PM - 12:30 Ocular Tissues PM Lawrence Yoo View Presentation 12:30 PM - 1:10 PM Roundtable Discussion 10:50 AM - 11:10 Include in Itinerary AM Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 1:10 PM - 2:10 PM Lunch Break Include in Itinerary 2:10 PM - 2:30 PM Include in Itinerary 3:00 PM - 3:30 PM CXL (Collagen Cross-linking) - Clinical Results Farhad Hafezi View Presentation Corneal Tomography and Biomechanical Evidence of Crosslinking Renato Ambrosio View Presentation Corneal Topography to Detect Biomechanical Changes Bradley Randleman View Presentation Roundtable Discussion 3:30 PM - 3:45 PM Break Include in Itinerary 3:45 PM - 4:30 PM General Discussion Farhad Hafezi; Eberhard Spoerl View Presentation Include in Itinerary 2:30 PM - 2:50 PM 2:50 PM - 3:00 PM 6. Telehealth Methods for Diabetic Retinopathy and Glaucoma: Clinical, Technical and Business Insights and Strategies for Successful Teleophthalmology Programs SEPARATE REGISTRATION FEE REQUIRED Moderator(s): Ingrid Zimmer-Galler (Johns Hopkins Medical Institutions) and Mark Horton (Phoenix Indian Medical Center) 8:30 AM - 12:00 PM; 615-617 8:30 AM - 8:45 AM 8:45 AM - 9:00 AM 9:00 AM - 9:15 AM View Session Details Background Ingrid E. Zimmer-Galler View Presentation Goals of DR Telemedicine Assessment Programs Paolo S. Silva View Presentation DR Assessment: System Validation Against Gold Standard ETDRS Fundus Photography Paolo S. Silva View Presentation 9:15 AM - 9:45 AM Teleglaucoma: Challenges and Opportunities Louis R. Pasquale View Presentation 9:45 AM - 9:55 AM Telemedicine Program Requirements Mark Horton View Presentation 9:55 AM - 10:05 AM Quality Control Mark Horton View Presentation Break 10:05 AM - 10:20 Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary AM 10:20 AM - 10:35 AM 10:35 AM - 10:50 AM 10:50 AM - 11:10 AM 11:10 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 Financial Factors Ingrid E. Zimmer-Galler; Mark Horton; Paolo S. Silva; Jerry Cavallerano View Presentation Panel Discussion Ingrid E. Zimmer-Galler; Mark Horton; Paolo S. Silva; Jerry Cavallerano View Presentation Current State of Automated Detection/Grading of Diabetic Retinopathy Michael D. Abramoff View Presentation Potential Impact on Conventional Eye Care Programs Jerry Cavallerano View Presentation Examples of Current Telemedicine DR Programs Ingrid E. Zimmer-Galler View Presentation Question and Answer Session Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary PM 7. microRNA and Ocular Disease SEPARATE REGISTRATION FEE REQUIRED Moderator(s): Shusheng Wang (Tulane University) and Martin Friedlander (Scripps Research Institute) 1:00 PM - 4:30 PM; 615-617 1:00 PM - 1:25 PM 1:25 PM - 1:50 PM 1:50 PM - 2:15 PM 2:15 PM - 2:40 PM 2:40 PM - 3:00 PM Introduction to microRNA Biogenesis, Genome and Genetics Sandro Banfi View Presentation microRNA Research Tools Shusheng Wang View Presentation microRNAs in Ocular Angiogenesis Martin Friedlander View Presentation microRNA Discovery in the Eye by Deep Sequencing David A. Simpson View Presentation Break View Session Details Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 5 sur 222 3:00 PM - 3:25 PM 3:25 PM - 3:50 PM 3:50 PM - 4:15 PM 4:15 PM - 4:30 PM microRNAs in Diabetic Retinopathy and Degenerative Retinal Diseases Shunbin Xu View Presentation MicroRNAs as therapeutic targets in glaucoma. Pedro Gonzalez View Presentation microRNA Therapeutics Andreas G. Bader View Presentation Panel Discussion (Questions and Answers) 8. Probability and Statistics Fundamentals for Analyzing Ophthalmic Clinical Studies SEPARATE REGISTRATION FEE REQUIRED Moderator(s): Dale Kennedy (Independent Consultant) and Kathryn Kennedy (Independent Consultant) 1:00 PM - 4:30 PM; 618-620 View Session Details Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary 1:00 PM - 1:10 PM Introduction Include in Itinerary 1:10 PM - 1:25 PM Random Variables and Concept of Variation Dale J. Kennedy View Presentation Fundamentals Of Probability Dale J. Kennedy View Presentation Statistical Inference Process Dale J. Kennedy View Presentation Break Include in Itinerary Review Typical Statistical Analysis Methods Applicable to Ophthalmic Clinical Studies Kathryn S. Kennedy View Presentation Special Topics Such as Multiplicity Corrections and Handling Correlation (E.G., Between Eyes), Statistical Bias, and Controlling Methods to Include Randomization Kathryn S. Kennedy View Presentation Summary and Final Question and Answer Include in Itinerary 1:25 PM - 1:45 PM 1:45 PM - 2:30 PM 2:30 PM - 2:45 PM 2:45 PM - 3:50 PM 3:50 PM - 4:20 PM 4:20 PM - 4:30 PM Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary SUNDAY, MAY 05, 2013 101. Architecture of the Eye: Structural Biology and Vision Moderator(s): T. Michael Redmond (National Eye Institute, NIH ) and Seva Gurevich (Vanderbilt Univ) 8:30 AM - 10:30 AM; 6A 8:30 AM - 8:36 AM View Session Details Introduction Include in Itinerary 8:36 AM - 8:54 AM 1. Deconstructing the Cornea: From Tissue to Molecule Keith M. Meek View Presentation 8:54 AM - 9:12 AM 2. Alpha-Crystallin Heterogeneity Revisited Sevil Weinkauf View Presentation 9:12 AM - 9:30 AM 3. Structure of Rhodopsin Mutants that Constitutively Activate the Receptor Gebhard Schertler View Presentation 9:30 AM - 9:48 AM 4. Cryo-electron Tomography of Cilia-associated Structures in Normal and Diseased Photoreceptors Theodore G. Wensel View Presentation 9:48 AM - 10:06 AM 5. Structure and Function of Synaptic Ribbons Jeffrey Diamond View Presentation 6. The Optic Nerve Head in 3D: Connective Tissue Architecture and Fibre Organisation 10:06 AM - 10:24 in the Young and Old AM Julie Albon View Presentation Discussion & Perspectives 10:24 AM - 10:30 AM 102. From the Cell to Therapy: Transforming Vision and Life Moderator(s): Matthew W. Wilson (University of Tennessee Health Science CenterHamilton Eye Institute), Peter Hitchcock (Univ of Michigan-Kellogg Eye Ctr) and Colm O'Brien (Mater Misericordiae Univ Hospital) 8:30 AM - 10:30 AM; 6E 8:30 AM - 8:35 AM Include All in Itinerary View Session Details Introduction 8:35 AM - 8:50 AM 7. Contact Between the Optic Vesicle and the Surface Ectoderm: A Defining Event in Eye Development David C. Beebe View Presentation 8:50 AM - 9:05 AM 8. Molecular Pathways Disrupted in Developmental Glaucoma Philip J. Gage View Presentation 9:05 AM - 9:20 AM 9. Relevance of Developmental Pathways/Processes in Tumorigenesis Michael Dyer View Presentation 9:20 AM - 9:35 AM 10. Unique Aspects of Drug Delivery to the Eye Henry F. Edelhauser View Presentation 9:35 AM - 9:50 AM 11. Translational Research in Retinoblastoma Using Novel, Targeted Drugs Rachel Brennan View Presentation 9:50 AM - 10:05 AM 12. Neuroprotective Strategies in Photoreceptor Degeneration Tom G. Cotter View Presentation 13. Harnessing developmental biology for regenerative medicine 10:05 AM - 10:20 Thomas A. Reh AM View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 6 sur 222 10:20 AM - 10:30 Conclusion Include in Itinerary AM 103. Imaging of Ocular Vasculature and Flow Moderator(s): Einar Stefánsson (University of Iceland) and Rainer Leitgeb (Medical University of Vienna) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 14 - A0001. A Prospective, Multi-Center Study on the Characteristic Features of Polypoidal Choroidal Vasculopathy on Fluorescein Angiography Colin S. Tan; Nikolle Tan; Tock H. Lim View Presentation 15 - A0002. Detection of Reticular Pseudodrusen (RPD) in Early- and Late-Phase Fluorescein Angiography (FA) Dan Yoon; Jesse T. McCann; Marcela Marsiglia; Ana Rita Santos; Rufino Silva; Maria Luz Cachulo; Jose G. Cunha-Vaz; Roland Smith View Presentation 16 - A0003. Comparison of ultra wide-field fluorescein angiography using the Optos® P200Tx and Heidelberg Spectralis® the non-contact wide-angle lens George J. Parlitsis; Matthew T. Witmer; Sarju Patel; Szilard Kiss View Presentation 17 - A0004. Ultra-widefield Angiographic Assessment of Peripheral Ischemic Burden in Retinal Venous Occlusive Disease with Refractory Macular Edema Jedediah McClintic; Peter K. Kaiser; Rishi Singh; Sunil K. Srivastava; Justis P. Ehlers View Presentation 18 - A0005. Ultra-Widefield Fluorescein Angiography in Children Using Oral Fluorescein Administration Andrew Schneier; David Y. Kim; Deborah VanderVeen; Shizuo Mukai View Presentation 19 - A0006. Microvasculature Imaging by Wide Field Dual-Beam Optical Coherence Angiography Shuichi Makita; Kazuhiro Kurokawa; Masahiro Miura; Yoshiaki Yasuno View Presentation 20 - A0007. High resolution imaging of retinal arteriovenous crossings Aurélie Brolly; Alexandre Leseigneur; Céline Chaumette; Serge Sancho; Edouard Koch; Michel Paques View Presentation 21 - A0008. Retinal Vessel Caliber as a Predictor of Visual Outcome in Eyes with Diabetic Macular Edema (DME) Treated with Ranibizumab Ahmadreza Moradi; Raafay Sophie; Rachel E. Annam; Owhofasa O. Agbedia; Hongting Liu; Mostafa Hanout; Millena G. Bittencourt; Mohamed A. Ibrahim; Diana V. Do; Quan Dong Nguyen View Presentation 22 - A0009. Retinal Vascular Caliber and Hypertension Diagnosis in the Primary Care Setting WanFen Yip; Peter Moey; Ngiap Chuan Tan; Sally Low; Xing Xiu Ho; Lieng Hsi Ling; Tien Y. Wong; Carol Y. Cheung View Presentation 23 - A0010. Retinal Vascular Measurements Using Automated Fundus Image Analysis: The Effect of Hypertension on Vascular Caliber in Adult Population Miriam Englander; Eleftherios I. Paschalis; Tamara J. Lee; Amit Vasanji; Rishi Singh View Presentation 24 - A0011. Evaluation of Relationships between Retinal Microvascular Parametric Changes and Immune Status in Patients with HIV Stephen C. Teoh; Petrina Tan; Carol Y. Cheung; Queenie L. Li; Tun Kuan Yeo; Rupesh V. Agrawal; James Ng; Owen K. Hee; Tock H. Lim; Tien Y. Wong View Presentation 25 - A0012. Three-Dimensional Tomographic Features of Retinal Arteriovenous Crossings on Optical Coherence Tomography Kyoko Kumagai; Akitaka Tsujikawa; Yuki Muraoka; Yumiko Akagi-Kurashige; Ken Ogino; Tomoaki Murakami; Kazuaki Miyamoto; Nagahisa Yoshimura View Presentation 26 - A0013. Comparison of the Changes in Retinal Vessel Caliber in Patients with Age Related Macular Degeneration (AMD) before and after Treatment with Intravitreal Aflibercept Rachel E. Annam; Ahmadreza Moradi; Mostafa Hanout; Mohammad A. Sadiq; Hongting Liu; Owhofasa O. Agbedia; Hyun Soo Jang; Zubir S. Rentiya; Yasir J. Sepah; Quan Dong Nguyen View Presentation 27 - A0014. Variation of Choroidal Thickness and Choroidal Vessel Diameter in Patients with White Dot Syndromes Saleema Kherani; Millena G. Bittencourt; Daniel Ferraz; Hongting Liu; Mehreen Ansari; Mohammad A. sadiq; Raafay Sophie; Rachel E. Annam; Yasir J. Sepah; Quan Dong Nguyen View Presentation 28 - A0015. Improved 3-Dimensional Retinal Vascular Tree Segmentation and Reconstruction from High-Definition Optical Coherence Tomography Pedro Rodrigues; Pedro Guimaraes; Rui Bernardes; Pedro Serranho View Presentation 29 - A0016. Discrimination between perfused and occluded vessels from OCT scans Rui Bernardes; Pedro Guimaraes; Pedro Rodrigues; Joao Figueira; Pedro Serranho View Presentation 30 - A0017. Assessing the influence of cardiovascular signals on ocular pulse Monika E. Danielewska; D Robert Iskander View Presentation 31 - A0018. Carotid Doppler Ultrasound in Ophthalmology: A study of indications and outcomes Tsong Q. Kwong; Moin Mohamed View Presentation 32 - A0019. Bidirectional Doppler OCT for measurement of retinal blood flow Leopold Schmetterer; Rene M. Werkmeister; Gerhard Garhofer View Presentation 33 - A0020. Swept Source OCT imaging of limbal and sclera vessels in vivo using speckle variance detection Kevin Sitko; Al-Hafeez Dhalla; Jonathan J. Liu; Ireneusz Grulkowski; Chen D. Lu; James G. Fujimoto; Yuankai Tao; Jay S. Duker; Chandrasekharan Krishnan View Presentation 34 - A0021. In vivo volumetric imaging of human limbal and scleral vasculature with 1µm swept source phase-variance optical coherence tomography (SSpvOCT) RAJU PODDAR; Robert J. Zawadzki; Dennis E. Cortes; Mark J. Mannis; John S. Werner View Presentation 35 - A0022. Effect of mydriasis on Doppler OCT retinal flood flow measurements Simon R. Bababeygy; Ranjith Kumar Konduru; Bryan K. Hong; Ou Tan; David Huang; Srinivas R. Sadda View Presentation 36 - A0023. OCT angiography as a noinvasive tool for volumetric imaging of retinal microangiopathy Daniel Ruminski; Danuta Bukowska; Bartosz L. Sikorski; Iwona Gorczynska; Dawid Borycki; Maciej Szkulmowski; Maciej Wojtkowski View Presentation Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 7 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 37 - A0024. High resolution Doppler OCT Microangiography and angle-independent blood flow assessment in healthy and diseased retina and choroid Cedric Blatter; Christoph Mitsch; Séverine Coquoz; Branislav Grajciar; Amardeep Singh; Rene M. Werkmeister; Leopold Schmetterer; Ursula Schmidt-Erfurth; Rainer A. Leitgeb View Presentation 38 - A0025. OCT Angiographic Study of Optic Disc Perfusion in Glaucoma Yali Jia; Eric Wei; John C. Morrison; Martin F. Kraus; Joachim M. Hornegger; James G. Fujimoto; David Huang View Presentation 39 - A0026. Assessment of Retinal Blood Flow in Diabetic Retinopathy Using Doppler Fourier-Domain Optical Coherence Tomography Sowmya Srinivas; Muneeswar Nittala; Jennifer C. Lee; Ou Tan; Amani A. Fawzi; David Huang; Srinivas Sadda View Presentation 40 - A0027. Retinal Microvascular Geometric Parameters and Cerebral Microbleeds Yi-Ting Ong; Saima Hilal; Carol Y. Cheung; Monica Saini; Narayanaswamy Venketasubramanian; Ainur R. Anuar; Merwyn Chew; Christopher Chen; Tien Y. Wong; Mohammad K. Ikram View Presentation 41 - A0028. Towards live assessment of human leukocyte dynamics in retinal disease with fluorescein-labeled peripheral blood mononuclear cells Daiju Iwata; Philippa J. Lait; Ashwin Dhanda ; Raul de la Flor; Andrew D. Dick; Yin Shan Eric Ng; Richard W. Lee; David T. Shima View Presentation 42 - A0029. Fluorescence lifetime imaging in retinal vein occlusion Martin S. Zinkernagel; Mathias Abegg; Chantal Dysli; Marcel N. Menke; Jens H. Kowal; Ute E. Wolf-Schnurrbusch; Sebastian Wolf View Presentation 43 - A0030. The Effect of Mild Hypoxia on Retinal Oxygen Saturation Tushar Choudhary; Derek Ball; Andy Harvey View Presentation 44 - A0031. Retinal Oximetry with Scanning Laser Ophthalmoscope Jona V. Kristjansdottir; Sveinn H. Hardarson; Gisli H. Halldorsson; Robert A. Karlsson; Thorunn S. Eliasdottir; Einar Stefánsson View Presentation 45 - A0032. Retinal oximetry using stereo retinal fundus camera with band-pass filter Toshiaki Nakagawa; Atsushi Kakuuchi; Takayoshi Suzuki; Shinji Toyoda View Presentation 46 - A0033. Retinal Oxygen Saturation is Affected in Central Retinal Vein Occlusion Thorunn S. Eliasdottir; David Bragason; Sveinn H. Hardarson; Einar Stefánsson View Presentation 47 - A0034. Ethnic differences or imaging problems: Dual wavelength retinal vessel oximetry in Caucasians and South Asians Rebekka Heitmar View Presentation 48 - A0035. Standardization of Retinal Vessel Oximetry and the Influence of Vessel Diameter Sveinn H. Hardarson; Sindri Traustason; Jona V. Kristjansdottir; Olof B. Olafsdottir; Thorunn S. Eliasdottir; Thor Eysteinsson; Einar Stefánsson View Presentation 49 - A0036. Response of Inner Retinal Oxygen Extraction Fraction to Light Flicker in Rat Pang-yu Teng; Justin Wanek; Norman P. Blair; Mahnaz Shahidi View Presentation 104. Biomechanics; Imaging Moderator(s): J Crawford Downs (University of Alabama at Birmingham) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 50 - A0037. Circumferential Trabecular Meshwork Stiffness in Glaucomatous Eyes Lucinda J. Camras; W Daniel Stamer; David L. Epstein; Pedro Gonzalez; Fan Yuan View Presentation 51 - A0038. Racial variation in deep optic nerve head structures visualized with SD-OCT Kulawan Rojananuangnit; John K. Johnstone; Massimo A. Fazio; Mark Clark; Cynthia Owsley; Brandon Smith; Christopher A. Girkin View Presentation 52 - A0039. The role of glycosaminoglycans in the mechanical behavior of the posterior sclera Barbara Murienne; Harry Quigley; Thao D. Nguyen View Presentation 53 - A0040. Spectral Domain Optical Coherence Tomography (SDOCT) Detected Lamina Cribrosa Compliance Change in Non-human Primate (NHP) Early Experimental Glaucoma (EEG) Lirong Qin; Galen Williams; Stuart K. Gardiner; Brad Fortune; J Crawford C. Downs; Claude F. Burgoyne; Hongli Yang View Presentation 54 - A0041. Regional variation of scleral strains measured on human whole globes using ultrasound speckle tracking Junhua Tang; Richard T. Hart; Cynthia J. Roberts; Paul A. Weber; Xueliang Pan; Jun Liu View Presentation 55 - A0042. Scleral anisotropy and its effects on the optic nerve head biomechanics Thao D. Nguyen; Baptiste Coudrillier; Harry Quigley; Craig Boote View Presentation 56 - A0043. Analysis of retinal ganglion cell in lateral geniculate nucleus using ferret ocular hypertension model Takashi Fujishiro; Makoto Aihara; Chihiro Mayama; Makoto Araie View Presentation 57 - A0044. Lamina cribrosa pore analysis in glaucomatous human optic nerve heads in vivo Rachel V. North; Katharine E. Mortlock; Bethany E. Flynn; James Fergusson; Nick White; Wolfgang Drexler; James E. Morgan; Julie Albon View Presentation 58 - A0045. Laminar Beam Orientation and Connective Tissue Volume Fraction in Three-dimensionally (3D) Reconstructed Optic Nerve Heads (ONH) from Human Donor Eyes Vincent Libertiaux; Rafael Grytz; Juan Reynaud; Christopher A. Girkin; J Crawford C. Downs View Presentation 59 - A0046. Lamina Cribrosa Position and Age Uma J. Damle; Sung Chul Park; Rafael L. Furlanetto; Nora Siegal; Christopher C. Teng; Jeffrey M. Liebmann; Robert Ritch View Presentation 60 - A0047. The Influence of Substrate Stiffness on the Proliferation and Mechanical Properties of Normal and Glaucoma Trabecular Meshwork (NTM and GTM) Cells Baiyun Liu; Jason I. Kilpatrick; Bartlomiej Lukasz; Deborah M. Wallace; Abbot F. Clark; Colm J. O'Brien; Suzanne P. Jarvis View Presentation 61 - A0048. Collagen Microstructure In The Glaucomatous Human Optic Nerve Head: Distribution And Fiber Orientation Julie Albon; Hannah J. Jones; Nick White; Michael P. Fautsch; James E. Morgan; C R. Ethier; Michael J. Girard Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 8 sur 222 View Presentation 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 62 - A0049. Lamina Depth and Pia Insertion are Significant Factors in Optic Nerve Head Biomechanics Jonathan L. Grimm; Richard A. Bilonick; Hiroshi Ishikawa; Gadi Wollstein; Larry Kagemann; Joel S. Schuman; Ian A. Sigal View Presentation 63 - A0050. Valsalva Maneuver, Intraocular Pressure, Cerebrospinal Fluid Pressure, and Optic Disc Topography: Beijing Intracranial and Intraocular Pressure (iCOP) Study Ningli Wang; Zheng Zhang; Jost B. Jonas; Robert Ritch View Presentation 64 - A0051. Variability in Optic Disc Margin and Rim Assessment by Glaucoma Specialists using Color Stereophotographs Helen Koenigsman; Ruojin Ren; Hongli Yang; Stuart K. Gardiner; Juan Reynaud; Robert M. Kinast; Steven L. Mansberger; Brad Fortune; Shaban Demirel; Claude F. Burgoyne View Presentation 65 - A0052. Measuring Micron-Scale Collagen Fiber Orientation in the Lamina Cribrosa and Peripapillary Sclera Ning-Jiun Jan; Jonathan L. Grimm; Kira L. Lathrop; Gadi Wollstein; Larry Kagemann; Joel S. Schuman; Hiroshi Ishikawa; Ian A. Sigal View Presentation 66 - A0053. A Sequential Digital Image Correlation Technique for Improved Strain Mapping in Pressure Inflation Tests of Posterior Sclera Jonathan P. Vande Geest; Jeff D. Pyne; Katia Genovese; Luciana Casaletto View Presentation 67 - A0054. Quantitative Measurement of Sleep Body Position Using a Mobile Device and its Application to the Study of Glaucoma Asymmetry Syril Dorairaj; Jonathan D. Tung; Mona Moshtaghi; John H. Liu; Robert N. Weinreb View Presentation 68 - A0055. Through-thickness Measurement of Porcine Sclera Deformation under Biaxial Loading Using High Resolution Ultrasound Benjamin Cruz Perez; Junhua Tang; Hugh J. Morris; Richard T. Hart; Xueliang Pan; Jun Liu View Presentation 69 - A0056. Correlation between preferred sleeping side and optic disc cupping in healthy and glaucomatous patients Igor Rodrigo Lins da Silva; Natália Y. Valdrighi; Luis G. Biteli; Augusto Paranhos; Tiago S. Prata View Presentation 70 - A0057. Age and glaucoma-related changes in the anisotropic mechanical response of the sclera Baptiste Coudrillier; Jacek K. Pijanka; Craig Boote; Joan L. Jefferys; Harry Quigley; Thao D. Nguyen View Presentation 71 - A0058. Correlation of Posterior Scleral Strains with IOP Increase by Volume Controlled Infusion Hugh J. Morris; Benjamin Cruz Perez; Junhua Tang; Xueliang Pan; Richard T. Hart; Paul A. Weber; Jun Liu View Presentation 72 - A0059. The Biomechanical Response of Optic Nerve Head Astrocytes to Compressive Insult Kenneth W. Olsen; John G. Flanagan View Presentation 73 - A0060. Correlations between Lamina Cribrosa Microarchitecture and Thickness in Normal Non-Human Primate (NHP) Eyes Howard Lockwood; Juan Reynaud; Hongli Yang; Stuart K. Gardiner; J Crawford C. Downs; Claude F. Burgoyne View Presentation 74 - A0061. Optic nerve head and peripapillary morphometrics in myopic glaucoma Sieun Lee; Sherry X. Han; Mei Young; Paul Mackenzie; Mirza Faisal Beg; Marinko V. Sarunic View Presentation 75 - A0062. Local Stiffness of Rat Trabecular Meshwork Fan Yuan; Lucinda J. Camras View Presentation 76 - A0063. Relationship of Optic Disc Cup with Lamina Cribrosa and Prelaminar Tissue in Healthy and Glaucomatous Eyes: In Vivo Quantification with Spectral-Domain Optical Coherence Tomography Roberto M. Vessani; Vitor G. Prado; Paula D. Borba; Paula d. Silva; Igor Matsubara; Augusto Paranhos; Tiago S. Prata View Presentation 77 - A0064. Through-thickness variation of human scleral strains in response to IOP elevation measured by ultrasound speckle tracking Jun Liu; Junhua Tang; Richard T. Hart; Cynthia J. Roberts; Paul A. Weber; Xueliang Pan View Presentation 78 - A0065. Ultrasound Biomicroscopy in Congenital and Aphakic Glaucoma Janet Leath; Carmelina Trimboli-Heidler; Mohamad S. Jaafar View Presentation 79 - A0066. Racial Differences in Human Scleral Material Properties Rafael Grytz; Massimo A. Fazio; Vincent Libertiaux; Luigi Bruno; Stuart K. Gardiner; Christopher A. Girkin; J Crawford C. Downs View Presentation 80 - A0067. An Estimate of Intracranial Force on the Optic Nerve Head in Healthy Individuals John H. Liu; Robert N. Weinreb; Alan R. Hargens View Presentation 81 - A0068. Short-term prospective investigation of filtering bleb by three dimensional anterior-segment optical coherence tomography Sachi Kojima; Toshihiro Inoue; Nakashima Kei-Ichi; Ayako Fukushima; Hidenobu Tanihara View Presentation 82 - A0069. Geometric Morphometric Analysis of the Peripapillary RPE / Bruchs Membrane complex in Glaucomatous and Normal Eyes Robert A. Honkanen; Patrick A. Sibony; Crystal R. Kania; Yuchen Liu; Pranav H. Patel; Kevin Kaplowitz; F. James Rohlf View Presentation 83 - A0070. Reproducibility of Schwalbe’s Line identification using time-domain and spectral-domain OCT Jyotsna Maram; Xiaojing Pan; Zhou Yuan Zhang; Muneeswar Nittala; Peggy W. Romano; Vikas Chopra; Srinivas Sadda View Presentation 84 - A0071. Effect of axial length on false positive rate of sectoral peripapillary retinal nerve fiber layer thickness Wakako Yoshinaga; Takehiro Yamashita; Yuya Kii; Minoru Tanaka; Kumiko Nakao; Taiji Sakamoto View Presentation 85 - A0072. Global and Regional Discordance between Colocalized Heidelberg Retinal Tomograph (HRT) Rim Area and Spectral Domain Optical Coherence Tomography (SDOCT) Minimum Rim Measurements Ruojin Ren; Hongli Yang; Stuart K. Gardiner; Lin He; Juan Reynaud; Brad Fortune; Shaban Demirel; Claude F. Burgoyne Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 9 sur 222 View Presentation 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 86 - A0073. Comparisons of optic disc morphology parameters among different optic disc appearances in primary open angle glaucoma – The Glaucoma Stereo Analysis Study (GSAS) Masaki Tanito; Koji Nitta; Maki Katai; Yasushi Kitaoka; Yu Yokoyama; Kazuko Omodaka; Satoru Tsuda; Toshiaki Nakagawa; Toru Nakazawa View Presentation 87 - A0074. Association between optic disc deformation and lamina cribrosa defects detected on swept-source optical coherence tomography in highly myopic eyes with glaucoma Yugo Kimura; Masanori Hangai; Kohei Takayama; Hiroshi Yamada; Kenji Suda; Tomoko Hasegawa; Noriyuki Unoki; Tadamichi Akagi; Hanako O. Ikeda; Nagahisa Yoshimura View Presentation 88 - A0075. Reproducibility of SD-OCT-Based Ganglion-Cell-Complex-Layer Thickness in Early Glaucoma using Commercial and Custom Segmentation Algorithms Mona K. Garvin; Kyungmoo Lee; Trudy L. Burns; Michael D. Abramoff; Andreas Wahle; Milan Sonka; Young H. Kwon View Presentation 89 - A0076. Observation of human lamina cribrosa in vivo using a novel high sensitive, high resolution optical coherence tomography Takuhei Shoji; Shin Yoneya; Masayuki Suzuki; Motoyoshi Baba; Hiroto Kuroda View Presentation 90 - A0077. The Effects of Correcting for Ocular Magnification on Retinal Nerve Fiber Layer and Retinal Ganglion Cell Layer Thicknesses in Macular fdOCT Scans David W. Rhee; Alyssa C. Ehrlich; Ali S. Raza; Jonathan P. Greenberg; Tobias Duncker; Vivienne C. Greenstein; Donald C. Hood View Presentation 91 - A0078. Comparison of Optic Nerve Head Parameters in Myopic and Nonmyopic Glaucoma Eyes Deana Choi; Martha Kim; Karine D. Bojikian; Mark A. Slabaugh; Philip P. Chen View Presentation 92 - A0079. The Location of Peripapillary Glaucomatous Defects Seen on FrequencyDomain OCT Scans Diane L. Wang; Ali S. Raza; C. Gustavo De Moraes; Jeffrey M. Liebmann; Robert Ritch; Donald C. Hood View Presentation 93 - A0080. Diagnostic ability of Spectral Domain Optical Coherence Tomography to Detect Diffuse Retinal Nerve Fiber Layer Atrophy: Diffuse Atrophy Imaging Study Seok Hwan Kim; Ko Eun Kim; Jin Wook Jeoung; Ki Ho Park; Dong Myung Kim View Presentation 94 - A0081. Peripapillary tilting and central visual field loss in Normal Tension Glaucoma using High-Penetration Optic Coherence Tomography Shinichi Usui; Yasushi Ikuno; Yukari Jo; Tomoko Asai; Tsutomu Kikawa; Masahiro Akiba; Kohji Nishida View Presentation 95 - A0082. Imaging the Iris with Swept Source Optical Coherence Tomography – Impact of Iris Volume Measurement on Primary Angle Closure Heather K. Mak; Guihua Xu; Christopher K. Leung View Presentation 96 - A0083. Diagnostic Efficacy of RNFL Thickness Sectors for Glaucoma Detection Gary Lee; Donald L. Budenz; Robert Chang; Alan S. Crandall; Christopher A. Girkin; Christopher K. Leung; Arvind Neelakantan; James H. Peace; John S. Werner; Gadi Wollstein View Presentation 97 - A0084. Comparative evaluation of anterior segment parameters in subgroups of primary angle closure using anterior segment optical coherence tomography Celeste Guzman; Tianxia Gong; Monisha E. Nongpiur; Shamira Perera; Hwee Kuan Lee; Cheng Li; Baskaran Mani; Mingguang He; Alicia How; Tin Aung View Presentation 98 - A0085. Racial Differences in Optic Nerve Head (ONH) and Laminar Surface Compliance in Normal Human Subjects Brandon Smith; John K. Johnstone; Kulawan Rojananuangnit; J Crawford C. Downs; Massimo A. Fazio; Cynthia Owsley; Mark Clark; Christopher A. Girkin View Presentation 105. Inflammation and Drugs Moderator(s): Claudio Bucolo (University of Catania) and Tonia Rex (Vanderbilt University) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM View Session Details 99 - C0104. Zylet (loteprednol etabonate 0.5%/tobramycin 0.3%) Compared with Tobradex (dexamethasone 0.1%/tobramycin 0.3%) for the Treatment of Lid Inflammation in Two Populations Timothy L. Comstock; Heleen H. DeCory; Kirk Bateman View Presentation 8:30 AM - 10:15 AM 100 - C0105. Inflammatory processes in branch retinal vein occlusion in mice Elisa Dominguez; Sophie Cavallero; William Raoul; Sophie Lavalette; Michel Paques; Florian Sennlaub View Presentation 8:30 AM - 10:15 AM 101 - C0106. IL-12p35 Inhibits Th1 proliferation and promotes the expansion of Th17 and Treg Ivy M. Dambuza; Chengrong Yu; Rashid M. Mahdi; Renxi Wang; Sung-Hye Kim; Charles E. Egwuagu View Presentation 8:30 AM - 10:15 AM 102 - C0107. Anti-inflammatory Properties of Resveratrol Improve the Treatment of Diabetic Retinopathy Hamid Ahmadieh; Farhad Ghadiri Soufi; Daryoush Mohammad-Nejad; Ali HafeziMoghadam View Presentation 8:30 AM - 10:15 AM 103 - C0108. Secretion of IL-1α, IL-1β, IL-6 and IL-8 in human keratocyte cell cultures following photodynamic inactivation (PDI) Berthold Seitz; Tanja Stachon; Jiong Wang; Nora Szentmáry View Presentation 8:30 AM - 10:15 AM 104 - C0109. Comparison of retinal and cerebral inflammatory responses after middle cerebral artery occlusion Rachael S. Allen; Iqbal Sayeed; Heather A. Cale; Katherine C. Morrison; Paul H. Choi; Jeffrey H. Boatright; Machelle T. Pardue; Donald G. Stein View Presentation 8:30 AM - 10:15 AM 105 - C0110. Efficacy of 0.5% Indomethacin Eyedrops in Uveitic Macular Edema: a Randomized, Double-blind, Placebo-controlled Clinical Trial Monica Zurria; Pia Allegri; Simona Peri; Rosanna Carniglia De Carli; Maria Grazia Crivelli; Silvia Compiano; Silvia Autuori; Antonio Mastromarino; Ugo Murialdo View Presentation 8:30 AM - 10:15 AM 106 - C0111. Changes in cytokine profile with liposomes sprayed on the ocular surface and nasal mucosa Davide Scollo; Teresio Avitabile; Giulia Malaguarnera; Roberta Amato; Giuseppe Napolitano; Giuseppina Marrazzo; Michele Reibaldi; Antonio Longo; Caterina Gagliano View Presentation 107 - C0112. Systemic factors impacting intraocular levels of vascular endothelial growth 8:30 AM - 10:15 AM factor and interleukin-6 in diabetic retinopathy Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 10 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Sohee Jeon; Won Ki Lee View Presentation 108 - C0113. Effects of topical indomethacin, bromfenac, and nepafenac on LPSinduced inflammation Claudio Bucolo; Giuseppina Marrazzo; Chiara Bianca Maria Platania; Monica Zurria; Filippo Drago View Presentation 109 - C0114. Anti-Inflammatory Effects of NOV C-ter in the Endotoxin-Induced Uveitis model: Down-regulation of Pro-inflammatory Cytokines Chadi Mehanna; Norbert J. Minet; Marie-Chritine Naud; Celine Olmiere; Jean-Louis Bourges; Francine F. Behar-Cohen View Presentation 110 - C0115. Validation of the Anterior Chamber Paracentesis Model for the Screening of Novel Ophthalmic Anti-Inflammatory Drug Laura Belen; Kortni Violette; Jennifer Brackett; Andy Whitlock View Presentation 111 - C0116. Comparison of effects between glucocorticoids and mapracorat after repeat topical ocular administration in rabbits for 28 days Kathleen Krenzer; Sherwin Jiang; Ezra R. Lowe; Mary Richardson View Presentation 112 - C0117. Efficacy of Tocilizumab, an IL-6 receptor inhibitor in ocular inflammatory disorders: a pilot study Vimal Sarup; Anum Butt; Kanza Aziz; C. Stephen Foster View Presentation 113 - C0118. Evaluation of XG-102 effects in the treatment of endotoxin-induced uveitis in rats Ikram El-Zaoui; Elodie Touchard; Marianne Berdugo Polak ; Claire Abadie; Catherine Deloche; Jean-Marc Combette; Francine F. Behar-Cohen View Presentation 114 - C0119. Systemic symvastatin rescues death of retinal ganglion cells from optic nerve injury possibly through suppression of glial NF-κB activation Seita Morishita; Hidehiro Oku; Masahiro Tonari; Teruyo Kida; Taeko Horie; Tsunehiko Ikeda View Presentation 115 - C0120. Infliximab Attenuates Tumor Necrosis Factor-α-Induced Alterations in NonPigmented Ciliary Epithelium Hiroshi Yamada; Masahiko Yoneda; Shingo Inaguma; Masayoshi Iwaki; Masahiro Zako View Presentation 116 - C0121. Ocular Pharmacokinetics of 0.2% and 0.4% Ketorolac Tromethamine Formulated in DuraSite or DuraSite 2 Delivery Systems Compared to Acular LS in Rabbits Afshin Shafiee; Lyle M. Bowman; Eddie Hou; Kamran Hosseini View Presentation 117 - C0122. ITF2357 regulates IL-10 via JAK/STAT signaling pathway to attenuate inflammation and fibrosis Shyam S. Chaurasia; Yu-Chi Liu; Alison Tan; Rayne Lim; Jodhbir S. Mehta View Presentation 118 - C0123. Lack of Correlation between PGE2 levels and Blood Aqueous Barrier Inhibition in a rabbit model of ocular inflammation L David Waterbury View Presentation 119 - C0124. Suprachoroidal Microinjection of Triamcinolone Acetonide is Well Tolerated in the Albino Rabbit Rozemarijn S. Verhoeven; Samirkumar R. Patel; Karen Viaud-Quentric; Florian Cacciamani; Thierry Amar; Benjamin Yerxa View Presentation 120 - C0125. Assessment of Efficacy and Safety of a Novel Protocol for Pulsed Intravenous Cyclophosphamide for Recalcitrant or Severe Ocular Inflammatory Disease Ana M. Suelves; Cheryl A. Arcinue; Jesús María González-Martín; C. Stephen Foster View Presentation 121 - C0126. Acute serous retinal detachment after uncomplicated cataract surgery Maurizio G. Uva; Antonio Longo; Michele Reibaldi; Mario D. Toro; Vincenza Bonfiglio; Faro Giuseppe; Andrea Russo; Caterina Gagliano; Teresio Avitabile View Presentation 122 - C0127. Clinical Outcomes Using Loteprednol 0.5% for treatment of ocular inflammation associated with cataract surgery Melissa M. Toyos View Presentation 14 8:30 AM - 10:15 AM 123 - C0128. 24-Hour Evaluation of the Ocular Pharmacokinetics of C-Labeled LowConcentration, Modified Bromfenac Ophthalmic Solution Following Topical Instillation into the Eyes of New Zealand White Rabbits George Baklayan View Presentation 8:30 AM - 10:15 AM 124 - C0129. Comparison of Methotrexate and Mycophenolate in the Treatment of Chronic Uveitis Tiffany Truong; Zvi A. Kresch; Sanjay R. Kedhar; Vicente Diaz; John V. Mauro; C. Michael Samson View Presentation 8:30 AM - 10:15 AM 125 - C0130. Randomized, Placebo-Controlled, Integrated Phase III Clinical Trials of a Once Daily, Low-Concentration, Modified Bromfenac Ophthalmic Solution Following Cataract Surgery: Focus on Zero to Trace Anterior Chamber Inflammation James A. Gow; James D. Boyce; Harvey J. Reiser; Robert Berry; Jung T. Dao; Simon P. Chandler View Presentation 106. Posterior Segment Infection/AIDS-Related Ocular Disease Moderator(s): Richard Dix (Georgia State University) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 126 - C0131. Infiltrating granulocytes and resident Muller cells are major sources for suppressor of cytokine signaling (SOCS)1 and SOCS3 production during murine cytomegalovirus (MCMV) retinitis in mice with retrovirus-induced immunosuppression (MAIDS) Richard D. Dix; Christine I. Alston; Emily L. Blalock; Jessica Fleming; Hsin Chien View Presentation 127 - C0132. Murine Cytomegalovirus (MCMV) Lacking m38.5 or m41.1 Increases Apoptosis of Viral Infected Retinal Cells Jason Covar; Juan Mo; Brendan Marshall; Sally S. Atherton; Ming Zhang View Presentation 128 - C0133. Suppressor of cytokine signaling (SOCS)1 and SOCS3 expression is upregulated following intraocular, but not systemic, murine cytomegalovirus (MCMV) infection of mice with retrovirus-induced immunosuppression (MAIDS) Christine I. Alston; Hsin Chien; Moon K. Han; Richard D. Dix View Presentation 129 - C0134. The M33 gene of murine cytomegalovirus (MCMV) is involved in the stimulation of VEGF-A production by mouse macrophages Moon K. Han; Hsin Chien; Hamed Laroui; Didier Merlin; Scott W. Cousins; Richard D. Dix View Presentation 130 - C0135. Autophagy Is Anti-apoptotic during Murine Cytomegalovirus (MCMV) Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 11 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Infection of the Retina or RPE Cells Juan Mo; Ming Zhang; Brendan Marshall; Jason Covar; Sally S. Atherton View Presentation 131 - C0136. Cell death pathway inhibitors do not significantly reduce the frequency or severity of murine cytomegalovirus (MCMV) retinitis in mice with retrovirus-induced Immunosuppression (MAIDS) Hsin Chien; Emily L. Blalock; Christine I. Alston; Richard D. Dix View Presentation 132 - C0137. Inhibition of Autophagy by HSV-1 Beclin-Binding Domain (BBD) Induces Apoptosis of Viral Infected Retinas Ming Zhang; Jason Covar; Juan Mo; Sally S. Atherton; Brendan Marshall View Presentation 133 - C0138. Role of Immunomodulatory Therapy for Herpes Simplex Virus Associated Ocular Inflammation Asima Bajwa; Sandra Hu-Torres; C. Stephen Foster View Presentation 134 - C0139. The effects of systemic LPS and CpG-ODN on retinal microglia in the Ins2Akita mouse Jelena M. Kezic; Paul G. McMenamin View Presentation 135 - C0140. Pro-inflammatory Responses Induced by CD40 Ligation in Retinal Endothelial Cells and Muller Cells are TRAF Dependent Carlos Subauste; Jose-Andres C. Portillo; Isaac Schwatrz; Maria Cecilia Subauste View Presentation 136 - C0141. Role of Toll like Receptor 5 (TLR5) in Experimental Bacillus cereus Endophthalmitis Salai Madhumathi Arasi Parkunan; Nanette R. Wheatley; Michelle C. Callegan View Presentation 137 - C0142. The pathogenicity island-encoded AraC-type transcriptional regulator, PerA, contributes to the course and severity of Enterococcus faecalis endophthalmitis Phillip Coburn; Frederick C. Miller; Michelle C. Callegan View Presentation 138 - C0143. Visual outcome of ocular toxoplasmosis in an University Center in Argentina Bernardo A. Schlaen; Mariana Ingolotti; Cristina E. Wong Pang; Jorge Mancini; Maria Noel Gabin; Cristobal A. Couto; Mario J. Saravia View Presentation 139 - C0144. Frequency of relapse in ocular toxoplasmosis Mira Ruppenstein; Michael Reich; Matthias D. Becker; Friederike Mackensen View Presentation 107. Retina/RPE/AMD/Tumor Immunobiology Moderator(s): Rafael Ufret-Vincenty (UT Southwestern Medical Center) and Andrew Taylor (Boston Univ School of Medicine) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 140 - C0145. Gene Expression Profile of Ccl2/Cx3cr1 Double Deficient, Ccl2 Deficient or Cx3cr1 Deficient Mice with or without rd8 Background De Fen Shen; Yujuan F. Wang; Jingsheng Tuo; Xi K. Chu; Chi-Chao Chan View Presentation 141 - C0146. Inflammatory Cytokines in Age Related Macular Degeneration (AMD): Relationships to Disease Activity Khaled Nassar; Elshaymaa Elfar; Julia Lüke; Matthias Lüke; Salvatore Grisanti View Presentation 142 - C0147. Inflammatory cytokines in the vitreous of postmortem eyes: Relationship to age and drusen load Jay Ching-Chieh Wang; Sijia Cao; Aikun Wang; Jing Z. Cui; Joanne A. Matsubara View Presentation 143 - C0148. IL17A inhibits expression of POMC gene in RPE cells Shujie Zhang; Jihong Wu View Presentation 144 - C0149. Retinal pigment epithelial (RPE) cells convert bone marrow derived macrophages into myeloid-derived suppressor cells with a novel phenotype Heping Xu; Chang Luo; Mei Chen View Presentation 145 - C0150. Retinal pigment epithelial cells (RPE) induced from induced pluripotent stem (iPS) cells inhibit activation of T cells in vitro Sunao Sugita; Masayo Takahashi View Presentation 146 - C0151. Effects of bisphosphonates on cytotoxicity and cytokine expression in hRPE cells in vitro Chris Or; Jing Z. Cui; Joanne A. Matsubara; Farzin Forooghian View Presentation 147 - C0152. TNF-α and Aβ promote activation of metalloproteinases in retinal pigment epithelial cells and is mediated by the NF-κB pathway: implications for AMD pathogenesis Brett Poulis; Aikun Wang; Jing Z. Cui; Luba Kojic; Joanne A. Matsubara View Presentation 148 - C0153. Targeting the Inflammasome with the Caspase Activation Recruitment Domain (CARD) in an In Vitro Model of RPE Inflammation Cristhian J. Ildefonso; Henrique Jaime; Alfred S. Lewin View Presentation 149 - C0154. NLRP3 inflammasome activation in human retinal pigment epithelium under inflammation and oxidative stress Yujuan Wang; Mones S. Abu-Asab; DeFen Shen; Xi K. Chu; Alexander J. Ogilvy; Jingsheng Tuo; Chi-Chao Chan View Presentation 150 - C0155. 7-Ketocholesterol Induces Interleukin(IL)-1 beta and IL-18 Production in RPE Cells via Activation of the Inflammasome Guangpu Shi; Osato J. Ogbeifun; Lindsey F. Nugent; Ignacio R. Rodriguez; Igal Gery View Presentation 151 - C0156. Modulation of Laser-Induced Choroidal Neovascularization by Differentiated Macrophages from Patients with Age Related Macular Degeneration Shira Levi; Tareq Z. Jaouni; Michelle Grunin; Tal Burstyn-Cohen; Itay Chowers View Presentation 152 - C0157. Gene Expression Signature in the Monocyte Population of Patients with Age-Related Macular Degeneration Michelle Grunin; Shira Levi; Tal Burstyn-Cohen; Itay Chowers View Presentation 153 - C0158. Recombinant VEGF165b inhibits TNF-α-induced ICAM-1 expression and monocyte adhesion in primary human retinal pigment epithelial cells Peeradech Thichanpiang; David O. Bates; Kanokpan Wongprasert View Presentation 154 - C0159. Recruited macrophages phagocytose damaged RPE mediating onset of angiogenesis Jian Liu; David A. Copland; Shintaro Horie; Wei-Kang Wu; Mei Chen; Yunhe Xu; Heping Xu; Lindsay B. Nicholson; Andrew D. Dick View Presentation 155 - C0160. CD200 Receptor signaling subverts pro-angiogenic macrophage Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 12 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM phenotype generation and experimental chorioretinal neovascularisation Shintaro Horie; David A. Copland; Jian Liu; Wei-Kang Wu; Lindsay B. Nicholson; Manabu Mochizuki; Andrew D. Dick View Presentation 156 - C0161. The role of Fcγ receptors in immune-complex-mediated inflammation in the retina: implications for early age related macular degeneration Salome Murinello; Andrew J. Lotery; V. Hugh Perry; Robert F. Mullins; Jessica L. Teeling View Presentation 157 - C0162. The Correlation of Plasma Cytokines with Complement Factor H polymorphism Y402H, Choroidal Thickness and Drusen Load in Dry Age-Related Macular Degeneration Sijia Cao; Ashley Ko; Aikun Wang; Marita Partanen; Andrew Merkur; David A. Albiani; Andrew W. Kirker; Jing Z. Cui; Farzin Forooghian; Joanne A. Matsubara View Presentation 158 - C0163. Systemic administration of aurin tricarboxylic acid (ATA) reduces C5b-9 immunoreactivity and TUNEL+ cells in the rodent eye: A potential treatment for suppressing complement activation and apoptosis associated with AMD Jenifer Van; Jing Z. Cui; Eleanor To; Patrick McGeer; Joanne A. Matsubara View Presentation 159 - C0164. Curcumin, Luteolin and DHA Supplementation Abates Microglia Activation and Retinal Degeneration in the CLN6nclf Neuronal Ceroid Lipofuscinosis Mouse Model Myriam Mirza; Cornelia Volz; Herbert Jägle; Thomas Langmann View Presentation 160 - C0165. XIAP Protects RPE Cells from Oligomeric Aβ1-40 Induced Cell Death Jiangyuan Gao; Aikun Wang; Jing Z. Cui; Catherine Tsilfidis; Joanne A. Matsubara View Presentation 161 - C0166. Increased Fundus Autofluorescence and Retinal Cell Infiltration in MiddleAged Mice Fed with High Fat, Cholesterol-Rich Diet Zhen-Yang Zhao; Yiqin Zuo; Pei Xu; Bo Yu; Massoud Motamedi; Adam Boretsky; Yan Chen; Jiyang Cai View Presentation 162 - C0167. Change in the distribution and phenotype of subretinal macrophages with aging in C57BL/6 mice Bogale Aredo; xiao chen; Kaiyan Zhang ; Rafael Ufret-Vincenty View Presentation 163 - C0168. Effect of Posterior Segment Components on BV-2 Microglial cell M1/M2 polarization Bongsu Kim; Rania Kusibati; Elaine M. Binkley; Jonathan P. Godbout; Andrew J. Fischer; Colleen M. Cebulla View Presentation 164 - C0169. IgG Autoimmunity Analysis In Aqueous Humor Of Patients With Pseudoexfoliation Syndrome, Pseudoexfoliation Glaucoma and Cataract Controls Joanna Wasielica-Poslednik; Katrin Lorenz; Marcus Schlich; Norbert Pfeiffer; Franz H. Grus View Presentation 165 - C0170. Phenotypical characterization of T cells in allergic conjunctivitis patients showed a diminished frequency of Tregs with increased frequency of CCR4+ and CCR9+ cells Jose Luis Palomares-Ordonez; Jorge Galicia-Carreón; Enrique Hong; Mayra S. PérezTapia; Maria C. Jimenez-Martinez View Presentation 166 - C0171. An enhanced inflammatory response in the aged choroid is associated with the upregulation of CCL2 and neutrophil markers following the induction of choroidal neovascularisation Scott J. Robbie; Ulrich F. Luhmann; Anastasios Georgiadis; Susie E. Barker; Yanai Duran; Alexander J. Smith; Robin R. Ali; James W. Bainbridge View Presentation 167 - C0172. Differential effects of a MyD88 knockout on ocular inflammation induced by the TLR2/3/4 ligands (PAM3CSK4, PolyI:C, and LPS) Maura Crowley; Omar Delgado; Steve Louie; Michael Stefanidakis; Bruce D. Jaffee; Sha-Mei Liao View Presentation 168 - C0173. Critical role of TLR2 and MyD88 signaling in controlling bacterial burden in mouse model of S. aureus endophthalmitis Ashok Kumar; Pawan Kumar Singh; Deepa Talreja View Presentation 169 - C0174. Significance of measuring immune mediators for differentiating malignant from benign pigmented intraocular tumors Yoshihiko Usui; Shunichiro Ueda; Yoko Okunuki; Kinya Tsubota; Kazuki Tajima; Takeshi Kezuka; Yoshihiro Wakabayashi; Hiroshi Goto View Presentation 170 - C0175. Transcriptional Regulatory Network Analysis of Uveal Melanoma Ronald Tongbai; Jennifer Vargas; Gintien Huang; Bradley R. Straatsma View Presentation 171 - C0176. EFFICACY OF SYSTEMIC RITUXIMAB INJECTION FOR TREATING PRIMARY OCULAR ADNEXAL MALT LYMPHOMA Noriyasu Hashida; Kenji Matsushita; Kohji Nishida View Presentation 172 - C0177. Inflammatory stress upregulates chemokine gene expression in uveal melanoma cell lines resulting in increased monocyte chemotaxis Tina Jehs; Helene B. Juel; Carsten Faber; Inge H. Bronkhorst; Martine M. Jager; Mogens H. Nissen View Presentation 173 - C0178. The Expression and meanning of Skp2, p27, PTEN proteins in nonHodgkin B-cell lymphoma of ocular adnexa Guiqiu Zhao; Jing Lin; Qian Wang; Qiang Xu View Presentation 108. Eye Movements: Behavior in Normal and Diseased States Moderator(s): Vallabh Das (University of Houston) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 174 - C0198. Impaired Vestibular Ocular Reflex (VOR) in presymptomatic Spinocerebellar Ataxia Type 3 (SCA-3) Ari Z. Zivotofsky; Avi Caspi; Carlos R. Gordon View Presentation 175 - C0199. Cross-sectional Analysis of Pro- and Antisaccade Development in Retinopathy-Confirmed Cerebral Malaria Paul C. Knox; Ian J. MacCormick; Ruairidh I. Watson; Macpherson Mallewa; Simon P. Harding View Presentation 176 - C0200. Baseline OKN and OKN suppression during divided attention tasks are differently affected by multiple sclerosis Larry A. Abel; Elizabeth A. Bowman; Isla M. Williams View Presentation 177 - C0201. Temporal Pattern of Short-Term Saccadic Adaptation in Amblyopia Rana Arham Raashid; Herbert C. Goltz; Alan Blakeman; Manokaraananthan Chandrakumar; Agnes M. Wong View Presentation 178 - C0202. Characteristics of Ocular Drifts During Fixation in Amblyopia Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 13 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Esther G. Gonzalez; Agnes M. Wong; Manokaraananthan Chandrakumar; Luke Gane; Martin J. Steinbach View Presentation 179 - C0203. Visual acuity in infantile nystagmus in the absence of image motion Matt J. Dunn; Tom H. Margrain; Fergal A. Ennis; Christopher M. Harris; J. M. Woodhouse; Jonathan T. Erichsen View Presentation 180 - C0204. Accuracy of corrective saccade in the dark depends on the latency of the primary saccade Jing Tian; Howard S. Ying; David S. Zee View Presentation 181 - C0205. Quick phase of the torsion vestibulo-ocular reflex increases the gain of the slow phase both before and after the quick phase Robert B. Geary; Howard S. Ying; Kristina Irsch View Presentation 182 - C0206. Eye-Movement Analysis in Relationship to Birth Order in Children Christine Allison; Darrell G. Schlange View Presentation 183 - C0207. Fixation precision in reading estimated with an added noise paradigm Shelby Gross; Scott Stevenson; Emily Horn; Alyssa Ford View Presentation 184 - C0208. Fatigue-induced impairments in saccade velocity are reversed by caffeine Charlotte J. Connell; Benjamin Thompson; Shelley Duncan; Michael Claffey; Gustav Kuhn; Nicholas Gant View Presentation 185 - C0209. Image Size and the Range of Clear and Single Binocular Vision in 3D Displays Kathryn Kulowski; Glen L. McCormack View Presentation 186 - C0210. Heterophoria and motor fusion in infants and pre-school children Vidhyapriya Sreenivasan; Erin Babinsky; T R. Candy View Presentation 187 - C0211. The Convergence Depth Cue and Hand Guidance Caryn Nearnberg; Glen L. McCormack View Presentation 188 - C0212. Effects of changes in pupil centration and pupil size on the output of video eye trackers Ulrich F. Wildenmann; Frank Schaeffel View Presentation 189 - C0213. Comparing Visual Thresholds Measured with Manual Perimetry and EyeMovement Perimetry David E. Warren; Alice Xu; Andrew Papendieck; Matthew J. Thurtell; Michael Wall View Presentation 109. DR: Clinical Research I Moderator(s): Jennifer Sun (Joslin Diabetes Center) and Taraprasad Das (LV Prasad Eye Institute) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 190 - D0001. Choroidal thickness in diabetic retinopathy: the role of anti-VEGF therapy Inês Laíns; João Figueira; Ana Rita Santos; Alda Baltar; Miguel Costa; Sandrina Nunes; Cláudia Farinha; Rita Pinto; José Henriques; Rufino Silva View Presentation 191 - D0002. Comparison of Clinical Results of Pattern Scan Laser Versus Conventional Panretinal Photocoagulation in Proliferative Diabetic Retinopathy Tae Gon Lee; Judy E. Kim; Dongwon Lee; Jung Il Han; Joo Yeon Kim; Min Kyung Kim; Young-suk Chang View Presentation 192 - D0003. Retinal Vaculopathy in the Morbidly Obsese Tamara R. Vrabec; Tatiana C. Franco; Christopher Still; Craig Wood; Vincent F. Baldassano View Presentation 193 - D0004. Fundus Photographs (FP) versus Multicolor Spectralis (McS) for the Detection of Macular Hard Exudates in Diabetic Patients Screened Positive for Maculopathy Sergio Pagliarini; Elisa Carini; Mariano Cozzi View Presentation 194 - D0005. Is Peripheral Retinal Ischemia Associated with Systemic Atherosclerosis? Ashley M. Speilburg; Shaun Ittiara; Yi Pang; Danielle F. Leong; Ravi D. Patel; Leonard V. Messner; Seenu M. Hariprasad View Presentation 195 - D0006. Quantitative Evaluation of Perifoveal Capillary Network in Young Diabetes Mellitus Type I Patients Zoi Kapsala; Aristofanis Pallikaris; Vasileia Maniadi; Vassiliki Louvari; Dimitrios Mamoulakis; Miltiadis K. Tsilimbaris View Presentation 196 - D0007. Retinal arterial and venous oxygen saturation is altered in diabetic patients with and without retinopathy Bahram Khoobehi; Kim A. Firn; Reinoso Maria; O'Sullivan Patrick; James M. Beach; Amol Sura; John F. Green View Presentation 197 - D0008. Spectral-domain optical coherence tomographic findings of tractional macular elevation in eyes with proliferative diabetic retinopathy Kwang-Soo Kim; Rebecca Kim; Yu Cheol Kim View Presentation 198 - D0009. Effectiveness of prophylactic intravitreal bevacizumab injection in preventing complications after vitrectomy for proliferative diabetic retinopathy Kinya Tsubota; Yoshihiro Wakabayashi; Shunichiro Ueda; Yoshihiko Usui; Jun Suzuki; Hiroshi Goto View Presentation 199 - D0010. Assessment of retinal perfusion using ultra wide filed (UWF) imaging in patients with diabetic retinopathy treated with intravitreal bevacizumab (IVB) Shulamit Schwartz; Scott Oliver; Regina Victoria; Ramanath Bhandari; Naresh Mandava; Hugo Quiroz-Mercado View Presentation 200 - D0011. EasyScan miotic staging of diabetic retinopathy compared with ophthalmoscopic fundus examination simonetta guidelli guidi; Mariachiara Morara; Chiara Veronese; Carlo Torrazza; Francesco Pichi; Antonio P. Ciardella View Presentation 201 - D0012. Retinal Microglia Activity Mirrors the Progression of Diabetic Retinopathy. An in vivo Spectral Domain OCT Study Giulia Midena; Silvia Bini; Marianna Berton; Raffaele Parrozzani; Stela Vujosevic; Edoardo Midena View Presentation 202 - D0013. Surgical and visual outcome and prognostic factors following vitrectomy in diabetic tractional retinal detachment Ayumi Usui; Masatoshi Kiyokawa; Toshiro Sakuma; Rei Ito; Nobuyuki Ebihara View Presentation 203 - D0014. Adaptive optics imaging of diabetic retinopathy Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 14 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Jonathan Benesty; Sarah Ayello-Scheer; Jose A. Sahel; Michel Paques View Presentation 204 - D0015. Choroidal circulation before and after panretinal photocoagulation using a Pattern Scanning Laser for Diabetic Retinopathy Naoko Onizuka; Kiyoshi Suzuma; Masafumi Uematsu; Yoshihisa Yamada; Takashi Kitaoka View Presentation 205 - D0016. A Randomized Trial Evaluating Intravitreal Ranibizumab or Intravitreal Saline for Vitreous Hemorrhage from Proliferative Diabetic Retinopathy Abdhish R. Bhavsar View Presentation 206 - D0017. Telemedicine for diabetic retinopathy screening: a pilot program for Italian hospitals Alessandro Invernizzi; Maurizio T. Bevilacqua; Mariano Cozzi; Carlo D. Bianchi; Alessandro Pagani; Mario V. Cigada; Giovanni Staurenghi View Presentation 207 - D0018. Serum uric acid and newly developed diabetic retinopathy in type 2 diabetes mellitus-a 3 years’ prospective study Shih-Hao Wang; Jong-Jer Lee; Hsi-Kung Kuo; I-Hui Yang View Presentation 208 - D0019. Intravitreal Bevacizumab for Post-Operative Vitreous Hemorrhage After Vitrectomy for Diabetic Retinopathy Kevin Ferenchak; Renaud Duval; Jack A. Cohen; Mathew MacCumber View Presentation 209 - D0020. Assessment of macular function using the SKILL card in adult patients with Type 2 Diabetes Kavita P. Dhamdhere; Marilyn E. Schneck; Wendy Lam; Shirin Barez; Marcus A. Bearse; Anthony J. Adams View Presentation 210 - D0021. Potential of Spectral Domain Optical Coherence Tomography in assessing new vessel activity in proliferative diabetic retinopathy Sara Vaz-Pereira; Dawn A. Sim; Pearse A. Keane; Javier Zarranz-Ventura; Rebecca Smith; Catherine A. Egan View Presentation 211 - D0022. Predictive Factors for the Progression of Diabetic Macular Ischemia Dawn A. Sim; Pearse A. Keane; Javier Zarranz-Ventura; Catey Bunce; Marcus Fruttiger; Praveen J. Patel; Adnan Tufail; Catherine A. Egan View Presentation 212 - D0023. Intravitreal Ranibizumab for Diabetic Macular Edema with Prompt vs Deferred Laser Treatment: 3-year Randomized Trial Results Presenter: Michael E. Rauser, M.D. for the Diabetic Retinopathy Clinical Research Network Michael E. Rauser View Presentation 213 - D0024. Is it safe to discharge stable R3 (proliferative diabetic retinopathy) patients to the community screening program? Guy S. Negretti; Gilli C. Vafidis View Presentation 214 - D0025. Front or Back?: Intracameral vs. Intravitreal Injection of Bevacizumab for Neovascular Glaucoma Larry Puthenparambil; Yu-Guang He View Presentation 215 - D0026. Educational and Personal Reminders to Improve Follow-Up to Vision Care in Patients with Diabetes: A Prospective, Randomized Trial Camila Zangalli; Ann P. Murchison; Nicole Hale; Yang Dai; Lisa A. Hark; Laura Pizzi; Benjamin Leiby; Philip P. Storey; Julia A. Haller View Presentation 216 - D0027. Post-operative hemorrhage after vitrectomy for proliferative diabetic retinopathy with or without pre-surgical intravitreal bevacizumab Sumihiro Kawano; Toshifumi Yamashita; Yasushi Sonoda; Keita Yamakiri; Taiji Sakamoto View Presentation 217 - D0028. Vitamin B Intervention in Non-Proliferative Diabetic Retinopathy Michael K. Smolek; Neil F. Notaroberto; Lisa Pradillo; Arley G. Jaramillo; Kaci Lee View Presentation 218 - D0029. Clinical Utility of Multifocal Pupillographic Objective Perimetry in Type 1 Diabetes Ted Maddess; Lauren J. Baker; Andrew C. James; Caitlin Coombes; Veronica Cheung ; Melody Melody Chiou; Maria Kolic; Christopher Nolan; Faran Sabeti View Presentation 219 - D0030. Contribution of Breakdown of Outer Blood-retinal Barrier (BOBRB) to Diabetic Macular Edema Weiye Li; Mansi Patel; Behnaz Rouhani; Raza Shah; Fang Wang; Liumei Hu; Yaprak B. Unver View Presentation 110. AMD, CL Moderator(s): John Nolan (Waterford Institute of Technology) and Imre Lengyel (UCL Institute of Ophthalmology) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 220 - D0065. The Number and Distribution of People with Age-Related Macular Degeneration Worldwide in 2020 and 2040: A Systematic Review and Hierarchical Bayesian Meta-Analysis Tien Y. Wong; Xiang LI; Xinyi Su; Gemmy C. Cheung; Ching-Yu Cheng View Presentation 221 - D0066. Prevalence, Pattern and Risk Factors for Asian Age-related Macular Degeneration in Chinese, Malays and Indians: the Singapore Epidemiology of Eye Disease Program Gemmy C. Cheung; Xiang LI; Ching-Yu Cheng; Ying Feng Zheng; Paul Mitchell; Jie Wang; Tien Y. Wong View Presentation 222 - D0067. Prevalence and Risk Factors for Age-Related Macular Degeneration in the Elderly Chinese Population in Taiwan:The Puzih Eye Study Chien-Hsiung Lai; Evelyn Jou Chen Huang; Chien Neng Kuo; Pei-Lun Wu; Ching-Lung Chen; Chau-Yin Chen; Yin-Chi King; Pei-Chen Wu View Presentation 223 - D0068. Risk Factors of Age-Related Macular Degeneration in Argentina Van C. Lansingh; Maria E. Nano; Marissa J. Carter; Kristen A. Eckert; Luciana Fiocca Vernengo; Luna D. Jose; Natalia S. Zarate; Hugo Nano; Clelia Crespo Nano; Joao M. Furtado View Presentation 224 - D0069. Increasing the fidelity of AMD prediction models using population data from three continents G H. Buitendijk; Elena Rochtchina; Chelsea E. Myers; Sudha K. Iyengar; Paul Mitchell; Johannes R. Vingerling; Jie Wang; Ronald Klein; Caroline C. Klaver View Presentation 225 - D0070. Dietary Fat and Age-related Macular Degeneration in a Multiethnic Asian population: The Singapore Prospective Study Program Kumari Neelam; Huang Huiqi; Salome Rebello; E Shyong Tai; Jeannette Lee; Rob M. vanDam; Gemmy C. Cheung; Ching-Yu Cheng; Tien Yin Wong Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 15 sur 222 View Presentation 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 226 - D0071. Data-Driven Pattern Analysis of Dietary Items in Relation to Age-Related Macular Degeneration Amirul Islam; Elaine W. Chong ; Allison M. Hodge; Robyn H. Guymer; Khin Zaw Aung; Galina A. Makeyeva; Dallas R. English; Graham G. Giles; Paul N. Baird; Liubov D. Robman View Presentation 227 - D0072. Dietary Omega-3 Fatty Acids, Other Fat Intake, Genetic Susceptibility and Progression to Incident Geographic Atrophy Robyn Reynolds; Bernard Rosner; Johanna M. Seddon View Presentation 228 - D0073. Attenuation of Genetic Risk for Age-Related Macular Degeneration by Healthy Diets and Lifestyles Kristin J. Meyers; Zhe Liu; Barbara A. Blodi; Elizabeth J. Johnson; Rob Igo; Gloria E. Sarto; Lesley Tinker; Sudha K. Iyengar; Julie A. Mares View Presentation 229 - D0074. Complement factor B (CFB) polymorphisms and early and late age-related macular degeneration in the EUREYE Study Astrid E. Fletcher; Reecha Sofat; Usha Chakravarthy; Paulus T. de Jong; Mati Rahu; Jesus Vioque; Johan H. Seland; Fotis Topouzis; Gisele Soubrane View Presentation 230 - D0075. Effects of Cataract Surgery and Polymorphisms in CFH and ARMS2 on the risk of Age-related Macular Degeneration Chee Wai Wong; Tien Y. Wong; Jiemin Liao; Gemmy C. Cheung; Chiea Chuen Khor; Eranga N. Vithana; Paul Mitchell; Jie Wang; Tin Aung; Ching-Yu Cheng View Presentation 231 - D0076. The Genetics of Age-Related Maculopathy II (GARM II) study: an interim analysis Van Lam; Maria Carolina Ortube; Yvette Conley; Daniel E. Weeks; Ariadna Martinez; Nelson J. Aguilar; Victor Andon; Orlando Machuca; Angela Su; Michael B. Gorin View Presentation 232 - D0077. Stroke Risk in Advance Macular Degeneration from AREDS Data Set Lawrence J. Ulanski; Thasarat S. Vajaranant; Charlotte E. Joslin View Presentation 233 - D0078. Prevalence and Risk Factors of Age-related Macular Degeneration in Korean Population Sang Jun Park; Se Joon Woo; Kyu Hyung Park View Presentation 234 - D0079. C-reactive protein levels and the risk for developing age related macular degeneration in the National Health and Nutrition Examination Survey 2005-2008 Diego T. Barbosa; Sophia Wang; Shan C. Lin View Presentation 235 - D0080. Modeling the Risks of Age-related Macular Degeneration and its Predictive Comparisons in a Population in South India Krishnaiah Sannapaneni; Bapi Rajiu Surampudi; Jill E. Keeffe View Presentation 236 - D0081. Factors associated with early age-related macular degeneration: The Korea National Health and Nutrition Examination Survey 2008-2010 Kyungsik Lee; Tyler Hyung Taek Rim; Christopher S. Lee; SungChul lee View Presentation 237 - D0082. Assocation of Cotinine Level to Self Reported Nicotine Use and ARMD Mark W. Swanson View Presentation 238 - D0083. Qualitative Visual Symptoms in Age-Related Macular Degeneration Ray Gariano; Anne M. Hanneken View Presentation 239 - D0084. Periodontal Disease and Age-related Macular Degeneration Sushant Wagley; Rama A. Salhi; Kyle Marra; Jorge G. Arroyo View Presentation 240 - D0085. Determinants of macular pigment optical density in subjects at high risk for age-related macular degeneration: the LIMPIA Study Marie-Noelle Delyfer; Marie B. Rougier; Catherine Creuzot-Garcher; Hélène Savel; Geneviève Chêne; Cecile Delcourt; Jean-Francois Korobelnik View Presentation 241 - D0086. Drusen Characteristics, Retinal Pigmentary, and Visual Acuity Changes associated with 10 year Progression Rates to Intermediate and Advanced Age-Related Macular Degeneration in the Age-Related Eye Disease Study (AREDS) Emily Y. Chew; Traci E. Clemons; Elvira Agrón; Frederick L. Ferris View Presentation 242 - D0087. Risk Factors Associated with Earlier Age of Onset of Wet Age-related Macular Degeneration Yara T. Lechanteur; Patrick L. van de Camp; Joannes M. Groenewoud; Anneke I. Den Hollander; B. Jeroen Klevering; Carel B. Hoyng View Presentation 243 - D0088. Visual acuity outcomes after cataract surgery in patients with age-related macular degeneration in the Age-Related Eye Disease Study 2 (AREDS2) Benjamin P. Nicholson; Nancy Huynh; Elvira Agrón; Traci E. Clemons; Emily Y. Chew View Presentation 244 - D0089. Pulmonary Function, Respiratory Disease and the Incidence of Early and Late Age-Related Macular Degeneration: the Beaver Dam Eye Study Chelsea E. Myers; Barbara E. Klein; Sudha K. Iyengar; Theru A. Sivakumaran; Kristine E. Lee; Ronald E. Gangnon; Ronald Klein View Presentation 245 - D0090. Age-related macular degeneration and mortality in AREDS: the effect of sex and time Charlotte E. Joslin; Thasarat S. Vajaranant; Lawrence J. Ulanski View Presentation 246 - D0091. Predicting Non-response to Ranibizumab in Patients with Neovascular Age-related Macular Degeneration Freekje van Asten; Maroeska M. Rovers; Yara T. Lechanteur; Dzenita Smailhodzic; Philipp S. Muether; Anneke I. Den Hollander; Sascha Fauser; Carel B. Hoyng; Gert Jan van der Wilt; B. Jeroen Klevering View Presentation 247 - D0092. MULTICENTER RETROSPECTIVE STUDY OF AMD IN SPAIN Ricardo P. Casaroli-Marano; Roberto Gallego-Pinazo; Clemencia Torrón FernándezBlanco ; Marta S. Figueroa; Begoña Pina Marín; Gustavo Fernández-Baca Vaca; Antonio Piñero-Bustamante; Juan Donate López; Jose Garcia-Arumi; Jordi Farres Martí View Presentation 248 - D0093. Does Treatment of Hypertension Affect the Risk of Developing Macular Degeneration or Disease Progression? Partho S. Kalyani; Taylor S. Blachley; David N. Zacks; Joshua D. Stein View Presentation 249 - D0094. Systemic adverse events after antiangiogenic therapy in clinical trials comparing Bevacizumab and Ranibizumab Jose Lorenzo Carrero; Alexandros Deligiannidis View Presentation 250 - D0095. Outcomes of Second eye Versus First eye in Patients Treated with Ranibizumab for Bilateral Neovascular Age Related Macular Degeneration Ramu Muniraju; Jayashree Ramu; Sobha Sivaprasad View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 16 sur 222 8:30 AM - 10:15 AM 251 - D0096. « DODMLA » : Organized screening of age-related macular degeneration by delayed reading of retinophotography Flore De Bats; Christiane Vannier Nitenberg; Bruno Fantino; Laurent Kodjikian View Presentation 111. Macular Edema Moderator(s): Victor Chong (Oxford University Hospitals) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 252 - D0097. Correlations Between Functional and Structural Changes in Treatment of Macular Edema Secondary to Branch Retinal Vein Occlusion Gokcen Gokce; Gungor Sobaci; Ali Hakan Durukan; Fazil Cuneyt Erdurman View Presentation 253 - D0098. Consecutive macular edema and visual outcome in branch retinal vein occlusion Hyo sung Yoon; In Won Park; Soon Il Kwon; Sung uk Baek View Presentation 254 - D0099. Treatment of Macular Edema (secondary to vein occlusion) with Dexamethasone Implant (Ozurdex) Nabil Jabbour; Frank Ruda; Adel s. Wahba View Presentation 255 - D0100. Predictors of Short-Term Visual Outcome After Dexamethasone (700mcg) Intravitreal Therapy For Vein Occlusions Rupal Morjaria; Magdalena Sinczak; Victor Chong View Presentation 256 - D0101. Optical Coherence Tomography Predictors of Visual Outcome in Macular Edema Salma Radwan; Sohini RoyChowdhury; Julian Tokarev; Helen F. Roemhild; Keshab K. Parhi; Dara D. Koozekanani View Presentation 257 - D0102. Assessment of Metamorphopsia in Patients with Central Serous Chorioretinopathy Ju Byung Chae; Moses Kim; Sungmin Hyung View Presentation 258 - D0103. Evaluation of Aqueous Flare values in Patients with Cystoid Macular Edema after Cataract Surgery Lebriz Ersoy; Albert Caramoy; Tina Ristau; Bernd Kirchhof; Sascha Fauser View Presentation 259 - D0104. Optical Coherence Tomography Assisted Enhanced Depth Imaging of Central Serous Chorioretinopathy Lihong Yang; Jost B. Jonas; Wen Bin Wei View Presentation 260 - D0105. Impact on Intraocular Pressure (IOP) after 20mg Intravitreal Triamcinolone Acetonide (IVTA) Injections when utilizing prophylactic IOP-lowering therapy Payam Amini; Giulio Barteselli; William Freeman View Presentation 261 - D0106. Intravitreal Methotrexate for different inflammatory retinal conditions Egbert Matthe; Dirk Sandner; Lutz E. Pillunat View Presentation 262 - D0107. Results of Intravitreal Dexamethasone Implant 0.7mg (Ozurdex) in noninfectious posterior uveitis Yew Chong Yap; Thomas Papathomas; Kamal Ahmed View Presentation 263 - D0108. Treatment Outcomes of Cystoid Macular Edema in Patients with Boston Type I Keratoprosthesis Randee C. Miller; Kaitlyn M. Wallace; Joshua H. Hou; Clement C. Chow; Jose De la Cruz; Maria S. Cortina; Felix Y. Chau View Presentation 112. Animal Models of Disease Moderator(s): Xi-Qin Ding (Univ Oklahoma Hlth Sciences Ctr) and Timothy Kern (Case Western Reserve Univ) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details View Session Details 264 - D0213. Identification of a novel genetic model for retinal neovascularization Mariacarmela Allocca; Barrett D. Leehy; Joseph A. White; Leo A. Kim; Magali SaintGeniez; Pascal Escher; Dean Eliott; Eric A. Pierce; Margaret M. DeAngelis; Neena B. Haider View Presentation 265 - D0214. Survey of Common Genetic Eye Diseases in Mouse Strains Bo Chang; Ron Hurd; Jieping Wang; Patsy M. Nishina View Presentation 266 - D0215. Up-regulation Of Growth Hormone Releasing Hormone (GHRH) Receptors In The Ischemic Retina Sagar Patel; Folami Lamoke; Chaunte E. Stampley; Babak Baban; Maritza Romero; Rudolf Lucas; Norman L. Block; Andrew Schally; Manuela Bartoli View Presentation 267 - D0216. Determination of intraocular oxygen tension and temperature in retinal diseases Young-Hoon Park; So-Yoon Kim; Ji-Wook Yang View Presentation 268 - D0217. Choroidal Thickness of Branch Retinal Vein Occlusion Kenji Sogawa; Taiji Nagaoka; Tomofumi Tani; Ichiro Tanano; Akitoshi Yoshida View Presentation 269 - D0218. Downregulation of aldehyde detoxification enzymes in the diabetic retina Rosie Mcdowell; Timothy M. Curtis; Graham McGeown View Presentation 270 - D0219. TXNIP regulates neurotrophic factor expression and neuronal injury in early diabetic retinopathy Lalit P. Singh; Takhellambam S. Devi View Presentation 271 - D0220. Post-Translational Processing and Expression of Synaptophysin is Altered by Reduced α-Mannosidase Activity in Diabetes Alistair J. Barber; Travis S. D'Cruz; Brittany N. Weibley View Presentation 272 - D0221. Autophagy in Modified LDL-induced Pericyte Loss in Diabetic Retinopathy Dongxu Fu; Shihe Yang; Mingyuan Wu; Mei Du; Junping Chen; Kenneth Wilson; Timothy J. Lyons View Presentation 273 - D0222. Profiling miRNAs in a hyperglycemic and hypoinsulinemic Ins2Akita mouse model Audrey Giocanti-Auregan; Lisa Ahn; Javier Sancho-Pelluz; Stephen H. Tsang; Szilard Kiss; Mark Rosenblatt; Thomas Tuschl; John T. Pena; Donald J. D’Amico View Presentation 274 - D0223. Influence of Proliferative Diabetic Retinopathy Aqueous in Causing Defective CD34 cells Sankarathi Balaiya; Maria B. Grant; K V Chalam View Presentation 275 - D0224. Differential Distribution of Optic Nerve Lipids in the DBA/2J Mouse Model of Glaucoma Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 17 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Dhananjay Sakrikar; David M. Anderson; Jeffrey M. Spraggins; Wendi S. Lambert; Kevin L. Schey; David J. Calkins View Presentation 276 - D0225. In-Office Vitreous Sampling shows that Levels of MMP-9 Correlate with the Severity of Proliferative Diabetic Retinopathy Ann O. Igbre; Stephanie M. Ecker; Joshua C. Hines; Bert M. Glaser View Presentation 277 - D0226. Notch signaling misregulation in retinal pericytes exposed to high glucose Joseph F. Arboleda-Velasquez; Alexandra M. James; Vincent A. Primo; Mark J. Graham; Patricia A. D'Amore View Presentation 278 - D0227. A transcriptomic Approach to Refine the Primary Locus of a Canine Oligogenic Cone-Rod Dystrophy Gautami Das; Anand Swaroop; Matthew Brooks; Gustavo D. Aguirre; Keiko Miyadera View Presentation 279 - D0228. Therapeutic Effect of PPARα Agonist on Pericyte Loss in Diabetic Retinopathy Lexi Ding; Rui Cheng; Yang Hu; Jian-Xing Ma View Presentation 280 - D0229. IGF-1R EXPRESSION IN AN OXYGEN-INDUCED RETINOPATHY (OIR) MODEL Maria C. Sanchez; Valeria E. Lorenc; Luna D. Jose; Gustavo A. Chiabrando View Presentation 281 - D0230. Photoreceptors are a main generator of superoxide in retinas of diabetic mice Timothy S. Kern; Yunpeng Du; Krzysztof Palczewski; Bruce A. Berkowitz View Presentation 282 - D0231. An Xbp1-GFP-rhodopsin reporter transgene for assessing ER stress in Xenopus laevis models of retinitis pigmentosa Beatrice M. Tam; Jonathan H. Lin; Orson L. Moritz View Presentation 283 - D0232. Analysis of microRNA expression changes following explantation of bovine RPE T. Michael Redmond; Cynthia Jaworski; William Samuel; R K. Kutty; Todd Duncan; Toral P. Parikh View Presentation 284 - D0233. Accumulated Increase of mtDNA Damage Contribute to Progressive Loss of RGC in a Rat Model of Glaucoma Jihong Wu; Shenghai Zhang View Presentation 285 - D0234. Conditional mutant analysis of Dnmts in murine retinal ganglion cells Raymond Enke; Zhiyong Yang; William W. Hauswirth; Sanford L. Boye; Vince Chiodo; Donald J. Zack; Shannath L. Merbs View Presentation 286 - D0235. Adenosine triphosphate (ATP) Signaling Pathways Trigger Glial Activation in the Mouse Retina Caitlin E. Mac Nair; Cassandra Schlamp; Robert W. Nickells View Presentation 287 - D0236. Whirlin proteins localize at the outer limiting membrane and subapical region of zebrafish retina Sabrina Toro; Jennifer B. Phillips; Monte Westerfield View Presentation 288 - D0237. Age-related Upregulation of MicroRNA miR-34a In the Mouse Retina and RPE/choroid Zeljka Smit-McBride; Leonard M. Hjelmeland View Presentation 289 - D0238. The Rat Optic Nerve Head Filamentous Actin Cytoskeleton And Response To Experimental Intraocular Pressure Elevation Shandiz Tehrani; Elaine C. Johnson; William Cepurna; Matthew R. Bald; John C. Morrison View Presentation 290 - D0239. Mechanistic insights into the link between impaired cholesterol elimination and vascular abnormalities in mouse retina Aicha Saadane; Casey Charvet; Natalia Mast; Wenchao Zheng; Timothy S. Kern; Suber Huang; Irina A. Pikuleva View Presentation 291 - D0240. THERAPEUTIC EFFICACY OF MELATONIN IN REDUCING RETINAL DAMAGE IN AN EXPERIMENTAL MODEL OF EARLY TYPE 2 DIABETES IN RATS Ruth E. Rosenstein; Melina P. Bordone; Monica S. Chianelli; María I. Keller Sarmiento; Damian Dorfman; Magdalena Miranda; Ezequiel M. Salido View Presentation 292 - D0241. FOXOs in the Mouse Visual System Jullia A. Rosdahl; Guorong Li; Jianming Qiu; Pedro Gonzalez; Pratap Challa View Presentation 293 - D0242. Characterization of Genome-Wide DNA Methylation in the Mouse Retina Verity F. Oliver; Jun Wan; Saurabh Agarwal; Donald J. Zack; Jiang Qian; Shannath L. Merbs View Presentation 294 - D0243. Expression Patterns Of Histone Deacetylases In Murine and Chick Optic Nerve During Development Mahesh Shivanna; Teri L. Belecky-Adams View Presentation 295 - D0244. Ablation of the X-linked Retinitis Pigmentosa 2 (Rp2) gene in mice results in opsin mistrafficking and photoreceptor degeneration Linjing Li; Naheed W. Khan; Toby Hurd; Amiya K. Ghosh; Christiana Chang; Robert S. Molday; John R. Heckenlively; Anand Swaroop; Hemant Khanna View Presentation 296 - D0245. ASSESSMENT OF RETINAL STRUCTURE FOLLOWING REPEATED LIGHT EXPOSURE IN THE LIGHT SENSITIVE T4R RHODOPSIN MUTANT DOG RETINA Simone Iwabe; Kendra McDaid; Gustavo D. Aguirre; William A. Beltran View Presentation 297 - D0246. Gene expression changes under cyclic mechanical stretching in rat retinal glial (Müller) cells Xin Wang; Gezhi Xu View Presentation 298 - D0247. A retinal phenotype in Usher IIIA mouse models Rachel M. Stupay; W Clay Smith; Wen-Tao Deng; Ping Zhu; William W. Hauswirth; Astra Dinculescu View Presentation 113. ipRGCs and Melanopsin Moderator(s): Felice Dunn (University of Washington) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM View Session Details 299 - D0292. A Histopathologic and Morphometric Analysis of Degenerating Melanopsin Retinal Ganglion Cells in Alzheimer’s Disease Fred N. Ross-Cisneros; Chiara La Morgia; Billy X. Pan; Jens Hannibal; Valerio Carelli; Alfredo A. Sadun View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 18 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 300 - D0293. M1 melanopsin ganglion cells are the most injury-resistant ganglion cell subtype following axotomy Luis Perez de Sevilla Muller; Allison Sargoy; Allen Rodriguez; Nicholas Brecha View Presentation 301 - D0294. Melanopsin mediates dopamine neuron light-evoked responses in rd1 retinas Cameron Atkinson; Dao-Qi Zhang View Presentation 302 - D0295. µ-opioid receptor mediated modulation of ipRGCs Shannon K. Gallagher; Paul Witkovsky; Puneet Sodhi; Andrew T. Hartwick; Jozsef Vigh View Presentation 303 - D0296. Adenosine A1 Receptor-Mediated Neuromodulation of Rat ipRGC Light Responses Puneet Sodhi; Andrew T. Hartwick View Presentation 304 - D0297. Two Types of M1 Melanopsin Ganglion Cell in the Rabbit Retina Regina D. Nobles; Stephen C. Massey View Presentation 305 - D0298. Dendritic Stratification of Intrinsically Photosensitive Retinal Ganglion Cells During Postnatal Retinal Development Simon Pan; Samer Hattar; Tiffany M. Schmidt View Presentation 306 - D0299. ipRGC light response characteristics change from post-natal to adult primarily between P8 and P15 in mice Timothy Sexton; Russell N. Van Gelder View Presentation 307 - D0300. Role for melanopsin in alpha retinal ganglion cell physiology and contrast detection Tiffany M. Schmidt; Nazia M. Alam; Shan Chen; Paulo Kofuji; Wei Li; Glen T. Prusky; Samer Hattar View Presentation 308 - D0301. Whole-cell recordings of dark-adapted mouse ipRGCs Xiwu Zhao; Kwoon Y. Wong View Presentation 309 - D0302. Determining the Retinal Circuitry that drives Circadian Photoentrainment Melissa E. Simmonds; Shih-Kuo Chen; Samer Hattar View Presentation 310 - D0303. ipRGCs mediate ipsilateral pupil constriction Alan Rupp; Tiffany M. Schmidt; Kylie Chew; Benjamin Yungher; Kevin K. Park; Samer Hattar View Presentation 311 - D0304. Gap Junctions Propagate Melanopsin-like Responses among Ganglion Cells in Efemp1R345W Mice Frederick R. Blodi; Malini Shankar; Pratibha Singh; Robert F. Mullins; Michael P. Andrews; Edwin M. Stone; Stewart Thompson; Steven F. Stasheff View Presentation 114. AMD Mechanisms: Choroid and RPE View Session Details Moderator(s): Tailoi Chan-Ling (University of Sydney) and Andrew Lotery (University of Southampton) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 312 - D0348. Compelling Evidence Of Lymphangiogenesis And Lymphatic Vessels In The Developing And Adult Human Choroid Tailoi Chan-Ling; Louise Baxter; Ping Hu; Samuel J. Adamson; Frank Arfuso; Michele C. Madigan; Mark E. Koina View Presentation 313 - D0349. Safety and Functionality of a Retinal Pigment Epithelium Monolayer Transplantation derived from Human Embryonic Stem Cells in Yucatan Mini-Pigs Michael J. Koss; Ramiro Ribeiro; Rodrigo A. Brantfernandes; Aldo A. Oregon-Miranda; Padmaja B. Thomas; Biju B. Thomas; Danhong Zhu; Gerald J. Chader; David R. Hinton; Mark S. Humayun View Presentation 314 - D0350. An in vitro 3-D cell culture model for studying pathomechanisms in AMD Audra M. Shadforth; Damien G. Harkin; Traian V. Chirila; Anthony Weiss; Dietmar W. Hutmacher; Beatrix K. Feigl View Presentation 315 - D0351. Inflammasomes in human eyes with AMD and mouse retinas with focal retinal degeneration Chi-Chao Chan; DeFen Shen; Yujuan Wang; Xi K. Chu; Mones S. Abu-Asab; Jingsheng Tuo View Presentation 316 - D0352. An Improved Method to Study Circulating Vascular Progenitor Cells (VPC’s) in Patients with Neovascular Age-Related Macular Degeneration (nvAMD) Timothy Catchpole; Karl G. Csaky View Presentation 317 - D0353. Characterization of HtrA1 Promoter in Patients with Exudative Age-Related Macular Degeneration Daisuke Iejima; Toru Noda; Atsushi Mizota; Takeshi Iwata View Presentation 318 - D0354. Impairment of the ubiquitin function in retinal pigment epithelium results in AMD-like lesions in mice Fu Shang; Qingning Bian; Janis Lem; Allen Taylor; Donald Smith; Paulo Pereira View Presentation 319 - D0355. Involvement of Angiopoietin-like 2 in Laser-induced Choroidal Neovascularization Manabu Hirasawa; Motoyoshi Endo; Mamoru Kamoshita; Seiji Miyake; Toshio Narimatsu; Norihiro Nagai; Kazuo Tsubota; Yoko Ozawa View Presentation 320 - D0356. Aged Mice Manifest More Mature Neovascularization in a Novel Model of Injury-Induced Angiogenesis Priyatham S. Mettu; Tiffany Pridgen; M. Grazia Spiga; Peter Saloupis; Scott W. Cousins View Presentation 321 - D0357. Interleukin-18 induced retinal pigment eithelium cell death, but did not suppress choroidal neovascularization in mice Ryo Ijima; Hiroki Kaneko; Shu Kachi; Hiroko Terasaki View Presentation 322 - D0358. Differential expression patterns of Semaphorin 3F in the murine and human retina and its role in choroidal neovascularization Anima D. Buehler; Nicholas Sitaras; Sandra Favret; Jean-Sebastien Joyal; Gottfried Martin; Michael Klagsbrun; Hansjürgen T. Agostini; Lois E. Smith; Przemyslaw Sapieha; Andreas Stahl View Presentation 323 - D0359. A SIMPLE MODEL FOR CREATION OF CHORIORETINAL NEOVASCULARIZATION (CNV) IN PIGMENTED MICE USING INDIRECT DIODE LASER Elite Bor Shavit; Tami Livnat; Mor Dachbash; Yael Nisgav; Opher Kinrot; Dov Weinberger View Presentation 324 - D0360. Aryl-hydrocarbon receptor plays a role in choroidal neovascularization by Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 19 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM regulating endothelial migration and tube formation Mayur Choudhary; Amanda Bednar; Peter Saloupis; Peng Hu; Goldis Malek View Presentation 325 - D0361. Metabolic syndrome triggered by fructose feeding exacerbated laserinduced choroidal neovascularization in the rat Magalie THIERRY; Bruno Pasquis; Niyazi Acar; Stéphane Grégoire; Valérie Febvret; Ségolène Gambert-Nicot; Alain M. Bron; Catherine P. Garcher; Lionel Bretillon View Presentation 326 - D0362. Loss of Cathepsin B and Z reduces matrix invadosome formation, endothelial sprouting and CNV area in mice Stefanie Berger; Anima D. Buehler; Fee Werner; Gottfried Martin; Hong Han; Daniel Boehringer; Gunther R. Schlunck; Hansjürgen T. Agostini; Thomas Reinheckel; Andreas Stahl View Presentation 327 - D0363. Metallothionein-3 is essential for vascular endothelial growth factor induction in a mouse model of choroidal neovascularization (CNV) Young Hee Yoon; Jeong A Choi; Jong-uk Hwang; kyung sook cho; Jae-Young Koh View Presentation 328 - D0364. CCR2-dependent recruitment of VEGF-producing macrophages promotes neovascularization after laser injury Torsten Andreas Krause; Anne F. Alex; Daniel R. Engel; Christian Kurts; Nicole Eter View Presentation 329 - D0365. In vivo release and retinal safety of intravitreal implants of thalidomide in rabbit eyes and antiangiogenic effect on the chorioallantoic membrane Murilo M. Oliveira; Silvia Fialho; Marcela Souza; Pedro Souza; Gustavo Fulgêncio; Antonio Haddad; Armando S. Cunha; Andre Messias; Rodrigo Jorge View Presentation 330 - D0366. Exploring Potential Differences in the Cell Energy Metabolism of Retinal Pigment Epithelial (RPE) Cell Culture Models Peng Hu; Alfredo Caro-Maldonado; Jeffrey Rathmell; Goldis Malek View Presentation 331 - D0367. Long-term multiple A2E treatment leads to melanization of ARPE19 cells Eugenia Poliakov; Natalia V. Strunnikova; Bianca Martinez; Toral P. Parikh; Brian P. Brooks; T. Michael Redmond View Presentation 332 - D0368. Co-Localization of an In Vivo Retinal Pigment Epithelial Cell Death Imaging Probe in a Mouse Model of Acute Double-Stranded RNA Toxicity Chad Jackson; Kabhilan Mohan; Yoshio Hirano; Andre Berner; Dingyuan Lou; Jennifer L. Brown; Jayakrishna Ambati; Mark E. Kleinman View Presentation 333 - D0369. The Analysis of Sorting Elements of ARMS2 Suggests a Novel Protein Export Mechanism Elod Kortvely; Lili Feng; Stefanie M. Hauck; Jennifer Behler; Matteo Gorza; Karsten Boldt; Marcel Blindert; Marius Ueffing View Presentation 334 - D0370. The role of VEGFR-3 in the pathogenesis of choroidal neovascularization in age-related macular degeneration Takeshi Yoshida; Shikun He; Mizuki Kitamura; Christine Spee; Stephen J. Ryan; David R. Hinton View Presentation 335 - D0371. Amyloid β enhances expression and activity of HTRA1 in retinal pigment epithelial cells, a mechanism of wet age-related macular degeneration development from drusen Jiying Wang; Kyoko Ohno-Matsui; Ikuo Morita View Presentation 336 - D0372. Mapping Angiogenesis on Choroidal Membranes of a Murine Laserinduced CNV Model Helder Andre; Monica Aronsson; Anders P. Kvanta View Presentation 337 - D0373. Genotype phenotype correlations in Fibulin 5 associated macular degeneration Heather A. Thomson; Cheryl A. Hawkes; Charles Pierce; Andrew J. Lotery View Presentation 338 - D0374. Anti-histamine receptor 4 therapy inhibits choroidal neovascularization in mice Hiroki Kaneko; Ryo Ijima; Shu Kachi; Hiroko Terasaki View Presentation 339 - D0375. Choroidal Vascular Pathology in Human Eyes with the Y402H Allele of Complement Factor H Desi P. Schoo; Aditi Khanna; Kai Wang; Megan R. Streb; Edwin M. Stone; Robert F. Mullins View Presentation 340 - D0376. Exosomes Released From Retinal Astroglial Cells (RACs) Contain AntiAngiogenic Components That Can Suppress Active Vessels In a Laser-induced CNV Model Amir R. Hajrasouliha; Guomin Jiang; Wei Wang; Henry J. Kaplan; Hui Shao View Presentation 341 - D0377. Prostones Attenuate the TNFα-Induced Breakdown of the Epithelial Barrier in Retinal Pigment Epithelial Cells John Cuppoletti; Jayati Chakrabarti; Danuta Malinowska; Rita Rosenthal; Damon Kim; Anja Fromm; Michael Fromm; Birgit Roerig; Malarvizhi Durai; Ryuji Ueno View Presentation 342 - D0378. Macrophage Activation by RPE-Derived Exosomes Yiqin Zuo; Zhen-Yang Zhao; Pei Xu; Bo Yu; Yan Chen; Jiyang Cai View Presentation 343 - D0379. Functional Interactions between Autophagy and Phagocytosis Pathways in ARPE-19 cells Pei Xu; Zhen-Yang Zhao; Bo Yu; Yiqin Zuo; Jiyang Cai; Yan Chen View Presentation 344 - D0380. Epigenetic Regulation of Eotaxin Expression in Human Retinal Pigment Epithelium Mark E. Kleinman; Andre Berner; Dingyuan Lou; Kabhilan Mohan; Chad Jackson; Jennifer L. Brown; Jayakrishna Ambati View Presentation 345 - D0381. Understanding The Role Of Fibulin 2, A Tyrosine-O-Sulfated Protein, In Vision Yogita Kanan; Dan E. Brobst; Muayyad R. Al-Ubaidi View Presentation 115. Retinal Prosthesis I Moderator(s): Mark Humayun (Doheny Eye Institute - USC) and Penelope Allen (CERA) 10:30 AM - 12:15 PM; 6E 10:30 AM - 10:45 AM 10:45 AM - 11:00 View Session Details 346. Extracellular recording of multiple retinal ganglion cells during epiretinal vs. subretinal electrical stimulation of isolated mouse retina with a high resolution stimulation device Eyal Margalit; Sylvie Sim; Robert Szalewski; Lee J. Johnson; Wallace B. Thoreson View Presentation 347. On Resolution of Photovoltaic Subretinal Prosthetics Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 20 sur 222 AM 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM Richard Smith; Georges A. Goetz; Keith Mathieson; James Loudin; Daniel V. Palanker; Alexander Sher View Presentation 348. Cortical Responses to Subretinal Photovoltaic Stimulation can be modulated Similarly to Light-Induced Visual Evoked Potentials Yossi Mandel; Georges A. Goetz; Daniel Lavinsky; Philip Huie; Keith Mathieson; Lele Wang; Theodore I. Kamins; Richard Manivanh; James Harris; Daniel V. Palanker View Presentation 349. Recent Results from Second Sight’s Argus® II Retinal Prosthesis Study Mark S. Humayun; Lyndon daCruz; Gislin Dagnelie; Paulo E. Stanga; Allen C. Ho; Robert J. Greenberg; David G. Birch; Jacque L. Duncan; Jose A. Sahel View Presentation 350. Electric Field Shaping Via Separatrices For Focused Electric Retinal Stimulation Via Retinal Implants Wolfgang Fink; Erich W. Schmid View Presentation 351. High-Frequency Electrical Stimulation Produces Differential Responses in ON and OFF Retinal Ganglion Cells Perry T. Twyford; Shelley I. Fried View Presentation 352. Holographic display system for photovoltaic retinal prosthesis Georges A. Goetz; Daniel V. Palanker; Tomas Cizmar View Presentation 116. CNS and Ocular Inflammation and Infection Moderator(s): Nisha Acharya (Univ of California - SF) and Bahram Bodaghi (Pitie Salpetriere Hospital) 10:30 AM - 12:15 PM; 606/607 10:30 AM - 10:45 AM 10:45 AM - 11:00 AM 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 353. HLA-B27 affects the gut microbiome of transgenic rats Phoebe Lin; Mary Bach; Aaron Y. Lee; Lakshmi Akileswaran; Joel D. Taurog; James T. Rosenbaum; Russell N. Van Gelder View Presentation 354. TL1A is a potent enhancer of IL-9 production and ocular immunopathogenicity by Th9 cells Cuiyan Tan; Francoise Meylan; Barbara P. Vistica; Richard Siegel; Igal Gery View Presentation 355. Idiopathic Intermediate Uveitis: A 25-year study of visual prognosis William R. Tucker; Elizabeth Graham; Philip I. Murray; Miles R. Stanford View Presentation 356. Clinical Profile, Treatment and Visual Outcome of Eales' Disease, Study of 500 Patients from South India Jyotirmay Biswas; Reesha Kr; Bikramjit Pal View Presentation 357. Prevalence of Anti-Retinal Autoantibodies in Women with Gynecological Cancers with and without Cancer Associated Retinopathy Grazyna Adamus; Dongseok Choi; Jade Schiffman View Presentation 358. Use of biologics in pediatric uveitis: changing treatment patterns Friederike Mackensen; Matthias D. Becker; Juergen Grulich-Henn; Thomas Lutz View Presentation 359. CAP-Syndrome: Response to Treatment With Canakinumab Manfred Zierhut; Bianka Sobolewska; Christoph M. Deuter; Deshka Doycheva; Jasmin Kuemmerle-Deschner View Presentation 117. Mechanisms in AMD Moderator(s): Catherine Bowes Rickman (Duke University Medical Center) and Mark Kleinman (Univ of Kentucky) 10:30 AM - 12:15 PM; 611-614 10:30 AM - 10:45 AM 10:45 AM - 11:00 AM 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 10:30 AM - 10:45 10:45 AM - 11:00 AM 11:00 AM - 11:15 AM View Session Details 360. The role of cell senescence, Epithelial-Mesenchymal Transition, and fibrosis in the generation of vicious inflammatory cycle between macrophages and retinal pigment epithelium Jun Yamada; Hiroki Hatanaka; kazuko asada; Kana Nakata; Junji Hamuro; Shigeru Kinoshita View Presentation 361. Retinal pigment epithelium cell-derived microparticles mediate oxidative stressinduced retinal cells dysfunction Pierre Hardy; Houda Tahiri; Chun Yang View Presentation 362. Cytotoxic Alu RNA accumulation in the RPE mediated by iron overload Bradley D. Gelfand; Mark E. Kleinman; Jayakrishna Ambati View Presentation 363. Endo-lysosome trafficking protects retinal pigment epithelial cells from complementmediated attack Aparna Lakkaraju; Kimberly A. Toops; Jin Xu View Presentation 364. Oxidative Stress Significantly Increases Expression of Inflammatory and Antioxidant Markers in Complement Factor H Deficient Mice Compared to Wild-Type Mice Terry Singhapricha; Una L. Kelly; Michael J. Landowski; Marybeth Groelle; Peter Saloupis; Catherine Bowes Rickman View Presentation 365. RPE-specific VEGF Deletion Induces Geographic Atrophy: a Long-term Study Liliana Paris; Toshihide Kurihara; Peter D. Westenskow; Stephen Bravo; Carli M. Wittgrove; Edith Aguilar; Martin Friedlander View Presentation 366. Pathological Role of RPE-derived microRNA Cluster miR17-92 in Subretinal Neovascularization Toshihide Kurihara; Peter D. Westenskow; Stephen Bravo; Mollie Friedlander; Edith Aguilar; Martin Friedlander View Presentation 118. Age-Related Macular Degeneration: Novel Markers and Risk Factors Moderator(s): Astrid Fletcher (London School of Hygiene & Tropical Med) and Amy Millen (University at Buffalo) 10:30 AM - 12:15 PM; 615-617 AM View Session Details View Session Details 367. The Incidence and Progression of Reticular Drusen: Findings from an Older Australian Cohort Nichole D. Joachim; Paul Mitchell; Elena Rochtchina; Ava G. Tan; Jie Jin Wang View Presentation 368. Inflammatory Markers and Age-related Macular Degeneration: Findings from an Older Cataract Surgical Cohort Jie Jin Wang; Calvin S. Fong; Elena Rochtchina; Ava G. Tan; Paul Mitchell View Presentation 369. Inflammatory and Oxidative Stress Markers and the 20-Year Cumulative Incidence of Age-related Macular Degeneration: the Beaver Dam Eye Study Ronald Klein; Chelsea E. Myers; Sudha K. Iyengar; Theru A. Sivakumaran; Karen J. Cruickshanks; Kristine E. Lee; Ronald E. Gangnon; Barbara E. Klein Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 21 sur 222 View Presentation 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 370. Association between vitamin D status and age-related macular degeneration (AMD) by complement factor H (CFH) Y402H genotype Amy E. Millen; Kristin J. Meyers; Zhe Liu; Corinne D. Engelman; Erin S. LeBlanc; Robert B. Wallace; Lesley Tinker; Sudha K. Iyengar; Julie A. Mares View Presentation 371. LIPC and LPL polymorphisms, age-related macular degeneration and plasma lutein and zeaxanthin: the Alienor Study Benedicte Merle; Cécilia Maubaret; Jean-Francois Korobelnik; Marie-Noelle Delyfer; Marie B. Rougier; jean-Charles Lambert; Philippe Amouyel; Joseph Colin; Pascale Barberger-gateau; Cecile Delcourt View Presentation 372. Intravitreal ranibizumab treatment of wet macular degeneration in SE Scotland – effect on blindness rates and 5 year follow up data Peter Cackett; Shyamanga Borooah; Mike Gavin; Dilys Oladiwura; V.Swetha E. Jeganathan View Presentation 373. Cost-effectiveness of ranibizumab and bevacizumab for neovascular age-related macular degeneration: 1 year IVAN results Chris Rogers; Helen A. Dakin; Sarah Wordsworth; Giselle Abangma; James Raftery; Simon P. Harding; Usha Chakravarthy; Andrew J. Lotery; Susan Downes; Barnaby C. Reeves View Presentation 119. Trabecular Meshwork I Moderator(s): Paul Russell (University of California Davis) and James Tan (Univ of Southern California) 10:30 AM - 12:15 PM; 618-620 10:30 AM - 10:45 AM 10:45 AM - 11:00 AM 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 374. Expression of ER Stress Markers in the Human Trabecular Meshwork Markus H. Kuehn View Presentation 375. Functional and Morphological Alterations Associated with Steroid-Induced Ocular Hypertension in Mice Darryl R. Overby; Jacques Bertrand; Ozan Tektas; Alexandra Boussommier Calleja; W Daniel Stamer; C R. Ethier; David F. Woodward; Elke Luetjen-Drecoll View Presentation 376. Effect of transforming growth factor beta-2 signaling and gremlin induction on fibronectin, ocular hypertension, and optic nerve damage in mice Colleen M. McDowell; Tomi Luan; Iok-Hou Pang; Robert J. Wordinger; Abbot F. Clark View Presentation 377. Integrins Modulate Phagocytosis in Human Trabecular Meshwork (TM) Cells Debjani Gagen; Ross W. Clark; Paloma B. Liton; Donna M. Peters View Presentation 378. Regulation of Cell Plasticity and Fibrogenic Activity in Trabecular Meshwork by Rho/Rho kinase Signaling in the Context of Aqueous Humor Outflow Homeostasis Padmanabhan P. Pattabiraman; Rupalatha Maddala; Vasanth Rao View Presentation 379. Elevated stiffness of cultured glaucomatous Schlemm’s canal (SC) cells correlates with impaired pore formation Mark Johnson; Ryan M. Pedrigi; Rocio Vargas-Pinto; Ritika Gupta; Sietse T. Braakman; C R. Ethier; Kristin M. Perkumas; W Daniel Stamer; Darryl R. Overby View Presentation 380. Monolayer traction forces of Schlemm’s canal endothelial cells Enhua H. Zhou; W Daniel Stamer; Chan Young Park; Kristin M. Perkumas; James P. Butler; Mark Johnson; Jeffrey J. Fredberg View Presentation 120. Accommodation and Presbyopia Moderator(s): Susana Marcos (Consejo Sup de Investig Sci) and Adrian Glasser (University of Houston) 10:30 AM - 12:15 PM; TCC LL 4/5 10:30 AM - 10:45 AM 10:45 AM - 11:00 AM 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 10:30 AM - 10:50 10:50 AM - 11:05 AM 11:05 AM - 11:20 AM View Session Details 381. Three-Dimensional Biometric Measurements of Accommodation Using Full-EyeLength Swept-Source OCT Ireneusz Grulkowski; Jonathan J. Liu; Benjamin Potsaid; Vijaysekhar Jayaraman; Alex E. Cable; Martin F. Kraus; Joachim M. Hornegger; Jay S. Duker; David Huang; James G. Fujimoto View Presentation 382. Three-dimensional biometry and alignment in eyes implanted with Accommodative IOLs as a function of accommodative demand Susana Marcos; Sergio Ortiz; Pablo Perez-Merino; Miriam Velasco; Mengchan Sun; Judith Birkenfeld; Sonia Duran; Ignacio Jimenez-Alfaro View Presentation 383. Synchronized Real Time Imaging of Ocular Anterior Segment Biometry and Ciliary Muscle during Accommodation Aizhu Tao; Yilei Shao; Meixiao Shen; Hong Jiang; Jianguang Zhong; Dexi Zhu; Jianhua Wang View Presentation 384. Depth-of-focus of the accommodating eye Norberto Lopez-Gil; Paula Bernal-Molina; Richard Legras; Teresa Ferrer-Blasco; Robert Montés-Micó View Presentation 385. Anatomical and accommodative changes in patients undergoing cataract surgery with presbyopia accommodative lens placement Diego Chavez View Presentation 386. Accommodative Movements of the Lens/Capsule in Relation to the Vitreous Face and Aging Mary Ann Croft; Gregg A. Heatley; T Michael Nork; Jared P. McDonald; Alex Katz; Julie Kiland; Paul L. Kaufman View Presentation 387. Accommodative-Disaccommodative IOL with Zonular Capture Haptics Paul M. Beer; Paul L. Kaufman; Mary Ann Croft; Gregg A. Heatley; Jared P. McDonald; Alex Katz View Presentation 121. Ocular Fibrosis: Myofibroblast to Therapeutics - Minisymposium Moderator(s): Colm O'Brien (Mater Misericordiae Univ Hospital) and James Jester (University of California, Irvine) 10:30 AM - 12:15 PM; TCC 303 AM View Session Details View Session Details 388. Fibrosis – Keeping an Eye on the Myofibroblast Boris Hinz View Presentation 389. Fibrosis in Glaucoma: Role in Pathologenesis and Surgical Failure Colm J. O'Brien View Presentation 390. Prevention of Keratocyte-Myofibroblast Conversion by Targeting the MatrixCytokine System Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 22 sur 222 11:20 AM - 11:35 AM 11:35 AM - 11:50 AM Shizuya Saika View Presentation 391. Fibrosis in the lens: Regulation of TGFß-induced lens Epithelial to Mesenchymal Transition (EMT) leading to cataract. Frank J. Lovicu View Presentation 392. Regulation of Retinal and Subretinal Fibrosis David R. Hinton View Presentation 122. Innovations in Ocular Imaging Moderator(s): Joel Schuman (UPMC Eye Center/Univ of Pittsburgh) and David Huang (Casey Eye Institute) 10:30 AM - 12:15 PM; TCC 304 10:30 AM - 10:45 AM 10:45 AM - 11:00 AM 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 393. Ultrawide-field choroidal thickness and structure map created with MHz-OCT Thomas Klein; Wolfgang Draxinger; Wolfgang Wieser; Aljoscha S. Neubauer; Lukas Reznicek; Anselm Kampik; Robert Huber View Presentation 394. Simultaneous birefringence and flow imaging with Multifunctional Jones matrix optical coherence tomography Myeong Jin Ju; Young-Joo Hong; Shuichi Makita; Masahiro Miura; Shuo Tang; Yoshiaki Yasuno View Presentation 395. In-vivo Depth-resolved Estimation of Tissue Properties: OCT-derived Attenuation Coefficient Images Koenraad A. Vermeer; Josine van der Schoot; Hans G. Lemij; Johannes F. de Boer View Presentation 396. Imaging the mouse retina in vivo using Adaptive Optics - Fourier Domain Optical Coherence Tomography Yifan Jian; John S. Werner; Kevin Wong; Edward N. Pugh; Marinko V. Sarunic; Robert J. Zawadzki View Presentation 397. Real-time eye motion correction in phase-resolved OCT angiography with tracking SLO Boy Braaf; Kari V. Vienola; Christy K. Sheehy; Qiang Yang; Koenraad A. Vermeer; Pavan Tiruveedhula; David W. Arathorn; Austin Roorda; Johannes F. de Boer View Presentation 398. Rapid, automated measurements of single cell blood velocity in the living eye Jesse B. Schallek; Christina Schwarz; David R. Williams View Presentation 399. Parafoveal retinal vascular response to pattern stimulation assessed with OCT angiography Eric Wei; Yali Jia; Ou Tan; Benjamin Potsaid; Jonathan J. Liu; WooJhon Choi; James G. Fujimoto; David Huang View Presentation 123. ipRGCs and Circadian Rhythms Moderator(s): Russell Van Gelder (University of Washington) and Douglas McMahon (Vanderbilt University) 10:30 AM - 12:15 PM; TCC 305 10:30 AM - 10:30 AM 10:30 AM - 10:45 AM 10:45 AM - 11:00 AM 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM View Session Details Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary ALternates: Rupp, Z.Zhang, both with scores = 2; Ross-Cisneros? Include in Itinerary 400. Intrinsically Photosensitive Retinal Ganglion Cells (ipRGCs) Depend on the Retinal Pigment Epithelium (RPE) to Regenerate Melanopsin Kwoon Y. Wong View Presentation 401. Assessing Relative Rod, Cone and Melanopsin Contributions to Pupil Flicker Responses Pablo A. Barrionuevo; Nathaniel Nicandro; J Jason McAnany; Andrew J. Zele; Paul D. Gamlin; Dingcai Cao View Presentation 402. ipRGCs regulate the development of the circadian pacemaker and vision Kylie Chew; Jordan M. Renna; David S. McNeill; Shih-Kuo Chen; Haiqing Zhao; David M. Berson; Samer Hattar View Presentation 403. The photoentrainment of circadian clocks in the mammalian retina Ethan Buhr; Russell N. Van Gelder View Presentation 404. Role of Circadian Clock-Induced Enhancement of GABAA Receptor-Mediated Feedback to Cones at Night Stuart C. Mangel; Hee Joo Choi; Masaaki Ishii; Yu Cao; Adewunmi Adelaja; Jiexin Cao; Christophe Ribelayga View Presentation 405. Circadian Clock Control of Rod Photoreceptor Electrical Coupling in the Mouse Retina Nange Jin; Christophe Ribelayga View Presentation 406. Retinal function: Assessing seasonal lighting environment on physiology Chad R. Jackson; Megan E. Capozzi; Douglas McMahon View Presentation Include in Itinerary 124. Neuroprotection; Clinical Drug Studies Moderator(s): Rebecca Sappington (Vanderbilt Univ Medical Center) and Nicholas Marsh-Armstrong (Johns Hopkins Univ Sch of Med) 10:30 AM - 12:15 PM; Exhibit / Poster Hall 10:30 AM - 12:15 PM View Session Details Include in Itinerary View Session Details 407 - A0138. Olfactomedin Domain-containing Proteins, Olfm1 and Olfm2, Interact with AMPA Receptors in the Retina Afia Sultana; Naoki Nakaya; Lijin Dong; Mones S. Abu-Asab; Stanislav I. Tomarev View Presentation 408 - A0139. Antioxidant treatment responses on the neuroinflammatory outcomes of ocular hypertension in rats Gulgun Tezel; Xiangjun Yang View Presentation 409 - A0140. Up-regulation of autophagy in the glaucomatous human retina Xiangjun Yang; Jian Cai; David W. Powell; Markus H. Kuehn; Gulgun Tezel View Presentation 410 - A0141. Effect of hypoxia treatment by CoCl2 on expression of glutamate/aspartate transporters (GLAST) and unfolded protein reaction (UPR) related factors in retinal Müller cells Dan Hu; Li-Juan Sun View Presentation 411 - A0142. The Neuroprotective Effects of Coenzyme Q10 on Retinal Ganglion Cells and Its Reversal of Apoptosis Miles R. Parnell; Joana M. Galvao; Eduardo M. Normando; Shereen Nizari; Farzana Rahman; M Francesca Cordeiro View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 23 sur 222 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 412 - A0143. Mechanisms of Neuroprotection by Latanoprost for Retinal Ganglion Cells under Hypoxia Mari Katsura; Reiko Yamagishi; Makoto Aihara View Presentation 413 - A0144. Investigating Retinal Toxicity of the Potentially Neuroprotective Substance Tempol Sebastian Mueller; Rebecca Dollinger; Sebastian Thaler; Johanna Hofmann; Martin S. Spitzer; Karl U. Bartz-Schmidt; Peter Szurman; Kai Januschowski View Presentation 414 - A0145. Ganglion cell neuroprotection by angiotensin II blockers identified by drug screening in retinal explants Andrew J. White; Janosch Heller; Keith R. Martin View Presentation 415 - A0146. NFkB signaling in retinal glia mediates progressive neural degeneration and vision decline in glaucoma Caroline Lupien; Philip J. Horner; David J. Calkins View Presentation 416 - A0147. RGC Neuroprotection by Manipulating ER Stress Signaling Molecules Liu Yang; Feisi Liang; Mira Amin; Yaping Qian; Toby Ferguson; Yang Hu View Presentation 417 - A0148. A peptide derived from Prominin-1 enhances axon regeneration of retinal ganglion cells in an optic nerve injury model Zai-Long Chi; Amy E. Birsner; Avner Adini; Robert J. D'Amato View Presentation 418 - A0149. In-vitro Evaluation of the Neuroprotective Effects of Forskolin on Retinal Ganglion Cells ABUBAKAR HABIB; Gibran F. Butt; Ben Davis; Joana M. Galvao; Shereen Nizari; Eduardo M. Normando; Mark Tilley; Farzana Rahman; Li Guo; M Francesca Cordeiro View Presentation 419 - A0150. Neuroprotective effect of VCP inhibitors on mice models of glaucoma Hanako O. Ikeda; Noriko Nakano; Yuki Muraoka; Masanori Hangai; Akira Kakizuka; Nagahisa Yoshimura View Presentation 420 - A0151. Activation of Retinal Astrogliosis Compromises Ganglion Cell Survival Izzy Livne-Bar; Adrian Nahirny; Jeremy M. Sivak View Presentation 421 - A0152. Complement and Glial Activity in the Retinocollicular Pathway of Mice in a Novel Model of Glaucoma Sean Silverman; Colleen M. McDowell; Byung-Jin Kim; Robert J. Wordinger; Abbot F. Clark View Presentation 422 - A0153. Differential activation of p38 and c-jun N-terminal kinase in the visual pathway following optic nerve crush Yang Liu; Zhang Zhang; Robert J. Wordinger; Richard T. Libby; Iok-Hou Pang; Abbot F. Clark View Presentation 423 - A0154. Coenzyme Q10 ameliorates oxidative stress and preserves mitochondrial transcription factor A in ischemic retinal injury Dongwook Lee; Keun-Young Kim; Won-Kyu Ju View Presentation 424 - A0155. Effect of coenzyme Q10 on oxidative stress and mitochondrial DNA alteration in a mouse model of glaucoma Myoung Sup Sim; Dongwook Lee; Keun-Young Kim; Robert N. Weinreb; Won-Kyu Ju View Presentation 425 - A0156. Change of the expression of synapses at the retina after ocular hypertension Hae-Young L. Park; Jie Hyun Kim; Chankee Park View Presentation 426 - A0157. Intraocular pressure and cGMP aqueous humor levels in spontaneous ocular hypertensive rabbits and following transient IOP changes ennio ongini; Elena Bastia; Francesco Impagnatiello View Presentation 427 - A0158. Inhibition of Innate Immune Response Alters Detoxification Capacity of ABCB1 Transporters in Trabecular Meshwork Cells Algis Grybauskas; Kevin Skuran; Paulius Kuprys; Beatrice Yue; Paul A. Knepper View Presentation 428 - A0159. Essential Role of Brain Derived Neurotrophic Factor in the Preservation of Retinal Ganglion Cell Function Vivek Kumar Gupta; Jonathan C. Li; Yuyi You; Maarten van den Buuse; Stuart Graham View Presentation 429 - A0160. Effects of tafluprost on endothelin–1–induced retinal injury in the rat Atsushi Nagata; Katsumi Oomachi; Tomomi Higashide; Satoshi Shirae; Masatsugu Nakamura; Atsushi Shimazaki; Naruhiro Ishida; Kazuhisa Sugiyama View Presentation 430 - A0161. Celastrol Protects Retinal Ganglion Cells from Optic Nerve Crush but not from Glaucomatous Damage Haksu Kyung; Vlad Bekerman; Jacky Man Kwong Kwong; Joseph Caprioli; Natik Piri View Presentation 431 - A0162. Role Of Neuritin 1 in Response to Optic Nerve Crush Tasneem M. Putliwala; Yang Liu; Robert J. Wordinger; Abbot F. Clark View Presentation 432 - A0163. Protective effect of GFAP antibody on RGC5 cells via actin cytoskeleton pathways Corina Wilding; Katharina Bell; Sebastian Funke; Sabine Beck; Norbert Pfeiffer; Franz H. Grus View Presentation 433 - A0164. Adenosine A3 receptor agonist inhibits retinal ganglion cell apoptosis in vivo Joana M. Galvao; Li Guo; Ana Raquel Santiago; Antonio F. Ambrosio; M Francesca Cordeiro View Presentation 434 - A0165. Reversal of Apoptosis in Retinal Ganglion Cells Farzana Rahman; Shereen Nizari; Joana M. Galvao; Miles R. Parnell; ABUBAKAR HABIB; Eduardo M. Normando; M Francesca Cordeiro View Presentation 435 - A0166. Expression of CCL5 Signaling Machinery in Healthy and Glaucomatous Retina D'Anne S. Duncan; Sean J. Lee; Rebecca M. Sappington View Presentation 436 - A0167. Glaucomatous retinopathy and neuropathy following laser-induced ocular hypertension in African green monkeys Wenzheng Hu; Robin J. Goody; Michael J. Struharik; Steve D. Whittaker; Steve t. Henry; Rohn Brookes; Matthew S. Lawrence View Presentation 437 - A0168. TRPV1-/- Accelerates Neurodegeneration From Microbead-Induced Ocular Hypertension Nicholas J. Ward; Karen W. Ho; Wendi S. Lambert; David J. Calkins View Presentation 438 - A0169. Interactions Between Dendritic Cells, Microglia, and Retinal Ganglion Cells Following Injury to the Optic Nerve Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 24 sur 222 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM Dale S. Gregerson; Neal D. Heuss; Mark J. Pierson; Kim Ramil C. Montaniel; Scott W. McPherson; Thien N. Sam View Presentation 439 - A0170. Caloric Restriction Protects Against Loss of RGC Differentiation Following Optic Nerve Injury James D. Lindsey; Karen Xuandao Duong-Polk; Dustin Hammond; Christopher K. Leung; Robert N. Weinreb View Presentation 440 - A0171. Safety and tolerability following single dose of ONO-9054 in healthy volunteers Cheryl L. Rowe-Rendleman; Takafumi Ouchi; Douglas T. Ross; Andrew T. Wood View Presentation 441 - A0172. Single dose pharmacokinetics of ONO-9054 in healthy volunteers Takafumi Ouchi; Cheryl L. Rowe-Rendleman; Douglas T. Ross; Fumitaka Suto; Andrew T. Wood View Presentation 442 - A0173. POSTURAL INTRAOCULAR PRESSURE CHANGES IN TRABECULECTOMIZED AND MEDICALLY-TREATED GLAUCOMA EYES Akira Sawada; Tetsuya Yamamoto View Presentation 443 - A0174. Association between glaucoma, glaucoma therapies, and erectile dysfunction Nawaaz Nathoo; Mahyar Etminan; Frederick S. Mikelberg View Presentation 444 - A0175. Intravitreal Bevacizumab or Ranibizumab for Rubeosis Iridis – 3 years follow up Joao J. Nassaralla; João J. Nassaralla; Belquiz A. Nassaralla View Presentation 445 - A0176. The Use of Complementary and Alternative Medicine for Glaucoma in South Korea Jonghoon Shin; Hyun-kyung Cho; Mingui Kong; Changwon Kee View Presentation 446 - A0177. Preservative-free tafluprost 0.0015%/timolol 0.5% fixed dose combination: a 6-month double-masked, randomized multicenter P-III comparison to concomitant use of the individual preservative-free components in patients with glaucoma or ocular hypertension Gabor Hollo; Anton B. Hommer; Alfonso Anton; Auli M. Ropo View Presentation 447 - A0178. The investigation of influence of glaucoma surgery for instillation adherence Tomoko Yoshikawa; Itaru Kimura; Satoshi Watanabe; Ayumi Usui; Akira Murakami; Nobuyuki Ebihara View Presentation 448 - A0179. Effects of prostaglandin analogues with various preservatives on the ocular surface of the rabbit Hyun Joo Lee; Roo Min Jun; Kyu-Ryong Choi View Presentation 449 - A0180. Six-Month Results From a Phase 3 Randomized Trial of FixedCombination Brinzolamide 1%/Brimonidine 0.2% Quang H. Nguyen; Jess T. Whitson; Tony Realini; Stephen M. Goode; Matthew G. McMenemy View Presentation 450 - A0181. Short and long-term evaluation of the effects of subconjunctival infiltration of mitomycin C (MMC) in rabbits, comparing dose and time Luiza R. Vilela; Ana Flávia Oliveira; Fabio N. Kanadani; Maria Luiza Reis; Tereza M. Kanadani; Rubens Vilela; Priscila R. Vilela; Raquel Vilela View Presentation 451 - A0182. Treatment of refractory glaucoma using UC procedure with High Intensity Focused Ultrasound.(HIFU) . Prospective series Jean-Francois J. Rouland; Florent Aptel View Presentation 452 - A0183. Analysis of Intraocular Pressure-Lowering Effects of Preservative-Free Tafluprost and Timolol in Patients with Open-Angle Glaucoma and Ocular Hypertension in a Phase-III, Randomized, Double-Masked Study John W. Grunden; Robert J. Lupinacci; Rohit Varma View Presentation 453 - A0184. Efficacy, safety, and improved tolerability of preservative-free timolol 0.1% gel formulation compared with prior a BAK-preserved therapy Paolo Frezzotti; Michele Figus; Carlo Cagini; Ilaria Motolese; Chiara Posarelli; Anna Bartolini; Simone Alex Bagaglia; Alessandra De Carolis; Eduardo Motolese View Presentation 454 - A0185. Preservative-free tafluprost in the treatment of naïve patients with glaucoma and ocular hypertension Ines M. Lanzl; Thomas Hamacher; Friedemann Kimmich View Presentation 455 - A0186. Topical Glaucoma Therapy Cost Alejandra Hernández-Oteyza; Gabriel Lazcano-Gomez; María J. Iriarte; Jesus JimenezRoman View Presentation 456 - A0187. Efficacy, safety, and efficiency of self instillation of eye drops by glaucoma patients Meghan Park; Michael B. Choi; Marguerite Huff; Catherine Clark; Clara Choo; Mark Maroongroge; Jie Peng; Alfred W. Rademaker; Angelo P. Tanna View Presentation 457 - A0188. Medication persistency of newly medicated Japanese glaucoma patients Short title: Medication persistency of newly glaucoma patients Toshie Furuya; Kenji Kashiwagi View Presentation 458 - A0189. A Randomized, Phase I Dose-Escalation Study to Evaluate Tolerability, Safety and Pharmacokinetics (PK) of Trabodenoson in Healthy Older-Adult Volunteers Alan M. Laties; Randall Stoltz; Chaim Brickman; Vernon Humbert; N. Slomowitz; William McVicar; Rudolf Baumgartner View Presentation 459 - A0190. Inter-rater reproducibility in the assessment of video recordings of eye drop instillation by glaucoma patients Marguerite Huff; Meghan Park; Michael B. Choi; Daniel Sarezky; Catherine Clark; Clara Choo; Jie Peng; Alfred W. Rademaker; Angelo P. Tanna View Presentation 460 - A0191. Latanoprostene Bunod 0.024% Significantly Reduces and Maintains Mean Diurnal Intra-Ocular Pressure (IOP) Compared to Latanoprost 0.005% in Subjects with Open Angle Glaucoma or Ocular Hypertension L Jay Katz; Paul L. Kaufman; Tuyen Ong; Baldo Scassellati-Sforzolini; Jason L. Vittitow View Presentation 125. Lens Development and Aging Moderator(s): Salil Lachke (University of Delaware) and Robbert De Iongh (University of Melbourne) 10:30 AM - 12:15 PM; Exhibit / Poster Hall 10:30 AM - 12:15 PM View Session Details 461 - B0001. Ephrin-A5 and EphA2 regulate lens development and cataract formation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 25 sur 222 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM through distinct mechanisms Catherine Cheng; Xiaohua Gong View Presentation 462 - B0002. Dephosphorylation of CREB Regulates Its Functions on Lens Differentiation Xiao-Hui Hu; Wenfeng Hu; Weike Ji; Mi Deng; Lili Gong; Zachary Woodward; Wenbin Liu; Shaojun Liu; David W. Li View Presentation 463 - B0003. Prox1 may regulate growth factor receptor expression during lens fiber differentiation Dylan S. Audette; Melinda K. Duncan View Presentation 464 - B0004. The dosage effect of pax6 in lens epithelial cells induction from iPSCs Jin Yang; Yi Lu View Presentation 465 - B0005. Knockdown of Collagen 11A1 decreases zebrafish lens and optic cup diameter during early development Marc Yonkers; Julia T. Oxford View Presentation 466 - B0006. Fibrillin-2 is a component of the mouse zonule Lauren Beene; Lauren Wang; Robert P. Mecham; Dieter Reinhardt; Elias I. Traboulsi; Suneel S. Apte View Presentation 467 - B0007. AP-2α and AP-2β are Required for Normal Lens Development Christine L. Kerr; Trevor Williams; Judith A. West-Mays View Presentation 468 - B0008. CDK1 is required for both lens epithelial cell proliferation and fiber cell denucleation Michael L. Robinson; Blake R. Chaffee; Fu Shang; Mitch Eddy; Brad D. Wagner; Tracy M. Clement; Allen Taylor View Presentation 469 - B0009. Roles of de novo DNA methylation in zebrafish lens development Pawat Seritrakul; Jeffrey M. Gross View Presentation 470 - B0010. Searching for stem-like cells in the lens epithelium Yuki Sugiyama; Elizabeth Shelley; Frank J. Lovicu; John W. McAvoy View Presentation 471 - B0011. A new experimental model for studies of capsule bound epithelial cells in the rat Martin Kronschlager; Nooshin TalebiZadeh; Zhaohua Yu; Per G. Söderberg View Presentation 472 - B0012. Mapping and quantifying lens epithelial cell proliferation in a rodent model of lens regeneration Weiju Wu; Noemi Lois; Shane A. Richards; Christopher Saunter; Rosie Fordyce; Roy Quinlan View Presentation 473 - B0013. Using EdU in whole pig lenses to establish anterior epithelial cell division rates Emily Davis; Kelli Theisen; George McArdle; Rebecca K. Zoltoski View Presentation 474 - B0014. Protein Phosphatase-1 and –2A Dephosphorylate p53 at Ser-20 to Control Growth-Factor-Induced Differentiation and Stress-Induced Apoptosis of Lens Epithelial Cells Weike Ji; Wenfeng Hu; Xiao-Hui Hu; Fang-Yuan Liu; Xiangcheng Tang; Kaili Wu; Mi Deng; Lili Gong; Yizhi Liu; David W. Li View Presentation 475 - B0015. Down regulation of CHIP disturbs the balance of protein quality control systems in lens epithelial cells Wanjun Zhang; Liangping Liu; Zhenzhen Liu; Mingxing Wu; Yizhi Liu View Presentation 476 - B0016. Loss of Dlg-1 in the Mouse Lens Impairs FGFR Signaling Sungkyoung Lee; Anne E. Griep View Presentation 477 - B0017. The Function of the E3 Ligase, MDM2 Is Subjected to Dephosphorylation Regulation by Protein Serine/Threonine Phosphatase-1 and -2A Wenfeng Hu; Xiao-Hui Hu; Weike Ji; Mi Deng; Zachary Woodward; David W. Li View Presentation 478 - B0018. The temporal and spatial range and spectrum of autophagy and mitophagy genes expressed during lens cell differentiation and development Daniel Chauss; Subhasree Basu; Lisa A. Brennan; A S. Menko; Marc Kantorow View Presentation 479 - B0019. Downregulation of Syndecan-4 by RNA Interference Inhibits Adhesion and bFGF-induced Proliferation of Lens Epithelial Cells Yi Zhu; Chuan Chen; Ying Lin; Yizhi Liu; Mingxing Wu View Presentation 480 - B0020. A Role for the Fat/Dachsous System in Lens Development John W. McAvoy; Yuki Sugiyama; Christopher G. Harris; Lucy J. Dawes; Elizabeth Shelley; Caroline Badouel; Helen McNeill; Frank J. Lovicu View Presentation 481 - B0021. Methylation of CpG Island in Aging Lens Epithelial Cells And During Oxidative Stress Affects Sp1 Binding And Activity in LEDGF Promoter Dhirendra P. Singh; Bhavana Chhunchha; Biju Bhargavan; Eri Kubo; Nigar Fatma View Presentation 482 - B0022. Molecular chaperone αA-crystallin interacts with the Inhibitor of Caspaseactivated DNase (ICAD)/ Caspase-activated DNase (CAD) complex in the developing lens Caitlin Logan; A S. Menko View Presentation 483 - B0023. Caspase-3 expression in rat lens epithelium Nooshin TalebiZadeh; Zhaohua Yu; Martin Kronschlager; Per G. Soderberg View Presentation 484 - B0024. Quantitative Analysis of Lens Membrane Protein Modifications with Fiber Cell Morphology Jamie L. Wenke; Kevin L. Schey View Presentation 485 - B0025. N- or C- Terminal Cleavage of Mature Fiber Cell Aquaporin 0 Does Not Impede the Water Channel and Cell-to-Cell Adhesion Functions Kulandaiappan Varadaraj; Sindhu Kumari View Presentation 486 - B0026. Effect of UV and blue light on cytoskeletal and membrane proteins in porcine lens epithelial cells in culture Alfred R. Wegener; Heike Laser-Junga; Frank G. Holz View Presentation 126. Contact Lens I Moderator(s): Lyndon Jones (University of Waterloo) 10:30 AM - 12:15 PM; Exhibit / Poster Hall 10:30 AM - 12:15 PM Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary View Session Details Include All in Itinerary 487 - B0124. Evaluation of Surface Water Characteristics of Novel Daily Disposable Include in Itinerary 28/03/2013 Abstract Central Page 26 sur 222 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM Contact Lenses Using Refractive Index Shifts after Wear Jeffery Schafer; Robert B. Steffen View Presentation 488 - B0125. Effect of Protein Adsorption on Dewetting and Corneal cell adhesion on Contact Lenses Saad Bhamla; Claire M. Elkins; David Bergsman; Gerald G. Fuller View Presentation 489 - B0126. Secretory Phospholipase A2 Type IIA Levels across the Wear Cycle: Response to Lens Age or Indication of CL Intolerance Walter L. Nash; Alan Landers; Manal M. Gabriel; Jennifer D. Lane; Michael S. Foster View Presentation 490 - B0127. Characterization of contact lenses through oxygen permeability, equilibrium water content, and silicone content Scott Curtin; Michelle Seitz; Meng Ouyang; Katarina Tomic; Meredith Wiseman; Hanny Vanwersch View Presentation 491 - B0128. Effect of lens care system on silicone hydrogel contact lens wettability Cecile A. Maissa; Michel Guillon; Stephanie Wong; Anna Lane; Trisha Patel; Renee J. Garofalo View Presentation 492 - B0129. Effect of care solutions on contact lens in-vivo wettability at insertion and end of day Alan Tomlinson; Raied Fagehi; Velitchko Manahilov View Presentation 493 - B0130. Laboratory Model for Wear of Contact Lenses and Effects on Lens Lubricity of Surface Gel Layers W G. Sawyer; Juan M. Uruena; Thomas E. Angelini; Alison C. Dunn; John Pruitt View Presentation 494 - B0131. Assessment of the relationship between contact lens coefficient of friction and subject lens comfort Jami R. Kern; Joseph M. Rappon; Erich Bauman; Ben Vaughn View Presentation 495 - B0132. Surface Elastic Modulus of a Unique Hydrogel Material Measured with Colloidal Probe AFM Yuchen Huo; Alexander Rudy; Scott S. Perry; John Pruitt View Presentation 496 - B0133. Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) causes corneal epithelial thinning without altering overall corneal thickness or hysteresis Peter G. Coombs; Ryan M. St Clair; Yvonne Wang; Michelle N. Lee; Christopher E. Starr; Jessica Ciralsky; Kimberly C. Sippel; Priyanka Sood; Mark Rosenblatt; Ana G. Alzaga Fernandez View Presentation 497 - B0134. Selenium covalently incorporated into the polymer of contact lens case material inhibits bacterial biofilm formation Ted W. Reid; Phat L. Tran; Thomas Mosley; Courtney Jarvis; Daniel Webster; Robert E. Hanes; Abdul Hamood View Presentation 498 - B0135. Effect of Oxidation on Binding of Fatty Acids to PureVision and Acuvue Contact Lenses Thomas J. Millar; Burkhardt S. Schuett View Presentation 499 - B0136. In-Vivo Wettability of Contact Lenses Worn in a Low Humidity Environmental Exposure Chamber (LH-EEC) Show Comparable Changes to Traditional Field Trials Fiona Soong; Jalaiah P. Varikooty; Nancy J. Keir; Lyndon W. Jones; Piyush Patel View Presentation 500 - B0137. Viscoelasticity and mesh-size at the surface of hydrogels characterized with microrheology Thomas E. Angelini; Ryan M. Nixon; Alison C. Dunn; Juan M. Uruena; John Pruitt; W G. Sawyer View Presentation 501 - B0138. In vitro Uptake and Release of Natamycin Dex-b-PLA Nanoparticles from Silicone Hydrogel Contact Lens Materials Chau-Minh Phan; Lakshman N. Subbaraman; Lyndon W. Jones; Shengyan Liu; Frank Gu View Presentation 502 - B0139. Effects of Silicone Hydrogel Contact Lenses Applied Immediately After Sub-Bowman’s Keratomileusis Xingwu Zhong; Shaohui Gao View Presentation 503 - B0140. High levels of sIgA and exudated serum albumin in tears of contact lens related Dry Eye patients three months after discontinuation of lens use Piera Versura; Alberto Bavelloni; Chiara Coslovi; William Blalock; Marco Grillini; giuseppe giannaccare; Emilio C. Campos View Presentation 504 - B0141. Comparative Cleaning Ability of Rigid Gas Permeable Lens Care Systems Kimberly A. Millard; Suzanne F. Groemminger View Presentation 505 - B0142. Corneal Uptake of Oxygen In Vivo During Soft Contact Lens Wear Percy Lazon De La Jara; Sho C. Takatori; Klaus Ehrmann; Arthur Ho; Brien A. Holden; Clayton J. Radke View Presentation 506 - B0143. Adhesion of Stenotrophomonas maltophilia, Delftia acidovorans and Achromobacter xylosoxidans to contact lenses Ajay Kumar Vijay; Mark D. Willcox View Presentation 507 - B0144. Antimicrobial Activity of Melimine or Cathelicidin Bound to Contact Lenses Debarun Dutta; Mark D. Willcox View Presentation 508 - B0145. Establishing a standard method for evaluating efficacy against Acanthamoeba Monica Crary; Rhonda Walters; John Bartell; Manal M. Gabriel; Jagath Kadurugamuwa; Bradley J. Catalone View Presentation 509 - B0146. Risk Factors for Contact Lens Related Microbial Keratitis in Singapore Chris Lim; Nicole A. Carnt; Mohamed Farook; Janice Lam; Jodhbir S. Mehta; Donald T. Tan; Fiona Stapleton View Presentation 510 - B0147. The Antimicrobial Efficacy of Human Tear Proteins after Repeated Exposure to Contact Lens Solutions Bianca L. Price; Philip B. Morgan; Carole Maldonado-Codina; Curtis B. Dobson View Presentation 511 - B0148. Traveler's Contact Lens Associated Keratitis (TCLAK): Establishing Preventive and Treatment Guidelines To Close A Gap in Ophthalmic Care Fallon Ukpe; Stephanie Youlios; Bela Parekh; Jai G. Parekh View Presentation 512 - B0149. Lipid Adherence to Model Contact Lens Materials Holly I. Lorentz; Giuliano Guidi; Lyndon W. Jones; Heather Sheardown View Presentation 513 - B0150. Quorum Sensing Molecules in the Preferential Selection of Pseudomonas Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 27 sur 222 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM aeruginosa from Contaminated Contact lens Cases Darlene Miller; Katyayini Aribindi; Galina Dvoriantchikova; Dmitry V. Ivanov; Sanjoy K. Bhattacharya; Jorge Maestre; Eduardo C. Alfonso View Presentation 514 - B0151. Selenium Contact Lens Hydrogel Polymer: Inhibition of Bacterial Biofilm Formation Phat L. Tran; Abdul Hamood; Daniel Webster; Courtney Jarvis; Robert E. Hanes; Ted W. Reid View Presentation 515 - B0152. Contact Lens Disinfecting Solution vs. Blister Pack: a Subjective Evaluation Scott Schatz; Balamurali Vasudevan; Sara N. Gaib; Kimbal Cooper View Presentation 516 - B0153. Antimicrobial Efficacy of New Investigational Multipurpose Disinfecting Solution and Comparison to Commercially Available Multipurpose Disinfecting Solutions Marina Milenkovic; Nancy Brady; Anthony Lam View Presentation 517 - B0154. Efficacy of multi-purpose solutions in removing cholesterol deposits from silicone hydrogel contact lenses Hendrik Walther; Lakshman N. Subbaraman; Lyndon W. Jones View Presentation 518 - B0155. Antimicrobial Efficacy of Multipurpose Disinfecting Solutions against Clinical Isolates after Prolonged Storage Anthony Lam; Nancy Brady; Marina Milenkovic View Presentation 519 - B0156. Disinfection Efficacy of Rigid Gas Permeable Lens Care Systems Suzanne F. Groemminger; Denise Callahan View Presentation 520 - B0157. Effect of Contact Lenses and Lens Cases on Disinfection Efficacy of Four Multipurpose Disinfection Solutions Manal M. Gabriel; Cynthia McAnally; John Bartell; Rhonda Walters; Jebree Spencer; Linda Clark; Bradley J. Catalone View Presentation 521 - B0158. The Evaluation of the Biocidal Efficacy of Multi-Purpose Solutions Against Mixed Cultures of Pseudomonas aeruginosa with a Variety of Individual Fungal Organisms Jessica M. Burger; Deborah McGrath; Brien C. David View Presentation 522 - B0159. Evaluation of Biocidal Efficacy of Multipurpose Solutions Against Gram Negative Organisms in a Lens Case Brien C. David; Denise Callahan; Julie Bair; Susan E. Norton View Presentation 523 - B0160. Efficacy Of Contact Lens Solutions Against Achromobacter xylosoxidans Biofilms Using Confocal Microscopy David J. McCanna; Jaclyn M. Chang; Lakshman N. Subbaraman; Lyndon W. Jones View Presentation 127. Corneal Epithelium and Imaging I Moderator(s): Matthew Petroll (Univ Texas Southwestern Med Ctr) 10:30 AM - 12:15 PM; Exhibit / Poster Hall 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM View Session Details 524 - B0161. Body mass index, peripheral corneal thickness and anterior chamber depth in young European adults - A pilot study Sven Jonuscheit; Michael J. Doughty; Raul Martin; Ana del Rio San Cristóbal; Lisa J. Mackintosh; David MacTaggart; Michael Hiscock View Presentation 525 - B0162. Objective Estimation for Uncertainty of Restoring Corneal Topography Surface Anatoly Fabrikant View Presentation 526 - B0163. Corneal nerve plexus condition in type 2 Diabetes Mellitus patients assessed by Confocal Microscopy Juan Antonio De la Campa; Oscar Baca; Alejandro Babayan; Regina Velasco; Cristina Pacheco-Del-Valle View Presentation 527 - B0164. Non-invasive objective metrics of Bulbar Hyperemia for Clinical Trials Endpoints Neha Gadaria-Rathod; Kyu-In Lee; Benyamin Y. Ebrahim; Penny A. Asbell View Presentation 528 - B0165. Clinical Validation of the Cassini Color LED Corneal Topography (CLCT) in post penetrating keratoplasty (PKP) Ronald Ensing; Fleur de Lange; Harry de Vries; Michel Zaal; Victor A. Sicam View Presentation 529 - B0166. Topographically Guided Corneal Cross-Linking David B. Usher; Radha Pertaub; Marc D. Friedman; Ronald F. Scharf; David Muller View Presentation 530 - B0167. Corneal nerve morphology: a non-invasive surrogate of nerve fibre damage and repair in chemotherapy-associated peripheral neuropathy Bernardo F. Sanchez Dalmau; Marisol Lopez Moreno; Ruben Torres; Santiago OrtizPerez; Dolores Vela; Elena Fraga; Pablo Villoslada View Presentation 531 - B0168. Laser In Vivo Confocal Microscopy Demonstrates a Lower Density of Peripheral Corneal Nerve Fibers Compared to the Central Cornea in Normal Subjects Jae Young You; Bernardo M. Cavalcanti; Susan Cheng; Monique L. Trinidad; Douglas Critser; Amy Watts; Charles D. Leahy; Christine W. Sindt; Pedram Hamrah View Presentation 532 - B0169. Riboflavin Dosimetry in the Cornea using a KXL-II and the Scheimpflug Principle Marc D. Friedman; David B. Usher; Radha Pertaub; David Muller View Presentation 533 - B0170. The clinical utility of the Eye Surface Profiler D Robert Iskander View Presentation 534 - B0171. Subclinical Keratoconus Detection Based On Pentacam Scheimpflug Tomography Indices Pablo R. Ruisenor Vazquez; Marianella Delrivo; Fernando Fuentes Bonthoux; Tomás Pfortner; Pablo Chiaradia; Jeremias G. Galletti View Presentation 535 - B0172. Change of corneal irregular astigmatism after pterygium excision surgery Keiichiro Minami; Ayami Masuda; Yosai Mori; Ryohei Nejima; Kazunori Miyata View Presentation 536 - B0173. Measuring Corneal Epithelial Thickness Change after LASIK with Optical Coherence Tomography Maolong Tang; Yan Li; David Huang View Presentation 537 - B0174. Normal Variants of Human Limbus Detected by In Vivo Laser Scanning Confocal Microscopy Elfren R. Baclagon; Siamak Zarei-Ghanavati; Sophie X. Deng View Presentation 538 - B0175. Imaging of epithelial downgrowth following penetrating keratoplasty by confocal microscopy and high-resolution optical coherence tomography Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 28 sur 222 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM Vivian Lien; Michael Chen; Dennis E. Cortes; Jennifer Li; Mark J. Mannis View Presentation 539 - B0176. Role of glutathione peroxidase 4 in maintaining homeostasis of corneal epithelial cells Osamu Sakai; Takashi Ueta; Yasuo Yanagi; Shiro Amano View Presentation 540 - B0177. A New Method for the Efficient and Less-Stress Dissociation of Corneal Epithelial Cells Katsuhiko Shinomiya; Satoshi Kawasaki; Keita Aoi; Koji Kitazawa; Shigeru Kinoshita View Presentation 541 - B0178. Characterization of cultured corneal epithelial cells on the genipincrosslinking Descemet membrane Lung-Kun Yeh; Shih-Chun Huang View Presentation 542 - B0179. The Role of Nrf2-Mediated Defense System in Corneal Epithelial Wound Healing Ryuhei Hayashi; Noriko Himori; Keiko Taguchi; Yuki Ishikawa; Kohji Uesugi; Motokazu Tsujikawa; Toru Nakazawa; Masayuki Yamamoto; Kohji Nishida View Presentation 543 - B0180. Increased fragility and acceleration of migration of corneal epithelial cells in an epiplakin deficiency Masahide Kokado; Yuka Okada; Kazushi Ishikawa; Hiromitsu Shimada; Sakuhei Fujiwara; Masayasu Miyajima; Shizuya Saika View Presentation 544 - B0181. Transfer of mucosal epithelial cells and extracellular matrix by a gelatin matrix technique in vitro Allen Ho; Li-Fang Wang View Presentation 545 - B0182. Medical management of limbal stem cell deficiency with anti-inflammatory therapy and tear film optimization Bryan Kim; Pejman Bakhtiari; Kamran Riaz; Clara C. Chan; Jeffrey Welder; Surendra Basti; Ali R. Djalilian View Presentation 546 - B0183. Neuroprotectin D1 Stimulates the Expression and Secretion of Nerve Growth Factor in Corneal Epithelial Cells Azucena H. Kakazu; Nicolas G. Bazan; Haydee E. Bazan View Presentation 547 - B0184. Multicentric study validation of a new molecular method for Limbal Stem Cell Deficiency diagnosis based on MUC5AC transcript detection in corneal epithelium by reverse dot-blot strip Tatiana M. Suarez-Cortes; Iker Garcia; Jaime Etxebarria ; Jesus Merayo-Lloves; Josep Torras; Ana Boto-de-los-Bueis; David Diaz-Valle; Rosalia Mendez; Xabier Landaluce; Arantxa Acera View Presentation 548 - B0185. Optimized culturing conditions for limbal epithelial cells cultivated on semisynthetic collagen matrices Corinna Petsch; Ursula Schlotzer-Schrehardt; Markus Frey; Johannes Menzel-Severing; Friedrich E. Kruse; Bjoern O. Bachmann View Presentation 549 - B0186. CD45+F4/80+ immune cells are rapidly recruited to the wound edge after corneal debridement wounds Gauri Tadvalkar; Sonali Ghosh; Ahdeah Pajoohesh-Ganji; Janice L. Walker; A S. Menko; Mary Ann Stepp View Presentation 550 - B0187. Basement Membrane Removal Reduces Inflammation in the Mouse Cornea and Enhances Wound Healing Sonali Pal-Ghosh; Ahdeah Pajoohesh-Ganji; Gauri Tadvalkar; Daniel R. Saban; Mary Ann Stepp View Presentation 551 - B0188. Schirmer Testing and Corneal Surface Findings in Chronic Graft-VersusHost Disease Kathleen M. Williamson; Evan Allan; Michelle P. Lin; Michael C. Wu View Presentation 552 - B0189. Boric Acid-based Multipurpose Contact Lens Care Solutions (MPSs) Cytotoxicity Effect on Human Corneal Epithelial Cells Kissaou T. Tchedre; Masaki Imayasu; Yuichi Hori; H D. Cavanagh View Presentation 553 - B0190. The Effect of Amniotic Membrane De-epithelialization Method on its Biological Properties and Ability to Promote Limbal Epithelial Cell Culture Gary Hin-Fai Yam; Ting Zhang; Andri K Riau; Roger W. Beuerman; Donald T. Tan; Jodhbir S. Mehta View Presentation 554 - B0191. Knockdown of MUC16 Alters Tight Junctions of Corneal Epithelial Cells Resulting in Decreased Transepithelial Resistance Ilene K. Gipson; Sandra J. Spurr-Michaud; Ann S. Tisdale View Presentation 555 - B0192. Rapamycin helps to maintain colony forming efficiency in corneal epithelial cells Farnoud YOUSEFIMILANI; Behrad Y. Milani; Hossein M. Sagha; Ali R. Djalilian View Presentation 556 - B0193. Average Corneal Epithelial Thickness Pattern of Normal, Post-LASIK, PostPRK, KCN, Contact Lens Wearer, and Dry Eyes Using RTVue FD-OCT System Yao Nie; Qienyuan Zhou; Kelly A. Soules; Ben K. Jang View Presentation 557 - B0194. Bone Marrow derived Mesenchymal Stem Cells for Reconstructing the Limbal Niche Ali R. Djalilian; Behrad Y. Milani; Hossein M. Sagha; Peiman Hematti View Presentation 558 - B0195. Decreased Phosphorylation at the Serine-2 Residue of the RNA Polymerase II in Corneal Epithelial Stem Cells Satoshi Kawasaki; Katsuhiko Shinomiya; Keita Aoi; Shigeru Kinoshita View Presentation 559 - B0196. Effect of Specular Focal Distance on Endothelial Cell Counting Accuracy Jackie Hai; Vivian Xue View Presentation 560 - B0197. Evaluation of Terrien Marginal Degeneration Using Anterior Segment Optical Coherence Tomography Xiaoqiang Liu; Fang Wang View Presentation 561 - B0198. Human graft cornea imaging with full-field optical coherence tomography Wajdene Ghouali; Kate Grieve; Otman Sandali ; Elena Basli; Julien Bullet; Laurent Laroche; Vincent Borderie View Presentation 562 - B0199. High-Resolution Anterior Segment Optical Coherence Tomography and in vivo Confocal Microscopy in the Evaluation of Corneal Dystrophies Dennis E. Cortes; Jennifer Li; Michael Chen; Raju Poddar; Robert J. Zawadzki; John S. Werner; Mark J. Mannis View Presentation 563 - B0200. Analysis Of Early Postoperative Morphologic Features Of Clear Corneal Incisions Created With The Femtosecond Cataract Laser Using Anterior Segment Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 29 sur 222 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM Optical Coherence Tomography: Comparison Of Intended Versus Achieved Wound Parameters Surendra Basti; Dilraj S. Grewal View Presentation 564 - B0201. Epithelial Basement Membrane Dystrophy: A Study with in vivo Confocal Microscopy and High-Resolution Anterior Segment Optical Coherence Tomography Peter Wu; Dennis E. Cortes; Jennifer Li; Michael Chen; Mark J. Mannis View Presentation 566 - B0203. Study Of Ocular Surface impairment in children presenting ongoing dry eye with MGD with Meibomian Gland Analysis Dominique Bremond-Gignac; Solange Milazzo View Presentation 567 - B0204. Gender differences in ocular biometric data yoona jang; Hiroshi Uozato; Takushi Kawamorita; Yuko Shibata View Presentation 128. Spatial Vision, Visual Psychophysics and Aging I Moderator(s): Jason Marsack (University of Houston) 10:30 AM - 12:15 PM; Exhibit / Poster Hall 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 568 - C0179. The effect of posterior vitreous detachment or vitreous opacities (floaters) on straylight measurements Miguel Castilla; Marc D. de Smet View Presentation 569 - C0180. Visual findings in children with Autistic Spectrum Disorder Pamela M. Anketell; Kathryn J. Saunders; Stephen M. Gallagher; Clare Bailey; JulieAnne Little View Presentation 570 - C0181. Videogame Experience Enhances Temporal Visual Attention in Adult Amblyopia: The Attentional Blink in Amblyopia Charlie V. Ngo; Truyet Tran; Calvin Nguyen; Dennis M. Levi; Roger W. Li View Presentation 571 - C0182. Suppression of the Implicit Surface Susan Kelly; Yi Pang View Presentation 572 - C0183. Postural adaptation to large optic flow fields Guillaume L. Giraudet; Clementine Faron; Jocelyn Faubert View Presentation 573 - C0184. Measurement of stimulus contrast and fading under natural and manipulated motion trajectories Nicole M. Putnam; Pavan Tiruveedhula; Austin Roorda View Presentation 574 - C0185. Dynamic stimulus presentation facilitates peripheral resolution acuity Peter R. Lewis; Victoria Holm; Karthikeyan Baskaran; Jorgen Gustafsson View Presentation 575 - C0186. Distance Visual Acuity Screening of Preschoolers with Hyperopia Marjean T. Kulp; Gui-Shuang Ying; Jiayan Huang; Maureen G. Maguire; Graham E. Quinn; Elise Ciner; Deborah A. Orel-Bixler; Lynn A. Cyert; Bruce Moore View Presentation 576 - C0187. Comparison of foveal and perifoveal acuity in myopia Stephanie X. Shao; Nancy J. Coletta View Presentation 577 - C0188. iPad-Based Quick CSF Implementation to Assess Effects of Dioptric Blur on Contrast Sensitivity Michael Dorr; Luis A. Lesmes; Zhong-Lin Lu; Peter Bex View Presentation 578 - C0189. Repeatability of Visual Acuity with a Chart Having Lines of Equivalent Legibility Lawrence R. Stark; Scot A. Class View Presentation 579 - C0190. The Effect of Exposure Duration on Visual Acuity for Letter Optotypes Depends On How Visual Acuity is Defined J Jason McAnany; Philip R. Nolan; Aimee Beluch View Presentation 580 - C0191. Assessing the Quality of Functional Vision through AdSpecs. Nadine Solaka; Hilary Gaiser; Joshua Silver; Bruce Moore View Presentation 581 - C0192. Neural substrates of perceptual integration during bistable object perception Anastasia V. Flevaris; Antigona Martinez; Steven Hillyard View Presentation 582 - C0193. Digital precise remote near visual acuity evaluation using mobile devices Oren Yehezkel; Anna Sterkin; Maria Lev; Uri Polat View Presentation 583 - C0194. The Handy Eye CheckTM: A Mobile Medical Application for Testing Vision in Children Amy K. Hutchinson; Keri Stalun; Michael J. Lynn; T R. Candy View Presentation 584 - C0195. Influence of glare light on contrast sensitivity through absorptive lenses Hiroshi Uozato; Masatsugu Kanazawa View Presentation 585 - C0196. Novel method to objectively evaluate visual comfort during sunglass use George A. Zikos; Samantha Slotnick; Rocco Robilotto; Arkady Selenow; Steven R. Ali View Presentation 586 - C0197. Influence of Thermal Lensing on Human Visual Function Erica L. Towle; Michelle T. Aaron; Leon N. McLin; Benjamin A. Rockwell View Presentation 129. ROP Moderator(s): Antonio Capone (Associated Retinal Consultants) and Shunji Kusaka (Sakai Hosp Kinki Univ Faculty of Med) 10:30 AM - 12:15 PM; Exhibit / Poster Hall 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM View Session Details View Session Details 587 - D0109. Quantitative Analysis of Vitreous Humor Reveals Distinct Protein Profiles in Patients with Retinopathy of Prematurity sonika rathi; Subhabrata Chakrabarti; Ganeswara R. Musada; Subhadra Jalali; Ramesh Kekunnaya; Inderjeet Kaur View Presentation 588 - D0110. Vascular Stabilization with Adipose Stromal Cells in Retinopathy of Prematurity Breedge Callaghan; Chandrika Abburi; Pamela I. Rogers; Brian C. Samuels; Keith L. March; Gangaraju Rajashekhar View Presentation 589 - D0111. Gap Junctions and Retinal Angiogenesis Jessica M. Ackert; Tamas Atlasz View Presentation 590 - D0112. Cornea, crystalline lens and whole ocular refractive power in premature infants with retinopathy of prematurity at one year of age Takako Tachikawa; Ritsuko Ueno; Daisuke Yuzurihara; Tetsuko Mita; Osamu Katsumi; Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 30 sur 222 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM Toru Noda; Kazuhiko Ohnuma View Presentation 591 - D0113. Effects of Lower Dosage of Intravitreal Bevacizumab in Retinopathy of Prematurity Yuta Saito; Isamu Ito; Toshihiko Ueda; Michiko Matsubara; Eiichi Nishimura; Haruo Takahashi View Presentation 592 - D0114. Vitreoretinal interfase changes in the fibrovascular demarcation line after intravitreal bevacizumab for type 1 retinopathy of prematurity Rafael Romero Vera; Alay Banker; Rosa E. Martinez; Samantha Salinas Longoria; Guillermo Salcedo-Villanueva; Hugo E. Sepulveda-Vazquez; Maria A. MartinezCastellanos View Presentation 593 - D0115. Refraction Changes After The Use of Bevacizumab in The Treatment Of Patients With Prethreshold Retinopathy Of Prematurity Yi hsing Chen; Nan-Kai Wang; Yen-Po Chen; An-Ning Chao; Kuan-Jen Chen; Yih-Shiou Hwang; Chi-Chun Lai; Wei-Chi Wu View Presentation 594 - D0116. Screening for Retinopathy of Prematurity in China Yu Xu; Qin Zhang; Qi Zhang; Xiaohong Zhou; Yonghong Zhang; Jing Li; Peiquan Zhao View Presentation 595 - D0117. The Incidence of Retinopathy of Prematurity in Armenia Albert Hovhannisyan; Cassandra Fink; Anna S. Brown; Susan Ostmo; Robison V. Chan; Tadevos Hovhannisyan; Ruzanna Harutyunyan; Inga Sargsyan ; Michael F. Chiang; Thomas C. Lee View Presentation 596 - D0118. Treatment Of Type I Pre-Threshold and Threshold Retinopathy Of Prematurity in Northern Colombia- Efficacy of Laser Alone Paul J. Rychwalski; Jenny V. Lobo Lopez; Sarah K. Jordan; Carlos A. Abdala View Presentation 597 - D0119. Computer-based image analysis for ROP: development of a quantitative index based on vascular tortuosity Grant Aaker; Daniel Lattin; Esra Ataer-Cansizoglu; Katie M. Keck; Deniz Erdogmus; Jayashree Kalpathy-Cramer; Michael F. Chiang View Presentation 598 - D0120. An Analysis of the Retinal Vascular Development in a Mouse Model of Bronchopulmonary Dysplasia Stuart D. Rollins; Jonathan Chou; Joann M. Taylor; Gina Kim; Kathryn N. Farrow; Amani A. Fawzi View Presentation 599 - D0121. Armenian ROP EyeCare Project: Agreement Between Ophthalmoscopic Diagnosis by Newly Trained Local Ophthalmologists vs. Remote Image-Based Diagnosis by Experts Anna S. Brown; Susan Ostmo; Cassandra Fink; Roger Ohanesian; Nune Yeghiazaryan; Levon Grigoryan; R.V. Paul Chan; Michael F. Chiang; Thomas C. Lee View Presentation 600 - D0122. BREASTFEEDING AS A PROTECTIVE FACTOR FOR RETINOPATHY OF PREMATURITY: A CASE-CONTROL STUDY John Hernandez; Carlos Felipe Castaño; Liliana M. Zuluaga; Gloria I. Salazar; Eddy P. Monsalve; Jorge Donado View Presentation 601 - D0123. Candidate Gene Study of Retinopathy of Prematurity in Extremely Low Birthweight Infants from the Neonatal Research Network M Elizabeth Hartnett; Grier Page; Michael Cotten; Jeff Murray; Margaret M. DeAngelis View Presentation 602 - D0124. Luminance-response functions for light-adapted electroretinograms (ERGs) in preterm infants at risk of retinopathy of prematurity (ROP) Daphne L. McCulloch; Helen Mactier; Lesley Farrell; Gen Hanazono; Ruth Hamilton View Presentation 603 - D0125. Wnt Signaling Mutations can Compromise Peripheral Retinal Vascular Development and Confuse the Diagnosis in Prematurely Born Infants Michael T. Trese; Joshua Robinson; Antonio Capone; Kimberly A. Drenser View Presentation 604 - D0126. Iridocorneal angle characteristics of infants with retinopathy of prematurity (ROP) compared to full-term infants using spectral domain optical coherence tomography Linda A. Cernichiaro-Espinosa; Veronica E. Giordano; Magdalena García-Huerta; Samantha Salinas Longoria; Rafael Romero Vera; Gerardo Garcia-Aguirre; Guillermo Salcedo-Villanueva; Hugo Quiroz-Mercado; Maria A. Martinez-Castellanos; Linda A. Cernichiaro-Espinosa View Presentation 605 - D0127. Role of the Krebs Cycle metabolite α-ketoglutarate and its receptor, GPR99, in retinal angiogenesis Francois Duhamel; Karine Zaniolo; Houda Tahiri; Sylvain Chemtob View Presentation 606 - D0128. Circadian Clock Gene Regulation of Retinal Neovascularization Lili Xu; John S. Penn; Douglas McMahon View Presentation 607 - D0129. Defective Wnt-signaling is associated with progressive retinopathy in Incontinentia pigmenti (IP) Cagri G. Besirli; Joshua Robinson; Ekta Lakhani; Michael T. Trese View Presentation 608 - D0130. Quantifying vascular tortuosity in retinopathy of prematurity: impact of segmentation method and vascular length Daniel Lattin; Grant Aaker; Esra Ataer-Cansizoglu; Dongseok Choi; Katie M. Keck; Rony Gelman; Jayashree Kalpathy-Cramer; Deniz Erdogmus; Michael F. Chiang View Presentation 609 - D0131. Progesssion of Myopia and Anisometropia in Individual Children with Regressed Retinopathy of Prematurity Jingyun Wang; Xiaowei Ren; Li Shen; Susan E. Yanni; Joel Leffler; Eileen E. Birch View Presentation 610 - D0132. Primary Rescue Therapy In The Treatment Of Threshold Retinopathy Of Prematurity Carlos A. Abdala; Jenny V. Lobo Lopez; Sarah K. Jordan; Paul J. Rychwalski View Presentation 611 - D0133. Angiographic Features of FEVR versus ROP Audina M. Berrocal; Vishak J. John View Presentation 612 - D0134. New onset macular edema after laser photocoagulation for retinopathy of prematurity Dordi Austeng; Ramiro S. Maldonado; Sharon F. Freedman; David Wallace; Cynthia A. Toth View Presentation 613 - D0135. NADPH oxidase, NOX1, is a key source of oxidative stress in retinopathy and neovascularization Jennifer L. Wilkinson-Berka; Devy Deliyanti; Indrajeetsinh Rana; Alex Agrotis; Roksana Armani; Kirstin Wingler; Rhian Touyz; Mark E. Cooper; Karin Jandeleit-Dahm; Harald H. Schmidt View Presentation 614 - D0136. Risk Factors for Treatment-Requiring Retinopathy of Prematurity and Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 31 sur 222 10:30 AM - 12:15 PM Withdrawn 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM Implications for Screening Guidelines Sarah Jordan; Jenny V. Lobo Lopez; Paul J. Rychwalski; Carlos A. Abdala View Presentation 615 - D0137. Adiponectin mediates protective effect of omega-3 long-chain polyunsaturated fatty acid in retinopathy of prematurity Zhongjie Fu; Chatarina Lofqvist; Aimee Juan; Zhenghao Cui; Dorothy T. Pei; Christian G. Hurst; Lucy Evans; Jing Chen; Ann Hellström; Lois E. Smith View Presentation 616 - D0138. Expression of eNOS and VEGF in Normoxia Mediated Vasculopathy in Rat Retinopathy of Prematurity Model Alireza Hosseini; Frank A. Lattanzio; Nazita Yousefieh; Ryan R. Wade; Jorge L. Jacot View Presentation 617 - D0139. Validation and Characterization of Murine Oxygen-induced Retinopathy of Prematurity Model Yubin Qiu; Amber Woolfenden; Wei Zheng; Karen Anderson; Melinda Hubbard; John Demirs; Joseph Loureiro; Joy Ghosh; Stephen H. Poor; Bruce D. Jaffee View Presentation 618 - D0140. Induction Of The VEGF-related Proteins Prokineticin 1 and 2 In The Ischemic Retina Frances Fan; Folami Lamoke; Sean Shaw; Babak Baban; Manuela Bartoli View Presentation 619 - D0141. Foveal Fine Structure in Retinopathy of Prematurity (ROP) Subjects: an Adaptive Optics Spectral Domain Optical Coherence Tomographic Study Emily A. Swanson; James D. Akula; Tara L. Favazza; Daniel X. Hammer; R. D. Ferguson; Anne Moskowitz; Ronald M. Hansen; Anne B. Fulton View Presentation 620 - D0142. Evaluation of a portable, non-contact digital fundus camera (Pictor) in premature infants Sasapin G. Prakalapakorn; David Wallace; Sharon F. Freedman View Presentation 621 - D0143. Knockdown of Mueller cell specific VEGF reduces retinal neovascularization in a rat model of retinopathy of prematurity (ROP) Manabu McCloskey; Yanchao Jiang; Haibo Wang; zhihong yang; Jeremy Strange; Tal Kafri; John G. Flannery; M Elizabeth Hartnett View Presentation 622 - D0144. Macular Morphology Before and After Intravitreal Bevacizumab in Patients with Retinopathy of Prematurity: A Spectral Domain Ocular Coherence Tomography Comparative Case Series Martin Guzman-Sanchez; Veronica E. Giordano; Samantha Salinas Longoria; Rafael Romero Vera; Guillermo Salcedo-Villanueva; Virgilio Morales-Canton; Hugo QuirozMercado; Maria A. Martinez-Castellanos View Presentation 623 - D0145. Antagonizing IL-1β effectively prevents inner and outer retinal degenerative changes associated with retinopathy of prematurity Tianwei (Ellen) Zhou; Jose Carlos Rivera; Isabelle Lahaie; Zhuo Shao; Anna Polosa; Allison L. Dorfman; Pierre Lachapelle; Sylvain Chemtob View Presentation 624 - D0146. Handheld Spectral Domain Optical Coherence Tomography as a Tool to Assess Retinopathy of Prematurity Zone and Stage in Premature Infants Ronald W. Milam; Jan N. Ulrich; Michelle T. Cabrera View Presentation 625 - D0147. Correlation of clinically undetected macular features by spectral domain OCT and angiography in early stages of retinopathy of prematurity Cynthia Villalobos-Ojeda; Veronica E. Giordano; Samantha Salinas Longoria; Rafael Romero Vera; Guillermo Salcedo-Villanueva; Gerardo Garcia-Aguirre; Virgilio MoralesCanton; Hugo Quiroz-Mercado; Maria A. Martinez-Castellanos View Presentation 626 - D0148. Macular findings in preterm Non-Retinopathy Of Prematurity infants using Spectral Domain Optical Coherence Tomography Samantha Salinas Longoria; Veronica E. Giordano; Rafael Romero Vera; Gerardo Garcia-Aguirre; Guillermo Salcedo-Villanueva; Virgilio Morales-Canton; Hugo QuirozMercado; Maria A. Martinez-Castellanos View Presentation 627 - D0149. Net Weight Gain from Birth to Time of First Retinopathy of Prematurity (ROP) Examination as Sole Inclusion Criteria for Screening Examinations for ROP Jennifer L. Hsu; Christopher Shelvock; Stefan Sillau; Robert Enzenauer; Rebecca S. Braverman View Presentation 628 - D0150. Analysis of the Tomographic Macular Morphology in Premature Newborn Patients with Retinopathy of Prematurity Rodrigo Lechuga Perezanta; Veronica E. Giordano; Samantha Salinas Longoria; Rafael Romero Vera; Gerardo Garcia-Aguirre; Guillermo Salcedo-Villanueva; Virgilio MoralesCanton; Hugo Quiroz-Mercado; Maria A. Martinez-Castellanos View Presentation 629 - D0151. Variations in Retinal Nuclear Areas in a Neonatal Mouse Model of Retinopathy of Prematurity by Histopathology Olachi J. Mezu-Ndubuisi; Norman P. Blair; Amy Lin; Justin Wanek; Narsa M. Reddy; Usha Raj; Sekhar P. Reddy; Mahnaz Shahidi View Presentation 630 - D0152. Influence of the difference of Breastfeeding volume on a Rat Model of Oxygen-induced Retinopathy Michiko Matsubara; Yuta Saito; Takako Nakanishi-Ueda; Toshihiko Ueda; Tadashi Hisamitsu; Haruo Takahashi View Presentation 631 - D0153. Anterior Chamber Angle Evaluation with Spectral-Domain Optical Coherence Tomography in preterm patients with and without retinopathy of prematurity Andrea Portilla Demichelis; Magdalena García-Huerta; Veronica E. Giordano; Samantha Salinas Longoria; Rafael Romero Vera; Armando Castillejos-Chevez; Guillermo SalcedoVillanueva; Virgilio Morales-Canton; Hugo Quiroz-Mercado; Maria A. MartinezCastellanos View Presentation 632 - D0154. Review of retinopathy of prematurity in Asahikawa Medical University Hospital, Japan Ichiro Tanano; Eiichi Sato; Hiroyuki Hirokawa; Akitoshi Yoshida View Presentation 633 - D0155. Choroidal Thickness in Patients with a History of Retinopathy of Prematurity Wei-Chi Wu; Chia-Pang Shih; Nan-Kai Wang; Rey-In Lin; Yen-Po Chen; An-Ning Chao; Kuan-Jen Chen; Yih-Shiou Hwang; Chi-Chun Lai; Shawn Tsai View Presentation 634 - D0156. FA findings in regressed mild rop Domenico Lepore; Pierdavide Perrini; Fernando Molle; Lorenzo Orazi; Antonio Baldascino; Rachele DeSantis View Presentation 635 - D0157. Sequential vascular changes followed by angiography in spontaneously regressed retinopathy of prematurity in infants born greater than 32 weeks gestation and birthweight greater than 1250g with high oxygen dependance ARCELIA DEL ROCIO VILLASEÑOR GARCIA; Hugo E. Sepulveda-Vazquez; Guillermo Salcedo-Villanueva; Samantha Salinas Longoria; Rafael Romero Vera; Gerardo GarciaAguirre; Hugo Quiroz-Mercado; Maria A. Martinez-Castellanos View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 32 sur 222 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 636 - D0158. Next Generation Sequencing Analysis of Gene and Pathway Regulation in the Rat Model of Retinopathy of Prematurity Tara L. Favazza; Rachel M. Griffith; Hu Li; Nan Zhang; Ronald M. Hansen; Anne B. Fulton; James D. Akula View Presentation 637 - D0159. OCT findings in mild ROP Rachele DeSantis; Antonio Trabacca; Domenico Lepore; Fernando Molle; Pierdavide Perrini; Lorenzo Orazi View Presentation 638 - D0160. Wide field fluorescein angiography vs indirect ophthalmoscopy in the screening of retinopathy of prematurity (ROP); Does understanding better the vascular pathology became essential in diagnosis and management of ROP? Fernando Cisneros-Luna; Guillermo Salcedo-Villanueva; Samantha Salinas Longoria; Rafael Romero Vera; Fernando Schoonewolff; Hugo Quiroz-Mercado; Maria A. MartinezCastellanos View Presentation 130. Retinitis Pigmentosa I Moderator(s): Yoshihiro Hotta (Hamamatsu Univ Sch of Med) and David Birch (Retina Fndn of the Southwest) 10:30 AM - 12:15 PM; Exhibit / Poster Hall 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM View Session Details 639 - D0161. Photoreceptors in whirler mice show defective transducin translocation and are susceptible to light-induced degeneration Dominic E. Cosgrove; Mei Tian; Wei-Min Wang; Marisa L. Zallocchi; You-Wei Peng View Presentation 640 - D0162. Long-term follow-up of patients with retinitis pigmentosa (RP) receiving sustained-release CNTF through intraocular encapsulated cell technology implants David G. Birch; Kirsten G. Locke; Travis Porco; Martin Klein; Austin Roorda; Weng Tao; Jacque L. Duncan View Presentation 641 - D0163. Light-Induced Rod Death in RHO P23H Swine Triggers Microglial Invasion, TNF-α Release and Rapid Blue Cone Loss Sang-Joon Lee; Wei Wang; Henry J. Kaplan; Douglas C. Dean View Presentation 642 - D0164. Correlation of retinal sensitivity with the area of normal auto-fluorescence in choroideremia patients Markus Groppe; Charles Cottriall; Susan M. Downes; Robert E. MacLaren View Presentation 643 - D0165. Intravitreal Autologous Bone-Marrow Stem Cells in Retinitis Pigmentosa Patients: One-Year Results Rafael S. Arcieri; Katharina Messias; Vinicius M. Castro; Rubens C. Siqueira; Rodrigo Jorge; Andre Messias View Presentation 644 - D0166. Evaluation of Inner Retinal Layers in Patients with Retinitis Pigmentosa Using Optical Coherence Tomography Kenzo Hokazono; Rithambara Ramachandran; Lisa Zhou; Kirsten G. Locke; David G. Birch; Donald C. Hood View Presentation 645 - D0167. Transmission Electron Microscopic Study of P23H Retinopathy in a Swine Model of Retinitis Pigmentosa Patrick A. Scott; Henry J. Kaplan View Presentation 646 - D0168. Evaluation of fundus autofluorescence in retinitis pigmentosa using ultra wide-field scanning laser ophthalmoscope Yukitoshi Shimoda; Shoji Kishi View Presentation 647 - D0169. Test-Retest Variability for Semi-Automated Kinetic Perimetry and GATE Static Perimetry in Retinitis Pigmentosa Dawn Peters; Elvira N. Chegarnov; Laura Erker; Mark E. Pennesi; Richard G. Weleber View Presentation 648 - D0170. Pupillometry in Patients with Leber Congenital Amaurosis: Feasibility, Residual Retinal Cell Function, and Paradoxical Response Radwan Ajlan; Leah M. Wood; Jamie Koenekoop; Sorathnoorani Siddiqui; Irma Lopez; Vafa Keser; Ayesha Khan; Huanan Ren; Rui Chen; Robert K. Koenekoop View Presentation 649 - D0171. Is solute carrier protein (SC1) a novel gene for autosomal recessive retinitis pigmentosa? Alice Y. Zhang; Shen Li; Huanan Ren; Irma Lopez; Sorathnoorani Siddiqui; Dror Sharon; Ayesha Khan; Paul R. Goodyer; Rui Chen; Robert K. Koenekoop View Presentation 650 - D0172. Role of ER Stress-Induced Caspase12 in Retinal Degeneration of T17M RHO mice Yogesh Bhootada; Shreyasi Choudhury; Marina S. Gorbatyuk View Presentation 651 - D0173. Phase I Trial of Subretinal Injection of a Recombinant Adeno-Associated Virus (rAAV2-VMD2-hMERTK) Gene Vector to Patients with MERTK RP Nicola G. Ghazi; Fowzan S. Alkuraya; Abdulrahman Al-Maghamsi; Fahad Al Saikhan; Emad B. Abboud View Presentation 652 - D0174. Integrated in silico and in vitro characterization of Rhodopsin mutations causing RP4 Valeria Marigo; Petra Behnen; Angelo Felline; Francesca Fanelli View Presentation 653 - D0175. Identification and Characterization of Mouse Antisense Oligonucleotides (ASOs) Directed at Rhodopsin Ali Jazayeri; Raechel Peralta; Andy Watt; Susan Freier; Gene Hung; Bea DeBrosseSerra; Shuling Guo; Sue F. Murray; Michael L. McCaleb; Brett P. Monia View Presentation 654 - D0176. Photoreceptor Vision and Structure in LCA1 caused by Mutations in GUCY2D Artur V. Cideciyan; Samuel G. Jacobson; Igor V. Peshenko; Alexander M. Sumaroka; Elena V. Olshevskaya; Alejandro J. Roman; Sam Sadigh; Elise Heon; Edwin M. Stone; Alexander M. Dizhoor View Presentation 655 - D0177. High-resolution Imaging of Retinal Structure in Retinitis Pigmentosa and Usher Syndrome Christopher Langlo; Derek Denney; Robert F. Cooper; Dennis P. Han; David V. Weinberg; Judy E. Kim; Alfredo Dubra; Kimberly E. Stepien; Thomas B. Connor; Joseph Carroll View Presentation 656 - D0178. Identification of a novel mutation in the PRCD gene causing autosomal recessive retinitis pigmentosa in a Turkish family Ditta Zobor; Johanna Pach; Florian Gekeler; Susanne Kohl View Presentation 657 - D0179. Comparison of spectral domain optical coherence tomography images in cone rod dystrophy and rod cone dystrophy Akio Oishi; Ken Ogino; Yukiko Makiyama; Masafumi Kurimoto; Maho Oishi; Norimoto Gotoh; Nagahisa Yoshimura View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 33 sur 222 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 658 - D0180. Relation between Sustained Chronic Inflammatory Reaction and Oxidative Damage in an Animal Model of Retinitis Pigmentosa Noriko Yoshida; Yasuhiro Ikeda; Shoji Notomi; Keijiro Ishikawa; Yusuke Murakami; Toshio Hisatomi; Hiroshi Enaida; Tatsuro Ishibashi View Presentation 659 - D0181. Screening of PRPH2/RDS in patients with autosomal dominant retinitis pigmentosa reveals novel disease-causing mutations and 8.6% prevalence in French population Gael Manes; Claire-Marie Dhaenens; Werner L. Vos; Isabelle S. Audo; Xavier Zanlonghi; Sylvie Odent; Helene Dollfus; Beatrice Bocquet; Isabelle Meunier; Christian P. Hamel View Presentation 660 - D0182. Correlation of morphology and function in a mouse model of X-linked retinitis pigmentosa Dorothee Roell; Jutta U. Schlegel; Christoph Friedburg; Birgit Lorenz; Knut Stieger View Presentation 661 - D0183. Video Head Impulse Test in Retinitis Pigmentosa patients Carmela Carnevale; Nicola Iozzo; Mario Gagliardi; Giuseppe Magliulo; Roberto Grenga View Presentation 662 - D0184. Reproducibility of Goldmann Visual Field digitization by minimally trained operators Michael P. Barry; Liancheng Yang; Rebecca Marcus; Gislin Dagnelie View Presentation 663 - D0185. A new mouse model for Fam161a-associated retinal ciliopathy Marcus Karlstetter; Albert Caramoy; Alexander Aslanidis; Eva Scheiffert; Nadine Bremicker; Herbert Jägle; Thomas Langmann View Presentation 664 - D0186. Modulation of Cellular signaling Pathways in P23H Rhodopsin Rat Retina Vishal M. Shinde; Olga Sizova; Marina S. Gorbatyuk View Presentation 665 - D0187. Changes to the Transition Zone with Progression of X-Linked Retinitis Pigmentosa Rebecca B. Bausell; Rithambara Ramachandran; Cindy X. Cai; Kirsten G. Locke; David G. Birch; Donald C. Hood View Presentation 666 - D0188. A Longitudinal Study of Stargardt Disease: Quantitative Assessment of Fundus Autofluorescence, Progression and Genotype Correlations Kaoru Fujinami; Noemi Lois; Rajarshi Mukhopadhyay; Vikki A. McBain; Kazushige Tsunoda; Kazuo Tsubota; Fred W. Fitzke; Anthony T. Moore; Andrew R. Webster; Michel Michaelides View Presentation 667 - D0189. Blocking mGluR1 receptors but not GABAA receptors increases light responsiveness of retinal ganglion cells in a rat model of retinitis pigmentosa Ralph J. Jensen View Presentation 668 - D0190. The Prevalence Of Residual Visual Field Islands In Retinitis Pigmentosa Mary Varsamidis; Chi D. Luu; Peter N. Dimitrov; Robyn H. Guymer; Lauren N. Ayton View Presentation 669 - D0191. Follow-up Of 36 Years In Autosomal Dominant Gyrate-Atrophy Like Choroidal Dystrophy Ulrich Kellner; Simone Kellner; Silke Weinitz; Gazaleh Farmand; Heidi Stoehr; Bernhard H. Weber View Presentation 670 - D0192. A Comparison of Methods For Tracking Progression in Patients with XLinked Retinitis Pigmentosa Using Frequency Domain OCT Rithambara Ramachandran; Lisa Zhou; Kirsten G. Locke; David G. Birch; Donald C. Hood View Presentation 671 - D0193. Therapeutic Effect of Prolonged Treatment with Topical Dorzolamide for Cystoid Macular Edema in Patients with Retinitis Pigmentosa Yasuhiro Ikeda; Noriko Yoshida; Shoji Notomi; Yusuke Murakami; Toshio Hisatomi; Hiroshi Enaida; Tatsuro Ishibashi View Presentation 672 - D0194. Caspase-7 Ablation Protects the T17M Rhodopsin Mice from Severe Retinal Degeneration through Reprograming of the UPR and inhibition of TRAF2-JNK Apoptosis Shreyasi Choudhury; Yogesh Bhootada; Oleg Gorbatyuk; Marina S. Gorbatyuk View Presentation 673 - D0195. Changes in Visual Function during 2-year Follow-up after UF-021 Therapy for Retinitis Pigmentosa Yosuke Nakamura; Akira Hagiwara; Ken Kumagai; Shuichi Yamamoto View Presentation 674 - D0196. Exome sequencing as a new approach for genetic screening in inherited retinal degeneration Zi-Bing Jin; Xiu-Feng Huang; Dong-Jun Xing View Presentation 675 - D0197. A Novel Valosin-Containing Protein Inhibitor Suppresses Photoreceptor Degeneration in a Rabbit Model of Retinitis Pigmentosa Yuki Muraoka; Hanako O. Ikeda; Noriko Nakano; Tomoko Hasegawa; Akira Kakizuka; Nagahisa Yoshimura View Presentation 676 - D0198. GCC and RPE change analysis in Retinitis Pigmentosa (RP) using Fourier domain optical coherence tomography (FD-OCT) Chang Ki Yoon; Hyeong Gon Yu View Presentation 677 - D0199. A comprehensive screen of the USH2A gene in 185 patients with autosomal recessive retinal disease Eva Lenassi; Zubin Saihan; Zheng Li; Marko Hawlina; Anthony T. Moore; Linda M. Luxon; Karen P. Steel; Maria Bitner-Glindzicz; Andrew R. Webster View Presentation 678 - D0200. Does retinitis pigmentosa cause depression? Augustinus Laude; Tock H. Lim; Adrian Koh; Fulton Wong; Roy Tan; Leslie E. Lim View Presentation 679 - D0201. Aberrant Ganglion Cell Activity varies with Morphology in a Mouse Model of Retinitis Pigmentosa Christopher Yee; Abduqodir Toychiev; Elena Ivanova; Botir T. Sagdullaev View Presentation 680 - D0202. Syndromal Retinitis Pigmentosa Associated with a 12p13.33 Duplication Singles out a Ciliopathy Gene TULP3 as a Candidate for RP Pierre Bitoun; Andree Delahaye; Brigitte Benzacken; Eva Pipiras View Presentation 681 - D0203. 30 Year Clinical Follow-Up of Original Family With Autosomal Dominant Vitreoretinochoroidopathy (ADVIRC) Senad Osmanovic; Clement C. Chow; Norman P. Blair View Presentation 682 - D0204. Mutations in MVK cause non-syndromic autosomal recessive retinitis pigmentosa Anna M. Siemiatkowska; Monique Stoffels; Kornelia Neveling; Anna Simon; Martin van Hagen; Anneke I. Den Hollander; Frans P. Cremers; L. I. van den Born; Rob W. Collin View Presentation 683 - D0205. SD-OCT May Predict Response to QLT091001 in Patients with LCA or RP Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 34 sur 222 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM associated with RPE65 or LRAT Mutations Yuquan Wen; David G. Birch View Presentation 684 - D0206. Large Animal Model of Autosomal Recessive RP due to a CNGB1 gene mutation Simon M. Petersen-Jones; Paige A. Winkler; Joshua T. Bartoe; Patrick J. Venta; Kari Ekenstedt View Presentation 685 - D0207. Effect of Pupil Dilatation on Normative Data for Full-Field Stimulus Threshold (FST) for White, Blue and Red Stimulus Colors André D. Ruppert; Sarah B. Godoi; Nivaldo Sena; Katharina Messias; Rafael S. Arcieri; Andre Messias View Presentation 686 - D0208. A spontaneously occurring mouse Rp1 missense mutation causing outer segment shortening and progressive retinal degeneration Delu Song; Steven F. Grieco; Allan Hunter; Yafeng Li; Lan Ying Shi; Qin Liu; Eric A. Pierce; John Lambris; Patsy M. Nishina; Joshua L. Dunaief View Presentation 687 - D0209. Scotopic retinal function in patients with Usher syndrome Vittoria De Rosa; Stefano Valente; Mariella Salomone; Erika Rigoni; Paolo Trabucco; Enzo M. Vingolo View Presentation 688 - D0210. Fundus autofluorescence and OCT thickness evaluation in P23H rats Isabel Pinilla Lozano; Francisco J. Segura Calvo; Lorena Fuentes-Broto; Jose M. Tamarit; Eduardo Romanos; Laura Fernandez-Sanchez; Carmen López-de La Fuente; Ana I. Sanchez-Cano; Francisco J. Ascaso; Nicolas Cuenca View Presentation 689 - D0211. Multiple Rings or Arcs of Hyperautoflourescence in Different Retinitis Pigmentosa Phenotypes Ana Fakin; Martina Jarc-Vidmar; Maja Šuštar; Jelka Brecelj; Branka Stirn Kranjc; Marko Hawlina View Presentation 690 - D0212. A novel heterozygote E2331* mutation in PRPF8 gene causes a severe phenotype of Retinitis Pigmentosa with early loss of visual acuity Olga Passarin; Francis L. Munier; Viet H. Tran; Daniel F. Schorderet; Veronika Vaclavik View Presentation 131. Retina/RPE Biochemistry: Proteins and Metabolism Moderator(s): James Hurley (University of Washington) and S Patricia Becerra (National Eye Institute) 10:30 AM - 12:15 PM; Exhibit / Poster Hall 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM View Session Details 691 - D0248. Retinal metabolic pathways: a comparative study with cerebellum, hippocampus and olfactory bulb Jianhai Du; Whitney M. Cleghorn; Guy C. Chan; Jonathan Linton; Martin Sadilek; Viren . Govindaraju; James B. Hurley View Presentation 692 - D0249. Unique expression and regulation of glycolytic enzyme PKM2 in Photoreceptor cells and the role of enzymatic activity modulating metabolism of the retina Ken Lindsay; Jonathon Linton; James B. Hurley View Presentation 693 - D0250. Metabolic pathways of photoreceptors in light and dark Whitney M. Cleghorn; Jianhai Du; Martin Sadilek; Viren . Govindaraju; James B. Hurley View Presentation 694 - D0251. Nitric Oxide Leads to Cytoskeletal Reorganization and Apoptosis in Retinal Pigment Epithelium O'Donnell Sylvester; Srinivas R. Sripathi; Weilue He; Trevor Moser; Paul S. Bernstein; Folami Lamoke; Manuela Bartoli; Megan C. Frost; Wan Jin Jahng View Presentation 695 - D0252. Prohibitin Depletion Leads to RPE Apoptosis in Age-Related Macular Degeneration Wan Jin Jahng; O'Donnell Sylvester; Trevor Moser; Folami Lamoke; Paul S. Bernstein; Manuela Bartoli; Srinivas R. Sripathi View Presentation 696 - D0253. Rhodopsin ADRP Mutant Ter349Glu Causes Retinal Inflammation and Early-Onset Degeneration T J Hollingsworth; Alecia K. Gross View Presentation 697 - D0254. UNC119B, an UNC119/RG4 paralog expressed in retina and RPE Cecilia D. Gerstner; Houbin Zhang; Jeanne M. Frederick; Wolfgang Baehr View Presentation 698 - D0255. In Depth Analysis of Retinal Proteins using a Combinatory HPLC based Mass Spectrometric Platform Sebastian Funke; Dominik Wolters; Lukas Weiler; Francis K. Mwiiri; Katharina Bell; Corina Wilding; Norbert Pfeiffer; Franz H. Grus View Presentation 699 - D0256. Regulation of Synaptic and Gap Junctional Proteins in the Retina by Rhodopsin-Regulated Protein Kinase D Jesse Peterson; Amitavo Mitra; Minzhong Yu; Edward J. Dudek; Jinsong Yang; Neal S. Peachey; Janis Lem View Presentation 700 - D0257. Mapping the Receptor-binding Site on PEDF: Implications for a Neurotrophic Role of PEDF-R Jason Kenealey; Preeti Subramanian; David Hoover; S Patricia Becerra View Presentation 701 - D0258. Monitoring Kinetic Changes of Proper and Improper Rhodopsin Transport ex vivo Joshua Sammons; Alecia K. Gross View Presentation 702 - D0259. Characterisation of a novel antibody against the loop between TMD 3 and 4 of human Bestrophin1 Caroline Pasquay; Annabella Janise; Birgit Lorenz; Markus N. Preising View Presentation 703 - D0260. The presynaptic glutamate transporter in rods binds to a distinct subset of PDZ domain containing proteins Sarah Hengel; Joseph G. Laird; Will Watkins; Randy A. Hall; Sheila A. Baker View Presentation 704 - D0261. Differential Analysis of Retinal Guanylyl Cyclase GUCY2D (RetGC1) Activation and Binding with GCAP1 and RD3 Using In Vitro Activity Assay and Cellbased Binding Assay Igor V. Peshenko; Elena V. Olshevskaya; Alexander M. Dizhoor View Presentation 705 - D0262. Multiple isoforms of TRIP8b, a regulator of HCN channels, are expressed in retina Yuan Pan; Joseph G. Laird; Sheila A. Baker View Presentation 706 - D0263. VAMP7 as a Regulator of Rhodopsin Transport Carrier Fusion in Photoreceptors Bridgette Ray; Beatrice M. Tam; Orson L. Moritz; Dusanka Deretic Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 35 sur 222 View Presentation 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 707 - D0264. Arrestin inhibits AldolaseC activity J Hugh McDowell; W Clay Smith; Susan N. Bolch; Donald R. Dugger View Presentation 708 - D0265. Glutathione S-Transferase Pi Isoform (GSTP1) Expression in Murine Retina Decreases with Aging Wen-Hsiang Lee; Pratibha M. Joshi; Rong Wen View Presentation 132. Retinal and Photoreceptor Degeneration I: Cell Biology Moderator(s): Steven Fliesler (SUNY-Buffalo / VA Med Ctr-Buffalo) 10:30 AM - 12:15 PM; Exhibit / Poster Hall 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM View Session Details 709 - D0266. Microglial phagocytosis as apoptosis-independent mechanism for rod photoreceptor death in rd10 mice Lian Zhao; Robert Fariss; Wai T. Wong View Presentation 710 - D0267. Metabolomic Analysis of a Rat Model of the Smith-Lemli-Opitz Syndrome (SLOS) Christopher C. Goulah; Eduard Struys; Erwin E. Jansen; Steven J. Fliesler View Presentation 711 - D0268. Retinal Remodeling in a Rat Model of the Smith-Lemli-Opitz Syndrome Steven J. Fliesler; Christopher C. Goulah; William D. Ferrell; Robert E. Marc; Bryan W. Jones View Presentation 712 - D0269. In Vitro Toxicity of 7-Dehydrocholesterol-Derived Oxysterols Depends on Retinal Cell Type Bruce A. Pfeffer; Libin Xu; Ned A. Porter; Steven J. Fliesler View Presentation 713 - D0270. Photoreceptor Degeneration and Retinal Remodeling in P23H Transgenic Swine Doug Emery; Ilya Chernyavskiy; Henry J. Kaplan; Patrick A. Scott View Presentation 714 - D0271. Dim light rearing slows the decline in post-photoreceptor function in the Rs1-KO mouse Sten Kjellstrom; Ronald A. Bush; Yong Zeng; Paul A. Sieving View Presentation 715 - D0272. The Flexibility of the Rod Photoreceptor Outer Segment Mohammad Haeri; Aphrodite Ahmadi; Barry E. Knox View Presentation 716 - D0273. Choroideremia is a Systemic Disease with Retinal Crystals, Lymphocyte Crystals and Serum Lipid Abnormalities Naveen Mysore; Sangni Cao; Jamie Koenekoop; Huanan Ren; Vafa Keser; Irma LopezSolache; Sorathnoorani Siddiqui; Ayesha Khan; Shen Li; Robert K. Koenekoop View Presentation 717 - D0274. Network Oscillations in the Outer Retina in the Rod-Degenerated Mouse Retina Timm Schubert; Blanca Arango-Gonzalez; Eberhart Zrenner; Thomas Euler; Wadood Haq View Presentation 718 - D0275. Mechanism dissection and gene therapy of the LCA3 mouse model Rui Chen; Abuduaini Abulimiti; Huidan Xu; Hua Zhong; David L. Simons; Julian EsteveRudd; Lin Gan; Samuel M. Wu; David S. Williams; Graeme Mardon View Presentation 719 - D0276. Transcutaneous Microcurrent Electrical Stimulation (MCS) in the Therapy of Previously Untreatable Retinal Diseases Kellen Kashiwa; Michael D. Bennett; Fayssal El-Jabali; georgios papastergiou; Karl E. Waite View Presentation 720 - D0277. Rpe65 gene therapy restores precise visual responses in vitro to many retinal ganglion cells in Rpe65-/- mice Steven F. Stasheff; Frederick R. Blodi; Malini Shankar; Jeannette Bennicelli; Jean Bennett; Sajag Bhattarai; Arlene V. Drack; Stewart Thompson View Presentation 721 - D0278. TNFα spontaneously secreted in an organotypic culture of porcine neuroretina is blocked by adalimumab Ivan Fernandez-Bueno; Maria Teresa Garcia-Gutierrez; GirishKumar Srivastava; Manuel J Gayoso; Jose-Carlos Pastor View Presentation 722 - D0279. Programmed cell death pathways in sodium iodate-induced retinal degeneration Volker Enzmann; Jasmin Balmer; Rahel Zulliger; Sebastian Wolf View Presentation 723 - D0280. Sodium Iodate Induces Rapid Neuroretinal Dysfunction Prior To RPE Changes Jinmei Wang; Jared Iacovelli; Carrie Spencer; Magali Saint-Geniez View Presentation 724 - D0281. A New Immunodeficient Pigmented Retinal Degenerate Rat Strain To Study Transplantation of Human Cells Magdalene J. Seiler; Robert B. Aramant FARVO; Gabriel Nistor; Melissa K. Jones; Dave Ferguson; Elizabeth Bryda; Hans S. Keirstead View Presentation 725 - D0282. A rat model of retinal degeneration induced by intraocular injections of CNF1 toxin Enrica Strettoi; Viviana Guadagni; Chiara Cerri; ilaria piano; Antonella Caputo; Elena Novelli; Carla Fiorentini; Claudia M. Gargini; Matteo Caleo View Presentation 726 - D0283. Damage of Inner Retinal Cells Induced by Neurotoxic Effect of Glutamate Receptor Agonists Pedro de la Villa; Estella Calvo; Laura Ramirez; Francisco Germain; Violeta GomezVicente; Nicolas Cuenca View Presentation 727 - D0284. Optical coherence tomography, electroretinography, and histological analysis of mouse models for retinal degeneration Tomoko Hasegawa; Hanako O. Ikeda; Noriko Nakano; Yuki Muraoka; Nagahisa Yoshimura View Presentation 728 - D0285. Ocular Blast Trauma in the DBA/2J Mouse Courtney Bricker-Anthony; Jessica Hines-Beard; Lauren D'Surney; Eldon E. Geisert; Tonia S. Rex View Presentation 729 - D0286. Delayed treatment with erythropoietin protects against ocular trauma Jessica Hines-Beard; Lauren D'Surney; Brendan Lunn; Courtney Bricker-Anthony; Tonia S. Rex View Presentation 730 - D0287. The P2X4 Receptor and NTPDase1/CD39 Enzyme are Expressed in the Mouse Retina and are Up-regulated in Retinal Degeneration Tracy Ho; Kirstan A. Vessey; Andrew I. Jobling; Erica L. Fletcher View Presentation Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 36 sur 222 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 731 - D0288. Canine Model of Autosomal Recessive Complete-type Congenital Stationary Night Blindness Mineo Kondo; Ryoetsu Imai; Tomio Nakashita; Miho Imawaka; Kosuke Ueda; Hirohiko Ohtsuka; Shinji Ueno; Gautami Das; Keiko Miyadera; Gustavo D. Aguirre View Presentation 732 - D0289. Differential Expression of IRBP, Albumin, BIGH3 and PNA Binding in the Interphotoreceptor Matrix Versus Choroid in Diabetes, AMD and Glaucoma Federico Gonzalez-Fernandez; Tianle Zou; Richard Lebaron; Andrew T. Tsin; John Lonsdale View Presentation 733 - D0290. Earliest manifestation of MERTK mutation: Abnormal ERG recovery after brief exposure to moderate light in very young RCS rats Sergey Girman; Shaomei Wang View Presentation 734 - D0291. Impaired formation of RD3-GCAP1-GC1 complex causes Leber congenital Amaurosis type1 Seifollah Azadi; Rahel Zulliger; Robert S. Molday; Muna I. Naash View Presentation 133. Oculoplastics and Orbital Disease: Surgical and Therapeutic Techniques Moderator(s): Ann Murchison (Wills Eye Institute) 10:30 AM - 12:15 PM; Exhibit / Poster Hall 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 10:30 AM - 12:15 PM 735 - D0394. Isolation and Characterization of Stem Cells from Human Orbital Adipose Tissues Szu-Yu Chen; Megha A. Mahabole; Elan L. Horesh; Sara T. Wester; Jeffrey L. Goldberg; Scheffer C. Tseng View Presentation 736 - D0395. Anterior Segment OCT as surgical success biomarker of Laser Dacryocystorhinostomy in lacrimal duct obstruction Cristian Dalmasso; J Aritz Urcola; Javier Cabrerizo; Jesus Hueto; Raquel Cobos View Presentation 737 - D0396. Factors Influencing The Oculocardiac Reflex During Enucleation Steven J. Ryder; Gary J. Lelli View Presentation 738 - D0397. Sequelae in the Treatment of Epiphora with Endoscopic Dacryocystorhinostomy Ann P. Murchison; Jurij R. Bilyk View Presentation 739 - D0398. Para-nasal Sinus Lacrimal Diversion in Patients with Epiphora Resulting from Complete Canalicular Obstruction and/or functional epiphora in the setting of a patent lacrimal system with a new stent Guillermo Salcedo; Brian Willoughby; Hugo Quiroz-Mercado; Ariel Ceriotto; Ania Buigues View Presentation 740 - D0399. Transconjunctival vs. Lateral orbitotomy approach for retrobulbar intraconal orbital cavernous hemangioma - a comparative study of long term outcomes Renbing Jia; Xianqun Fan View Presentation 741 - D0400. Safety of Botulinum Neurotoxin Injection to the Central Upper Eyelid and Eyebrow Regions Lily Y. Huang; Bryan R. Costin; Natta Sakolsatayadorn; Julian D. Perry View Presentation 742 - D0401. Results of Combined Multispecialty Endoscopic Dacryocystorhinostomy Charles Kim; Ashutosh Kacker; Aaron N. Pearlman; Gary J. Lelli View Presentation 743 - D0402. A Comparison of Techniques of Reducing Oculofacial Surgical Field Fire Risk Due to Oxygen Payam Morgan; Kristin E. Hirabayashi; Jeffery Joseph; Jeremiah Tao View Presentation 744 - D0403. An algorithm to guide canthotomy/cantholysis by emergency personnel Benjamin P. Erickson; Wendy W. Lee View Presentation 745 - D0404. Implants for Orbital Fractures, Is a question of time? Ana I. Ortiz; Fabiola Ogaz; Ramiro O. Prieto; Ania Buigues; Guillermo Salcedo View Presentation 746 - D0405. Post Operative Diplopia and Enophthalmos After Orbital Fracture Repair Shivani Kamat View Presentation 747 - D0406. Preservation of the inferomedial strut in endoscopic orbital decompression for thyroid orbitopathy reduces the rate of postoperative diplopia Nahyoung G. Lee; Benjamin Bleier; Suzanne K. Freitag View Presentation 748 - D0407. Diffusion of Retrobulbar Injections: a Pilot Study in Patients Undergoing Enucleation Shu-Hong Chang; Sheila Goyal; Arash Jian-Amadi; Michael C. Chappell View Presentation 749 - D0408. The Effect of Sub-Tenon Injections on Increasing Optic Nerve Length Excision during Enucleation: Case Control Trial in Fresh Frozen Human Cadavers Tal Rubinstein; Natta Sakolsatayadorn; Bryan R. Costin; Stephen A. McNutt; George Trichonas; Jennifer M. McBride; Julian D. Perry View Presentation 750 - D0409. The Use of Nerve Stimulators for Patients with Bell's Palsy Ameet K. Goyal; Shivani Goyal View Presentation 134. Pharmacological Interventions; Cellular Mechanisms; Electrophysiology Moderator(s): Stuart Graham (Macquarie University) and Ursula Schlotzer-Schrehardt (University of Erlangen-Nürnberg) 1:00 PM - 2:45 PM; Exhibit / Poster Hall 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM View Session Details View Session Details 751 - A0086. Down-regulation of the RNA editing enzyme ADAR2 contributes to RGC death in a mouse model of glaucoma Ai Ling Wang; Scott A. Nawy View Presentation 752 - A0087. Ocular hypotensive efficacy and safety of a fixed dose combination of AR12286 (a Rho Kinase Inhibitor) and travoprost Brian Levy; Richard A. Lewis; Casey Kopczynski; Thomas J. Van Haarlem; Gary D. Novack View Presentation 753 - A0088. Activation of the complement system in an autoimmune model of glaucoma Sabrina Reinehr; Sebastian Becker; Sandra Kuehn; Christina Casola; Rozina Noristani; Burkhard H. Dick; Stephanie C. Joachim View Presentation 754 - A0089. Evaluation of AR-13324, a novel dual mechanism agent, in lowering of IOP in glaucoma and ocular hypertension Mark Weiss; Brian Levy; Casey Kopczynski; Thomas J. Van Haarlem; Gary D. Novack View Presentation 755 - A0090. gp130 Expression and Activation as a Function of Age and IOP in the DBA/2 Mouse Model of Glaucoma Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 37 sur 222 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM Franklin D. Echevarria; Michelle Won; Caroline Walker; Heather Cathcart; Rebecca M. Sappington View Presentation 756 - A0091. In vivo imaging of mitochondrial axonal transport in the diseased and aged mammalian CNS Yuji Takihara; Masaru Inatani; Kei Eto; Toshihiro Inoue; Keiichiro Iwao; Yoshihiro Takamura; Junichi Nabekura; Hidenobu Tanihara View Presentation 757 - A0092. Impact of supply problems of preservative-free and low preservative glaucoma medications on patients and hospital staff Shima Shah; Julia E. Theodossiades View Presentation 758 - A0093. Evaluation of the antioxidant status of human aqueous humor Carla J. Siegfried; Ying-Bo Shui; Fang Bai; David C. Beebe View Presentation 759 - A0094. Drug therapy of magnesium deficiency in patients with primary open angle glaucoma (POAG) lusine arutyunyan; Elena Iomdina View Presentation 760 - A0095. Prostaglandin Efficacy in the Hispanic Population Lindsay T. Davis; Kundandeep Nagi; Dip S. Jadav View Presentation 761 - A0096. Short-term Intraocular Pressure Spike after Combined Phacoemulsification and iStent Implantation: Prednisolone versus Loteprednol Qianqian Wang; Paul Harasymowycz View Presentation 762 - A0097. Association between Genetic Polymorphisms of the Prostaglandin F2α Receptor Gene and Response to Latanoprost in Glaucoma and Ocular Hypertension Patients Kazuhisa Sugiyama; Mayumi Sakurai; Tomomi Higashide; Shinji Ohkubo; Hisashi Takeda; Yoshiaki Saito View Presentation 763 - A0098. Connective Tissue Growth Factor Induction of Lysl Oxidase (LOX) Enzyme Expression in Human Trabecular Meshwork Cells is reduced by FG-3019 Deborah M. Wallace; Abbot F. Clark; Noelynn Oliver; John K. Crean; Colm J. O'Brien View Presentation 764 - A0099. The retinal pigmented epithelial cell and peripapillary atrophy: potential mediators of glaucomatous optic disc cupping? Emily L. Hughes; Neil G. Docherty; John K. Crean; Abbot F. Clark; Deborah M. Wallace; Colm J. O'Brien View Presentation 765 - A0100. Ocular Pharmacokinetics of ISV-215 (Bimatoprost 0.03%) Formulated in a DuraSite Delivery System Compared to Lumigan in Rabbits Lyle M. Bowman; Afshin Shafiee; Eddie Hou; Kamran Hosseini View Presentation 766 - A0101. Agonist activity and binding affinity of ONO-9054 to EP3 and FP Receptors Shinsaku Yamane; Satoshi Nakayama; Tomohiro Karakawa; Shintaro Nakao; Tsutomu Shiroya; Yutaka Shichino View Presentation 767 - A0102. Grp94 and Grp78 can triage distinct mutant myocilin species for clearance or for aggregation Chad A. Dickey; Shannon E. Hill; Stanislav I. Tomarev; Myung Kuk Joe; Raquel L. Lieberman; Amirthaa Suntharalingam View Presentation 768 - A0103. EFFECT OF LOSARTAN ON FACTORS RELATED TO HEALING PROCESS IN RABBIT TENON'S FIBROBLASTS Carolina Modulo; Marco Andrey C. Frade ; Peter Reinach; Eduardo M. Rocha; Jayter S. Paula View Presentation 769 - A0104. Reduction by tissue plasminogen activator (tPA) of steroid-induced intraocular pressure (IOP) elevation in sheep Oscar A. Candia; Rosana Gerometta; John Danias View Presentation 770 - A0105. Upregulation of miR-146a in retina in rodent models of elevated intraocular pressure Guorong Li; Mohammadali Almasieh; Coralia C. Luna; Jianming Qiu; Pratap Challa; Molly M. Walsh; Henry Tseng; David L. Epstein; Adriana Di Polo; Pedro Gonzalez View Presentation 771 - A0106. Reduction in Long-term Vision Loss with Preoperative Bevacizumab for Neovascular Glaucoma Ramya Swamy, MD, MPH, Vikas Chopra, MD, Srinivas Sadda, MD Doheny Eye Institute, Dept of Ophthalmology, Keck School of Medicine, Los Angeles, CA Ramya N. Swamy; Vikas Chopra; Srinivas R. Sadda View Presentation 772 - A0107. CHANGES IN RETINAL P2X7 RECEPTORS IN A MURINE MODEL OF GLAUCOMA Jesus J. Pintor; Pedro de la Villa; Maria Jesus Perez de Lara View Presentation 773 - A0108. Global assessment of retinal ganglion cell synapses in a mouse model of ocular hypertension Yvonne Ou; Ming Lu; David W. Sretavan; Erik M. Ullian View Presentation 774 - A0109. The TRPV1 Cation Channel Contributes to Stress-Induced Retinal Astrocyte Migration Karen W. Ho; Carl Weitlauf; David J. Calkins View Presentation 775 - A0110. The Effect of Intravitreal Anti-VEGF Therapy on Intraocular Pressure Fred B. Chu; Claire Kiernan; Norbert Becker; Anjali S. Hawkins View Presentation 776 - A0111. CX3CR1 signaling modulates retinal ganglion cell degeneration in glaucoma Kevin Breen; Alejandra Bosco; David J. Calkins; Monica L. Vetter View Presentation 777 - A0112. Videographic Assessment of Glaucoma Drops Instillation Antonio Remolina-Villarejo; Gabriel Lazcano-Gomez; Armando Castillejos-Chevez; Jesus Jimenez-Roman; Malik Y. Kahook View Presentation 778 - A0113. Small-molecule inhibitors of sFRP1 Jie J. Zheng View Presentation 779 - A0114. Neurotrophin-4 Promotes Retinal Ganglion Cell Survival Following Neuronal Injury In Thy1-YFP Mice Chendong Pan; Lihua Guo; Evan Berger; Anna M. Demetriades View Presentation 780 - A0115. A twelve-months, randomized, prospective, open-label, parallel-group of in vivo confocal microscopic findings in glaucoma patients treated with bimatoprost 0.01% or bimatoprost 0.03% Michele Figus; Stefano Lazzeri; Chiara Posarelli; Luca Martini; Marco Nardi View Presentation 781 - A0116. Development of a cellular model of human trabecular meshwork to Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 38 sur 222 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM evaluate the role of chemokine ligands in glaucoma Georges KALOUCHE; Céline Boucher; Derock Murielle; Annick Coste; Patrick Avenet; Stéphane Melik-Parsadaniantz; Thomas Debeir; Christophe Baudouin; William H. Rostene; Xavier Vigé View Presentation 782 - A0117. Effect of anecortave acetate (AA) on outflow facility in a mouse model of steroid-induced glaucoma Sandeep Kumar; Shaily D. Shah; Emily R. Deutsch; Hai M. Tang; John Danias View Presentation 783 - A0118. Live imaging of early microglia activation predicts neurodegeneration in chronic glaucoma Alejandra Bosco; Cesar R. Romero; Alexis A. Chagovetz; Michael R. Steele; Kevin Breen; Balamurali K. Ambati; Monica L. Vetter View Presentation 784 - A0119. Elevation of IOP triggers responses from cytokines IL-6 and IL-1β; involvement of both optic nerve head astrocytes and retinal ganglion cells Wennan Lu; Jonathan M. Beckel; Jason C. Lim; Gulab S. Zode; Val C. Sheffield; Alan M. Laties; Claire H. Mitchell View Presentation 785 - A0120. Characterization of Primary Open Angle Glaucomatous Sclera Alex S. Huang; Karen Xuandao Duong-Polk; Christopher Heichel; Felipe A. Medeiros; James D. Lindsey; Robert N. Weinreb View Presentation 786 - A0121. Cleavage of IL-6 receptor alpha as a potential mechanism for IL-6 transsignaling in Glaucoma Payton Russom; Cathryn R. Formichella; Rebecca M. Sappington View Presentation 787 - A0122. Pharmacological Actions of L-cysteine on Isolated Bovine Ciliary Muscles Sunny E. Ohia; Anita Okpobiri; Ya Fatou Njie-Mbye; Jenaye Robinson; Madhura Chitnis; Catherine A. Opere View Presentation 788 - A0123. Effect of Tissue Plasminogen Activator on Outflow Facility of Steroid Injected Mouse Eyes Shaily D. Shah; Sandeep Kumar; Terete Borras; Matthew H. Smith; John Danias View Presentation 789 - A0124. Latanoprost Lowers Intraocular Pressure in Matrix Metalloproteinase 9-null Mice Ramez I. Haddadin; Dong-Jin Oh; Douglas J. Rhee View Presentation 790 - A0125. A rat model of glaucoma induced by circumlimbal ligation Algis J. Vingrys; Hsin-Hua Liu; Christine T. Nguyen; Bang V. Bui; Zheng He View Presentation 791 - A0126. The two- global- flash multifocal ERG (mfERG) in the diagnosis of early macular dysfunction in preperimetric glaucoma Anna A. Ledolter; Margarita G. Todorova; Andreas Schötzau; Anja M. Palmowski-Wolfe View Presentation 792 - A0127. The effect of acute intraocular pressure challenge on retinal oxygen saturation, retinal blood flow and visual function Rachael A. O'Connell; Bang V. Bui; Andrew J. Anderson; Sarah L. Hosking View Presentation 793 - A0128. Motion perception in early glaucoma Anna Francoz; Alessandro Carlini; Catherine Creuzot-Garcher; Patrick Quercia; Thierry Pozzo; Alain M. Bron View Presentation 794 - A0129. Electrophysiologic Correlates of RNFL Thickness in Experimental Glaucoma James N. Ver Hoeve; Charlene B. Kim; Carol A. Rasmussen; Christopher J. Murphy; Brian J. Christian; T Michael Nork View Presentation 795 - A0130. Functional Degeneration of Retinal Ganglion Cells in a Mouse Model of Chronic Ocular Hypertension Hui Chen; Yan Zhao; Liang Feng; Jianhua Cang; John B. Troy; Xiaorong Liu View Presentation 796 - A0131. Retinal ganglion cell dysfunction precedes death in glaucoma suspects Gabriel Luna; Eleonore Savatovsky; Brandon Bosse; Michael Banitt; Olga Shif; Lori M. Ventura; Vittorio Porciatti; William J. Feuer View Presentation 797 - A0132. Evaluation of Pre-perimetric Glaucoma Patients using Short Duration Transient Visual Evoked Potentials (SD-tVEP) Peter H. Derr; Rafael L. Furlanetto; Gustavo De Moraes; Alberto O. Gonzalez Garcia; Celso Tello; Jeffrey M. Liebmann; Robert Ritch View Presentation 798 - A0133. Comparing functional damage by Multifocal ERG and visual fields in all severities of glaucoma sujoy mukherjee; Abhishek Singh; Mahasweta Chowdhury; Aparna Rao View Presentation 799 - A0134. Transgenic mice expressing mutated Tyr437His human myocilin have progressive loss of retinal ganglion cell electrical responsiveness Vittorio Porciatti; Tsung-Han Chou; Xu Yang; Stanislav I. Tomarev View Presentation 800 - A0135. Comparison of Static and Dynamic Contrast Sensitivities with Steady-state Pattern Electroretinography Ratio in Suspected Open Angle Glaucoma Patients Péter Balázs Kocsis; Imre Zsolt Fejes; Andrea Facskó; Márta Janáky View Presentation 801 - A0136. Impact of a notch filter on the detection of glaucomatous damage in POAG compared to controls using the 2-global-flash multifocal ERG Anja M. Palmowski-Wolfe; Margarita G. Todorova; Andreas Schötzau; Anna A. Ledolter View Presentation 802 - A0137. Upregulation of TRPV1 Signaling Boosts RGC Excitation Early in a Mouse Model of Glaucoma Carl Weitlauf; Nicholas J. Ward; Brian J. Carlson; Wendi S. Lambert; David J. Calkins View Presentation 135. Cataract Surgery I Moderator(s): Michael Wormstone (University of East Anglia) 1:00 PM - 2:45 PM; Exhibit / Poster Hall 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM View Session Details 803 - B0027. A Virtual Cataract Surgery Course for Ophthalmologists-in-Training Emily Li; Peter Fay; Paul B. Greenberg View Presentation 804 - B0028. Evaluation of new updates in IOL power calculations after LASIK/PRK Li Wang; Douglas D. Koch View Presentation 805 - B0029. A combined decision and Markov model comparison of the economic burden of cataract surgery for a United States patient in the United States versus medical tourism Ronald L. Rebenitsch; David Camejo; Mahendra Rupani View Presentation 806 - B0030. Reduced Cataract Occurrence Associated with Atypical Antipsychotic Use Kaivon Pakzad-Vaezi; Mahyar Etminan; Frederick S. Mikelberg Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 39 sur 222 View Presentation 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 807 - B0031. Aesthetic comparison of topical versus subtenon's anesthetic techniques used in cataract surgeries Philemon K. Huang; Chandra K. Mohan; Lekha Gopal View Presentation 808 - B0032. Visual Performance of Pseudophakic Eyes Corrected for Spherical and Chromatic Aberrations with an Achromatic Intraocular Lens Henk A. Weeber; Roland Pohl; Ulrich Mester; Patricia A. Piers View Presentation 809 - B0033. A Study of the Eye Dynamics and Vision in Patients with Diabetes Mellitus Type 2 and their Relationship with Blood Glucose Levels Lydia Mineeva; Irina Slezkina View Presentation 810 - B0034. A comparison between Casey Eye Institute (CEI) camera system and the EAS-1000 camera in recording retro-dot opacities Natsuko Hatsusaka; Kazuyuki Sasaki; Hiroshi Sasaki View Presentation 811 - B0035. Ophthalmic air filtration practices in hospital and community settings and its role in modern day surgery Kelly Ma; Bonnie A. Henderson View Presentation 812 - B0036. Evaluation of an Intraoperative Anterior Segment Biometric System Ajay Pillai; Dustin Morley; Richard T. Olmstead View Presentation 813 - B0037. Evaluation of Cataracts using Fundus Reflex Photographs in the AgeRelated Eye Disease Study 2 (AREDS2) Erika Treichel; Amitha Domalpally; Ronald P. Danis; Susan B. Reed; Ashwini R. Narkar; Traci E. Clemons; Emily Y. Chew View Presentation 814 - B0038. Predicting IOL Position from Pre-op A-scan Data Ashraf M. Mahmoud; Li Wang; Cynthia J. Roberts; David Castellano; Mitchell P. Weikert; Douglas D. Koch View Presentation 815 - B0039. Relationship between the Eye's Refractive Cylinder and Anterior and Total Corneal Cylinder Nic J. Reus; Rob G. van der Heijde; Victor A. Sicam View Presentation 816 - B0040. Cataract Surgery in Forme Fruste Megalocornea Nisha Warrier; Mary K. Daly; Donna Siracuse-Lee View Presentation 817 - B0041. Morphological Iris Analysis Using OCT Visante in Tamsulosin Users Edgardo M. Barraza; Cristina Mendoza; Marina Flores Baca; Laura Leticia ArroyoMuñoz; Oscar Guerrero-Berger; Ana Beatriz Medina; Adan Tapia Martinez; Claudia Palacio View Presentation 818 - B0042. IOL calculation after hyperopic refractive treatments–case report Eva Juhasz; Tamas Filkorn; Kinga Kranitz; Gábor László L. Sándor; Illes Kovacs; Andrea Gyenes; Lorant Dienes; Zoltan Z. Nagy View Presentation 819 - B0043. Fibronectin Adhesive Properties of Various Intraocular Lens Materials Marcia Ong; Lixin Wang; Mutlu Karakelle View Presentation 820 - B0044. Development and Evaluation of an Objective Cataract Grading Metric Dustin Morley; Ajay Pillai; Richard T. Olmstead View Presentation 821 - B0045. Impact of Pre-operative Anterior Chamber Depth and Axial Length on Cataract Surgery Outcomes: Results of the Ophthalmic Surgical Outcomes Data Project Amy Chomsky; Nakul Shekhawat; Elizabeth Baze; Mary K. Daly; David E. Vollman; Mary G. Lawrence View Presentation 822 - B0046. Predictive values of three different formulas for Intraocular lens implantation in eyes with high myopia Miriam Lopez-Salas; Jesus Arrieta-Camacho; Arturo J. Ramirez-Miranda; Eduardo Chavez-Mondragon View Presentation 823 - B0047. Comparison of Predicted versus Actual Refractive Outcome Using Two Commercially Available Biometers Shahed Ghoghawala; Sumit Garg; Matthew Wade; Roger F. Steinert View Presentation 824 - B0048. Is the A constant for the SRK/T formula the same for the right and left eyes of patients having bilateral surgery? John C. Merriam; Lei Zheng View Presentation 825 - B0049. Spherical Aberrations in Singaporean Chinese Population Using the KR1W Wave Front Analyzer Arlie Jaurigue; Soon Phaik Chee View Presentation 136. IOL and Crystalline lens Moderator(s): Geunyoung Yoon (University of Rochester) and Jim Schwiegerling (University of Arizona) 1:00 PM - 2:45 PM; Exhibit / Poster Hall 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM View Session Details 826 - B0050. Straylight in Pseudophakes for Different Intraocular Lens Types Luuk Franssen; Marrie Van der Mooren; Burkhard H. Dick; Ulrich Mester; Patricia A. Piers View Presentation 827 - B0051. Binocular through-focus image quality with various combinations of modified monovision Guillaume Van Der Meer; Pierre-Jean Pisella; Richard Legras View Presentation 828 - B0052. Influence of Pupil Diameter on Intraocular Scattering Measurements Based on Double Pass Images in Patients with Different Types of Cataracts Jaume Pujol; Juan Carlos Ondategui Parra; Joan A. Martinez-Roda; Meritxell Vilaseca; Mouafk Asaad Ammaar View Presentation 829 - B0053. Capsular Adhesion to Intraocular Lens Evaluated In Vivo Using Ultralongscan-depth Optical Coherence Tomography Yinying Zhao; Jin Li; Weilin Lu; Xiaoying Xing; Fan Lu; Yune Zhao View Presentation 830 - B0054. Restoration of acrylic intraocular lens injected through cartridge Makoto Inoue; Jiro Hidaka; Akito Hirakata View Presentation 831 - B0055. Stability of the human crystalline lens measured with a high temporal resolution dynamic Purkinje-meter system Juan Tabernero; Antonio Fernández; Pablo Artal View Presentation 832 - B0056. Rotational stability of two single-piece toric acrylic intraocular lenses Gernot Steinwender; Navid Ardjomand Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 40 sur 222 View Presentation 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 833 - B0057. Multicenter clinical evaluation of an aspheric diffractive multifocal one-piece IOL Daniel H. Chang; Elizabeth A. Davis View Presentation 834 - B0058. Light Transmittance of Explanted Hydrophobic Acrylic Intraocular Lenses with Surface Light Scattering Liliana Werner; Caleb Morris; Shannon Stallings; Erica Liu; Anne M. Floyd; Andrew Ollerton; Lisa Leishman; Zachary Bodnar; Marcia Ong; Ali Akinay View Presentation 835 - B0059. Visual Simulation of Retinal Images through a New Asymmetric Refractive Multifocal Intraocular Lens with Two Spherical Surfaces Yuki Hidaka; Kazuno Negishi; Kazuhiko Ohnuma; Kazuhiro Watanabe; Hidemasa Torii; Megumi Saiki; Kazuo Tsubota View Presentation 836 - B0060. A novel hydrophilic intraocular lens with lateral walls to prevent posterior capsular bag opacification Hiroyuki Matsushima; Koichiro Mukai; Satoshi Watabiki; Yoko Katsuki; Jiro Hidaka; Senoo Tadashi View Presentation 837 - B0061. Curvature Changing Accommodating IOL Jim Schwiegerling; Sean J. McCafferty; William Duncan View Presentation 838 - B0062. A triplet optical design for a wide range accommodative IOL Enrique-Josua Fernandez; Pablo Artal View Presentation 839 - B0063. Optical Ensemble Analysis of the Potential Optical Performance of Aspheric Multifocal Toric IOLs Huawei Zhao View Presentation 840 - B0064. Visual outcomes after implantation of a new trifocal intraocular lens Luis Izquierdo; Maria A. Henriquez; Mauricio Rodriguez View Presentation 841 - B0065. Visual outcomes and patient satisfaction after cataract surgery with a diffractive trifocal intraocular lens Javier García Bella; Jose Vazquez-Molinin; Laura Valcarce; Jesus Carballo; Juan Velez; Juan Carlos Sanz; Vicente Polo; Jose M. Martinez de la Casa View Presentation 842 - B0066. Monochromatic Higher Order Aberrations in Patients Undergoing Cataract Surgery with an Aspheric Intraocular Lens Douglas A. Lyall; Sathish Srinivasan; Lyle Gray View Presentation 843 - B0067. Non-invasive Evaluation of Intraocular Lens Performance Patricia A. Piers; Sanjeev Kasthurirangan; Basilios Sideris View Presentation 844 - B0068. Predicted changes in the cut surface and weight of colored acrylic intraocular lenses in 20 years Kenji Kawai View Presentation 845 - B0069. Safety and clinical results of posterior chamber phakic intraocular lens implantation in low anterior chamber depth Min gyu Lee; Dong Hui Lim; Eui Sang Chung; Tae-Young Chung View Presentation 846 - B0070. Comparative study of visual performance of two multifocal intraocular lens : two-year follow-up Balmitgère Thomas; Burillon Carole View Presentation 847 - B0071. Proposed novel schematic eye model for testing intraocular lens performance Cristina Mendoza; Anabel S. Sanchez-Sanchez; Omar Teran-Jimenez; David Rivera; Claudia Palacio; Laura Leticia Arroyo-Muñoz; Oscar Guerrero-Berger; Ernesto Suaste Gomez View Presentation 848 - B0072. Schematic eye model based on the regression of age-dependent changes of the crystalline lens Takushi Kawamorita; Hiroshi Uozato; Hiroshi Sasaki; Yuko Shibata; Masatsugu Kanazawa; Masakazu Hirota; yoona jang; Shinji Arai; Kimiya Shimizu View Presentation 849 - B0073. Comparative Analysis of Residual Astigmatism Induced by a Single-piece or Three-piece Intraocular Lens after Cataract Surgery Jin Kwon Chung; Mee Kum Kim; Won Ryang Wee View Presentation 850 - B0074. Impact of Ultrasound Biomicroscopy (UBM) versus White-to-White (WTW) measurement on sizing of Visian Implantable Collamer Lens (ICL) and Residual Postoperative Refraction Puneet Panda; Ann Ostrovsky; Scott E. Brodie; Mark Speaker View Presentation 851 - B0075. Measurement of the intraocular scattering in cataractous patients, using different instruments and parameters. Comparative study Juan Carlos Ondategui Parra; Lorena Mateos-Pena; Joan A. Martinez-Roda; Montserrat Arjona View Presentation 852 - B0076. Square-Edge IOLs and Epithelial Lens Cell Proliferation: Implication on Posterior Capsule Opacification in an in Vitro Model Eleonora Favuzza; Iacopo Paladini; Ugo Menchini; Rita Mencucci View Presentation 853 - B0077. visual impact of micro-vacuole defect in intraocular lenses Marrie Van der Mooren; Michelle Langeslag; George Beiko; Patricia A. Piers View Presentation 854 - B0078. Evaluation of the Impact of Scatter in Pseudophakic Eyes with Glistenings Anand Doraiswamy; Edward DeHoog View Presentation 855 - B0079. In vitro straylight levels for IOLs across forward scatter positions up to 30 degrees Michelle Langeslag; Marrie Van der Mooren; Patricia A. Piers; Luuk Franssen View Presentation 856 - B0080. Optical simulation for sub-surface nano glistening Yoriko Takahashi; Takushi Kawamorita; Norihiro Mita; Natsuko Hatsusaka; Eri Shibuya; Eri Kubo; Hiroshi Sasaki View Presentation 137. Cornea and Cataract Moderator(s): Hari Jayaram (NIHR Biomed Rsrch Ctr for Ophthal) and Sheila West (Johns Hopkins Wilmer Eye Inst) 1:00 PM - 2:45 PM; Exhibit / Poster Hall 1:00 PM - 2:45 PM View Session Details 857 - B0081. Insurance, race, gender and how they relate to visual acuity at the time of cataract surgery Michelle Oboite; Sandra Stinnett; Alan N. Carlson; Natalie A. Afshari Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 41 sur 222 View Presentation 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 858 - B0082. PRECOG: Validating the early assessment of vision after cataract surgery Nathan G. Congdon; Xixi Yan; Van C. Lansingh; Ving F. Chan; Andreas Mueller; Ling Jin; Mirjam E. Meltzer; Sasipriya Karumanchi; Chunhong Guan; Alemayehu Sisay View Presentation 859 - B0083. The impact of first and second eye cataract surgery on hospitalisation from injuries due to a fall: a whole population study Lynn Meuleners; Michelle Fraser; Jonathon Ng; Nigel Morlet View Presentation 860 - B0084. Prevalence of Corneal Astigmatism in a Cataract Population David Curragh; Patrick Hassett View Presentation 861 - B0085. Contrast acuity in eyes with different types of lens opacity mai takahashi; Hiromi Osada; Norihiro Mita; Eri Shibuya; Natsuko Hatsusaka; Yoriko Takahashi; Yasuo Sakamoto; Kazuyuki Sasaki; Eri Kubo; Hiroshi Sasaki View Presentation 862 - B0086. Visual Outcomes of Intraocular Lens Exchange and Repositioning Raisa Epistola; Deana Choi; Mark A. Slabaugh View Presentation 863 - B0087. Factors Influencing Visual Function in Eyes with Retrodots by Difference in Size Nagai Kota; Norihiro Mita; Natsuko Hatsusaka; Ryumon Honda; Kazuyuki Sasaki; Hiroshi Sasaki View Presentation 864 - B0088. Correlating visual function and size of area opacified by retrodots based on retro-illumination photography Hiroshi Sasaki; Norihiro Mita; Natsuko Hatsusaka; Eri Shibuya; Mai Sasaki; mai takahashi; Yoriko Takahashi; Hiromi Osada; Kazuyuki Sasaki; Eri Kubo View Presentation 865 - B0089. Donor Cornea Characteristics in Relation to Microbiologic Culture Results and Postkeratoplasty Infections Vandana C. Reddy; Rafael de Melo Franco; Maria A. Woodward; Indu Vadakkepattath; Michael O'Keefe; Roni M. Shtein View Presentation 866 - B0090. Geomapping Ophthalmomyiasis using Google Earth: Utilizing Geographic Information Systems in Ophthalmology Omar Ozgur; Paul Latkany; David Della Rocca; Robert Della Rocca; Elizabeth Maher View Presentation 867 - B0091. Infectious Keratitis in Mexico: 10 year experience in corneal scrapes Enrique O. Graue-Hernández; Julio C. Hernandez-Camarena; Patricia Chirinos-Saldaña; Alejandro Navas; Arturo J. Ramirez-Miranda; Mariana Ortiz-Casas; Nadia Luz LópezEspinosa; Lizet Vizuet-García; Victor M. Bautista View Presentation 868 - B0092. Incision height and trichiasis recurrence in bilamellar tarsal rotation surgery Shannath L. Merbs; Kathleen C. Oktavec; Sandra D. Cassard; Beatriz E. Munoz; Sheila K. West; Emily W. Gower View Presentation 869 - B0093. The Epidemiology of Lower Eyelid Trachomatous Trichiasis among Upper Eyelid Trichiasis Surgery Patients Sandra D. Cassard; Shannath L. Merbs; Jennifer C. Harding; Beatriz E. Munoz; Sheila K. West; Emily W. Gower View Presentation 870 - B0094. Outcomes of Repeat Trichiasis Surgery Emily W. Gower; Sandra D. Cassard; Shannath L. Merbs; Jennifer C. Harding; Beatriz E. Munoz; Sheila K. West View Presentation 871 - B0095. Decline of ocular Chlamydia trachomatis infection and follicular trachoma with annual rounds of mass treatment in mesoendemic communities in Tanzania Jennifer S. Lee; Beatriz E. Munoz; Harran A. Mkocha; Charlotte Gaydos; Sheila K. West View Presentation 872 - B0096. Corneal Transplantation in Mexico: Future Perspectives Aida Jimenez-Corona; Alejandro Claros; Arturo J. Ramirez-Miranda; Alejandro Navas; Tito Ramirez-Luquín; Victor M. Boullosa; Enrique O. Graue-Hernández View Presentation 873 - B0097. Scleritis Associated with Relapsing Polychondritis Luis Gonzalez; Maite Sainz de la Maza; Nicolas Molina-Prat; Daniel Rojas Crutchik; Priyanka P. Doctor; Joseph Tauber; C. Stephen Foster View Presentation 874 - B0098. Pachymetry Average in a Hispanic Population Judith Zavala; Jorge E. Valdez; Ubaldo Martínez; Carlos-Alberto Rodríguez-Barrientos; Guillermo Mendoza View Presentation 875 - B0099. Molecular Detection of etiologic agents of infectious blepharitis and its association with systemic diseases Ingrid V. Gonzalez Leon; Oscar Fernandez-Vizcaya; Maria F. Mena-Castell; Cecilia Chavez-España; Victor Moctezuma-Baltazar; Atzin Robles-Contreras; Hector J. PerezCano View Presentation 876 - B0100. Clinical and Microbiological Profile of infectious Keratitis in Children AURELIANO MORENO-ANDRADE; Arturo J. Ramirez-Miranda; Alejandro Navas; Julio C. Hernandez-Camarena; Lizet Vizuet-García; Carolina Gaona-Juárez; Victor M. Bautista; Mariana Ortiz-Casas; Luis Antonio Bautista-Hernandez; Enrique O. GraueHernández View Presentation 877 - B0101. Prevalence of dry eye disease in elderly individuals of the French population (the MONTRACHET Study) Aurore Muselier-Mathieu; Cyril Meillon; Caroline Fiet; Sandrine Vinault; Christine Binquet; Benigne Mathieu; Christophe Tzourio; Alain M. Bron; Catherine P. Garcher View Presentation 878 - B0102. INCIDENCE OF CORNEAL DYSTROPHIES AT NUESTRA SEÑORA DE LA LUZ HOSPITAL FOUNDATION, A 5 YEAR-EPIDEMIOLOGICAL REVIEW Manuel García; Oscar Baca; Alejandro Babayan; Cristina Pacheco-Del-Valle; Regina Velasco View Presentation 879 - B0103. Clinical outcomes and prognostic factors associated with Acanthamoeba keratitis treated with pentamidine isethionate Jane Y. Huang; Hiroaki Ozaki; Naoyasu Umeda; Aki Fuchigami; Masahiko Kozawa; Eiichi Uchio View Presentation 880 - B0104. Genetic diversity among Acanthamoeba sp. isolated from clinically suspected cases of Amoebic keratitis patients attending a tertiary care hospital and proteomic differntiation between the trophozoite and cyst stage of Acanthamoeba Himansu S. Behera; Gita Satpathy; Anita Panda; Pooja Bandivadekar; Niranjan Nayak; Tushar Agarwal; Murugesan Vanathi View Presentation 881 - B0105. The Proctor experience with Acanthamoeba Keratitis from 1996 - 2012 Elizabeth M. Grace; Vicky Cevallos; Todd P. Margolis; Nisha Acharya; Thomas M. Lietman; Jeremy D. Keenan View Presentation 882 - B0106. Familial Corneal Patterns in Pellucid Marginal Degeneration (PMD): Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 42 sur 222 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM Uncovering a Possible Etiology Hajirah N. Saeed; Charles S. Bouchard View Presentation 883 - B0107. Cytokines in tear fluid of patients undergoing keratoplasty Aki Fuchigami; Kyoko Nakajima; Jane Y. Huang; Masahiko Kozawa; Eiichi Uchio View Presentation 884 - B0108. National Survey of Pellucid Marginal Corneal Degeneration in Japan Jun Shimazaki; Naoyuki Maeda; Osamu Hieda; Yuichi Ohashi; Akira Murakami; Kohji Nishida; Kazuo Tsubota View Presentation 885 - B0109. Topometric Indices In Unilateral Keratoconus Patients oktay diner; Volkan Hurmeric; Osman M. Ceylan; Umit Yolcu View Presentation 886 - B0110. Acute and long term ocular manifestations of Stevens-Johnson syndrome and toxic epidermal necrolysis syndrome in children Caroline Catt; Kamiar Mireskandari; Asim Ali View Presentation 887 - B0111. Persistent Corneal Epithelial Defect After Pars Plana Vitrectomy Chi-Chin Sun; Hsi-Fu Chen; Ling Yeung View Presentation 888 - B0112. Ophthalmology/Optometry Allergic Rhinoconjunctivitis Patient Treatment; The Allergies, Immunotherapy & RhinoconjunctivitiS (AIRS) Provider Survey Leonard Bielory; Mark Dykewicz; Timothy Craig; Michael Blaiss; Bryan Leatherman; David Skoner; Nancy E. Smith; F. Allen-Ramey View Presentation 889 - B0113. Epidemiology of Scleritis and Episcleritis: Results from the Pacific Ocular Inflammation Study Gelareh Homayounfar; Vivien M. Tham; Natalie Nardone; John V. Parker; Aleli C. Vinoya; Aileen R. Uchida; Nisha Acharya View Presentation 890 - B0114. Indications for and causes of enucleation in a rural United States population Daniel W. Upton; Xiaoqin Tang; Tamara R. Vrabec; Wells Reinheimer View Presentation 891 - B0115. Anterior Chamber Angles measured by van Herick’s Method and Anterior Segment Optical Coherence Tomography (OPKO Spectral OCT SLO™) in Patients seen in Optometric Practice in Norway Frode Larsen; Knut Luraas; Per O. Lundmark View Presentation 892 - B0116. Effects of tropicamide and phenylephrine on iris dilation and blood pressure in adults with and without hypertension Julian Tokarev; Elena Bitrian; Richard Manka View Presentation 893 - B0117. Anterior vitrectomy at the time of cataract surgery: A whole-population study of the incidence and consequences Jonathon Ng; Nigel Morlet; Antony Clark View Presentation 894 - B0118. Phenotyping and genotyping of Staphylococcus aureus on ophthalmology clinic surfaces Rachel E. Reem; Joany Van Balen; Armando E. Hoet; Colleen M. Cebulla View Presentation 895 - B0119. Dietary Glycemic Index and Risk of Age-Related Cataract: Findings from Andhra Pradesh Eye Disease Study Rohit C. Khanna; Suneetha Sapur; Krishnaiah Sannapaneni; Gullapalli N. Rao View Presentation 896 - B0120. Association between statin use and risk of developing cataracts Nathan Carpenter; Samuel K. Lohstreter; Michelle Y. Cho; James R. Beal View Presentation 897 - B0121. Inflammatory and Oxidative Stress Markers and the 20-Year Cumulative Incidence of Age-Related Cataract: the Beaver Dam Eye Study Barbara E. Klein; Chelsea E. Myers; Karen J. Cruickshanks; Kristine E. Lee; Ronald Klein View Presentation 898 - B0122. Prevalence of cataract and its main comorbidities in a Hispanic population JOSE A. NAVA; Alejandro Tamez; Nelly A. Torres; Jose D. Martinez; Juan F. LozanoRamirez; Jorge E. Valdez View Presentation 899 - B0123. Role of ephrin genes in cortical cataract pathogenesis Ekaterina Yonova; Abhishek Nag; Cristina Venturini; Pirro G. Hysi; Katie M. Williams; Tim Spector; Christopher J. Hammond View Presentation 138. Dry Eye and Lacrimal Gland I Moderator(s): Kazuo Tsubota (Keio Univ School of Medicine) and Michael Stern (Allergan, Inc) 1:00 PM - 2:45 PM; Exhibit / Poster Hall 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM View Session Details 900 - B0205. Does Altering the Volume of an Artificial Tear Applied to the Eye Influence Vision? William H. Ridder; Monisha Paripatyadar; Lisa Wahl View Presentation 901 - B0206. Effects of Omega-3 Fatty Acid and Hyaluronic acid Mixture Eye Drops on the Ocular Surface in Desiccating Stress induced Murine Dry Eye Zhengri Li; Jung-Han Choi; Hyo Seok Lee; Ji-Suk Choi; Han Jin Oh; Kyung Chul Yoon View Presentation 902 - B0207. Evaluation of a Topical Cis-urocanic acid in a Murine CAE™ Model of Dry Eye Disease Andy Whitlock; Laura Belen; Jennifer Brackett; Burkhard Blank View Presentation 903 - B0208. Changes In Corneal Cold Thermoreceptor Activity Induced By Repetitive Allergen Challenges, In A Guinea-Pig Model Of Allergic Conjunctivitis M Carmen Acosta; Carolina Luna; Susana Quirce; Carlos Belmonte; Juana Gallar View Presentation 904 - B0209. Long-Term Corneal Sensitivity after PRK determined by Non-contact Gas Esthesiometry Juana Gallar; Jukka A. Moilanen; M Carmen Acosta; Juha M. Holopainen; Carlos Belmonte; Timo M. Tervo; Waldir Neira View Presentation 905 - B0210. The Ocular Surface Sensory Response to Tear Film Instability With and Without a Contact Lens Carolyn G. Begley; Jun Zhang; Ping Situ; Ziwei Wu; Trefford L. Simpson View Presentation 906 - B0211. Lacrimal gland removal increases primary afferent driven spontaneous blinking and produces ocular hyperalgesia in the rat Ian D. Meng; Stephen T. Barton; Andrew L. Twaite View Presentation 907 - B0212. Alpha Helicity of Lacritin’s C-Terminal Syndecan-1 Binding Domain is Enhanced by Interaction with the Mutual Binding Region in Syndecan-1 Jeff Romano; Jacob Irwin; Inchan Kwon ; Gordon W. Laurie View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 43 sur 222 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 908 - B0213. Lacritin accelerated autophagy promotes clearance of aggregated proteins and is dependent on stress Keith B. Zimmerman; Milton F. Tyler; Ningning Wang; Ronald Raab; Robert L. McKown; Gordon W. Laurie View Presentation 909 - B0214. Lacritin as the Primary Epithelial Survival Activity in Basal Human Tears Reveals Novel Features About Autophagic Survival Signaling Ningning Wang; Ronald Raab; Robert L. McKown; Cindy M. Hutnik; Gordon W. Laurie View Presentation 910 - B0215. Neutralization of Ocular Surface TNF-α Reduces Ocular Surface and Lacrimal Gland Inflammation Induced by In Vivo Dry Eye Yongwoo Ji; Yu Jeong Byun; Jin Sun Kim; Eunae Jeong; Hyung Keun Lee View Presentation 911 - B0216. Protection of barrier function and anti-inflammatory effects of rebamipide in human corneal epithelial cells Hiroshi Tanaka; Ken Fukuda; Waka Ishida; Yosuke Harada; Tamaki Sumi; Atsuki Fukushima View Presentation 912 - B0217. Expression and secreting mechanism of mucins induced by DA-6034 in cultured human conjunctival epithelial cells Tae-im Kim; Hun Lee; Ji Won Jung; Eung Kweon Kim View Presentation 913 - B0218. Regulators of MUC5AC gene expression in conjunctival epithelia of dry eye patients Rosa M. Corrales; Stephen C. Pflugfelder View Presentation 914 - B0219. Decellularization of porcine lacrimal gland tissue for development of a lacrimal gland scaffold Kristina Spaniol; Alexander Kunze; Marco Metzger; Gerd Geerling; Stefan Schrader View Presentation 915 - B0220. Functional rabbit acinar cells cultured on decellularized lacrimal gland scaffold Hui Lin; Guoying Sun; Hong he; Jennifer Elisseeff; Samuel C. Yiu View Presentation 916 - B0221. ENaC in the rabbit lacrimal gland and its changes during Sjögren’s syndrome and pregnancy Chuanqing Ding; Michael Lu; Jianyan Huang View Presentation 917 - B0222. Intermittent fasting prevents lacrimal hypofunction in rat visual display termin user model: a pivotal role of endogenous D-3-hydroxybutyrate Shigeru Nakamura; Ryuji Hisamura; Toshihiro Imada; Kazuo Tsubota View Presentation 918 - B0223. Analysis of chemokines involved in the pathogenesis of dacryoadenitis in mice deficient for programmed cell death-1 Yutaka Sakurai; Masataka Ito; Yoko Karasawa; Yoshihiko Usui; Takaaki Hattori; Hiroshi Goto; Masaru Takeuchi View Presentation 919 - B0224. Potential Regulatory T Cell Mechanisms Of Immune Suppression In A Mouse Model Of Dry Eye Katherine S. Held; Chris S. Schaumburg; Jianping Gao; Larry A. Wheeler; Margarita Calonge; Jerry Y. Niederkorn; Stephen C. Pflugfelder; Michael E. Stern View Presentation 920 - B0225. Minocycline controls clinical outcomes and inflammatory cytokines in moderate and severe meibomian gland dysfunction HUN LEE; Ji Won Jung; Sangyeop Lee; Eung Kweon Kim; Tae-im Kim View Presentation 921 - B0226. Topical administration of L-carnitine on prevention and treatment of murine dry eye Qian Garrett; Xin Zhang; Yu Wang; Peter A. Simmons; Joseph G. Vehige; Jinyang Li; Wei Chen View Presentation 922 - B0227. Effect of Evaporative Stress on Meibomian Gland Proliferative Status and Lipid-Protein Composition Mikhail Geyfman; Jeffrey Suhalim; Tejas N. Shah; Cintia S. De Paiva; Stephen C. Pflugfelder; Eric Potma; James V. Jester View Presentation 923 - B0228. Does EDAR Gene Affect Meibomian Glands Development in Human? Yujing YANG; JianJiang Xu; Jiaxu Hong View Presentation 924 - B0229. Notch regulation of PPAR-gamma and development of meibomian gland dysfunction Mindy K. Call; Katy Fischesser; Matthew O. Lunn; Winston Kao View Presentation 925 - B0230. Tear Meniscus Dimensions and Location of Marx’s Line in Meibomian Gland Dysfunction Jason Feuerman; Stephen C. Pflugfelder View Presentation 926 - B0231. Commensal microflora of eyelid margins and meibomian gland function in normal humans Hua Zhu; Judith L. Flanagan; Nisha S. Yeotikar; Negar Babaei Omali; Daniel Tilia; Shamil Y. Iskandar; Brien A. Holden; Eric B. Papas View Presentation 927 - B0232. Confirmation of Squalene in Tears and Sebum and It’s Potential Function Douglas Borchman; Georgi A. Georgiev; Marta C. Yappert; Norihiko Yokoi View Presentation 928 - B0233. Identification of biomarkers for disease progession of Keratoconus Arkasubhra Ghosh; Rohit Shetty; Lei Zhou; Sharon D'Souza; Roger W. Beuerman View Presentation 929 - B0234. Several Tear Protein Levels Of Breast Cancer Patients Differ from Healthy Participants: A Microarray Study Ksenia Keller; Julia Pieter; Daniel Boehm; Norbert Pfeiffer; Franz H. Grus View Presentation 930 - B0235. Method development for analysis of tear proteins using selected reaction monitoring Simin Masoudi; Ling Zhong; Mark Raftery; Mark D. Willcox View Presentation 931 - B0236. Dry Eye and Systemic Diseases Claudia Henrich; Esen K. Akpek View Presentation 932 - B0237. FODE Highlights Impression Based Mucin Defects on the Ocular Surface in Dry Eye Patients: Kinetics and Retrieval by Tear Lipocalin Po-Ting Yeh; Ben J. Glasgow; Richard Casey View Presentation 933 - B0238. Factors associated with dry eye: The Korea National Health and Nutrition Examination Survey 2010 Tyler Hyung Taek Rim; Ji Min Ahn; Sangchul Yoon; Tae-im Kim; Eung Kweon Kim; Kyoung Yul Seo View Presentation 934 - B0239. Prevalence of asymptomatic dry eye in patients with Collagen Vascular Diseases in South India Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 44 sur 222 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM RAMYA RAVINDRAN; Kalpana Suresh; Varshini Varadaraj View Presentation 935 - B0240. Prevalence and Risk Factors of Dry Eye Disease Among a Hospital-based Population Wei Chen; Jinyang Li; Qinxiang Zheng View Presentation 936 - B0241. Simulation of Acute Symptomatic Exacerbation in Dry Eye (DE) Patients After a Two Hour Exposure to Adverse Conditions in an Environmental Chamber Margarita Calonge; Marisa Tesón; Alberto López-Miguel; Amalia Enriquez-DeSalamanca; Vicente Martín-Montañez; Maria-Jesus Benito; María E. Mateo; Jose M. Herreras; Michael E. Stern; Maria J. Gonzalez-Garcia View Presentation 937 - B0242. Reproducibility of tearfilm osmolarity measurement assessed with electrical impedance in patients with dry eye syndrome and healthy subjects Gerhard Garhofer; Semira Kaya; Johannes Nepp; Doreen Schmidl; Leopold Schmetterer View Presentation 938 - B0243. Comparison of diagnostic tests in distinct well-defined diseases related to dry eye syndrome Monica Alves; Danilo Ribeiro; Jacqueline F. Faustino; Leticia Bachette; Francisco Aranha; Afonso C. Vigorito; Carmino A. De Souza; Jayter S. Paula; Antonio Augusto V. Cruz; Eduardo M. Rocha View Presentation 939 - B0244. The Relationship between Ocular Surface Epithelial Damage and Tear Abnormalities: Osaka Study Hiroaki Kato; Norihiko Yokoi; Aoi Komuro; Yukiko Sonomura; Yuichi Uchino; Miki Uchino; Dogru Murat; Motoko Kawashima; Kazuo Tsubota; Shigeru Kinoshita View Presentation 940 - B0245. Association of Dry Eye Disease with Physical Activity and Sleep Quality: Osaka study Motoko Kawashima; Miki Uchino; Norihiko Yokoi; Yuichi Uchino; Murat Dogru; Aoi Komuro; Yukiko Sonomura; Hiroaki Kato; Shigeru Kinoshita; Kazuo Tsubota View Presentation 941 - B0246. Prospective, Randomized, Multicenter, Double–Blind Placebo–Controlled Study of the Safety and Efficacy of 1% D-3-Hydroxybutyrate eye drop for the Treatment of Dry Eye Tetsuya Kawakita; Etsuko Takamura; Jun Shimazaki; Junko Ogawa; Miki Uchino; Kazumi Fukagawa; Kenichi Yoshino; Mari Tanaka; Machiko Shimmura-Tomita; Kazuo Tsubota View Presentation 942 - B0247. The Korb-Blackie Lid Light Test Donald R. Korb; Caroline A. Blackie View Presentation 943 - B0248. Black-Spot Formation and Fluorescence Tear Break-up Time CHENG-CHUN PENG; Bo Tan; Meng C. Lin; Clayton J. Radke View Presentation 944 - B0249. Surface Chemistry Study Of The Interactions Of Benzalkonium Chloride and Hyaluronic Acid With Meibomian And Corneal Lipids Georgi A. Georgiev; Norihiko Yokoi; Slavyana Ivanova; Rumen Krastev; Zdravko Lalchev View Presentation 945 - B0250. Efficacy of rebamipide for laser in situ keratomileusis-associated dry eye Yosai Mori; Ryohei Nejima; Ayami Masuda; Yoko Maruyama; Keiichiro Minami; Kazunori Miyata View Presentation 946 - B0251. Models for Interaction of the Tear Film with the Corneal and Conjunctival Epithelia Jennifer L. Bruhns; Richard J. Braun; Douglas B. Freeman; Peter E. King-Smith; Padmapriya Ramamoorthy; Jason J. Nichols View Presentation 947 - B0252. A New Paradigm for the Structure of the Tear-Film Lipid Layer Clayton J. Radke; Liat Rosenfeld; Colin Cerrretani; Danielle L. Lieske; Michael Toney View Presentation 948 - B0253. Blood Flow in eye lids and Surface Temperature of TarsalConjunctiva Decreases in Patients with Obstructive MeibomianGland Dysfunction Reiko Arita; Rika Shirakawa; Motoko Kawashima; Kouzo Itoh; Sachiko Inoue; Shiro Amano; Kazuo Tsubota View Presentation 949 - B0254. Mathematical Modeling of Tear Break-up and Fluorescent Intensity Richard J. Braun; Carolyn G. Begley; Adam J. Winkeler; Peter E. King-Smith; Javed Siddique View Presentation 950 - B0255. Effects of Stressed Environments on the Ocular Surface Temperature, Lipid Layer Thickness and Heterogeneity Ranjini Kottaiyan; Gheorghe Salahura; James M. Zavislan; Geunyoung Yoon; James V. Aquavella View Presentation 951 - B0256. Factors Predicting the Ocular Surface Response to Desiccating Environmental Stress Anastasia Alex; Austin Edwards; J. Daniel Hays; Michelle Kerkstra; Amanda Shih; Cintia S. De Paiva; Stephen C. Pflugfelder View Presentation 952 - B0257. The Effects of Cosmetic Eye Pencil Application on the Tear Film and Ocular Surface Alison Ng; Katharine Evans; Rachel V. North; Christine Purslow View Presentation 953 - B0258. Effects of Computer Usage on Tear Film Osmolarity and Precorneal Tear Film Thickness Stephanie Chu; Kelley Bohm; Kristin O. Chapman; Christopher E. Starr View Presentation 954 - B0259. Migration of Substances Applied Around the Eyelid Margin Christine Purslow; Clare Conaty; Alison Ng View Presentation 139. Ocular Surface and Tear Film Moderator(s): Fiona Stapleton (University of New South Wales) and Anthony Bron (University of Oxford) 1:00 PM - 2:45 PM; Exhibit / Poster Hall 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM View Session Details 955 - B0260. Tear Film Biomarker Profiling of Subjects with Dry Eye Disease by Multiplex Analysis Suzanne Hagan; Alan Tomlinson; Louise Madden; Anne Marie Clark; Katherine M. Oliver View Presentation 956 - B0261. Double rows of meibomian gland orifices observed by non-invasive infrared meibography Rika Shirakawa; Reiko Arita; Shima Fukuoka; Satoshi Yamamoto; Kaori Yonehara; Tsuyoshi Haraguchi; Shiro Amano View Presentation 957 - B0262. P-321, a Novel Long-Acting Epithelial Sodium Channel (ENaC) Blocker for the Treatment of Dry Eye Disease Jose L. Boyer; M. Ross Johnson; John Ansede; Karl Donn; Richard C. Boucher; William Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 45 sur 222 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM Thelin View Presentation 958 - B0263. Novel Topical Inhibitors of the Epithelial Sodium Channel (ENaC) Promote Sustained Increases in Tear Volume William Thelin; M. Ross Johnson; John Ansede; Karl Donn; Dongfang Yu; Barbara Grubb; Driss Zoukhri; Richard C. Boucher; Jose L. Boyer View Presentation 959 - B0264. Variability of tear osmolarity in dry eye patients and controls Nicole M. Fuerst; Mina Massaro-Giordano; Bridgette E. McCabe; Ilaria Macchi; Maxwell Pistilli; Gui-Shuang Ying; Vatinee Y. Bunya View Presentation 960 - B0265. Symptom Burden of Patients with Dry Eye Disease: A Four Domain Analysis Joelle Hallak; Sarmad H. Jassim; Sandeep Jain View Presentation 961 - B0266. Frequency and Risk Factors Associated with Ocular Surface Disease in Patients Attending a Tertiary Care Ophthalmology Center in Mexico City Jaime D. Martinez; Nallely Ramos Betancourt; Anat Galor; Francisco Beltran; Jorge Ozorno-Zarate; Valeria Sánchez Huerta; Marco Antonio Torres Vera; Everardo Hernandez-Quintela View Presentation 962 - B0267. Blink and Extended Blinks in a Dry Eye Population Ashley M. LaFond; Patrick Johnston; John D. Rodriguez; Keith J. Lane; Endri Angjeli View Presentation 963 - B0268. Positive- and Negative Regulation of Transcripts Associated with Formation of Sjögren’s Lesions Austin K. Mircheff; Yanru Wang View Presentation 964 - B0269. Change of tear meniscus by CL wearing and therapeutic effect of eye drop for the change Hitoshi Watanabe; Yukiko Nagahara View Presentation 965 - B0270. Normative Values for the Tear Film of the Rabbit, Dog and Human Monica J. Motta; Peter C. Strom; Katarzyna Paschalis Trela; Andrea Rodrigues; Christopher J. Murphy View Presentation 966 - B0271. Intense Pulsed Light as a Treatment for Dry-eye Disease due to Meibomian Gland Dysfunction Rolando Toyos View Presentation 967 - B0272. Modeling Blink: Blink Rate or Interblink Interval? Patrick Johnston; Lisa Smith; John D. Rodriguez; Keith J. Lane; George W. Ousler; Richard Abelson View Presentation 968 - B0273. Zone A (ZA), Posterior Lid Margin Vascularization: An Early Sign of Ocular Surface Disease (OSD) Alexander Gan; Claudia M. Prospero Ponce; Andrew M. Quinn; Patricia Chevez-Barrios; Alice Z. Chuang; Richard W. Yee View Presentation 969 - B0274. Is there a relationship between ocular discomfort and circulating plasma levels of sex hormones? Preliminary findings Blanka Golebiowski; Ulrike Hampel; Noor Badarudin; Isabelle Jalbert; Michele C. Madigan; Fiona Stapleton View Presentation 970 - B0275. Correlation of Tear Meniscus Dimensions with Clinical Parameters of Ocular Surface Disease in Subgroups of Dry Eye Cynthia I. Tung; Andrew F. Perin; Koray Gumus; Stephen C. Pflugfelder View Presentation 971 - B0276. Upregulation of chemokine expression in experimental dry eye requires IL17A and IFN-γ but not T cells Terry G. Coursey; Stephen C. Pflugfelder; Cintia S. De Paiva View Presentation 972 - B0277. Differential effect of Th1- and Th2-type cytokines on rat conjunctival goblet cell function Laura Garcia-Posadas; Dayu Li; Robin R. Hodges; Marie A. Shatos; Yolanda Diebold; Darlene A. Dartt View Presentation 973 - B0278. Cytoprotective effect of lacritin on human corneal epithelial cells exposed to benzalkonium chloride Mary M. Feng; Julia Baryla; Hong Liu; Gordon W. Laurie; Robert L. McKown; Negin Ashki; Dinesh Bhayana; Cindy M. Hutnik View Presentation 974 - B0279. Functional characterization of the glucocorticoid receptor in the cornea Mahita Kadmiel; John A. Cidlowski View Presentation 975 - B0280. Reliability of Oculus Keratograph Meibomian Gland Assessments Stephanie Cox; Catherine Vuong; Lisa Jones-Jordan; Kelly K. Nichols; Jason J. Nichols View Presentation 976 - B0281. Matrix Metalloproteinases-8, -9 and Myeloperoxidase are Elevated in the Tears of Patients with Ocular Cicatricial Pemphigoid and Stevens-Johnson Syndrome Samer N. Arafat; Ana M. Suelves; Sandra J. Spurr-Michaud; James Chodosh; C. Stephen Foster; Claes H. Dohlman; Ilene K. Gipson View Presentation 977 - B0282. Autologous Serum Tears for Treatment of Dry Eye Syndrome in Graft Versus Host Disease Ryan J. Fante; Roni M. Shtein; Shahzad I. Mian; Munira Hussain View Presentation 978 - B0283. Autologous Serum Tears May Result in Subclinical Changes in Corneal Immunity: An In Vivo Confocal Microscopy Study Ahmad Kheirkhah; Shruti Aggarwal; Bernardo M. Cavalcanti; Deborah Witkin; Nadia Wong; Monique Trinidad; Candice Williams; Reza Dana; Pedram Hamrah View Presentation 140. Cell and Molecular Biology and Stem Cells Moderator(s): Yoko Ogawa (Keio Univ School of Medicine) 1:00 PM - 2:45 PM; Exhibit / Poster Hall 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM View Session Details 979 - B0284. Human Adipose-Derived Stem Cells Support the Growth of Limbal Stem/progenitor Cells Hua Mei; Martin N. Nakatsu; SHEYLA GONZALEZ; Elfren R. Baclagon; Sophie X. Deng View Presentation 980 - B0285. Periostin is associated with the properties of human corneal epithelial progenitor cells Yangluowa Qu; Cheng Li; Wei Li; Zuguo Liu View Presentation 981 - B0286. Differentiation Potential of Limbal Fibroblasts and Bone Marrow Mesenchymal Stem Cells to Corneal Epithelial Cells Kishore Reddy Katikireddy; Reza Dana; Ula V. Jurkunas View Presentation 982 - B0287. The effect of hypoxia on the growth of limbal stem cells Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 46 sur 222 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM Dean Hallam; Christin Henein; Satomi Miwa ; Sajjad Ahmad; Gabriele C. Saretzki View Presentation 983 - B0288. Downregulation of master transcription factor, Pax6, contributes to autoimmune-mediated keratinizing squamous metaplasia of the ocular surface via the aberrant activation of basal progenitor cells Ying-Ting Chen; Nancy A. McNamara View Presentation 984 - B0289. A Comparison Between Three Mouse Models of Corneal Limbal Stem Cell Deficiency Neda -. Afshar; Asadolah Movahedan; Ali R. Djalilian View Presentation 985 - B0290. Optimization of Ex Vivo Expansion of Limbal Epithelial Progenitors by Maintaining Native Niche Cells on Denuded Amniotic Membrane Megha A. Mahabole; Szu-Yu Chen; Scheffer C. Tseng View Presentation 986 - B0291. Self Assembly of the Limbal Epithelial Stem Cell Niche in Vitro Hideyuki Miyashita; Satoru Yoshida; Tetsuya Kawakita; Kazuo Tsubota; Shigeto Shimmura View Presentation 987 - B0292. Activation of the Hedgehog pathway is involved in the expansion of compound niches after corneal injury Ahdeah Pajoohesh-Ganji; Sonali Ghosh; Gauri Tadvalkar; Mary Ann Stepp View Presentation 988 - B0293. Unraveling the limbal epithelial stem cell niche: miRs-103/107 help maintain E-cadherin-mediated cell-cell contacts Julia V. Katsnelson; Jong Kook Park; Wending Yang; Han Peng; Robert M. Lavker View Presentation 989 - B0294. Comparison of Different Limbal Epithelial Stem Cell Isolation Methods to Improve the Epithelial Sheet Quality for Transplantation SHEYLA GONZALEZ; Martin N. Nakatsu; Hua Mei; Sophie X. Deng View Presentation 990 - B0295. Thermolysin treated AM preserves the BM providing superior expansion and preservation of cornea epithelial cells Aaron Yeung; Andrew Hopkinson; Harminder S. Dua View Presentation 991 - B0296. Characterization of Biomaterial free Cell Sheets Cultured from Human Oral Mucosal Epithelial Cells Mee Kum Kim; Joo Hee Lee; Ja Young Lee; Ah Young Koh; Yun Hee Kim; Won Ryang Wee; Saewha Jeon View Presentation 992 - B0297. Human adipose-derived stem cells promote wound healing of corneal epithelial cells in vitro Ladan Espandar; Tomas Blanco; Rose Mathew; Natalie A. Afshari; Bruce Bunnell; Daniel R. Saban View Presentation 993 - B0298. NGF inhibited apoptosis through phosphorylation of FOXO3a in human corneal epithelial cells Tingting Qian; Jiaxu Hong; JianJiang Xu View Presentation 994 - B0299. Transcription factor screening of limbal vs. corneal epithelium identifies distinct patterns for SOX-9 and peroxisome proliferator-activated receptor gamma (PPARG) Johannes Menzel-Severing; Matthias Zenkel; Friedrich E. Kruse; Ursula SchlotzerSchrehardt View Presentation 995 - B0300. Wnt promotes proliferation of corneal epithelial progenitor cells in xenofeeder free cultivation Kyung-Sun Na; Jeewon Mok; Jungmook Lyu; Choun-Ki Joo View Presentation 996 - B0301. Human limbal epithelium expanded in a complex medium or medium with human serum: a comparison of morphology and cytokeratin expression Meeta Pathak; Kristiane Haug; Aboulghassem Shahdadfar; Eli Gulliksen; Magnus Roeger; Liv Drolsum; Jon K. Slettedal; Bjorn Nicolaissen; Katerina Jirsova View Presentation 997 - B0302. Comparative gene expression analysis of human cornea limbal epithelial stem cells and differentiated corneal epithelium Goran Petrovski; Reka Albert; Zoltan Vereb; Morten C. Moe; Ole Kristoffer Olstad; Andras Berta; Laszlo Fesus View Presentation 998 - B0303. A NEW RAPID METHOD OF DENUDING HUMAN AMNIOTIC MEMBRANE FOR LIMBAL AND STEM CELL CULTURE Alexander V. Ljubimov; Dhruv Sareen; Loren Ornelas; Anais Sahabian; David M. Hemmati; Chantelle A. Ghiam; William J. Brunken; Yaron S. Rabinowitz; Clive Svendsen; Mehrnoosh Saghizadeh View Presentation 999 - B0304. Expansion of Human Corneal Epithelial Stem/Progenitor Cells in FeederFree Explant Cultures Sophie X. Deng; Martin N. Nakatsu; SHEYLA GONZALEZ; Hua Mei View Presentation 1000 - B0305. Sox9, a determinant of hair follicle stemness, identifies a subset of murine basal corneal epithelial cells expressing putative stem cell markers Rachel Sartaj; Aihong Liu; Elaine Fuchs; Mark Rosenblatt View Presentation 1001 - B0306. Limbal mesenchymal stromal cells (L-MSC) display immunosuppressive properties across donor and species boundaries Damien G. Harkin; Laura J. Bray; Celena Heazlewood; Kerry Atkinson View Presentation 1002 - B0307. EDC/NHS cross-linked amniotic membrane preferentially preserves corneal epithelial progenitor cells by activating Wnt/β catenin signaling David H. Ma; Hung-Chi Chen; Jui-Yang Lai; Kevin S. Ma; Lung-Kun Yeh; Unique Yang; Jessica Ma View Presentation 1003 - B0308. Immobilized HC-HA Preserves Limbal Niche Cell Phenotype to Prevent Limbal Epithelial Progenitor Cells from Differentiation Bo Han; Yingting Zhu; Suzhen Zhang; Scheffer C. Tseng View Presentation 1004 - B0309. Comparison of Human and Mouse Feeders, Xeno-free and Standard Media in Different Oxygen Tensions for Preservation of Human Limbal Progenitor Cells during Culture Kalliopi Stasi; Mina Massaro-Giordano; Jiayan Huang; John Gearhart View Presentation 1005 - B0310. Outcomes of Penetrating Keratoplasty after ex vivo Expanded Autologous Limbal Stem Cell Transplantation in Humans Oliver J. Baylis; Hardeep S. Mudhar; Majlinda Lako; Francisco C. Figueiredo View Presentation 1006 - B0311. Integrating human epithelial stem cells and keratocytes into a transparent, collagen based bioengineered cornea for disease modelling James W. Foster; Ana Maria Ionescu; Roanne R. Jones; Ricardo M. Gouveia; Che J. Connon View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 47 sur 222 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1007 - B0312. Evaluation of Corneal Stem/Progenitor Cells in leptin deficient mice Hiroki Ueno; Takaaki Hattori; Yuta Kumagai; Noboru Suzuki; Satoki Ueno View Presentation 1008 - B0313. Retinal Pigment Epithelial Cell Differentiation in Primary Human Limbal Neurosphere Cultures Samuel McLenachan; Dana Zhang; Fred K. Chen View Presentation 1009 - B0314. Transpalntation of umbilical mesenchymal stem cells cures the corneal defects of Mucopolysaccharidosis VII mice Vivien J. Coulson-Thomas; Bruce Caterson; Chia-Yang Liu; Winston W. Kao View Presentation 1010 - B0315. Dental Pulp: a Source of Stem Cells with Keratocyte Potential Martha L. Funderburgh; Fatima N. Syed-Picard; Charles S. Sfeir; James L. Funderburgh View Presentation 1011 - B0316. Corneal stroma derived MSCs maintain immunosuppression with wound healing capacity in vitro Zoltan Vereb; Reka Albert; Morten C. Moe; Laszlo Fesus; Eva Rajnavolgyi; Andras Berta; Goran Petrovski View Presentation 1012 - B0317. Engraftment and Survival of Human Umbilical Mesenchymal Stem Cells in the Mouse Cornea: An Immunofluorescent Computed Tomography Study Behdad Kavianpour; Geraint J. Parfitt; Hongshan Liu; Winston W. Kao; Donald J. Brown; Yilu Xie; Mikhail Geyfman; James V. Jester; Jennifer Simpson View Presentation 1013 - B0318. Influence of Secreted Ly6/uPAR-Related Protein-1 (Slurp1) on Corneal Stromal Fibroblast Proliferation, Interaction with the Extracellular Matrix, and Migration Shivalingappa K. Swamynathan; Sudha Swamynathan View Presentation 1014 - B0319. Stromal Cells derived from Amniotic Membrane are capable to reestablish corneal opacity Yonathan Garfias; Alejandro Navas; Jessica Nieves-Hernández; Gibran A. Estua; Rodrigo Bolaños-Jiménez View Presentation 1015 - B0320. Corneal endothelial cells derived from monkey iPS cells: a short term evaluation Shin Hatou; Satoru Yoshida; Kazunari Higa; Hideyuki Miyashita; Emi Inagaki; Erika Kimura; Ryuhei Hayashi; Kazuo Tsubota; Kohji Nishida; Shigeto Shimmura View Presentation 1016 - B0321. Bone Marrow-Derived Endothelial Progenitor Cells for Treatment of Corneal Endothelial Dysfunction Yao Fu; Chunyi Shao; Xianqun Fan View Presentation 1017 - B0322. Standardization of human corneal endothelial cell isolation and the use of denuded amniotic membrane as a scaffold for human corneal endothelial cells Kalpana Suresh; Tanvi Khanna; Alan M. Punnoose; Sarah Kuruvilla; Vishnu D. Narayanam; RAMYA RAVINDRAN; Varshini Varadaraj View Presentation 1018 - B0323. Isolation and characterization of p75NTR positive and high-proliferative corneal endothelial cells from the human corneal endothelium Susumu Hara; Ryuhei Hayashi; Tomofumi Kageyama; Motokazu Tsujikawa; Kohji Nishida View Presentation 1019 - B0324. Spatial transcriptome of human cornea using next generation sequencer Suguru Nakagawa; Tomohiko Usui; Hiroki Ueda; Genta Nagae; Shogo Yamamoto; Satoru Yamagami; Hiroyuki Aburatani; Shiro Amano View Presentation 1020 - B0325. Human cornea proteome: Identification and quantitation of the proteins of the three main layers including epithelium, stroma and endothelium Thomas Dyrlund; Ebbe Toftgaard Poulsen; Carsten Scavenius; Camilla Lund Nikolajsen; Ida B. Thøgersen; Henrik Vorum; Jan J. Enghild View Presentation 1021 - B0326. Immunocytochemical analysis after treatment with osmoprotective and oil containing lubricants in dry eye and refractive surgery patients Renata R. Loureiro; Rossen M. Hazarbassanov; Joyce L. Covre; Priscila C. Cristovam; Jeison d. Barros; Jose A. Gomes View Presentation 1022 - B0327. The Regeneration Potential of Mouse Lacrimal Gland Following Duct Ligation Procedure Ying Liu; Tetsuya Kawakita; Machiko Sugiyama; Masatoshi Hirayama; Motoko Kawashima; Yoko Ogawa; Masataka Ito; Shigeto Shimmura; Kazuo Tsubota View Presentation 1023 - B0328. Prosthetic Replacement for the Ocular Surface Environment (PROSE) Alters The Lacrimal Functional Unit Yvonne Wang; Ryan M. St Clair; Michelle N. Lee; Kimberly C. Sippel; Jessica Ciralsky; Priyanka Sood; Ana G. Alzaga Fernandez; Christopher E. Starr; Mark Rosenblatt View Presentation 141. Retinal Prosthesis II Moderator(s): Motohiro Kamei (Osaka Univ Grad School of Medicine) and Eberhart Zrenner (Centre for Ophthalmology) 1:00 PM - 2:45 PM; Exhibit / Poster Hall 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM View Session Details 1024 - C0001. Electrically elicited visually evoked potentials (eVEPs) in Argus® II prosthesis wearers H Christiaan Stronks; Gislin Dagnelie; Michael P. Barry View Presentation 1025 - C0002. Intra-Retinal Electrical Stimulation: Comparison to Epi- and Sub-Retinal Approaches David Boinagrov; Susanne Pangratz-Fuehrer; Keith Mathieson; Georges A. Goetz; Ludwig Galambos; Daniel V. Palanker View Presentation 1026 - C0003. Comparison of Electrically Evoked Retinal Ganglion Cell (RGC) Responses by Square Pulse and Triangle Pulse in rd1 mice Yongsook Goo; Kun No Ahn; Seol A Jae; Joo Yun Kim View Presentation 1027 - C0004. The Feasibility of Explanting a Suprachoroidal Electrode Array in a Feline Model Ronald T. Leung; David A. Nayagam; Richard A. Williams; Penelope J. Allen; Cesar M. Salinas-La Rosa; Chi D. Luu; Lauren N. Ayton; Meri Basa; Robert K. Shepherd; Chris E. Williams View Presentation 1028 - C0005. Development of a surgical procedure for implanting a wide view electrode array in the suprachoroidal space Jonathan Yeoh; Alexia Saunders; David A. Nayagam; Chris E. Williams; Mark McCombe; Burns Owen; Joel Villalobos; Michelle McPhedran; Robert Briggs; Penelope J. Allen View Presentation 1029 - C0006. In Vivo Electrical Stimulation of a Retinal Prosthesis Containing Conductive Diamond Electrodes Mohit N. Shivdasani; David J. Garrett; David A. Nayagam; Joel Villalobos; Penelope J. Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 48 sur 222 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM Allen; Alexia Saunders; Michelle McPhedran; Ceara McGowan; Hamish Meffin; Robert K. Shepherd View Presentation 1030 - C0007. A Suprachoroidal Retinal Prosthesis with a Flexible Lead is Reliable for Patient Testing Joel Villalobos; Penelope J. Allen; Chi D. Luu; Lauren N. Ayton; Jonathan Yeoh; David A. Nayagam; Nicholas L. Opie; Mohit N. Shivdasani; Robert K. Shepherd; Chris E. Williams View Presentation 1031 - C0008. Bionic Vision Australia - Implantation of a suprachoroidal retinal prosthesis- results for the first participants Penelope J. Allen; Jonathan Yeoh; Mark McCombe; Wilson J. Heriot; Chi D. Luu; Lauren N. Ayton; David A. Nayagam; Robert K. Shepherd; Peter J. Blamey; Robyn H. Guymer View Presentation 1032 - C0009. Operation and Performance of Eye-conformable Retinal Prosthesis using Liquid Crystal Polymer Joonsoo Jeong; Seung Woo Lee; Kyou sik Min; Soowon Shin; So Hyun Bae; Tae Wan Kim; Bum-Joo Cho; Jong-Mo Seo; Hum Chung; Sung June Kim View Presentation 1033 - C0010. A bottom-up visual saliency-based image processing strategy for object recognition under simulated prosthetic vision Xinyu Chai; Yanyu Lu; Weizhen Fu; Yao Chen; Chuanqing Zhou; Jing Wang View Presentation 1034 - C0011. Immunohistochemical and electrophysiological analysis of rat retinas after subretinal implantation of photovoltaic arrays Jacob G. Light; James W. Fransen; Alice Adkins; Gobinda Pangeni; James Loudin; Keith Mathieson; Daniel V. Palanker; Maureen A. McCall; Machelle T. Pardue View Presentation 1035 - C0012. Physiological Response of RD Mouse Retinal Ganglion Cells to Electrical Stimulation Alice Cho; Alapakkam P. Sampath; Mark S. Humayun; James D. Weiland View Presentation 1036 - C0013. Re-alignment and explantation of subretinal prostheses: surgical aspects and proteomic analyses Florian Gekeler; Helmut G. Sachs; Veronique Kitiratschky; Katarina Stingl; Udo Greppmaier; Eberhart Zrenner; Karl-Ulrich Bartz-Schmidt; Marius Ueffing; Sascha Dammeier View Presentation 1037 - C0014. Long-term Reliability of Argus® II Retinal Implants David Zhou; Alexander Istomin; Amy Hines; Alina Agazaryan; Charles A. Byers; James Little; Brian V. Mech; Robert J. Greenberg View Presentation 1038 - C0015. Morphological comparisons of flat and 3-dimensional subretinal photovoltaic arrays in rat and pig models of retinitis pigmentosa Alice Adkins; Wei Wang; Henry J. Kaplan; Douglas Emery; Juan P. Fernandez de Castro; Sang-Joon Lee; Philip Huie; Daniel V. Palanker; Maureen A. McCall; Machelle T. Pardue View Presentation 1039 - C0016. Combining holographic stimulation with cellular resolution imaging in the rodent eye Shy Shoham; Adi Schejter; Limor Tsur; Inna Reutsky-Gefen; Nairouz Farah View Presentation 1040 - C0017. Argus® II Retinal Prosthesis System safety profile in post-market patients Robert J. Greenberg; Peter Walter; Albert J. Augustin; Bernd Kirchhof; Lyndon daCruz; Hannah Schimitzek; Gernot Roessler; Stanislao Rizzo View Presentation 1041 - C0018. Simulating current focusing and steering in penetrative optic nerve stimulation: a computational model Qiushi Ren; Menghui Li; Yan Yan; Liming Li View Presentation 1042 - C0019. Retinal Prostheses: Functional Use of Monocular Depth Perception in the Low Resolution Limit Noelle R. Stiles; Ben P. McIntosh; Armand R. Tanguay; Mark S. Humayun View Presentation 1043 - C0020. Relative efficiency of voltage vs. current pulses for retinal stimulation Navya S. Davuluri; Mark S. Humayun; James D. Weiland View Presentation 1044 - C0021. Psychophysics of a suprachoroidal retinal prosthesis Peter J. Blamey; Nicholas C. Sinclair; Kyle Slater; Hugh J. McDermott; Thushara Perera; Peter N. Dimitrov; Mary Varsamidis; Lauren N. Ayton; Robyn H. Guymer; Chi D. Luu View Presentation 1045 - C0022. Determination of Electrode Proximity to the Retinal Surface from the Stimulus Pulse Waveform Joseph Majdi; Saugandhika Minnikanti; Anant Agrawal; Nathalia Peixoto; Ethan D. Cohen View Presentation 1046 - C0023. Evaluation of safety of porous surface electrodes for STS Retinal prosthesis Hiroyuki Kanda; Takeshi Morimoto; Yasuo Terasawa; Yukari Nakano; Kohji Nishida; Takashi Fujikado View Presentation 1047 - C0024. A monolithic diamond microelectrode array fabricated for a high acuity retinal prosthesis Kumaravelu Ganesan; David J. Garrett; Mohit N. Shivdasani; David A. Nayagam; Joel Villalobos; Hamish Meffin; Kate E. Fox; Samantha G. Lichter; Robert K. Shepherd View Presentation 1048 - C0025. New Advancements to High-Density Packaging Technology for the Boston Retinal Prosthesis Douglas B. Shire; Thomas Salzer; William K. Jones; Ali Karbasi; Oscar D. Mendoza; Shawn K. Kelly; John L. Wyatt; Joseph F. Rizzo View Presentation 1049 - C0026. Evaluating Lanczos2 Image Filtering for Visual Acuity In Simulated Prosthetic Vision Paulette Lieby; Adele F. Scott; Nick M. Barnes; Ashley Stacey; Lauren N. Ayton; Janine G. Walker View Presentation 1050 - C0027. Responses evoked by monopolar and bipolar photovoltaic arrays in the S334ter-3 rat model of retinitis pigmentosa James W. Fransen; Gobinda Pangeni; Benjamin M. James; James Loudin; Keith Mathieson; Theodore I. Kamins; James Harris; Daniel V. Palanker; Machelle T. Pardue; Maureen A. McCall View Presentation 1051 - C0028. MRI Brain Scan in Argus II Retinal Prosthesis Patients Yvonne H. Luo; Indran Davagnanam ; Lyndon daCruz View Presentation 1052 - C0029. Developing a Rehabilitation Curriculum for Argus® II System Users Jessy D. Dorn; Duane Geruschat; Fatima Anaflous; Robert J. Greenberg View Presentation 1053 - C0030. Chronic Electrical Stimulation Of The Retina Via Suprachoroidal Electrodes Is Safe Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 49 sur 222 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM David A. Nayagam; Richard A. Williams; Mohit N. Shivdasani; Cesar M. Salinas-La Rosa; Penelope J. Allen; Ceara McGowan; Chi D. Luu; Lauren N. Ayton; Chris E. Williams; Robert K. Shepherd View Presentation 1054 - C0031. In vivo chronological observation of electrochemical properties of porous electrodes with chronic suprachoroidal-transretinal stimulation Yasuo Terasawa; Hiroyuki Tashiro; Yukari Nakano; Koji Osawa; Motoki Ozawa View Presentation 1055 - C0032. Comparison of Ankyrin-G Labeling of Axon Initial Segments on Ganglion Cells in Normal and Degenerate Rat Retina Steven T. Walston; Eun-Jin Lee; Mark S. Humayun; James D. Weiland View Presentation 1056 - C0033. An Optimal Power Coil Configuration to Minimize Surgical Cut for Intraocular Retinal Prostheses Yu Zhao; Charles DeBoer; Mandheerej S. Nandra; James D. Weiland; Mark S. Humayun; Yu-Chong Tai View Presentation 1057 - C0034. Visual Prosthesis Simulation: Effects of Foveation on Visual Search Ben P. McIntosh; Noelle R. Stiles; Mark S. Humayun; Armand R. Tanguay View Presentation 1058 - C0035. Decrease in Electrode-Retina Distance over Time and its Effect on Electrical Impedances in a Suprachoroidal Retinal Prosthesis Lauren N. Ayton; Nicholas C. Sinclair; Peter J. Blamey; Thushara Perera; David A. Nayagam; Peter N. Dimitrov; Penelope J. Allen; Mary Varsamidis; Robyn H. Guymer; Chi D. Luu View Presentation 1059 - C0036. Analysis of retinal and cortical response to electrical stimulation by Subretinal implant in rodent model Frederic Matonti; Sebastien Roux; Virginie Donnadieu; Henri Lorach; Olivier Marre; Serge A. Picaud; Frederic Chavane View Presentation 1060 - C0037. Spatial resolution of the Penetrative Optic Nerve Visual Prosthesis estimated by epidural cortical recording Yao Chen; Yiliang Lu; Yan Yan; Liming Li; Xinyu Chai View Presentation 1061 - C0038. Development of large multielectrode arrays for epiretinal stimulation – feasibility of implantation procedures Gernot Roessler; Thomas Laube; Florian Waschkowski; Anne C. Rieck; Claudia Brockmann; Wilfried Mokwa; Peter Walter View Presentation 1062 - C0039. In vivo evaluation of the liquid crystal polymer-based retinal prosthesis by optical coherence tomography Hum Chung; Bum-Joo Cho; Hee Sun Park; So Hyun Bae; Tae Wan Kim; Jong-Mo Seo; Hyeong Gon Yu; Joonsoo Jeong; Soowon Shin; Sung June Kim View Presentation 1063 - C0040. Optimal electrode conditions for surprachoroidal-transretinal stimulation system to elicit electrically-evoked potentials Kentaro Nishida; Hirokazu Sakaguchi; Takashi Fujikado; Motohiro Kamei; Kohji Nishida View Presentation 1064 - C0041. Reducing the Number of Stimulators and Electrical Tracks in HighResolution Visual Prostheses Milan Djilas; Ryad Benosman; Philippe Bergonzo; Christoph Posch; Jose A. Sahel; Serge A. Picaud View Presentation 1065 - C0042. Design of the electrode and the system package for the retina prosthesis based on liquid crystal polymer Jong-Mo Seo; Bum-Joo Cho; So Hyun Bae; Tae Wan Kim; Hyo Joo Shin; Joonsoo Jeong; Soowon Shin; Dong-il "Dan" Cho; Sung June Kim; Hum Chung View Presentation 1066 - C0043. Suprachoroidal Electrical Stimulation by an MEMS-based Flexible Microelectrode array Xiaohong Sui; Yan Yan; Jingjing Sun; Liming Li; Qiushi Ren; Xinyu Chai View Presentation 1067 - C0044. A Center-Surround-Selectable, High-Acuity, Large-Field-of-View, Flexible Retinal Prosthesis Long-Sheng Fan; Chia-He Chung; Frank Yang; Eunice Liu; Jasmine Lin; Zung-Hua Yang; Grace Teng; Chang-Hao Yang; Kea-Tiong Tang View Presentation 1068 - C0045. Design of a Compact Wide-Field-of-View Camera for Retinal Prostheses Furkan E. Sahin; Ben P. McIntosh; Patrick J. Nasiatka; James D. Weiland; Mark S. Humayun; Armand R. Tanguay View Presentation 142. Drug Delivery I Moderator(s): Tao Lowe (Univ of Tennessee Health Science Ctr) and Uday Kompella (University of Colorado Denver) 1:00 PM - 2:45 PM; Exhibit / Poster Hall 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM View Session Details 1069 - C0046. Bioresorbable materials for ophthalmic devices Ananth Iyer; Rick Gallagher View Presentation 1070 - C0047. PLGA capsulated porous silicon particles for sustained intravitreal delivery of daunorubicin Kaihui Nan; Feiyan Ma; Huiyuan Hou; William R. Freeman; Michael J. Sailor; Lingyun Cheng View Presentation 1071 - C0048. Mechanism of ultrasound-mediated transscleral delivery: temporary alteration of scleral structure increases permeability of macromolecules Ying Chau; Wai-Leung Suen; Jun Jiang; Yan Zeng; Jianan Qu View Presentation 1072 - C0049. An aqueous clear rapamycin topical drop for retinal delivery Kishore Cholkar; Sriram Gunda; Ravinder Earla; Ashim K. Mitra View Presentation 1073 - C0050. Cell-Encapsulated Device for Intraocular Delivery of Glial-Cell Derived Neurotrophic Factor (GDNF) Francisca SY Wong; Calvin CH Wong; Barbara P. Chan; Amy C. Lo View Presentation 1074 - C0051. Long-lasting eye drop delivery platform for targeted ocular delivery applications Frank Gu; Shengyan Liu; Lyndon W. Jones View Presentation 1075 - C0052. Hyaluronic acid based tablet for slow release of ilomastat in glaucoma filtration surgery Abeer Mohamed Ahmed; Alastair Lockwood; Steve Brocchini; Peng T. Khaw View Presentation 1076 - C0053. NOVEL AQUEOUS NANOMICELLAR FORMULATIONS CONTAINING FLUOCINOLONE ACETONIDE FOR THE TREATMENT OF POSTERIOR UVEITIS Sujay Shah; Asha Patel; Sulabh Patel; Dhananjay Pal; Ashim K. Mitra View Presentation 1077 - C0054. Topically Administered Mouse IgG1 Accumulates In the Rat Optic Nerve Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 50 sur 222 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM And Retina Stacy Hu; Steven B. Koevary View Presentation 1078 - C0055. A Pilot Safety Assessment of a Topical Ocular Device (TODDD™) Intended for Sustained Drug Delivery Charles D. Leahy; Rodney Gutner; Whittney Varney; Jack Rulander; Stephen Johnston; Francis S. Lai; Kathryn S. Crawford; Roger Albright; Jeanne Y. Ellis; Edward J. Ellis View Presentation 1079 - C0056. Precisely Engineered Biodegradable Intraocular Implants for the Sustained Release of Dexamethasone Andres Garcia; Janet Tully; Benjamin Maynor; Benjamin Yerxa View Presentation 1080 - C0057. Intraocular pharmacokinetics of bevacizumab and ranibizumab in vitrectomized versus non-vitrectomized rabbit eyes Jeeyun Ahn; Sunyoung Park; Hyuncheol Kim; Ji Hyun Park; Ji Yeon Park; Duck Jin Hwang; Seong Joon Ahn; Yong-Kyu Kim; Kyu Hyung Park; Se Joon Woo View Presentation 1081 - C0058. Key considerations for choice of syringes for delivery of intravitreal therapies in enhancing safety and efficacy of therapies injected in the eye GAUTAM SHETTY View Presentation 1082 - C0059. Freeze Drying to Develop a Bevacizumab-based Tablet for Ocular Implantation Garima Sharma; Ashkan Khalili; Sahar Awwad; Kiran Malik; Paul Matejtschuk; Simon Gaisford; Steve Brocchini; Peng T. Khaw View Presentation 1083 - C0060. Efficiency of a new pre-loaded, microincision insertion system for a 1piece hydrophobic-acrylic intraocular lens Scott Evans; Don R. Nixon View Presentation 1084 - C0061. Correlation between release of rapamycin from Porous Silicon (pSi) and the color shifting of pSi monitored by a digital camera: a prototype of non-invasive remote monitoring system for intravitreal drug release Lingyun Cheng; Huiyuan Hou; Alejandra Nieto; Gordon Miskelly; Dirk-Uwe G. Bartsch; William Freeman; Michael J. Sailor View Presentation 1085 - C0062. Porous Silicon Microparticle Formulation as an Intravitreal Delivery System for Rapamycin Alejandra Nieto; Huiyuan Hou; Michael J. Sailor; William Freeman; Lingyun Cheng View Presentation 1086 - C0063. Uptake and Release of ciprofloxacin and dexamethasone from commercial contact lens materials Alex Hui; Lyndon W. Jones View Presentation 1087 - C0064. Enhanced Topical Delivery of a Small Molecule Receptor Tyrosine Kinase Inhibitor (RTKi) via Mucosal-Penetrating Particle Technology Lisa Schopf; Elizabeth Enlow Enlow; Alexey Popov; James L. Bourassa; Hongming Chen View Presentation 1088 - C0065. Proteins in solid dosage form (implantable tablets) for ocular delivery Ashkan Khalili; Garima Sharma; Alastair Lockwood; Sahar Awwad; Steve Brocchini; Peng T. Khaw View Presentation 1089 - C0066. Pharmacokinetics Demonstrating Sustained Dexamethasone Delivery from a Punctum Plug in a Canine Model Ankita Desai; Charles D. Blizzard; Michael Bassett; Amar S. Sawhney; Peter Jarrett; Michael McGrath; Arthur Driscoll View Presentation 1090 - C0067. Use of galectin-3 fusions to extend the surface residence time of proteins topically applied to the eye Thomas Barnes; Joseph T. Kovalchin; Allyson Masci; Michael Schmidt; Pamela Pegman; Patricia A. Lowden; Christian Dombrowski View Presentation 1091 - C0068. Application of PRINT Microparticle and Nanoparticle Technology Toward Preparation of Ophthalmic Suspension Formulations with Improved Tolerability and Efficacy Benjamin Maynor; Andres Garcia; Janet Tully; Benjamin Yerxa View Presentation 1092 - C0069. Evaluation of drug delivery and biocompatibility of biodegradable microfilms in the anterior segment of the rat model Yan Peng; Yu-Chi Liu; Nyein Chan Lwin; Subbu S Venkatraman; Tina Wong; Jodhbir S. Mehta View Presentation 1093 - C0070. Safety of DuraSite vehicle as part of a topical treatment in cataract surgery patients Judith Hutcheson; Lyle M. Bowman; Kamran Hosseini View Presentation 1094 - C0071. Neuroprotective effect on the retinal ganglion cells by brimonidine loaded HSA nanoparticles in the acute optic nerve crush model Hyuncheol Kim; Hyungwon Moon; Kyoung Nam Kim; Yu Jeong Kim; Jin Wook Jeoung; Ki Ho Park View Presentation 1095 - C0072. Sustained release of ovalbumin and IgG from hydrogel depots as surrogate proteins for intravitreal injection Rami Elhayek; Rami Elhayek; Peter Jarrett; Amar S. Sawhney; Sarah Guedez View Presentation 1096 - C0073. VITAMIN E INCREASES THE BIOACTIVITY IN RETINAL CELLS OF MICROENCAPSULATED GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR Irene Bravo-Osuna; Patricia Checa-Casalengua; Caihui Jiang; Budd A. Tucker; Irene T. Molina-Martínez; Michael J. Young; Rocio Herrero-Vanrell View Presentation 1097 - C0074. Pharmacokinetic Evaluation of Sustained Delivery Moxifloxacin Punctum Plugs Michael Bassett; Charles D. Blizzard; Peter K. Jarrett; Arthur Driscoll; Ankita Desai; Deepa Mulani; Michael McGrath; Amar S. Sawhney View Presentation 1098 - C0075. Distribution And Clearance Of Microparticles And Nanoparticles In The Suprachoroidal Space After Injection Using Hollow Microneedles In Rabbits Yoo C. Kim; Mark Prausnitz; Henry F. Edelhauser View Presentation 1099 - C0076. Examination of in vitro release profiles of bromfenac, diclofenac and nepafenac as drug candidates for sustained release NSAID punctum plug Peter K. Jarrett; Rami Elhayek; Sarah Guedez; Amar S. Sawhney View Presentation 143. Endophthalmitis Poster Moderator(s): Usha Chakravarthy (Queens University of Belfast) 1:00 PM - 2:45 PM; Exhibit / Poster Hall 1:00 PM - 2:45 PM View Session Details 1100 - C0077. Crystal-induced endophthalmitis after intravitreal triamcinolone Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 51 sur 222 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM Hiroki Otsuka; Hiroki Kawano; Shozo Sonoda; Taiji Sakamoto View Presentation 1101 - C0078. Clinical Features and Treatment Outcomes of Endogenous Endophthalmitis Nicole H. Siegel; Achal J. Patel; Deeba Husain View Presentation 1102 - C0079. The Incidence of Curvularia Keratitis and A Case Series of Curvularia Endophthalmitis Ashvini Reddy; Aleksandra V. Rachitskaya; Darlene Miller; Harry W. Flynn; William E. Smiddy; Wilfredo C. Lara; Thomas A. Albini View Presentation 1103 - C0080. Differentiation of culture positive endophthalmitis from non-infectious endophthalmitis following intravitreal anti-VEGF injections Kamal Kishore; Bharti Kashyap; Anthony S. Ekong View Presentation 1104 - C0081. The Incidence of Noninfectious Intraocular Inflammation after Intravitreal Aflibercept Injection Kunjal K. Modi; Daniel B. Roth; Howard F. Fine; Harold M. Wheatley; Jonathan L. Prenner; Stuart N. Green; David L. Yarian View Presentation 1105 - C0082. Endophthalmitis following intravitreal injection: spectrum of causative organisms and antimicrobial susceptibility Grace Peng; Paulo J. Bispo; Maria Cecilia Z. Yu; Ana Luisa Hofling-Lima View Presentation 1106 - C0083. Torque Teno Virus Associated with Endophthalmitis Aaron Y. Lee; Lakshmi Akileswaran; Michael D. Tibbetts; Sunir J. Garg; Russell N. Van Gelder View Presentation 1107 - C0084. Intraocular Penetration of Systemic Antibiotics Following Scleral or Corneal Penetrating Injury Shareef Ahmed; Himanshu Aggarwal; Oscar C. Kuruvilla; David S. Chin Yee; Yue Li; Paul A. Edwards; Xiaoxi Qiao; Hua Gao View Presentation 1108 - C0085. Incidence of Endophthalmitis After Wearing Surgical Masks During Intravitreal Injections Erin Lessner; Rebecca Lessner View Presentation 1109 - C0086. Endophthalmitis Caused by Streptococcal Species Kathleen D. Weiss; Ajay E. Kuriyan; Harry W. Flynn; Darlene Miller View Presentation 1110 - C0087. Outbreak of Fusarium endophthalmitis following Brilliant Blue G (BBG) dye-assisted vitrectomy procedures Michael Davis; Kristie Lin; Tom Chang; Mike Samuel; Rizwan Bhatti; Steven Friedlander; Nishita Patel; Pravin U. Dugel View Presentation 1111 - C0088. Anatomical and visual outcome after pars plana vitrectomy in acute postcataract endophthalmitis Thierry ZHOU; Aurelie Combey; Nelly Campolmi; Catherine Creuzot-Garcher; Frederic Rouberol; Pierre-Loic Cornut; Karine Palombi; Gilles Thuret; Christophe Chiquet View Presentation 1112 - C0089. A 10-Year Study of Membrane Filter System versus Blood Culture Bottles in Culturing Vitrectomy Cassette Vitreous in Infectious Endophthalmitis Aleksandra V. Rachitskaya; Harry W. Flynn; James Wong; Ajay E. Kuriyan; Darlene Miller View Presentation 1113 - C0090. The role of antibiotic prophylaxis to prevent post-injection endophthalmitis Philip P. Storey; Michael Dollin; John D. Pitcher; Joseph Vojtko; Natalie Fang-Yen; James Vander; Jason Hsu; Sunir J. Garg View Presentation 1114 - C0091. Incidence of Endophthalmitis after Anti-VEGF Injections and use of AntiMicrobials in the Comparison of AMD Treatments Trials (CATT) Colin A. McCannel; Travis Meredith; Ellen Peskin; Maureen G. Maguire; Charles C. Barr; Beranrd Doft; Jonathan L. Prenner View Presentation 1115 - C0092. Endogenous Endophthalmitis associated with intravenous drug abuse Shriji Patel; Ronald J. Rescigno; Marco A. Zarbin; Neelakshi Bhagat View Presentation 1116 - C0093. Acute endophthalmitis post-intravitreal bevacizumab injections wearing surgical masks Mohamed Haji; Erika Massicotte; Flavio A. Rezende View Presentation 1117 - C0094. Crying wolf or a real problem : poisson distribution statistics for rare events applied to endophthalmitis Sankha Amarakoon; Jose P. Martinez-Ciriano ; René Wubbels; L I. van den Born; Suzanne Yzer; Mirjam E. Van Velthoven; Tom Missotten View Presentation 1118 - C0095. Meta-Analysis of Infectious Endophthalmitis After Intravitreal Injection of Anti-Vascular Endothelial Growth Factor Agents John Fileta; Ingrid U. Scott; Harry W. Flynn View Presentation 1119 - C0096. Pediatric Infectious Endophthalmitis: A Case Series Bryan P. Jones; Lisa Athwal; Marco A. Zarbin; Paul D. Langer; Neelakshi Bhagat View Presentation 1120 - C0097. Characterization of Prognostic Factors of Endophthalmitis Nausheen Abbas; John Huang View Presentation 1121 - C0098. Endophthalmitis after open globe trauma Sebastian P. Lesniak; Alain M. Bauza; Marco A. Zarbin; Paul D. Langer; Neelakshi Bhagat View Presentation 1122 - C0099. Conjunctival Flora Antibiotic Resistance Patterns After Serial Intravitreal Injections without Post-Injection Topical Antibiotics Adam T. Gerstenblith; Sunir J. Garg; James Vander; Jason Hsu View Presentation 1123 - C0100. Fungal Endophthalmitis Onset Due To Intravitreal Triamcinilone Contaminated by a Compounding Pharmacy Kent W. Small View Presentation 1124 - C0101. Endophthalmitis after glaucoma filtering procedure and Glaucoma drainage implants, incidence, outcomes, and management: tertiary care experiance Riyadh Saba Alreshaid; J. Fernando Arevalo; Sulaiman M. Al Sulaiman; jluwi almasaud; Nasira Asghar; Deepak P. Edward View Presentation 1125 - C0102. The Effects of Repeat Punctures and Draws of Bevacizumab on Needle Tip Cultures During Staged Clinical Setting for Intravitreal Drug Delivery Victor A. Neamtu; Surbhi Bansal; Boleslav Kotlyar; Hoon Jung View Presentation 1126 - C0103. Endogenous Endophthalmitis caused by Molds: Risk Factors, Management Strategies, and Visual Acuity Outcomes Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 52 sur 222 Jayanth Sridhar; Harry W. Flynn; Darlene Miller; Thomas A. Albini View Presentation 144. Diabetic Retinopathy, Vein Occlusion, Retinal Ischemia View Session Details Moderator(s): William Freeman (UCSD Jacobs Retina Center) and Ron Adelman (Yale Univ Sch of Medicine) 1:00 PM - 2:45 PM; Exhibit / Poster Hall 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM Withdrawn 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1127 - D0031. Impact of Anti-VEGF Therapy on Visual Impairment from Macular Edema Due to Branch Retinal Vein Occlusion Mariana S. Lopes; Connie J. Chen; Voraporn Chaikitmongkol; Yulia Wolfson; Susan B. Bressler; Neil M. Bressler View Presentation 1128 - D0032. Correlation of the Aqueous and Vitreous Proteomes in Diabetic Eye Disease Nour Maya N. Haddad; Jennifer K. Sun; Michael Molla; Paul G. Arrigg; Sabera T. Shah; Deborah K. Schlossman; Timothy J. Murtha; Edward P. Feener; Lloyd P. Aiello View Presentation 1129 - D0033. Retrospective Study of Anti-Vascular Endothelial Growth Factor Therapy in the Treatment of Branch Retinal Vein Occlusion and Predictive Factors for Visual Outcome Peng Lei View Presentation 1130 - D0034. VEGF and TNF Interact to Induce Retinal Edema in an Atypical PKC Dependent Manner Cheng-mao Lin; Paul M. Titchenell; Arivalagan Muthusamy; David A. Antonetti View Presentation 1131 - D0035. The Role of Apelin in the Retina of Diabetic Rats Yanrong Jiang; Qiang Lu; Jing Feng View Presentation 1132 - D0036. MiR-200b downregulates Oxidation resistance 1 (Oxr1) in diabetic retinopathy of a type 1 diabetic animal model Qian Chen; Anne Murray; Yusuke Takahashi; Kelu Zhou; Kyoungmin Park; Jian-Xing Ma View Presentation 1133 - D0037. Choroidal Thickness and Retinal Thickness in Cystoid Macular Edema on Enhanced Depth Imaging Optical Coherence Tomography Ella H. Leung; Patricia Garcia; Richard B. Rosen View Presentation 1134 - D0038. The role of sphingolipid metabolism in diabetes-induced retinal VEGF secretion Harshini Chakravarthy; Todd Lydic; Peter Jajou; Svetlana N. Bozack; Matthew S. Faber; Walter J. Esselman; Susanne Mohr; Julia V. Busik View Presentation 1135 - D0039. Quantitative Comparison of Choroidal Hyperpermeability Change with Low-fluence Photodynamic Therapy and Intravitreal Ranibizumab for Chronic Central Serous Chorioretinopathy Jeong-Ah Kim; Joo Young Shin; So Hyun Bae; Jeeyun Ahn; Hum Chung; Jang won Heo View Presentation 1136 - D0040. Central serous chorioretinopathy associated with homeopathic adrenal medication Derek Huang; Robert Millay; Brian Kim View Presentation 1137 - D0041. Plasma Kallikrein Deficiency is protective against diabetes induced retinal vascular dysfunction Allen Clermont; Qunfang Zhou; Takeshi Kita; Jia Liu; Lloyd P. Aiello; Edward P. Feener View Presentation 1138 - D0042. Inflammatory Cytokine levels of Aqueous Humour in Central Serous Chorioretinopathy Sung Jae Yang; Kyung-A Kim; Sea Woon Sohn; Sang Hoon Jung View Presentation 1139 - D0043. β-Amyloid deposition in human glaucomatous retinae revealed by proteomic and immunohistochemical analyses Nadine von Thun und Hohenstein-Blaul; Oliver W. Gramlich; Maarten B. Ruitenberg; Andreas Gravius; Franz H. Grus View Presentation 1140 - D0044. Activation of Prolyl Hydroxylase-2 Prevented High Glucose-Induced Endothelial Barrier Dysfunction Xiaoling Liang; Liqing Wei; Gang Sun; Cheng Yang; Huanjiao Zhou; Lu Yang; Peirong Lin View Presentation 1141 - D0045. Investigation of Multiple Proinflammatory Cytokines in the Aqueous Humor in Eyes with Secondary Glaucoma Toshihiro Inoue; Hidenobu Tanihara View Presentation 1142 - D0046. Distinct protein complex formation evokes insolubility of OPTN and mislocalization in iPSC-derived neural cells from E50K-POAG patients Yuriko Minegishi; Takeshi Iwata View Presentation 1143 - D0047. Role of Dopamine Deficiency in Visual Dysfunction in Early-stage Diabetic Retinopathy Moe H. Aung; Moon K. Han; Han na Park; Jane Abey; Peter M. Thule; P M. Iuvone; Machelle T. Pardue View Presentation 1144 - D0048. Sequential in-office Vitreous aspirations demonstrate that up-regulation of Matrix Metalloproteinases may regulate angiogenesis in Diabetic Retinopathy Joshua C. Hines; Stephanie M. Ecker; Bert M. Glaser View Presentation 1145 - D0049. Can Adiponectin be a Therapeutic Target for Proliferative Diabetic Retinopathy? sulochana natarajan; Subbulakshmi Chidambaram; Vidhya Srinivasan; Karthikka Palanisamy; Pukhraj Rishi; Radhakrishnan Selvi View Presentation 1146 - D0050. Ultra-widefield fluorescein angiography in patients with retinal vein occlusion Suzuki Norihiro; Shuichiro Hirahara; Ikuko Shimada; Satoshi Ota; Munenori Yoshida; Yuichiro Ogura View Presentation 1147 - D0051. Peroxiredoxin Crosstalk With Toll-like Receptor 4: A Novel Mechanism Implicated In The Pathogenesis Of Diabetic Retinopathy Folami Lamoke; Sean Shaw; AnnaLisa Montemari; Wan Jin Jahng; Manuela Bartoli View Presentation 1148 - D0052. Methylglyoxal Activates Chronic ER Stress Mediated Epigenetic Loss of Nrf2/Keap1 Gene Regulation in Diabetic Cataractous Lenses Palsamy Periyasamy; Masahiko Ayaki; Keshore R. Bidasee; Toshimichi Shinohara View Presentation 1149 - D0053. To determine changes in levels of cytokines in the anterior chamber (AC) fluid of eyes in patients with diabetic macular edema (DME)whom have been treated with repeated injections of ranibizumab (RBZ) Yasir J. Sepah; Mohamed A. Ibrahim; Alyssa Morimoto; Abeer Akhtar; Mauricio Maia; Kyu H. Hong; Montserrat Carrasco-Triguero; Diana V. Do; Menno van Lookeren Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 53 sur 222 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM Campagne; Quan Dong Nguyen View Presentation 1150 - D0054. Regulatory Effects of Mir365 and Bdnf in Müller Cells Involved in Diabetic Retina Lixia Lu; Juan Wang; Min Wang; Zongyi Li; Weiye Li; Guo-Tong Xu View Presentation 1151 - D0055. Identification of Downstream Targets of MicroRNA-184 in the Retina of a Type 1 Diabetes Model Yusuke Takahashi; Qian Chen; Anne Murray; Jian-Xing Ma View Presentation 1152 - D0056. THE PATHOGENIC ROLE OF DOWN-REGULATION OF PPAR-ΑLPHA EXPRESSION IN DIABETIC RETINOPATHY Yang Hu; Ying Chen; Lexi Ding; Xuemin He; Yusuke Takahashi; Rui Cheng; Yang Gao; Wei Shen; Qian Chen; Jian-Xing Ma View Presentation 1153 - D0057. High Glucose and Diabetes Modulate Cellular Proteasome Function: Implications in the Pathogenesis of Diabetes Complications Saeed Yadranji-Aghdam; Christine M. Sorenson; Nader Sheibani View Presentation 1154 - D0058. Apelin silencing exacerbated retinal edema in BRVO rats Wang Xinlei; Yong Tao; Yanrong Jiang View Presentation 1155 - D0059. Inhibition of Adenosine Kinase Attenuates Inflammation in Diabetic Retinopathy Nehal El-Sherbiny; Mohammad Naime; Saif Ahmad; Ahmed Elsherbini; Sadanand Fulzele; Mohammed M. Al-Gayyar; Laila A a. Eissa; Mamdouh El-Shishtawy; Gregory I. Liou View Presentation 1156 - D0060. Peripheral Retinal Perfusion and Functional Analysis of Patients with Ischemic Central Retinal Vein Occlusion Charles Wykoff; David M. Brown; Daniel Croft View Presentation 1157 - D0061. The Aqueous Humor Proteome in Patients with Diabetic Retinopathy Rachida Bouhenni; Deepak P. Edward; Sandeep Grover; Kakarla Chalam; Abby L. Sewell; Khaled K. Abu-Amero View Presentation 1158 - D0062. Polyunsaturated fatty acids and Plasmalogens in diabetics Philippe Koehrer; Niyazi Acar; Sarah Saab; Rodica Isaico; Alain M. Bron; Lionel Bretillon; Catherine P. Garcher View Presentation 1159 - D0063. TRANSGENIC AK-SMAA-GFP-HAR MICE SUPPORT THE PREMISE THAT ALDOSE REDUCTASE INITIATES DIABETIC RETINOPATHY Changmei Guo; Peng Zhang; Zifeng Zhang; Hiroyoshi Kawada; Karen Blessing; Peter F. Kador View Presentation 1160 - D0064. The significant relationships between Fibronectin, Tenascin-C and Periostin in the eyes of the patients with diabetic retinopathy Yukio Sassa; Shigeo Yoshida; Keijiro Ishikawa; Ryo Asato; Mitsuru Arima; Masanori Miyazaki; Hiroshi Enaida; Yuji Oshima; Toshihiro Kono; Tatsuro Ishibashi View Presentation 145. Retinal Regeneration and Cell Biology of the Retina and RPE - I Moderator(s): Andrew Fischer (Ohio State University) 1:00 PM - 2:45 PM; Exhibit / Poster Hall 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM Withdrawn 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM View Session Details 1161 - D0305. Synchronization of the Clock in RPE Cells Promotes Reentry into the Cell Cycle David J. Ramsey; Kathryn M. Ramsey; Demetrios Vavvas View Presentation 1162 - D0306. Reactive Gliosis in Adult Zebrafish Retinal Regeneration Jennifer Thomas; Xixia Luo; Ryan Thummel View Presentation 1163 - D0307. Molecular Mechanisms Underlying Müller Glia Dedifferentiation and Proliferation During Regeneration Of The Damaged Zebra Fish Retina David R. Hyde; Henry C. Conner; Ryne A. Gorsuch; Kristin M. Ackerman; Travis J. Bailey; Francis Raycroft; Craig M. Nelson View Presentation 1164 - D0308. The Role Of Rocks During Interkinetic Nuclear Migration In The Regenerating Adult Zebrafish Retina Manuela Lahne; Rebecca M. Marton; David R. Hyde View Presentation 1165 - D0309. bHLH transcription factor NeuroD is a non-cell autonomous regulator of cell cycle withdrawal during photoreceptor development and regeneration in the zebrafish retina Scott M. Taylor; James M. Fadool; Ryan Thummel; Peter F. Hitchcock View Presentation 1166 - D0310. Absence of ephrin-A2/A3 promotes photoreceptor regeneration in rhodopsin knockout mice Ruilin Zhu; Kin-Sang Cho; Yuan Fang; Christine Xu; Liu Yang; Dong F. Chen View Presentation 1167 - D0311. Synapses of the Outer Plexiform Layer in the Regenerating Zebrafish Retina Tim McGinn; Alessandra A. Minette; Tyler Lankford; Deborah L. Stenkamp View Presentation 1168 - D0312. Vitritis in pediatric retinal degenerations Maria Stunkel; Sajag Bhattarai; Edwin M. Stone; Kai Wang; Robert F. Mullins; Arlene V. Drack View Presentation 1169 - D0313. PERINUCLEAR AGGREGATION OF HUNTINGTIN PROTEIN (HTT) IS ASSOCIATED WITH PHOTORECEPTOR CELL DEATH IN DIABETES Shlomit Schaal; Qun Zeng; Tongalp H. Tezel View Presentation 1170 - D0314. Upregulation of P2X7 receptor expression by aging, lipopolysaccharide and interferon-γ in the retinal pigment epithelium Dongli Yang; Bota Cui; Susan G. Elner; Victor M. Elner View Presentation 1171 - D0315. Direct reprogramming of Human Fibroblasts into RPE and Photoreceptors Ilan Riess; Mark Gutierrez; Joe Reynolds; Deepak A. Lamba View Presentation 1172 - D0316. Expression and distribution of connexin50 in the mouse retina Birthe Dorgau; Helena Greb; Regina Herrling; Petra Bolte; Konrad Schultz; Reto Weiler; Ulrike Janssen-Bienhold View Presentation 1173 - D0317. Gene expression analysis between retinoblastoma with exophytic and endophytic growth patterns. Preliminary analysis Carlos-Alberto Rodriguez-Barrientos; Judith Zavala; Jorge E. Valdez; Victor Treviño; Juan E. Martinez-Ledesma View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 54 sur 222 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1174 - D0318. Transplanted Olfactory Ensheathing Cells Reduce Retinal Degeneration in a rat model of retinitis pigmentosa Zheng Qin Yin; Shu Jia Huo; Yao Chen Li; Jing Xie View Presentation 1175 - D0319. Anti-Senescent Effect of Photoreceptor Outer Segment Phagocytosis by Human Retinal Pigment Epithelial Cells In Vitro Murilo F. Roggia; Shiro Amano; Takashi Ueta View Presentation 1176 - D0320. HIF1 dependend upregulation of Stanniocalcin-2 in chronic and acute hypoxia in the retina Divya Ail; Christina Lange; Christian Grimm View Presentation 1177 - D0321. Retinal Tubulation and Detachment, Neovascularization and Retinal Pigment Epithelium Pathology in Slc4a5tvrm77 Mutant Mice Minzhong Yu; Mark P. Krebs; Lan Ying Shi; Jieping Wang; Wanda Hicks; Neal S. Peachey; Jürgen Naggert; Patsy M. Nishina View Presentation 1178 - D0322. FGF2 mediated inhibition of epithelial–to-mesenchyme transitions in cultured human fetal RPE Monte Radeke; Carolyn Radeke; Aaron M. Newman; Jane Hu; Dean Bok; Lincoln Johnson; Peter Coffey View Presentation 1179 - D0323. Altered expression of G-protein coupled receptors during oxygen-induced ischemic retinopathy James D. Kim; Yonju Ha; Hua Liu; Zhimin Xu; Audrey Nguyen; Bernard F. Godley; Ruth B. Caldwell; Wenbo Zhang View Presentation 1180 - D0324. Laminin Surface Matrix Promotes Superior Morphologic and Functional Characteristics in Cultured Human Retinal Pigment Epithelium Aya Yanagida; Jennifer R. Chao View Presentation 1181 - D0325. Thrombospondin-1 expression controls macrophage survival in the subretinal space Olivier Levy; William Raoul; Sophie Lavalette; Bertrand Calippe; Stéphane Germain; Xavier P. Guillonneau; Florian Sennlaub View Presentation 1182 - D0326. OXYTOCINERGIC SIGNALING IN THE RETINA Bikash R. Pattnaik; Patrick J. Halbach; Wenxiang Luo; De-Ann M. Pillers View Presentation 1183 - D0327. Compound 49b protects against blast-induced retinal injury Youde Jiang; Jena J. Steinle View Presentation 1184 - D0328. Pro-Inflammatory Cytokine Mixture Selectively Elevates miR-155 and Modulates RPE Physiology Congxiao Zhang; Arvydas Maminishkis; Tina Banzon; Sheldon S. Miller View Presentation 1185 - D0329. Hydroquinone Sensitizes Human RPE Cells to Basal Complement Attack by the Alternative Pathway Ping Yang; Peter Baciu; Glenn J. Jaffe View Presentation 1186 - D0330. Occludin Ser490 phosphorylation regulates endothelial cell growth control and angiogenesis Xuwen Liu; David A. Antonetti View Presentation 1187 - D0331. A 34-amino acid region of PEDF protects the RPE barrier from VEGFinduced breakdown Danielle Desjardins; Mohammad Dahrouj; Jason Kenealey; S Patricia Becerra; Yueying Liu; Kumar Sambamurti; Craig E. Crosson; Zsolt Ablonczy View Presentation 1188 - D0332. Expression of let-7 MicroRNA Family in the Aging Rat Retina and Vitreous Dania E. Hamassaki; Priscilla S. Akamine; Cesar S. Fuziwara; Carolina B. Del Debbio; Cristiano N. Pessoa; Edna T. Kimura View Presentation 1189 - D0333. Reversal photoisomerization of all-trans retinal in primary cultures of chicken retinal ganglion cells Nicolás Díaz; Luis P. Morera; Tomas C. Tempesti; Maria T. Baumgartner; Mario E. Guido View Presentation 1190 - D0334. Iron Loaded Melanosomes Change Antioxidant Enzyme Levels in ARPE19 Cells Anna K. Pilat; Christine Skumatz; Magdalena M. Olchawa; Mariusz Zareba; Janice M. Burke; Tadeusz J. Sarna View Presentation 1191 - D0335. Usher proteins contribute to cell-cell interactions between photoreceptors in the zebrafish retina Jennifer B. Phillips; Sabrina Toro; Marcel D. Rockwell; Monte Westerfield View Presentation 1192 - D0336. Toll-Like Receptor 3 (TLR3) protects the retina from oxidative stress Amit K. Patel; Abigail S. Hackam View Presentation 1193 - D0337. Epithelial Mesenchymal Transition and Human Vitreous Samples in 2D and 3D culture of ARPE-19 Cells Eri Takahashi; Takahiro Kawaji; Yasuhiro Ito; Hidenobu Tanihara View Presentation 1194 - D0338. Characterization of Human Ciliary Pigmented Epithelial (CPE) Cells Indumathi Mariappan; Mangalangi Udayakumar; Savitri Maddileti View Presentation 1195 - D0339. PREVENTIVE EFFECT OF A NUTRITIONAL SUPPLEMENT WITH RESVERATROL AND DHA IN CNV LASER-INDUCED MODEL Patricia Fernandez; Sergio Recalde; Alina A. Ivanescu; Laura Garcia-Garcia; Aitor Redondo-Exposito; Maite Moreno-Orduña; Vanessa Fernandez-Garcia; Alfredo GarciaLayana View Presentation 1196 - D0340. Cellular density of Myeloid Angiogenic Cells (MACs) alters their secretome profile and dictates angiogenic potential of retinal microvascular endothelium Sarah Wilson; Reinhold J. Medina; Christina L. O'Neill; Michelle O'Doherty; Jasenka Guduric-Fuchs; Alan W. Stitt View Presentation 1197 - D0341. Characterization of the nycthemeral expression profile of mRNAs and proteins implicated in daily phagocytosis of photoreceptor outer segments by the retinal pigment epithelium Jonathan Chatagnon; Celia Parinot; Emeline F. Nandrot View Presentation 1198 - D0342. Caspase-14 Expression Impairs Retinal Pigment Epithelial Cell Barrier Function Mohamed A. Al-Shabrawey; Sylvia Megyerdi; Pamela M. Martin; Nader Sheibani; Stephen Hsu View Presentation 1199 - D0343. The induction of NLRC4 Inflammasome Activation in Photoreceptor Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 55 sur 222 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM mitochondrial oxidative stress Sindhu Saraswathy; Narsing A. Rao View Presentation 1200 - D0344. Expression of Neonatal Fc Receptor in the Eye Michael B. Powner; Jenny Mckenzie; Derry Roopenian; Marcus Fruttiger View Presentation 1201 - D0345. Efficient, Tamoxifen-inducible, Cre-recombinase Activation in Resident Retinal Microglia Andrew Scott; Michael B. Powner; Marcus Fruttiger View Presentation 1202 - D0346. The Small Heat Shock Protein αB-crystallin is required for Exosome Biogenesis in Adult Human Retinal Pigment Epithelial Cells Suraj P. Bhat; Rajendra K. Gangalum; Ishanee Dighe; Ivo Atanasov; Z Hong Zhou; Larry L. David View Presentation 1203 - D0347. A single valine residue plays a critical role in peripherin/rds targeting to photoreceptor outer segments Raquel Y. Salinas; Sheila A. Baker; Sidney Gospe; Vadim Y. Arshavsky View Presentation 146. Neuro-Ophthalmology: Hereditary and Congenital Disease Moderator(s): Alfredo Sadun (Doheny Eye Institute) 1:00 PM - 2:45 PM; Exhibit / Poster Hall 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM 1:00 PM - 2:45 PM View Session Details 1204 - D0382. Reduced expression of the OPA1 gene due to a novel p.Q31X nonsense mutation leads to autosomal dominant optic atrophy Monika Oldak; Aneta Federowicz; Kamil Szulborski; Katarzyna Rydz; Joanna Wierzbowska; Joanna Kosinska; Marek Rekas; Rafal Ploski; Jacek P. Szaflik; Jerzy Szaflik View Presentation 1205 - D0383. Neurological and neuroradiological alterations in OPA1-linked dominant optic atrophy patients agathe roubertie; Nicolas Leboucq; Hervé Brunel; Emmanuelle Lebars; Michel Mondain; Patrizia Amati Bonneau; Max Villain; Isabelle Meunier; Guy Lenaers; Christian P. Hamel View Presentation 1206 - D0384. Ganglion Cell-Inner Plexiform Layer Thickness and Retinal Nerve Fiber Layer Thickness in Patients with Autosomal Dominant Optic Atrophy Cecilia Rönnbäck; Michael Larsen View Presentation 1207 - D0385. Treatment of Leber’s hereditary optic neuropathy patients with EPI-743 prevents decline of the serum biomarker - neuron specific enolase Edward R. Chu; Fred N. Ross-Cisneros; Jeong Goo Lee; Kenneth M. Yee; Carlos F. Chicani; Katsuyuki Murase; Martin Thoolen; Guy Miller; Alfredo A. Sadun View Presentation 1208 - D0386. Linkage analysis in Leber’s hereditary optic neuropathy (LHON): failure to locate significant loci in a very large family indicates a polygenic/environmental complex contribution to penetrance Valerio Carelli; Leonardo Caporali; Alessandra Maresca; Maria L. Valentino; Solange R. Salomao; Alfredo A. Sadun; Pio d'Adamo View Presentation 1209 - D0387. Macula structure in patients with optic disc oedema and optic nerve head drusen Anastasia Pilat; Frank A. Proudlock; Periyasamy Kumar; Irene Gottlob View Presentation 1210 - D0388. Long term data challenges the safety and efficacy of radial optic neurotomy in patients with optic nerve drusen Tony Lin; Ian McIlraith; David Nicolle; Tom Sheidow View Presentation 1211 - D0389. The Prenatal, Ophthalmologic and Neurologic Profile in Patients with Optic Nerve Hypoplasia and Septo-Optic Dysplasia Abraham Anaya-Olvera; Jans J. Fromow-Guerra; Virgilio Morales-Canton; Cristina Villanueva-Mendoza View Presentation 1212 - D0390. Ophthalmologic and neuroendocrinologic findings in children with septooptic dysplasia Antonio Bergua; Helmuth G. Doerr; Konstanze Stuhlfelder View Presentation 1213 - D0391. Photorefractive keratectomy in ocular infantile nystagmus syndrome Michela Fresina; giuseppe giannaccare; Emilio C. Campos View Presentation 1214 - D0392. Magnocellular Visual Pathway Deficit In Dyslexia: Analysis Of Possible Patterns Of Visual Field Alterations Tested With Frequency Doubling Illusion Fernando O. Avellis; Alessandra Dassò; Arturo Carta; Vincenzo Scorcia; Stefano A. Gandolfi View Presentation 1215 - D0393. Retinal and Optic Nerve Findings in a Family with Chediak-Higashi Syndrome Scott E. Brodie; James Weisfeld-Adams; Catherine Cho; Janet C. Rucker View Presentation 147. Genetics Group: Advances in the Genetics of Common Ocular Disorders with Complex Inheritance Moderator(s): Janey Wiggs (Mass Eye & Ear Infirmary), John Fingert (University of Iowa) and R Rand Allingham (Duke University Eye Center) 1:00 PM - 2:30 PM; TCC LL 4/5 View Session Details Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary 1:00 PM - 1:05 PM Introduction Include in Itinerary 1:05 PM - 1:22 PM Myopia Christopher J. Hammond View Presentation Genome-Wide Association Analyses Identify Multiple Loci Associated with Central Corneal Thickness and Keratoconus Stuart MacGregor View Presentation Primary Open Angle Glaucoma Terry Gaasterland View Presentation Angle-closure Glaucoma Tin Aung View Presentation Advances in the Genetics of Age-Related Macular Degeneration Sudha K. Iyengar View Presentation Include in Itinerary 1:22 PM - 1:39 PM 1:39 PM - 1:56 PM 1:56 PM - 2:13 PM 2:13 PM - 2:30 PM 148. Veterans Vision and TBI (Traumatic Brain Injury) Moderator(s): Donald Gagliano (DOD/VA Vision Center of Excellence) 1:00 PM - 2:30 PM; 6E View Session Details Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Presentation 28/03/2013 Abstract Central Page 56 sur 222 1:00 PM - 1:23 PM 1:23 PM - 1:45 PM 1:45 PM - 2:07 PM 2:07 PM - 2:30 PM Randy H. Kardon View Presentation Presentation Ann K. McKee View Presentation Presentation Elaine R. Peskind View Presentation Presentation Lee E. Goldstein View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 149. EVER/ARVO Workshop: Oxidative Stress in the Eye Moderator(s): Leopold Schmetterer (Medical University of Vienna) and Alan Stitt (Queens University Belfast) 1:00 PM - 2:30 PM; 606/607 1:00 PM - 1:18 PM 1:18 PM - 1:36 PM 1:36 PM - 1:54 PM 1:54 PM - 2:12 PM 2:12 PM - 2:30 PM The Role of Advanced Glycation/lipoxidation in the Pathogenesis of Diabetic Retinopathy Alan W. Stitt View Presentation Glaucomatous Outflow and Oxidative Stress Alberto Izzotti View Presentation RPE and Oxidative Stress Olaf Strauss View Presentation Glial Cells and Oxidative Stress Antje Grosche View Presentation Oxidative Stress in Ageing and Retinal Degenerations Colm J. O'Brien View Presentation 150. For Me, or Not For Me: That Is the Question - Industry Funding for Research and Education Moderator(s): Peter Koulen (University of Missouri-Kansas City) and Brian Levy (Aerie Pharmaceuticals) 1:00 PM - 2:30 PM; 611-614 1:00 PM - 1:15 PM 1:15 PM - 1:30 PM 1:30 PM - 1:45 PM 1:45 PM - 2:00 PM 2:00 PM - 2:30 PM View Session Details View Session Details Collaborative Experience with Bausch & Lomb Steven E. Feldon; Brian Levy View Presentation The New NIH-Industry Pilot Program and New Funding Initiatives at NIH and NEI Jerome Wujek View Presentation Research Collaborations with Industry: Guidelines for Success Scott M. Whitcup View Presentation Intellectual Property Development from Collaborations between Industry and Academia William P. Ramey View Presentation Discussion and Q&A Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Showing 1 - 50 of 59 See More... MONDAY, MAY 06, 2013 201. Photoreceptor Cilium and Ciliopathies View Session Details Moderator(s): Maxim Sokolov (West Virginia Univ Eye Institute) and Alecia Gross (Univ of Alabama at Birmingham) 8:30 AM - 10:15 AM; 6A 1223. Nucleotide Binding Status of rab11a Affects its Localization in Rods and its Ability to Associate with Outer Segment Membranes Nicholas J. Reish; Alecia K. Gross View Presentation 8:45 AM - 9:00 AM 1224. NUDC is a novel component of the rab11a-rhodopsin interaction in the inner segment Alecia K. Gross; Nicholas J. Reish View Presentation 9:00 AM - 9:15 AM 1225. Addressing the Role of PhLP in the Folding and Assembly of G-protein βγ dimer Maxim Sokolov; Satyabrata Sinha; Marycharmain Belcastro; Xueli Gao View Presentation 9:15 AM - 9:30 AM 1226. Light-Dependent Phosphorylation of BBS5 in Photoreceptors and Its Interaction with Arrestin1 Tyler S. Smith; Donald R. Dugger; Susan N. Bolch; J Hugh McDowell; W Clay Smith View Presentation 1227. The Essential Role of CCT in Outer Segment Morphogenesis 9:30 AM - 9:45 AM Satyabrata Sinha; Marycharmain Belcastro; Seongjin Seo; Maxim Sokolov View Presentation 9:45 AM - 10:00 AM 1228. The farnesylated small GTPase RAB28 is mutated in autosomal recessive conerod dystrophy Susanne Roosing; Klaus Rohrschneider; Avigail Beryozkin; Nicole Weisschuh; Susanne Kohl; Bernd Wissinger; Eyal Banin; Frans P. Cremers; Anneke I. Den Hollander View Presentation 8:30 AM - 8:45 AM 203. Fibrosis in Glaucoma: Mechanisms and Therapy - Minisymposium Moderator(s): Colm O'Brien (Mater Misericordiae Univ Hospital) and Abbot Clark (University of North Texas HSC) 8:30 AM - 10:15 AM; 6B 8:30 AM - 8:50 AM 8:50 AM - 9:04 AM 9:04 AM - 9:18 AM 9:18 AM - 9:32 AM View Session Details 1229. Mechanisms in Fibrosis: Cast a Cold Eye on the Myofibroblast Boris Hinz View Presentation 1230. Conjunctival Fibrosis Following Glaucoma Surgery Gunther R. Schlunck View Presentation 1231. Trabecular Meshwork Extracellular Matrix Changes in Glaucoma Abbot F. Clark View Presentation 1232. The Role of the Trabecular Meshwork and Growth Factors in Glaucoma Ernst R. Tamm View Presentation Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 57 sur 222 1233. Connective Tissue Changes in the Optic Nerve Head and Peri-Papillary Sclera in Glaucoma Harry Quigley View Presentation 9:46 AM - 10:00 AM 1234. Role of Lamina Cribrosa Cells in ONH Fibrosis Deborah M. Wallace View Presentation 1235. Role of Optic Nerve Astrocytes 10:00 AM - 10:14 Rudolf Fuchshofer AM View Presentation 9:32 AM - 9:46 AM 205. DME: Clinical Research Moderator(s): Jayashree Sahni (University of Liverpool) and Usha Chakravarthy (Queens University of Belfast) 8:30 AM - 10:15 AM; 6E View Session Details 1236. Intraocular Pressure Trends Following Intravitreal Injections of Anti-VEGF Agents for Diabetic Macular Edema Abdulelah A. Al-Abdullah; Sawsan R. Nowilaty; Nicola G. Ghazi View Presentation 8:45 AM - 9:00 AM 1237. Associations of Serum Lipids with Macular Morphology in Patients without Diabetic Macular Edema Mariko Sasaki; Motoko Kawashima; Ryo Kawasaki; Miho Kawai; Atsuro Uchida; Takashi Koto; Hajime Shinoda; Kazuo Tsubota; Jie Wang; Yoko Ozawa View Presentation 9:00 AM - 9:15 AM 1238. Evaluating SAVE, a novel grading protocol for the treatment of diabetic macular edema Sonja G. Prager; Matthias Bolz; Gabor Deak; Andreas Pollreisz; Berthold Pemp; Katharina Kriechbaum; Christoph D. Scholda; Ursula Schmidt-Erfurth View Presentation 9:15 AM - 9:30 AM 1239. Double-Masked Trial Demonstrates Superiority Of Combined Ranibizumab Plus Laser Versus Laser In Patients With Diabetic Macular Edema With Or Without Proliferative Diabetic Retinopathy Chris P. Lohmann; Jessica Voegeler; Sandra Liakopoulos; Peter M. Wiedemann; Georg Spital; Gabriele E. Lang View Presentation 9:30 AM - 9:45 AM 1240. Combination of Ranibizumab and Navigated Retinal Photocoagulation in Diabetic Macular Edema, compared to Ranibizumab Mono-Therapy: Twelve Month Results Sarah Cserhati; Raffael Liegl; Michael W. Ulbig; Christos Haritoglou; Anselm Kampik; Aljoscha S. Neubauer; Marcus Kernt View Presentation 9:45 AM - 10:00 AM 1241. Clinically significant improvement in visual acuity and predictors of early vision gains in the RIDE and RISE Phase III trials of ranibizumab for diabetic macular edema Lawrence S. Morse; Linda Yau; Lisa Tuomi; Jason S. Ehrlich View Presentation 8:30 AM - 8:45 AM 206. CNV: Clinical and Translational Research Moderator(s): James Folk (Univ of Iowa Hospitals & Clinics) and Stephen Kim (Vanderbilt University) 8:30 AM - 10:15 AM; 6C View Session Details 1242. Suppression of experimental choroidal neovascularization by curcumin in mice Ping Xie; Qinghuai Liu; Songtao Yuan; Qing Yang; Weiwei Zhang View Presentation 8:45 AM - 9:00 AM 1243. Comparison of Ocular Pharmacokinetics of Brimonidine and Dexamethasone in Normal Animal vs. Animal Models with Choroidal Neovascularization Jie Shen; Chandrasekar Durairaj; Ton Lin; Yan Liu; James A. Burke View Presentation 9:00 AM - 9:15 AM 1244. Functional study of microRNA-24 in ocular angiogenesis Qinbo Zhou; Ashwath Jayagopal; Shusheng Wang View Presentation 9:15 AM - 9:30 AM 1245. Impact of Ranibizumab on Patient-Reported Visual Functioning in Myopic Choroidal Neovascularization: 3- and 6-Month Results Kyoko Ohno-Matsui; Nikolle Tan; Tien Y. Wong; Tatsuro Ishibashi; Jennifer Petrillo; Neil M. Bressler; Claudia Leteneux View Presentation 1246. Activated Histoplasmosis Scars 9:30 AM - 9:45 AM James C. Folk; Matthew A. Cunningham; Michael D. Abramoff; Elliott H. Sohn View Presentation 9:45 AM - 10:00 AM 1247. Twelve-month efficacy and safety of ranibizumab 0.5 mg(RBZ) versus verteporfin photodynamic therapy(vPDT) in the treatment of visual impairment(VI) due to choroidal neovascularization(CNV) secondary to pathologic myopia(PM) Francesco Bandello View Presentation 8:30 AM - 8:45 AM 208. The Untapped Immunomodulating Potential of Neuropeptides Minisymposium Moderator(s): Andrew Taylor (Boston Univ School of Medicine) and Linda Hazlett (Wayne State Univ Sch of Med) 8:30 AM - 10:15 AM; 606/607 View Session Details 1248. VIP and PACAP effects on macrophages and T cell cytokine production Doina Ganea View Presentation 8:51 AM - 9:12 AM 1249. Modulation of Ocular Immunobiology by the Neuropeptide alpha-Melanocyte Stimulating Hormone Andrew W. Taylor View Presentation 9:12 AM - 9:33 AM 1250. CGRP Nerves are a Major Target for Neuroptotection D1 in Cornea Nerve Regeneration Haydee E. Bazan View Presentation 9:33 AM - 9:54 AM 1251. VIP and SP in Corneal Infection Linda D. Hazlett View Presentation 9:54 AM - 10:15 AM 1252. Substance P mediated regulation of herpes simplex keratitis Susmit Suvas View Presentation 8:30 AM - 8:51 AM 210. Retinoblastoma: Pre-Clinical Models and Targeted Therapies Moderator(s): Patricia Chevez-Barrios (Methodist Hospital) and Rachel Brennan (St Jude Children s Research Hospital) 8:30 AM - 10:15 AM; 608 8:30 AM - 8:45 AM 8:45 AM - 9:00 AM View Session Details 1253. In vivo imaging and characterization of an orthotopic retinoblastoma xenograft model Timothy W. Corson; Anna J. Geary; Andrea Wenzel; Amanda Riley; Brian P. McCarthy; Barbara Bailey; Karen E. Pollok; Paul R. Territo; Brian C. Samuels View Presentation 1254. An Orthotopic Transplantation Model of Retinoblastoma in Zebrafish: A Novel Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 58 sur 222 Gateway for Screening of Anticancer Drugs Dong Hyun Jo; Dain Son; Yirang Na; Manyoung Jang; Jae-Hoon Choi; Jin Hyoung Kim; Young S. Yu; Seung Hyeok Seok; Jeong Hun Kim View Presentation 9:00 AM - 9:15 AM 1255. Expression of Pluripotent Markers L1CAM and SSEA-5, Common to Human Retinoblastomas, Xenografts, Teratomas, Embryonic Tumors and Induced Pluripotent Stem Cells Gail M. Seigel; Meerim Choi; Rui Chang; Jason S. Meyer; Bruce R. Ksander; Paraskevi E. Kolovou; Nadine E. de Waard; Linda L. Cassidy View Presentation 9:15 AM - 9:30 AM 1256. Evaluation of response to Carboplatin in putative Cancer Stem Cells of Retinoblastoma Y79 cell line Geeta K. Vemuganti; Rohini M. Nair; Murali Mohan Sagar Balla; Santosh Honavar; Mohammad J. Ali; Vijay Anand R. Palkonda View Presentation 9:30 AM - 9:45 AM 1257. High Risk Retinoblastoma: Correlation Between Expression of Angiogenic Factors and Neovascular Glaucoma Claudia M. Prospero Ponce; Dan S. Gombos; Aravindh S. Ganapathy; Patricia ChevezBarrios View Presentation 9:45 AM - 10:00 AM 1258. Development of sd-rxRNA® for Retinoblastoma Therapy Michael Byrne; Hardeep P. Singh; Donglai Qi; James Cardia; Lakshmipathi Pandarinathan; Katherine Holton; Karen Bulock; Lyn Libertine; David Cobrinik; Pamela A. Pavco View Presentation 1259. KZ-41 prevents melphalan-induced intercellular adhesion molecule-1 (ICAM-1) 10:00 AM - 10:15 upregulation and apoptosis in retinal endothelial cells AM Qiuhua Zhang; Jordan J. Toutounchian; Charles R. Yates; Matthew W. Wilson; Jena J. Steinle View Presentation 212. Cataract I Moderator(s): Paul Donaldson (University of Auckland) and Marjorie Lou (University of Nebraska) 8:30 AM - 10:15 AM; 609 View Session Details 1260. A recessive congenital cataract results from an unstable connexin mutant Viviana M. Berthoud; Peter J. Minogue; Eric C. Beyer View Presentation 8:45 AM - 9:00 AM 1261. The role of HIF-1α/-2α and VEGF in lens epithelial cell survival in hypoxia Patrick R. Cammarata; Sudha Neelam; Morgan M. Brooks View Presentation 9:00 AM - 9:15 AM 1262. Cataract Extraction Outcomes and the Prevalence of Zonular Insufficiency in Retinitis Pigmentosa Clement C. Chow; Mark S. Dikopf; William F. Mieler; Elmer Y. Tu View Presentation 9:15 AM - 9:30 AM 1263. The role of periaxin genetic variances in cataract formation of Gja3 knockout mice Xiaohua Gong; Jing Zeng; Catherine Cheng; Chun-hong Xia View Presentation 9:30 AM - 9:45 AM 1264. The Topical Nutraceutical Optixcare EH Protect Rats Against Ocular Oxidative Stress Peter F. Kador; Changmei Guo; Hiroyoshi Kawada; Karen Blessing View Presentation 9:45 AM - 10:00 AM 1265. A mutation in a RABGAP is responsible for cataracts in the blind-sterile (bs) mouse and Warburg micro syndrome patients Duska J. Sidjanin; Bo Chang; Ryan P. Liegel View Presentation 1266. Changes in the Pattern of DNA Methylation in Age-Related Cataract 10:00 AM - 10:15 Peng Zhou; Yi Lu AM View Presentation 8:30 AM - 8:45 AM 214. Neuroprotection in the Retina and RPE Moderator(s): Leonard Levin (McGill University) and Janis Eells (Univ of Wisconsin Milwaukee) 8:30 AM - 10:15 AM; 611-614 View Session Details 1267. Photobiomodulation Preserves Mitochondrial Redox State and is Retinoprotective in a Rodent Model of Retinitis Pigmentosa Janis T. Eells; Sandeep Gopalakrishnan; Mahsa Ranji; Sepideh Maleki; Betsy Abroe; Heather Schmitt; Adam M. Dubis; Phyllis Summerfelt; Joseph Carroll View Presentation 8:45 AM - 9:00 AM 1268. Cytochrome P450 2C9 Is a Target for Photoreceptor Neuroprotection Qing Chang; Siquan Chen ; Bogaard Joseph; Dingcai Cao; Michael A. Grassi View Presentation 9:00 AM - 9:15 AM 1269. Aerobic Exercise Preserves Retinal Function and Structure in Light Induced Retinal Degeneration Model Eric C. Lawson; Moon K. Han; Jana T. Sellers; Micah A. Chrenek; Serena S. Jafer; Jeffrey H. Boatright; Machelle T. Pardue View Presentation 9:15 AM - 9:30 AM 1270. CNTF-mediated Neuroprotection in a Mouse Model of Retinitis Pigmentosa Promotes Outer Segment Elongation and Requires Cytokine Receptor gp130 Initially in Müller Glial Cells Kun Do Rhee; Dean Bok; Steven Nusinowitz; Kevin Chao; Xian-Jie Yang View Presentation 9:30 AM - 9:45 AM 1271. The hormone prolactin: a novel endogenous trophic factor able to limit retinal degeneration Stephanie Thebault; Edith Arnold; Andrés Quintanar-Stéphano; Gerardo Rojas-Piloni; Miguel Condés-Lara; Nadine Binart; Gonzalo Martinez de la Escalera; Carmen Clapp View Presentation 9:45 AM - 10:00 AM 1272. Both caspase-dependent and capase-independent cell death pathways are involved in neuronal death in rat retinas exposed to AGEs Guzel Bikbova; Toshiyuki Oshitari; Shuichi Yamamoto View Presentation 8:30 AM - 8:45 AM 10:00 AM - 10:15 AM 1273. Ca2+ signaling in retinal ganglion cells and their axons Allison Sargoy; Luis Pérez de Sevilla Müller; Steven A. Barnes; Nicholas Brecha View Presentation 216. Peptides and Polypeptides in Ocular Health and Dysfunction Minisymposium Moderator(s): Naj Sharif (Alcon Research Ltd ) and Claudio Bucolo (University of Catania) 8:30 AM - 10:15 AM; 618-620 View Session Details Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary 8:30 AM - 8:35 AM Introduction Include in Itinerary 8:35 AM - 8:55 AM 1274. Peptides in the Eye: An Overview Miguel Coca-Prados View Presentation 1275. VEGF and PDGF: Roles in Physiology and Pathology Patricia A. D'Amore Include in Itinerary 8:55 AM - 9:15 AM Include in Itinerary 28/03/2013 Abstract Central Page 59 sur 222 View Presentation 1276. Endothelin: Friend or Foe? Thomas Yorio View Presentation 9:35 AM - 9:55 AM 1277. Opioid and Natriuretic Peptide Axis: Nature’s Ocular Neuroprotectants Shahid Husain View Presentation 9:55 AM - 10:15 AM 1278. Bradykinin: A Peptide for All Seasons Naj Sharif View Presentation 9:15 AM - 9:35 AM 218. Aberrations, Image Quality and Visual Performance Moderator(s): Harilaos Ginis (University of Crete) and Jens Buehren (Goethe University Frankfurt) 8:30 AM - 10:15 AM; TCC LL 4/5 View Session Details 1279. Optical quality metrics predictive of visual acuity for the design of wavefront guided corrections in the presence of dynamic registration uncertainty Yue Shi; Raymond A. Applegate; Ayeswarya Ravikumar; Harold E. Bedell View Presentation 8:45 AM - 9:00 AM 1280. Influence of aberration-induced blur on contrast sensitivity: comparison of different optotype sizes Jens Buehren; Hendrik Jungnickel; Wolfgang Raab; Daniel Weigel; Michael Gebhardt; Richard Kowarschik; Thomas Kohnen View Presentation 9:00 AM - 9:15 AM 1281. Visual performance under natural, corrected and Adaptive Optics induced astigmatism: meridional and adaptational effects Maria Vinas; Pablo De Gracia; Carlos Dorronsoro; Lucie Sawides; Gildas Marin; Martha Hernandez; Susana Marcos View Presentation 9:15 AM - 9:30 AM 1282. Perceptual learning after correcting the eye’s aberration with adaptive optics Ramkumar Sabesan; Geunyoung Yoon View Presentation 9:30 AM - 9:45 AM 1283. What is the smallest change in visual acuity that is correlated with a change in image quality? Ayeswarya Ravikumar; Jason D. Marsack; Yue Shi; Raymond A. Applegate View Presentation 9:45 AM - 10:00 AM 1284. Determination of Customized Aberration Thresholds Carmen Canovas; Patricia A. Piers; Silvestre Manzanera; Christina Schwarz; Pedro M. Prieto; Henk A. Weeber; Pablo Artal View Presentation 1285. Impact of the Retinal Reflection on the Wide-Angle Point Spread Function of the 10:00 AM - 10:15 Human Eye AM Harilaos S. Ginis; Guillermo M. Perez; Alexandros Pennos ; Juan M. Bueno; Pablo Artal View Presentation 8:30 AM - 8:45 AM 220. Immunology, Allergy, Neovascularization Moderator(s): Frank Larkin (Moorfields Eye Hospital) and Thomas Ritter (Nt'l Univ of Ireland, Galway) 8:30 AM - 10:15 AM; TCC 303 View Session Details 1286. Lens-derived Sema3A inhibits angioblast migration and vascularization of the developing cornea Peter Y. Lwigale; Chelsey McKenna View Presentation 8:45 AM - 9:00 AM 1287. Cornea Intravital Multiphoton Visualization of the Resident Mononuclear Phagocyte Network in Allergy Tomas Blanco; Matthew Kan; Michael Gunn; Daniel R. Saban View Presentation 9:00 AM - 9:15 AM 1288. Intravital Multiphoton Microscopy of Corneas and Draining Lymph Nodes Shows Increased Velocity of Dendritic Cells after Corneal Transplantation and Directionality in Corneal Allografts Takefumi Yamaguchi; Kai Hu; Deshea L. Harris; Pedram Hamrah View Presentation 9:15 AM - 9:30 AM 1289. The CCR7-CCL19/CCL21 Axis Mediates Enhanced Antigen-Presenting Cell Trafficking In High-Risk Corneal Transplantation Jing Hua; William Stevenson; Thomas H. Dohlman; Narghes Calcagno; Negar Pirmadjid; Zahra Sadrai; Sunil K. Chauhan; Daniel R. Saban; Reza Dana View Presentation 9:30 AM - 9:45 AM 1290. Understanding the Mechanism of Donor Bone Marrow Derived Dendritic Cells in Promoting Corneal Allograft Survival in the Rat Thomas Ritter; Oliver Treacy; Aideen Ryan; Mourice Morcos; Marese Cregg; Mikhail Nosov; Lisa O'Flynn View Presentation 1291. Influences on effector functions of monocyte-derived macrophages in corneal 9:45 AM - 10:00 AM allograft rejection Thabo Lapp; Nandi Simpson; Sarah Zaher; Benjamin Chain; Thomas Reinhard; Mahdad Noursadeghi; Frank Larkin View Presentation 1292. MMP12 Regulation of Corneal Inflammation 10:00 AM - 10:15 Matilda F. Chan; Jeffrey Lin; Neeraj Ramakrishnan; Zena Werb AM View Presentation 8:30 AM - 8:45 AM 222. Retinal Circuits and Visual Responses Moderator(s): Jonathan Demb (Yale University) and William Taylor (Oregon Health Sciences University) 8:30 AM - 10:15 AM; TCC 304 8:30 AM - 8:30 AM View Session Details Alternate for Park is Borghuis; Jason Chen also wanted talk 1293. Asymmetries between ON and OFF responses in primate vision first arise in photoreceptors Juan Angueyra; Fred Rieke View Presentation 8:45 AM - 9:00 AM 1294. In vivo optical recording of the light response of primate ganglion cells Lu Yin; Benjamin D. Masella; Deniz Dalkara; Jie Zhang; John G. Flannery; David V. Schaffer; David R. Williams; William H. Merigan View Presentation 9:00 AM - 9:15 AM 1295. Response properties of broad thorny ganglion cells in the primate retina Christian Puller; Michael B. Manookin; Maureen Neitz; Fred Rieke; Jay Neitz View Presentation 9:15 AM - 9:30 AM 1296. ON parasol ganglion cells of the primate retina exhibit directional sensitivity Michael B. Manookin; Christian Puller; Fred Rieke; Jay Neitz; Maureen Neitz View Presentation 9:30 AM - 9:45 AM 1297. Direction tuning of bipolar cell glutamate release onto direction-selective ganglion cells in mouse retina Silvia Park; Bart G. Borghuis; In-Jung Kim; Loren L. Looger; Jonathan B. Demb View Presentation 9:45 AM - 10:00 AM 1298. Form and function of the three ON-type direction-selective retinal ganglion cells in 8:30 AM - 8:45 AM Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 60 sur 222 10:00 AM - 10:15 AM the Hoxd10 mouse Maureen E. Estevez; Lauren E. Quattrochi; Onkar S. Dhande; Inkyu Kim; Timothy Firman; Rana Eldanaf; Andrew D. Huberman; David M. Berson View Presentation 1299. Recording the entire visual representation along the vertical pathway in the retina Tom Baden; Philipp Berens; Matthias Bethge; Thomas Euler View Presentation 224. Strabismus/Eye Movements Moderator(s): Linda McLoon (University of Minnesota) and Avery Weiss (Seattle Children's Hospital / W-7729) 8:30 AM - 10:15 AM; TCC 305 View Session Details 1300. Health-Related Quality of Life in Diplopic Patients Treated With Prism Jonathan M. Holmes; Sarah R. Hatt; David A. Leske; Laura Liebermann View Presentation 8:45 AM - 9:00 AM 1301. Displacement of Optical Centers in Over-the-Counter Readers: A Potential Cause of Diplopia Constance E. West; David G. Hunter View Presentation 9:00 AM - 9:15 AM 1302. Magnetic Resonance Imaging (MRI) Demonstrates Differential Compartmental Contractility of Medial Rectus Muscle During Vertical Duction Joseph L. Demer; Robert A. Clark View Presentation 9:15 AM - 9:30 AM 1303. A Morphometric Analysis of the Inferior Oblique Muscle in Patients with Inferior Oblique Overaction Linda K. McLoon; Joost Felius; David R. Stager View Presentation 9:30 AM - 9:45 AM 1304. Globe Excyclorotation in Crouzon Syndrome: Relationship to Pattern Strabismus and Apparent Inferior Oblique Overaction Avery H. Weiss; John P. Kelly; James O. Phillips View Presentation 9:45 AM - 10:00 AM 1305. Visual fixation as an objective measure of visual acuity in infants Amithavikram R. Hathibelagal; Moshe Eizenman; Elizabeth L. Irving; Susan J. Leat View Presentation 1306. Visual Acuity Deficit in Idiopathic Infantile Nystagmus Associated with Current 10:00 AM - 10:15 Foveation Characteristcs and History of Deprivation AM Joost Felius; Zainab A. Muhanna View Presentation 8:30 AM - 8:45 AM 227. Genetics of Inherited Eye Disease Moderator(s): Stephen Daiger (Univ Texas Hlth Sci Ctr Houston) and Eric Pierce (Massachusetts Eye and Ear Infirmary) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 1307 - A0001. Overview of genetic causes and identification of novel loci for retinal dystrophies in Pakistan Muhammad I. Khan; Maleeha Azam; Muhammad Ajmal; Rob W. Collin; Raheel Qamar; Anneke I. Den Hollander; Frans P. Cremers View Presentation 1308 - A0002. Genome-Wide Association Analysis of Canine Retinal Dysplasia and Vitreous Degeneration Saija Ahonen; Hannes Lohi View Presentation 1309 - A0003. Identification of Novel Homozygous Deletions in Consanguineous Pedigrees as a Shortcut to Candidate Gene Discovery in Retinal Dystrophies Kristof Van Schil; Françoise Meire; Thomy de Ravel; Bart P. Leroy; Hannah Verdin; Frauke Coppieters; Elfride De Baere View Presentation 1310 - A0004. Novel de novo mutations in CRX gene associated with Leber congenital amaurosis in Chinese patients Ruifang Sui; Xuan Zou; Fangtian Dong View Presentation 1311 - A0005. RDH12 mutations associated with Leber congenital amaurosis and earlyonset severe retinal dystrophy in Chinese patients Xuan Zou; Fangtian Dong; Ruifang Sui View Presentation 1312 - A0006. NMNAT1 p.Arg237Cys mutation in Japanese patients with Leber congenital amaurosis Tomoka Kambe; Takuro Fujimaki; Shuri Kawamorita; Eisuke Arai; Ai Miyazaki; Keiko Fujiki; Fumino Iwata; Chieko Tamura; Akira Murakami View Presentation 1313 - A0007. Regulatory mutations in the 5’UTR of NMNAT1, encoding the nuclear isoform of nicotinamide nucleotide adenylyltransferase 1, cause Leber Congenital Amaurosis Frauke Coppieters; Annelot Baert; Caroline Van Cauwenbergh; Miriam Bauwens; Sarah De Jaegere; Thomy de Ravel; Françoise Meire; Bart P. Leroy; Elfride De Baere View Presentation 1314 - A0008. Wasf3 is required for photoreceptor sensory cilia (PSC) formation Jingfa Zhang; Qi Zhang; Conghui Zhang; Chan Wu; Eric A. Pierce; Qin Liu View Presentation 1315 - A0009. A 353-bp Alu insertion in MAK is a prevalent cause of recessive retinitis pigmentosa in North American Jewish patients Carlo Rivolta; Giulia Venturini; Shyana Harper; Hanna Koskiniemi; Eliot L. Berson View Presentation 1316 - A0010. Clinical and Molecular Findings in Japanese Cases with KCNV2retinopathy: Report of Novel Variants Yu Kato; Kaoru Fujinami; Natsuko Nakamura; Masakazu Akahori; Takeshi Iwata; Kazushige Tsunoda View Presentation 1317 - A0011. Bioinformatic identification of altered splicing motifs resulting from the Alu insertion in exon 9 of the RP gene MAK S Scott Whitmore; Shemin Zeng; Heather T. Daggett; Adam P. DeLuca; Budd A. Tucker; Terry A. Braun; Robert F. Mullins; Edwin M. Stone; Todd E. Scheetz View Presentation 1318 - A0012. Extended Phenotypic Characteristics of NR2E3-related Enhanced S-cone Syndrome Ajoy Vincent; Cynthia VandenHoven; Carol A. Westall; Elise Heon View Presentation 1319 - A0013. Phenotypic variability in paediatric cases of enhanced S-cone syndrome (ESCS) Gavin Arno; Panagiotis I. Sergouniotis; Arundhati Dev Borman; Aman Chandra; Graham E. Holder; Anthony G. Robson; Andrew R. Webster; Anthony T. Moore View Presentation 1320 - A0014. Exon 3 genotypes of OPN1LW/OPN1MW associated with X-linked congenital cone dysfunction Susanne Kohl; Britta Baumann; Christian P. Hamel; Peter Gustavsson; Thomas Rosenberg; Astrid S. Plomp; Bart P. Leroy; Joke BGM Verheij; Bernd Wissinger View Presentation 1321 - A0015. Fine analysis of the deletions in red/green opsin genes and the upstream Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 61 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM locus control region (LCR) found in two Japanese families with blue cone monochromacy (BCM) Chun-xia Wang; Katsuhiro Hosono; Shu Kachi; Hiroko Terasaki; Yoshihiro Hotta; Shinsei Minoshima View Presentation 1322 - A0016. Allelic variation of visual pigments in capuchin monkeys, Sapajus spp Daniela M. Bonci; Maureen Neitz; Paulo Roney K. Goulart; Juliana G. Soares; Mario Fiorani; Olavo F. Galvão; Ricardo Gattass; Luiz Carlos L. Silveira; Dora F. Ventura View Presentation 1323 - A0017. Retinal gene expression in mice lacking cones and/or rods identifies genes potentially involved in human eye function and disease Richard J. Holt; Laurence Brown; Rachel Butler; Susan M. Downes; Stuart N. Peirson; Stephanie Halford View Presentation 1324 - A0018. Progressive Fundus Autofluorescence Patterns in Achromatopsia Abigail T. Fahim; Naheed W. Khan; Sarwar Zahid; Ira H. Schachar; Kari E. Branham; Susanne Kohl; Bernd Wissinger; Victor M. Elner; John R. Heckenlively; Kanishka T. Jayasundera View Presentation 1325 - A0019. Molecular modeling of functional domain of ABCA4: towards understanding the genotype-to-phenotype relationships in Stargardt’s disease Yuri V. Sergeev; Katherine L. Pogrebniak; Benedetto Falsini; Wadih M. Zein; Kerry Goetz; Jillian Huang; Crandall E. Peeler; Kanishka T. Jayasundera; Brian P. Brooks; Paul A. Sieving View Presentation 1326 - A0020. The frequency of 5 mutations in the ABCA4 gene in Russian patients with a clinical diagnosis of Stargardt disease / Fundus Flavimaculatus Maria Shurygina; Sergey Borzenok; Olga Khlebnikova; Oksana Nekrasova; Olga Kravchuk View Presentation 1327 - A0021. Visual Prognosis and Association Between Geno - and Phenotype in Families with ABCA4 Mutations Ulrika Kjellstrom; Sten Andreasson View Presentation 1328 - A0022. Complement Factor Y402H polymorphism is not associated with Stargardt’s Disease in Italian Patients Andrea Sodi; Ilaria Passerini; Vittoria Murro; Luca Boni; Giacomo Abbruzzese; Alba Miele; Matteo Giuntoli; Giulio Mecocci; Francesca Torricelli; Ugo Menchini View Presentation 1329 - A0023. SNRNP200 Mutations Account for 2% of Autosomal Dominant Retinitis Pigmentosa Lori S. Sullivan; Sara J. Bowne; Cheryl E. Avery; Dianna K. Wheaton; David G. Birch; Kari E. Branham; John R. Heckenlively; Stephen P. Daiger View Presentation 1330 - A0024. Impact of CHM Mutations at the mRNA level Markus N. Preising; Nayyir Alavi; Birgit Lorenz View Presentation 1331 - A0025. Genetic and clinical features of FEVR and Norrie disease Eisuke Arai; Takuro Fujimaki; Ai Miyazaki; Keiko Fujiki; Fumino Iwata; Takenori Inomata; Hiroyuki Kawano; Toshiyuki Yokoyama; Akihisa Okumura; Akira Murakami View Presentation 1332 - A0026. Presentation and Progression of the Ocular Manifestations of Methylmalonic Acidemia in Children Jacqueline K. Ng; Daniel J. Karr; Leah Reznick; Mark E. Pennesi View Presentation 1333 - A0027. Genotype-Phenotype correlations in patients with Basal Laminar Drusen and Systemic Associations Suman Pilli; Martin McKibbin; Clare Bailey; Sheila Pinto; Jesus Garcia-Fernandez; Helen L. Griffiths; Santiago Rodriguez de Cordoba; Andrew J. Lotery View Presentation 1334 - A0028. Novel mutations of the RS1 gene in a cohort of patients with retinoschisis Yang Li; Jieqiong Chen; Yanfan Ren; Xiaohui Zhang; Zhe Pan View Presentation 1335 - A0029. A knock- in mouse model for recessive RP-foveoschisis-optic disc drusen and nanophthamos syndrome due to a mutation in the Mfrp gene Bhubanananda Sahu; Venkata R. Chavali; John Suk; Rachel Poleman; Akhila Alapati; Bruno Maranhao; Monica M. Jablonski; Dirk-Uwe G. Bartsch; Radha Ayyagari View Presentation 1336 - A0030. Screening for Usher Syndrome in an established cochlear implant program: the merits of a collaborative paradigm Elise Heon; Ajoy Vincent; Joanne E. Sutherland; Megan Day; Blake C. Papsin; Sharon L. Cushing View Presentation 1337 - A0031. Tietz syndrome (albinism and congenital deafness): Description of a familiar case carrying a novel MITF gene mutation and associated with nanophthalmos Luz V. Cortés; Martin Guzman-Sanchez; Dalia C. Guadarrama; Juan C. Zenteno; Cristina Villanueva-Mendoza View Presentation 1338 - A0032. A novel COL2A1 nonsense mutation causes Stickler syndrome type I Mohamed M. Khafagy; Daniel F. Schorderet; Hana Abouzeid View Presentation 1339 - A0033. Ocular Manifestations and Genotype-Phenotype Correlations in a group of 12 patients with the Marfan Syndrome Marta Latasiewicz; Elena Milla; Christian Fontecilla; Aurora Sanchez View Presentation 1340 - A0034. Ocular development and axial length in the Bestrophinopathies Julie De Zaeytijd; Tine Sabbe; Elfride De Baere; Bart P. Leroy View Presentation 1341 - A0035. Comparison of human and murine ocular findings in the Knobloch syndrome caused by mutations in COL18A1 Behrad Y. Milani; Stephen H. Tsang; Irene H. Maumenee View Presentation 1342 - A0036. Jalili syndrome: retinal dystrophy and amelogenesis imperfecta: genotype-phenotype analysis in four new cases Christina Gerth-Kahlert; Britta Seebauer; Sandra Dold; Johannes Fleischhauer; Hubertus van Waes; Wolfgang Berger View Presentation 1343 - A0037. The RICO mouse – a novel model of dominant uveal coloboma Ramakrishna Alur; Felix I. Onojafe; Amalia Dutra; James Thomas; Marcus Fruttiger; William D. Richardson; Lorenzo Nichols; Peter F. Hitchcock; Brian P. Brooks; Sandra Pieke-Dahl View Presentation 1344 - A0038. Variable Phenotype & Retinal Abnormalities in Ectopia Lentis Et Pupillae Bart P. Leroy; Cathérine Boileau; Nadine Hanna View Presentation 1345 - A0039. Inositol 5-Phosphatases in Primary Cilia Formation in Lowe syndrome Yang Sun; Akhilesh Kumar; Michael Conwell; Jingyun Wang; Robert N. Weinreb; Na Luo View Presentation 1346 - A0040. Evidence of the role of ADAMTS18 in ocular development Aman Chandra; Gavin Arno; Panagiotis I. Sergouniotis; Arundhati Dev Borman; Andrew Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 62 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM R. Webster; Anthony T. Moore View Presentation 1347 - A0041. Allelic Heterogeneity Contributes to Variability in Ocular Dysgenesis, Myopathy, and Brain Malformations Caused by Col4a1 and Col4a2 Mutations Debbie S. Kuo; Cassandre Labelle-Dumais; Mao Mao; Marion Jeanne; William B. Kauffman ; Jennifer Allen; Jack Favor; Douglas B. Gould View Presentation 1348 - A0042. MIR184 c.57C>T mutation is responsible for congenital cataracts and corneal abnormalities in a five-generation family from Galicia, Spain Yelena Bykhovskaya; Kenneth W. Wright; Yaron S. Rabinowitz; Ana Laura C. Canedo View Presentation 1349 - A0043. Congenital Cataract Locus in a Seven Generation Family Sarah J. Garnai; Jeroen R. Huyghe; David M. Reed; Kathleen M. Scott; Michael Boehnke; Julia E. Richards; Robert Ritch; Hemant S. Pawar View Presentation 1350 - A0044. Crystal deposits in the anterior lens cortex in Bietti crystalline corneoretinal dystrophy and first report of chroidal neovascular membrane in patient affected with Bietti Veronika Vaclavik; Francis L. Munier; Daniel F. Schorderet; Viet H. Tran View Presentation 1351 - A0045. Molecular characterization in Mexican patients with anterior segment dysgenesis including primary congenital glaucoma, aniridia, Peters anomaly and Axenfeld-Rieger anomaly and syndrome Cristina Villanueva-Mendoza; Nancy Hernández-Martínez; Miguel A. Alcántara-Ortigoza; Omar Honerlage-Ceniceros; Ariadna González-Del Angel; Rehotbevely B. BarrientosRíos; Luz M. González-Huerta View Presentation 1352 - A0046. Functional characterization of a homozygous nonsense FOXE3 mutation that causes Peters anomaly in a consanguineous family Arif O. Khan; Shahid Y. Khan; Zhiwei Ma; Saleh Al-Mesfer; Shahira Al Turkmani; Sheikh Riazuddin; Walter Stark; James F. Hejtmancik; John D. Gottsch; S. Amer Riazuddin View Presentation 1353 - A0047. Mutant LTBP-2 proteins lack secretion ability and fibrillin-1 binding activity Tomoya O. Akama; Yusuke Fujikawa; Tadashi Inoue; Tomoyuki Nakamura View Presentation 1354 - A0048. Multiplex Ligation-dependent Probe Amplification (MLPA) for detection of large deletions in CYP1B1 in congenital glaucoma patients from the US Keri Allen; Maria Janessian; Kevin Linkroum; Wael Abdrabou; Janey L. Wiggs View Presentation 1355 - A0049. Clinical features of OPA1-related optic neuropathy: a retrospective case series Eric Gaier; Phillip Skidd; Maria Janessian; Simmons Lessell; Dean Cestari; Joseph F. Rizzo; Janey L. Wiggs View Presentation 1356 - A0050. New candidate genes for inherited optic atrophy Cecile Delettre; Maxime Hebrard; Francois Halloy; agathe roubertie; Christian P. Hamel; Guy Lenaers View Presentation 1357 - A0051. Pan-American MtDNA haplogroups in LHON patients Pablo T. Romero; Mark A. Slabaugh; Verónica Fernández; Nicolás Seleme; Patricio Pezo; Luisa M. Herrera; Mauricio Moraga View Presentation 1358 - A0052. Prenatal Molecular Diagnosis of Oculocutaneous Albinism (OCA) in a Large Cohort of Israeli Families Anat Blumenfeld; Dalia Eli; Idit Bejarano-Achache ; Efrat Shemesh; Irene I. Anteby; Claudia Yahalom; Ada Rosenmann View Presentation 1359 - A0053. Molecular diagnostic testing by eyeGENE®: Analysis of patients with hereditary maculopathy and/or Cone Rod Dystrophy John Suk; Akhila Alapati; Kerry Goetz; Santa J. Tumminia; Radha Ayyagari View Presentation 1360 - A0054. VON HIPPEL LINDAU: 3q134X MUTATION FINDING Juan Pablo Davila; alejandra valladares; Thamar Gomez-Villegas; Araceli Rojas-Diaz View Presentation 228. AMD: Inherited Retinal Degenerations and Mechanisms of Disease View Session Details Moderator(s): Mina Chung (Flaum Eye Inst Univ of Rochester) and Joe Hollyfield (Cole Eye Institute, Cleveland Clinic) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 1361 - A0055. AAV-mediated treatment of retinal degeneration in the Nrf2 knockout mouse Katharine J. Liang; Kenton T. Woodard; Richard Samulski View Presentation 1362 - A0056. Retinal Histopathology in Eyes from Patients with Autosomal Recessive Retinitis Pigmentosa Caused by EYS Mutations Gayle J. Pauer; Vera L. Bonilha; Mary E. Rayborn; Brent A. Bell; Meghan J. Marino; Craig D. Beight; John Chiang; Elias I. Traboulsi; Stephanie A. Hagstrom; Joe G. Hollyfield View Presentation 1363 - A0057. Retinal Histopathology in Eyes from a Patient with Stargardt Disease Caused by Compound Heterozygous ABCA4 Mutations Joe G. Hollyfield; Vera L. Bonilha; Mary E. Rayborn; Brent A. Bell; Meghan J. Marino; Gerald A. Fishman View Presentation 1364 - A0058. Retinal Histopathology in Eyes from Patients with Autosomal Dominant Retinitis Pigmentosa caused by Rhodopsin Mutations Mary E. Rayborn; Vera L. Bonilha; Brent A. Bell; Xiaoping Yang; Meghan J. Marino; Gayle J. Pauer; Craig D. Beight; Elias I. Traboulsi; Stephanie A. Hagstrom; Joe G. Hollyfield View Presentation 1365 - A0059. Mitochondrial retinal dystrophy: genetic background, clinical classification, and systemic associations Camiel J. Boon; Paul de Laat; Mirian Janssen; Jan A. Smeitink; Jan E. Keunen View Presentation 1366 - A0060. Retinal Lamination Patterns in Macular Retinoschisis Hilary S. Brader; Brian VanderBeek; Albert M. Maguire; Jason Ruggiero; Paul J. Tapino; Alexander J. Brucker; Tomas S. Aleman View Presentation 1367 - A0061. Interocular Difference and Interocular Correlation in Visual Acuity and Focal Macular Electroretinogram in Stargardt Disease Patients with an ABCA4 Genotype Dario Marangoni; Marco Piccardi; Angelo M. Minnella; Matteo Bertelli; Dario Degiorgio; Monia Zuntini; Silvia Bisti; Benedetto Falsini View Presentation 1368 - A0062. Late-Onset Retinal Macular Degeneration: refining the phenotype Shyamanga Borooah; Vasileios T. Papastavrou; Andrew Browning; Baljean Dhillon View Presentation 1369 - A0063. Analysis of Phenotype in Mouse Models of Stargardt Disease for Identification of Modifying Genes Benjamin Bakall; Megan J. Riker; Prithviraj P. Patankar; Rebecca M. Johnston; Dianna Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 63 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM K. Brack; Janet Riley; Robert F. Mullins; Michael G. Anderson; Edwin M. Stone View Presentation 1370 - A0064. Microperimetric analysis for investigation of ABCA4-related Stardgardt’s disease progression Marcella Attanasio; Settimio Rossi; Francesco Testa; Paolo Melillo; Valentina Di Iorio; Anna Nesti; Francesca Simonelli View Presentation 1371 - A0065. Rule of multifocal electroretinogram in follow-up of ABCA4-related Stardgardt’s disease Ada Orrico; Francesco Testa; Settimio Rossi; Paolo Melillo; Antonella de Benedictis; Michele Della Corte; Francesca Simonelli View Presentation 1372 - A0066. Adaptive Optics Scanning Laser Ophthalmoscopy Demonstrates Reduced Foveal Cone Density in Pattern Dystrophy Xiaofei Wang; Hongxin Song; Margaret A. Folwell; Lisa R. Latchney; Mina M. Chung View Presentation 1373 - A0067. PARP1 Knock-Out Mice Prevents N-methyl-N-nitrosourea-induced Photoreceptor Degeneration Xinrong Zhou; Tomohiro Masuda; Zhiyong Yang; Gillian C. Shaw; Cynthia A. Berlinicke; Shaida A. Andrabi; Yingfei Wang; Valina L. Dawson; Ted M. Dawson; Donald J. Zack View Presentation 1374 - A0068. The Role of Phospholipid Transfer Protein (PLTP) in Lipoprotein Metabolism in the Retina Amirfarbod Yazdanyar; Xian-Cheng Jiang; Douglas R. Lazzaro; William J. Brunken View Presentation 1375 - A0069. The Role of Microglia in Retinal Degeneration of Mice with Defective NR2E3 Gene Nan-Kai Wang; Chi-Chun Lai; Chi-Hsiu Liu; Lung-Kun Yeh; Takayuki Nagasaki; Stephen H. Tsang View Presentation 1376 - A0070. Heme oxygenase-1 gene therapy in a mice model of atrophic age-related macular degeneration Ming-Hui Sun; Yeou-Ping Tsao; Kuan-Jen Chen View Presentation 1377 - A0071. CD59a deficiency leads to increased age-related subretinal macrophage accumulation and elevated local C3 expression in the RPE/choroid complex of aged mice Philipp Herrmann; Jill Cowing; Ulrich F. Luhmann; Robin R. Ali View Presentation 1378 - A0072. Regulation of the cholesterol efflux transporters ABCA1/ABCG1 in retina in hemochromatosis and by the endogenous iron chelator 2,5-dihydroxybenzoic acid Sudha Ananth; Brooke R. Baldowski; Pamela M. Martin; Sylvia B. Smith; Vadivel Ganapathy View Presentation 1379 - A0073. Regulation of the cholesterol efflux transporter ABCA1 by the niacin receptor GPR109A: potential relevance to drusen biogenesis and inflammation in agerelated macular degeneration (AMD) Wanwisa Promsote; Rajalakshmi Veeranan-Karmegam; Sudha Ananth; Vadivel Ganapathy; Pamela M. Martin View Presentation 1380 - A0074. Comparison of autophagy in hfRPE and ARPE-19 as two different models to study the pathogenesis of AMD Haben F. Kefella; Shabnam Pakneshan; Tave A. van Zyl; Ron A. Adelman; Lawrence J. Rizzolo View Presentation 1381 - A0075. Age-Associated Changes of mTOR Signaling in The Retinal Pigment Epithelium Bo Yu; Zhen-Yang Zhao; Yiqin Zuo; Pei Xu; Paul Sternberg; Yan Chen View Presentation 1382 - A0076. Vectorial release of matrix metalloproteinase enzymes from porcine RPE in explant culture following nanosecond laser exposure Ling Zhi Heng; Ali A. Hussain; Sobha Sivaprasad; Robin D. Hamilton; John Marshall View Presentation 229. Ocular Nanotherapy, Nanoparticles, and Gene Therapy Moderator(s): Jose Sahel (Institut de la Vision) and Alexander Ljubimov (Cedars-Sinai Medical Center) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 1383 - B0001. Use of Polymeric Scaffolds as Extracellular Matrix Substitutes for Conjunctival Epithelial Repair Thomas Storr-Paulsen; Matthew Fullana; Annie L. Wang; Dimitrios Karamichos; Tor P. Utheim; Marie A. Shatos; Jesper Hjortdal; Gary E. Wnek; Darlene A. Dartt View Presentation 1384 - B0002. Protein-Based Retinal Implant Nicole L. Wagner; Jordan A. Greco; Robert R. Birge View Presentation 1385 - B0003. Kinetics of dexamethasone cyclodextrin nanoparticle suspension eye drops in tear fluid Gauti Johannesson; Maria D. Moya-Ortega; Gudrun M. Asgrimsdottir; Thorsteinn Loftsson; Einar Stefánsson View Presentation 1386 - B0004. Engineering a biocompatible cell carrier with nanofeatured topography for retinal pigment epithelium transplantation Zengping Liu; Na Yu; Frank G. Holz; Fang Yang; Boris V. Stanzel View Presentation 1387 - B0005. Proliferation of porcine conjunctival fibroblasts in fibrin-based scaffolds using alamar blue assay Ana Fernández ; Jennifer Ramos; Marta López; Patricia Pérez; Elizabeth Santín; Leire Llorente; Yolanda Diebold; F. Javier Iglesias View Presentation 1388 - B0006. Novel pentablock copolymers as a nanotechnology platform for controlled ocular delivery of proteins Sulabh Patel; Gyan Mishra; Viral Tamboli; Ashim K. Mitra View Presentation 1389 - B0007. Acuboost™: Enhancing the maximum acuity of the Argus II Retinal Prosthesis System Jose A. Sahel; Saddek Mohand-Said; Paulo E. Stanga; Avi Caspi; Robert J. Greenberg View Presentation 1390 - B0008. Lab-on-a-tube for in situ ocular bioassays: continuous glucometry in tears Andrew W. Browne; Chunyan Li View Presentation 1391 - B0009. The effect of retinoic acid to induce one of the perioculer neural crest Motokazu Tsujikawa; Erika Kimura; Yoshinori Oie; Takeshi Soma; Susumu Hara; Ryuhei Hayashi; Shin Hatou; Satoru Yoshida; Shigeto Shimmura; Kohji Nishida View Presentation 1392 - B0010. Tissue Engineered Model of the Outer Neural Retina and Retinal Pigment Epithelium Karl E. Kador; Enrique Salero; Kristina R. Russano; Lung W. Lau; Jeffrey L. Goldberg View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 64 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 1393 - B0011. Regenerative response of optic nerve axons while using a specifically designed hydrogel Arieh S. Solomon; Anat Nitzan; Moran Aviv; Shmuel Einav; Ehud Gazit; Zvi Nevo View Presentation 1394 - B0012. Biocompatibility of helicoidal multi-lamellar features of RGD-functionalized silk biomaterials for tissue engineering cornea Liqiang Wang; Huiling Guo; Ying Dong; Gaiping Du; Yifei Huang; Liang Jia View Presentation 1395 - B0013. A Novel Fish Scale Derived Scaffold for Ocular Reconstruction Tine Possemiers; Nadia Zakaria; Veerle Van Gerwen; Shih-Cheng Chen; Horng J. Lai; Chien C. Lin; Marie-José B. Tassignon View Presentation 1396 - B0014. Ascl1 reprograms Müller glia into functional retinal neurons Julia Pollak; Matthew Wilken; Yumi Ueki; Kristin E. Cox; Russell J. Taylor; Thomas A. Reh View Presentation 1397 - B0015. Chitosan-Gelatin Biopolymers as Carrier Substrata for Limbal Epithelial Stem Cells Teresa Nieto-Miguel; Ana de la Mata; Marina López-Paniagua; Sara Galindo; María R. Aguilar; Luis García-Fernández; Blanca Vazquez; Julio San Román; Rosa M. Corrales; Margarita Calonge View Presentation 1398 - B0016. Different aligned multiwalled carbon nanotubes an their effects on cell viability and growth charactaristics Claudia Etzkorn; Sandra Johnen; Frank Meissner; Ingolf Endler; Peter Walter View Presentation 1399 - B0017. Keratin-chitosan membranes as scaffold for tissue engineering of human cornea ALVARO MEANA; Natalia Vázquez; Manuel Chacón; Yolanda Menéndez-Menéndez; Amaia Ferrero-Gutierrez; Jesus Merayo-Lloves View Presentation 1400 - B0018. Restoration of light sensitivity to blind mice with red-shifted chemical photoswitches Ivan Tochitsky; Aleksandra Polosukhina; Andrew Noblet; Dirk Trauner; Richard H. Kramer View Presentation 1401 - B0019. In Vivo Functional Comparison of Polarized and Non-polarized hESCRPE Cells Transplantation in RCS Rats Laura Liu; Biju B. Thomas; Ramiro Ribeiro; Alejandra Gonzalez-Calle; Danhong Zhu; Padmaja B. Thomas; Keng-Hung Lin; Yuntao Hu; David R. Hinton; Mark S. Humayun View Presentation 1402 - B0020. Tissue Engineering of a Human Choroid Containing a Vascular Network and Melanocytes Stephanie Proulx; Marie Guimond; Olivier Rochette-Drouin; Solange Landreville View Presentation 1403 - B0021. A polymer-based interface restores light sensitivity in rat blind retinas Maurizio Mete; Grazia Pertile; Diego Ghezzi; Maria Rosa Antognazza; Rita Maccarone; Erica Lanzarini; Nicola Martino; Silvia Bisti; Guglielmo Lanzani; Fabio Benfenati View Presentation 1404 - B0022. Reconstruction of the ocular surface with adipose-derived stem cells (ASCs) almudena del hierro; Ana Boto; Ignacio García Gomez; Mariano García-Arranz; Alfredo Insausti García; Félix Armada View Presentation 1405 - B0023. Development of a Microemulsion Library for Drug Screening Drew Wassel; Fadee Mondalek; Alexander B. Quiambao; Rafal Farjo View Presentation 1406 - B0024. Early data on the effect of continuous positive airway pressure (CPAP) on intraocular pressure (IOP) changes measured by a contact lens sensor (CLS) in patients with obstructive sleep apnea syndrome (OSAS) with and without primary open-angle glaucoma (POAG) Jessica V. Jasien; Rene Goedkoop; Cinthi Pillai; Sonja Simon-Zoula; Robert Ritch View Presentation 1407 - B0025. Optimized cell-handling of human embryonic stem cells in the differentiation of photoreceptor precursor cells Christopher R. Laver; Anat Yanai; Aaron Joe; Ishaq Ahmed viringipurampeer; Xia Wang; Andrew Metcalfe; Cheryl Y. Gregory-Evans; Kevin Gregory-Evans View Presentation 1408 - B0026. Mesenchymal stem cell based ex vivo gene therapy provides enhanced neuroprotection in X-linked retinoschisis mouse model AMA E. Bashar; Andrew Metcalfe; Ishaq Ahmed viringipurampeer; Cheryl Y. GregoryEvans; Orson L. Moritz; Kevin Gregory-Evans View Presentation 1409 - B0027. Histological correlation of superior collicus response to light preserved by transplantation of hESC derived RPE monolayer in RCS rats Biju B. Thomas; Padmaja B. Thomas; Laura Liu; Yuntao Hu; Danhong Zhu; Dennis O. Clegg; David R. Hinton; Mark S. Humayun View Presentation 1410 - B0028. Generation of engineered human corneal lenticule with epithelium for selective allograft MAN-IL HUH; Eun-Jin Yeo; Jun Hun Lee; Hong-Kyun Kim View Presentation 230. Optic Nerve: Mechanisms of Damage and Neuroprotection in Animal and in Vitro Models Moderator(s): Kenneth Shindler (Univ of Pennsylvania, Scheie Eye Inst) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 1411 - B0029. Molecular and histological changes in the dLGN and cortices and their time-course secondary to trans-synaptic degeneration after optic nerve injury Yuyi You; Vivek Kumar Gupta; Alexander Klistorner; Stuart Graham View Presentation 1412 - B0030. Nmnat3 inhibits up-regulation of p62 in high IOP-induced optic nerve degeneration Yasushi Kitaoka; Yasunari Munemasa; Kaori Kojima; Satoki Ueno View Presentation 1413 - B0031. SIRT1 Delays RGC Loss Following Optic Nerve Crush By Reducing Oxidative Stress ling zuo; Vivian Lee; Reas S. Khan; Kimberly E. Dine; Wen Wu; Kenneth S. Shindler View Presentation 1414 - B0032. Dexras1 Mediates Retinal Ganglion Cell Loss Induced by NMDA Excitotoxicity Reas S. Khan; Yong Chen; Alyssa Cwanger; Ying Song; Joshua L. Dunaief; Sangwon F. Kim; Kenneth S. Shindler View Presentation 1415 - B0033. Loss of the E3 ubiquitin ligase Phr1 is Neuroprotective in Retinal Ganglion Cells Rachel Lamb; Susan M. Culican View Presentation 1416 - B0034. Impact of plasma from patients with neuromyelitis optica spectrum Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 65 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Withdrawn 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM disorders on the optic degeneration in rats Yoshiko Matsumoto; Akiyasu Kanamori; Makoto Nakamura; Ichiro Nakashima; Akira Negi View Presentation 1417 - B0035. Retinal ganglion cell loss and inflammatory demyelination in an experimental autoimmune encephalomyelitis model Lioba Horstmann; Heiko Schmid; Florian Kurschus; Ari Waisman; Burkhard H. Dick; Stephanie C. Joachim View Presentation 1418 - B0036. Potential roles of the microglia and mononuclear cells interaction in experimental autoimmune optic neuritis Ryusaku Matsuda; Takeshi Kezuka; Chiharu Nishiyama; Yoshihiko Usui; Yoshimichi Matsunaga; Naoyuki Yamakawa; Ko Okumura; Hiroshi Goto View Presentation 1419 - B0037. Induction of autophagy prevents increase of p-PS1 in TNF-induced optic nerve axonal degeneration Kaori Kojima; Yasushi Kitaoka; Yasunari Munemasa; Satoki Ueno View Presentation 1420 - B0038. Neuroprotective effects of recombinant human granulocyte colonystimulationg factor (G-CSF) in a rat model of anterior ischemic optic neuropathy (rAION) Rong-Kung Tsai View Presentation 1421 - B0039. Syntaphilin is expressed in astrocytes in optic nerve and is down regulated in optic nerve after axonal injury Akiko Miki; Akiyasu Kanamori; Makoto Nakamura; Yoshiko Matsumoto; Akira Negi View Presentation 1422 - B0040. Time course of oligodendrocyte death after rAION in Sprague Dawley rats Zara Mehrabyan; Yan Guo; Steven L. Bernstein View Presentation 1423 - B0041. Post-ischemic Glial Response in A Rodent Model of Non-Arteritic Anterior Ischemic Optic Neuropathy Shin Hae Park; Jun-Sub Choi; Choun-Ki Joo View Presentation 1424 - B0042. Peripapillary Edema Is Associated with Nerve Fiber Layer Atrophy in a Primate Model of Nonarteritic Anterior Ischemic Optic Neuropathy Mary A. Johnson; Neil R. Miller; Steven L. Bernstein View Presentation 1425 - B0043. Severe Impairment of Axonal Transport in Acute Experimental Anterior Ischemic Optic Neuropathy Jeffrey Ma; Madison Stanford; Ali Shariati; Gun Ho Lee; Yaping J. Liao View Presentation 1426 - B0044. TLR4 knock-out mice are resistant to optic nerve crush damage Nitza Goldenberg-Cohen; Dana Morzaev; Shirel R. Weiss; Edith Hochhauser View Presentation 1427 - B0045. Optic nerve and inner retina damage after repeated mild traumatic brain injury in a mouse model Radouil T. Tzekov; Austin Ferro; Benoit Mouzon; Davida Biggins; Robert C. Spinelli; Myles Mullan; Michael Mullan; Fiona Crawford View Presentation 1428 - B0046. Augmented Reality Modification of Image Guided Endoscopic Orbital Surgery Technique Louise A. Mawn; Michael P. DeLisi; Robert L. Galloway View Presentation 1429 - B0047. Evaluation of pharmacological approaches to downregulation of pathogenic gliotic response in the eye Pavel Iserovich View Presentation 1430 - B0048. Characterisation of Olfactory Mucosa for Olfactory Ensheathing Cell therapy in optic nerve diseases Maayke M. Kuijten; Annegret Dahlmann-Noor; Steve Brocchini; Peng T. Khaw View Presentation 231. Glaucoma and Optic Neuropathies Imaging Moderator(s): Ching-Yu Cheng (National University of Singapore) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 1431 - B0158. Optical Coherence Tomography of the Optic Nerve: Comparison Between Multiple Sclerosis and Neuromyelitis Optica Lucas Daniel A. Fernandes; Phelipe A. Paixao; Lorena B. Botelho Vergara; Juliana F. Araujo; Eliza Maria C. Lacerda; Givago S. Souza; Hideraldo Luis Souza Cabeça; Alexandre A. Rosa; Luiz Carlos L. Silveira View Presentation 1432 - B0159. Multimodal retinal imaging in multiple sclerosis with and without optic neuritis Elisabetta Pilotto; Paolo Gallo; Francesca Guidolin; Enrica Convento; Matteo Atzori; Marco Puthenparampil; Raffaele Parrozzani; Edoardo Midena View Presentation 1433 - B0160. The assessment of retinal optical properties in multiple sclerosis Gabor Mark Somfai; Erika Tatrai; Boglárka E. Varga; Kornélia Lenke Laurik; Magdolna Simó; Delia DeBuc View Presentation 1434 - B0161. In vivo microscopic inner retinal phenotypes of retinal and neurologic disease Drew H. Scoles; Robert F. Cooper; Adam M. Dubis; Brian P. Higgins; Joseph Carroll; Alfredo Dubra View Presentation 1435 - B0162. Is retinal optical coherence tomography an imaging biomarker for Parkinson disease? Francisco J. Ascaso; Beatriz Jimenez; Javier López del Val; Isabel Pinilla Lozano; Diana Perez-Garcia; Juan Ibanez-Alperte; José A. Cristóbal View Presentation 1436 - B0163. Retinal and peripapillary nerve fiber layer thickness in eyes with thyroidassociated ophthalmopathy Meira Neudorfer; Sharon Blum; Anat Kesler; David Varssano; Igal Leibovitch View Presentation 1437 - B0164. The Effect of Media Opacities on Retinal Nerve Fiber Layer and Macular Inner Retinal Layer Measurements with Spectral Domain Optical Coherence Tomography Stanley Darma; Pauline H. Kok; Michael D. Abramoff; Thomas J. Van Den Berg; Frank D. Verbraak View Presentation 1438 - B0165. Ganglion Cell Complex and Retinal Nerve Fiber Layer Measurements in Patients with Alzheimer’s Disease and Mild Cognitive Impairment Nataliya Semenova; Vladimir Akopyan; Ekaterina Gurova View Presentation 1439 - B0166. Optical Coherence Tomography imaging of Eyes with Optic Nerve Head Drusen Taku Sato; Sarah Mrejen; Richard F. Spaide View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 66 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 1440 - B0167. Intraocular Pressure (IOP) Elevation Reduces Schlemm’s Canal CrossSectional Area (SC-CSA) in Living Human Eyes Larry Kagemann; Bo Wang; Gadi Wollstein; Hiroshi Ishikawa; Zach Nadler; Jessica E. Nevins; Ian A. Sigal; Jonathan L. Grimm; Richard A. Bilonick; Joel S. Schuman View Presentation 1441 - B0168. Enhanced depth optical coherence tomography imaging of the optic nerve canal in central retinal vein occlusion Hamid Hosseini; David Rivera; Gad Heilweil; Jean-Pierre Hubschman; Irena Tsui; Steven D. Schwartz View Presentation 1442 - B0169. A Comparison of Methods for Correcting Ocular Magnification to Reduce the Variance of Normal Retinal Nerve Fiber Layer Thickness Measurements Alyssa C. Ehrlich; David W. Rhee; Ali S. Raza; Tobias Duncker; Jonathan P. Greenberg; Vivienne C. Greenstein; Donald C. Hood View Presentation 1443 - B0170. Correlation between Visual Field Defects and Perifoveal Ganglion Cells Layer Thickness in Eyes Affected by Optic Neuropathy Andrea Coppe; Giuliana Lapucci View Presentation 1444 - B0171. Comparative assessment for the ability of Cirrus, RTVue and 3D OCT to diagnose glaucoma with high myopia Akiyasu Kanamori; Azusa Akashi; Makoto Nakamura; Masashi Fujihara; Yuko Yamada; Akira Negi View Presentation 1445 - B0172. iVue® iWellnessExam™ Retains Highs Sensitivity & Specificity Among Novice Reviewers Samantha Slotnick; Daniel Epshtein; Catherine Awad; Sanjeev Nath; Jerome Sherman View Presentation 1446 - B0173. Analyzing Shape Parameterization of SD-OCT Optic Nerve Head Images in High Myopes as a Predictor of Visual Field Defects Sonny Sabhlok; Daniel Russakoff; Tessa Johung; Jonathan D. Oakley; Felix Li; Kuldev Singh; Robert Chang View Presentation 1447 - B0174. Repeatability and Reproducibility of iVue FD-OCT System Yuanmu Deng; Kelly A. Soules; Danny Leung; Wenjing Li; Ben K. Jang; Qienyuan Zhou View Presentation 1448 - B0175. Scanning Laser Polarimetry as a Complement to Optical Coherence Tomography in Multiple Sclerosis Jessica E. Chan; Daniel Feller; Steven L. Galetta; Laura Balcer View Presentation 1449 - B0176. Influence of Automated Disc Margin Determination on Stratus OCT Optic Nerve Head Measurements Ivan M. Tavares; Andre S. Camargo; Flavio E. Hirai; Luiz Alberto S. Melo View Presentation 1450 - B0177. Correction of the Retinal Angle in SD-OCT of Glaucomatous Eyes Provides Better Reproducibility of Optic Nerve Head Parameters Kyungmoo Lee; Young H. Kwon; Michael D. Abramoff; Mona K. Garvin; Milan Sonka View Presentation 1451 - B0178. Imaging retinal nerve fiber loss in glaucoma using adaptive optics scanning laser ophthalmoscopy Gang Huang; Thomas Gast; Ting Luo; Toco Y. Chui; William H. Swanson; Victor Malinovsky; Stephen A. Burns View Presentation 1452 - B0179. Imaging of optic nerve head pore structure with motion corrected deeply penetrating OCT using tracking SLO Kari V. Vienola; Boy Braaf; Christy K. Sheehy; Qiang Yang; Pavan Tiruveedhula; David W. Arathorn; Johannes F. de Boer; Austin Roorda View Presentation 1453 - B0180. Ocular Biometries Using Spectral Domain Optical Coherence Tomography in Children with Large Cupping Ungsoo Kim; Jong Jin Jung; Seung-Hee Baek View Presentation 1454 - B0181. Indian Family Angle Closure Evaluation Study – Comparison of IridotomyAssociated Anatomic Changes in Angle Closure Suspects and Patients with Either Primary Angle Closure or Primary Angle Closure Glaucoma Rengaraj Venkatesh; Pradeep Y. Ramulu; Srinivasan Kavitha; PALANISWAMY KRISHNAMURTHY; David S. Friedman; Harry Quigley View Presentation 1455 - B0182. Spectral Domain OCT in Experimental Glaucoma Carol A. Rasmussen; Kimberly B. McIntyre; Anne K. Goulding; Chad D. Busse; Jennifer J. Szurka; Amanda L. Harvey; James N. Ver Hoeve; Christopher J. Murphy; Brian J. Christian; T Michael Nork View Presentation 1456 - B0183. Choroidal thickness in glaucoma and diabetic patients with good visual acuity Gloria Wu; Anh Tran; Steven Young; Eric Chen; Vinna Nam; Agastya Gupta; Jane Xu; Susan M. Hailpern View Presentation 1457 - B0184. Diagnostic Validity of Macular Ganglion Cell-Inner Plexiform Layer Thickness Deviation Map Using Spectral Domain Optical Coherence Tomography in Preperimetric and Early Glaucoma Sang Woo Park; Jung-Han Choi View Presentation 1458 - B0185. Investigation of the retinal thickness using Spectralis OCT® reveals a significant decrease after short time elevation of IOP Julia Teister; Oliver W. Gramlich; Theresa Lueckner; Maren Kriechbaum; Norbert Pfeiffer; Franz H. Grus View Presentation 1459 - B0186. Relationship between Retinal Vascular Parameters and Optic Nerve/ Ganglion Cell-Inner Plexiform Layer Parameters in Non-Glaucomatous Eyes Yih Chung Tham; Tien Y. Wong; Tin Aung; Ching-Yu Cheng; Carol Y. Cheung View Presentation 1460 - B0187. retinal nerve fiber layer defect and its associations in Adult Chinese Population Ya Xing Wang; Liang ZhAO; Jost B. Jonas; Liang Xu View Presentation 1461 - B0188. The Use of Handheld Optical Coherence Tomography in Urban Community Eye Screening James Lin; Priya Patel; Ben Szirth; Albert S. Khouri View Presentation 1462 - B0189. Comparison of coupled level sets and graph cuts for retinal layer segmentation in optical coherence tomography Jelena Novosel; Marvin Ostermann; Gijs Thepass; Hans G. Lemij; Koenraad A. Vermeer; Lucas J. van Vliet View Presentation 1463 - B0190. Logistic Regression Model for Principal Factor Analysis Combining Spectral Domain OCT Structural Parameters for Detection of Early Glaucoma Jean-Claude Mwanza; Joshua Warren; Donald L. Budenz View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 67 sur 222 232. Advancement in Imaging Technologies Moderator(s): Christoph Hitzenberger (Medical University of Vienna) and John Werner (Univ of California Davis Med Ctr) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Withdrawn 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 1464 - B0191. Structured illumination ophthalmoscope for high-resolution fluorescence imaging of retinal pigment epithelium Stefan Dithmar; Gerrit Best; Sabrina Rossberger; Thomas Ach; Stefanie Pollithy; Christoph Cremer View Presentation 1465 - B0192. Low-cost 3D Retinal Imaging using Structured Illumination Steve Gruppetta; Sabah Chetty View Presentation 1466 - B0193. Spectral OCT with novel speckle reduction technique for evaluation of the healing process after PRK and transepithelial PRK Maciej Wojtkowski; Bartlomiej J. Kaluzny; Danuta Bukowska; Maciej Szkulmowski View Presentation 1467 - B0194. Phase retardation changes of Henle’s fiber layer associated with aging Qiang Wang; Barry Cense; Omer P. Kocaoglu; Zhuolin Liu; Donald T. Miller View Presentation 1468 - B0195. Phase Retardation Asymmetry Associated with the Henle Fiber Layer in Normal Aging Dean A. VanNasdale; Ann E. Elsner; Christopher A. Clark; Stephen A. Burns View Presentation 1469 - B0196. Feasability of ultrawide-field retinal-shape measurement with MHz-OCT Wolfgang Wieser; Thomas Klein; Aljoscha S. Neubauer; Lukas Reznicek; Anselm Kampik; Robert Huber View Presentation 1470 - B0197. MultiImaging Using the Ultra Widefield Retinal Imaging Device for Fundus Screening Satoshi Ishiko; Hiroyuki Kagokawa; Akira Takamiya; Eiichi Sato; Kazuhiro Sugawara; Akitoshi Yoshida View Presentation 1471 - B0198. Characteristics of the Retinal Pigment Epithelium in Patients with Albinism using Wide-field Polarization-sensitive Optical Coherence Tomography Christopher Schuetze; Matthias Bolz; Markus Ritter; Robert Blum; Stefan Zotter; Bernhard Baumann; Michael Pircher; Erich Gotzinger; Christoph K. Hitzenberger; Ursula Schmidt-Erfurth View Presentation 1472. In Vivo Phase Retardation Measurements of Deposits in Bruch’s Membrane with Polarization-Sensitive Optical Coherence Tomography Barry Cense; Qiang Wang; Donald T. Miller; Joel A. Papay; Ann E. Elsner View Presentation 1473 - B0200. Analysis of partial and complete sparing of the Fovea in patients with Geograpic Atrophy by Polarization-Sensitive Optical Coherence Tomography Ramzi G. Sayegh; Stefan Zotter; Philipp K. Roberts; Matthias Bolz; Christopher G. Kiss; Magdalena Baratsits; Bernhard Baumann; Michael Pircher; Christoph K. Hitzenberger; Ursula Schmidt-Erfurth View Presentation 1474 - B0201. Investigation of the Choroid-Sclera Interface and Choroidal Thickness in 3D Polarization Sensitive OCT Images of the Human Eye Teresa Torzicky; Stefan Zotter; Michael Pircher; Bernhard Baumann; Christoph K. Hitzenberger View Presentation 1475 - B0202. Polarization Sensitive Optical Coherence Tomography with Retinal Tracking and Frame averaging Mitsuro Sugita; Stefan Zotter; Michael Pircher; Tomoyuki Makihira; Kenichi Saito; Nobuhiro Tomatsu; Christoph K. Hitzenberger View Presentation 1476 - B0203. Characterization of Stargardt disease using polarisation-sensitive spectral-domain optical coherence tomography and fundus autofluorescence imaging Markus Ritter; Stefan Zotter; Gabor Deak; Michael Pircher; Stefan Sacu; Christoph K. Hitzenberger; Ursula Schmidt-Erfurth View Presentation 1477 - B0204. Characteristic findings of retinitis pigmentosa in polarization sensitive optical coherence tomography Karin Kofler; Matthias Bolz; Bernhard Baumann; Stefan Zotter; Ferdinand G. Schlanitz; Philipp K. Roberts; Michael Pircher; Markus Ritter; Christoph K. Hitzenberger; Ursula Schmidt-Erfurth View Presentation 1478 - B0205. Cross polarization kit to enhance slit lamp fundoscopy Ken Tran; Thomas A. Mendel; Kristina Holbrook; Paul A. Yates View Presentation 1479 - B0206. Retinal and choroidal imaging with 870 nm spectral domain OCT compared to 1050 nm spectral domain OCT, with and without enhanced depth imaging Elizabeth Verner-Cole; John P. Campbell; Thomas S. Hwang; Michael L. Klein; Steven Bailey View Presentation 1480 - B0207. Choroidal imaging in gas-filled eye using swept source optical coherence tomography Ichiro Maruko; Yukinori Sugano; Hiroshi Oyamada; Tetsuju Sekiryu; Tomohiro Iida; Masahiro Akiba View Presentation 1481 - B0208. En Face Visualization of the Retinal Pigment Epithelium and Choroid in Chorioretinal Diseases using Swept-Source Optical Coherence Tomography Kathrin J. Mohler; Daniela Ferrara; Mehreen Adhi; Jonathan J. Liu; Ireneusz Grulkowski; Martin F. Kraus; Chen D. Lu; Joachim M. Hornegger; Jay S. Duker; James G. Fujimoto View Presentation 1482 - B0209. Swept source optical coherence tomography in eyes with macular hemorrhage Hiroshi Oyamada; Ichiro Maruko; Yukinori Sugano; Tetsuju Sekiryu; Tomohiro Iida View Presentation 1483 - B0210. Measurement of light reflection and scatter from eyes Mikhail Levin; Michael A. Campos; Anthony Dennison; Patrick De Guzman; Alireza Malek Tabrizi ; Hong Fu View Presentation 1484 - B0211. Functional Optical Coherence Tomography with a Commercial Device – A Pilot Study Michel M. Teussink; Mark J J P van Grinsven; Ramon A. van Huet; Barry Cense; Carel B. Hoyng; B. Jeroen Klevering; Thomas Theelen View Presentation 1485 - B0212. Focused ion beam sectioning retinal pigment epithelium cells Po-Kang Lin; Chieh-Hsiung Kuan View Presentation 1486 - B0213. Characterization of lipids in human meibomian gland using coherent Raman scattering microscopy Jeffrey Suhalim; Yilu Xie; Jeremiah Tao; Donald J. Brown; James V. Jester; Eric Potma View Presentation 1487 - B0214. Handheld MEMS-based Optical Coherence Tomography in Anterior and Posterior Segment Diagnosis Samir I. Sayegh; Jessica N. Taibl; Woongyu Jung; Daniel McCormick; Ryan Shelton; Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 68 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Ryan Nolan; Stephen A. Boppart View Presentation 1488 - B0215. Handheld Combined SLO/OCT System Francesco LaRocca; Derek Nankivil; Al-Hafeez Dhalla; Ryan P. McNabb; Cynthia A. Toth; Sina Farsiu; Joseph A. Izatt View Presentation 1489 - B0216. Handheld High Speed 500 kHz Swept Source OCT Device Using a Micro Scanning Mirror Chen D. Lu; Martin F. Kraus; Ireneusz Grulkowski; Jonathan J. Liu; Benjamin Potsaid; Vijaysekhar Jayaraman; Alex E. Cable; Joachim M. Hornegger; Jay S. Duker; James G. Fujimoto View Presentation 1490 - B0217. Application of Raman Spectroscopy to Detect Retinoblastoma Tumor Viability Olena Y. Palyvoda; John Roarty View Presentation 1491 - B0218. VCSEL Laser Technology for Ultrahigh Speed and Extended Depth Range OCT Imaging of the Retina and Anterior Eye Benjamin Potsaid; Jonathan J. Liu; WooJhon Choi; Ireneusz Grulkowski; Vijaysekhar Jayaraman; James Y. Jiang; Peter J. Heim; Jay S. Duker; Alex E. Cable; James G. Fujimoto View Presentation 1492 - B0219. Ultrahigh speed polarization sensitive OCT of the anterior and posterior eye using a 1050 nm VCSEL light source Al-Hafeez Dhalla; Jonathan J. Liu; Kathrin J. Mohler; Benjamin Potsaid; Chen D. Lu; Vijaysekhar Jayaraman; Alex E. Cable; David Huang; James G. Fujimoto View Presentation 1493 - B0220. Photoacoustic ophthalmoscopy guided by real-time fundus camera Hao F. Zhang; Shuliang Jiao; Tan Liu; Wei Song View Presentation 1494 - B0221. Pump-Probe Laser Imaging of Pigment in Conjunctival Melanocytic Lesions Prithvi Mruthyunjaya; Lejla Vajzovic; Jesse W. Wilson; Francisco E. Robles; Thomas J. Cummings; Warren S. Warren View Presentation 1495 - B0222. A Novel Technique for Combined Retinal and Choroidal Imaging Using Optical Coherence Tomography Matthew Richardson; Raeba Mathew; Sobha Sivaprasad View Presentation 1496 - B0223. Modification of Spectralis HRA + OCT for intraoperative multi-modality imaging in pediatric retinal diseases Timothy Fung; Mahiul M. Muqit; David Mordant; Lewis Smith; Chetan K. Patel View Presentation 1497 - B0224. Scale- and rotation-invariant fundus tracking system for noninvasive OCT retinal micro-capillary network visualization and retinal disease progression OCT measurements Dawid Borycki; Maciej Szkulmowski; Daniel Ruminski; Danuta Bukowska; Bartosz L. Sikorski; Iwona Gorczynska; Andrzej Kowalczyk; Maciej Wojtkowski View Presentation 1498 - B0225. Automatic axial biometry of the whole eye using ultra-long scan depth optical coherence tomography Jianguang Zhong; Yilei Shao; Aizhu Tao; Hong Jiang; Che Liu; Jianhua Wang View Presentation 1499 - B0226. Cost-Effective Active Retinal Tracker to Stabilize Eye Motions in Optical Coherence Tomography Yiheng Lim; Roy de Kinkelder; Barry Cense View Presentation 1500 - B0227. Quantification of local hemoglobin oxygen saturation by 800 nm DualWindow Spectroscopic OCT Roman V. Kuranov; Chad Oian; Gary Noojin; Kurt Schuster; Aurora D. Shingledecker; David J. Stolarski; Jeff Oliver View Presentation 1501 - B0228. High Three-Dimensional Resolution and Long Imaging Range Retinal Optical Frequency Domain Imaging using Dual-Axicon Lens Illumination Jongshin Kim; Yongjoo Kim; Jeeyun Ahn; Se Joon Woo; Kyu Hyung Park; Wang-Yuhl Oh View Presentation 1502 - B0229. A Robotic-controlled Intraocular OCT Probe Jin H. Shen; Haoran Yu; Nabil Simaan; Karen M. Joos View Presentation 1503 - B0230. Retinal Imaging Using a 25-gauge OCT Endoprobe through Vitreous and Vitreous Substitutes Anita Agarwal; Jin H. Shen; Karen M. Joos View Presentation 1504 - B0231. Slit-Lamp Adapted Ultra-High Resolution OCT for Imaging of the Retinal Neural Tissue Structure and Vascular Morphology Delia DeBuc; Omaima M. Nomir; Hong Jiang; Jianhua Wang View Presentation 1505 - B0232. Features of Cone Photoreceptors on Adaptive Optics Retinal Imaging Manickam N. Muthiah; Carlos Gias; Joe Zhong; Zoe McClelland; Peter J. Coffey; Lyndon daCruz View Presentation 1506 - B0233. Comparison of the multifocal electroretinogram (mfERG) a-wave amplitude and cone density Michael Klein; Suresh Viswanathan; Stephen A. Burns; Gang Huang View Presentation 1507 - B0234. A New Retinal Lesion:Characterization of the Gliotic Lesion, or Gli, by Review of AOSLO and SDOCT Images from 851 Subjects Thomas Gast; Toco Y. Chui; William H. Swanson; Ann E. Elsner; Joel A. Papay; Stephen A. Burns View Presentation 1508 - B0235. Adaptive optics enhanced SLO/OCT imaging of human photoreceptors with axial eye tracking Michael Pircher; Franz Felberer; Julia S. Kroisamer; Bernhard Baumann; Stefan Zotter; Ursula Schmidt-Erfurth; Christoph K. Hitzenberger View Presentation 1509 - B0236. Characterizing foveal specialization in albinism using AOSLO and SDOCT Melissa A. Wilk; John T. McAllister; Teresa Patitucci; Adam M. Dubis; Kimberly E. Stepien; William Wirostko; Deborah M. Costakos; C G. Summers; Murray Brilliant; Joseph Carroll View Presentation 1510 - B0237. Adaptive optics and 'en face' OCT imaging of the outer retina in Type 2 Macular Telangiectasia Ferenc B. Sallo; Valerie Krivosic; Kiyoko Gocho; Michel Paques; Tunde Peto; Alan C. Bird; Alain Gaudric View Presentation 1511 - B0238. Improved cellular resolution retinal imaging with aberration free and pupil wander free reflective Adaptive Optics – Optical Coherence Tomography Imaging System Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 69 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Sang Hyuck Lee; Yifan Jian; Robert J. Zawadzki; John S. Werner View Presentation 1512 - B0239. Adaptive optics imaging of eyes with epiretinal membrane before and after surgery Fabio Scarinci; Guido . Ripandelli ; Gaetano Cupo; Marco Andrea Pileri; Sebastiano Serrao; Marco Lombardo View Presentation 1513 - B0240. Adaptive optics and psychophysical measures for anatomical and functional cone patterns association in normal subjects Ieva Sliesoraityte; Saddek Mohand-Said; Victoria Ganem; Jose A. Sahel View Presentation 1514 - B0241. Photoreceptor deflection around subretinal drusenoid deposits (SDD) revealed by adaptive optics scanning laser ophthalmoscopy (AOSLO) Yuhua Zhang; Xiaolin Wang; Ernesto Blanco; Mark Clark; Clark D. Witherspoon; Christopher A. Girkin; Cynthia Owsley; Christine A. Curcio View Presentation 1515 - B0242. Improved visualization of optical coherence tomography (OCT) image using line-divided pattern matching technique Naoki Kobayashi; Toshiaki Nakagawa; Takayoshi Suzuki; Shinji Toyoda View Presentation 1516 - B0243. A fast auto-focus for digital slit lamp imaging Tobias Rudolph; Stephan Wyder; Sandro I. De Zanet; Sebastian Wolf; Jens H. Kowal View Presentation 233. Binocular Vision and Age Effects on Vision Moderator(s): Allen Cheong (Hong Kong Polytechnic University) 8:30 AM - 10:15 AM; Exhibit / Poster Hall View Session Details 8:30 AM - 10:15 AM 1517 - B0303. Oblique effects in V2 neurons of infant macaque monkeys Xiaofeng Tao; Bin Zhang; Guofu Shen; Earl L. Smith; Yuzo M. Chino View Presentation 8:30 AM - 10:15 AM 1518 - B0304. Interocular acuity differences alter the spatial frequency tuning of stereopsis Ashley Craven; Truyet Tran; Kevin Gustafson; Thomas H. Wu; Kayee So; Dennis M. Levi; Roger W. Li View Presentation 8:30 AM - 10:15 AM 1519 - B0305. Enhancing stereoacuity through perceptual learning in normal vision: Specificity for spatial frequency and orientation Truyet Tran; Kayee So; Calvin Nguyen; Tszwing Leung; Sandy Chat; Dennis M. Levi; Roger W. Li View Presentation 1520 - B0306. Factors influencing stereoacuity levels after surgery to correct unilateral 8:30 AM - 10:15 AM developmental cataracts in children Soo Jung Lee; Nam Eok Kim; Jung Min Park View Presentation 8:30 AM - 10:15 AM 1521 - B0307. Do Bangerter filters promote binocular function in amblyopes? Daming Deng; Jinrong LI; Benjamin Thompson; Minbin Yu; Robert F. Hess View Presentation 8:30 AM - 10:15 AM 1522 - B0308. Optimizing binocular vision of pseudophakes with uncorrected astigmatism Veerendranath Pesala; Prashant Garg; Shrikant R. Bharadwaj View Presentation 8:30 AM - 10:15 AM 1523 - B0309. Effects of refractive blur and clothing on night-time pedestrian visibility Joanne M. Wood; Ralph Marszalek; Trent Carberry; Philippe Lacherez; Sumanth Virupaksha; Michael J. Collins View Presentation 8:30 AM - 10:15 AM 1524 - B0310. Pupil Changes under Scotopic and Photopic illumination Li Chen; Dimitri Chernyak View Presentation 8:30 AM - 10:15 AM 1525 - B0311. The Correlation between Visual Acuity, Refraction and Cognitive Function in the Elderly Oriel Spierer; Naomi Fischer; Adiel Barak; Michael Belkin View Presentation 8:30 AM - 10:15 AM 1526 - B0312. Relationship between dynamic vision and balance in older adults Allen M. Cheong; Kar Ho Siong; William Tsang; Ho Lung Henry Chan View Presentation 8:30 AM - 10:15 AM 1527 - B0313. Effect of Visual Function on Giving and Receiving Help in an Older Adult Population Monique J. Leys; Priyanka Jain; Merideth Smith; G. Jamie Miller; Kenneth B. Mitchell; J V. Odom View Presentation 1528 - B0314. Online Assessment of Contrast Sensitivity and Hallucinations in 8:30 AM - 10:15 AM Parkinson’s Disease Mary Lou Jackson; Jennifer Wallis; Paul Wicks; Peter Bex View Presentation 8:30 AM - 10:15 AM 1529 - B0315. Contrast acuity in Lewy Body Disease Helene Kergoat; Guillaume Carcenac; Mireille Parent View Presentation 234. Retina and Diabetic Retinopathy Moderator(s): Oliver Comyn (Moorfields Eye Hospital) and Stela Vujosevic (Department of Ophtahlmology University of Padova) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 1530 - C0020. Retinal Microvascular Signs and Incident Cardiovascular Event in Asians Carol Y. Cheung; Wan Ting Tay; Mohammad K. Ikram; Paul Mitchell; Jie Jin Wang; Charumathi Sabanayagam; E Shyong Tai; Tien Y. Wong View Presentation 1531 - C0021. Severity And Progression Of Diabetic Retinopathy In Type 2 Macular Telangiectasia (MacTel) Simona Degli Esposti; Tunde Peto; Irene Leung; Ferenc B. Sallo; Catherine A. Egan View Presentation 1532 - C0022. Association between Presence and Severity of Diabetic Retinopathy and Coronary Artery Disease Adam J. Plant; Thomas H. Hong; Annette Kifley; Aravinda Thiagalingam; Paul Mitchell View Presentation 1533 - C0023. Novel and Traditional Biomarkers of Diabetic Retinopathy Severity: Multicategory Classifications Modeling Wan Ling Wong; Jialiang Li; Xiang LI; Ecosse L. Lamoureux; Carol Y. Cheung; Tien Y. Wong View Presentation 1534 - C0024. Diabetic retinopathy mobidity among known diabetics in urban slums of Mumbai, India, are comparable to urban trends anywhere in the world Sunita Mohan; Ashwini Rogiye; Manish Sonawane; Hemangi Gawali; Radhika Srinivasan; Sundaram Natarajan; Govindasamy Kumaramanickavel; Catherine A. McCarty View Presentation 1535 - C0025. Meta-analysis examining the systemic safety profile of intravitreal ranibizumab injections in AMD, RVO and DME Robert L. Avery; Steven F. Francom; Phillip Lai; Chad Melson; Sung B. Cha; Lisa Tuomi Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 70 sur 222 View Presentation 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 1536 - C0026. Prevalence and risk factors for Diabetic Retinopathy In an Urban Chinese population: The Singapore Chinese Eye Study Gavin S. Tan; Mohammad K. Ikram; Yingfeng Zheng; Merwyn Chew; Ching-Yu Cheng; Ecosse L. Lamoureux; Paul Mitchell; Jie Wang; E Shyong Tai; Tien Y. Wong View Presentation 1537 - C0027. Major Risk Factors of Diabetic Retinopathy and their Relative Importance: a Meta-analysis Pooling Data from Individual Subjects in 13 Studies Jing Xie; Barbara E. Klein; Jonathan Shaw; Miho Yasuda; Jacqueline M. Dekker; Tarun Sharma; Korapat Mayurasakorn; Viswanathan Mohan; Ecosse L. Lamoureux; Tien Y. Wong View Presentation 1538 - C0028. Chronic Kidney Disease and Diabetic Retinopathy in an Asian population Charumathi Sabanayagam; Mohammad K. Ikram; Huang Huiqi; Paul Mitchell; Jie Wang; Su Chi Lim; Ecosse L. Lamoureux; E Shyong Tai; Tien Y. Wong View Presentation 1539 - C0029. Impact of Sociodemographic Factors and Glycosylated Hemoglobin on the Incidence of Diabetic Macular Edema in a Large Nationwide Sample Mehnaz Khan; Nidhi Talwar; Joshua D. Stein View Presentation 1540 - C0030. Risk Factors Associated with Diabetic Macular Edema: A Longitudinal Analysis of 447,407 Persons with Diabetes in a U.S. Managed Care Network Nidhi Talwar; Mehnaz Khan; Thomas W. Gardner; Joshua D. Stein View Presentation 1541 - C0031. Twenty Years On. More or Less Diabetic Retinopathy at Diagnosis of Type 2 Diabetes? Ahmed Sallam; Irene M. Stratton; Steve Aldington; Mark G. Histed; Peter H. Scanlon View Presentation 1542 - C0032. Prevalence and Progression of Diabetic Retinopathy in Rural China: The Handan Eye Study Wang Fenghua; Yuanbo Liang; Jie Jin Wang; Tien Y. Wong; Ningli Wang View Presentation 1543 - C0033. Cost of a Community-Based Diabetic Retinopathy Screening Program Margaret Byrne; Byron L. Lam; Dorothy F. Parker; Manuel Ocasio; Jenelle Lin; David J. Lee View Presentation 1544 - C0034. Factors that contribute to vision-related quality of life scores in patients with diabetic retinopathy Roxanne Crosby-Nwaobi; Angus Forbes; Sobha Sivaprasad View Presentation 1545 - C0035. Epidemiological study of diabetic retinopathy in community diabetic care program in Beijing urban area Yanhong Zou; Qian Li; Ning Zhang; Wei Jia; Xipu Liu View Presentation 1546 - C0036. Cost-utility analysis of screening program for diabetic retinopathy in Japan: a probabilistic Markov modeling study Ryo Kawasaki; Yoko Akune; Yoshimune Hiratsuka; Masakazu Yamada View Presentation 1547 - C0037. A Multi-Center Study of Diabetes Eye Screening in Community Settings in the United States Cynthia Owsley; David S. Friedman; Julia A. Haller; David J. Lee; Jinan Saaddine View Presentation 1548 - C0038. Effectiveness of Telemedicine Strategies for Diabetic Retinopathy Screening: A Systematic Review Andrea C. Coronado; Hargurinder Singh; John Costella; Monali Malvankar; Bin Xie; William G. Hodge View Presentation 1549 - C0039. Long-term comparative effectiveness of telemedicine to detect diabetic retinopathy Steven L. Mansberger; Stuart K. Gardiner; Shaban Demirel; Thomas Becker View Presentation 1550 - C0040. Teleretinal Screening in Mexico: a Pilot Project as part of a Comprehensive Diabetes Care Clinic in Monterrey, México Gilberto Zamora; Javier A. Lozano; Richard VanNess; Sheila C. Nemeth; Omar Meza; Eduardo Martiñón; Elizabeth McGrew; Peter Soliz View Presentation 1551 - C0041. Developing Best Practices for Analyzing Real-World Data in Vision Care: Comparison of Approaches for Imputing Ethnicity from a High Volume Urban Vision Clinic Julia A. Haller; Yang Dai; Philip P. Storey; Lisa A. Hark; Laura Pizzi; Benjamin Leiby; Ann P. Murchison View Presentation 1552 - C0042. Non-mydriatic fundus camera screening for diabetic retinopathy in a Northern California safety-net setting Brian Toy; Shelley Day View Presentation 1553 - C0043. Ocular Conditions of Diabetics and Non-Diabetics in a Primary Care Setting Richard VanNess; Gilberto Zamora; Sheila C. Nemeth; Elizabeth McGrew; Wendall C. Bauman; Son Nguyen; Peter Soliz View Presentation 1554 - C0044. A Ten-Year Retrospective Epidemiological Study of Retinal Vein Occlusions in a Large Urban Public Hospital Brendan Butler; Lisa Park; Shantan Reddy View Presentation 1555 - C0045. The Angle as a Measure of the Vein Narrowing at Retinal Arteriovenous Crossings Huiyuan Liang; Qingyuan Liang View Presentation 1556 - C0046. Venous Collateral Circulation between Superior and Inferior Halves of the Retina May Be Normal Cross-raphe Drainage Qingyuan Liang; Huiyuan Liang; David T. Wong View Presentation 1557 - C0047. Observational and Surgical Course of Vitreomacular Traction Syndrome Adam Carver; Robert Leonard View Presentation 1558 - C0048. The Relationship of Retinopathy Signs and Chronic Kidney Disease in Persons without Diabetes: the Singapore Epidemiology of Eye Disease (SEED) Study Merwyn Chew; Charumathi Sabanayagam; Wan Ting Tay; Su Chi Lim; E Shyong Tai; Tien Yin Wong View Presentation 1559 - C0049. German Health Services Research Study: Estimated Prevalence and Incidence of Pathologic Myopia and Lack of Classification of different Stages of Pathologic Myopia Marc Schargus; Daniel Pauleikhoff; Gisela Haeusser-Fruh; Mathias M. Maier View Presentation 1560 - C0050. Negative Electroretinograms in the Military Personnel Complaining Night Blindness in the Military Mustafa Eren; Gungor Sobaci; Yusuf Uysal; Uzeyir Erdem View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 71 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 1561 - C0051. Gestational Diabetes Mellitus (GDM) and Changes in Retinal Microvasculature 6 months after Delivery Lingjun Li; Carol Y. Cheung; Mohammad K. Ikram; Seang-Mei Saw; Tien Y. Wong View Presentation 1562 - C0052. Ethnic disparity in prevalence of retinal vein occlusions amongst older Australians - the Melbourne Collaborative Cohort Study Khin Zaw Aung; Galina A. Makeyeva; Madeleine K. Adams; Elaine W. Chong ; Paul N. Baird; Robyn H. Guymer; Liubov D. Robman View Presentation 1563 - C0053. Subretinal neovascularisation in Macular Telangiectasia type 2: Baseline characteristics and progression over two years Konstantinos Balaskas; Ferenc B. Sallo; Irene Leung; Daniela Florea; Alan C. Bird; Tunde Peto View Presentation 1564 - C0054. Diagnostic disparities in testing for hydroxychloroquine (HCQ)-related ocular toxicity Victor A. Chen; Maria Carolina Ortube; Steven Nusinowitz; Michael B. Gorin View Presentation 1565 - C0055. Prevalence and risk factors of retinal vein occlusion in Asian Indians comparative study between Singapore and India Mayuri Bhargava; Victor Koh; Carol Y. Cheung; Wan Ling Wong; Jie Wang; Paul Mitchell; Tin Aung; Tien Y. Wong View Presentation 1566 - C0056. Longitudinal Changes in Blood Pressure and Retinal Vasculature: The Singapore Malay Eye Study Michelle Lim; Carol Y. Cheung; Lingjun Li; Jie Wang; Mohammad K. Ikram; Ecosse L. Lamoureux; Ching-Yu Cheng; Tien Y. Wong View Presentation 1567 - C0057. Genotype-phenotype analysis of male subjects affected by choroideremia Paul Freund; Mira Furgoch; Ian M. MacDonald View Presentation 1568 - C0058. The Prevalence of Retinal Cysts in an Aging Population: the Beaver Dam Eye Study Stacy M. Meuer; Chelsea E. Myers; Ronald Klein; Barbara E. Klein View Presentation 1569 - C0059. Determinants of Macular Thickness using Spectral Domain Optical Coherence Tomography in Healthy Eyes: the Singapore Chinese Eye Study PREETI GUPTA; Elizabeth Sidhartha; Yih Chung Tham; Jiemin Liao; Ching-Yu Cheng; Tien Y. Wong; Tin Aung; Carol Y. Cheung View Presentation 1570 - C0060. Risk of Central Serous Chorioretinopathy in Adults Prescribed Oral Corticosteroids Der-Chong Tsai; Shih Jen Chen; Pesus Chou; Hsin-Bang Leu View Presentation 1571 - C0061. Ocular Findings In Aplastic Anemia: Multicenter Study and Literature review Ramzi Alameddine; Ahmad M. Mansour; Jong Wook Lee; Seung Ah Yahng; Kyu Seop Kim; Maha Shahin; Nelson Hamerschlak; Rubens Belfort Neto; Shree K. Kurup View Presentation 1572 - C0062. Frequency and risk factors of retinal hemorrhages in adult Chinese in rural and urban China Liang Xu; Ya Xing Wang; Jin Qiong Zhou; Jost B. Jonas View Presentation 1573 - C0063. Retinal Microvascular Caliber and Coronary Artery Stenoses Bamini Gopinath; Adam J. Plant; Aravinda Thiagalingam; George Burlutsky; Tien Y. Wong; Paul Mitchell View Presentation 235. Ocular Disease Expression, Proteomics, Biomarkers, and Polymorphisms Moderator(s): Roger Beuerman (Singapore Eye Research Inst) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 1574 - D0001. New Potential Biomarker of Neurofibromatosis Type I, discovered with Multi-Spectral Imaging (MSI) of the Retinal Pigment Epithelium (RPE) and Choroid Dorothy Hitchmoth; Jerome Sherman View Presentation 1575 - D0002. Quantitative Proteomic Analysis of TIMP3 Dysfunction Geeng-Fu Jang; Alecia Cutler; Lei Zhang; John S. Crabb; Heidi Stoehr; John W. Crabb; Bela Anand-Apte View Presentation 1576 - D0003. Association of the polymorphism of the 5' UTR region of the HBD1 gene in patients with infectious blepharitis Hector J. Perez-Cano; Ingrid V. Gonzalez Leon; Oscar Fernandez-Vizcaya; Justine Nolasco-Lopez; Jean R. Clemenceau; Atzin Robles-Contreras View Presentation 1577 - D0004. Comparative Analysis of Donor Medical History and Disease Attributes Kieron Torres; Verity F. Oliver; Raymond Enke; Jin Song; Shannath L. Merbs View Presentation 1578 - D0005. Treatment of Usher syndrome with antisense oligonucleotides Jennifer J. Lentz; Mette Flaat; Francine M. Jodelka; Anthony Hinrich; Yongdong Zhou; Kate McCaffery; Dominik M. Duelli; Nicolas G. Bazan; Frank Rigo; Michelle L. Hastings View Presentation 1579 - D0006. Genetic Heterogeneity Among Patients with Pericentral Retinitis Pigmentosa Jason Comander; Aliete Langsdorf; Shyana Harper; Carol Weigel-DiFranco; Mark B. Consugar; Michael Sandberg; Xiaowu Gai; Joseph A. White; Eliot L. Berson; Eric A. Pierce View Presentation 1580 - D0007. Distinct molecular mechanisms responsible for different retinopathies caused by CRX mutations DNH and LFH Alan Zhang; Nicholas M. Tran; Xiaodong Zhang; Shiming Chen View Presentation 1581 - D0008. Comprehensive genetic analysis of an Usher I patient cohort Kinga M. Bujakowska; Emily Place; Mark B. Consugar; Daniel G. Taub; Aliete Langsdorf; Carol Weigel-DiFranco; Shyana Harper; Xiaowu Gai; Eliot L. Berson; Eric A. Pierce View Presentation 1582 - D0009. Epigenetic factors in the pathogenesis of corneal dystrophy Xiaohua Li; Xiaohua Li; Min Yuan; Ruijie Yin View Presentation 1583 - D0010. Biomarkers for Neuronal Injury following Blast Trauma to the Eye Steven G. Hart; XiangDi Wang; Tonia S. Rex; Eldon E. Geisert View Presentation 1584 - D0011. Colorimetric Image Analysis in Detection of Leukocoria from Retinoblastoma in Snapshots Taken by Standard Digital Photography Katherine E. Talcott; Elizabeth Shaw; Rebecca Holden; Brandon W. Taylor; Erich J. Baker; Greg Hamerly; Alex Kentsis; Shizuo Mukai; Carlos Rodriguez-Galindo; Bryan F. Shaw View Presentation 1585 - D0012. Initial proteomic analysis of structural changes in the aging human vitreous Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 72 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Qianru Zhang; Ying-Bo Shui; Anne Kettler; James P. Malone; Robert R. Townsend; David C. Beebe View Presentation 1586 - D0013. Manipulation of the MicroRNA Content of Endothelial Progenitor Cellderived Extracellular Vesicles David A. Simpson; Eoin Brown; Christina L. O'Neill; Reinhold J. Medina; Jasenka Guduric-Fuchs View Presentation 1587 - D0014. P2X7 Expression in Vitrectomy Samples Cheryl Chi; Deeba Husain; Celeste B. Rich; Nicole H. Siegel; Vickery E. TrinkausRandall View Presentation 1588 - D0015. Pro-inflammatory cytokines induce apoptosis of human retinal endothelial cells by downregulating Hsp27 Ram H. Nagaraj; Allison Palmer; Rooban B. Nahomi View Presentation 1589 - D0016. Probing the sensitivity of rhodopsin expression to chromophore levels in the retina Lauren L. Daniele; Edward N. Pugh View Presentation 1590 - D0017. Vitreoretinal interface abnormalities and viscoelastic behavior of the vitreous Sanket U. Shah; David C. Reed; Sam Abbassi; Ryan Freeman; Pooria Sharif-Kashani; Pirouz Kavehpour; Jean-Pierre Hubschman View Presentation 1591 - D0018. Gene expression profiling of the human macula Kristis Vevis; Michael B. Powner; Jenny Mckenzie; Meidong Zhu; Mark C. Gillies; Marcus Fruttiger View Presentation 1592 - D0019. Identification of piRNAs in the Retina Yingfeng Zheng; Qilin Wang; Xinyang Lin; Mingguang He View Presentation 1593 - D0020. Unpredictable Consequences of Systemic Valproic Acid Treatment on the Rate of Photoreceptor Loss in Different Pde6b Rd-mutations Kenneth P. Mitton; David W. Byrd; Eduardo Guzman; Adrianne Wallace; Trung Tran; Jason Sotzen View Presentation 1594 - D0021. MicroRNA-21 (miR-21) Induces Down-regulation Of PEDF In Retinal Pigmented Epithelial Cells By Suppression Of PPAR Alpha Manuela Bartoli; Chaunte E. Stampley; Sean Shaw; Pamela M. Martin; Folami Lamoke View Presentation 1595 - D0022. Suppression of microglial inflammatory response by sigma receptor 1 ligand (+)-Pentazocine Jing Zhao; Sylvia B. Smith; Kathryn Bollinger View Presentation 236. Glaucoma Biochemistry and Mechanisms Moderator(s): John Fingert (University of Iowa) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 1596 - D0023. Association of LOXL1 Gene Polymorphisim in Turkish Population with Pseudoexfoliation Syndrome and Glaucoma Nilgun Yildirim; Yetkin Yaz; Oguz Cilingir; Fez an Sahin; Zafer Yüksel View Presentation 1597 - D0024. Elevated TGFβ1 concentration in the plasma of glaucoma patients John Kuchtey; L. Goodwin Burgess; Megan B. Parks; Jessica Kunkel; Milam A. Brantley; Rachel W. Kuchtey View Presentation 1598 - D0025. Association of the T allele of rs41435250 of LOXL1 with elevated risk of exfoliation syndrome and exfoliation glaucoma in a Mexican population Dalia C. Guadarrama; Juan C. Zenteno; Antonio Miranda; Celia Elizondo View Presentation 1599 - D0026. Regulation of rhodopsin gene expression by DNA methylation Jin Song; Tomohiro Masuda; Donald J. Zack; Shannath L. Merbs View Presentation 1600 - D0027. MicroRNA 184 regulates Ezrin expression and potentially impacts Ezrindependent functions in human Retinal Pigment Epithelium Nishantha Gunawardena; Nady Golestaneh; Maria Kokkinaki; Mia Gunawan View Presentation 1601 - D0028. The role of Rgcs1 gene Spink2 in Autophagy and ganglion cell susceptibility to optic nerve damage Margaret Maes; Joel Dietz; Cassandra Schlamp; Robert W. Nickells View Presentation 1602 - D0029. mTor is Involved in the Dexamethasone Induced Expression of β3 Integrin in Human Trabecular Meshwork Cells Jennifer A. Faralli; Debjani Gagen; Donna M. Peters View Presentation 1603 - D0030. An analysis of normal and glaucomatous human lamina cribrosa and trabecular meshwork cell behaviours as determined by the surrounding extracellular matrix Sara McNally; Deborah M. Wallace; Colm J. O'Brien View Presentation 1604 - D0031. Mitochondrial membrane potential, as a measure of mitochondrial function, in patients with normal tension glaucoma vs ocular hypertension Gerassimos Lascaratos; David Chau; Haogang Zhu; Anthony Schapira; David F. Garway-Heath View Presentation 1605 - D0032. Changes in antibodies from glaucoma patients lead to changes in apoptosis pathways of neuroretinal cells Katharina Bell; Corina Wilding; Sebastian Funke; Norbert Pfeiffer; Franz H. Grus View Presentation 1606 - D0033. HUMAN OCULAR DISTRIBUTION OF PRODUCTS OF THE POAGASSOCIATED CDKN2B-AS1 GENE CLUSTER REGION John P. Wood; Glyn Chidlow; Robert J. Casson; Shiwani Sharma; Kathryn P. Burdon; Jamie E. Craig View Presentation 1607 - D0034. Analysis of the covalent high molecular weight protein complex containing optineurin and its relationship with glaucoma Jie Gao; Masafumi Ohtsubo; Yoshihiro Hotta; Shinsei Minoshima View Presentation 1608 - D0035. Post-transcriptional regulation of γ-synuclein expression and its role in glaucomatous alterations Andrei Surguchov; Irina G. Surgucheva View Presentation 1609 - D0036. Soluble guanylate cyclase: an emerging therapeutic target in open angle glaucoma Emmanuel S. Buys; Yu-Chieh Ko; Clemens Alt; Haiyan Gong; Peter Brouckaert; Janey L. Wiggs; Meredith S. Gregory-Ksander; Louis R. Pasquale; Kenneth D. Bloch; Bruce R. Ksander View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 73 sur 222 8:30 AM - 10:15 AM 1610 - D0037. Mammalian Expression and Biophysical Examination of Human WildType Optineurin Protein Hongyu Ying; Xiang Shen; Minhua Wang; Beatrice Yue View Presentation 237. Corneal Cross-linking and Biomechanics Moderator(s): Arthur Hammer (Geneva university Hospital) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 1611 - D0246. The efficacy of corneal cross-linking shows a sudden decrease with very high intensity UV-light and short treatment time Jeremy Wernli; Silvia Schumacher; Eberhard Spoerl; Michael C. Mrochen View Presentation 1612 - D0247. Corneal Biomechanical Properties after UV Cross-linking in the Rabbit Michael D. Twa; Jiasong Li; Ravi Kiran Manapuram; Floredes M. Menodiado; Salavat Aglyamov; Stanislav Emelianov; Kirill Larin View Presentation 1613 - D0248. The Rigidity of Corneas before and after Corneal Cross-linking – as measured by Corvis® ST Sashia Bak-Nielsen; Iben Bach Pedersen; Anders Ivarsen; Jesper Hjortdal View Presentation 1614 - D0249. Association of Ambient Solar Radiation with Biomechanical Properties of the Cornea In an elderly population: The Alienor Study Cedric Schweitzer; Cecile Delcourt; Florence Malet; Melanie Le Goff; Jean-Francois Korobelnik; Marie B. Rougier; Marie-Noelle Delyfer; Jean Francois Dartigues; Pascale Barberger-gateau; Joseph Colin View Presentation 1615 - D0250. Effect of UVA-Rb cross-linking on through-thickness strains in canine corneas Joel Palko; Xueliang Pan; Jun Liu View Presentation 1616 - D0251. In Vivo Evaluation of Corneal Biomechanical Properties After Corneal Collagen Cross-linking Therapy Raksha Urs; Harriet Lloyd; Ronald H. Silverman View Presentation 1617 - D0252. Long Term Follow-Up of Corneal Topographic Indices Following Collagen Crosslinking In Eyes with Keratoconus Erick Hernández-Bogantes; Lihteh Wu; David Flikier View Presentation 1618 - D0253. Comparison of corneal changes between standard and transepithelial riboflavin-UVA crosslinking method using multiphoton microscopy and second harmonic imaging Praveena Gupta; Best Anyama; Kevin M. Wells; Massoud Motamedi; Bernard F. Godley; Gracie Vargas View Presentation 1619 - D0254. Biaxial Biomechanical Study of UVA-RF Corneal Cross-linking William A. Eddington; Marc D. Friedman; Evan A. Sherr; David Muller View Presentation 1620 - D0255. Finite Element Analysis of Treatment of Corneal Astigmatism with Collagen Crosslinking IBRAHIM SEVEN; Abhijit Sinha Roy; William J. Dupps View Presentation 1621 - D0256. Corneal geometric stress factor to evaluate response to corneal collagen cross-linking in keratoconus Riccardo Vinciguerra; Cynthia J. Roberts; Ashraf M. Mahmoud; Claudio Azzolini; Paolo Vinciguerra View Presentation 1622 - D0257. Evaluation of the riboflavin and Ultraviolet light effect on keratocytes cultivated in vitro Joyce L. Covre; Priscila C. Cristovam; Renata R. Loureiro; Rossen M. Hazarbassanov; Mauro S. Campos; Élcio H. Sato; Jose A. Gomes View Presentation 1623 - D0258. Long term evaluation of corneal permeability following cross-linking in a live animal model Jay M. Stewart; Ricardo Lamy; Elliot Chan View Presentation 1624 - D0259. Modulation of matrix stiffness throughout corneal wound healing following phototherapeutic keratectomy Sara M. Thomasy; Vijaykrishna K. Raghuanthan; Peter C. Strom; Jasmyne C. Sermeno; Paul Russell; Christopher J. Murphy View Presentation 1625 - D0260. Comparison of Biomechanical and Tomographic Data in Subclinical Keratoconus Paolo Vinciguerra; Renato Ambrosio; Mario R. Romano; Isaac C. Ramos; Claudio Azzolini; Silvia Trazza; Riccardo Vinciguerra View Presentation 1626 - D0261. Correlation of Biomechanic Parameters Measured by Corvis ST (Oculus®) and by Ocular Response Analyzer (ORA, Reichert®) Michael Haustein; Eberhard Spoerl; Lutz E. Pillunat View Presentation 1627 - D0262. The correlation between ocular response analyzer keratoconus match index and subjective topographic assessment using the Orbscan to screen for keratoconus Ryan A. Vasan; Ryan M. St Clair; Syed A. Hussnain; Ana G. Alzaga Fernandez; Christopher E. Starr View Presentation 1628 - D0263. Investigation of corneal vibration during air puff deformation using numerical approaches with clinical validation Zhaolong Han; Cynthia J. Roberts View Presentation 1629 - D0264. Modeling corneal response to an air puff using deformation data to derive Young’s modulus Kimberly M. Metzler; Cynthia J. Roberts; Steven M. Whitaker; Michael J. Lawrence; Jennifer E. Malik; Jeffrey P. Bons View Presentation 1630 - D0265. OCT-Vibrography: A Novel Non-Contact Method to Estimate Corneal Biomechanical Properties Sabine Kling; Ernest Chang; Giuliano Scarcelli; Nandor Bekesi; Seok H. Yun; Susana Marcos View Presentation 1631 - D0266. Regional Variation of Biomechanical Properties of Intact Eye Globes Ahmed Elsheikh; Charles Whitford; Akram Joda; Ahmed Abass; Fangjun Bao; Paolo Rama View Presentation 1632 - D0267. Effect of Different Hydration Media on Ex Vivo Corneal Elasticity Measurements Janice Dias; Noel M. Ziebarth View Presentation 1633 - D0268. Comparison of Biomechanical Effects of Small Incision Lenticule Extraction (SMILE) and Laser in situ Keratomileusis (LASIK): A Finite Element Analysis Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 74 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Study Abhijit Sinha Roy; William J. Dupps; Cynthia J. Roberts View Presentation 1634 - D0269. Biomechanical properties of the cornea and graft after Descemet's stripping endothelial keratoplasty Saima Qureshi; Ninita H. Brown; Naazli Shaikh View Presentation 1635 - D0270. Influence of Pregnancy on the Corneal Biomechanical Properties Roo Min Jun; Ga Eun Cho; Kyu-Ryong Choi View Presentation 1636 - D0271. Elastic modulus of keratocytes and myofibroblasts differ regardless of substratum stiffness Vijay K. Raghuanthan; Peter C. Strom; Sara M. Thomasy; Paul Russell; Christopher J. Murphy View Presentation 1637 - D0272. Corneal biomechanical properties among healthy Chinese, Indian and Caucasian: A pilot study Yin Zhi Wong; Andrew K. Lam View Presentation 1638 - D0273. Novel Corneal Biomechanical Parameters in Myopes vs Emmetropes Rachel Lee; Robert Chang; Ian Y. Wong; Jimmy S. Lai; Jacky W. Lee; Kuldev Singh View Presentation 1639 - D0274. The relationship between anterior segment biometry and corneal biomechanics in myopia Hetal Buckhurst; Bernard Gilmartin; Robert Cubbidge; Manbir Nagra; Nicola S. Logan View Presentation 1640 - D0275. Comparison of biomechanical properties of cornea in diabetic and nondiabetic primary open angle glaucoma patients Faruk Ozturk; Serkan Akkaya; Ertugrul Can View Presentation 1641 - D0276. Collagen Macrostructure and Corneal Shape: Lessons from Different Species Moritz Winkler; Yilu Xie; Tiffany Yuen; Golroxan Shoa; Robert Hueter; Kathy K. Svoboda; Christopher J. Murphy; Donald J. Brown; James V. Jester View Presentation 1642 - D0277. Inter- and Intra-Lamellar Slippage of Collagen Fibrils as a Potential Mechanism of Keratoconus Progression Michael Koster; Craig Boote; Keith M. Meek; Priscilla G. Fowler; Christopher A. Girkin; Guenther Meschke; Rafael Grytz View Presentation 1643 - D0278. Clear Corneal Incision: Sealability of the Manual Versus LensAR laser generated Full Thickness Incision E. Valas Teuma; Liz Dumanoir; Aissatou Barry; Gary Gray; G. Brock Magruder; Steve Bott View Presentation 1644 - D0279. Effect of Intraocular Pressure on Speed-of-Sound and Thickness in Ex Vivo Cornea in Intact Globes Harriet Lloyd; Mara Berganovsky; Ronald H. Silverman; Raksha Urs View Presentation 1645 - D0280. Change of corneal curvature under the open eye condition and the slightly closed eye condition Yuko Shibata; Hiroshi Uozato; Masakazu Hirota; Takushi Kawamorita View Presentation 238. Corneal Endothelium Moderator(s): Francois Majo (Jules Gonin Eye-Hospital) and Sanjay Patel (Mayo Clinic) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Withdrawn 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 1646 - D0281. Cyclosporin A inhibits cell death of Corneal Endothelial Cells by protecting michondrial membrane potential Toshinari Funaki; Kaori Ohtomo; Masahiro Yamaguchi; Akira Matsuda; Akira Murakami View Presentation 1647 - D0282. Success Isolation of Human Corneal Endothelial Cells for Clinical Use Jin San Choi; Matthew Giegengack; Eun Young Kim; Min Jeong Kim; Ralph D'Agostino ; Gilson Khang; Shay Soker View Presentation 1648 - D0283. A cell therapy approach to address corneal endothelial dysfunction Karen Alvarez-Delfin; Noelia J. Kunzevitzky; Alejandra D. Weisman; Richard M. Merkhofer; Jeffrey L. Goldberg View Presentation 1649 - D0284. Comparison of early corneal peripherial endothelial cell loss following femtosecond laser – assisted cataract surgery and conventional phacoemulsification Gábor L. Sándor; Ágnes I. Takács; Kinga Kranitz; Eva Juhasz; Illes Kovacs; Zoltan Z. Nagy View Presentation 1650 - D0285. Effect of glaucoma tube-shunt position on corneal thickness and endothelial cell density Euna Koo; Jing Hou; Ying Han; Jeremy D. Keenan; Robert L. Stamper; Bennie H. Jeng View Presentation 1651 - D0286. Human Cytomegalovirus-mediated inflammatory responses of corneal endothelial cells Michiko Kandori; Dai Miyazaki; Keiko Yakura; Yumiko Noguchi; Yukimi Yamamoto; Yoshitsugu Inoue; Tatsuo Suzutani View Presentation 1652 - D0287. Engineering of Human Corneal Endothelial Grafts Yingting Zhu; Bo Han; Szu-Yu Chen; Scheffer C. Tseng View Presentation 1653 - D0288. Human Corneal Endothelial Cells Cytotoxicity Study Using a Custom Chamber which Controls Temperature and Oxygen Levels Radha Pertaub; Marc D. Friedman; David Muller View Presentation 1654 - D0289. A Nonsynthetic, Biological Carrier for Cultivated Human Corneal Endothelial Cells (HCECs) for potential therapeutic purposes Jesintha Navaratnam; Eli Gulliksen; Kristine Ustgaard-Andersen; Jon K. Slettedal; Liv Drolsum; Bjorn Nicolaissen; Aboulghassem Shahdadfar View Presentation 1655 - D0290. Differences in corneal endothelial abnormalities in the central and intermediate zones in Fuchs’ corneal dystrophy Hisataka Fujimoto; Takeshi Soma; Yoshinori Oie; Shizuka Koh; Motokazu Tsujikawa; Naoyuki Maeda; Kohji Nishida View Presentation 1656 - D0291. Development and Characterization of Decellularized Human Corneal Stroma as a Scaffold for Tissue Engineering Radhika Tandon; Sujata Mohanty; Himi Singh; Deepika Gupta; Seema Sen; Seema Kashyap; Amit K. Dinda; Manjeet Jassal; Ashwini K. Agrawal View Presentation 1657 - D0292. Stemness Characteristics of Cultured Human Corneal Endothelial Cells in Various Media Young Joo Shin; Eui Sang Chung; Tae-Young Chung; Joon-Young Hyon; Won Ryang Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 75 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Wee View Presentation 1658 - D0293. CD147 Knockdown Decreases Corneal Lactate Transport and Endothelial Cell Viability Shimin Li; Tracy T. Nguyen; Joseph A. Bonanno View Presentation 1659 - D0294. Disappearance and reappearance of cilia of corneal endothelium preserved in corneal preservation media Hidetoshi Tanioka; Katsuhiko Shinomiya; Satoshi Kawasaki; Shigeru Kinoshita View Presentation 1660 - D0295. Endothelial loss and pachymetric change in patients undergoing penetrating keratoplasty with 3 years of follow Elisa D. Alegria; Regina Velasco; Oscar Baca; Alejandro Babayan View Presentation 1661 - D0296. The Resting Potential of Rat`s Corneal Endothelial Cells Nassim S. Calixto; Vinicius V. Oliveira; Renata Fleming; Sebastiao Cronemberger; Adalmir Dantas View Presentation 1662 - D0297. Wnt5a enhances cell migration through regulation of Cdc42 and RhoA pathway in human corneal endothelial cells JeongGoo Lee; Daniel Sand; J M. Heur View Presentation 1663 - D0298. Influence Of Hydrodynamic Culture Conditions On The Expression Of Cell Junctions Of Tissue-Engineered Human Corneal Endothelium Olivier Roy; Isabelle Brunette; Stephanie Proulx View Presentation 1664 - D0299. The Quebec Corneal Cell Bank: Update on Culture Success of Pathologic Human Corneal Endothelial Cells (2009-2012) Mathieu Theriault; Olivier Roy; Olivier Rochette-Drouin; Marie-Claude Perron; Isabelle Brunette; Stephanie Proulx View Presentation 1665 - D0300. Perception of Cornea and Glaucoma Subspecialists Regarding Prevalence of Corneal Decompensation with Ex-Press Shunt Placement Shalin Shah; Ngo Yen; Thompson W. Hilary; Jayne S. Weiss View Presentation 1666 - D0301. Biosafety of chitosan and collagen vitrigel membranes in the corneal endothelium of young New Zealand Rabbits Guillermo Mendoza; Judith Zavala; Marcos Garza-Madrid; Alejandro Tamez; Angel Zavala-Pompa; Gabriela Brito; Jorge A. Cortés_Ramirez; Jorge E. Valdez; Jennifer Elisseeff View Presentation 1667 - D0302. Examination of Endothelial Cell Count in HIV-Negative and Positive Donors John A. Gonzales; David C. Gritz; Patrick Gore; Roy S. Chuck View Presentation 1668 - D0303. Morphological Complexity of Mouse Corneal Endothelial Cells Revealed by Mosaic Analysis Dennis M. Defoe; Whitney J. Rich; Theresa A. Harrison View Presentation 1669 - D0304. Systematic and individual differences in donor cornea Endothelial Cell Density (ECD) measurements with specular microscopy vs. sucrose light microscopy Bart T. Van Dooren; Ilse J. Claerhout; Paul G. Mulder; Elisabeth Pels View Presentation 1670 - D0305. Oxidative Stress Causes Mitochondrial Dysfunction in Human Corneal Endothelial Cells Thore Schmedt; Cecily E. Hamill; Yuming Chen; Ula V. Jurkunas View Presentation 1671 - D0306. Theoretical and Clinical Method to quantify the Corneal Suction Pressure from normal corneas during the lifetime Andre Heck; Fernando C. Abib View Presentation 1672 - D0307. Descemet Membrane Endothelial Keratoplasty (DMEK): Large Descemetorhexis To Reduce Rebubbling Does Not Cause Postoperative Peripheral Corneal Edema Theofilos Tourtas; Julia M. Wessel; Bjoern O. Bachmann; Ursula Schlotzer-Schrehardt; Friedrich E. Kruse View Presentation 1673 - D0308. Objective Assessment of the Corneal Endothelium in Fuchs Endothelial Dystrophy Jay W. McLaren; Lori A. Bachman; Sanjay V. Patel View Presentation 1674 - D0309. Density dependency of successful in vitro cultures of human corneal endothelial cells using a dual media approach Gary S. Peh; Heng-Pei Ang; Khadijah Adnan; Xin-Yi Seah; Benjamin L. George; Jodhbir S. Mehta View Presentation 1675 - D0310. SLC4A11 is an EIPA-sensitive Na+-Dependent pHi Regulator Diego G. Ogando; Supriya S. Jalimarada; Eranga N. Vithana; Joseph A. Bonanno View Presentation 1676 - D0311. Effects of the Reliability Index called Sample Error of the corneal specular microscopy on the repeatability of the results of the examinations Fernando C. Abib; Richard Y. Hida; Ricadro Holzchuh View Presentation 1677 - D0312. Comparing Quantitative and Qualitative Indices of the Donated Corneas Maintained in Optisol GS with Those Kept in Eusol C Mozhgan Rezaei Kanavi; Mohammad Ali Javadi; Tahereh Chamani; Pejman Fahim View Presentation 1678 - D0313. Clinical Evaluation of a Novel Method to Generate Precut Tissue for Descemet Membrane Endothelial Keratoplasty (DMEK) Bjoern O. Bachmann; Ursula Schlotzer-Schrehardt; Martin Boergel; Friedrich E. Kruse View Presentation 1679 - D0314. Changes in Anterior Corneal Haze with Severity of Fuchs Endothelial Dystrophy Sejal Amin; Jay W. McLaren; Keith H. Baratz; Sanjay V. Patel View Presentation 1680 - D0315. Cell Line of Fuchs' Corneal Dystrophy Produces an Abnormal Extracellular Matrix Leona Ho; Naoki Okumura; EunDuck P. Kay; Kenta Yamasaki; Satoshi Kawasaki; Theofilos Tourtas; Ursula Schlotzer-Schrehardt; Friedrich E. Kruse; Shigeru Kinoshita; Noriko Koizumi View Presentation 1681 - D0316. Evaluation of Novel Porcine Atelocollagen Vitrigel Membrane with Curvature as Corneal Endothelial Cell Carrier Junko Yoshida; Seiichi Yokoo; Satoru Yamagami; Shiro Amano; Ayumi Oshikata; Chika Okamoto; Toshiaki Takezawa View Presentation 1682 - D0317. Prosthetic Replacement of Ocular Surface Ecosystem (PROSE) Device Wear Results in Decreased Endothelial Cell Density and Decreased Endothelial Pleomorphism Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 76 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Ryan M. St Clair; Yvonne Wang; Christopher E. Starr; Michelle N. Lee; Ana G. Alzaga Fernandez; Kimberly C. Sippel; Jessica Ciralsky; Mark Rosenblatt; Priyanka Sood View Presentation 1683 - D0318. Clinical Manifestation and Effect of Ganciclovir Therapy for Cytomegalovirus Corneal Endotheliitis Tsutomu Inatomi; Noriko Koizumi; Yuichi Ohashi; Yoshitsugu Inoue; Manabu Mochizuki; Kohji Nishida View Presentation 1684 - D0319. Expansion of corneal endothelial cells using biomimetic engineered substrates Rachelle Palchesko; James L. Funderburgh; Adam W. Feinberg View Presentation 1685 - D0320. Meganuclease Targeting HSV-1 Protects Against Corneal Endothelitis exvivo and in-vivo Eric E. Gabison; Marc Labetoulle; Marine Gailledrat; Jose A. Sahel; Benoit Chapelier View Presentation 1686 - D0321. Comparison of Endothelial Cell Density at the Central and Peripheral Regions in a DSAEK Graft Hiroko Nakagawa; Tsutomu Inatomi; Shigeru Kinoshita View Presentation 1687 - D0322. Age-Dependent Differential Gene Expression in Human Corneal Endothelium Cynthia Wang; Ricardo F. Frausto; Anthony J. Aldave View Presentation 1688 - D0323. ROCK inhibitor enhances adhesion and wound healing on human corneal endothelial cells Michael J. Nicolas; Aurélien Pipparelli; Yvan Arsenijevic; Gilles Thuret; Philippe Gain; Francois Majo View Presentation 1689 - D0324. Controlled Release of a Rho Kinase (ROCK)-Selective Inhibitor with Polylactic Acid Microspheres Sho Koda; Takashi Saito; Junji Kitano; Naoki Okumura; Shigeru Kinoshita; Yasuhiko Tabata; Noriko Koizumi View Presentation 1690 - D0325. Rho-kinase inhibitor enhances corneal endothelial cell proliferation via p27 degradation Ryohei Numata; Naoki Okumura; EunDuck P. Kay; Makiko Nakahara; Shinichiro Nakano; Morio Ueno; Shigeru Kinoshita; Noriko Koizumi View Presentation 1691 - D0326. Proliferation Propensity of Cultured Human Corneal Endothelial Cells and Their Plasticity Dictated by Culture Microenvironments Munetoyo Toda; Kana Nakata; kazuko asada; Michio Hagiya; Morio Ueno; Naoki Okumura; Noriko Koizumi; Junji Hamuro; Shigeru Kinoshita View Presentation 1692 - D0327. Cell-injection Therapy Using Rho Kinase Inhibitor in a Corneal Endothelial Dysfunction Rabbit Model Junji Kitano; Naoki Okumura; EunDuck P. Kay; Morio Ueno; Junji Hamuro; Shigeru Kinoshita; Noriko Koizumi View Presentation 1693 - D0328. Effect of ROCK inhibiter on Apoptosis in Corneal Endothelial Cells Ai Odajima; Naoki Okumura; EunDuck P. Kay; Wen Chen; Morio Ueno; Shigeru Kinoshita; Noriko Koizumi View Presentation 1694 - D0329. Rho kinase inhibitor promotes cell adhesion of corneal endothelial cells through inhibiting phosphorylation of MLC Yuki Tsujimoto; Naoki Okumura; EunDuck P. Kay; Ryohei Numata; Shigeru Kinoshita; Noriko Koizumi View Presentation 1695 - D0330. Quantitative Assessment of Endothelial Cell Loss of DMEK Prepared Grafts by Eye Bank Technicians Jeffrey D. Holiman; Julia Talajic; David Davis-Boozer; Mark A. Terry View Presentation 1696 - D0331. Interleukin-1β enhances cell migration through AP-1 and NF-κB pathway dependent FGF2 expression in human corneal endothelial cells Daniel Sand; JeongGoo Lee; J M. Heur View Presentation 1697 - D0332. The roles of TWEAK in human corneal endothelial cells Masahiro Yamaguchi; Nobuyuki Ebihara; Toshinari Funaki; Akira Murakami; Satoru Yamagami View Presentation 1698 - D0333. The transparency transcriptome: gene expression profile of human corneal endothelial cells Noelia J. Kunzevitzky; Karen Alvarez-Delfin; Richard M. Merkhofer; Alejandra D. Weisman; Jeffrey L. Goldberg View Presentation 239. WEAVR Silent Auction 9:30 AM - 4:00 PM; ARVO Central, Exhibit Hall 9:30 AM - 4:00 PM WEAVR Silent Auction 240. Visual Cycle, Retinoids and Carotenoids Moderator(s): Vladimir Kefalov (Washington University School of Medicine) and Krysten Farjo (Univ of Oklahoma Hlth Sciences) 11:00 AM - 12:45 PM; 6A 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM View Session Details Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary View Session Details 1699. Mouse Cone Dark Adaptation Relies on Two Visual Cycles and Is Substantially Retarded in Mice Lacking RDH8 and ABCA4 Alexander V. Kolesnikov; Peter H. Tang; Akiko Maeda; Leah C. Byrne; John G. Flannery; Krzysztof Palczewski; Vladimir J. Kefalov View Presentation 1700. Identification and Study of Two New 11-cis-Retinyl Ester Synthases in the Retina Joanna J. Kaylor; Jacob Makshanoff; Jennifer Yong; Tran N. Nguyen; Roxana A. Radu; Gabriel H. Travis View Presentation 1701. Substrate Specificity and Localization of AL-OL Coupling Reaction in Carp Cones Satoru Kawamura; Shinya Sato; Shuji Tachibanaki; Takashi Fukagawa View Presentation 1702. Targeting the STRA6/RBP4 Binding interaction to Treat Macular Degeneration Krysten M. Farjo; Gennadiy P. Moiseyev; Jian-Xing Ma View Presentation 1703. Evaluation of different classes of RBP4 antagonists as potential treatments for AMD Nicoleta Dobri; Qiong Qin; Jian Kong; Rando Allikmets; Janet R. Sparrow; Konstantin Petrukhin View Presentation 1704. Bestrophinopathy Large Animal Model Shows Abnormal Accumulation of Lipofuscin in the Retinal Pigment Epithelium Nestor Mas Gomez; Emily V. Dutrow; Simone Iwabe; Frank P. Stefano; Kathleen Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 77 sur 222 12:30 PM - 12:45 PM Boesze-Battaglia; Gustavo D. Aguirre; Karina E. Guziewicz View Presentation 1705. Delivery of Zeaxanthin to the Mouse Retina Binxing Li; Preejith P. Vachali; Zhengqing Shen; Brian M. Besch; Paul S. Bernstein View Presentation 241. Imaging I, GL Moderator(s): Jeffrey Liebmann (NYU School of Medicine), David Garway-Heath (University College London ) and David Greenfield (Bascom Palmer Eye Institute) 11:00 AM - 12:45 PM; 6B 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM 1706. Rates of retinal nerve fiber layer thinning in glaucoma suspect eyes Atsuya Miki; Linda M. Zangwill; Sonia Jain; Feng He; Naira Khachatryan; Naama Hammel; Jeffrey M. Liebmann; Christopher A. Girkin; Felipe A. Medeiros; Robert N. Weinreb View Presentation 1707. Parapapillary Autofluorescence and its Correlation with Neurovascular Fundus Anomalies in Primary Open Angle Glaucoma Alexandre Plouznikoff; Paul Harasymowycz View Presentation 1708. 3T Magnetic Resonance Imaging of the Posterior Visual Pathway in Early and Advanced Human Primary Open Angle Glaucoma Heather R. Connor; Sarah L. Hosking; Jacques-Donald Tournier; David F. Abbott View Presentation 1709. Spectral Domain Optical Coherence Tomography (SDOCT) Optic Nerve Head (ONH) Rim Quantification in Glaucoma and Glaucoma Suspect Eyes Using Anatomic Vs Acquired Image Frame (AIF) Regionalization Lin He; Ruojin Ren; Christy A. Hardin; Hongli Yang; Stuart K. Gardiner; Brad Fortune; Shaban Demirel; Claude F. Burgoyne View Presentation 1710. Subgrouping of Angle Closure Patients based on Anterior Segment Optical Coherence Tomography Parameters Tin Aung; Tianxia Gong; Hwee Kuan Lee; Shamira Perera; Mingguang He; David S. Friedman; Monisha E. Nongpiur View Presentation 1711. In vivo changes to lamina cribrosa pore and optic nerve head geometry in nonhuman primates with early experimental glaucoma Kevin M. Ivers; Nripun Sredar; Nimesh B. Patel; Lakshmi P. Rajagopalan; Hope M. Queener; Ronald S. Harwerth; Jason Porter View Presentation 1712. Pulse-induced Optic Nerve Head Axial Movement: Characterization by Phasesensitive OCT in Humans Ruikang K. Wang; lin an; Peng Li; Murray A. Johnstone View Presentation 242. AMD: Translational Research Moderator(s): Peter Kaiser (Cole Eye Institute) and David Brown (Retina Consultants of Houston) 11:00 AM - 12:45 PM; 6C 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 11:00 AM - 11:15 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM View Session Details 1713. Interleukin-17 neutralization ameliorates retinal degeneration in Cx3cr1-/-/Ccl2-//Crb1rd8 mice Daniel Ardeljan; Yujuan Wang; De Fen Shen; Mones S. Abu-Asab; Jingsheng Tuo; Chengrong Yu; Gary White; Sam Wadsworth; Abraham Scaria; Chi-Chao Chan View Presentation 1714. Oral administration of Apolipoprotein A-I mimetic peptide D-4F reduces lipid accumulation in murine Bruch’s membrane (BrM) Martin Rudolf; Armin Mohi; Zouhair Aherrahrou; Salvatore Grisanti; Yoko Miura View Presentation 1715. Effect of Aspirin on human ARPE-19 cells and in Mouse Model of Choroidal Neovascularization Sunali Goyal; Valeriy V. Lyzogubov; Puran S. Bora; Nalini S. Bora; Sami H. Uwaydat View Presentation 1716. Eyedrop application of CLT-005, a Stat3 inhibitor, is efficacious in animal models of Wet and Dry Age-related Macular Degeneration Rafal Farjo; Didier J. Nuno; Alexander B. Quiambao; Phillip A. Vanlandingham; Fadee Mondalek; Eric Phelps; Glenn Stoller; Drew Wassel View Presentation 1717. In vivo imaging of complement activation in mouse choroidal neovascularization using a novel monocolonal antibody against the C3 activation fragment C3d Baerbel Rohrer; Alex S. Woodell; Liudmila Kulik; Beth Coughlin; Gloriane Schnabolk; Joshua M. Thurman; Michael Holers View Presentation 1718. Intraocular Delivery of Ciliary Neurotrophic Factor (CNTF) by Encapsulated Cell Technology Implants Restores Cone Function and Day Vision in Dogs with CNGB3Achromatopsia Andras M. Komaromy; Kristin L. Koehl; Christine Harman; Pam Heatherton; Konrad Kauper; Gustavo D. Aguirre; Weng Tao View Presentation 243. DR: Factors and Function Moderator(s): Jennifer Kang Mieler (Illinois Institute of Technology) and Ursula Schmidt-Erfurth (Medical University of Vienna ) 11:00 AM - 12:45 PM; 6E AM View Session Details View Session Details 1719. Patterns of Progression in Diabetic Retinopathy. Correlation between phenotypes and genotypes Sandrina Nunes; Conceicao F. Lobo; Luísa Ribeiro; Isabel Pires; Rui Bernardes; Telmo Miranda; Maria J. Simões; Carlos Faro; Jose G. Cunha-Vaz View Presentation 1720. Neuroretinal Function and Retinal Vessel Changes over One Year Are Altered by Long-Term Blood Glucose Change in Adolescent Type 1 Diabetes Marcus A. Bearse; Michal Laron; Ann Chang; Kevin Bronson-Castain; Brian E. Wolff; Glen Y. Ozawa; Shirin Barez; Marilyn E. Schneck; Anthony J. Adams View Presentation 1721. Correlation of Number of Microaneurysms with Retinal Thickness Beng Beng Ong; Jason Arora; Amy Hammond-Kenny; Jennifer Doyle; Shahrnaz Izadi; Christine A. Kiire; Victor Chong View Presentation 1722. AGE products disrupt RPE barrier function in vitro and in vivo Mohammad Dahrouj; Yueying Liu; Craig E. Crosson; Zsolt Ablonczy View Presentation 1723. Biomarkers of Retina Macroglia Activation in the Aqueous of Human Diabetics Edoardo Midena; Marianna Berton; Silvia Bini; Alessandra Micera; Graziana Esposito; Stela Vujosevic View Presentation 1724. Structural Characteristics of Microaneurysms on Adaptive Optics Scanning Laser Ophthalmoscopy (AOSLO) and Surrounding Neural Retinal Pathology in Diabetes Jennifer K. Sun; Jan Lammer; Sonja G. Prager; Michael M. Lin; Michael C. Cheney; Paolo S. Silva; Stephen A. Burns; Lloyd P. Aiello Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 78 sur 222 View Presentation 12:30 PM - 12:45 PM 1725. Peripheral Diabetic Retinal Lesions Identified on Ultrawide Field (UWF) Imaging May Predict 3-Year Diabetic Retinopathy Progression Paolo S. Silva; Jerry Cavallerano; Jennifer K. Sun; Lloyd M. Aiello; Lloyd P. Aiello View Presentation 244. Microbial Pathogenesis Moderator(s): Jennifer LaVail (University of California, San Francisco) and Homayon Ghiasi (Cedars-Sinai Medical Center) 11:00 AM - 12:45 PM; 606/607 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM 1726. Comparative Genome Sequencing to Identify Staphylococcus aureus Virulence and Antibiotic Resistance Genes causing Keratitis Irmgard Behlau; David Lazinski; Jacqueline Martin; Susan Heimer; Elizabeth M. Leonard; Andrew Wright; Michael S. Gilmore; Claes H. Dohlman; Andrew Camilli View Presentation 1727. Efficacy of an Intravitreal Levofloxacin Implant in an Animal Model of Endophthalmitis Russell Tait; Richard Prankerd; Roy Robins-browne; Penelope J. Allen; Andrew Donohue; Dong Yang; Louise Adams; Feng Wang; Asha D'Souza; Sarah Ng View Presentation 1728. Matrix Metalloproteinase 13 as a target for suppressing corneal ulceration caused by Pseudomonas aeruginosa infection Nan Gao; Fushin X. Yu View Presentation 1729. Loss of HSV-1 induced VEGF-A during acute infection impairs the lymphangiogenic response during later stages of disease Katie M. Hudson; Min Zheng; Daniel J. Carr View Presentation 1730. Delivery of Herpes Simplex Virus DNA to Retinal Ganglion Cell Axon is Dependent on Viral Protein Us9 Jennifer H. LaVail; Jolene M. Draper; Graham S. Stephenson; Guiqing Huang; Andrea S. Bertke; Daniel A. Cortez View Presentation 1731. Signal peptide peptidase (SPP) is required for HSV-1 infectivity through interaction with glycoprotein K (gK) Sariah J. Allen; Kevin R. Mott; Yoshiharu Matsuura; Kohji Moriishi; Konstantin G. Kousoulas; Homayon Ghiasi View Presentation 1732. Prevention of Cytomegalovirus-Induced Retinitis By Intravenous Administration of Virus-specific siRNA Brendan Marshall; Jason Covar; Sally S. Atherton; Ming Zhang View Presentation 245. Genetic Epidemiology: GWAS and SNPs Around the World Moderator(s): Ching-Yu Cheng (National University of Singapore) and Pirro Hysi (King's College London) 11:00 AM - 12:45 PM; 615-617 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM 11:00 AM - 11:15 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM View Session Details 1733. The Consortium for Refractive Error and Myopia (CREAM) Identifies Four New Loci for Ocular Axial Length and Demonstrates Shared Loci for Axial Length and Refractive Error through Genome-Wide Association Studies Ching-Yu Cheng; Maria Schache; Mohammad K. Ikram; Jeremy A. Guggenheim; Dwight Stambolian; Caroline C. Klaver; Yik-Ying Teo; Seang-Mei Saw; Paul N. Baird View Presentation 1734. Heritability Estimation of Axial Length and Refractive Error Explained by GenomeWide Single Nucleotide Polymorphisms Masahiro Miyake; Kenji Yamashiro; Hideo Nakanishi; Isao Nakata; Yumiko AkagiKurashige; Kyoko Kumagai; Akitaka Tsujikawa; Ryo Yamada; Fumihiko Matsuda; Nagahisa Yoshimura View Presentation 1735. Meta-analysis of functional enrichment results from five GWAS studies reveals biological processes involved in human refractive variation Robert Wojciechowski; Konrad Oexle; Claire L. Simpson; Joan E. Bailey-Wilson; Jugnoo S. Rahi; Christopher J. Hammond; Dwight Stambolian; Pirro G. Hysi View Presentation 1736. Genome-wide Meta-Analyses Of Multi-Ethnic Cohorts Identify Multiple New Susceptibility Loci For Refractive Error And Myopia Virginie J. Verhoeven; Pirro G. Hysi; Robert Wojciechowski; Jeremy A. Guggenheim; Seang-Mei Saw; Joan E. Bailey-Wilson; Dwight Stambolian; Caroline C. Klaver; Christopher J. Hammond View Presentation 1737. International meta-analysis of genetic factors influencing intraocular pressure: the International Glaucoma Genetics Consortium Study Pirro G. Hysi; Ching-Yu Cheng; Tin Aung; Jamie E. Craig; Christopher J. Hammond; Andrew J. Lotery; Norbert Pfeiffer; Cornelia M. van Duijn; Ananth C. Viswanathan; Janey L. Wiggs View Presentation 1738. An International Genome-Wide Association Study of Glaucoma-Related Optic Disc Parameters in 18,000 Caucasians: the International Glaucoma Genetics Consortium Henriet Springelkamp; Rene Hoehn; Christopher J. Hammond; Alex W. Hewitt; Caroline C. Klaver; Stuart MacGregor; David A. Mackey; Paul Mitchell; Tien Y. Wong; Cornelia M. van Duijn View Presentation 1739. Methylation landscape of ocular tissue and their correlation to peripheral leucocytes Alex W. Hewitt; Jihoon E. Joo; Jie Wang; Jamie E. Craig; Richard Saffery View Presentation 246. Cone Photoreceptors in Aging and Disease Moderator(s): Mark Pennesi (Casey Eye Institute - OHSU) and Ann Elsner (Indiana University) 11:00 AM - 12:45 PM; TCC LL 4/5 AM View Session Details View Session Details 1740. Cone Distribution Variations for Young Healthy Subjects vs. Older Subjects Ann E. Elsner; Toco Y. Chui; Lei Feng; Colleen M. McIntyre; Hongxin Song; Thomas Gast; Stephen A. Burns View Presentation 1741. Longitudinal Cone Density Measurements using a Commercially Available FloodIlluminated Adaptive Optics Camera in Japanese Macaque Monkeys with Dominantly Inherited Drusen Mark E. Pennesi; Keith V. Michaels; Shu Feng; Travis B. Smith; Anupam K. Garg; Trevor J. McGill; Laurie Renner; Marvin Sperling; Kay D. Rittenhouse; Martha Neuringer View Presentation 1742. Assessing the Mosaic of Cone Photoreceptors Overlying Subretinal Drusenoid Deposits in vivo Using Adaptive Optics Sarah Mrejen; Taku Sato; Richard F. Spaide View Presentation 1743. Adaptive Optics Scanning Laser Ophthalmoscopy in Stargardt Disease Reveals Decreased Cone and Rod Densities Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 79 sur 222 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM Hongxin Song; Angela Pugliese; Ethan A. Rossi; Lisa R. Latchney; Edwin M. Stone; Alfredo Dubra; Jennifer J. Hunter; Mina M. Chung View Presentation 1744. Cone structure imaged with Adaptive Optics Scanning Laser Ophthalmoscopy in eyes with Non-Neovascular Age-related Macular Degeneration Shiri Zayit-Soudry; Reema Syed; Kavitha Ratnam; Moreno Menghini; Austin Roorda; Jacque L. Duncan View Presentation 1745. Adaptive Optics Imaging of Photoreceptors following Repair of Rhegmatogenous Retinal Detachments Meenakashi Gupta; Michael Dubow; Alexander Pinhas; Nishit Shah; Patricia Garcia; Gennady Landa; Yusufu N. Sulai; Alfredo Dubra; Richard B. Rosen View Presentation 1746. Changes in Cone Reflectivity and Regularity Assessed by Adaptive Optics Scanning Laser Ophthalmoscopy (AOSLO) Correlate with Presence of Diabetic Retinopathy Jan Lammer; Amel Ahmed; Sonja G. Prager; Michael C. Cheney; Stephen A. Burns; Paolo S. Silva; Lloyd P. Aiello; Jennifer K. Sun View Presentation 247. Surgery: Non-Refractive and Keratoprothesis Moderator(s): Frank Larkin (Moorfields Eye Hospital), Mark Terry (Devers Eye Institute) and Sanjay Patel (Mayo Clinic) 11:00 AM - 12:45 PM; TCC 303 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM View Session Details 1747. Microstructural analysis of the cornea after Descemet membrane endothelial keratoplasty using in vivo confocal microscopy Akira Kobayashi; Hideaki Yokogawa; Natsuko Yamazaki; Toshinori Masaki; Kazuhisa Sugiyama View Presentation 1748. Impact of Donor Age on Endothelium-Descemet Membrane Layer Harvesting and Roll Formation Adam Bennett; Shahira Rashad; Donna Drury; H D. Cavanagh; James P. McCulley; Matthew Petroll; Vinod V. Mootha View Presentation 1749. Descemet’s Stripping Automated Endothelial Keratoplasty (DSAEK) vs Ultra-Thin DSAEK (UT-DSAEK) vs Descemet’s Membrane Endothelial Keratoplasty (DMEK) Peng Yan; Salina Teja; Kashif Baig View Presentation 1750. Diamond knife assisted Deep Anterior Lamellar Keratoplasty (Dia-DALK): A new surgical technique for management of Keratoconus Rasik B. Vajpayee; Prafulla K. Maharana; Namrata Sharma View Presentation 1751. Femtosecond Laser-Assisted Deep Anterior Lamellar Keratoplasty with Zig-zag Configuration: Initial Outcomes Ijeoma Asota; Matthew Wade; John Xie; Sumit Garg; Roger F. Steinert; Marjan Farid View Presentation 1752. Corneal Endothelial Cell Loss after Endothelial and Penetrating Keratoplasty for Endothelial Disease Sanjay V. Patel; Keith H. Baratz; Jay W. McLaren; Lori A. Bachman; William M. Bourne View Presentation 1753. Outcomes of new partial-thickness corneal grafts: a paradigm shift in practice, but at what cost Richard A. Mills; Miriam C. Keane; Keryn Williams View Presentation 248. Synaptic Mechanisms, Ion Channels and Gap Junctions Moderator(s): Jeff Diamond (NINDS) and Steven Barnes (Dalhousie University-DAL11762) 11:00 AM - 12:45 PM; TCC 304 View Session Details Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary 11:00 AM - 11:00 Kemmler has been added Include in Itinerary 11:00 AM - 11:15 1754. Tiered cross-class bipolar cell gap junctional coupling in the rabbit retina J Scott Lauritzen; John V. Hoang; Crystal L. Sigulinsky; Bryan W. Jones; James R. Anderson; Carl B. Watt; Shoeb Mohammed; Robert E. Marc View Presentation 1755. Properties of release from rods revealed by visualizing individual synaptic vesicles Minghui Chen; Matthew J. Van Hook; David Zenisek; Wallace B. Thoreson View Presentation 1756. Photoreceptor Synaptic Rbbon Plasticity and Its Impact on the Size and Frequency of Miniature-like Postsynaptic Currents in the Hibernating Grund Squirrel Retina Wei Li; Shan Chen View Presentation 1757. Calmodulin regulates vesicle replenishment and shapes kinetics of synaptic transfer from cones Matthew J. Van Hook; Wallace B. Thoreson View Presentation 1758. The kinetic properties of negative feedback from horizontal cells to cones Maarten Kamermans; Rozan Vroman; Lauw Klaassen; Trijntje Sjoerdsma; Robert G. Smith; Marcus H. Howlett View Presentation 1759. Synaptic interactions in the outer retina of the mouse Robin Kemmler; Thomas Euler; Timm Schubert View Presentation 1760. An interaction between parallel circuits alters the state of a synapse and the retinal representation of visual space Greg Schwartz; William Grimes; Fred Rieke View Presentation Include in Itinerary AM AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM 249. Nanotechnology and Regenerative Medicine Moderator(s): David Pepperberg (Univ of Illinois at Chicago) and Rajiv Mohan (University of Missouri-Columbia) 11:00 AM - 12:45 PM; TCC 305 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM View Session Details 1761. Potentiation of bipolar cell GABAA receptors by a photo-isomerizable compound Lan Yue; Michal Pawlowski; Karol S. Bruzik; David R. Pepperberg View Presentation 1762. Insulin-like Growth Factor Binding Protein-like 1 (IGFBPL1) as a Potent Regulator of Optic Nerve Regeneration Chenying Guo; Kin-Sang Cho; Kissaou T. Tchedre; Jie Ma; Christian Antolik; Dong F. Chen View Presentation 1763. Subretinal Implantation of Gelatin Films with Stem Cells Derived RPE in Rats Yuntao Hu; Kenrick Kuwahara; Padmaja B. Thomas; Bruno Diniz; Ramiro Ribeiro; Ashish K. Ahuja; Sherry T. Hikita; Lincoln V. Johnson; Biju B. Thomas; Mark S. Humayun View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 80 sur 222 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM 1764. RPE for photoreceptor regeneration in mouse eye Shu-Zhen Wang; Run-Tao Yan View Presentation 1765. Conjugation of antibody on biocompatible nanoparticles for targeted drug delivery Jin Zhang; Wai Hei Tse; William G. Hodge View Presentation 1766. Face Detection using the Argus® II Retinal Prosthesis System Paulo E. Stanga; Jose A. Sahel; Saddek Mohand-Said; Lyndon daCruz; Avi Caspi; Francesco Merlini; Robert J. Greenberg View Presentation 1767. Transfer characteristics of electronic subretinal implants measured by electrically evoked corneal potentials Katarina Stingl; Karl-Ulrich Bartz-Schmidt; Dorothea Besch; Angelika Braun; Florian Gekeler; Udo Greppmaier; Andreas Schatz; Eberhart Zrenner View Presentation 250. Oxidative/ER Stress and Autophagy in RPE and Retina Moderator(s): William Gordon (LSU Health Sciences Center) and Ryan Thummel (Wayne State Univ School of Med) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM View Session Details 1768 - A0114. Photobiomodulation by 670nm light protects against oxidative stress in multiple organs in a rodent model of diabetes mellitus Johnny Tang; Yunpeng Du; Jinwhan Lim; Sandeep Gopalakrishnan; Janis T. Eells; Diane Henshel; John B. Watkins; Timothy S. Kern View Presentation 1769 - A0115. Effect of UVB irradiation on inhibitor of apoptosis proteins(IAPs) in apoptotic retinal pigment epithelial cell lines LIN LU View Presentation 1770 - A0116. Testing the effect of RPE barrier function regulators in vitro and in vivo Meili Zhu; Yun-Zheng Le View Presentation 1771 - A0117. Effect of Cfh on the response to acute subretinal oxidative stress xiao chen; Bogale Aredo; Rafael Ufret-Vincenty View Presentation 1772 - A0118. Modulating inflammation in retina through targeting of GPR109A: Novel implications for therapeutic management of diabetic retinopathy Deeksha Gambhir; Rajalakshmi Veeranan-Karmegam; Amany M. Tawfik; Sylvia B. Smith; Vadivel Ganapathy; Pamela M. Martin View Presentation 1773 - A0119. Photoreceptor outer segment phagocytosis couples lysosome biogenesis to autophagy in the retinal pigment epithelium Jin Xu; Kimberly A. Toops; Aparna Lakkaraju View Presentation 1774 - A0120. Absence of Neural Cell Adhesion Molecule (NCAM) influences injured retinal cell survival Po-shan Margaret Luke; Terry L. LeVatte; David B. Clarke View Presentation 1775 - A0121. P23H-Light Induced Retinal Degeneration occurs via cell death with autophagy in a Xenopus laevis Model of Retinitis Pigmentosa Tami P. Bogea; Beatrice M. Tam; Orson L. Moritz View Presentation 1776 - A0122. Rapid photoreceptor degeneration in the area centralis and visual streak of Rpe65-deficient dogs: morphologic and histologic characterization Freya M. Mowat; Laurence M. Occelli; Kristen J. Gervais; Matthew J. Annear; Joshua T. Bartoe; Anastasios Georgiadis; James W. Bainbridge; Robin R. Ali; Simon M. PetersenJones View Presentation 1777 - A0123. The Role Of Tlr4 In Retinal Ganglion Cell Death After Ischemia Andrea Rachelle C. Santos; Galina Dvoriantchikova; Eleut P. Hernandez; Dmitry V. Ivanov View Presentation 1778 - A0124. Catch-up phenomenon in drusenoid pigment epithelium detachment and acquired vitelliform lesions in AMD Rosa Dolz-Marco; Roberto Gallego-Pinazo View Presentation 1779 - A0125. Molecular events for Bax activation in retinal cell death induced by alltrans-retinal Osamu Sawada; Akiko Maeda; Shigemi Matsuyama; Tadao Maeda View Presentation 1780 - A0126. Adult human RPE has greater susceptibility to IL17A-induced degeneration than fetal human RPE Xi K. Chu; Yujuan Wang; De Fen Shen; Alexander J. Ogilvy; Rong Li; Shayma Jawad; Baoying Liu; Mones S. Abu-Asab; Jingsheng Tuo; Chi-Chao Chan View Presentation 1781 - A0127. Evidence for baseline abnormalities in the retinal vascular network of Trp1-Cre mice Aristomenis Thanos; Ahmad Al Moujahed; Lucy H. Young; Demetrios Vavvas View Presentation 1782 - A0128. Extranuclear DNA: a Normal Phenomenon or an Indication of Pathology? Alexander J. Ogilvy; De Fen Shen; Yujuan Wang; Chi-Chao Chan; Mones S. Abu-Asab View Presentation 1783 - A0129. Redox Proteomic Identification of Molecules in Retinal Endothelial Cells Undergoing Disulfide Reduction as a Result of Radiation Megan E. Crowe; Christopher Lieven; Leonard A. Levin View Presentation 1784 - A0130. Metabolite profiling of the neuroprotective phosphine-borane complex PB1 Christopher Lieven; Leonard A. Levin View Presentation 1785 - A0131. Alcohol exposure induces toxicity in a human RPE model Francisco J. Romero; Miguel Flores-Bellver; Luis Bonet-Ponce; Natalia Martinez-Gil; Jorge M. Barcia; Siv Johnsen-Soriano; Emma Arnal View Presentation 1786 - A0132. βA3/A1-crystallin is essential for lysosome-mediated waste clearance in retinal pigmented epithelial (RPE) cells Mallika Valapala; Christine M. Wilson; Imran A. Bhutto; Stacey L. Hose; Seth Greenbaum; Rhonda Grebe; James T. Handa; Lijin Dong; Eric F. Wawrousek; Debasish Sinha View Presentation 1787 - A0133. Progesterone Administration Decreases Glutamate Concentration In The Retina Of An Animal Model Of Retinitis Pigmentosa Violeta Sanchez-vallejo; Soledad Benlloch-Navarro; Raquel Álvarez-Nölting; Francisco J. Romero; Maria Miranda View Presentation 1788 - A0134. Retinal Glutathione And Glutamate Alterations In The Rd10 Mice Maria Miranda; Soledad Benlloch-Navarro; Violeta Sanchez-vallejo; Miguel FloresBellver; Jose M. Soria; Javier J. Araiz View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 81 sur 222 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 1789 - A0135. CCR2-expressing bone marrow derived cells promote retinal inflammation in a mouse model of uveitis Feeling Yu Ting Chen; Delu Zhou; Todd C. Metzger; Mark Anderson; Nancy A. McNamara View Presentation 1790 - A0136. High Throughput siRNA Screen to Identify Targets of RPE Cells Protection from 7-Ketocholesterol Induced Oxidative Damage Ji-Ye Wei; Jon E. Chatterton; Carl Romano; Kristina L. Rhoades View Presentation 1791 - A0137. Neuroprotectin D1 (NPD1) Reverses 15 Lipoxygenase-1 Inhibition of Oxidative Preconditioning in RPE cells Eric J. Knott; William C. Gordon; Nicolas G. Bazan View Presentation 1792 - A0138. Neuroprotectin D1 Mimics Preconditioning by Inducing RPE Cell Survival Against Subsequent Oxidative Stress William C. Gordon; Eric J. Knott; Nicolas G. Bazan View Presentation 1793 - A0139. DHA restores VEGF via Nrf2 protection pathway inhibiting oxidative damage in RPE at high glucose levels Siv Johnsen-Soriano; Emma Arnal; Miguel Flores-Bellver; Luis Bonet-Ponce; Francisco Javier Romero View Presentation 1794 - A0140. Docosahexaenoic Acid Bolsters Mild Oxidative Stress Preconditioning in Retinal Pigment Epithelial Cells Nicolas G. Bazan; William C. Gordon; Eric J. Knott View Presentation 1795 - A0141. Physicochemical evidence for oxidative modifications of human RPE melanin with aging and of bovine RPE melanin with in vitro photoaging Tadeusz J. Sarna; Anna K. Pilat; Andrzej Zadlo; Shosuke Ito; Kazumasa Wakamatsu; Grzegorz Szewczyk; Aaron Kittell; Theodore G. Camenisch; Janice M. Burke; Christine Skumatz View Presentation 1796 - A0142. PGC-1 isoforms regulate photoreceptor response to photo-oxidative stress: relevance to retinal degenerative diseases Jared Iacovelli; Zoltan Arany; Magali Saint-Geniez View Presentation 1797 - A0143. Protective effect of fenofibrate on oxidative stress induced retinal neuronal cell damage Ying-Jung Hsu; Sheng-Li Cho; Chang-Hao Yang View Presentation 1798 - A0144. Overexpression of OASIS/CREB3L1 in photoreceptor of zebrafish Induces Photoreceptor Cell Death without Classical Endoplasmic Reticulum Stress Response Yoshihito Oura; Motokazu Tsujikawa; Kohji Nishida View Presentation 1799 - A0145. Catechins attenuate sodium iodate-induced retinal degeneration Yaping Yang; Yongjie Qin; Yolanda Yip; Kai On Chu; Kwok Ping Chan; Chi Pui Pang; Sun On Chan View Presentation 1800 - A0146. Cigarette Smoke (CS) and Nrf2 Deficiency Induce Mitochondrial Dysfunction in Retinal Pigment Epithelial (RPE) Cells Marisol d. Cano; Brad Barnett; Lei Wang; Sonny E. Dike; James T. Handa View Presentation 1801 - A0147. Oxidative stress affects tight junction expression in Human retinal pigment epithelium Junko Hirata; Ji-Ae Ko; Hideki Mochizuki; Kunihiko Funaishi; Ken Yamane; Yoshiaki Kiuchi View Presentation 1802 - A0148. Mechanism of RPE cell death following activation of the NLRP3 inflammasome by lipofuscin photoreactivity Carolina Brandstetter; Lena K. Mohr; Frank G. Holz; Tim U. Krohne View Presentation 1803 - A0149. Activation of Rap1 prevents tumor necrosis factor alpha-induced ROS generation in RPE Haibo Wang; Manabu McCloskey; Erika S. Wittchen; M Elizabeth Hartnett View Presentation 1804 - A0150. Calpain Inhibition Following Retinal Detachment: A Way to Prolong Autophagy and Delay Apoptosis Nicholas D. Chinskey; Qiong D. Zheng; David N. Zacks View Presentation 1805 - A0151. Protective effect of TGF-b1 in RPE cells upon oxidative stress as a model for oxidative damage during dry AMD Zeev Dvashi; Ayala Pollack View Presentation 1806 - A0152. In the retinal mitochondrial oxidative stress NLRC4 inflammasome silencing attenuates photoreceptor pyroptosis Narsing A. Rao; Sindhu Saraswathy View Presentation 1807 - A0153. Aberrant Protein Trafficking Underlies Vision Defects in Syndromic Albinism Ryan Thummel; Xixia Luo; Alan Dombkowski; James Granneman View Presentation 1808 - A0154. ER stress involvement in photoreceptor death in tubby mice Xue Cai; James F. McGinnis View Presentation 1809 - A0155. Temperature-dependent response of retinal pigment epithelial cells to laser irradiation Ralf Brinkmann; Hisashi Iwami; Joachim Pruessner; Veit Danicke; Yoko Miura View Presentation 1810 - A0156. Receptor-Interacting Protein Kinases and the NLRP3 Inflammasome Mediate Tamoxifen Toxicity of the Retinal Pigment Epithelium Leo A. Kim; Dhanesh Amarnani; Wen A. Tseng; Demetrios Vavvas; Patricia A. D'Amore View Presentation 1811 - A0157. 7-Ketocholesterol induces cytokines through NF-κB activation and CHOP in ARPE-19 cells Jiahn-Dar Huang; Jung W. Lee; Ignacio R. Rodriguez View Presentation 1812 - A0158. Ethambutol-induced autophagy deregulation and cytotoxic effects in retinal ganglion cells Shun-Ping Huang; Shu-Fung Lin; Rong-Kung Tsai View Presentation 1813 - A0159. Circadian rhythm of basal autophagy and its regulation in the RPE Jingyu Yao; Lin Jia; Shameka Shelby; Anna Ganios; Debra A. Thompson; David N. Zacks View Presentation 251. Cataract Surgery II Moderator(s): Raffael Liegl (Ludwig-Maximilians-University Munich) 11:00 AM - 12:45 PM; Exhibit / Poster Hall View Session Details Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary 28/03/2013 Abstract Central Page 82 sur 222 11:00 AM - 12:45 PM Withdrawn 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 1814 - A0160. Does Music Influence Surgical Time in Routine Cataract Surgery? Sajjad Abbas View Presentation 1815. Comparison of Tissue Temperature in Sleeveless Microincision 1.1 mm and Conventional Coaxial Mini-Incision 2.4 mm Phacoemulsification Avner Belkin; Adi Abulafia; Shay Ofir; Adi Michaeli; Ehud I. Assia View Presentation 1816 - A0162. A Case of Lens Subluxation Associated with Congenital Cytomegalovirus Infection Risa Yamazaki; Takako Tachikawa; Tetsuko Mita; Daisuke Yuzurihara; Osamu Katsumi; Toru Noda View Presentation 1817 - A0163. From Accommodation Restoration to the Antioxidant Lens Sink: Theoretical Basis for Lenticular Refractive Surgery Raymond I. Myers; Suzanne R. Lakamp View Presentation 1818 - A0164. Evaluation of femtosecond laser-assisted clear cornea cataract surgery in lens exfoliation syndrome (LES) Anam Qureshi; A. John Kanellopoulos View Presentation 1819 - A0165. Increasing Incidence of Cataract Surgery: A Population-based Study Jay C. Erie; Heidrun Gollogly; David Hodge View Presentation 1820 - A0166. A Comparison of Biplanar Cataract Incision Postoperative Architecture Involving Malyugin Ring Insertion as Performed by a Resident Surgeon Solomon W. Ross; Bethany Markowitz View Presentation 1821 - A0167. Validation of a Virtual Cataract Surgery Simulator for Simulation-Based Medical Education Shameema Sikder; Abdullah M. Alfawaz; Jonathan Song; Pat Banerjee; Cristian j. Luciano; Jia Luo; Patrick Kania View Presentation 1822 - A0168. Exploration of a Circularly Polarized Femtosecond Laser Beam for Laser Cataract Application Anthony Dennison; Michael A. Campos; Mikhail Levin; Hong Fu View Presentation 1823 - A0169. Effect of numerical aperture of a femtosecond laser system on the required pulse energy for capsulotomy and lens fragmentation Michael A. Campos; Anthony Dennison; Hong Fu View Presentation 1824 - A0170. The effect of cataract on circadian phototentrainment Adam E. Brondsted; Birgitte Haargaard; Birgit A. Sander; Henrik Lund-Andersen; Poul Jennum; Steen Gammeltoft; Line Kessel View Presentation 1825 - A0171. Anesthesia Choice and Pain Control during Cataract Surgery Yuna Rapoport; Amy Chomsky; Laura L. Wayman View Presentation 1826 - A0172. Impact of intra-operative floppy iris and use of pupillary expansion devices on intra-operative complication rates in cataract surgery: results of the Ophthalmic Surgical Outcomes Data Project David E. Vollman; Amy Chomsky; Elizabeth Baze; Mary K. Daly; Mary G. Lawrence View Presentation 1827 - A0173. Analysis of corneal incisional structure in different incision size with or without stromal hydration in cataract surgery by using anterior segment optical coherence tomography Jonghyun Lee; Jong Wook Bang; Do Hyung Lee View Presentation 1828 - A0174. Wavefront Analysis Comparison Of Aspheric Versus Spherical Intraocular Lens Implantation In Cataract Surgery - A Meta-Analysis Alexander K. Schuster; Jonas Tesarz; Urs Vossmerbaeumer View Presentation 1829 - A0175. Rotational stability of a hydrophobic-acrylic aspheric toric intraocular lens Sanjeev Kasthurirangan; Don R. Nixon; Lucas Feuchter; Pamela Smith View Presentation 1830 - A0176. Refractive surgical outcomes of cataract surgeons in training Gokul Kumar; Aaron Y. Lee; Cecilia S. Lee View Presentation 1831 - A0177. The effect of a second 2.4mm keratome incision on reducing postoperative astigmatism in cataract surgery Riley Hall; Gunpreet Singh; Maurice Agha; Neil K. Wade View Presentation 1832 - A0178. Cataract Surgery with Intraocular Lens Implantation in Patients with Vogt Koyanagi Harada Syndrome Erika Miolet Hurtado Jallaza; Bernardo A. Schlaen; Cristobal A. Couto; Maria de las Mercedes Frick; Matilde Lopez View Presentation 1833 - A0179. Intraoperative Management of Crystalens Intraocular Lens Mojgan Hassanlou; Deepinder K. Dhaliwal View Presentation 1834 - A0180. Intraocular lens power prediction in eyes with prior radial keratotomy using Fourier-domain optical coherence tomography Emily Waisbren; Li Wang; Maolong Tang; Douglas D. Koch View Presentation 1835 - A0181. Comparison of cumulative dissipated energy, total phacoemulsification time, and visual acuity in the early post operative period following uncomplicated cataract extraction by resident surgeons with and without the use of intracameral preservative free epinephrine Benjamin A. Katz; Bethany Markowitz View Presentation 1836 - A0182. Phacoemulsification Parameters and Measures of Corneal Edema Melissa M. Wong; Anita Shukla; Wuqaas M. Munir View Presentation 1837 - A0183. Comparison of surgical results between intrascleral posterior chamber intraocular lens (PC-IOL) fixation and transscleral suturing of PC-IOL in eyes without capsular support Shunji Kusaka; Shohei Komoto; Akiko Fujii; Keiichi Aomatsu; Eiko Koike; Kuniko Tachibana; Shiro Higaki; Yoshikazu Shimomura View Presentation 1838 - A0184. Initial Resident Experience Performing Cataract Surgery with and without Femtosecond Laser Adam L. Prickett; Maria S. Cortina; Joshua H. Hou; Jose De la Cruz View Presentation 1839 - A0185. Does case order affect cataract surgery complication rates and case time? Parisa Taravati; Divakar Gupta; Leona Ding View Presentation 1840 - A0186. Ophthalmic Surgery Simulator Training Improves Resident Performance of Capsulorhexes in the Operating Room David C. Reed; Darin R. Goldman; Colin A. McCannel View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 83 sur 222 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 1841 - A0187. Model of Plasma Characteristics across the Anterior Lens and Aqueous Boundary Richard T. Olmstead View Presentation 1842 - A0188. A Possible Root Cause for Incomplete Cornea Incision in a Femtosecond Laser Cataract Surgery Hong Fu View Presentation 1843 - A0189. Combined phacoemulsification, primary IOL implantation and pars plana vitrectomy in children with uveitis Madeleine Zetterberg; Sara Pålsson; Marita A. Gronlund; Alf Nyström View Presentation 1844 - A0190. Forward Light Scatter, Modulation Transfer Function and Image Quality Measurements for AcrySof Natural Intraocular Lenses Kamal Das; Jim Schwiegerling; Mutlu Karakelle; John Stover; Marcia Ong View Presentation 1845 - A0191. Posterior iris-claw aphakic intraocular lens implantation in children Johannes Gonnermann; Necip Torun; Matthias Klamann; Anna-Karina B. Maier; Peter Rieck; Eckart Bertelmann View Presentation 1846 - A0192. Performance of a new preloaded insertion system for a 1-piece hydrophobic-acrylic, aspheric intraocular lens Steven Anderson; Lucas Feuchter; Roland Pohl; Michael Amon; Oliver Findl; Gandolf Sauder View Presentation 1847 - A0193. Intraoperative and perioperative OCT findings of cataract surgery Richard Gans; Justis P. Ehlers; William J. Dupps; Gina M. Smith; Peter K. Kaiser; Sunil K. Srivastava View Presentation 1848 - A0194. Refractive Outcomes of Toric Intraocular Lens Implantation for Correction of Astigmatism During Cataract Surgery Naveen K. Rao; Amal Althawabi; Kirstin L. Tawse; Sarkis H. Soukiasian View Presentation 1849 - A0195. Comparison of Biplanar Cataract Incision Postoperative Architecture With and Without Wound Suture as Performed by a Resident Surgeon Michelle A. Overturf; Solomon W. Ross; Bethany Markowitz View Presentation 252. Lasers; Structure and Function I Moderator(s): Carlo Enrico Traverso (Eye Clinic) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM View Session Details 1850 - B0104. Narrower Angles Are Associated with Greater Angle Opening After Laser Peripheral Iridotomy Roland Y. Lee; Toshimitsu Kasuga; Qi N. Cui; Shan C. Lin View Presentation 1851 - B0105. Comparison of fluctuations of intraocular pressure before and after selective laser trabeculoplasty in normal tension glaucoma Naoki Tojo; Keiichi Mitarai; Miyako Oka; Akio Miyakoshi; Atsushi Hayashi View Presentation 1852 - B0106. Diode Cyclophotocoagulation for the Treatment of Refractory Childhood Glaucomas Lekha Ravindraraj; Sumana S. Kommana; Robert D. Fechtner; Albert S. Khouri View Presentation 1853 - B0107. Change in Intraocular Pressure and Angle of Eyes with Primary Angle Closure Suspects One Year after Laser Peripheral Iridotomy Dapeng Mou View Presentation 1854 - B0108. The influence of treatment settings for SLT and ALT in the management of open angle glaucoma (OAG): a systematic review and meta-analysis Sourabh Arora; Karim F. Damji; Ezekiel Weis View Presentation 1855 - B0109. Intraocular Pressure Spikes following Sequential Laser Peripheral Iridotomy for Angle Closure Jamie Ng; Tian Loon Lee; Monisha E. Nongpiur; Wai-Jia Tan; Tin Aung; Shamira Perera View Presentation 1856 - B0110. Predictors of Short-Term Intraocular Pressure Response to Selective Laser Trabeculoplasty in Afro-Caribbeans with Glaucoma Tony Realini View Presentation 1857 - B0111. Longitudinal evaluation of selective laser trabeculoplasty repeatability in eyes with pseudoexfoliation glaucoma Ernesto D. Golez; Mark A. Latina View Presentation 1858 - B0112. Predictors of Failure with Transscleral Diode Laser Cyclophotocoagulation in the Treatment of Refractory Glaucoma Samantha Dewundara; Bret A. Hughes; Rominder Momi; Justin Tannir; Chaesik Kim View Presentation 1859 - B0113. The Relationships between Immediate and Short-term Intra-ocular Pressure (IOP) Following Selective Laser Trabeculoplasty (SLT), Trabecular Meshwork Pigmentation (TMP), and Laser Power Used Yotam Weiner; Asher Weiner View Presentation 1860 - B0114. Aqueous production reduction and aqueous outflow increase in rabbit eyes after ultrasonic cyclocoagulation Aurelie Begle; Florent Aptel; Cyril Lafon; Jean-Yves Chapelon; Fabrice Romano View Presentation 1861 - B0115. Comparison of argon laser trabeculoplasty and selective laser trabeculoplasty: a meta-analysis Audrey M. Paulo; Lalatiana H. Razafindrabe; Marie-Josee Fredette View Presentation 1862 - B0116. Selective Laser Trabeculoplasty in the Treatment of Glaucoma in Phakic Versus Pseudophakic Patients Neil Kalbag; Shriji Patel; Albert S. Khouri; Tamara L. Berezina; Robert D. Fechtner; Amir Cohen View Presentation 1863 - B0117. Trans-scleral Selective Laser Trabeculoplasty (SLT) Without a Gonioscopy Lens Michael Belkin; Noa Geffen; Shay Ofir; Audrey Kaplan Messas; yaniv barkana; Avner Belkin; Ehud I. Assia View Presentation 1864 - B0118. Resident-Performed Selective Laser Trabeculoplasty in Open Angle Glaucoma Patients Eugene Lowry; Daniel Greninger; Travis Porco; Ayman Naseri; Robert L. Stamper; Ying Han View Presentation 1865 - B0119. The effect of Selective Laser Trabeculoplasty on IOP changes in the contralateral eye over a two-year followup Sonia Rana; Justin Tannir; Bret A. Hughes View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 84 sur 222 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 1866 - B0120. Assessment of the Long-Term Outcome of Selective Laser Trabeculoplasty (SLT) in Treatment of Different Glaucoma Types in Patients Receiving Maximum Medicinal Treatment Eman Elhawy; Camila Zangalli; Daniel M. Shapiro; Lalita Gupta; Michael Hsieh; Abigail Kasprenski ; L Jay Katz; George L. Spaeth View Presentation 1867 - B0121. Patterned Laser Trabeculoplasty with PASCAL streamline 577 Miho Nozaki; Shuichiro Hirahara; Yuichiro Ogura View Presentation 1868 - B0122. Comparison of Selective Laser Trabeculoplasty Outcomes Between Physicians-in-Training and Attending Physicians Wanda Hu; Simon K. Law; JoAnn A. Giaconi View Presentation 1869 - B0123. Outcome of Combined Phacoemulsification and Endocyclophotocoagulation in Glaucoma Faisal A. AlMobarak View Presentation 1870 - B0124. Laser trabeculoplasty in primates: a morphometric analysis Tina Damarjian; Yang Sun; Vincent Gattone View Presentation 1871 - B0125. Long Term Effectiveness and Complications associated with LPI in Treatment of Acute Angle Closure Alicia Menezes; Sonya B. Shah; Eman Elhawy; Bruno M. Faria; Tao Ming Thomas Chia; Lan Lu; L Jay Katz View Presentation 1872 - B0126. Efficacy of Repeat Selective Laser Trabeculoplasty in African American Patients Mamta Shah; Babak Eliassi-Rad View Presentation 1873 - B0127. Effect of Pre-operative Medications on Selective Laser Trabeculoplasty Outcomes Babak Eliassi-Rad; Mamta Shah View Presentation 1874 - B0128. Plateau Iris among American Caucasians, American Chinese, and Mainland Chinese YINGJIE LI; Ye Elaine Wang; Mary Qiu; Dandan Wang; Mingguang He; Shan C. Lin View Presentation 1875 - B0129. Dynamic iris volume characteristics pre and post laser peripheral iridotomy (LPI) in eyes with occludable anterior chamber angles measured with 3 dimensional swept-source Ocular Coherence Tomography (OCT): The Investigating Management of Angle Closure and Treatment (IMPACT) study Rupert R. Bourne; Laura Sanchez Parra; Humma Shahid; Roger Buckley; Shahina Pardhan View Presentation 1876 - B0130. Corneal sensitivity and morphology of the corneal subbasal nerve plexus in primary congenital glaucoma Zisis Gatzioufas; Farhad Hafezi; Berthold Seitz View Presentation 1877 - B0131. Structural and Functional Changes after lntraocular Pressure Reduction in Patients with Glaucoma Michael Waisbourd; Jeanne Molineaux; Thandeka Myeni; George L. Spaeth; L Jay Katz View Presentation 1878 - B0132. Classification of Retinal Ganglion Cell Defects Seen on FrequencyDomain OCT in the Macula of Patients with Glaucoma Anastasia Slobodnick; Ali S. Raza; C. Gustavo De Moraes; Christopher C. Teng; Robert Ritch; Donald C. Hood View Presentation 1879 - B0133. The investigation of correlation between subfoveal choroidal thickness and sensitivity of visual field in highly myopic glaucoma with peripapillary atrophy optic disc Kazunori Tamaki; Itaru Kimura; Yutaka Imamura; Yugo Nakazawa; Satoshi Watanabe; Akira Murakami; Nobuyuki Ebihara View Presentation 1880 - B0134. Structure-Function Relationship between Spectral Domain Optical Coherence Tomography ,Heidelberg Retina Tomograph and Flicker Defined Form Perimetry in Patients with Ocular Hypertension and Preperimetric Glaucoma Ermengarda Marziani; Laura de Polo; Erma Collaku; Elena Weiszberger; Alessandra Acquistapace; Andrea Giani; Mirella Blini; Giovanni Staurenghi View Presentation 1881 - B0135. Nailfold Hemorrhages and Primary Open-Angle Glaucoma: More than What Meets the Eye Kevin Skuran; Ryan McCarty; Algis Grybauskas; Paulius Kuprys; John R. Samples; Paul A. Knepper View Presentation 1882 - B0136. Structure Function Relationship: ganglion cell complex assessment by two SD-OCT and standard automated perimetry Hussam El Chehab; Maxime Delbarre; Redouane Messaoudi; Jean-Remi Fenolland; Marechal Marie; Marlene Francoz; Jean-Marie Giraud; Frank May; Jean-Paul G. Renard View Presentation 1883 - B0137. Structure-Function Mapping: Conviction and Variability in Tracing of Retinal Nerve Fibre Bundles and Comparison to a Computational Model Jonathan Denniss; Andrew Turpin; Fumi Tanabe; Chota Matsumoto; Allison M. McKendrick View Presentation 1884 - B0138. Autoregressive Mixed Effects Approach for Modeling Longitudinal Standard Automated Perimetry Data in Glaucoma Manoj Pathak; Shaban Demirel; Stuart K. Gardiner View Presentation 1885 - B0139. Signal-to-Noise Ratios for Structural and Functional Tests in Glaucoma Cindy L. Blachly; Stuart K. Gardiner; Brad Fortune; Deborah Goren; Michael D. Whitworth; Steven L. Mansberger; Shaban Demirel View Presentation 1886 - B0140. Detectability of Visual Field Defects using 0.5 Degree Interval in High Resolution Perimetry and OCT Findings Takuya Numata; Chota Matsumoto; Sachiko Okuyama; Sonoko Takada; Fumi Tanabe; Shigeki Hashimoto; Mariko Eura; Tomoyasu Kayazawa; Eiko Koike; Yoshikazu Shimomura View Presentation 1887 - B0141. The Combined Structure and Function Index as a Predictor of Glaucoma Development Daniel Meira-Freitas; Renato Lisboa; Andrew J. Tatham; Linda M. Zangwill; Robert N. Weinreb; Christopher A. Girkin; Jeffrey M. Liebmann; Tammy T. Kuang; Christopher Bowd; Felipe A. Medeiros View Presentation 1888 - B0142. Reproducibility of In Vivo Laminar and Pre-laminar Tissues Measurements with Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography Vitor G. Prado; Paula d. Silva; Paula D. Borba; Igor Matsubara; Augusto Paranhos; Roberto M. Vessani; Tiago S. Prata View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 85 sur 222 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 1889 - B0143. The Impact of Lens Vault on Visual Acuity and Refractive Error in Subjects with Angle Closure Shweta Singhal; Stephen Stewart; Monisha E. Nongpiur; Hla M. Htoon; Shamira Perera; Tin Aung View Presentation 1890 - B0144. The optic nerve head: does size matter? Barbara Zangerl; Elizabeth Y. Wong; Nayuta Yoshioka; Michael P. Hennessy ; Michael Kalloniatis View Presentation 1891 - B0145. Predicting standard automated perimetry (SAP) sensitivities from spectral domain optical coherence tomography (SD-OCT) retinal nerve fiber layer thickness (RNFLT) using temporally correlated data Lisha Deng; Deborah Goren; Manoj Pathak; Shaban Demirel; Stuart K. Gardiner View Presentation 1892 - B0146. OPTIC NERVE AND LATERAL GENICULATE BODY IN GLAUCOMA AND ITS ASSOCIATION WITH FUNCTIONAL AN STRUCTURAL OCULAR ALTERATIONS Augusto Paranhos; Rafael L. Furlanetto; Sergio H. Teixeira; Claudio L. Lottenberg; Daniela B. Almeida-Freitas; Edson Amaro View Presentation 1893 - B0147. Relationship Between Relative Afferent Pupillary Defect with Pupillography and Ganglion Cell Complex Thickness by Optical Coherence Tomography in Asymmetric Glaucoma Naoki Ozeki; Kenya Yuki; Daisuke Shiba; Kazuo Tsubota View Presentation 1894 - B0148. Retinotopic-specific changes of cerebral blood flow and grey matter density in visual cortex of patients with glaucoma Zhang Shaodan; Bo Wang; Yuan Xie; Chun Zhang; Ningli Wang View Presentation 1895 - B0149. Dynamic iris volume characteristics in the physiological range of pupil size and reproducibility of measurements in eyes with occludable anterior chamber angles: The Investigating Management of Angle Closure and Treatment (IMPACT) study Humma Shahid; Laura Sanchez Parra; Roger Buckley; Shahina Pardhan; Rupert R. Bourne View Presentation 1896 - B0150. Comparison of optic disc parameters obtained by simultaneous stereo fundus photography and spectral domain optical coherence tomography Aiko Iwase; Toshiaki Nakagawa; Makoto Araie View Presentation 1897 - B0151. Stereometric parameters of optic disc. Comparison between the Heildelberg Retina Tomograph and Three-Dimensional Optical Coherence Tomography Claudia Castillo Ayometzi; Francisco Ortega Santana; Alfonso García López View Presentation 1898 - B0152. Longitudinal Analysis of Glaucoma Progression by Structure and Function: 7-year Follow-Up by Visual Field (VF) and Optical Coherence Tomography (OCT) Igor I. Bussel; Gadi Wollstein; Richard A. Bilonick; Yun Ling; Hiroshi Ishikawa; Jessica E. Nevins; Larry Kagemann; Jay S. Duker; Cynthia Mattox; Joel S. Schuman View Presentation 1899 - B0153. Use of Optical Coherence Tomography in Clinical Practice: Does it Influence the Diagnostic Decision of Glaucoma Specialists and Non-specialists? Carlos E. Barbosa; Luis G. Biteli; Roberto M. Vessani; Mauro T. Leite; Augusto Paranhos; Tiago S. Prata View Presentation 1900 - B0154. Bayesian Hierarchical Modelling of Longitudinal Visual Fields to Quantify Glaucoma Progression Susan R. Bryan; Koenraad A. Vermeer; Paul H. Eilers; Hans G. Lemij; Emmanuel Lesaffre View Presentation 1901 - B0155. Effect of ocular curvature and myopia on retinal blood flow: a theoretical study Andrea Dziubek; Giovanna Guidoboni; Anil N. Hirani; Alon Harris View Presentation 1902 - B0156. Relationship between the macular ganglion cell complex thickness and standard automated perimetry in glaucoma Antonio Ferreras; Blanca Monsalve; Pilar Calvo; Ana B. Pajarin; Paolo Frezzotti; Paolo Fogagnolo; Michele Figus; Michele M. Iester View Presentation 1903 - B0157. Does Cerebrospinal Fluid Communicate with the Eye? Emily Mathieu; Neeru Gupta; R. Loch Macdonald; Jinglu Ai; Yeni H. Yucel View Presentation 253. Myopia I, AP Moderator(s): Thomas Norton (University of Alabama at Birmingham) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM View Session Details 1904 - B0271. The effect of horizontal eye movements on changes in central refraction Arne Ohlendorf; Julia Gehrmann; Rainer E. Sessner View Presentation 1905 - B0272. Prognostic factors associated with pathological myopia in young patients with high myopia Tae Yokoi; Muka Moriyama; Noriaki Shimada; Natsuko Nagaoka; Kaori Kasahara; Kosei Shinohara; Yuichiro Tanaka; Yuichiro Kaneko; Takashi Tokoro; Kyoko Ohno-Matsui View Presentation 1906 - B0273. Axial Length and its Associations in an Adult Japanese Population: The Funagata Study Akira Sugano; Yusuke Tanabe; Koko Saito; Kei Homma; Ryo Kawasaki; Takeo Kato; Takamasa Kayama; Hidetoshi Yamashita View Presentation 1907 - B0274. Outer nuclear layer and retinal layer ratios in myopic and emmetropic populations using spectral domain optical coherence tomography Christopher A. Clark; Ann E. Elsner; Benjamin Konynenbelt; Joel A. Papay; Toco Y. Chui View Presentation 1908 - B0275. Extended Clinical Phenotype of Dome-Shaped Macula Marie-Helene Errera; Michel Michaelides; Pearse A. Keane; Anthony T. Moore; Jonathan Yeoh; Derek Chan ; Catherine A. Egan; Praveen J. Patel; Adnan Tufail View Presentation 1909 - B0276. Thinning of Lens Thickness Might Be Responsible for Myopia Development Ji C. He View Presentation 1910 - B0277. Increased Lens Opacities Associated with the Use of Topical Atropine for Myopia Retardation in Children Francine P. Yang; Fong Yee Foo; Seo Wei Leo View Presentation 1911 - B0278. Short-term adaptation of accommodative lag, facility and phoria in myopes fitted with multifocal contact lenses Jerome Ozkan; Ravi C. Bakaraju; Cathleen Fedtke; Jiyoon Chung; Klaus Ehrmann; Darrin Falk; Arthur Ho; Brien A. Holden View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 86 sur 222 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 1912 - B0279. Intraocular Pressure in Myopic Eyes during the Water Drinking Test Barbara M. Junghans; Chia-Jung Chang; Angela Siu; Natalia C. Soesanto; Megan F. Tu; Melanie J. Murphy; Sheila G. Crewther View Presentation 1913 - B0280. Optical coherence tomography-based evaluation of peripapillary tilting in highly myopic eyes Tomoko Asai; Yasushi Ikuno; Masahiro Akiba; Tsutomu Kikawa; Yukari Jo; Shinichi Usui; Kohji Nishida View Presentation 1914 - B0281. Contributions of Eye Power and Optical Eye Length to Emmetropization during Lens Induced Myopia and Recovery in the Chick Eye Zheng Shao; Kaitlin Bunghardt; Marsha L. Kisilak; Elizabeth L. Irving; Melanie C. Campbell View Presentation 1915 - B0282. Pattern ERG in chicks Lisa A. Ostrin; Christine F. Wildsoet View Presentation 1916 - B0283. Manual segmentation of choroidal volume in emmetropic and high myopic eyes Su-Na Lee; Giulio Barteselli; Sharif El-Emam; Huiyuan Hou; Dirk-Uwe G. Bartsch; Lingyun Cheng; William Freeman View Presentation 1917 - B0284. Strain differences in mouse lens refractive indices when measured with OCT Christopher C. Tan; Han na Park; Jacob G. Light; Kip Lacy; Machelle T. Pardue View Presentation 1918 - B0285. Isoflurane and lid retractors affect the optics of the chick eye Marsha L. Kisilak; Kaitlin Bunghardt; Vivian Choh; Elizabeth L. Irving; Melanie C. Campbell View Presentation 254. Strabismus/Eye Movements: Central and Peripheral Factors Moderator(s): Vallabh Das (University of Houston) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM View Session Details 1919 - B0316. Effect of oculomotor rehabilitation on vergence responsivity in mild traumatic brain injury (mTBI) Kenneth J. Ciuffreda; Preethi Thiagarajan View Presentation 1920 - B0317. Effect of oculomotor rehabilitation on basic versional eye movements and reading in mild traumatic brain injury (mTBI) Preethi Thiagarajan; Kenneth J. Ciuffreda; Diana P. Ludlam; Neera Kapoor; Jose E. Capo-Aponte View Presentation 1921 - B0318. Comparison of Smooth Pursuit and Saccadic Testing in Screening for Mild Traumatic Brain Injury Jonathan B. Jacobs; Margaret M. Skelly View Presentation 1922 - B0319. The Effect of Combat-Related Mild TBI on Saccadic Eye Movements Paul A. Wetzel; Ross C. Pallansch; George T. Gitchel; David X. Cifu View Presentation 1923 - B0320. Magnetic resonance imaging (MRI) features of partial or complete avulsion of the inferior rectus (IR) muscle Sylvia Yoo; Joseph L. Demer View Presentation 1924 - B0321. Three-dimensional magnetic resonance analysis of extraocular muscles demonstrates gaze-specific contractile shape changes Michelle Y. Peng; Robert B. Geary; Sarah Ying; David S. Zee; Peter Barker; Howard S. Ying View Presentation 1925 - B0322. Poisson Ratio Measurements of Extra-ocular Muscle and Tendon Andrew Shin; Lawrence Yoo; Joseph L. Demer View Presentation 1926 - B0323. Intra-sarcomeric Cytoskeleton and M-band Proteins in the Human Extraocular Muscles Adrihan H. Janbaz; Fatima Pedrosa Domellof View Presentation 1927 - B0324. Satellite cells in extraocular muscles of ALS patients Fatima Pedrosa Domellof; Mona M. Lindstrom; Anton Tjust View Presentation 1928 - B0325. Sources of tonic firing properties of saccade-related cerebellar neurons Adrienne Mueller; Ric Robinson View Presentation 1929 - B0326. Response properties of Frontal Eye Field (FEF) neurons during volitional smooth pursuit and optokinetic eye movements Leah Bakst; Lukas Brostek; Stefan Glasauer; Seiji Ono; Michael J. Mustari View Presentation 1930 - B0327. Electrical microstimulation of the deep superior colliculus (SC) in strabismic monkeys Jérome Fleuriet; Mark Walton; Seiji Ono; Michael J. Mustari View Presentation 1931 - B0328. Neural Mechanisms for smooth pursuit and vestibular ocular behavior in strabismic monkeys Michael J. Mustari; Seiji Ono View Presentation 1932 - B0329. Smooth pursuit adaptation in strabismic monkey with developmental esotropia Seiji Ono; Michael J. Mustari View Presentation 1933 - B0330. Comparison of Naso-Temporal Asymmetries in Optokinetic, SmoothPursuit and Ocular Following Eye Movements in Monkeys with Strabismus Anand C. Joshi; Mehmet N. Agaoglu; Ernest N. Baskin; Hope M. Queener; Vallabh E. Das View Presentation 1934 - B0331. Associations between central nervous system disorder and congenital esotropia Sjoukje E. Loudon; Jeroen Dudink; Liesbeth S. Smit; Jan Roelof Polling; Huibert J. Simonsz View Presentation 1935 - B0332. Niemann-Pick type C. An Expanding Spectrum of Ophthalmic Involvement Sophia Saleem; Steven A. Newman View Presentation 1936 - B0333. Orbital imaging in craniosynostosis: Understanding the pathophysiology of complex strabismus Maria Carolina Ortube; Federico G. Velez; Joseph L. Demer View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 87 sur 222 255. Retina/RPE: New Drugs, Mechanisms of Action, and Toxicity Moderator(s): Achim Krauss (GlaxoSmithKline) and Michele Reibaldi (University of Catania) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM View Session Details 1937 - C0151. Optimization of Cone-Directed AAV-Mediated Gene Augmentation Therapy for CNGB3-Achromatopsia by Use of the IRBP/GNAT2-Promoter and Intravitreal CNTF Administration Connie Y. Yeh; Simone Iwabe; Sanford L. Boye; Kendra McDaid; Christine Harman; Rong Wen; William W. Hauswirth; Andras M. Komaromy; Gustavo D. Aguirre View Presentation 1938 - C0152. Conversion to aflibercept for chronic refractory or recurrent neovascular age-related macular degeneration Yoshihiro Yonekawa; John B. Miller; John I. Loewenstein; Lucia Sobrin; Dean Eliott; Demetrios Vavvas; Joan W. Miller; Christopher M. Andreoli; Ivana K. Kim View Presentation 1939 - C0153. EFFECTIVE TARGETING OF THE PI3K/AKT/mTOR PATHWAY: A PROMISING THERAPEUTIC OPTION FOR THE TREATMENT OF OCULAR NEOVASCULARIZATION/INFLAMMATION/OEDEMA Temitope Sasore; Alison L. Reynolds; Breandan N. Kennedy View Presentation 1940 - C0154. Comparison of the toxicity of different drug delivery nanoparticles in RPE and photoreceptor cells Yueran Yan; Haijiang Lin; Hidetaka Matsumoto; Peggy Bouzika; Joan W. Miller; Demetrios Vavvas View Presentation 1941 - C0155. A Wnt Inhibitor for Treatment of Diabetic Retinopathy Danyang Chen; Erica Little View Presentation 1942 - C0156. Impact of Ocriplasmin Therapy in Symptomatic Vitreomacular Adhesion (VMA) Patients Considered to be Clinical Candidates for Vitrectomy Baruch D. Kuppermann View Presentation 1943 - C0157. SCHISANDRIN B IMPROVES THE VISUAL MOTOR RESPONSE AND PRESERVES PHOTORECEPTORS IN THE ZEBRAFISH PDE6C CONE DYSTROPHY MUTANT Yuk Fai Leung; Liyun Zhang; Leelyn Chong; Jin Cho; Kam Ming Ko View Presentation 1944 - C0158. Phase I, Randomized, Double-Masked, Vehicle-Controlled Study to Evaluate Safety, Tolerability and Pharmacokinetics of Recombinant Human Nerve Growth Factor Eye Drops in Healthy Volunteers Ronald R. Buggage; Pier A. Ruffini; Mauro P. Ferrari View Presentation 1945 - C0159. Antiglycating potential of procyanidin-B2 isolated from cinnamon bark: Prevention or treatment of diabetic ocular complications (cataract & retinopathy) G Bhanuprakash Reddy; Puppala Muthenna; Chandrasekhar Akileshwari; Ganugula Raghu; Palla Suryanarayana View Presentation 1946 - C0160. Effects of resveratrol, epigallocatechine gallate (EGCG) and curcumin on the proliferation of human retinal endothelial cells in vitro Anne F. Alex; Manfred Spitznas; Christian Kurts; Nicole Eter View Presentation 1947 - C0161. Circulating miRNAs as Biomarkers of Retinal Toxicity Qinghai Peng; Wenhu Huang; Walter Collette; Michelle Twamley; Shirley Aguirre; Annette John-Baptiste View Presentation 1948 - C0162. Comparison of intraocular retinal pigment epithelial (RPE) cell injections in vitrectomized wild type pigs Elliott H. Sohn; Chunhua Jiao; Robert F. Mullins; Woojin Jung; Stephen R. Russell; Edwin M. Stone; Budd A. Tucker View Presentation 1949 - C0163. Assessment of the therapeutic value of phloroglucinol in Stargardt’s disease Philippe Brabet; David Cia; Claire Vigor; Nathalie Jacquemot; Benoit Lerat; Laurent Guillou; Celine Crauste; Christian P. Hamel; Joseph L. Vercauteren View Presentation 1950 - C0164. Recurrence of macular edema after intravitreal bevacizumab injection in eyes with macular edema secondary to retinal vein occlusion young gyun Kim; Ji young Moon; Kyung Hoon Seo; Seung yong Lee; Eung Suk Kim; Seung young Yu; Hyung woo Kwak View Presentation 1951 - C0165. Increasing mitochondrial respiratory capacity is protective in models of photoreceptor cell degeneration Mausumi Bandyopadhyay; Nathan R. Perron; Cecile Nasarre; Craig Beeson; Baerbel Rohrer View Presentation 1952 - C0166. A deca-peptide inhibits retinal neovascularization by down-regulation of VEGF and up-regulation of PEDF in OIR mouse Xun Xu View Presentation 1953 - C0167. Novel GFAP Species in Retinal Gliosis John Wizeman; Paola Bargagna-Mohan; Sean O'Rourke; Royce Mohan View Presentation 1954 - C0168. Effect of Intravitreal Injection of Iodoacetic Acid in Mice as a Model of Pharmacological Induced Monolateral Photoreceptor Degeneration Sarah Roesch; Stephan Hesse; Christine Haselier; Babac A. Mazinani; Gernot Roessler; Christiane Pfarrer; Peter Walter View Presentation 1955 - C0169. PHLOROTANNIN-RICH NATURAL EXTRACT FROM BROWN SEAWEED ASCOPHYLLUM NODOSUM PREVENTS IN VITRO HIGH GLUCOSE RETINAL DAMAGES Melody Dutot; Roxane Fagon; Patrice Rat View Presentation 1956 - C0170. Fenretinide Inhibits Ocular Neovascularization (NV) by Upregulation of Bone Morphogenic Protein-2 (BMP-2) and Reduction of Inflammatory Macrophages and VEGF Rebecca K. Stevens; Peter A. Campochiaro; Ji-kui Shen; Brian C. Oveson; Sean F. Hackett; Nathan L. Mata View Presentation 1957 - C0171. Blocking the necroptosis pathway decreases RPE and photoreceptor damage induced by NaIO3 Haijiang Lin; Miin Roh; Hidetaka Matsumoto; Albert H. Alhatem; Peggy Bouzika; Yusuke Murakami; Joan W. Miller; Demetrios Vavvas View Presentation 1958 - C0172. Impact of intravitreal dexamethasone implant (Ozurdex) on macular morphology and function Maria Lucia Cascavilla; Giuseppe Querques; Rosangela Lattanzio; Lea Querques; Giacinto Triolo; Edoardo Cavallero; Francesco Bandello View Presentation 1959 - C0173. Clinical and Diagnostic Imaging Features of Anti-Retroviral Therapy (ART)-Associated Retinopathy Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 88 sur 222 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM Alcides Fernandes; John F. Payne; Sunil K. Srivastava; Steven Yeh View Presentation 1960 - C0174. S/MAR containing nanoparticles mediate long-term therapeutic gene targeting in the RPE and rescue the rpe65-/- LCA model Shannon M. Conley; Adarsha Koirala; Rasha Makkia; Zhao Liu; Mark J. Cooper; Janet R. Sparrow; Muna I. Naash View Presentation 1961 - C0175. Analysis of the binding affinity of vascular endothelial growth factor A (VEGF) to ranibizumab, aflibercept and bevacizumab Xiangdan Wang; Jihong Yang View Presentation 1962 - C0176. Low dose acetyl salicyl acid as a treatment option for central serous chorioretinopathy Nicole Stuebiger View Presentation 1963 - C0177. Ceramide Biosynthesis Inhibition Protects the Retina from Light-Induced Degeneration Md Nawajes A. Mandal; Hui Chen; Julie-Thu Tran; Michael H. Elliott; Richard S. Brush View Presentation 1964 - C0178. Ocriplasmin as an Adjunct to Vitrectomy for the Treatment of Pediatric Patients: Results of the MIC Trial Emmanuel Chang View Presentation 1965 - C0179. Quinic Acid Derivative, KZ-41 Protects Against Radiation-Induced Retinal Endothelial Cell Dysfunction: An Early – to – Late Stage Treatment of Radiation Retinopathy Jordan J. Toutounchian; Qiuhua Zhang; Jayaprakash Pagadala; Duane D. Miller; Jena J. Steinle; Charles R. Yates View Presentation 1966 - C0180. Safety of intravitreal quinupristin / dalfopristin in an animal model Veronica E. Giordano; Sergio Hernandez-Da Mota; Jose Luis Guerrero-Naranjo; Tania N. Adabache Guel; Samantha Salinas Longoria; Sonia Corredor-Casas; Guillermo Salcedo-Villanueva; Juan Manuel Jimenez-Sierra; Virgilio Morales-Canton View Presentation 1967 - C0181. Fragment crystallizable (Fc) region results in an increased systemic exposure with no significant difference in intra-ocular pharmacokinetics Jennifer Le Couter; Kapil Gadkar; J. Michael Elliott; Thomas Lee; Y. Gloria Meng; Linda Zhang; Margaret Kenrick; Saileta Prabhu; Justin M. Scheer View Presentation 1968 - C0182. EFFECT OF AN ANTIOXIDANT BLEND IN DIABETIC MACULAR EDEMA SALVATORE FARO; Teresio Avitabile; Giulia Malaguarnera; Franco Marco Livio; Maurizio G. Uva; maria vittoria cicinelli; Cristina Cassar Scalia; Elena Lionetti; Caterina Gagliano View Presentation 256. Aqueous Humor Dynamics and IOP Moderator(s): Jeffrey Kiel (Univ of Texas Hlth Sci Ctr SA) and Claudio Bucolo (University of Catania) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM Withdrawn 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM View Session Details 1969 - C0183. A Role for Myocilin in Receptor Endocytosis Brian S. McKay; Nicole R. Congrove; William M. Dismuke; W Daniel Stamer View Presentation 1970 - C0184. Differential Comparison of Aqueous Humor Phosphatidylcholines from Control and Glaucomatous Donors Ayman Aljohani; Yenifer C. Guerra; Maria C. Piqueras; Richard K. Lee; Sanjoy K. Bhattacharya View Presentation 1971 - C0185. Ocular Hypertension-Induced MMPs Production Within Optic Nerve: A Regulatory Role of δ-Opioid-Receptors Sudha Singh; Mohammad F. Pathan; Naseem Akhter; Melissa Nix; Shahid Husain View Presentation 1972 - C0186. Requirement for the proteasome, ATP and exportin-1 in the nuclear export of glucocorticoid alpha (GRα) receptor following DEX treatment in human trabecular meshwork cell-line (NTM5) Adnan Dibas; Abbot F. Clark; Thomas Yorio View Presentation 1973 - C0187. Non-invasive Intraocular Pressure Measurements in Zebrafish D Joshua Cameron; Pinakin G. Davey View Presentation 1974 - C0188. Characterization of TRPV4 expression & function in the ciliary body & trabecular meshwork Amber M. Frye; Daniel A. Ryskamp; Peter Barabas; Tunde Molnar; David Krizaj View Presentation 1975 - C0189. Ocular Hypertension-Induced Changes in the Anterior Segment of Cynomolgus Monkeys Shenouda Yacoub; Quinn Sessums; Byron H. Li; Ganesh Prasanna View Presentation 1976 - C0190. Regulation of Mammalian Sympathetic Neurotransmitter Release and Intraocular Pressure by Hydrogen Sulfide Donor, GYY 4137 Ankita Salvi; Pratik Bankhele; Jamal Jamil; Ya Fatou Njie-Mbye; Madhura S. Kulkarni; Sunny E. Ohia; Catherine A. Opere View Presentation 1977 - C0191. Episcleral Venous Pressure Elevation in Untreated Open Angle Glaucoma Arthur J. Sit; Nitika Arora; Jay W. McLaren; Mehrdad Malihi; Lilit Voskanyan View Presentation 1978 - C0192. Expansion of Schlemm’s Canal by Travoprost in Healthy Subjects determined by Fourier-Domain Optical Coherence Tomography JUNYI CHEN; Haili Huang; Shenghai Zhang; Xueli Chen; Xinghuai Sun View Presentation 1979 - C0193. Thinning of RNFL is correlated with declining of PhNR ERG amplitude in glaucomatous monkeys Byron H. Li; Nalini V. Rangaswamy; Steven Q. Sessums; Richard L. Ornberg; Ganesh Prasanna View Presentation 1980 - C0194. In Vivo Agreement of Intraocular Pressures Simultaneously Measured Using Tonometer and Manometers Placed in Anterior and Vitreous Cavity under General Anesthesia Hyun Seung Yang; June-Gone Kim View Presentation 1981 - C0195. Regulatory Roles of Anoctamin-6 in Human Trabecular Meshwork Cells Juni Banerjee; Ang Li; Chi Ting Leung; Kim Peterson-Yantorno; W Daniel Stamer; Mortimer M. Civan View Presentation 1982 - C0196. Aqueous Humor Dynamics of the Water Drinking Test in Healthy Individuals Nitika Arora; Jay W. McLaren; Arthur J. Sit View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 89 sur 222 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 1983 - C0197. Foreign-body-reaction-induced chronic ocular hypertension in rat Bing Li; Yu Wang; Shutong Cao; Olga Kraszewska; Richard Ornberg; Ganesh Prasanna View Presentation 1984 - C0198. Effect of the Water Drinking Test in Subjects with Pure Autonomic Failure and Normal Tension Glaucoma William M. Watkins; David Robertson; Karen M. Joos View Presentation 1985 - C0199. Suction-cup oculopression offers minimal-invasive opportunities of arbitrary IOP elevations in rats Theresa Lueckner; Oliver W. Gramlich; Maren Kriechbaum; Julia Teister; Norbert Pfeiffer; Franz H. Grus View Presentation 1986 - C0200. Comparative IOP lowering from single dose studies of latanoprost, timolol and ONO-9054 in Dogs and Monkeys Kazufumi Nagai; Shinsaku Yamane; Kazumi Moriyuki; Tomohiro Karakawa; Shintaro Nakao; Tsutomu Shiroya; Yutaka Shichino View Presentation 1987 - C0201. BAICALEIN LOWERS INTRAOCULAR PRESSURE IN GERBILS Chi-wai W. Do; Chi-ting T. Leung; Ho Lung Henry Chan; Mortimer M. Civan; Chi-ho To View Presentation 1988 - C0202. Definition of Normal Ophthalmic Measures in the African Green Monkey Robin J. Goody; Wenzheng Hu; Steve D. Whittaker; Steve t. Henry; Rohn Brookes; Michael J. Struharik; Erich Hechanova; Matthew S. Lawrence View Presentation 1989 - C0203. BK2A77: A novel non-peptide bradykinin B2 agonist lowers intraocular pressure in ocular hypertensive cynomolgus monkeys Ganesh Prasanna; Naj Sharif; Byron H. Li; Curtis Kelly; Shouxi Xu; Linya Li; Daniel Scott; Rad Daly; Mark Hellberg; Keith Combrink View Presentation 1990 - C0204. Evaluation of Changes in Intraocular Pressure Immediately After Intravitreal Injection of Anti-VEGF Medication Julio C. Chora; Victor H. Gonzalez View Presentation 1991 - C0205. Efficacy and safety of Polyquad-preserved Travoprost in Ocular Hypertensives and Open Angle Glaucoma patients: an open label, observational, 6month, switch study Teresa Rolle; Rachele Penna; Alessandro G. Actis; Luigia Scudeller; Gianmaria Pasinetti; Gemma C. Rossi View Presentation 1992 - C0206. Ocular Hypotensive Activity Of A New Melatonin Analog OPD-11, In Normotensive Rabbits Maria Caballo Gonzalez; Carmen del Campo; Loreto Salazar; Vanessa AndresGuerrero; Marta Vicario de la Torre; Rocio Herrero-Vanrell; Irene T. Molina-Martínez View Presentation 1993 - C0207. Comparison of Rebound Tonometry in Sedated and Non-Sedated Non Human Primates (NHP) Mark Vezina; Sylvie Wise; Kelly Tenneson; Martin Bussieres; Timothy Bryant; Elridge Edwards View Presentation 1994 - C0208. Expression of Circadian Rhythm Genes in the Mouse Iris-Ciliary Body Complex Jeffrey J. Dunmire; Lauren Dalvin; Rachida Bouhenni; Deepak P. Edward View Presentation 1995 - C0209. Sphingosine-1-Phosphate signaling in cultured human trabecular meshwork cells Sietse T. Braakman; Kristin M. Perkumas; Darryl R. Overby; David F. Woodward; W Daniel Stamer View Presentation 1996 - C0210. Shear Stress Stimulation of NO release from Schlemm’s Canal Cells Nicole E. Ashpole; Darryl R. Overby; C R. Ethier; W Daniel Stamer View Presentation 1997 - C0211. Peptide and Non-Peptide Bradykinin (BK) Agonists and Antagonists Help Define Functional BK Receptors in Human Trabecular Meshwork and Ciliary Body Naj Sharif; Parvaneh Katoli; Curtis R. Kelly; Linya Li; Shouxi Xu; Yu Wang; Ganesh Prasanna; Keith D. Combrink; Mark Hellberg; Shahid Husain View Presentation 1998 - C0212. Effect of ONO-9054 on Aqueous Humor Dynamics in Monkeys Tomohiro Karakawa; Shinsaku Yamane; Kazufumi Nagai; Shintaro Nakao; Tsutomu Shiroya; Yutaka Shichino View Presentation 1999 - C0213. Cabergoline and IOP: implications for structure-based drug discovery of selective dopaminergic ligands Filippo Drago; Chiara Bianca Maria Platania; Giuseppina Marrazzo; Gian Marco Leggio; Claudio Bucolo View Presentation 2000 - C0214. Twenty-four hour Variations in Ocular Biometric Parameters in Patients with Ocular Hypertension Shan Fan; Vikas Gulati; Donna G. Neely; Nathan V. Harms; Carol B. Toris View Presentation 2001 - C0215. Voltage-coupled single-needle constant-pressure anterior chamber perfusion in live mice MinHee K. Ko; Aleksandr Yelenskiy; Jose M. Gonzalez; James C. Tan View Presentation 2002 - C0216. Effects of Nitric Oxide Donor on Outflow Facility in Mice Jason Y. Chang; Catherine M. Marando; C R. Ethier; W Daniel Stamer; Darryl R. Overby View Presentation 2003 - C0217. Tracking protein endocytosis and trafficking to exosomes released from trabecular meshwork cells W M. Dismuke; Brian S. McKay; Aaditya Khatri; Kristin M. Perkumas; W Daniel Stamer View Presentation 2004 - C0218. PEDF Effects on Outflow Facility Morgan E. Rogers; Iris Navarro; Kristin M. Perkumas; R Rand Allingham; Pratap Challa; Craig E. Crosson; W Daniel Stamer View Presentation 2005 - C0219. Ocular hypertensive effect of pilocarpine in the anesthetized rat Jeffrey W. Kiel; Alma L. Maldonado View Presentation 2006 - C0220. Poly-Unsaturated Fatty Acids in Human Aqueous Humor Jonathan D. Nussdorf; Janet Manalac; Yan Lu; Song Hong; Nicolas G. Bazan View Presentation 257. Retina/RPE: Molecular and Cell Biology Moderator(s): Gianluca Tosini (Morehouse School of Medicine) and Monte Del Monte (Univ of Michigan-Kellogg Eye Ctr) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM View Session Details 2007 - D0038. CHARACTERIZATION OF CHICKEN RETINAL HORIZONTAL CELL PRIMARY CULTURES Mario E. Guido; Luis P. Morera; Nicolás Díaz View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 90 sur 222 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 2008 - D0039. Effect of prostaglandin E2 on collagen gel contraction in mouse retinal pigment epithelium cells Tomoko Orita; Kazuhiro Kimura; Koh-hei Sonoda View Presentation 2009 - D0040. Age-dependent Biochemical Changes in the Retina of Glutaredoxin 2 (Grx2) Knockout Mice Hongli Wu; Marjorie F. Lou View Presentation 2010 - D0041. Role of Hypoxia-inducible Factor 1 Alpha in Hydrogen Peroxide-induced Human Retinal Pigment Epithelial Cell Death Piyush C. Kothary; Patrick Lee; Neil B. Parikh; Sara Abraham; Monte A. Del Monte View Presentation 2011 - D0042. Extremely brief light-preconditioning in pigmented mouse model of lightinduced retinal degeneration (LIRD) Priscila P. Cunha; Micah A. Chrenek; Jana T. Sellers; Jeffrey H. Boatright View Presentation 2012 - D0043. TGF-beta2 promotes RPE cell invasion into collagen gel by mediating urokinase-type plasminogen activator (uPA) expression Koji Sugioka; Aya Kodama; Koji Yoshida; Kiyotaka Okada; Shunji Kusaka; Chota Matsumoto; Yoshikazu Shimomura View Presentation 2013 - D0044. Light induced retinal damage in 129sv pigmented mice Micah A. Chrenek; Jana T. Sellers; Stephanie L. Foster; Dustin R. Zuelke; Tiffany L. Liao; John M. Nickerson; Jeffrey H. Boatright View Presentation 2014 - D0045. Analysis of Human Retinal Pigment Epithelium (RPE) Morphometry in the Macula of the Normal Aging Eye Shagun K. Arora; Alia Rashid; Micah A. Chrenek; Qing Zhang; Soojung Park; Hans E. Grossniklaus; John M. Nickerson View Presentation 2015 - D0046. Spatial Analysis of Morphometry of Retinal Pigment Epithelium in the Normal Human Eye Alia Rashid; Shagun K. Arora; Micah A. Chrenek; Soojung Park; Qing Zhang; John M. Nickerson; Hans E. Grossniklaus View Presentation 2016 - D0047. AMP-activated Protein Kinase Suppresses Matrix Metalloproteinase-9 Expression and Cell Migration of Mouse Retinal Pigment Epithelium Yuki Morizane; Kimio Takeuchi; Jun Suzuki; Takeru Yoshimura; Yusuke Murakami; Maki Kayama; Fumiaki Kumase; Benoit Viollet; Joan W. Miller; Demetrios Vavvas View Presentation 2017 - D0048. Identification of genes critical for normal pigmentation of RPE and crossing of the optic nerves in mouse embryos Sonia Guha; Alejandra Young; Debora B. Farber View Presentation 2018 - D0049. Rosemary extract and its effects on retinal gene expression with and without photic challenge Alison Ziesel; Daniel T. Organisciak; Ruth Darrow; Christine Rapp; John C. Lang; Paul Wong View Presentation 2019 - D0050. Dopamine Entrains The Circadaian Rhythm of PER2::LUC Bioluminescence in The Mouse Retinal Pigment Epithelium Kenkichi Baba; Susana Contreras-Alcantara; Gianluca Tosini View Presentation 2020 - D0051. The transcription factor neural retina leucine zipper controls photoreceptor-specific expression of Reep6 Hong Hao; Shobi Veleri; Bo Sun; Raman Sood; Paul Liu; Anand Swaroop View Presentation 2021 - D0052. Elucidating the mechanism behind enhanced retinal transduction of an AAV2 variant Kenton T. Woodard; Richard Samulski View Presentation 2022 - D0053. Characterization of Age Related Maculopathy Susceptibility 2 (ARMS2) transcripts in human and Cynomolgus macaque retina Peng Yu; Darius Donohue; Kristina L. Rhoades; Carl Romano; Rajkumar V. Patil View Presentation 2023 - D0054. Generation of GARP2-Specific Knockout Mice Using Zinc Finger Nuclease Technology Steven J. Pittler; Delores Davis; Larry W. Johnson; Robert A. Kesterson View Presentation 258. Immune Responses and Immunopathology Moderator(s): Johannes Schwartzkopff (University of Freiburg) and Sharmila Masli (Boston University School of Medicine) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM View Session Details 2024 - D0163. IL-2/IL-2 Ab complex plus rapamycin ameliorate experimental autoimmune uveoretinitis associated with expansion of CD4+Foxp3+ regulatory T cells Hiroshi Keino; Yasuhiko Sato; Annabelle A. Okada View Presentation 2025 - D0164. T-cell and cytokine investigations in an experimental model of retinal ganglion cell loss Sandra Kuehn; Rozina Noristani; Mathias Kuehn; Burkhard H. Dick; Stephanie C. Joachim View Presentation 2026 - D0165. Altered CD8+ T cell function in human non-infectious uveitis Sima Hirani; Ping Chen; Shayma Jawad; Ian A. Thompson; Baoying Liu; Lai Wei; H Nida Sen; Richard W. Lee; Robert B. Nussenblatt View Presentation 2027 - D0166. The contribution of T cells to retinopathy of prematurity in mice Dean Talia; Tong Zhu; Alex Agrotis; Robyn M. Slattery; Melanie Le Page; Fabienne Mackay-Fisson; Jennifer L. Wilkinson-Berka View Presentation 2028 - D0167. Fas-dependent release of high-mobility group protein B1 (HMGB1) in the eye is critical for the development of experimental autoimmune uveitis (EAU) initiated by uveitogenic T cells Guomin Jiang; Amir R. Hajrasouliha; Henry J. Kaplan; Hui Shao View Presentation 2029 - D0168. Regulatory T cell levels and cytokine production in active non-infectious uveitis: in vitro effect of anti-TNF-α, dexamethasone, and cyclosporine Blanca Molins; Victor Llorens; Marina Mesquida; Laura Pelegrin; Alfredo Adan Civera View Presentation 2030 - D0169. Local Regulatory T Cells of the Retina Protect Against Spontaneous and Induced Autoimmune Disease Scott W. McPherson; Neal D. Heuss; Mark J. Pierson; Dale S. Gregerson View Presentation 2031 - D0170. Investigating the response of naive T-cells to the three isoforms of TGFβ Robert J. Barry; David Withers; Philip I. Murray; Peter J. Lane; John Curnow View Presentation 2032 - D0171. V-domain Ig Suppressor of T Cell Activation (VISTA) is Necessary for Corneal Allograft Survival Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 91 sur 222 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM Tomoyuki Kunishige; Hiroko Taniguchi; Tatsukuni Ohno; Miyuki Azuma; Junko Hori View Presentation 2033 - D0172. Leukocyte Infiltrate in Rabbit Tears Post Intravenous Muramyl Dipeptide Marlyn P. Langford; Tyler W. Plauche; Claude Y. Bundrick; Thomas B. Redens View Presentation 2034 - D0173. Dendritic cells from uveitis patients have a mature phenotype and a reduced capacity to take up antigen Ping Chen; Baoying Liu; Richard W. Lee; H Nida Sen; Zhiyu Li; Shayma Jawad; Sima Hirani; Lai Wei; Robert B. Nussenblatt View Presentation 2035 - D0174. Identifying and classifying nonspecific orbital inflammation (NSOI) by gene expression array James T. Rosenbaum; Dongseok Choi; Christina A. Harrington; Gerald J. Harris; Craig N. Czyz; Valerie A. White; Eric A. Steele; Bobby S. Korn; David J. Wilson; Stephen R. Planck View Presentation 2036 - D0175. Association of Thrombospondin-1 Polymorphism with Predisposition to Chronic Dry Eye Laura Contreras-Ruiz; Bruce Turpie; Denise S. Ryan; Rose K. Sia; Kraig S. Bower; Darlene A. Dartt; Sharmila Masli View Presentation 2037 - D0176. Expression and Function of the NLRC4/NAIP5 Inflammasome in the Ocular Surface: Ramifications of Eicosanoid Storms Karsten Gronert; Kyle M. Hu; David W. Lin; Yuning Wang; Samantha B. Wang View Presentation 2038 - D0177. What Is the Lineage of IL-17+IFN-γ+CD4+ T Cells in Dry Eye Disease? Yihe Chen; Sunil K. Chauhan; Zahra Sadrai; Jing Hua; Reza Dana View Presentation 2039 - D0178. Mechanisms involved in conjunctival immunological tolerance breakdown by eye drop preservatives Jeremías G. Galletti; Laura Gabelloni; Florencia Sabbione; Pablo Chiaradia; Mirta N. Giordano; Javier F. Casiraghi View Presentation 2040 - D0179. Gene expression in thyroid eye disease relative to other orbital diseases Stephen R. Planck; Dongseok Choi; Christina A. Harrington; Craig N. Czyz; Roger A. Dailey; Peter J. Dolman; Gerald J. Harris; Patrick Stauffer; David J. Wilson; James T. Rosenbaum View Presentation 2041 - D0180. An optical coherence tomography based in vivo scoring system for experimental autoimmune uveoretinitis Colin J. Chu; Philipp Herrmann; Livia S. Carvalho; Sidath E. Liyanage; James W. Bainbridge; Robin R. Ali; Andrew D. Dick; Ulrich F. Luhmann View Presentation 2042 - D0181. Age related aqueous cytokine and growth factor changes in cataract patients Jing Li; Yan Zheng; Yu Xu; Shin-Jye Lee; Yuqing Rao; Qi Zhang; Peiquan Zhao View Presentation 2043 - D0182. The Herpes Simplex Virus-1 Latency-Associated Transcript Promotes Functional Exhaustion of Virus-Specific CD8+ T Cells in Trigeminal Ganglia of Latently Infected “humanized” HLA-transgenic rabbits Lbachir BenMohamed; Xavier Dervillez; Huma Qureshi; Aziz A. Chentoufi; Chelsea Nguyen; Oscar R. Diaz; Anthony B. Nesburn; Steven L. Wechsler View Presentation 2044 - D0183. Two Human Leukocyte Antigen (HLA)-A*0201-Restricted Epitopes Identified from Herpes Simplex Virus Glycoprotein B are Recognized Exclusively by CD8+ T cells from Asymptomatic Individuals and Protect Against Ocular Herpes Anthony B. Nesburn; Xavier Dervillez; Huma Qureshi; Aziz A. Chentoufi; Oscar R. Diaz; John Sidney; Alessandro Sette; Maria C. Villacres; Steven L. Wechsler; Lbachir BenMohamed View Presentation 2045 - D0184. The Role of Endogenous TLR4 Ligand S100A8/A9 in Ocular Inflammation Christina Metea; Joe Ensign-Lewis; Alec Amram; Holly L. Rosenzweig; Thomas Vogl; Johannes Roth; Stephen R. Planck; James T. Rosenbaum View Presentation 2046 - D0185. Chemokine C-C motif ligand 7 as a Costimulatory Signal on Mast Cell Activation and Motility Chuan-Hui Kuo; Andrea Collins; Masaharu Ohbayashi; Santa Ono View Presentation 2047 - D0186. Immunomodulatory therapy and multiple sclerosis-associated uveitis Gueorgui T. Markov; Kittikamol Vongpaisarnsin; C. Stephen Foster View Presentation 2048 - D0187. CD163+ and CD68+ cells in the adult human eye SVETLANA CHEREPANOFF; Enisa Hasic; Paul G. McMenamin; Mark C. Gillies View Presentation 2049 - D0188. Cytokine Production in the Endotoxin-Induced Uveitis Model Abrar A. Rageh; Michael Jordan; Neal D. Heuss; Dale S. Gregerson; Deborah A. Ferrington; Sandra R. Montezuma View Presentation 2050 - D0189. Osteopontin is Expressed by Microglia and T Cells and Regulated by STAT3 Chengrong Yu; Waynekid Kam; Ivy M. Dambuza; Bernadette Marrero; Rashid M. Mahdi; Charles E. Egwuagu View Presentation 2051 - D0190. Cataract and uveitis: Comparison of two different anti inflammatory regimens for the prevention of post-operative complications Nathalie Butel; Emmanuelle Champion; Valerie Touitou; Christine Fardeau; Bahram Bodaghi; Phuc Le Hoang View Presentation 2052 - D0191. Response of uveitis-related retinal vasculitis to therapy with systemic infliximab Pramod K. Sharma; Gueorgui T. Markov; C. Stephen Foster View Presentation 259. Corneal Immunology, Allergy, Neovascularization View Session Details Moderator(s): Pedram Hamrah (Harvard Medical School/SERI/MEEI) and Scott Robbie (UCL Institute of Ophthalmology) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 2053 - D0192. CICATRICIAL CHANGES IN OCULAR PEMPHIGUS Patricia Chirinos-Saldaña; Isaac Zuñiga-Gonzalez; Julio C. Hernandez-Camarena; Alejandro Navas; Tito Ramirez-Luquín; Atzin Robles-Contreras; Maria C. JimenezMartinez; Arturo J. Ramirez-Miranda; Enrique O. Graue-Hernández View Presentation 2054 - D0193. The Effect of Trigeminal Neurons on the Expression of Maturation Markers by Bone Marrow-Derived Dendritic Cells Sang-Mok Lee; William Stevenson; Kishore Reddy Katikireddy; Hyun Soo Lee; Thomas H. Dohlman; Sunil K. Chauhan; Jing Hua; Zahra Sadrai; Masahiro Omoto; Reza Dana View Presentation 2055 - D0194. Effect of Interleukin-17(IL-17) and IL-17 receptor on ocular surface inflammation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 92 sur 222 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM Ai Yamada; Tohru Sakimoto; Akiko Ishimori; Takako Ohnishi; Satoshi Sugaya; Mitsuru Sawa View Presentation 2056 - D0195. Host Mesenchymal Stem Cells Home to Transplanted Cornea and Promote Allograft Survival Masahiro Omoto; Yiping Jin; Sunil K. Chauhan View Presentation 2057 - D0196. The Cross-reactivity of Subsequent Corneal Allografting After Xenocorneal Transplantation Using Decellularized Porcine Lamella Against Allo-antigens in Primates Hyuk Jin Choi; Jong Joo Lee; Mee Kum Kim; Won Ryang Wee; Hyun Ju Lee; Ah Young Ko; Jae-Il Lee; Hee Jung Kang View Presentation 2058 - D0197. Tear expression profiling of cytokine, chemokine and soluble receptor in keratoconus patients Jeewon Mok; Choun-Ki Joo View Presentation 2059 - D0198. HC-HA Suppresses Inflammatory and Immune Responses and Improves Murine Corneal Allograft Survival Hua He; Yaohong Tan; Victor L. Perez; Scheffer C. Tseng View Presentation 2060 - D0199. Polarization of Anti-inflammatory M2 Macrophages by HC-HA Complex Purified from Amniotic Membrane or Reconstituted In Vitro Sean Tighe; Hua He; Suzhen Zhang; Scheffer C. Tseng View Presentation 2061 - D0200. In Vivo Administration of Interleukin-2 Increases Corneal Allograft Survival through Expansion of CD4+CD25+ T Regulatory Cells Maryam Tahvildari; Parisa Emami-Naeini; Yihe Chen; Masahiro Omoto; Jing Hua; Sunil K. Chauhan; Reza Dana View Presentation 2062 - D0201. Proteomic Analysis of Plasma and Mucosal Samples from Patients with Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Julia Malalis; Christine Mata; Daniel Kahn; Amy Lin; Michael J. Mosier; Charles S. Bouchard; Josephine Cunanan; Omer Iqbal; Debra Hoppensteadt; Jawed Fareed View Presentation 2063 - D0202. Morphologic Dendritic Immune Cells Parameters Reveal Differential Characteristics between the Central and Peripheral Cornea: an In Vivo Confocal Microscopy Normative Data Clara M. Colon; Bernardo M. Cavalcanti; Shruti Aggarwal; Andrea Cruzat; Candice Williams; Douglas Critser; Amy Watts; Christine W. Sindt; Pedram Hamrah View Presentation 2064 - D0203. Antimicrobial peptides protect the corneas from bacteria and fungi infection Chen Dong; Chen Dong; Nan Gao; Gi Sang Yoon; Fushin X. Yu View Presentation 2065 - D0204. Effect of hydroxychloroquine on the inflammation in antigen presenting cells interacted with damaged corneal epithelial cells Chang Ho Yoon; Jin Suk Ryu; Mee Kum Kim; Won Ryang Wee View Presentation 2066 - D0205. Reduced expression of IL17 following rejection in baby rat keratoplasty Antonia Hildebrand; Thomas Reinhard; Johannes Schwartzkopff View Presentation 2067 - D0206. Vitamin D3 attenuates Toll-like receptor 3 induced inflammation in human corneal epithelial cells Rose Y. Reins; Alison M. McDermott View Presentation 2068 - D0207. HC-HA Complex Purified from Amniotic Membrane Exerts Anti-scarring Effect by Suppressing TGFβ1 but Activating TGFβ3 Signaling in Human Corneal Fibroblasts Fu Li; Ying-Ting Zhu; Hua He; Su-Zhen Zhang; Scheffer C. Tseng View Presentation 2069 - D0208. The response of tear film neutrophils to occasional overnight lens wear Maud Gorbet; Doerte Luensmann; Lyndon W. Jones View Presentation 2070 - D0209. TLR3, RIG-1 and MDA5 are constitutively expressed on human corneal limbal fibroblasts and induce proinflammatory response Alfredo Domínguez; Rodrigo Bolanos; Jeanet Serafín; Jessica Nieves-Hernández; Yonathan Garfias View Presentation 2071 - D0210. Bilateral Up-regulation of Limbal Intravascular Adhesion Molecules Mediates Cell Infiltration into the Cornea after Unilateral Trigeminal Nerve Axotomy Deshea L. Harris; Takefumi Yamaguchi; Aslihan Turhan; Ulrich von Andrian; Pedram Hamrah View Presentation 2072 - D0211. Tear Molecule Levels and Conjunctival Inflammatory Gene Expression in Atopic Keratoconjunctivitis (AKC) Amalia Enriquez-De-Salamanca; Erma Trias; Verónica Martinez-Tottil; Lidia Cocho; Carmen García-Vázquez; Maria J. Gonzalez-Garcia; Margarita Calonge View Presentation 2073 - D0212. Measurement of wheat-specific tear IgE in patients with allergic conjunctivitis Tatsuya Mimura View Presentation 2074 - D0213. In vitro toxicity of omalizumab in conjuctival epithelial cells Anne-Sophie Benischke; Albert Neutzner; Christoph Tappeiner; David Goldblum View Presentation 2075 - D0214. Effects of IL-13 Stimulation on Primary Mouse Conjunctival Epithelial Cultures Johanna Tukler Henriksson; Xiaobo Zhang; De-Quan Li; Cintia S. De Paiva; Stephen C. Pflugfelder View Presentation 2076 - D0215. Increased proliferation of cultured conjunctival epithelium in IFN-γ deficient strains Meng Chen; Terry G. Coursey; Johanna Tukler Henriksson; Cintia S. De Paiva; DeQuan Li; Stephen C. Pflugfelder View Presentation 2077 - D0216. Detection of natural helper cells in innate immune system-dependent mouse conjunctivitis model Yosuke Asada; Akira Matsuda; Kanji Hori; Satoshi Iwamoto; Nobuyuki Ebihara; Susumu Nakae; Akira Murakami View Presentation 2078 - D0217. The Synergistic Effects between Bevacizumab and Cyclosporin A (Cys A) reduced the MMP-3 and MMP-13 Expression and the Migration on Cultured Pterygial Fibroblast Cells and Tissues Yeoun-Hee Kim; Young Jeung Park; Sun-Hee Kang; Jae-Chang Jung; Kyoo Won Lee View Presentation 2079 - D0218. Topical Cyclosporine A for the Management of Chronic Follicular Conjunctivitis Natasha V. Nayak; Anton M. Kolomeyer; Jason S. Kim; Eliott S. Kim; Christina Fang; David S. Chu Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 93 sur 222 View Presentation 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 2080 - D0219. Suppression of TLR3-Inducible Gene Expression by EP3 in Conjunctival Epithelium Mayumi Ueta; Shuh Narumiya; Shigeru Kinoshita View Presentation 2081 - D0220. Model of allergic keratoconjunctivitis - Stat6 signaling in chronic inflammation Michael Conwell; Sonia DaSilva-Arnold; Na Luo; Wei Li; Jeffery Travers; Yang Sun View Presentation 2082 - D0221. Molecular mechanism of corneal neovascularization inhibition by decorin therapy Ashish Tandon; Ajay Sharma; Jason T. Rodier; Rajiv R. Mohan View Presentation 2083 - D0222. Recurrent corneal inflammation stimulates lymphatic vessel memory Richard M. Tempero; Alicia L. Conner; Philip M. Kelley View Presentation 2084 - D0223. The Effects and Underlying Mechanism of Bevacizumab (Avastin) in Inhibiting Corneal Neovascularization in a Rabbit Closed Eye Contact Lens Wear Model Wei-Li Chen; Yan-Ming Chen ; Fung-Rong Hu View Presentation 2085 - D0224. SAMHD1 is a Novel Regulator of Soluble Flt-1 leah owen; Derick G. Holt; Hironori Uehara; Balamurali K. Ambati View Presentation 2086 - D0225. Serum eye drops promote vascular endothelial cell proliferation in vitro and antagonize (antiangiogenic) VEGF blockade in vivo Deniz Hos; Konrad R. Koch; Felix Bock; Claus Cursiefen; Ludwig M. Heindl View Presentation 2087 - D0226. Sterculic Acid Antagonizes 7-ketocholesterol-mediated Corneal Angiogenesis Joshua Chou; Juan Amaral; Jung W. Lee; Ignacio R. Rodriguez View Presentation 2088 - D0227. Role of IL-7 in Corneal Lymphangiogenesis Tatiana Ecoiffier; Maria Iolyeva; Cornelia Halin; Lu Chen View Presentation 2089 - D0228. Suppression of Corneal Angiogenesis by Toll-like Receptors Lei Liu; Jiahui Wu; Andrew D. Dick View Presentation 2090 - D0229. Subconjunctival Cyclosporine A implants do not affect corneal neovascularisation after transplantation: results of a randomized clinical trial Claus Cursiefen; Thomas Reinhard; Felix Bock; Hans-Ulrich Prokosch View Presentation 2091 - D0230. Role of Non-Endothelial Cells in Corneal Angiogenesis Jin Zhao; Takayuki Nagasaki View Presentation 2092 - D0231. Impaired angiogenic response in cornea by lacking TRPV1 in mice Katsuo Tomoyose; Yuka Okada; Takayoshi Sumioka; Kumi Shirai; Shizuya Saika View Presentation 2093 - D0232. Photodynamic Ablation of Lymphatic Vessels in the Cornea Franziska Bucher; Yanlong Bi; Claus Cursiefen; Felix Bock View Presentation 2094 - D0233. Formation and Regulation of Lymphatic Valves during Inflammation Tan N. Truong; Eda I. Altiok; Eric Huang; Tatiana Ecoiffier; Don Yuen; Toshimitsu Uede; Lu Chen View Presentation 2095 - D0234. MicroRNA-184 Regulates Corneal Lymphangiogenesis Lu Chen; Sammy Grimaldo; Tatiana Ecoiffier; Don Yuen View Presentation 2096 - D0235. Live Imaging of Lymphatic Valve Formation after Corneal Transplantation Gyeong Jin Kang; Tatiana Ecoiffier; Young-Kwon Hong; Lu Chen View Presentation 2097 - D0236. Novel Characterization of MHC-Class II Positive Cells in Embryonic Cornea during Spontaneous Lymphatic Events Don Yuen; Guangyu Li; Lu Chen View Presentation 2098 - D0237. Deletion of Foxc1 and/or Foxc2 from neural crest cells leads to corneal vascularization and anterior segment dysgenesis Tsutomu Kume; Kathryn M. Schultz; Amy Sasman; Seungwoon Seo View Presentation 2099 - D0238. Topical Infliximab as an inhibitor of corneal hemangiogenesis and lymphangiogenesis Giulio Ferrari; Fabio Bignami; Chiara Giacomini; Paolo Rama View Presentation 2100 - D0239. Effect of LYVE-1 on FGF2-induced lymphangiogenesis in vivo Birgit Regenfuss; Natalia Platonova; Géraldine Miquel; Said Taouji; Eric Chevet; Andreas Bikfalvi; Claus Cursiefen View Presentation 2101 - D0240. Analysis of VEGFR-1 Isoforms in Pax6-deficient Mice Corneas Phillip A. Moore; Peter J. Accola; Barbara Artelt; Megan Aarnio; James D. Lauderdale View Presentation 2102 - D0241. Use of Amaranthus leucocarpus lectin to determine corneal neovascularization Valeria L. Coria; Gibran A. Estua; Alfredo Domínguez; Edgar Zenteno; Jessica NievesHernández; Yonathan Garfias View Presentation 2103 - D0242. Netrin-4 mediates corneal neovascularization Anna-Karina Maier; Sabrina V. Klein; Norbert Kociok; Aline Riechardt; Enken Gundlach; Claudia Steger; Olaf Strauss; Antonia M. Joussen View Presentation 2104 - D0243. Subconjunctival and intrastromal Bevacizumab to control of corneal neovascularization and opacification Silvia Mendez; Maria Santiago; Elena Raposo; Rosario Touriño; Maria Teresa Rodriguez-Ares View Presentation 2105 - D0244. Corneal Organ Culture Angiogenesis Model Sally S. Twining; Hanzhu Zhang; Debra J. Warejcka View Presentation 2106 - D0245. UV-Crosslinking for Fixation of Biosynthetic Corneal Collagen Implants Kerstin M. Wand; Karin Kobuch; Michael Baumann; May Griffith; Mohammad M. Islam; Johannes Junger; Raphael T. Neuhann; Chris Lohmann View Presentation 260. Conjunctiva Cell Biology Moderator(s): Shyam Chaurasia (Singapore Eye Research Inst) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM View Session Details 2107 - D0334. Development of a conjunctival tissue substitute on the basis of plastic compressed collagen Cornelia Corinne Drechsler; Alvena Kureshi; Stephan Reichl; Gerd Geerling; Julie T. Daniels; Stefan Schrader Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 94 sur 222 View Presentation 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 2108 - D0335. Lymphatic Microvessel Density as a Predictive Marker for the Recurrence Time of Pterygium: A 3-year Follow-up Study Haotian Lin; Lixia Luo; Shiqi Ling; Wan Chen; Zhaochuan Liu; Xiaojian Zhong; Changrui Wu; Weirong Chen; Yizhi Liu View Presentation 2109 - D0336. NHE8 Participates in Electrolyte and Water Secretion in Conjunctival and Lacrimal Gland Epithelia Mingwu Wang; Jing Li; Fayez K. Ghishan; Hua Xu View Presentation 2110 - D0337. Carboxypeptidase A3 expression in intraepithelial mast cells of chronic allergic conjunctivitis Kanji Hori; Nobuyuki Ebihara; Toshinari Funaki; Kaori Ohtomo; Yosuke Asada; Akira Murakami; Akira Matsuda View Presentation 2111 - D0338. TNFα is required for normal tissue repair in injured mouse conjunctiva Osamu Yamanaka; Ai Kitano; Yuka Okada; Winston W. Kao; Shizuya Saika View Presentation 2112 - D0339. Substance P is a candidate for conjunctival epithelial cell derived factors inducing CCL2 expression in mast cells Satoshi Iwamoto; Satoshi Kawasaki; Yosuke Asada; Kanji Hori; Akira Murakami; Nobuyuki Ebihara; Akira Matsuda View Presentation 2113 - D0340. Giant Conjunctival Nevus: Clinical Features and Natural Course in 32 Cases Phoebe Mellen; Audrey C. Regillo; Swathi Kaliki; Sara Lally; Carol L. Shields; Jerry Shields View Presentation 2114 - D0341. Resolvin D1 Receptor Activation Counter-regulates H1 histamine receptors in human and rat conjunctival goblet cells Robin R. Hodges; Dayu Li; Richard B. Carozza; Marie A. Shatos; Nan Chiang; Charles N. Serhan; Darlene A. Dartt View Presentation 2115 - D0342. Efficacy of rituximab in severe ocular cicatricial pemphigoid Serge Doan; Sophie Stephan; Catherine Prost; Marina Alexandre; Isabelle Cochereau; Eric E. Gabison View Presentation 2116 - D0343. Survival with Squamous Cell Carcinoma of the Conjunctiva in the United States 1973-2009 Aaron Hendrix; Mark Hendrix View Presentation 2117 - D0344. Effect of Cyclosporin A (Cys A) to the Matrix Metalloproteinase (MMP)-3 and MMP-13 on the Migration of Cultured Pterygial Fibroblast Cells Young Jeung Park; Yeoun-Hee Kim; Se-Hyung Lee; Jae-Chang Jung; Kyoo Won Lee View Presentation 2118 - D0345. Histologic characteristics of conjunctivochalasis and its correlation with lymphangiectasis Woo C. Park; Jeong Bum Bae; Won Yeol Ryu View Presentation 2119 - D0346. Cysteinyl leukotriene receptors expression in the giant papillae of the chronic allergic conjunctivitis Kaori Ohtomo; Nobuyuki Ebihara; Norihiko Yokoi; Satoshi Kawasaki; Akira Murakami; Akira Matsuda View Presentation 2120 - D0347. Constitutive Expression of PTX3 in HC-HA Complex by Human Amniotic Membrane Cells Su-Zhen Zhang; Hua He; Ying-Ting Zhu; Scheffer C. Tseng View Presentation 2121 - D0348. Lymphatic and Blood Vessel Density in Human Conjunctiva Following Glaucoma Surgery Mirela Krasniqi; Heidi Rassavong; Rachida Bouhenni; Jeffrey J. Dunmire; Sami a. Al Shahwan; Ibrahim Al Jadaan; Hind Alkatan; Deepak P. Edward View Presentation 2122 - D0349. Molecular Mechanisms of Inflammatory Apoptosis of Conjunctival Epithelial Cells and T cells: Effect of Cyclosporin A (CsA) Jianping Gao; Reuben Sana; Virginia L. Calder; Margarita Calonge; Wanju Lee; Larry A. Wheeler; Michael E. Stern View Presentation 2123 - D0350. Immunohistochemical alterations in cicatricial conjunctivitis associated with Behcet’s disease Kazunari Higa; Yoshiyuki Satake; Daisuke Tomida; Katsuya Yamazoe; Takahiko Hayashi; Naoki Toriyama; Jun Shimazaki View Presentation 2124 - D0351. Characterization of the Gene Expression Profile of Conjunctivochalasis Stella C. Paparizos; Rachida Bouhenni; Jeffrey J. Dunmire; Todd L. Beyer; Khaled K. Abu-Amero; Deepak P. Edward View Presentation 2125 - D0352. Topical Cyclosporine A for the Treatment of Chronic Keratoconjunctivitis Jason S. Kim; Anton M. Kolomeyer; Christina Fang; Natasha V. Nayak; Eliott Kim; David S. Chu View Presentation 2126 - D0353. Squamous Metaplasia May Persist after Pterygium Excision and LimbalConjunctival Autograft Soo Jeong Ryu; Sang Beom Han; Hee Kyung Yang; Won Ryang Wee; Joon Young Hyon View Presentation 2127 - D0354. Effect of Nerve Growth Factor on in vitro Human Primary Conjuntival Epithelial Cell Apoptosis Induced by Hyperosmolar Stress Hungwon Tchah; Soon-Suk Kang; Eun-Soon Kim; Jae-yong Kim View Presentation 2128 - D0355. Use of Evicel as a Fibrin Adhesive in Pterygium Surgery Lena Dixit; Todd R. Shepler View Presentation 2129 - D0356. HLA-DR expression/mobilization on the conjunctival epithelial cells exposed to hyperosmolarity and desiccative stress Christophe Roubeix; Luisa Riancho; Christophe Baudouin; Francoise Brignole-Baudouin View Presentation 2130 - D0357. Conjunctival Melanoacanthoma: A New Pigmented Conjunctival Entity Saeed F. Al Wadani; Michael J. Mines; L. David Monroe; Charles Eberhart View Presentation 261. Low Vision Group: Opportunities and Challenges for Clinical Trials of Treatment or Rehabilitation Strategies for Vision Enhancement Moderator(s): Robert Massof (Johns Hopkins Wilmer Eye Inst) and Gary Rubin (UCL Institute of Ophthalmology) 1:00 PM - 2:30 PM; TCC LL 4/5 1:00 PM - 1:18 PM View Session Details RCTs in Low Vision Rehabilitation: Lessons Learned from Trials in the UK Hospital Eye Service Robert Harper Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 95 sur 222 View Presentation 1:18 PM - 1:36 PM 1:36 PM - 1:54 PM 1:54 PM - 2:12 PM 2:12 PM - 2:30 PM Difficulties in Designing Clinical Trials: Recruitment and Retention Joan Stelmack View Presentation Outcome Measures: What Constitutes Success? Hannah M. Dunbar View Presentation Opportunities and Challenges: Mobility-related Outcome Measures Alexandra R. Bowers View Presentation Challenges of Matching Effective Endpoints to Treatment and Participant Ability Ronald A. Schuchard View Presentation 262. From Stolen Ideas to False Data: Shining a Light on Scientific Misconduct Moderator(s): M Elizabeth Hartnett (Moran Eye Center, Univ of Utah) and Cynthia Owsley (Univ of Alabama at Birmingham) 1:00 PM - 2:30 PM; 606/607 1:00 PM - 1:25 PM 1:25 PM - 1:50 PM 1:50 PM - 2:15 PM 2:15 PM - 2:30 PM The Office of Research Integrity: Institutional Investigations, DIO Oversight, and Scientific Forensics John E. Dahlberg View Presentation Lessons Learned about Omics-based Predictive Tests from the Nevins Laboratory at Duke Gilbert S. Omenn View Presentation Inside Scientific Misconduct: Why Transparency Matters Adam Marcus View Presentation Discussion 263. NEI Grants Workshop: All about Funding Opportunity Announcements (FOAs) Moderator(s): Lore Anne McNicol (NEI) 1:00 PM - 2:30 PM; 611-614 1:00 PM - 1:20 PM 1:20 PM - 1:40 PM 1:40 PM - 2:00 PM 2:00 PM - 2:20 PM 2:20 PM - 2:30 PM View Session Details View Session Details FOAs: What? Ellen S. Liberman View Presentation FOAs: Why? Michael A. Steinmetz View Presentation FOAs: How to Read Them Houmam Araj View Presentation FOAs: How to Choose One Lore Anne McNicol View Presentation Discussion Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Showing 1 - 50 of 84 See More... TUESDAY, MAY 07, 2013 301. Gene Regulation: Transcription and Epigenetics Moderator(s): Shiming Chen (Washington University School of Medicine) and Noriko Esumi (Johns Hopkins Univ Sch of Med) 8:30 AM - 10:15 AM; 6A View Session Details 2612. Transcriptional and post-transcriptional regulation links RPE65, RLBP1, and RGR in the RPE Noriko Esumi; Tomohiro Masuda; Jun Wan; Karl J. Wahlin; Jared Iacovelli; Natalie Wolkow; Joshua L. Dunaief; Donald J. Zack; Jiang Qian View Presentation 8:45 AM - 9:00 AM 2613. GTF2IRD1 is a Dual-FunctionTranscription Factor that Promotes M Opsin Gene Expression and Suppresses S Opsin Gene Expression in M Cones Donald J. Zack; Anitha Yerrabelli; Xiaodong Zhang; Elizabeth A. Conner; Snorri S. Thorgeirsson; Anand Swaroop; Shiming Chen; Tomohiro Masuda View Presentation 9:00 AM - 9:15 AM 2614. Transcription and splicing associated protein NonO/p54nrb regulates rod specific genes including rhodopsin and their regulators required for rod differentiation and homeostasis Sharda P. Yadav; Hong Hao; Marie-Audrey I. Kautzmann ; Matthew Brooks; Jacob Nellissery; Anand Swaroop View Presentation 9:15 AM - 9:30 AM 2615. Correlating Whole Genome DNA Methylation Patterns with Retinal Expression and Alternative Splicing Jiang Qian; Jun Wan; Verity F. Oliver; Donald J. Zack; Shannath L. Merbs View Presentation 9:30 AM - 9:45 AM 2616. Histone marks predict cell plasticity of the adult human retinal pigment epithelium Timothy A. Blenkinsop; Alvaro Rada-Iglesias; Joanna Wysocka; Sally Temple View Presentation 9:45 AM - 10:00 AM 2617. The MLL1 Histone Methyltransferease is Essential for Development of Photoreceptor Function Diana S. Brightman; Ray Suzuki; Shiming Chen View Presentation 2618. Role of 5-hydroxymethylcytosine during postnatal retinal development 10:00 AM - 10:15 Stylianos Michalakis; Arshan Perera; Susanne Koch; Mirko Wagner; Lukas Windhager; AM Kerstin Nagel-Wolfrum; Tim M. Strom; Ralf Zimmer; Thomas Carell; Martin Biel View Presentation 8:30 AM - 8:45 AM 302. Clinical Studies/Trials Moderator(s): Mae Gordon (Washington Univ Sch of Med) and Neeru Gupta (University of Toronto) 8:30 AM - 10:15 AM; 6B 8:30 AM - 8:45 AM View Session Details 2619. The United Kingdom Glaucoma Treatment Study (UKGTS): baseline characteristics and main outcomes David F. Garway-Heath; Gerassimos Lascaratos; Catey Bunce; David P. Crabb; Richard A. Russell; Ameet Shah; Katsuyoshi Suzuki; Edward White; Francesca Amalfitano View Presentation 2620. Canadian Glaucoma Study 4: Neuroretinal Rim Area Change in Patients with Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 96 sur 222 Visual Field-based Endpoints and Interventions Rizwan Malik; Neil O'Leary; Frederick S. Mikelberg; Gordon A. Balazsi; Raymond P. LeBlanc; Mark R. Lesk; Marcelo T. Nicolela; Graham E. Trope; Balwantray C. Chauhan View Presentation 9:00 AM - 9:15 AM 2621. A Randomized, Phase II Study of Trabodenoson (INO-8875) in Adults with Ocular Hypertension (OHT) or Primary Open-Angle Glaucoma (POAG) Jonathan S. Myers; Kenneth N. Sall; Harvey DuBiner; Chaim Brickman; N. Slomowitz; William McVicar; Rudolf Baumgartner View Presentation 9:15 AM - 9:30 AM 2622. Association of poor eyedrop instillation technique and faster rate of visual field progression in patients under chronic glaucoma medical therapy Jimena Schmidt; Andres Gerhard; Militza Sanchez; Pablo Musa; David S. Friedman; Eugenio A. Maul View Presentation 9:30 AM - 9:45 AM 2623. Non-adherence in glaucoma and its association with satisfaction of glaucoma and medication information Heidi Cate; Debi Bhattacharya; Allan Clark; Richard Fordham ; Richard Holland; David C. Broadway View Presentation 2624. Protective effects of JNK inhibition in retinal ganglion cells and in retinal 9:45 AM - 10:00 AM ischemia/reperfusion injury Byung-Jin Kim; Yang Liu; Sean Silverman; Robert J. Wordinger; Richard T. Libby; IokHou Pang; Abbot F. Clark View Presentation 2625. Topical administration of MRZ-99030, a β-amyloid aggregation modulator, protects 10:00 AM - 10:15 retinal ganglion cells and axons in a rodent model of glaucoma AM Andreas Gravius; Kai-Uwe Klein; Leonard A. Levin; Wolf Lagreze; Nico Wegener; Wojciech Danysz View Presentation 8:45 AM - 9:00 AM 303. Metabolomics and Lipidomics: Metabolic Fingerprints Offer New Insights into Disease Pathogenesis with Potential for Life Changing Research Minisymposium Moderator(s): Usha Chakravarthy (Queens University of Belfast), Jennifer Kang Mieler (Illinois Institute of Technology) and Astrid Fletcher (London School of Hygiene & Tropical Med) 8:30 AM - 10:15 AM; 6C 8:30 AM - 8:35 AM View Session Details Introduction View Session Details 2630. Visual fields in patients with glaucoma: variability, outliers, and the power to detect change Paul H. Artes; Neil O'Leary; Balwantray C. Chauhan; Marcelo T. Nicolela; Lesya Shuba; Paul E. Rafuse View Presentation 8:45 AM - 9:00 AM 2631. Enhancement of a Risk Calculator to Assess Rates of Visual Field Progression in Treated Glaucoma Patients using Topographic Analysis Rafael L. Furlanetto; C. Gustavo De Moraes; Anastasia Slobodnick; Jeffrey M. Liebmann; Robert Ritch View Presentation 9:00 AM - 9:15 AM 2632. Key predictors of visual field test reliability Jason Ho; Sally Ameen; Laura Crawley; Eduardo M. Normando; M Francesca Cordeiro; Philip A. Bloom; Faisal Ahmed View Presentation 9:15 AM - 9:30 AM 2633. A New Index to Monitor Central Field Progression in Glaucoma Gustavo De Moraes; Rafael L. Furlanetto; Jeffrey M. Liebmann; Robert Ritch View Presentation 9:30 AM - 9:45 AM 2634. Determinants of Visual Field Reliability Pradeep Y. Ramulu; Michael V. Boland; Jiangxia Wang; Li Xu; Jamie Brown; David S. Friedman View Presentation 2635. Rates of Glaucomatous Visual Field Change in a Large Clinical Population 9:45 AM - 10:00 AM Balwantray C. Chauhan; Paul E. Rafuse; Lesya Shuba; Marcelo T. Nicolela; Paul H. Artes View Presentation 2636. The Effect of Stimulus Size on the Relation between Sensitivity and Variability in 10:00 AM - 10:15 Perimetry AM Stuart K. Gardiner; Deborah Goren; Casie Goldman; William H. Swanson; Shaban Demirel View Presentation 8:30 AM - 8:45 AM 305. Clinical Application of Ocular Imaging Moderator(s): Gadi Wollstein (University of Pittsburgh) and James Fujimoto (Massachusetts Inst of Technology) 8:30 AM - 10:15 AM; 606/607 8:30 AM - 8:45 AM 8:45 AM - 9:00 AM 9:00 AM - 9:15 AM Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary 2626. Metabolomics. Expanding Tools for Investigation of Chronic Diseases Christopher Elliott View Presentation 8:55 AM - 9:15 AM 2627. Methods of Metabolomic Analysis and Handling Complex Datasets Jeffrey M. Macdonald View Presentation 9:15 AM - 9:35 AM 2628. The Role of Metabolomics in Studying Complications of Diabetes and Cardiovascular Diseases Warwick Dunn View Presentation 9:35 AM - 9:55 AM 2629. Metabolomics and Retinal Diseases Milam A. Brantley View Presentation 9:55 AM - 10:15 AM Discussion 8:35 AM - 8:55 AM 304. Perimetry I Moderator(s): John Flanagan (Univ of Toronto,Toronto Western Hosp) and Joel Schuman (UPMC Eye Center/Univ of Pittsburgh) 8:30 AM - 10:15 AM; 6E Include in Itinerary View Session Details 2637. Three-dimensional Evaluation of Retinal Ganglion Cell Axon Regeneration, Pathfinding and Glial Reaction in Unsectioned Tissue Xueting Luo; Yadira Salgueiro; Samuel R. Beckerman; Vance P. Lemmon; Pantelis Tsoulfas; Kevin K. Park View Presentation 2638. Repeatability of Three-Dimensional (3D) Microstructural Parameters of the Lamina Cribrosa (LC) in Adaptive Optics Spectral-Domain Optical Coherence Tomography (AOSDOCT) Zach Nadler; Bo Wang; Gadi Wollstein; Daniel X. Hammer; R. D. Ferguson; Hiroshi Ishikawa; Richard A. Bilonick; Jessica E. Nevins; Larry Kagemann; Joel S. Schuman View Presentation 2639. Intrinsic Optical Signal Mapping of Localized Retinal Dysfunction Xincheng Yao; Qiuxiang Zhang; Rongwen Lu Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 97 sur 222 View Presentation 2640. Characteristics of Optic Nerve Development Using Hand-Held Ultra-High Resolution Spectral Domain Optical Coherence Tomography in Premature and Full-term Neonates Aarti Patel; Helena Lee; Viral Sheth; Gail Maconachie; Frank A. Proudlock; Rebecca J. McLean; Samira Anwar; Joe Fawke; Irene Gottlob View Presentation 9:30 AM - 9:45 AM 2641. Visualization and Automatic Diameter Evaluation of In Vivo Choroidal Vessels by High-Penetration Optical Coherence Tomography Yoshiaki Yasuno; Young-Joo Hong; Myeong Jin Ju; Masahiro Miura; Lian Duan View Presentation 9:45 AM - 10:00 AM 2642. Extended-imaging-depth (16mm) Spectral Domain OCT Operating at 1310-nm for Anterior Segment Biometry of the Human Eye Gongpu Lan; Peng Li; lin an; Douglas S. Malchow; Murray A. Johnstone; Ruikang K. Wang View Presentation 2643. In-vivo Confocal and two-photon fluorescence microscopy on the cornea of 10:00 AM - 10:15 diabetic and non-diabetic thy1 YFP mice AM Alexander Heisterkamp; Tobias Ehmke; Maria Reichard; Heike Weiss; Simone Baltrusch; Oliver Stachs View Presentation 9:15 AM - 9:30 AM 306. Protein Trafficking in Photoreceptors and Interactions Between the Retina and RPE Moderator(s): Nancy Philp (Thomas Jefferson University) and Vadim Arshavsky (Duke University) 8:30 AM - 10:15 AM; 611-614 View Session Details 2644. Outer Segment Targeting of R9AP in Mouse Rod Photoreceptors Jillian N. Pearring; Sidney Gospe; Sheila A. Baker; Vadim Y. Arshavsky View Presentation 8:45 AM - 9:00 AM 2645. The Drosophila SNARE Protein, Gos28, is Critical for Rhodopsin Transport and Photoreceptor Viability Nansi J. Colley; Erica E. Rosenbaum; Kimberely Brehm; Eva Vasiljevic View Presentation 9:00 AM - 9:15 AM 2646. Investigation of protease candidates for the release of soluble MerTK during photoreceptor outer segments phagocytosis by retinal pigment epithelial cells Celia Parinot; Jonathan Chatagnon; Emeline F. Nandrot View Presentation 9:15 AM - 9:30 AM 2647. MERTK regulation of the Rab GTPase effector GDI1 from the superfamily of GDI/CHM proteins Shameka Shelby; Kecia L. Feathers; Lin Jia; Frank Mei; Debra A. Thompson View Presentation 9:30 AM - 9:45 AM 2648. Modulation of the Daily Rhythm in Disc Shedding by Melatonin in the Mouse Gianluca Tosini; Virginie Laurent; Kenkichi Baba; Susumu Hiragaki; Susana ContrerasAlcantara; David Hicks View Presentation 2649. Metabolic Coupling Between the Retinal Pigment Epithelium (RPE) and Retina 9:45 AM - 10:00 AM Jeffrey Adijanto; Erin L. Seifert; Cynthia Moffat; Arvydas Maminishkis; Nancy J. Philp View Presentation 2650. Global identification of RPE phagocytosis ligands by phagoligandomics 10:00 AM - 10:15 Wei Li; Nora B. Caberoy; Gabriela S. Alvarado; Hui Wang; Feng Wang; Rui Chen AM View Presentation 8:30 AM - 8:45 AM 307. Glaucoma Epidemiology: Teasing Out Mechanisms and Understanding the Burden Moderator(s): Linda Zangwill (Univ of California-San Diego) and Anthony Khawaja (University of Cambridge) 8:30 AM - 10:15 AM; 615-617 View Session Details 2651. Clarifying the role of ATOH7 in glaucoma endophenotypes Ananth C. Viswanathan; Cristina Venturini; Pirro G. Hysi; Abhishek Nag; Ekaterina Yonova; Jie Wang; Tien Y. Wong; Paul R. Healey; Paul Mitchell; Christopher J. Hammond View Presentation 8:45 AM - 9:00 AM 2652. Pseudoexfoliation: Normative Data and Associations. The Beijing Eye Study 2011 Qisheng You; Ya Xing Wang; Liang Xu; Jost B. Jonas View Presentation 9:00 AM - 9:15 AM 2653. The association of pseudoexfoliation syndrome (PEX) with cardiovascular (CVD) and cerebrovascular (CVA) disease: a systematic review and meta-analysis Helen Chung; Sourabh Arora; Karim F. Damji; Ezekiel Weis View Presentation 9:15 AM - 9:30 AM 2654. Corneal hysteresis and glaucoma-related quantitative traits in the EPIC-Norfolk Eye Study Anthony P. Khawaja; Michelle P. Chan; David C. Broadway; David F. Garway-Heath; Robert Luben; Kay-Tee Khaw; Paul J. Foster View Presentation 9:30 AM - 9:45 AM 2655. Glaucomatous progression in the African Descent and Glaucoma Evaluation Study (ADAGES) Linda M. Zangwill; Naira Khachatryan; Sonia Jain; Feng He; Felipe A. Medeiros; Christopher Bowd; Renato Lisboa; Robert N. Weinreb; Jeffrey M. Liebmann; Christopher A. Girkin View Presentation 9:45 AM - 10:00 AM 2656. Number of People with Glaucoma in Asia in 2020 and 2040: A Hierarchical Bayesian Meta-Analysis Xiang LI; Errol W. Chan; Jiemin Liao; Tien Y. Wong; Tin Aung; Ching-Yu Cheng View Presentation 2657. The Cost of Glaucoma Care Provided to a Sample of Medicare Beneficiaries from 10:00 AM - 10:15 2002--2009 AM Harry Quigley; Sandra D. Cassard; Emily W. Gower; Pradeep Y. Ramulu; Henry D. Jampel; David S. Friedman View Presentation 8:30 AM - 8:45 AM 308. Binocular Vision and Stereopsis View Session Details Moderator(s): Robert Hess (McGill University) and Peter Bex (Harvard Medical School) 8:30 AM - 10:15 AM; TCC LL 4/5 8:30 AM - 8:45 AM 8:45 AM - 9:00 AM 9:00 AM - 9:15 AM 9:15 AM - 9:30 AM 2658. Mechanisms underlying global stereopsis in fovea and periphery Robert F. Hess; Nirel Witz View Presentation 2659. Effect of inter-ocular differences in blur on spatial and stereo-resolution Sowmya Ravikumar; Bjorn Vlaskamp; Martin S. Banks View Presentation 2660. Binocular combination of optically-induced asymmetric interocular blur Aixa Alarcon; Len Zheleznyak; Martin S. Banks; Geunyoung Yoon View Presentation 2661. The Effect of Unilateral Mean Luminance on Binocular Combination in normal and amblyopic vision Chang-Bing Huang; Jiawei Zhou; Robert F. Hess View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 98 sur 222 2662. The Contribution of Perspective, Blur and Disparity to Depth Perception in Natural Vision Guido Maiello; Manuela Chessa; Fabio Solari; Peter Bex View Presentation 9:45 AM - 10:00 AM 2663. Rapid assessment of core visual deficits in amblyopia MiYoung Kwon; Luis A. Lesmes; Alexandra Miller; Melanie Kazlas; Michael Dorr; David G. Hunter; Zhong-Lin Lu; Peter Bex View Presentation 2664. Binocular Visual Acuity with Combined Correction of Spherical and Longitudinal 10:00 AM - 10:15 Chromatic Aberrations AM Christina Schwarz; Silvestre Manzanera; Pedro M. Prieto; Pablo Artal View Presentation 9:30 AM - 9:45 AM 309. Dry Eye and Lacrimal Gland III Moderator(s): David Sullivan (Schepens Eye Res Inst/Harvard Med School) and Pablo Argueso (Schepens Eye Rsrch Inst, MEEI, HMS) 8:30 AM - 10:15 AM; TCC 303 View Session Details 2665. Prevalence and Determinants of Dry Eye Disease in a British Female Cohort Jelle Vehof; Diana Kozareva; Pirro G. Hysi; Samantha J. Fahy; Kenan Direk; Tim Spector; Christopher J. Hammond View Presentation 8:45 AM - 9:00 AM 2666. Role of galectin-3 in dry eye disease Yuichi Uchino; Jerome Mauris; Julia Dieckow; Ashley M. Woodward; Francisco Amparo; Reza Dana; Flavio Mantelli; Pablo Argueso View Presentation 2667. Topical administration of lacritin promotes tear secretion and improves ocular 9:00 AM - 9:15 AM surface integrity in a mouse model of autoimmune dry eye Thirugnana Vijmasi; Feeling Yu Ting Chen; Robert L. McKown; Gordon W. Laurie; Nancy A. McNamara View Presentation 2668. Bridging ocular therapeutics and contact lenses via thermo-responsive protein 9:15 AM - 9:30 AM polymers Wan Wang; Pu Shi; Suhaas Aluri; Pang-Yu Hsueh; Maria C. Edman; Denise S. Ryan; Robert L. McKown; Sarah F. Hamm-Alvarez; Gordon W. Laurie; John A. MacKay View Presentation 9:30 AM - 9:45 AM 2669. Lifitegrast 5.0% Ophthalmic Solution Reduces Ocular Surface Staining and Improves Symptoms in Patients with Dry Eye Disease: Results of a Phase 3 Study (OPUS-1) Charles P. Semba; Gail L. Torkildsen; Francis A. D'Ambrosio; John Lonsdale; Eugene B. McLaurin; Richard A. Eiferman; Kathryn S. Kennedy; John D. Sheppard View Presentation 9:45 AM - 10:00 AM 2670. Effects of L-carnitine, Erythritol and Betaine on Inflammatory Markers in Primary Human Corneal Epithelial Cells Exposed to Hyperosmotic Stress Xia Hua; Zhitao Su; Ruzhi Deng; Jing Lin; De-Quan Li; Stephen C. Pflugfelder View Presentation 2671. Age-related changes in the meibomian gland revealed by Immunofluorescent 10:00 AM - 10:15 Computed Tomography AM Geraint J. Parfitt; Yilu Xie; Donald J. Brown; James V. Jester View Presentation 8:30 AM - 8:45 AM 310. Visual Behavior, Disease, and Restoration Moderator(s): Alexander Sher (University of California, Santa Cruz) and Maureen McCall (University of Louisville ) 8:30 AM - 10:15 AM; TCC 304 View Session Details Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary 8:30 AM - 8:30 AM moderator options: Paul Gamlin, Anand Swaroop, Alexander Sher, Corinne Beier? Include in Itinerary 8:30 AM - 8:30 AM alternates: Ratliff Include in Itinerary 8:30 AM - 8:45 AM 2672. Exogenous zinc ions interrupt visual signal transmission from photoreceptors to bipolar cells and reduce retinal TRPM1 expression in mouse Bo Lei; Yu Liu; Tao Lin; Hongxia Yang View Presentation 8:45 AM - 9:00 AM 2673. Molecular coupling between TRPV4 and aquaporin 4 channels mediates osmosensation in Müller glia David Krizaj; Daniel A. Ryskamp; Andrew O. Jo; Alan Verkman; Nanna Macaulay View Presentation 9:00 AM - 9:15 AM 2674. Nonlinear Pupil Responses to Rod and Cone Inputs Dingcai Cao; Pablo A. Barrionuevo; Nathaniel Nicandro; J Jason McAnany; Andrew J. Zele; Paul D. Gamlin View Presentation 9:15 AM - 9:30 AM 2675. Diabetic retinopathy alters retinal ganglion cell function and light responsiveness in the Ins2Akita mouse model of diabetes Rene C. Renteria; Nikolay P. Akimov; Songqing Lu View Presentation 9:30 AM - 9:45 AM 2676. Effects of Nrl knockout on visual signal in mouse retina Yichao Li; Jerome E. Roger; Rivka A. Rachel; Anand Swaroop; Haohua Qian View Presentation 9:45 AM - 10:00 AM 2677. Constructive Retinal Plasticity After Selective Ablation of the Photoreceptors Corinne N. Beier; Bryan W. Jones; Philip Huie; Yannis M. Paulus; Daniel Lavinsky; LohShan B. Leung; Hiroyuki Nomoto; Robert E. Marc; Daniel V. Palanker; Alexander Sher View Presentation 2678. Optogenetic Targeting of ON and OFF bipolar cells for vision restoration 10:00 AM - 10:15 Jun-Kyo F. Suh; Jin Mo Kim; Hyuk-June Moon; Hyun-Joon Shin; Eunmi Hwang; Dong AM Hoon Kang; Changjoon J. Lee View Presentation 311. Diabetic Retinopathy and Vascular Biology I Moderator(s): Nader Sheibani (Univ of Wisconsin-Madison) and Bruce Berkowitz (Wayne State Univ Sch of Med) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 2679 - A0001. Lack of CX3CR1 Prevents Retinal Vascular Rarefaction Associated with ER Stress, Neuronal Degeneration, and Diabetes Shoujian Wang; Christine M. Sorenson; Nader Sheibani View Presentation 2680 - A0002. Impaired Chromophore Availability in the Diabetic Retina: Impact on Visual Performance Bruce A. Berkowitz; Timothy S. Kern; Vladimir J. Kefalov; Johannes Von Lintig; Robin Roberts; David Bissig View Presentation 2681 - A0003. Hyperglycemia in the newborn rat induces retinal vascular growth retardation and the recruitment of inflammatory macrophages to the retina Xavier P. Guillonneau; Elsa Kermorvant; Delphine Lenne; Sophie Lavalette; William Raoul; Bertrand Calippe; Florian Sennlaub View Presentation 2682 - A0004. Shedding of Vascular Adhesion Protein-1 by VEGF Stimulation under High Glucose Condition Shiho Namba; Kousuke Noda; Miyuki Murata; Atsuhiro Kanda; Susumu Ishida Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 99 sur 222 View Presentation 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 2683 - A0005. The effect of preterm birth on normal retinal vascular development and oxygen-induced retinopathy in neonatal rat Yusheng Wang; Rong Li View Presentation 2684 - A0006. Specific Role and Regulation of αA- and αB-Crystallins in Diabetic Retinopathy Patrice E. Fort; Sean A. Grafton; Katelyn M. Roth View Presentation 2685 - A0007. Inhibition of Calcineurin/NFAT signaling in retinal endothelial cells reduces VEGF-induced inflammatory response Sara R. Savage; Colin A. Bretz; John S. Penn View Presentation 2686 - A0008. Expression of Inflammatory Mediators in Eyes of Spontaneously Type-2 Diabetic Monkeys Imran A. Bhutto; Joseph R. Yates; Mary A. Johnson; Carol Merges; Barbara C. Hansen; Gerard A. Lutty View Presentation 2687 - A0009. High Glucose-Induced Connexin 43 (Cx43) Downregulation Modulates Rho/Rho kinase (ROCK) Signaling and Promotes Apoptosis in Retinal Endothelial Cells Tetsuya Muto; Sayon Roy View Presentation 2688 - A0010. Reduced Connexin 43 (Cx43) plays a role in the development of vascular lesions in human diabetic retinopathy Thomas Tien; Tetsuya Muto; Elliott H. Sohn; Robert F. Mullins; Sayon Roy View Presentation 2689 - A0011. Connexin 43 (Cx43) Upregulation Protects Retinal Endothelial Cells Against High Glucose Insult Kevin F. Barrette; Lucky Challyandra; Sayon Roy View Presentation 2690 - A0012. Purinergic vasotoxicity in retinal capillaries Maho Shibata; Atsuko Nakaizumi; Ting Zhang; Eisuke Ishizaki; Masanori Fukumoto; Alma Barajas-Espinosa; Donald G. Puro View Presentation 2691 - A0013. Accelerated retinal microvasculopathy in BMAL1 deficient mice Ashay D. Bhatwadekar; Yanpeng Diao; Jude Al-Sabah; Sergio Caballero; Choogon Lee; Mark S. Segal; Maria B. Grant View Presentation 2692 - A0014. Upregulation of activator protein 1 (c-Fos/c-Jun) and c-Jun N-terminal kinase associated with neuronal cell death in retinas of diabetic patients Toshiyuki Oshitari; Shuichi Yamamoto; Sayon Roy View Presentation 2693 - A0015. Heparanase Regulates Transcription Activity of VEGF Gene in Human Retinal Microvascular Endothelial Cells induced by hyperglucose Jie Hu View Presentation 2694 - A0016. Telmisartan increases the levels of brain derived neurotrophic factor and glutathione in the retina of streptozotocin-induced diabetic rats Mohammad S. Ola; Mohd I. Nawaz; Hatem M. Abuohashish; Abdullah S. Alhomaida; Salim S. Al-Rejai; Mohammed M. Ahmed View Presentation 2695 - A0017. EFFECT OF EXPERIMENTAL DIABETIC RETINOPATHY ON THE NONIMAGE FORMING VISUAL SYSTEM Pablo h. Sande; Nuria de Zavalia; Nicolas A. Belforte; Damian Dorfman; Ruth E. Rosenstein; Diego C. Fernandez View Presentation 2696 - A0018. Vasoinhibins reduce the increase of retinal vasopermeability associated with diabetes: contribution of the kallikrein-kinin system David Arredondo; Olivia Baldivieso Hurtado; Daniel Ochoa-Contreras; Carmen Clapp; Stephanie Thebault View Presentation 2697 - A0019. The imbalance of Th17 and Treg cells in the retinopathy of diabetic rat model Chang He; Yuying Sun; Xiao Hu; Jing Wang; Lu Wang; Yizhi Liu; Xialin Liu View Presentation 2698 - A0020. NFAT signaling induces upregulation of cytokines that promote the pathology of diabetic retinopathy Colin A. Bretz; John S. Penn View Presentation 2699 - A0021. Role of proNGF/p75NTR mediated RhoA activation in diabetes-induced BRB breakdown Barbara A. Mysona; Suraporn Matragoon; Azza B. El-Remessy View Presentation 2700 - A0022. Dicer 1 loss and increased Alu RNA in the pathogenesis of diabetic retinopathy Yuanqing Yan; Tatiana Salazar; James M. Dominguez; Dung V. Nguyen; Sergio Li Calzi; Ashay D. Bhatwadekar; Julia V. Busik; Michael E. Boulton; Maria B. Grant View Presentation 2701 - A0023. Role of TXNIP in High fat Diet-induced Inflammasome Activation in Retinal Endothelial Cells Islam N. Mohamed; Modesto A. Rojas; Ruth B. Caldwell; Adviye Ergul; Azza B. ElRemessy View Presentation 2702 - A0024. Paracrine Effects of Adipose Stromal Cell Conditioned Media on Retina: A Cell-free Therapy for Retinal Diseases Gangaraju Rajashekhar; Chandrika Abburi; Raj Maturi; Alon Harris; Timothy S. Kern; Keith L. March View Presentation 2703 - A0025. Differentiating vitreous proteomes in proliferative diabetic retinopathy using high-performance liquid chromatography coupled to tandem mass spectrometry Hao Wang; Le Feng; Fang Wang View Presentation 2704 - A0026. Neuronal Socs3 deficiency promotes pathologic retinal angiogenesis Ye Sun; Jean-Sebastien Joyal; Andreas Stahl; Christian G. Hurst; Zhenghao Cui; Lucy Evans; Zhongjie Fu; Zhuo Shao; Jing Chen; Lois E. Smith View Presentation 2705 - A0027. VEGF165b reduces blood vessel permeability in diabetic retinas Nikita Ved; Richard Hulse; Lucy F. Donaldson; James W. Bainbridge; David O. Bates View Presentation 2706 - A0028. Role of the Receptor for Advanced Glycation Endproducts (RAGE) in retinal vasodegenerative pathology during diabetes Carmel M. McVicar; Micheal S. Ward; Liza Colhoun; Darren Conway; Hans-Peter Hammes; Alan W. Stitt View Presentation 312. Gene Therapy Moderator(s): Ashim Mitra (University of Missouri-Kansas City) and Naj Sharif (Alcon Research Ltd ) View Session Details Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary 28/03/2013 Abstract Central Page 100 sur 222 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 2707 - A0151. Corrective Gene Therapy for RPGR-XLRP Rescues a Canine Model at Mid-Stage Disease William A. Beltran; Artur V. Cideciyan; Alfred S. Lewin; Simone Iwabe; Sanford L. Boye; William W. Hauswirth; Samuel G. Jacobson; Gustavo D. Aguirre View Presentation 8:30 AM - 10:15 AM 2708 - A0152. RECOVERY OF VISUAL FUNCTION FOLLOWING GENE THERAPY IN A LARGE ANIMAL MODEL OF CNGA3 ACHROMATOPSIA Edward Averbukh; Ron Ofri; Elisha Gootwine; Raaya Ezra-Elia; Hen H. Honig; Alexander Rosov ; Esther Yamin; Alexey Obolensky; William W. Hauswirth; Eyal Banin View Presentation 8:30 AM - 10:15 AM 2709 - A0153. Phase I Gene Therapy Trial in Israeli Patients with Leber Congenital Amaurosis Caused by a Founder RPE65 Mutation: Safety and Efficacy Update with Up to Two Years of Follow-up Eyal Banin; Alexey Obolensky; Yitzhak Hemo; Devora Marks-Ohana; Malka Sela; Esther Yamin; William W. Hauswirth; Samuel G. Jacobson; Dror Sharon View Presentation 8:30 AM - 10:15 AM 2710 - A0154. AAV Mediated Gene Transfer Restores Retinal and Visual Function in Lebercilin-/- (LCA5) Mice Daniel C. Chung; Jeannette Bennicelli; Adam Wojno; Nicoletta A. Commins; Robert W. Bloom; Daniel J. Bennett; Thu T. Duong; Meera Sivalingam; Arkady Lyubarsky; Jean Bennett View Presentation 8:30 AM - 10:15 AM 2711 - A0155. AAV-Mediated Expression of Secreted Human Ciliary Neurotropic Factor (hCNTF) Leads to Long-Term Preservation of Cone Photoreceptors in an Autosomal Recessive Model of Retinitis Pigmentosa Daniel M. Lipinski; Alun R. Barnard; Mandeep S. Singh; Edward Lee; Robert E. MacLaren View Presentation 8:30 AM - 10:15 AM 2712 - A0156. Ultrahigh Resolution Mouse Optical Coherence Tomography to Aid Retinal Gene Therapy Research Mark C. Butler; Tiffany A. Kolniak; Jack Sullivan View Presentation 8:30 AM - 10:15 AM 2713 - A0157. Human MiniPromoters with Restricted-Retinal Expression when Docked in the Mouse Genome Show the Same Restricted Expression when Delivered in AdenoAssociated Virus (AAV) Elizabeth M. Simpson; Charles N. de Leeuw; Frank M. Dyka; Sanford L. Boye; Michelle Zhou; Lisa Borretta; Robert Holt; Daniel Goldowitz; William W. Hauswirth; Wyeth Wasserman View Presentation 8:30 AM - 10:15 AM 2714 - A0158. Sustained Transgene Expression with Non-viral Gene Transfer Following Chitosan Mediated Delivery Ana Vanessa Oliveira; Gabriela A. Silva; Daniel C. Chung View Presentation 8:30 AM - 10:15 AM 2715 - A0159. AAV-mediated Lpcat1 gene replacement therapy rescues retinal degeneration in rd11 mice Xufeng Dai; Juanjuan Han; Zi-Bing Jin; Yan Qi; Jie Li; Wen-Tao Deng; Bo Chang; William W. Hauswirth; Ji-Jing Pang View Presentation 8:30 AM - 10:15 AM 2716 - A0160. Enhancement of AAV2-mediated retinal transduction in diabetic rats Nundehui Díaz-Lezama; Zhijian Wu; Mayda Ramírez; Bibiana Moreno-Carranza; Gonzalo Martinez de la Escalera; Peter Colosi; Carmen Clapp View Presentation 8:30 AM - 10:15 AM 2717 - A0161. Ex vivo gene transfer of anti-angiogenic soluble Flt-1 to corneal epithelial cells sheets suitable for ocular surface reconstruction Jingbo Liu; Victor H. Guaiquil; Aihong Liu; Mark Rosenblatt View Presentation 8:30 AM - 10:15 AM 2718 - A0162. Comparison of Adeno-Associated Viral Vector Serotypes for Gene Transfer To Corneal Endothelial Cells Thomas A. Fuchsluger; Christian Mueller; Reza Dana View Presentation 2719 - A0163. Effect of intraviteal injection of AAV9.TGFβ2 on the expression of anterior Withdrawn segment and intraocular pressure in rabbits Guilin Zhan; Chris Long; Allan Shepard; Nasreen Jacobson; Richard Ornberg; Yu Wang; Shutong Cao; Ganesh Prasanna View Presentation 8:30 AM - 10:15 AM 2720 - A0164. Changes in S and L/M cone opsin expression in the RPE65 dog model following AAV mediated gene addition therapy Knut Stieger; Daniela Klein; Alexandra Mendes-Madeira; Fabienne Rolling; Silke Haverkamp; Birgit Lorenz View Presentation 8:30 AM - 10:15 AM 2721 - A0165. Natural History of the CNGB3/NRL Double Knock-Out Mouse William W. Hauswirth; Seok-Hong Min; Sanford L. Boye; Daniel Kasuga; Qing Ruan; Jingfen Sun; Mai Tram Phan; Shannon E. Boye; Christine N. Kay View Presentation 8:30 AM - 10:15 AM 2722 - A0166. Subretinal Injection of AAV2-CMV-hEPO to Diabetic Retina is Protective and Safe Hua Xu; Jingfa Zhang; Limei Zhang; Limin Gu; Lixia Lu; Weiye Li; Guo-Tong Xu View Presentation 8:30 AM - 10:15 AM 2723 - A0167. AAV-mediated gene therapy restores cone function in the Cnga3/Nrl double knockout mouse Ji-Jing Pang; Ye Tao; Sanford L. Boye; Jie Li; Wen-Tao Deng; Xi-Qin Ding; Stylianos Michalakis; Martin Biel; Shannon E. Boye; William W. Hauswirth View Presentation 8:30 AM - 10:15 AM 2724 - A0168. Gene Delivery of ATP6 by A Mitochondrial Targeting Sequence Modification of AAV Capsid VP2 Rescues Cells with Mutated T8993G MtDNA Responsible for Neuropathy Ataxia and Retinitis Pigmentosa Huijun Yuan; Hong Yu; John Guy View Presentation 8:30 AM - 10:15 AM 2725 - A0169. Effective delivery of small interfering RNA to mouse cornea by eye drops Kaili Wu; Zhongting Li; Fang Duan; Jingyu Liao; Qiang Huang View Presentation 8:30 AM - 10:15 AM 2726 - A0170. Targeted Suppression of Human Adenovirus DNA-polymerase Gene by RNA Interference Natalia Nikitenko; Anastasia Klimova; Pavel Spirin; Peter Groitl; Thomas Speiseder; Vladimir Prassolov View Presentation 8:30 AM - 10:15 AM 2727 - A0171. Evaluation of Influenza Associated Virus (IAV)-based replicationincompetent for Ocular Delivery of microRNAS Coralia C. Luna; Benjamin tenOever; Guorong Li; Sonja Schmid; Pratap Challa; David L. Epstein; Jianming Qiu; Pedro Gonzalez View Presentation 8:30 AM - 10:15 AM 2728 - A0172. LONG-TERM PROTECTION BY COMPLEMENT REGULATORY PROTEIN CRRY IN A MOUSE MODEL OF LIPOFUSCIN-MEDIATED RETINAL DEGENERATION Shanta Sarfare; Anita Kim; Zhichun Jiang; Marcia B. Lloyd; Shannan R. Eddington; Samer Habib; Dean Bok; Steven Nusinowitz; Gabriel H. Travis; Roxana A. Radu View Presentation 8:30 AM - 10:15 AM 2729 - A0173. Testing siRNAs for use in a rapidly progressing model of autosomal dominant retinitis pigmentosa Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 101 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Brian P. Rossmiller; Haoyu Mao; Alfred S. Lewin View Presentation 2730 - A0174. Gene Therapy for CEP290-associated LCA in Patient-Derived Induced Pluripotent Stem Cells Erin R. Burnight; Emily E. Kaalberg; Mari E. Eyestone; Jeremy Hoffman; Christine M. Haas; Robert F. Mullins; Edwin M. Stone; Budd A. Tucker View Presentation 2731 - A0175. AAV8 mediated gene therapy for corneal cystinosis Duy H. Nguyen; Hongjun Du; Matthew Bedell; Seanna Grob; Jing Luo; John L. Quach; Peter Shaw; Stephanie Cherqui; Kang Zhang View Presentation 2732 - A0176. Tropisms of AAV for Subretinal Delivery to the Neonatal Mouse Retina and Its Application for In Vivo Rescue of the Crx Knockout Retina Satoshi Watanabe; Rikako Sanuki; Shinji Ueno; Takahisa Furukawa View Presentation 2733 - A0177. Accessibility of Retinal Cells to Different AAV Serotypes After Intravitreal Injection in Old Versus New World Primates Maureen Neitz; Anita E. Hendrickson; Michael Lukason; Jay Neitz; Daniel E. Possin; Gelareh Abedi; Jing Huang; Abraham Scaria; Sam Wadsworth View Presentation 2734 - A0178. Transfer of TACSTD2 Gene into Corneal Epithelial Cells of Gelatinous Drop-Like Corneal Dystrophy and Its Functional Expression Toru Matsunaga; Koji Kitazawa; Kenta Yamasaki; Takao Sato; Yasuo Watanabe; Toshinari Funaki; Akira Matsuda; Nobuyuki Ebihara; Satoshi Kawasaki; Akira Murakami View Presentation 2735 - A0179. Transduction Profile of Anterior Chamber-injected Capsid Mutated Selfcomplementary Adeno-Associated Virus Type 2 in Rodents Barbara Bogner; Sanford L. Boye; Seok-Hong Min; James J. Peterson; Qing Ruan; Vince Chiodo; Renee C. Ryals; Herbert A. Reitsamer; William W. Hauswirth; Shannon E. Boye View Presentation 2736 - A0180. Glycosidic Enzymes Enhance Retinal Transduction Following Intravitreal Delivery of AAV2 Jasmina Cehajic-Kapetanovic; Annette Allen; Paul N. Bishop; Robert Lucas View Presentation 2737 - A0181. Antisense oligonucleotide-based therapy for CEP290-associated LCA Alejandro Garanto; Frans P. Cremers; Rob W. Collin View Presentation 2738 - A0182. Mitochondrial Gene Therapy for G11778A LHON: Safety of Human ND4 in Nonhuman Primates and Expression in Ex Vivo Human Eyes Rajeshwari D. Koilkonda; David T. Tse; William W. Hauswirth; Vince Chiodo; Sanford L. Boye; Martha Neuringer; Tim Stout; John Guy View Presentation 2739 - A0183. Dual Adeno-associated virus vectors for large cDNA gene replacement therapy Frank M. Dyka; Sanford L. Boye; Vince Chiodo; Shannon E. Boye; William W. Hauswirth View Presentation 2740 - A0184. A comparison of the effects of subretinal injection of scAAV2-CMV-GFP on retinal structure, visual function, and GFP expression by two injectors Hui Li; Stephen H. Poor; Chad E. Bigelow; Vivian Choi; Shawn Hanks; Joanna Vrouvlianis; Michael Maker; Steve Louie; Sha-Mei Liao; Bruce D. Jaffee View Presentation 2741 - A0185. Glaucoma-GT, a novel gene therapy treatment for primary open-angle glaucoma Scott Ellis; Katie M. Binley; Vicky Scripps; Sharifah Iqball; Stuart M. Naylor; Kyriacos Mitrophanous View Presentation 2742 - A0186. Functional Biomarkers For Successful Molecular Therapy Of The Outer Retina In Retinal Degenerations Vithiyanjali Sothilingam; Marina Garcia Garrido; Christina Seide; Susanne Koch; Stylianos Michalakis; Martin Biel; Naoyuki Tanimoto; Mathias W. Seeliger View Presentation 2743 - A0187. In Vivo Quantification Of Photoreceptor Transduction Efficiency Using Novel Modified AAV Capsids Renee C. Ryals; Christine N. Kay; Sanford L. Boye; Seok-Hong Min; Andrea E. Ayala; William W. Hauswirth; Shannon E. Boye View Presentation 2744 - A0188. The LentiVector® Gene Therapy Platform for Ocular Disease: a clinical update Kyriacos Mitrophanous; Scott Ellis; James Miskin; Katie M. Binley; Michelle Kelleher; Cherry A. Lucas; Stuart M. Naylor View Presentation 2745 - A0189. Assessment of Intravitreal AAV-TEAD4 Isoforms in the OIR Model Matthew Hartzell; Andrew J. Stempel; Trevor J. McFarland; Binoy Appukuttan; Tim Stout View Presentation 2746 - A0190. AAV-mediated Combination Therapy of Neurotrophic and Anti-Apoptotic Factors in a Mouse Model of Inherited Retinal Degeneration Cecile Fortuny; Leah C. Byrne; Deniz Dalkara; Trevor S. Lee; Bilge Esin Ozturk View Presentation 313. Low Vision Rehabilitation Moderator(s): Gislin Dagnelie (Johns Hopkins Univ) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM View Session Details 2747 - B0001. Measuring reading speed: a comparison of reading paragraphs and single sentences Susanne Trauzettel-Klosinski; Elke K. Altpeter; Tobias Marx; Nhung Nguyen View Presentation 8:30 AM - 10:15 AM 2748 - B0002. Properties of the Dutch Reading Charts Ger v. Van Rens; Tamara Verkerk Brussee; Edwin Klerkx; Ruth v. Nispen View Presentation 8:30 AM - 10:15 AM 2749 - B0003. iPad vs Closed Circuit Television Low Vision Reading Rates and Preferences Alex Zemke; Danielle Irvine; John Coalter; Walter M. Jay View Presentation 8:30 AM - 10:15 AM 2750 - B0004. Reading performance in low-vision patients using a low-cost portable reading system prototype Adriana Berezovsky; Vagner R. dos Santos; Nívea N. Cavascan; Solange R. Salomao View Presentation 8:30 AM - 10:15 AM 2751 - B0005. Improving reading speed in peripheral vision through a non-task-based training Deyue Yu View Presentation 2752. Effect of Decreased Lighting on Visual Acuity in Normal Subjects Donald C. Withdrawn Fletcher MD; California Pacific Medical Center Dept. of Ophthalmology and SmithKettlewell Eye Research Institute. Laura Walker Renninger; Smith-Kettlewell Eye Research Institute David T. Hamilton View Presentation 8:30 AM - 10:15 AM 2753 - B0007. Luminance in Acuity and Reading Performance of Low Vision Patients Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 102 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Withdrawn 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Donald C. Fletcher; Laura Renninger; Ronald A. Schuchard View Presentation 2754 - B0008. SK-Read performance as a predictor of handwriting difficulty in low vision patients Ken Downes; Donald C. Fletcher; Laura Renninger View Presentation 2755 - B0009. Using Mirametrix Eye Tracking Technology to Evaluate Eccentric Reading Joseph J. Zinkovich; Erika Anderson; Erin Doxtader; Michelle Nguyen View Presentation 2756 - B0010. Search during Word Recognition in Visual Noise with the Laser Scanning Digital Camera Stimulator Elli J. Kollbaum; Christopher A. Clark; Bryan P. Haggerty; Benno L. Petrig; Ann E. Elsner View Presentation 2757 - B0011. Low-power Half Lens Prisms For The Rehabilitation Of Hemianopia Giovanni Sato; Roberta Rizzo; Gianfrancesco M. Villani View Presentation 2758 - B0012. Peripheral Prisms Increase Blindside Eye And Head Scanning Movements During Outdoor Walking In Hemianopes: Preliminary Results Matteo Tomasi; Jeffrey Churchill; Jean Paul Wiegand; Kevin Houston; Eli Peli; Alexandra R. Bowers; Gang Luo View Presentation 2759 - B0013. Perceptual-motor adaptation in hemianopes wearing peripheral prisms is possible: Preliminary results Kevin Houston; Jeffrey Churchill; Jean Paul Wiegand; Eli Peli; Gang Luo; Robert B. Goldstein; Russell L. Woods; Alexandra R. Bowers View Presentation 2760 - B0014. Contrast Sensitivity (CS) test-retest reliability and consistency with Vector Vision CSV-1000LVand CSV-1000HGT in patients with Albinism Maria Cucuras; Susan Kelly; Faheemah Saeed View Presentation 2761 - B0015. Analyses of contrast sensitivity assessments over time: A pilot study Xi Chen; Luis A. Lesmes; Jennifer Wallis; Thomas S. Wallis; Mary Lou Jackson; Peter Bex View Presentation 2762 - B0016. The Reliability of the quick CSF Method for Contrast Sensitivity Assessment in Low Vision Luis A. Lesmes; Jennifer Wallis; Mary Lou Jackson; Peter Bex View Presentation 2763 - B0017. Contrast Sensitivity Measurement in the Pediatric Low Vision Setting Gregory R. Hopkins; Angela M. Brown View Presentation 2764 - B0018. Feedback measures for a wearable visual aid designed for the visually impaired Aminat Adebiyi; James D. Weiland; Carey Zhang; Kaveri Thakoor View Presentation 2765 - B0019. LOCOMOTION IN LOW LUMINANCE WITH NON IMMERSIVE HEAD MOUNTED DEVICE FOR PATIENTS WITH NIGHT BLINDNESS Coen Cecilia; Caroline Chauvire; Guillaume Le Gall; Arnaud Koustanai; Marion Swital; Laurence Bernardini; Philippe Chaumet-Riffaud; Saddek Mohand-Said; Jose A. Sahel; Avinoam B. Safran View Presentation 2766 - B0020. Object identification by retinitis pigmentosa patients in dim light, using a Head Mounted Display Marion Swital; Coen Cecilia; Caroline Chauvire; Arnaud Koustanai; Guillaume Le Gall; Sihem Kime; Philippe Chaumet-Riffaud; Saddek Mohand-Said; Jose A. Sahel; Avinoam B. Safran View Presentation 2767 - B0021. Sensitivity recovery following a bleach; a dual “smiley” arc stimulus technique for studying abnormal dark adaptation Humza J. Tahir; Ian J. Murray; David Carden; Neil R. Parry View Presentation 2768 - B0022. Darks are detected faster and more accurately than lights in normal subjects and patients with moderate glaucoma Linxi Zhao; Mitchell W. Dul; Jose M. Alonso; Stanley J. Komban; Qasim Zaidi View Presentation 2769 - B0023. Is visual exploration training beneficial in tunnel vision? Iliya V. Ivanov; Annika F. Vollmer; Nhung Nguyen; Susanne Trauzettel-Klosinski View Presentation 2770 - B0024. Is Vernier Acuity more Sensitive than Grating Acuity to Visual Impairment in Adolescents? Huizi Kelly Yin; Barry S. Kran; Darick Wright; Donna D. Bent; Li Deng; Dale L. Mayer View Presentation 2771 - B0025. Evaluating the Effectiveness of Low Vision Rehabilitation in Children Vijaya K. Gothwal; Rebecca Sumalini; Seelam Bharani View Presentation 2772 - B0026. Quantification and evaluation of bivariate contour ellipse area (BCEA) in different diseases after rehabilitation Francesca Verboschi; Vittoria De Rosa; Chiara Di Crescenzo; Gianmarco Rea; Marco Mafrici; Daniela Domanico; Enzo M. Vingolo View Presentation 2773 - B0027. Comparison of Fixation Stability Measured by Laser Scanning Digital Camera and DLP-Cam Benno L. Petrig; Jeff Clendenon; Lisa Ensman; Matthew S. Muller; Ann E. Elsner; Glen Y. Ozawa; Taras V. Litvin; Jorge A. Cuadros; Tuhin Roy; Danny Li View Presentation 2774 - B0028. Do visually impaired participants hear better? An evaluation of self report using a modified version of Speech, Spatial and Qualities of Hearing Scale Shahina Pardhan; Silvia Cirstea; Andrew Kolarik; Brian Moore View Presentation 2775 - B0029. An Object Localization and Feedback System Nii Tete Mante; Gerard Medioni; Armand R. Tanguay; Thang Dinh; Furkan E. Sahin; Patrick J. Nasiatka; James D. Weiland View Presentation 2776 - B0030. Magnification, Field of View and Depth of Field in Low Vision Aids and Optical Instruments Ian L. Bailey View Presentation 2777 - B0031. Preference pattern of low vision aids in glaucoma-redefining guidelines Aparna Rao; Sirajum Monira; Mahasweta Chowdhury View Presentation 2778 - B0032. Sustained benefits of Therapeutic Tinted Contact Lenses (CL) in patients with Albinism Faheemah Saeed; Darrell G. Schlange; Tina Najafi View Presentation 2779 - B0033. Evaluating center of pressure (CoP) measures of postural stability in low and normal vision using the Nintendo Wii Balance BoardTM (WBB) Pamela E. Jeter; Jialiang Gu; Judith E. Goldstein; Ava K. Bittner; Gislin Dagnelie View Presentation 2780 - B0034. Low vision and work opportunities Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 103 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Jørn Kalleberg; Irene Langeggen View Presentation 2781 - B0035. The effect of an Adapted Day Centre on Physical and Psychological WellBeing in Older Adults with Low Vision Walter Wittich; Caitlin Murphy; Daphne Mulrooney View Presentation 2782 - B0036. Vision, Demographic Factors, and Motor Vehicle Collisions in Bioptic Drivers Bradley E. Dougherty; Roanne E. Flom; Mark A. Bullimore; Thomas W. Raasch View Presentation 2783 - B0037. Effects of patient traits on physician-predicted low vision outcomes Tiffany L. Chan; Robert W. Massof; Judith E. Goldstein View Presentation 2784 - B0038. An Inventory of Visually Guided Activities Self-reported by Individuals with Profound Visual Impairment Gislin Dagnelie; Pamela E. Jeter; Lauren Dalvin; Ellen R. Arnold View Presentation 314. Macular Disease other than AMD I Moderator(s): Timothy Olsen (Emory University) and Judy Kim (Medical College of Wisconsin) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 2785 - B0039. Anterior chamber depth in eyes with central serous chorioretinopathy Jong-Hyun Oh; Jaeryung Oh; Yong-Min Choi; Seong-Woo Kim; Kuhl Huh View Presentation 2786 - B0040. Clinical Course of Unoperated Eyes with Vitreofoveal Traction Vishak J. John; Harry W. Flynn; William E. Smiddy; Adam Carver; Robert Leonard; Homayoun Tabandeh; David S. Boyer View Presentation 2787 - B0041. Comparison of A-scan ultrasound and partial coherence laser interferometry: axial length in idiopathic macular hole Jung Yeul Kim; Woo Jin Kim; Ki Yup Nam; Haeng Jin Lee; Yong Il Shin View Presentation 2788 - B0042. Factors that Predict Outcomes of Macular Hole Repair Jack Shao; Lucy T. Xu; Omar S. Punjabi; Justis P. Ehlers; Sunil K. Srivastava; Peter K. Kaiser View Presentation 2789 - B0043. Correlation of pattern electroretinogram and visual acuity in idiopathic epiretinal membrane Ji Eun E. Lee; Hyun Woong Kim; Sung Il Kim; Jong Ho Park; Ik Soo Byon View Presentation 2790 - B0044. Longitudinal Changes in Preferred Retinal Location, Visual Function, Fundus Autofluorescence and Retinal Structure in Stargardt Disease Vivienne C. Greenstein; Mirela R. Tabacaru; Erin Flynn; Rando Allikmets; Stephen H. Tsang View Presentation 2791 - B0045. One-year outcome of two different initial doses of intravitreal ranibizumab for myopic choroidal neovascularization Ya-Hsin Kung; Tsung-Tien Wu View Presentation 2792 - B0046. Morphologic Choroidal Changes in Dome Shaped Macula Combining Indocyanine Green Angiography (ICGA) and Spectral Domain Optical Coherence Tomography (SD-OCT) Francesco Viola; Laura Dell'Arti; Eleonora Benatti; Chiara Mapelli; Giulio Barteselli; Monica Serafini; Roberto Ratiglia View Presentation 2793 - B0047. Quantitative Measurement of Color Discrimination in Cone-Rod Dystrophies and Inherited Maculopathy Brett G. Jeffrey; Wadih M. Zein; Benedetto Falsini; Divya L. Nigam; Paul A. Sieving View Presentation 2794 - B0048. Prevalence of Vitreomacular Interface Disease and Candidates for Ocriplasmin Treatment Lucy T. Xu; Omar S. Punjabi; Jack Shao; Justis P. Ehlers; Sunil K. Srivastava; Peter K. Kaiser View Presentation 2795 - B0049. Clinical evaluation of foveal sparing in patients with Stargardt disease Ramon A. van Huet; Sarah C. Westeneng -van Haaften; Muhamad Muhamad; Frans P. Cremers; Lies H. Hoefsloot; B. Jeroen Klevering; Carel B. Hoyng View Presentation 2796 - B0050. Intravitreal Bevacizumab for Choroidal Neovascularization due to Pathological Myopia: Long-term Outcomes Valentina Sarao; Daniele Veritti; Sara Macor; Paolo Lanzetta View Presentation 2797 - B0051. Comparison of efficacy, safety and costs between half-fluence and halfdose photodynamic therapy for Chronic Central Serous Chorioretinopathy Massimo Nicolo; Chiara M. Eandi; Camilla Alovisi; Carlo E. Traverso View Presentation 2798 - B0052. Visual and Anatomic Results of the Macula Society Photodynamic Therapy (PDT) for Central Serous Chorioretinopathy (CSC) Retrospective Study Jennifer I. Lim; Adam R. Glassman; Lloyd P. Aiello; Usha Chakravarthy; Christina J. Flaxel; Richard F. Spaide View Presentation 2799 - B0053. Foveal Contour after Pars Plana Vitrectomy for Idiopathic Macular Hole Royce W. Chen; Pamela Sherwood; Sri Krishna Mukkamala; Frank S. Siringo; Stanley Chang View Presentation 2800 - B0054. Very early disease manifestations in macular telangiectasia type 2 Tjebo F. Heeren; Frank G. Holz; Peter Charbel Issa View Presentation 2801 - B0055. Familial occurence of chronic central serous chorioretinopathy Myrte B. Breukink; Anneke I. Den Hollander; Jan E. Keunen; Carel B. Hoyng; Camiel J. Boon View Presentation 2802 - B0056. Notching of tissue after macular hole surgery : An abrupt alteration in inner contour of parafoveal tissue associated with foveal tissue elongation Jae Hui Kim; Se Woong Kang; Jaeryung Kim View Presentation 2803 - B0057. Flourescein Fundus Angiography Features of Macular Ischemia in Radiation Retinopathy Senthil Selvam; Dawn A. Sim; Pearse A. Keane; Marcus Fruttiger; Catherine A. Egan; Mandeep S. Sagoo; Adnan Tufail View Presentation 2804 - B0058. Characteristics of Fundus Angiography and Optical Coherence Tomography in Patients with Focal Choroidal Excavation Complicated by Central Serous Chorioretinopathy Mihoko Suzuki; Fumi Gomi; Miki Sawa; Kohji Nishida View Presentation 2805 - B0059. The early visual changes with hydroxychloroquine (HCQ) usage detected with multifocal ERG (mfERG) versus spectral domain OCT (SDOCT) and 10-2 field Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 104 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM testing Anh-Danh T. Phan; Jennifer Eikenberry; Lissa A. McNulty View Presentation 2806 - B0060. Comparison of outcomes between 20, 23 and 25 gauge vitrectomy for idiopathic macular hole Fatma M. Dihowm; Mathew MacCumber View Presentation 2807 - B0061. Evaluation of Retinal Function in Patients with Retinal Toxicity from Hydroxychloroquine after Drug Cessation James Osher; Reshma Katira; Jonathan S. Lyons View Presentation 2808 - B0062. Long-Term Follow-Up Results of Idiopathic Epiretinal Membrane Ik Soo Byon; Kang Yeun Pak; Sung Who Park; Ji Eun E. Lee View Presentation 2809 - B0063. Macular sensitivity and structure in idiopathic epiretinal membranes 12 months after surgical treatment Rodica Isaico; Philippe Koehrer; Frederic Nicot; Alain M. Bron; Catherine P. Garcher View Presentation 2810 - B0064. Length of preoperative ELM and IS/OS line defect correlate with postoperative visual acuity in patients with idiopathic macular hole Manzo Taguchi; Sho Ishikawa; Tadashi Muraoka; Kouzo Harimoto; Tomohito Sato; Masaru Takeuchi View Presentation 2811 - B0065. Intravitreal Ranibizumab for Acute Central Serous Chorioretinopathy SEUNG JUN LEE View Presentation 2812 - B0066. A Comparison of Macular Morphology of Pediatric Versus Adult Eyes with Epiretinal Membranes Adam L. Rothman; Francisco A. Folgar; Amy Y. Tong; Cynthia A. Toth View Presentation 2813 - B0067. Mineralocorticoid Receptor Antagonism in the Treatment of Chronic Central Serous Chorioretinopathy: First Pilot Study Min Zhao; Elodie Bousquet; Francine F. Behar-Cohen View Presentation 2814 - B0068. Fundus autofluorescence at macular hole predicting postoperative visual acuities tasuku yoneda; Manabu Yamamoto; Takeya Kohno; Yusaku Yoshida; Ayako Yasui; Kunihiko Shiraki View Presentation 2815 - B0069. A Comparison of Tests Recommended for Detecting Hydroxychloroquine Related Retinal Toxicity Luz Amaro-Quireza; Evelyn S. Abraham; Stephen H. Tsang; Donald C. Hood; Vivienne C. Greenstein View Presentation 2816 - B0070. Hyperautofluorescent macular ring in a series of enhanced S-cone patients Rony Gelman; Jonathan P. Greenberg; Tobias Duncker; Lawrence A. Yannuzzi; Stephen H. Tsang View Presentation 2817 - B0071. Assessment of the outer and the inner retina using optical coherence tomography and the correlation with visual acuity in idiopathic epiretinal membrane Sung Who Park; Ik Soo Byon; Ji Eun E. Lee View Presentation 2818 - B0072. Systematic use of trypan blue dye in macular pucker surgery: is it worthy? pauline lallemand; Claude Speeg-Schatz; Tristan Bourcier; David Gaucher View Presentation 2819 - B0073. Morphological description of dome-shaped macula in myopic eyes Violaine Caillaux; David Gaucher; Vincent Gualino; Pascale Massin; Ramin Tadayoni; Alain Gaudric View Presentation 2820 - B0074. Retrospective Study of Two or More Dexamethasone Intravitreal Implant 0.7 mg Injections for Retinal Vein Occlusion Antonio Capone; Michael Singer; David G. Dodwell; Richard Dreyer; Kean T. Oh; Daniel B. Roth; John G. Walt; Lanita C. Scott; David A. Hollander View Presentation 2821 - B0075. Refractive errors in high myopic eyes after phacovitrectomy Donghyun Jee View Presentation 2822 - B0076. Macular sensitivity after intravitreal dexamethasone implant (Ozurdex) for retinal vein occlusion Lea Querques; Giuseppe Querques; Rosangela Lattanzio; Maria Lucia Cascavilla; Giacinto Triolo; Edoardo Cavallero; Preziosa Chiara; maria vittoria cicinelli; Francesco Bandello View Presentation 2823 - B0077. Choroidal thickness in retinal vein occlusion: A pilot study Christiana Dinah; Dawn A. Sim; Pearse A. Keane; Adnan Tufail; James S. Talks View Presentation 2824 - B0078. Intravitreal Dexamethasone Implant (Ozurdex) for macular edema secondary to retinal vein occlusion: a comparative study between recent onset and chronic edema Emilia Maggio; Antonio Polito; Antonio Peroglio Deiro; Elisa Benetti; Grazia Pertile View Presentation 2825 - B0079. Early treatment with ranibizumab in severe central retinal vein occlusion Olga Rostaqui; Agnès Glacet-Bernard; Nathalie Massamba; Jennyfer Zerbib; Florence Coscas; Gabriel J. Coscas; Eric H. Souied View Presentation 2826 - B0080. Visual outcomes of intravitreal dexamethasone treatment for retinal vein occlusions in an NHS clinic setting Sonali Nagendran; Narendran Nair; Manju N. Chandran; Geeta Menon View Presentation 2827 - B0081. Visual Acuity Outcomes in Dosing Subgroups of the GALILEO and COPERNICUS study in Patients With Macular Edema Secondary to Central Retinal Vein Occlusion (CRVO) Under PRN Treatment Amelie Pielen; Julia A. Haller View Presentation 2828 - B0082. The long-term effect of intravitreal bevacizumab injection in central serous chorioretinopathy In-Cheon You; Namchon Cho; Dongwook Lee; Min Ahn View Presentation 2829 - B0083. Outer retinal edema as a risk factor for poor visual outcome after bevacizumab therapy for macular edema with branch retinal vein occlusion Daisuke Muramatsu; Maki Mishima; Yoshihiro Wakabayashi; Takuya Iwasaki; Shigemitsu Ishii; Setsuko Kawakami; Keisuke Kimura; Sayaka Gondo; Kazuhiko Umazume; Hiroshi Goto View Presentation 2830 - B0084. Quantitative measurements of autofluorescence in Stargardt’s disease Tobias Duncker; Tomas R. Burke; Jonathan P. Greenberg; Winston Lee; Theodore Smith; Stephen H. Tsang; Janet R. Sparrow; Rando Allikmets; Francois C. Delori View Presentation 2831 - B0085. Case series of Macular Degeneration following Pars Plana Vitrectomy Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 105 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM using Xenon Intraocular Endoillumination Seung Jae Lee; Ju Yong Seok; Haksu Kyung; Soo Young Lee View Presentation 2832 - B0086. Fundus Autofluorescence Patterns in Central Serous Chorioretinopathy Seung-Young Yu; Nam Suk Cho; Eung Suk Kim; young gyun Kim; Hyung-Woo Kwak View Presentation 2833 - B0087. Intravitreal Bevacizumab for the treatment of Central Serous Chorioretinopathy: follow up over 12 months Adam Lewis; Marina Syrimi; Manju N. Chandran; Geeta Menon View Presentation 2834 - B0088. Global Patterns of Fundus Autofluorescence in Stargardt Macular Dystrophy Gad Heilweil; Irena Tsui; Hamid Hosseini; Steven D. Schwartz View Presentation 2835 - B0089. Pairwise Genotype/Phenotype Comparison to Predict Severity of ABCA4 Mutations Crandall E. Peeler; Jillian Huang; Sarwar Zahid; Naheed W. Khan; Kari E. Branham; Kanishka T. Jayasundera; John R. Heckenlively View Presentation 2836 - B0090. A Longitudinal Analysis of 2008-2010 Medicare Claims Data for newly diagnosed macular holes Sunil K. Srivastava; Pravin U. Dugel; Kuo Tong; Andrew J. Layton; Peter K. Kaiser View Presentation 2837 - B0091. Personalized Medicine: Choloroquine Toxicity in human RPE is Dependent on ARMS2 and HTRA1 Genotypes Eric chi-Hsien Peng; Yao Li; Chyuan-Sheng Lin; Stephen H. Tsang View Presentation 2838 - B0092. The REPAIR Study: Prospective, Multi-center Trial of ranibizumab in Choroidal Neovascularization due to Pathological Myopia – the 12 month Primary Endpoint Yit C. Yang View Presentation 2839 - B0093. Assessing Photoreceptor Structure Following Macular Hole Closure Sean Batson; Sean Hansen; Peter A. Karth; Robert F. Cooper; Drew H. Scoles; David V. Weinberg; Alfredo Dubra; Judy E. Kim; Joseph Carroll; William Wirostko View Presentation 315. Retinal Detachment I Moderator(s): Daniel Martin (Cleveland Clinic) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 2840 - B0149. Outcomes of 25-Gauge Vitrectomy with Relaxing Retinectomy for Retinal Detachment with Severe Proliferative Vitreoretinopathy Vikram Setlur; Jennifer I. Lim View Presentation 2841 - B0150. Giant Retinal Tear Associated Retinal Detachment After Pars Plana Vitrectomy: Surgical Techniques and Outcomes Marco A. Gonzalez; Harry W. Flynn; Paul Tenzel View Presentation 2842 - B0151. Symptomatic Posterior Vitreous Detachment: The predictive value of the posterior hyaloid face and symptomatology Christiane I. Falkner-Radler; Minhee Cho; Alexandra Garf; Anton Orlin; R.V. Paul Chan; Szilard Kiss; Donald J. D’Amico; Susanne Binder View Presentation 2843 - B0152. Change in subfoveal choroidal thickness following semental scleral buckling with or without cryotherapy for rhegmatogenous retinal detachment Masayo Kimura; Akira Nishimura; Hideaki Yokogawa; Tetsuhiko Okuda; Tomomi Higashide; Michiharu Shimizu; Kazuhisa Sugiyama View Presentation 2844 - B0153. Intravitreal gas injection without vitrectomy for macular detachment associated with an optic disc pit Hideo Akiyama; Shoji Kishi View Presentation 2845 - B0154. Activation of Rho GTPases after Retinal Detachment Jianfeng Wang; Weiwei Wang; Ellen Townes-Anderson View Presentation 2846 - B0155. Strategy for the Management of Complex Retinal Detachments: The European Vitreo-Retinal Society Retinal Detachment Study Aaron Parnes; Didier Ducournau; Jack O. Sipperley; Ron A. Adelman View Presentation 2847 - B0156. Management and Outcomes of Bilateral Simultaneous Rhegmatogenous Retinal Detachments Mitul Mehta; Robert A. Sisk; Christopher D. Riemann View Presentation 2848 - B0157. The efficacy and safety of prophylactic cryotherapy in preventing retinal detachment in type 1 Stickler syndrome Gregory S. Fincham; Laura Pasea; Christopher Carroll; Annie M. McNinch; Arabella V. Poulson; Allan J. Richards; John D. Scott; Martin P. Snead View Presentation 2849 - B0158. Ranibizumab is a potential prophylaxis for proliferative vitreoretinopathy, a non-angiogenic blinding disease Steven Pennock; David Kim; Shizuo Mukai; Matthew Kuhnle; Dal Chun; Joanne A. Matsubara; Jing Z. Cui; Patrick e. Ma; David Maberley; Andrius Kazlauskas View Presentation 2850 - B0159. The usefulness of internal limiting membrane peeling to prevent macular pucker formation for regmatogenous retinal detachment without foveal detachment Masanori Miyazaki; Tatsuro Ishibashi View Presentation 2851 - B0160. Membrane-bound Fas ligand has a critical role in photoreceptor cell death in an experimental model of retinal detachment Hidetaka Matsumoto; Yusuke Murakami; Dimosthenis Mantopoulos; George Trichonas; Joan W. Miller; Meredith S. Gregory-Ksander; Bruce R. Ksander; Demetrios Vavvas View Presentation 2852 - B0161. Effects of low-dose isotretinoin on rates of recurrent retinal detachment secondary to proliferative vitreoretinopathy Francis C. DeCroos; Michael Dollin; Nikolas J. London; Lisa Maiale; Philip P. Storey; Jason Hsu; James Vander; Carl D. Regillo View Presentation 2853 - B0162. Complete prevention of retinal detachment using prophylactic intraoperative septated circumferential barrier laser during macular surgery: long-term follow-up results June-Gone Kim; Hyun Seung Yang View Presentation 2854 - B0163. Involvement of Autophagy in z-VAD-FMK Induced Photoreceptor Necroptosis, a Caspase-Independent Cell Death, after Experimental Retinal Detachment Kai Dong; Xiaodong Sun; Genjie Ke View Presentation 2855 - B0164. Intraocular pressure abnormalities following silicone oil injection for complicated retinal detachments Hiroaki Ozaki; Jane Y. Huang; Eiichi Uchio Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 106 sur 222 View Presentation 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 2856 - B0165. Risk of intraoperative retinal tears and recurrent rhegmatogenous retinal detachment in eyes with previous retinal detachment undergoing pars plana vitrectomy Ravi S. Singh; Douglas J. Covert; Dennis P. Han View Presentation 2857 - B0166. A Model of Tractional Retinal Detachment in the Rabbit Eye Walid F. Abdallah; Ernesto Barron; Gerald J. Chader; Mark S. Humayun View Presentation 2858 - B0167. Intraocular fluid levels of immune mediators in retinal detachment Shunichiro Ueda; Yoshihiko Usui; Yoko Okunuki; Takeshi Kezuka; Yoshihiro Wakabayashi; Hiroshi Goto View Presentation 2859 - B0168. The Utility Of Scleral Depression For Detecting Peripheral Vitreoretinal Pathology Nikhil N. Batra; Ravi D. Patel; Shaun Ittiara; Seenu M. Hariprasad View Presentation 2860 - B0169. Endolaser Associated with Cystoid Macular Edema (CME) and Epiretinal Membrane (ERM) Formation Following Small Gauge Retinal Detachment (RD) Repair Tanuj Banker; Gayatri Reilly; Eric Weichel; Kyle Godfrey View Presentation 2861 - B0170. Recovery of visual function in macula-off rhegmatogenous retinal detachment Mathijs v. Put; Danna Croonen; Ilja M. Nolte; Johanna M. Hooymans; Leonoor I. Los View Presentation 2862 - B0171. Visual loss in retinal detachment and macula-on after successful surgery, Retina 1 project Jose-Carlos Pastor; Itziar Fernandez; Melissa Castrejon; Jimena Rojas Spano; Rosa Coco; MRosa Sanabria; Enrique Rodriguez de la Rua View Presentation 2863 - B0172. Retinal blood velocity in rhegmatogenous retinal detachment recovered after vitrectomy but did not change after scleral buckling procedure AYANO KAJIYAMA; Kiyoshi Suzuma; Hirofumi Kinoshita; Ryotaro Ueki; Takashi Kitaoka View Presentation 2864 - B0173. Giant Retinal Tear Detachments: Surgical Strategies and Outcomes John D. Pitcher; Mohammed A. Khan; Philip P. Storey; Michael Dollin; Carl D. Regillo; Sunir J. Garg View Presentation 2865 - B0174. Corneal Sensitivity and Pupil Motility in Patients with Retinal Detachment Treated with Vitrectomy and Circumferential Laser Photocoagulation: Comparison Between 810 nm Diode and 523 nm Argon Lasers Alexis Pinel; Lucie Biard; Vincent Pierre-Kahn View Presentation 2866 - B0175. Retinal redetachment and post-operative days of hospitalization Maria L. Livani; Stefano Valente; Erika Rigoni; Vittoria De Rosa; Gianmarco Rea; Enzo M. Vingolo View Presentation 2867 - B0176. Use of Retained Perfluoron as a Temporary Vitreous Substitute for Inferior Rhegmatogenous Retinal Detachments Gregory Richard; Benjamin Guidry; Ching J. Chen; Heather Hancock View Presentation 2868 - B0177. Vitrectomy with anterior drainage without perfluorocarbon liquid for retinal detachment repair Christopher Rosicki; Cindy S. Hwang; Jaafar El Annan; Annal D. Meleth; Petros Carvounis View Presentation 2869 - B0178. Assessing Macular Morphology with Spectral Domain-Optical Coherence Tomography Following Rhegmatogenous Retinal Detachment Repair Hemang K. Pandya; Asheesh Tewari; Gary W. Abrams View Presentation 2870 - B0179. Scleral buckling versus primary vitrectomy in patients with rhegmatogenous retinal detachment at high risk for proliferative vitreoretinopathy Rayan Alshareef; Mohammed Khuthaila; Philip P. Storey; Richard S. Kaiser; Benjamin Leiby; Nikolas J. London; Natalie Fang-Yen View Presentation 2871 - B0180. Inhibition of autophagy by 3MA enhances the effect of ERS-mediated apoptosis in photoreceptors after experimental retinal detachment Hong Zhu; Fenghua Wang; Xiaodong Sun View Presentation 2872 - B0181. Morphologic changes after retinal detachment surgery using spectral domain optical coherence tomography SOLDERMANN yoann; Boujnah Ygal; Cornut Pierre Loic; Beccat Sylvain; Burillon Carole View Presentation 2873 - B0182. VITREORETINAL SURGERY WITH SILICONE OIL INJECTION IN UNCOMPLICATED RHEGMATOGENOUS RETINAL DETACHMENT: CLINICAL AND INTRA-OCLUAR PRESSURE OUTCOMES George Azar; Elyse Jabbour; Joelle Antoun; Alexandre Jalkh View Presentation 2874 - B0183. Incidence of tears and retinal detachments after macular surgery according to the depression of the vitrectomy cutter Jérôme Selton; Isabelle Hubert; Jean Paul Berrod View Presentation 2875 - B0184. Small gauge direct silicon oil (SO) perfluoro-n-octane (PFO) interchange. Comparison of two methods: use of chandelier light (CHL) and use of viscous fluid infusion cannula(VFIC) Hugo Quiroz-Mercado; Ramanath Bhandari; Shulamit Schwartz; Jeffrey Olson; Scott Oliver; Naresh Mandava; Raul Velez-Montoya; Marc Mathias View Presentation 2876 - B0185. Minimal invasive scleral buckling surgery without limbal peritomy for uncomplicated primary rhegmatogenous retinal detachment Peiquan Zhao; Haiying Jin; Qi Zhang View Presentation 2877 - B0186. Same day versus next day repair of fovea threatening primary rhegmatogenous retinal detachments Ian Gorovoy; Travis Porco; Jay M. Stewart View Presentation 2878 - B0187. Relationship between axial length and retinal tear location in the rhegmatogenous retinal detachment surgery Young Ju Lew; Ji Sun Baek; Yu Mi Kim; Jung Il Han; Eun Jee Chung; Tae Gon Lee View Presentation 316. Clinical and Translational Studies in Ocular Infection and Immunity Moderator(s): Mary Marquart (Univ of Mississippi Med Ctr) and Manabu Mochizuki (Tokyo Med Dental Univ Grad Sch) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM View Session Details 2879 - B0248. A High Speed Detection Platform Based on Surface-Enhanced Raman Scattering for Rapid Diagnosis of Bacterial Endophthalmitis Ching-Ju Hsieh; Fung-Rong Hu; Da-Wei Wang; Juen-Kai Wang; Yuh-Lin Wang; ChiHung Lin Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 107 sur 222 View Presentation 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 2880 - B0249. Longitudinal Cytokine Analysis of Aqueous Humor in CMV Retinitis - The CMV Retinitis Intravitreal Ganciclovir Singapore Study (CRIGSS) Jayant V. Iyer; Bijin Au; Suisheng Tang; John E. Connolly; Rupesh V. Agrawal; Tun Kuan Yeo; Stephen C. Teoh View Presentation 2881 - B0250. SPECTRAL DOMAIN-OPTICAL COHERENCE TOMOGRAPHY FINDINGS IN ACUTE SYPHILITIC POSTERIOR PLACOID CHORIORETINOPATHY Antonio P. Ciardella; Francesco Pichi; Emmett T. Cunningham; J. Michael Jumper; Janet L. Davis; Thomas A. Albini; David Sarraf; Enrico Bertelli; Mariachiara Morara; Paolo Nucci View Presentation 2882 - B0251. Ocular syphilis: case series (2000-2009) from two tertiary care centers in Montreal Kinda Najem; Laurence Jaworski; Annie-Claude Labbé; Claude Fortin; Éric Fortin; MarieLyne Bélair; Bouchra Serhir; Marie-Josée Aubin View Presentation 2883 - B0252. Utility of Lyme Antibody Testing in the Uveitis Workup Lana M. Rifkin; Andrea D. Birnbaum; Anjali S. Parekh; Chaisiri Jumroendararasame; Dmitry Pyatetsky; Debra A. Goldstein View Presentation 2884 - B0253. A Comparison of the Etiology of Infectious Corneal Ulcers and Bacterial Susceptibility to Antibiotics in Non-Contact Lens and Contact Lens Wearers at the University of Chicago Krishna Patel; Michael A. Saidel View Presentation 2885 - B0254. Association of Type III Secretion System, Serotype, and Antibiotic Susceptibility of P. aeruginosa from Ocular Isolates Elizabeth Shen; Fung-Rong Hu View Presentation 2886 - B0255. Prevalence and characteristics of MRSA from clinical conjunctivitis trials versus ocular surveillance studies Timothy W. Morris; Christine M. Sanfilippo; Christine K. Hesje; Matthew E. MacGilvray; Wolfgang Haas View Presentation 2887 - B0256. Detection of Organisms by Microbiology vs. Histopathology in Corneal Biopsy and Penetrating Keratoplasty Specimens Sander R. Dubovy; Nancy Buchser; Guillermo Amescua; Darlene Miller View Presentation 2888 - B0257. The Effects of Using Steroid or Combination Antibiotic/Steroid Drops on Ocular Culture Results Peter Belin; Darlene Miller; Ajay E. Kuriyan; Harry W. Flynn View Presentation 2889 - B0258. Interleukin-6 Gene Polymorphisms in Patients with Keratitis venkata nagaraju konda; Mark D. Willcox; Inderjeet Kaur; Preeji M. Sudharaman; Prashant Garg; Subhabrata Chakrabarti View Presentation 2890 - B0259. Demographics and Bacterial Contamination Influences in Antibacterial Effectiveness of Human Milk Justin Baynham; Allison Moorman; Catherine Donnellan; Vicky Cevallos; Jeremy D. Keenan View Presentation 2891 - B0260. Keratitis-induced changes to the homeostatic microbiome at the human cornea Alexander I. Tuzhikov; Qunfeng Dong; Alexander Y. Panchin; Onsiri Thanathanee; Nabeel M. Shalabi; David Nelson; Lakshmi Akileswaran; Russell N. Van Gelder; Terrence P. O'Brien; Valery I. Shestopalov View Presentation 2892 - B0261. Stratification of antigen-presenting cells within the normal human cornea Jared E. Knickelbein; Kristine-Ann Buela; Robert L. Hendricks View Presentation 2893 - B0262. Human tear fluid triggers virulence expression by Pseudomonas aeruginosa biofilms growing on soft contact lenses Yvonne Wu; Connie Tam; David J. Evans; Suzanne M. Fleiszig View Presentation 2894 - B0263. Efficacy of photodynamic antimicrobial chemotherapy on gram negative bacteria Taiichiro Chikama; Miftahul Akhyar Latief; Momoko N. Shibasaki; Ji-Ae Ko; Takaaki Sasaki; Yoshiaki Kiuchi; Takemasa Sakaguchi; Akira Obana View Presentation 2895 - B0264. Increasing coverage of a vaccine against herpes zoster at New York University Langone Medical Center and Bellevue Hospital Ilyse D. Haberman; Elisabeth J. Cohen; Zachary Elkin; Judith D. Goldberg; Xiaochun Li; Eliana Castano; Lisa Park; Michael H. Perskin View Presentation 2896 - B0265. Rare and newer Non Sporulating Moulds emerging as corneal pathogens identified by molecular techniques in a Tertiary Eye Care Centre Gayathri Ramasubban; Lily Therese; Bagyalakshmi Radhakrishnan; Hajib N. Madhavan View Presentation 2897 - B0266. Efficacy and Safety of Voriconazole and Amphotericin B as Additives in Optisol-GS Corneal Storage Media Against Candida Species Noelle Layer; Vicky Cevallos; Andrew J. Maxwell; Caroline Ulrickson; Jeremy D. Keenan; Bennie H. Jeng View Presentation 2898 - B0267. Rapid and sensitive diagnosis of Acanthamoeba keratitis by loopmediated isothermal amplification Ge Zhao; Qing Yuan View Presentation 2899 - B0268. Topical Linezolid 0.2% for the Treatment of Gram Positive Bacterial Keratitis Elmer Y. Tu; Sandeep Jain View Presentation 2900 - B0269. Predictors of outcome in fungal keratitis using data from the Mycotic Ulcer Treatment Trial I Catherine Q. Sun; Namperumalsamy V. Prajna; Tiruvengada Krishnan; Muthiah Srinivasan; Kathryn J. Ray; Stephen D. McLeod; Travis Porco; Nisha Acharya; Thomas M. Lietman View Presentation 2901 - B0270. Acanthamoeba Keratitis – a clinical outcome Mark Saeger; Anne Saeger; Konstantine Purtskhvanidze; Stefan O. Koinzer; Johann Roider; Bernhard Noelle View Presentation 2902 - B0271. Microstructural analysis of radial keratoneruitis in patients with early stage Acanthamoeba keratitis using in vivo confocal microscopy Natsuko Yamazaki; Akira Kobayashi; Hideaki Yokogawa; Kazuhisa Sugiyama View Presentation 2903 - B0272. Antibiotic resistance and molecular characterization of ocular isolates of Acinetobacter baumanniii Deepa Talreja; Chithra Muraleedharan; Keith Kaye; Satish K. Walia; Ashok Kumar View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 108 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 2904 - B0273. Antibiotic Resistance Surveillance of Ocular Pathogens - four years of ARMOR Study Results Wolfgang Haas; Jennifer Deane; Timothy W. Morris; Daniel F. Sahm View Presentation 2905 - B0274. Case Control Study of Herpes Zoster Ophthalmicus in the Bronx Using Population-based and Clinic-based Controls David M. Poulsen; Grace Honik; David C. Gritz View Presentation 2906 - B0275. Clinical and Microbiological profile of Paediatric Keratitis in a tertiary care hospital in Hong Kong Vishal Jhanji; Alvin L. Young; K. S. Leung; Nicole Tsim; Mamie Hui; Lulu Cheng View Presentation 2907 - B0276. Assessment of Risk Factors for Oxacillin-Resistant Ocular Flora from Patients Undergoing Cataract Surgery Hugo Y. Hsu; John T. Lind; Darlene Miller View Presentation 2908 - B0277. Clinical and Pathologic Findings in Patients with Suspected Infectious Keratitis: A Single Institution Experience Yousef J. Cruz-Inigo; Sanjay V. Patel; Leo Maguire; Joaquin J. Garcia ; Diva R. Salomao View Presentation 2909 - B0278. Clinical features of anterior uveitis caused by three different types of herpes virus Jun Suzuki; Junichi Sakai; Yoshihiko Usui; Takeshi Kezuka; Hiroshi Goto View Presentation 2910 - B0279. Comparative efficacy of two different regimens of povidone-iodine 5% eye drops instillation in reducing conjunctival bacterial flora – a preliminary report Leticia F. Barroso; Antonio Brunno Nepomuceno; Sarah P. Cazella; Jefferson A. Ribeiro; Liliane Castilho; Andre Messias; Rodrigo Jorge View Presentation 2911 - B0280. Ocular straylight and contrast sensitivity in HIV-positive patients compared with normal subjects Nazli Demirkaya; Thomas J. Van Den Berg; Stanley Darma; Reinier O. Schlingemann; Frank D. Verbraak View Presentation 2912 - B0281. Ocular manifestations of Granulomatosis with Polyangiitis from the “Institute of Ophthalmology Conde de Valenciana” Miguel Pedroza-Seres; Edson J. Robles; Diana A. González View Presentation 2913 - B0282. Molecular Quantification of Herpes Simplex Virus (HSV) by Real-Time PCR in Tear Film and Correlation with Human Disease Nora L. Cothran; Kacy Ramirez; Rebecca Thompson; Anami Patel; Daniel G. Fuller; John DeVincenzo View Presentation 2914 - B0283. Effective treatment of Herpes Zoster Ophthalmicus Acute with a single injection preauricular Eduardo Arenas; Fernando Alvizu View Presentation 2915 - B0284. Yield of Ophthalmology Consults in Fungemic Patients in a Tertiary Care Hospital Setting Ankoor R. Shah; Devon Ghodasra; Brian VanderBeek View Presentation 2916 - B0285. Interferon Alpha in the Treatment of Chronic Cystoid Macular Edema Following Cataract Surgery (Irvine-Gass Syndrome) Christoph M. Deuter; Faik Gelisken; Manfred Zierhut; Deshka Doycheva View Presentation 2917 - B0286. Monitoring necrotizing viral retinitis by gene amplification of ocular fluids Anne Sikorav; Phuc Le Hoang; Flore Rozenberg; Bahram Bodaghi View Presentation 2918 - B0287. Yellowish dots in the retina: a new finding of ocular syphilis? Renan Rodrigues; Gustavo Salomao; Heloisa Nascimento; Cristina Muccioli View Presentation 2919 - B0288. Demographics and Clinical Characteristics of Patients Presenting with Ocular Manifestations of Systemic Syphilis Archana T. Seethala; Nicole H. Siegel; Steven D. Ness; Deeba Husain View Presentation 2920 - B0289. THe Efficacy and Outcomes of combination Intravitreal Foscarnet and Ganciclovir in Herpetic Retinitis Rajiv E. Shah; Sunir J. Garg View Presentation 2921 - B0290. Novel Minimum Inhibitory Concentration (MIC) Assay to Measure the Effectiveness of Antimicrobial Treatments Against Acanthamoeba Trophozoites and Cysts Christopher Kovacs; Shawn C. Lynch; Joseph G. Carr; Christine M. Sanfilippo; Wolfgang Haas; Jenilee Kilbury; Kimberly A. Millard; Timothy W. Morris View Presentation 2922 - B0291. Phylogenetic study of Acanthamoeba genotypes determined by 18S rDNA gene analysis Denise Freitas; Felipe Marques de Carvalho Taguchi; Linda C. Carrijo-Carvalho; Viviane Peracini; Annette Foronda; Fábio Ramos View Presentation 2923 - B0292. The Preventive Effect by the Drug Released Soft Contact Lens against Bacterial Endophthalmitis Shinichiro Kobayakawa; Toru Matsunaga View Presentation 2924 - B0293. Culture and Reverse Transcriptase Polymerase Chain Reaction (RTPCR) proven Tuberculous Endophthalmitis – First report from a Tertiary Eye Centre Ekta Rishi; Lily Therese; Vishal R. Sharma; Ramasubban Gayathri; Lakshmipathy Dhanurekha; Pukhraj Rishi; Hajib N. Madhavan View Presentation 2925 - B0294. Rate of endophthalmitis following elective cataract surgery Amos Aranowicz; Karsten U. Kortuem; Martin M. Nentwich; Yazmin Yactayo Miranda; Anselm Kampik; Herminia Mino de Kaspar View Presentation 2926 - B0295. Prevalence of Staphylococcal Cassette Chromosome Mec (SCCmec Cassette) Types and Panton-Valentine Leukocidin (PVL) Toxin Among Staphylococcus aureus Vitreus and Anterior Chamber Isolates Noy Ashkenazy; Jorge Maestre; Ashkan M. Abbey; Darlene Miller; Harry W. Flynn View Presentation 317. Posterior Segment Inflammation I Moderator(s): Masaru Takeuchi (National Defense Medical College) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 2927 - B0296. Evaluation of Suprachoroidal Microinjection of Triamcinolone Acetonide in a Model of Panuveitis in Albino Rabbits Samirkumar R. Patel; Ricardo Carvalho; Karen E. Mundwiler; Carol Meschter; Rozemarijn S. Verhoeven View Presentation 2928 - B0297. Beta-glucogallin Suppresses Lipopolysaccharide-induced Inflammatory Markers by Aldose Reductase Inhibition in Murine Macrophages and Ocular Tissues Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 109 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM KUN-CHE CHANG; Brian Laffin; Jessica Ponder; Anna Enzsoly; Janos Nemeth; Daniel V. LaBarbera; Jonathan M. Petrash View Presentation 2929 - B0298. Investigation of the role of CD70 in the development of experimental autoimmune uveitis in mice Yoko Okunuki; Yoshihiko Usui; Ryusaku Matsuda; Fumitaka Kamachi; Akihiko Umazume; Shunichiro Ueda; Takeshi Kezuka; Hisaya Akiba; Hiroshi Goto View Presentation 2930 - B0299. Angiotensin-Converting Enzyme 2 (ACE2) Activator DIZE Ameliorates Endotoxin-Induced Uveitis in Mice Yiguo Qiu; Pollob K. Shil; Ping Zhu; Hongxia Yang; Bo Lei; Qiuhong Li View Presentation 2931 - B0300. Adulthood Uveitis Epidemiology at a Single Spanish Tertiary Referral Centre Victor Llorens; Marina Mesquida; Laura Pelegrin; Blanca Molins; Alfredo Adan Civera View Presentation 2932 - B0301. A national survey of Canadian ophthalmologists’ knowledge and application of uveitis management guidelines Crystal Cheung; Nima Noordeh; Chloe Gottlieb View Presentation 2933 - B0302. Intravitreal dexamethasone implant for the treatment of persistent Uveitic Macular Edema Alfredo Adan Civera; Victor Llorens; Marina Mesquida; Blanca Molins; Ana Isabel de Rocha Cardoso ; Mariana R. Santos de Almeida; Laura Pelegrin View Presentation 2934 - B0303. Long-term results of fluocinolone acetonide intravitreal implant in Behcet's patients with intractable posterior uveitis Eun kyu Oh; Hyeong Gon Yu View Presentation 2935 - B0304. Long-term results of Intravitreal Bevacizumab for the Treatment of Choroidal Neovascular Membranes associated with Presumed Ocular Histoplasmosis Syndrome Sarah Escott; Susie Chang; Ahmad Tarabishy; Mark Barsamian; John B. Christoforidis; Frederick Davidorf; Alan Letson View Presentation 2936 - B0305. Trimethoprim-sulfamethoxazole versus placebo to reduce the risk of recurrences of Toxoplasma gondii retinochoroiditis: randomized controlled clinical trial (ISROT) Joao P. Felix; Rafael S. Zacchia; Jaqueline M. Toribio; Mauricio A. Nascimento; Carlos E. Arieta; Heitor Panetta; Valdir Balarin; Rodrigo P. Lira View Presentation 2937 - B0306. The Effect of Subsets of Monocytes on T cell activation and its implication in uveitis Zhiyu Li; Baoying Liu; Megan Casady; Jennifer Dailey; Sima Hirani; Shayma Jawad; Robert Katamay; H Nida Sen; Robert B. Nussenblatt View Presentation 2938 - B0307. Efficacy and safety of systemic infliximab for uveitis in Behçet's disease aya tobe; Toshiyuki Oshitari; Shuichi Yamamoto View Presentation 2939 - B0308. The Prevalence, Incidence and Risk Factors for Exudative Retinal Detachment in Uveitis Deepika Shah; Craig Newcomb; Grace Levy-Clarke; Robert B. Nussenblatt; James T. Rosenbaum; Eric B. Suhler; Jennifer E. Thorne; C. Stephen Foster; Douglas A. Jabs; John H. Kempen View Presentation 2940 - B0309. Imaging of paravascular infiltrates and epiretinal proliferation in posterior uveitis using adaptive optics Michel Paques; Marie-Hélène Errera View Presentation 2941 - B0310. OCT characteristics of patients with uveitis with epiretinal membranes, cystoid macular edema, or both Ghazala A. Datoo O'Keefe; Hossein Nazari Khanamiri; Narsing A. Rao View Presentation 2942 - B0311. Association between choroidal thickness and activity of ocular inflammation in Behçet's disease Sho Ishikawa; Manzo Taguchi; Tadashi Muraoka; Masaru Takeuchi View Presentation 2943 - B0312. Microperimetric Assessment of Macular Changes in Vogt-KoyanagiHarada Disease Xiu-Ling Tan; Stephen C. Teoh; Su Ling Ho View Presentation 2944 - B0313. DEMOGRAPHICS AND CLINICAL FEATURES IN SERPIGINOUS CHOROIDOPATHY AND ACUTE MULTIFOCAL PLACOID PIGMENTED EPITHELIOPATHY (AMPPE) Ester Carreno; Dawn A. Sim; Pearse A. Keane; Javier Zarranz-Ventura; Guillermo Fernandez Sanz; Dhanes Thomas; Mark C. Westcott; Adnan Tufail; Carlos E. Pavesio View Presentation 2945 - B0314. Masquerade Syndromes Amr Kouchouk; Monica D. Dalal; H Nida Sen; Robert B. Nussenblatt; Landon Grange; Mahdi Rostamizadeh View Presentation 2946 - B0315. Spontaneous Dislocation of the Pellet from the Strut in the Fluocinolone Acetonide Sustained Release Implant (Retisert®) Sujit Itty; Joseph Martel; Glenn J. Jaffe View Presentation 2947 - B0316. Effect of Treatment Modality on Quality of Life in Patients with NonInfectious Uveitis Wei Gui; Matthew Dombrow; Inna Marcus; Baylah Tessier-Sherman; Meredith H. Stowe; John Huang View Presentation 2948 - B0317. Detection of Progression of Visual Field Loss in Serial Humphrey Visual Fields in Birdshot Chorioretinopathy by Pointwise Linear Regression Analysis Bharti Arya; Mark C. Westcott; Carlos E. Pavesio View Presentation 318. Cataractogenesis Moderator(s): J Zigler (Johns Hopkins Univ/Wilmer Eye Inst) and Paul FitzGerald (Univ of California, Davis) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 2949 - C0040. Posterior capsular plaques express cell junction proteins implying their epithelial origin and involvement of MAPK/ERK pathway in modulating cell junction proteins Anshul I. Arora; Alpesh R. Patel; Kaid Johar; Darshini A. Ganatra; Forum B. Kayastha; Devarshi U. Gajjar; Abhay R. Vasavada View Presentation 2950 - C0041. EGFR-Blockade With Erlotinib Influences FGF, EGF, TGF-β2 And EGFR Expression and causes Changes In Actin-Cytoskeleton which might influence Different Aspects Of Cellular Migration In A Time Lapse Microscopy Analysis of Human Lens Epithelial Cells Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 110 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Christian M. Wertheimer; Raffael Liegl; Marcus Kernt; Denitsa Docheva; Anselm Kampik; Kirsten Eibl-Lindner View Presentation 2951 - C0042. Co-culture with material-activated macrophages induce an inflammatory phenotype in lens epithelial cells Rob Pintwala; Cameron K. Postnikoff; Maud Gorbet View Presentation 2952 - C0043. Ultrastructural Changes in Regenerated Tissue Around a Polyvinylpyrrolidone Hydrogel Accommodative Intraocular Lens during Long-term Observation Kyoko Miura; Yuko Shinohara; Satoshi Yokota; Shinji Nagasaka; Masayoshi Nakatani; Tsutomu Sunada View Presentation 2953 - C0044. Histone Deacetylase Inhibitors Trichostatin A and Vorinostat Inhibit TGFβ2 –Induced Epithelial to Mesenchymal Cell Transition of Lens Epithelium K Krishna Sharma; Leike Xie; Puttur Santhoshkumar; Lixing W. Reneker View Presentation 2954 - C0045. An In Vitro Pseudozonule Model of Posterior Capsular Opacification: Effects of Anti-Vascular Endothelial Growth Factor-A Humanized Monoclonal Antibody (Bevacizumab®) on Epithelial-to-Mesenchymal Transition in Lens Epithelium Jong Hwa Jun; Rebecca Kim View Presentation 2955 - C0046. The Effect of Sulfasalazine - Hyaluronic Acid Complex on Posterior Capsule Opacification Choun-Ki Joo; Jun-Sub Choi View Presentation 2956 - C0047. EGF-Receptor inhibitor Gefitinib as a potential pharmacological prophylaxis for posterior capsule opacification Peter Laubichler; Christian M. Wertheimer; Raffael Liegl; Marcus Kernt; Armin Wolf; Christos Haritoglou; Anselm Kampik; Kirsten Eibl-Lindner View Presentation 2957 - C0048. Smad3 and MRTF regulation of TGFβ−induced EMT in mouse lens explants Scott A. Bowman; Anna Korol; Madhuja Gupta; Judith A. West-Mays View Presentation 2958 - C0049. Role of Rho-ROCK signaling in TGFβ-mediated MRTF-A localization during EMT of LECs Anna Korol; Judith A. West-Mays View Presentation 2959 - C0050. Association of ocular ultraviolet radiation exposure with the progression of cataract in South Indian population Rashima Asokan; Ronnie J. George; Vijaya Lingam View Presentation 2960 - C0051. Identification of Peptides of αA- and αB-Crystallins that are Present in Cataractous Human Lenses but Not in Age-Matched Normal Lenses Om P. Srivastava; Kiran Srivastava; Ekta Tiwary View Presentation 2961 - C0052. Evaluation of the topographical characteristics and elasticity of human anterior lens capsule in cataract patients using atomic force microscopy Alpesh R. Patel; Anshul I. Arora; Darshini A. Ganatra; Forum B. Kayastha; Rajkumar Sankaranarayanan; Devarshi U. Gajjar; Abhay R. Vasavada View Presentation 2962 - C0053. Adult zebrafish with cataracts show reduced OKR and altered color perception Heather Prior; Rachel Tuininga; Kerri Letwin; Amber Tuininga View Presentation 2963 - C0054. Protective Effect of Caffeine Against High Sugar Induced Transcription of Micro-RNAs and Consequent Gene Silencing. A Study Using Galactosemic Mice Lenses Shambhu D. Varma; Svitlana Kovtun View Presentation 2964 - C0055. Regulation of Sumoylation in Lens Epithelial Cells During Aging And Oxidative Stress: Sumoylation Reduces LEDGF’s Stability And DNA-Binding Efficiency Bhavana Chhunchha; Nigar Fatma; Eri Kubo; Dhirendra P. Singh View Presentation 2965 - C0056. Hydrogen saline may prevent selenite-induced cataract in rats Hong Yan; Chun-xiao Yang View Presentation 2966 - C0057. Role of apoptosis in the development of senile cataract Claudia Palacio; Marilu Arredondo; Oscar Guerrero-Berger; Laura Leticia Arroyo-Muñoz; Atzin Robles-Contreras View Presentation 2967 - C0058. A Potential Molecular Mechanism of Cataract Development in CRYAAN101D Transgenic Mice Compared to CRYAAWT Mice Shylaja M. Hegde; Kiran Srivastava; Roy Joseph; Om P. Srivastava View Presentation 2968 - C0059. Characterization of Periaxin in the lens and cataract formation Deepika Arora; Chun-hong Xia; Jing Zeng; Zoey Huang; Mei Li; Xiaohua Gong View Presentation 2969 - C0060. Ontario Ginseng Extracts Protect Against Cataract And Oxidative Stress In Pig Lenses Exposed To High Energy Proton And Neutron Irradiation Tomasz M. Dzialoszynski; Earl Noble; Guangyu Li; John R. Trevithick View Presentation 2970 - C0061. A Variant in the SLC35D1 gene is associated with Age-Related Cataract in India Periasamy Sundaresan; Ravilla D. Ravidran; Praveen Vashist; Saravanan Vijayan; Dorothea Nitsch; Giovanni Maraini; Monica Camparini; Chakravarthy Usha; James F. Hejtmancik; Astrid E. Fletcher View Presentation 2971 - C0062. Thermally induced cataract is modulated by the biology of the lens Zhaohua Yu; Nooshin TalebiZadeh; Martin Kronschlager; Per G. Söderberg View Presentation 2972 - C0063. A Targeted Proteomics Approach Using Stable Isotope labeling To Measure Sulfhydryl Oxidation In Human Lens Crystallins Larry L. David; Eileen E. Yue; Phillip A. Wilmarth View Presentation 2973 - C0064. Human apoptotic proteome of senile cataract Atzin Robles-Contreras; Claudia Palacio; Marilu Arredondo-Flores; Jacqueline L. OlivaRamirez; Hector J. Perez-Cano View Presentation 2974 - C0065. Non-Homologous End Joining Repair in the Lens Andrew J. Smith; Kamal Manzar; Meghan Betts; Richard P. Bowater; John R. Reddan; Michael Wormstone View Presentation 2975 - C0066. The effect of total lens epithelial cell eradication on intraocular lens stability in the human capsular bag Julie A. Eldred; Sarah L. Russell; Richard P. Evans-Gowing; Michael Wormstone; David Spalton View Presentation 2976 - C0067. Expression of oxidative markers in laser treated rat lenses Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 111 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Thomas Holm; Leif Johnson; Line Kessel View Presentation 2977 - C0068. Alpha-tocopherol protection against UVR induced cataract, estimation of confidence interval for MTD-2.3:16 and comparison of MTD-2.3:16 estimates Per G. Soderberg; Konstantin Galichanin; Martin Kronschlager; Zhaohua Yu; Nooshin TalebiZadeh View Presentation 2978 - C0069. Cysteine delivery to the lens: a strategy for delaying nuclear cataract? Julie C. Lim; Leo Lam; Lincoln A. Peung; Bo Li; Paul J. Donaldson View Presentation 2979 - C0070. Effects of Various Antioxidants on Lens Epithelial Cells In Vitro and Ex Vivo Eric J. Miller; Anne J. Gemensky-Metzler; David A. Wilkie; Carmen M. Colitz; Heather L. Chandler View Presentation 2980 - C0071. The gender-different effects of antioxidant supplement containing lutein on the expression of aquaporin 8 in the lenticular anterior capsule among cataract patients Rijo Hayashi; Shimmin Hayashi; Kiyomi Arai; Miki Sakai; Makoto Chikuda View Presentation 2981 - C0072. Genistein in various dietary forms does not alter C-terminal truncation of alphaA-crystallin in cataracts in ICR/f rats Stephen Barnes; Kyle A. Floyd; Landon Wilson; David M. Anderson; Kevin L. Schey View Presentation 2982 - C0073. Conditional Expression of hSVCT2 using αA-Crystallin Promoter with Pax6 Consensus Binding Sites for Long-term Studies of Crystallin Ascorbylation and Cataractogenesis in Mouse Vincent M. Monnier; Michael L. Robinson; Christopher Strauch; Xingjun Fan View Presentation 319. Cataract Surgery III Moderator(s): Frank Lovicu (University of Sydney) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 2983 - C0074. Initial Results and Patient Satisfaction After ReSTOR Multifocal TORIC Intraocular Lens Implantation Maan alkharashi; Marino Discepola View Presentation 2984 - C0075. Comparison of Refractive Outcomes Following Phacoemulsification with Intraocular Lens Implantation in Glaucoma, Glaucoma Suspect, and Non-Glaucomatous Patients Greg Bever; Natalie Morgenstern; Babak Eliassi-Rad View Presentation 2985 - C0076. Intracameral moxifloxacin for prophylaxis of endophthalmitis after cataract surgery: A case Series leonardo ferlini; Luciano Perrone; Gaston Gomez Caride; Mike M. Manotas ; Walter Biagini; Ivan Saul; gerardo valvecchia View Presentation 2986 - C0077. Biometrical Measurements for the Anterior Segment Dimensions of the Eye with an Intraocular Lens during Accommodation Qi Chen; Lin Leng; Meixiao Shen; Jianhua Wang; Fan Lu; Ding Chen View Presentation 2987 - C0078. Reoperation After Resident-Performed Cataract Surgery Shivali A. Menda; Todd Driver; Alexandra E. Neiman; Ayman Naseri; Jay M. Stewart View Presentation 2988 - C0079. Astigmatism analysis in the post-cataract surgery population: a retrospective study Stephan Ong Tone; Cindy C. Law; Joseph J. Ma View Presentation 2989 - C0080. Causes Of Implantable Contact Lens Phakic Intraocular Lens Explantation/Exchange at The King Khaled Eye Specialist Hospital (KKESH) Nasser A. Al Sabaani; Sabah S. Jastaneiah; Saeed A. Al Motowa; Ashley Behrens View Presentation 2990 - C0081. Title Prevalence of Pseudoexfoliation and Complications of Cataract Surgery in an Ethiopian Ancestry Population Leslie S. Jones; Bashira A. Charles View Presentation 2991 - C0082. Outcomes of scleral-fixation of intraocular lenses with fibrin glue Kashif Baig; Paul Bastianelli; Salina Teja View Presentation 2992 - C0083. Clinical Outcomes and Complications of Iris Sutured Posterior Chamber Intraocular Lens Implants Alice Hong; Jocelyn Kuryan; Elaine Wu; David C. Ritterband; John A. Seedor View Presentation 2993 - C0084. Posterior Capsule Management in Pediatric Cataract Surgery W. Jordan Piluek; Douglas R. Fredrick View Presentation 2994 - C0085. Comparison of visual outcomes after implantation of a toric or standard 1piece hydrophobic-acrylic aspheric intraocular lens Don R. Nixon; Kevin Waltz; Debbie Trentacost; Kristen Featherstone; Linda Tsai; Sanjeev Kasthurirangan View Presentation 2995 - C0086. Cataractogenesis and surgical outcome in patients with uveitis Anne-Laure Remond; Emmanuelle Champion; Valérie Touitou; Christine Fardeau; Bahram Bodaghi; Phuc Le Hoang View Presentation 2996 - C0087. Impact of changes in attending staffing on major cataract complications at Veterans Affairs Boston Healthcare System Nikil V. Moodabagil; Jose Efren Gonzalez Monroy; Danielle Trief; Mary K. Daly View Presentation 2997 - C0088. Retina evaluation with non mydriatic ultra wide field color imaging after cataract surgeries in asymptomatic patients Nicholas Faberowski; Hugo Quiroz-Mercado; Carmen Gonzalez; Ramanath Bhandari; Scott Oliver; Jeffrey Olson; Naresh Mandava; Shulamit Schwartz View Presentation 2998 - C0089. Early Uncorrected Vision in Astigmatic Eyes Undergoing Microcoaxial Phacoemulsification with Toric Lens Implantation David Wang; Robert Osher View Presentation 2999 - C0090. Refractive outcome and patient satisfaction after cataract surgery with mutifocal intraocular lens implantation NABIL EL KOUHEN; Heni Mnasri; Shanour premy; Ali Mouna; Adina Agapie; Agathe Ferte; Francois Ameloot; Jean-Marc Perone View Presentation 3000 - C0091. Tonometry in corneal edema after cataract surgery: Rebound versus Goldmann applanation tonometry Matthias Fuest; Nikolaos Mamas; Niklas Plange View Presentation 3001 - C0092. Cataract Prevalence and Cataract Surgery Outcomes in Patients with Ocular Graft-Versus-Host Disease (GVHD) Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 112 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Ujwala S. Saboo; Hasanain Shikari; Reza Dana View Presentation 3002 - C0093. ASSESMENT OF TORIC INTRAOCULAR LENS ALIGNMENT BY RAY TRACING SYSTEM dr. vaibhav sharma View Presentation 3003 - C0094. Long-term stability of intraocular lens and various types of capsular tension ring in eyes with subluxated lens Hyung-Joon Kim View Presentation 3004 - C0095. Utility of intraoperative wavefront aberrometry in post-refractive cataract patients Anjali Tannan; Randy J. Epstein; Vanee Virasch; Parag Majmudar; Charles Faron; Jonathan B. Rubenstein View Presentation 3005 - C0096. Upside-Down ACIOL placement: A case series on complications, management, and outcomes Nisha Chadha; Leslie Olsakovsky; Bryan D. Edgington View Presentation 3006 - C0097. Multifocal IOL implantation in Patients with Uveitis Sandra Hu-Torres; Reena Rasheed; C. Stephen Foster View Presentation 3007 - C0098. MRI of the Capsular Bag in Pseudophakic Human Donor Eyes Lawrence M. Strenk; Susan A. Strenk; Liliana Werner; Nick Mamalis View Presentation 3008 - C0099. Pseudoexfoliation Syndrome is associated with deepening of the anterior chamber in supine position and post-operative hyperopic shift Daniel Feiler; Ryan M. St Clair; Kimberly C. Sippel; Christopher E. Starr View Presentation 3009 - C0100. Cataract and Fuchs Dystrophy Celia v. Zinger; Vincent Borderie View Presentation 3010 - C0101. Straylight changes after lens exchange in eyes with good visual acuity Thomas J. Van Den Berg; Ruth Lapid-Gortzak; Ivanka J. van der Meulen View Presentation 3011 - C0102. Humphrey Visual Field 10-2 performance in eyes with multifocal versus monofocal intraocular lens implants Garrick Chak; Marjan Farid; Sumit Garg; Roger F. Steinert View Presentation 3012 - C0103. Refractive outcome and subjective quality of vision after toric lens implantation in cataract surgery Heni Mnasri; Ali Mouna; NABIL EL KOUHEN; Adina Agapie; Agathe Ferte; Shanour Premy; Francois Ameloot; Pierre-Jean Bertaux; Jean-Marc Perone View Presentation 3013 - C0104. The role of intraocular lens for prevention of secondary cataract formation Masamoto Aose; Koichiro Mukai; Hiroyuki Matsushima; Norihito Gotoh; Senoo Tadashi View Presentation 320. Color Vision, Photoreceptor Function, Adaptation Moderator(s): Elise Dees (Buskerud University College) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM View Session Details 3014 - C0177. Is dark-adapted cone detection optimized given noise and uncertainty? Darren E. Koenig; Heidi J. Hofer View Presentation 8:30 AM - 10:15 AM 3015 - C0178. Quick and easy light sensitivity assessment of the dark adapted eye: The Tuebingen Scotopic Threshold Test (TSTT) Torsten Strasser; Hana Langrová; Anne Kurtenbach; Ditta Zobor; Dominic Hillerkuss; Eberhart Zrenner View Presentation 8:30 AM - 10:15 AM 3016 - C0179. Dark Adaptation and the effect of Oxygen Inhalation in Cystic Fibrosis Rachel Hiscox; Christine Purslow; Rachel V. North; Ian Ketchell; Katharine Evans View Presentation 8:30 AM - 10:15 AM 3017 - C0180. Characteristics of Color Visual Acuity by Step Changes of Background Luminance in Young Subjects of Normal Eyes Yoshiki Tanaka; Kiyoshi Tanaka; Sho Yokoyama; Hideki Nakamura; Kazuo Ichikawa; Shoko Tanabe View Presentation 8:30 AM - 10:15 AM 3018 - C0181. A Color Visual Function Test to Evaluate the Age-Related Changes in Good Visual Acuity of Normal Eyes Sho Yokoyama; Kazuo Ichikawa; Hideki Nakamura; Shoko Tanabe; Yoshiki Tanaka; Kiyoshi Tanaka; Rie Horai View Presentation 8:30 AM - 10:15 AM 3019 - C0182. Training for Identification of Colors Altered by Colored Filters Thomas Kuyk; Alastair Smith; Semih Kumru View Presentation 8:30 AM - 10:15 AM 3020 - C0183. Investigation of color vision defect among dental practitioners Hani Alarify; Nasser Aldossari; Ahmed Alharbi; Ali Masmali; Turki Almubrad View Presentation 8:30 AM - 10:15 AM 3021 - C0184. Dependence of the color brown on the spatial configuration of high luminance surrounds Tanner DeLawyer; Ariel Frederick; Simon Kaplan; Tracy Lin; Sophie Shonka; Steven L. Buck View Presentation 8:30 AM - 10:15 AM 3022 - C0185. Frequency of atypical genotypes associated with normal and defective color vision Candice Davidoff; Jay Neitz; Maureen Neitz View Presentation 8:30 AM - 10:15 AM 3023 - C0186. Rod Hue Biases for Foveal Stimuli on CRT Displays Katharina G. Foote; Steven L. Buck View Presentation 8:30 AM - 10:15 AM 3024 - C0187. Fundus-controlled two-color adaptometry with the Microperimeter MP1 Wadim Bowl; Birgit Lorenz View Presentation 8:30 AM - 10:15 AM 3025 - C0188. Color Discrimination and Visual Perimetry Evaluation in Multiple Sclerosis and Neuromyelitis Optica Phelipe A. Paixao; Lorena B. Botelho Vergara; Lucas Daniel A. Almeida Fernandes; Eliza Maria C. Lacerda; Givago S. Souza; Hideraldo Luis Souza Cabeça; Alexandre A. Rosa; Luiz Carlos L. Silveira View Presentation 8:30 AM - 10:15 AM 3026 - C0189. Psychophysical and electrophysiological evaluation of visual function in type 1 diabetics Valéria D. Garcia; Mirella Gualtieri; Mirella T. Barboni; Daniela M. Bonci; Thiago L. Costa; Balázs V. Nagy; Sérgio T. Rodrigues; Ana L. Moura; Francisco Max Damico; Dora F. Ventura View Presentation 8:30 AM - 10:15 AM 3027 - C0190. Psychophysical Measurement of Rod and Cone Thresholds in Stargardt Disease with Full-Field Stimuli Frederick T. Collison; Gerald A. Fishman; J Jason McAnany; Jana Zernant ; Rando Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 113 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Allikmets View Presentation 3028 - C0191. Laser Eye Protection and Visibility of Multi-Function Displays Martin LaFrance; Craig A. Williamson; Leedjia Svec; Thomas Kuyk View Presentation 3029 - C0192. Chromatic components in underwater targets do not affect Great cormorants’ (Phalacrocorax carbo) visual resolution Gadi Katzir; Ruth Almon; Ido Izhaki View Presentation 3030 - C0193. High Throughput Behavioral Estimates of Visual Thresholds in Mice in a Watermaze with Cued Escape Platform Arkady Lyubarsky; Muhammad Sheheryar Khan; Meera Sivalingam; Jean Bennett View Presentation 321. Anatomy Moderator(s): Falk Schroedl (Paracelsus University Salzburg) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 3031 - C0194. Clinical and Histopathologic Characteristics in Floppy Eyelid Syndrome Karin U. Loeffler; Nina Stratmann; Teresa Maeueler; Frank G. Holz; Martina C. Herwig View Presentation 3032 - C0195. Spatial Relationship between Bruch’s Membrane Opening and Lamina Cribrosa Determines Optic Disc Tilting Pat-Michael Palmiero; Sung Chul Park; Yiyi Liu; Camila F. Netto; Rafael L. Furlanetto; Mohammed Al-Jumayli; Jeffrey M. Liebmann; Robert Ritch View Presentation 3033 - C0196. Endothelial Glycocalyx Layer in the Aqueous Outflow Pathway of Bovine Eyes Chen-Yuan C. Yang; Tiffany Huynh; Mark Johnson; Haiyan Gong View Presentation 3034 - C0197. Comparative Ocular Anatomy & Age-Related Ocular Changes of the Western Lowland Gorilla Clay Holley; Nick Hogan View Presentation 3035 - C0198. Assessment of ciliary muscle morphology using a new Fourier domain swept source anterior chamber optical coherence tomographer Phillip Buckhurst; Hetal Buckhurst; Catriona Hamer View Presentation 3036 - C0199. Comparative Anatomy of Trabeculum and Smooth Zone (Schwalbe's Line) Widths of Various Primate and non-Primate Eyes by Scanning Electron Microscopy (SEM) Ann E. Barker-Griffith; Jerrold L. Abraham; Hengsheng Fang; Mark P. Breazzano View Presentation 3037 - C0200. Cell-ECM interactions during formation of the zebrafish hyaloid vasculature Andrea E. Hartsock; Jeffrey M. Gross View Presentation 3038 - C0201. Dimensional Variation of the Orbicularis Oculi Muscle in Non-preserved, Fresh Frozen Human Cadavers Bryan R. Costin; Natta Sakolsatayadorn; Stephen A. McNutt; Tal Rubinstein; George Trichonas; Jennifer M. McBride; Julian D. Perry View Presentation 3039 - C0202. Ocular Effects of Blood Collection Techniques in Rabbits Shwu-Fei Lee; Steven D. Sorden; Dale G. Dunn; Peter J. Sonnentag; Alexander J. Dwyer View Presentation 3040 - C0203. The Use of Commercially Available Grafts in Lower Eyelid Reconstruction Neel Kumar; Shalin Shah; Adham B. al-Hariri View Presentation 3041 - C0204. Outcomes of surgery for removal of visually significant hyperplastic persistent pupillary membranes Courtney L. Kraus; Gregg T. Lueder View Presentation 3042 - C0205. Anatomical and Histologic Evaluation of the Frontalis Muscle in NonPreserved, Fresh-Frozen Cadavers Stephen A. McNutt; Bryan R. Costin; Thomas Plesec; Natta Sakolsatayadorn; Tal Rubinstein; George Trichonas; Jennifer M. McBride; Julian D. Perry View Presentation 3043 - C0206. Primary Blast-Induced Ocular Trauma Modulated by Peak Pressure Daniel Sherwood; Brian Lund; Randolph D. Glickman; Walter Gray; Richard Watson; Kimberly Thoe; William E. Sponsel; Matthew A. Reilly View Presentation 3044 - C0207. Positional Relationship Between the Ethmoidal Foramina and the Optic Canal Eric S. Ahn; Milap Mehta; Julian D. Perry View Presentation 3045 - C0208. A Computational Model for Investigation of Ocular Trauma Due to Primary Blast Walter Gray; Richard Watson; Matthew A. Reilly; Brian Lund; Rick E. Sponsel; Randolph D. Glickman View Presentation 3046 - C0209. Endonasal mitomicyn-C during diode laser transcanalicular dacryocystorhinostomy Jorge E. Peraza Nieves; Johnny Javier Castellar Cerpa; Paula Arribas Pardo; Paula Bañeros; Juan Antonio Troyano Rivas; Angel Romo Lopez View Presentation 3047 - C0210. Effects of Oxygen Level on In Vitro Culture of Human Choroidal Melanocytes Solange Landreville; Juliane Guay; Florence Pagé-Larivière View Presentation 3048 - C0211. Diurnal Variation of Macular Choroidal Volume in Healthy Volunteers Natalia Alpizar-Alvarez; Erick Hernandez-Bogantes; Lihteh Wu View Presentation 3049 - C0212. Evaluating Choroidal Microvascular Angiogenesis by Choroid Sprouting Assay Zhuo Shao; Mollie Friedlander; Christian G. Hurst; Zhenghao Cui; Lucy Evans; Jing Chen; Przemyslaw Sapieha; Sylvain Chemtob; Jean-Sebastien Joyal; Lois E. Smith View Presentation 3050 - C0213. Distribution, morphology, and dynamic behavior of macrophages in the adult mouse choroid Anil Kumar; Lian Zhao; Minhua Wang; Robert Fariss; Wai T. Wong View Presentation 3051 - C0214. Mast Cell Degranulation in AMD Choroid Gerard A. Lutty; Imran A. Bhutto; Johanna M. Seddon; D. S. McLeod View Presentation 3052 - C0215. The Adult DCX-dsRed Transgenic Rat Retina: Characterization of DsRed Positive Cells Andrea Trost; Falk Schroedl; Barbara Bogner; Clemens Strohmaier; Christian Runge; Guenther Grabner; Ludwig Aigner; Herbert A. Reitsamer View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 114 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 3053 - C0216. Lipid Peroxidation in the Rat Retina after Elevated Intraocular Pressure Karen M. Joos; Raymond Mernaugh; Ratna Prasad; Pengcheng Lu; Lyman Roberts View Presentation 3054 - C0217. Detection of the neuroregulatory peptide alarin in cranial autonomic ganglia of the rat Falk Schroedl; Alexandra Kaser-Eichberger; Andrea Trost; Clemens Strohmaier; Barbara Bogner; Christian Runge; Barbara Kofler; Herbert A. Reitsamer View Presentation 3055 - C0218. Immunohistochemical Features of Encapsulated Blebs Following Ahmed Glaucoma Valve Implantation fatima fikri; Deepak P. Edward; Sami a. Al Shahwan; Khitam Al Hati; Ibrahim Al Jadaan View Presentation 3056 - C0219. Functional interactions between Mmp-2 and Mmp-14a during axonal innervation in the developing and regenerating zebrafish optic tectum Inge Van Hove; Els Janssens; Djoere Gaublomme; Kim Lemmens; Lieve K. Moons View Presentation 3057 - C0220. Dissecting the primary site of pathogenesis in COL4A1 related anterior segment dysgenesis Mao Mao; Douglas B. Gould View Presentation 3058 - C0221. Effects of Retinopathy of Prematurity (ROP) on Intraocular Structures James D. Akula; Robert J. Munro; Anne Moskowitz; Ronald M. Hansen; Toco Y. Chui; Sanjay P. Prabhu; Anne B. Fulton View Presentation 3059 - C0222. PTF1a in anterior eye development in zebrafish C Denwood; Nisha Kheradiya; Na Luo; Michael Conwell; Ryan M. Anderson; Yang Sun View Presentation 3060 - C0223. Pathologic features, expression and activity of MMPs in sclera from patients with nanophthalmos Jing Tao; Ningli Wang View Presentation 3061 - C0224. Development, Composition, and Architecture of the Mouse Ciliary Zonule Steven Bassnett; Alicia De Maria; Yanrong Shi View Presentation 3062 - C0225. Closing the gap: development of a novel zebrafish-based tool to assess optic fissure closure Pamela R. Pretorius; Yusuf Agamawi; Julia M. Hatler; Stephanie L. Lerach; Fei Qi; Bo Zhang; Brent R. Bill; Shuo Lin; Lisa A. Schimmenti View Presentation 3063 - C0226. Congenital eye defects due to failure of embryonic eyelid closure Qinghang Meng; Maureen Mongan; Jinling Zhang; Ying Xia View Presentation 3064 - C0227. The Developmental Roles of c-Jun in Ocular Surface Epithelium Maureen Mongan; Qinghang Meng; Winston Kao; Ying Xia View Presentation 3065 - C0228. The functional significance of zinc-finger protein Nlz2 in optic fissure closure Grace Shih; Ramakrishna Alur; Felix I. Onojafe; Brian P. Brooks View Presentation 322. Corneal Surgery Non-refractive I Moderator(s): Frank Larkin (Moorfields Eye Hospital) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 3066 - D0001. A quantitative approach to evaluate the overall quality of cornea used in a comparative study between two hypothermic storage media Mohit N. Parekh; Gianni Salvalaio; Stefano Ferrari; Marie-Claude Amoureux; Cecile Albrecht; Denis Fortier; Diego Ponzin View Presentation 3067 - D0002. Assessment of The Quality of Life and Psychometric Assessment After Keratoplasty with VFQ-25 Daisuke Tomida; Yumiko HIrayama; Seika Den; Kenji Konomi; Yoshiyuki Satake; Jun Shimazaki View Presentation 3068 - D0003. Two year visual acuity and contrast sensitivity outcome following Descemet’s Stripping Automated endothelial keratoplasty (DSAEK) and the correlation with preoperative donor graft thickness Fiona Pin Miao P. Lim; Marcus Ang; Hla M. Htoon; Donald T. Tan; Jodhbir S. Mehta View Presentation 3069 - D0004. Comparison of Dehydration Kinetics of Organ Cultured Human Corneas by Different Deswelling Media using Optical Coherence Tomography Martin Hermel; Sabine Salla; Nicole Hamsley; Peter Walter; Anne C. Rieck View Presentation 3070 - D0005. The influence of donor factors on suitability of corneas for penetrating keratoplasty John Armitage; Mark N. Jones; Isaac Zambrano; Fiona M. Carley; Derek M. Tole View Presentation 3071 - D0006. Comparison of Neovascularization, Opacification and Cornea thickness in a Rabbit Model of Keratoplasty with Interrupted or Continuous Suture Techniques by Cornea fluorescein angiography and corneal OCT Maria A. Parker; Trevor J. McFarland; Winston Chamberlain ; Scott Ellis; Kyriacos Mitrophanous; Tim Stout View Presentation 3072 - D0007. Most frequent indications for keratoplasty at 2 academic centers over a 6year period Kimberly Hsu; Shu-Hong Chang; Whitney Brothers; Sean L. Edelstein; Hugo Y. Hsu; George J. Harocopos View Presentation 3073 - D0008. Outcome of Combined Penetrating Keratoplasty and Vitreoretinal Surgery using Temporary Eckardt Keratoprosthesis and Analysis for Factors affecting Corneal Allograft Survival Dae Seung Lee; Jang won Heo; Mee Kum Kim; Hyuk Jin Choi; Won Ryang Wee; Joo Youn Oh View Presentation 3074 - D0009. Comparison Of Graft Survival Following Penetrating Keratoplasty And Descemet’s Stripping Endothelial Keratoplasty In Medically And Surgically Treated Glaucoma Patients George C. Papachristou; David S. Greenfield; Terrence P. O'Brien; Joyce C. Schiffman; Wei Shi; Shawn M. Iverson View Presentation 3075 - D0010. Self-retained amniotic membrane for high-risk penetrating keratoplasty one-year results Pho Nguyen; Ramya N. Swamy; Kelly Rue; J M. Heur; Samuel C. Yiu View Presentation 3076 - D0011. Anterior Chamber Depth and Penetrating Keratoplasty Graft Survival Christine N. Pham Lagler; Wuqaas M. Munir View Presentation 3077 - D0012. A new anvil profile in femtosecond laser assisted penetrating keratoplasty Luca Menabuoni; Ivo Lenzetti; Annalisa Canovetti; Alex Malandrini; Francesca Rossi; Roberto Pini Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 115 sur 222 View Presentation 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 3078 - D0013. Sutureless Penetrating Keratoplasty Using a Femtosecond Laser. A Laboratory Approach Ashley Behrens; Hind M. Alkatan; Emad Badawy; Farhan Alanazi; Nasser Alsabaani; ABDULMAJED ALJAETHEN View Presentation 3079 - D0014. Descemet’s Membrane Endothelial Keratoplasty (DMEK) : Over-stripping the graft bed promotes donor adherence Michael D. Straiko; Mark A. Terry; Julia Talajic; David Davis-Boozer View Presentation 3080 - D0015. Pachymetry Assisted Lamellar Keratoplasty for Corneal Ectasia Julio C. Hernandez-Camarena; Victor M. Boullosa; Alejandro Navas; Arturo J. RamirezMiranda; Cesar Carriazo; Enrique O. Graue-Hernández View Presentation 3081 - D0016. DSAEK & DMEK Triples: How close are we to achieving emmetropia? David Davis-Boozer; Mark A. Terry; Michael D. Straiko; Julia Talajic; Asem A. Alqudah; Mark A. Greiner View Presentation 3082 - D0017. Surface topography and 3-dimensional Confocal Profiling of Femtosecond and Mechanical Microkeratome Dissected Posterior Human Corneal Buttons mor m. dickman; Marc P.F.H.L. van Maris; Tos TJM Berendschot; Rudy M. Nuijts View Presentation 3083 - D0018. Use of intraoperative Optical Coherence Tomography to evaluate grafthost interface separation in Descemet Stripping Automated Endothelial Keratoplasty Katie Hallahan; Gina M. Smith; Justis P. Ehlers; Jeff Goshe View Presentation 3084 - D0019. Comparison of time-domain with spectral-domain OCT for detection of graft detachments following DMEK Philipp Steven; Carolin Le Blanc; Sebastian E. Siebelmann; Ludwig M. Heindl; Claus Cursiefen View Presentation 3085 - D0020. In Vivo Confocal Microscopy to Detect the Wound Healing Process after DSAEK and nDSAEK Jen-Pin Sun; Wei-Li Chen; Ying-Han Lin; Chien-Tzu Peng; Fung-Rong Hu View Presentation 3086 - D0021. Reproducibility of graft preparations in Descemet membrane endothelial keratoplasty Kathrin Rössler; Ursula Schlotzer-Schrehardt; Bjoern O. Bachmann; Friedrich E. Kruse View Presentation 3087 - D0022. Low-energy and high-frequency femtosecond laser in the production of donor corneal lamellae Gustavo Victor; Walton Nosé; Sidney J. Sousa; Milton R. Alves View Presentation 3088 - D0023. Tears of post-LASIK corneal donor tissue during surgeon-performed donor graft preparation for DSAEK Drew Davis; Peter A. Karth; Christopher Croasdale; Steven B. Koenig View Presentation 3089 - D0024. DSAEK for Corneal Decompensation After Ex-Press Shunt Surgery -A Case Series Jayne S. Weiss; Shalin Shah; Hilary Thompson; Christina Bovone View Presentation 3090 - D0025. Morphological study of posterior corneal grafts obtained for DSAEK comparing two different harvesting techniques Juan A. Duran; Elío Díez-Feijóo View Presentation 3091 - D0026. DSAEK: Endothelial cell loss is greater for Pseudophakic Bullous Keratopathy than for Fuchs’ Dystrophy Julia Talajic; Mark A. Terry; Michael D. Straiko; Asem A. Alqudah; David Davis-Boozer View Presentation 3092 - D0027. Changes in contrast sensitivity and color vision after Descemet membrane endothelial keratoplasty Javier Cabrerizo; Korine van Dijk; Paulien Leeuwenburgh; Fayyaz U. Musa; J Aritz Urcola; Gerrit RJ Melles View Presentation 3093 - D0028. Risk Factors for Adjuvant Glaucoma Therapy and Graft Failure in Descemet’s Stripping Automated Endothelial Keratoplasty Patients Carrie Zaslow; Paul Petrakos; Allison Angelilli; Ira J. Udell; Carolyn Shih View Presentation 3094 - D0029. Descemet’s Membrane Endothelial Keratoplasty (DMEK): Early results using eye bank prepared, pre-stripped donor tissue in the first 43 cases Mark A. Terry; Michael D. Straiko; Julia Talajic; David Davis-Boozer View Presentation 3095 - D0030. Adverse effects of Systemic Cyclosporin A in High-risk Keratoplasty Jong Joo Lee; Mee Kum Kim; Won Ryang Wee View Presentation 3096 - D0031. Immediate postoperative local Descemet membrane detachments and interface fluid pockets after DMEK vary in location and degree as shown by optical coherence tomography Carolin Le Blanc; Sebastian E. Siebelmann; Ludwig M. Heindl; Claus Cursiefen; Philipp Steven View Presentation 3097 - D0032. The comparative analysis of clinical outcome in penetrating keratoplasty in use of domestic or imported cornea from United-States in South Korea Ja Young Lee; Mee Kum Kim; Joo Youn Oh; Hyuk Jin Choi; Won Ryang Wee View Presentation 3098 - D0033. Outcomes of Thin Lenticule Descemet Stripping Automated Endothelial Keratoplasty using a Single-Pass Microkeratome technique Prafulla K. Maharana; Namrata Sharma; Rasik B. Vajpayee View Presentation 3099 - D0034. Clinical outcome of repeat penetrating keratoplasty Margareta Claesson; John Armitage View Presentation 3100 - D0035. Femtosecond Laser "Mini-Bubble" Deep Lamellar Dissection for DALK and DSAEK Roger F. Steinert; Marjan Farid; Sumit Garg; Matthew Wade View Presentation 3101 - D0036. Corneal thickness after posterior lamellar keratoplasty Anders Ivarsen; Jesper Hjortdal; Nicolaj Aagaard; J.Christian Hedegaard; Henrik Sejersen; Christina Møller View Presentation 323. Corneal Surgery Refractive Moderator(s): Olivier Richoz (Geneva University Hospital) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM View Session Details 3102 - D0037. Role of Subconjunctival Bevacizumab in Post-Pterygium Excision Management Sonia B. Dhoot; Howard Guan; Keith Tokuhara View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 116 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 3103 - D0038. The effect of pterygium surgery on corneal astigmatism Clinton J. Duncan; Sarah Logan; Kent L. Anderson View Presentation 3104 - D0039. Pterygiums: A Resident Experience with Recurrence and Complications Adam Sise; Tanuj Banker; Wellington Chang; Sasikala Pillai View Presentation 3105 - D0040. Comparison of fibrin glue and autologous blood for conjunctival autograft fixation in pterygium surgery Salina Teja; Sophie Boucher; Kashif Baig View Presentation 3106 - D0041. Expression of the pro-inflammatory molecule RAGE in human pterygia Elia J. Duh; Samar A. Al-Swailem; Zhenhua Xu; Samuel C. Yiu; Lijuan Wu View Presentation 3107 - D0042. Effect of Porcine Chondrocyte Derived Extracellular Matrix on the Pterygium in Mouse Model Kyeong Hwan Kim; Hye Sook Lee; Jae Wook Yang View Presentation 3108 - D0043. Linear systems analysis of Pre and Post Operative Zernike Coefficients in LASIK Surgery Daniel R. Neal; Thomas D. Raymond; Amelia Saliba; Jill V. Treyes View Presentation 3109 - D0044. A novel model of digitized clinical validation of femtosecond LASIK flap diameter and opaque bubble layer (OBL) incidence Ioanna Kontari; George Asimellis; A. John Kanellopoulos View Presentation 3110 - D0045. The effect of procedure room temperature and humidity on LASIK outcomes Michael I. Seider; Stephen D. McLeod; Travis Porco; Steven C. Schallhorn View Presentation 3111 - D0046. Post-keratoplasty astigmatism correction with Toric Intraocular Lenses Matthew Wade; Roger F. Steinert; Sumit Garg; Marjan Farid View Presentation 3112 - D0047. Comparison of Laser-Assisted Removal of Epithelium to Mechanical Debridement in Corneal Cross-Linking for Progressive Keratoconus: 12-Months Results Ana Laura C. Canedo; Ronald N. Gaster; Yaron S. Rabinowitz View Presentation 3113 - D0048. Pachymetry map of corneal epithelium in patients wearing orthokeratology contact lenses Yishan Qian View Presentation 3114 - D0049. Patient Satisfaction and Quality of Vision after Wavefront-guided (WFG) vs. Wavefront-optimized (WFO) LASIK Rose K. Sia; Richard D. Stutzman; Joseph F. Pasternak; Denise S. Ryan; Jennifer B. Eaddy; Lorie A. Logan; Lamarr Peppers; Edward W. Trudo; Kraig S. Bower View Presentation 3115 - D0050. Biomechanical changes in Human Corneas after Low and High Intensity Collagen Cross-Linking Treatment measured using Scanning Acoustic Microscopy Ithar M. Beshtawi; Riaz Akhtar; Chantal Hillarby; Clare O'Donnell; Xuegen Zhao; Arun Brahma; Fiona M. Carley; Brian Derby; Hema Radhakrishnan View Presentation 3116 - D0051. Inflammatory and lacrimal gland proteins in the tear film after femtosecond LASIK Andrea Petznick; Lei Zhou; Roger W. Beuerman; Siew Kwan Koh; Louis Tong; Jodhbir S. Mehta View Presentation 3117 - D0052. The PEDF neuroprotective domain plus DHA selectively induces corneal nerve regeneration after experimental surgery Maria S. Cortina; Jiucheng He; Azucena H. Kakazu; Nicolas G. Bazan; Haydee E. Bazan View Presentation 3118 - D0053. A limitation of Hartmann-Shark system in measuring wavefront aberrations for patients received laser refractive surgery Ying Wu; Ji C. He; Xingtao Zhou; Renyuan Chu View Presentation 3119 - D0054. Correlation of Temperature and Humidity to the Incidence of LASIK Flap Striae In A Very High Volume Refractive Surgery Center Neema Nayeb-Hashemi; Ronald R. Krueger; Minoru Tomita View Presentation 3120 - D0055. Flap-induced aberrations for the LASIK refractive surgery Stan Bentow; Anatoly Fabrikant; Guang-ming G. Dai View Presentation 3121 - D0056. Correlation between the changes in corneal power and visual outcome following inlay implantation Eon Kim; Klaus Ehrmann; Jukka A. Moilanen; Jennifer D. Choo; Sylvie Franz View Presentation 3122 - D0057. Evaluation of femtosecond laser-assisted combined Descemet’s stripping automated endothelial keratoplasty (DSAEK) and astigmatic keratotomy (AK) surgery Kathy M. Tran; Silas Wang; Ioanna Kontari; George Asimellis; A. John Kanellopoulos View Presentation 3123 - D0058. Photorefractive keratectomy after deep anterior lamellar keratoplasty Pichaporn Artornsombudh; Yakov Goldich; Noa Avni-Zauberman; Uri Elbaz; Setareh Ziai; David Rootman View Presentation 3124 - D0059. Comparison of the Ocular Response Analyzer and the Belin-Ambrósio Ectasia Display for Detecting Eyes at High Risk of Developing Ectasia After Refractive Surgery Maria Eugenia Vola Ravina; Renato Lisboa; Patricia Schimchak; Kody J. Kishi; Natalie A. Afshari; David J. Schanzlin View Presentation 3125 - D0060. Visual Performance Comparison of Wavefront-optimized and Wavefrontguided Laser in situ keratomileusis (LASIK) Kraig S. Bower; Lamarr Peppers; Rose K. Sia; Richard D. Stutzman; Joseph F. Pasternak; Denise S. Ryan; Edward W. Trudo View Presentation 3126 - D0061. Incidence and Factors Associated with Microbial Keratitis in a Large Cohort of Consecutive Corneal Refractive Surgery Patients Steven C. Schallhorn; Julie M. Schallhorn; Adenay Padilla View Presentation 3127 - D0062. Refractive Surgery for Accommodative Esotropia in Special Needs Children and Adolescents Nicholas Faron; James Hoekel; Lawrence Tychsen View Presentation 3128 - D0063. Is calculation of corneal tissue ablation depth determined by VISX Star S4 IR platform’s algorithm a reliable method? Juan A. Curiel; Cristina Pacheco-Del-Valle; Oscar Baca; Alejandro Babayan; Regina Velasco View Presentation 3129 - D0064. Bilateral Implantation of Hydrogel Corneal Inlays in Hyperopic Presbyopes Adam J. Roy; Alan J. Lang; Tonya Porter; Keith Holliday; Guru Sharma; Arturo Chayet; Edna Favela; Enrique Barragan; Sandra Gomez Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 117 sur 222 View Presentation 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 3130 - D0065. Near Functional Range of a Near Center Hydrogel Corneal Inlay in Presbyopic Subjects Alan J. Lang; Adam J. Roy; Keith Holliday; Tonya Porter; Guru Sharma; Arturo Chayet; Edna Favela; Enrique Barragan; Sandra Gomez View Presentation 3131 - D0066. Longer-term Stability of Refractive Corneal Lenticule Extraction Procedures Compared with LASIK Jesper Hjortdal; Iben Bach Pedersen; Anders Ivarsen View Presentation 3132 - D0067. Modeling of Human Refractions for Refractive Surgery Guang-ming G. Dai View Presentation 3133 - D0068. Evaluation of Limbal Ultrastructure in Twelve Year and Twenty-eight Year Post-operative Keratoconic Corneas Erin Dooley; Steven Gardner; Sally Hayes; Jonathan Harris; Kim Nielsen; Jesper Hjortdal; Thomas Sorensen; Nicholas Terrill; Craig Boote; Keith M. Meek View Presentation 3134 - D0069. Evaluate the safety and efectiveness of the AcrySof Phakic Angle supported intraocular Lens for the correction of high myopia Mireya G. Arellano View Presentation 3135 - D0070. Patient Satisfaction and Quality of Vision after Wavefront-guided (WFG) vs. Wavefront-optimized (WFO) Photorefractive keratectomy (PRK) Denise S. Ryan; Rose K. Sia; Richard D. Stutzman; Joseph F. Pasternak; Lamarr Peppers; Jennifer B. Eaddy; Lorie A. Logan; Edward W. Trudo; Kraig S. Bower View Presentation 3136 - D0071. Comparing the Corneal Biomechanical Stability after LASIK, ReLEx FLEx and ReLEx SMILE with Ultra High Speed Camera (Corvis® ST) Iben Bach Pedersen; Sashia Bak-Nielsen; Anders Ivarsen; Jesper Hjortdal View Presentation 3137 - D0072. Femtosecond (FS) Laser Techniques to Facilitate Deep Anterior Lamellar Keratoplasty (DALK) Perry S. Binder; Roger F. Steinert; James E. Hill; Michael A. Campos View Presentation 3138 - D0073. Refractive surgery evaluation and risk of corneal ectasia, inter-rater agreement and comparison to a new software: the SCORE analyzer Florence Cabot; Sonia H. Yoo; Alain Saad; George Kymionis; Ana Paula Canto; Damien Gatinel View Presentation 3139 - D0074. The effect of high order aberrations on the accuracy of wavefront ablations using LASEK on high myopes Jeff G. Grigsby; Kathy Vasquez; Michael Tschoepe; Thomas R. Walters; Billy Cook; Robert G. Sheets; Dennis K. Neely View Presentation 3140 - D0075. Monocular refractive surgery in patients with anisometropia Alejandro Tamez; Julio C. Hernandez-Camarena; Juan F. Lozano-Ramirez; Guillermo Mendoza; Alejandro Rodriguez Garcia; Jorge E. Valdez View Presentation 3141 - D0076. One Year Quality of Vision Outcomes from a Prospective, Randomized Eye-to-Eye Comparison of Wavefront guided and Wavefront optimized Laser in Situ Keratomileusis (LASIK) using the WaveLight® Allegretto Eye-Q 400 Hz Christopher Sáles; Edward E. Manche View Presentation 3142 - D0077. Tear menisci and corneal subbasal nerve density in patients after Laser In Situ Keratomileusis Liang Hu; Wenjia Xie; Dong Zhang; Jia Chen; Fan Lu View Presentation 3143 - D0078. Microkeratome-related complications in the first 10,000 lasik marcos garcia; Breno Barth; Walton Nosé; Breno M. Azevedo; Gustavo Victor; Milton R. Alves View Presentation 3144 - D0079. Laser in situ keratomileusis following the implantation of an anglesupported phakic intraocular lens CRISTINA FERNANDEZ-VIGO ESCRIBANO; Ana Macarro Merino; José Ignacio Fernández-Vigo; José Fernández-Vigo López View Presentation 3145 - D0080. Identification of microorganisms in water samples used in refractive surgery facilities Francisco B. Silva; Cristina V. Niero; Christiane L. Nogueira; Camilla P. Uzam; James D. Lima Junior; Fernando P. Pinto; Antonia Maria O. Machado; Sylvia C. Leão; Denise Freitas; Ana Luisa Hofling-Lima View Presentation 3146 - D0081. Comparison of Optical Quality in Low Myopic and Moderate Myopic Patients Operated With PRK and FemtoLASIK Eric Perez-Campagne; Hana Landoulsi; Damien Gatinel View Presentation 3147 - D0082. Comparative Effect of corneal curvature on acurracy of Intraocular Lens Power Calculation in various fomulars Bo hyuck Kim; Mee Kum Kim; Won Ryang Wee View Presentation 325. Biochemical and Molecular Mechanisms of Diabetic and Retinal Disease Moderator(s): Zsolt Ablonczy (Medical University of South Carolina) and Terri Young (Duke University Eye Center) 11:00 AM - 12:45 PM; 6A 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 View Session Details 3148. Analysis of extracellular vesicles in vitreous samples Bence Gyorgy; Zsuzsanna Récsán; Ágnes Kittel; Krisztina Pálóczi; Lilla Turiák; Károly Vékey; Janos Nemeth; Edit I. Buzas; Zoltán Zsolt Nagy View Presentation 3149. Nephrocystin-5 knockout mice recapitulate retina and kidney pathologies of Senior-Løken Syndrome Cecinio Ronquillo; Jeanne M. Frederick; Wolfgang Baehr View Presentation 3150. Long-term preservation of immature cone-like photoreceptors in a mouse model of human LCA caused by dominant CRX frameshift mutation Jerome E. Roger; Avinash H. Hiriyanna; Debbie F. Cheng; Norimoto Gotoh; Rinki Ratna Priya; Matthew Brooks; Harsha K. Rajasimha; Bo Chang; Anand Swaroop View Presentation 3151. Natriuretic peptides regulate MAP kinases via PKG to protect the RPE from VEGF action Zsolt Ablonczy; Mohammad Dahrouj; Yueying Liu; Kumar Sambamurti; Craig E. Crosson View Presentation 3152. Restoration of vitreous structure after degradation Ying-Bo Shui; Benjamen Filas; Qianru Zhang; Shaili Sharma; Alyssa Panitch; David C. Beebe View Presentation 3153. Insulin Stimulates Increased Production of Soluble Betacellulin in Retinal Pigment Epithelium Cells Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 118 sur 222 PM Bailey Y. Shen; Mariya Ali; Alecia Cutler; Bela Anand-Apte View Presentation 326. Biomechanics Moderator(s): Julie Albon (Cardiff Univ), Mark Lesk (University of Montreal ) and John Flanagan (Univ of Toronto,Toronto Western Hosp) 11:00 AM - 12:45 PM; 6B 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM 3154. Temporal Relationships in Structural Changes of the Optic Nerve Head and Macula in Experimental Glaucoma in Non-Human Primates Nimesh B. Patel; Ronald S. Harwerth View Presentation 3155. Racial variation in the structure of the lamina cribrosa and sclera within 3-D fluorescent reconstructed optic nerve heads (ONH) from normal human donor tissue Christopher A. Girkin; Massimo A. Fazio; Hongli Yang; Lan Wang; Brandon Smith; Chad C. Cheetham; Claude F. Burgoyne; J Crawford C. Downs View Presentation 3156. Racial Differences in Mechanical Strain in the Posterior Human Sclera Massimo A. Fazio; Rafael Grytz; Luigi Bruno; Jeffry S. Morris; Christopher A. Girkin; J Crawford C. Downs View Presentation 3157. Peripapillary Sclera (ppS) and Lamina Cribrosa (LC) 3D Strain Mapping in Highand Normal-tension Glaucoma Patients following IOP Lowering by Trabeculectomy (TE) Michael J. Girard; Nicholas G. Strouthidis View Presentation 3158. IOP Elevation Reduces the Waviness of the Load Bearing Collagen Fibers in the Lamina Cribrosa Ian A. Sigal; Jonathan L. Grimm; Ning-Jiun Jan; Richard A. Bilonick; Gadi Wollstein; Larry Kagemann; Hiroshi Ishikawa; Joel S. Schuman; Katherine A. Davoli; Kira L. Lathrop View Presentation 3159. IOP Exposure Determines Scleral Shell Strain Changes in Nonhuman Primate (NHP) Experimental Glaucoma J Crawford C. Downs; Massimo A. Fazio; Michael J. Girard; Claude F. Burgoyne View Presentation 3160. Optic Nerve Head (ONH) Lamina Cribrosa Insertion Migration and Pialization in Moderate and Severe Non-human Primate (NHP) Experimental Glaucoma (EG) Hongli Yang; Ruojin Ren; Galen Williams; Howard Lockwood; J Crawford C. Downs; Stuart K. Gardiner; Claude F. Burgoyne View Presentation 327. Imaging: Advances in Imaging and Diagnostic Moderator(s): Ursula Schmidt-Erfurth (Medical University of Vienna ) and Michael Abramoff (Univ of Iowa Hospitals & Clinics) 11:00 AM - 12:45 PM; 6C 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM 11:00 AM - 11:15 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM View Session Details 3161. In Vivo Choroidal Micro-vasculature Imaging by High-penetration Optical Coherence Angiography Kazuhiro Kurokawa; Young-Joo Hong; Shuichi Makita; Yoshiaki Yasuno View Presentation 3162. Posterior Pole Choroidal Vasculature (CV) Assessed By Automated Choroidal Vessel Segmentation In Standard Clinical Spectral-Domain Optical Coherence Tomography (SD-OCT) In Patients With Diabetic Macular Edema (DME) Bianca S. Gerendas; Sebastian M. Waldstein; Bilal Haj Najeeb; Li Zhang; Hrvoje Bogunovic; Michael D. Abramoff; Christian Simader; Milan Sonka; Ursula SchmidtErfurth View Presentation 3163. Nonmydriatic Ultrawide Field Retinal Imaging Reduces Ungradable Rate, Increases Retinopathy Detection and Reduces Image Evaluation Time in an Ocular Telehealth Program for Diabetic Retinopathy Ahmed F. Omar; Paolo S. Silva; Jerry Cavallerano; Kristen Hock; Ann M. Tolson; Nour Haddad; Jennifer K. Sun; Lloyd M. Aiello; Lloyd P. Aiello View Presentation 3164. Ultra-Widefield Fundus Autofluorescence Imaging in Central Serous Chorioretinopathy Vinnie P. Shah; David Sarraf; K Bailey Freund View Presentation 3165. Simultaneous 3D Doppler and Polarization Imaging of Macular Pathologies by Polarization-Sensitive Optical Coherence Angiography Young-Joo Hong; Masahiro Miura; Myeong Jin Ju; Shuichi Makita; Yoshiaki Yasuno View Presentation 3166. Polarimetric imaging of geographic atrophy in age-related macular degeneration by polarization sensitive SLO and OCT Masahiro Miura; Ann E. Elsner; Young-Joo Hong; Takuya Iwasaki; Shuichi Makita; Yoshiaki Yasuno View Presentation 3167. Enhanced Vitreal Imaging of the Vitreoretinal Interface in Normal Eyes Using Swept-Source OCT Jonathan J. Liu; Andre J. Witkin; Mehreen Adhi; Ireneusz Grulkowski; Martin F. Kraus; Chen D. Lu; Joachim M. Hornegger; Jay S. Duker; James G. Fujimoto View Presentation 328. AMD: Long Term Outcomes and Safety of Anti VEGF Moderator(s): Anat Loewenstein (Tel Aviv Medical Center) and Francesco Bandello (Univ Vita Salute-Scient Inst San Raffaele) 11:00 AM - 12:45 PM; 6E AM View Session Details View Session Details 3168. Longer Term Safety Outcomes (4 or More Years) After Initiating Anti-Vascular Endothelial Growth Factor Therapy for Neovascular Age-related Macular Degeneration Erika Tanaka; Voraporn Chaikitmongkol; Susan B. Bressler; Neil M. Bressler View Presentation 3169. Aqueous Vascular Endothelial Growth Factor and Ranibizumab Concentrations after Monthly and Bimonthly Intravitreal Injections of Ranibizumab for Age-Related Macular Degeneration Xiying Wang; Tomoko Sawada; Masashi Kakinoki; Taichiro Miyake; Hajime Kawamura; Yoshitsugu Saishin; Ping Liu; Masahito Ohji View Presentation 3170. Detection of anti-ranibizumab antibodies among exudative AMD patients Nicolas Leveziel; Thibaut Pelat ; Hervé Watier ; Philippe Thullier ; Eric H. Souied View Presentation 3171. Subanalysis of Visual Acuity Outcomes in the Second Year of VIEW Studies Michaella Goldstein; Jean-Francois Korobelnik; Christiane Norenberg; Oliver Zeitz View Presentation 3172. Cerebrovascular risk by intravitreal injections of vascular endothelial growth factor inhibitors for age-related macular degeneration: systematic review of literature and metaanalysis Takashi Ueta; Yasuo Noda; Taku Toyama; Takuhiro Yamaguchi View Presentation 3173. Postoperative bacterial endophthalmitis: tap/inject versus sutureless vitrectomy Thomas P. Lindquist; Lauren B. Mason; John O. Mason; John O. Mason; Gerald Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 119 sur 222 12:30 PM - 12:45 PM McGwin; Carrie Huisingh; Duncan A. Friedman; Robert E. Morris; Matthew H. Oltmanns; Amanda Dinsmore View Presentation 3174. Changing patterns of endophthalmitis at a state-wide service in Australia over a 14 year period Jonathan K. Kam; Rosie Dawkins; Danielle A. Buck; Sukhpal S. Sandhu; Penelope J. Allen View Presentation 329. Inflammatory Tissue Damage and Immunoregulation Moderator(s): Graham Wallace (University of Birmingham) and Eric Pearlman (Case Western Reserve University) 11:00 AM - 12:45 PM; 606/607 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM View Session Details 3175. Dendritic Cell-produced TSLP Links Microbial Pathogens to Allergic Inflammation De-Quan Li; Zhitao Su; Lili Zhang; Jing Lin; Cintia S. De Paiva; Stephen C. Pflugfelder View Presentation 3176. Autoimmune component in glaucoma: IgG autoantibody accumulation, plasma cells and microglia under pro-inflammatory conditions Oliver W. Gramlich; Sabine Beck; Anika Ziegler; Norbert Pfeiffer; Franz H. Grus View Presentation 3177. Ocular Pathology and Immunopathology of Blau's Syndrome: First Cases David S. Bardenstein; Atif B. Collins; Faruk Orge; Deepak P. Edward; Elizabeth B. Brooks; Debra A. Goldstein; Rachida Bouhenni; Eric Pearlman; Elias I. Traboulsi View Presentation 3178. Serum Autoantibody Evaluation after Retinal Laser Injury in Mice Yannis M. Paulus; Chuan-Hui Kuo; Kei Morohoshi; Alex Nugent; Luo Luo Zheng; Hiroyuki Nomoto; Mark S. Blumenkranz; Daniel V. Palanker; Santa Ono View Presentation 3179. Promoting CD200R signalling inhibits laser-induced choroidal neovascularisation due to altered proangiogenic macrophage gene expression David A. Copland; Scott J. Robbie; Jian Liu; Wei-Kang Wu; Robin R. Ali; James W. Bainbridge; Andrew D. Dick View Presentation 3180. Paradoxical Role of Caveolin-1 in Retinal Inflammation Michael H. Elliott; Xiaoman Li; Xiaowu Gu; Alaina M. Reagan; Timothy M. Boyce; Ilya Sluch; Md Nawajes A. Mandal; Michelle C. Callegan; Daniel J. Carr View Presentation 3181. Minocycline Prevents Inflammatory Leukocyte Infiltration Following Retinal Ischemia-Reperfusion Injury Steven F. Abcouwer; Sumathi Shanmugam; Cheng-mao Lin; Heather Lindner; Alistair J. Barber; Arivalagan Muthusamy; David A. Antonetti View Presentation 330. From Cytology to Proteomics: New Insights into the Vitreous and Its Role in View Session Details Ocular Disease - Minisymposium Moderator(s): Tatyana Milman (New York Eye and Ear Infirmary), Richard Rosen (New York Eye & Ear Infirmary) and David Wilson (Casey Eye Institute-OHSU) 11:00 AM - 12:45 PM; 608 Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary 11:00 AM - 11:02 Introduction Include in Itinerary 11:02 AM - 11:16 3182. Hyalocytes in Ocular Development and Disease Paul G. McMenamin View Presentation 3183. Proteomics of Embryonic Human Vitreous Development Lloyd P. Aiello View Presentation 3184. Role of Exosomes in Aqueous Humor Dynamics W Daniel Stamer View Presentation 3185. Identification of Protein Biomarkers in Vitreous Humor Following Laser Exposure Rachida Bouhenni View Presentation 3186. Advances in Understanding and Treatment of Diabetic Retinopathy from Vitreous Studies Elia J. Duh View Presentation 3187. Anomalous PVD and Pharmacologic Vitreolysis J Sebag View Presentation 3188. Proliferative Vitreoretinopathy: Od Problem, New Treatments Andrius Kazlauskas View Presentation Discussion Include in Itinerary AM AM 11:16 AM - 11:30 AM 11:30 AM - 11:44 AM 11:44 AM - 11:58 AM 11:58 AM - 12:12 PM 12:12 PM - 12:26 PM 12:26 PM - 12:40 PM 12:40 PM - 12:45 Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary PM 331. Lens Development Moderator(s): Melinda Duncan (University of Delaware) and Michael Robinson (Miami University) 11:00 AM - 12:45 PM; 609 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM View Session Details 3189. Lysine Acetyltransferases CBP and EP300 are Essential for Histone H3 K18 and K27 Acetylation in the Lens Placode and to Determine the Fate of Lens Progenitor Cells Ales Cvekl; Louise V. Wolf; Wilbur R. Harrison; Ying Liu; Qing Xie; Venkatesh Govindarajan; Salil A. Lachke; Ruth Ashery-Padan; David C. Beebe; Paul A. Overbeek View Presentation 3190. Restricted period of Smoothened requirement during lens development Robbert De Iongh; Chaotung Ting; Jing Yee Janet Choi; Gemma Martinez View Presentation 3191. Identification of small MAF family transcription factors MafG and MafK associated with cataract Salil A. Lachke; Smriti Agrawal; Atul Kakrana; Christine A. Dang; Stephanie M. Waters; Abhyudai Singh; Hozumi Motohashi View Presentation 3192. SUMO-Conjugated RanGAP1 Is A Major Lens Protein Regulating MAP Kinase Pathway and MicroRNA Distribution David W. Li; Weike Ji; Xiao-Hui Hu; Wenfeng Hu; Fang-Yuan Liu; Xiangcheng Tang; Kaili Wu; Yizhi Liu; Lili Gong; Mi Deng View Presentation 3193. Double deficiency of Rap1A and B reveals a crucial role for Rap1 in cell adhesive interactions and cell survival, plasticity, polarity and migration events during lens morphogenesis Tharkika Nagendran; Rupalatha Maddala; Vasanth Rao View Presentation 3194. Loss of βA3/A1-crystallin alters normal remodeling of the hyaloid vasculature Debasish Sinha; Mallika Valapala; J S. Zigler; Gerard A. Lutty; Eric F. Wawrousek; Lijin Dong; Stacey L. Hose View Presentation Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 120 sur 222 12:30 PM - 12:45 PM 3195. β1-integrin may be a direct regulator of EGR1 (Early Growth Response 1) within the lens Anne M. Terrell; Melinda K. Duncan View Presentation 332. Risks Associated with AMD Moderator(s): Christine Curcio (Univ of Alabama at Birmingham) and James Handa (Johns Hopkins Wilmer Eye Inst) 11:00 AM - 12:45 PM; 611-614 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM 3196. Human choroidal thickness: Relationship to protease inhibitors Robert F. Mullins; Aditi Khanna; Kai Wang; Megan J. Riker; Edwin M. Stone; Elliott H. Sohn View Presentation 3197. Metabolic impact of cigarette smoke on RPE and Müller cells of complement compromised mice Alexandra D. Butler; William D. Ferrell; Alex S. Woodell; Baerbel Rohrer; Robert E. Marc; Bryan W. Jones View Presentation 3198. Cigarette smoke and RPE injury: role of oxidative stress and ER stress Chuangxin Huang; Joshua J. Wang; Sarah X. Zhang View Presentation 3199. Biometrics and Impact of Basal Linear Deposit (BlinD) in Aging and NonNeovascular Age-Related Macular Degeneration (nnAMD) Christine A. Curcio; Jeffrey D. Messinger; Nancy E. Medeiros; Gerald McGwin View Presentation 3200. Egg or hen: Use of combined light and electron microscopy to reveal whether CC breakdown precedes RPE degeneration in AMD Antje K. Biesemeier; Tatjana Taubitz; Ulrich Schraermeyer View Presentation 3201. In Vivo Imaging of RNA Biomarkers in Choroidal Neovascularization Ashwath Jayagopal; Chauca Moore View Presentation 3202. C1q and Wnt Pathway Expression in Geographic Atrophy Model of ApoB100 Mutant Mice Katayoon B. Ebrahimi; Sonny E. Dike; Christian Gutierez; James T. Handa View Presentation 333. Drug Delivery II Moderator(s): Haiyan Gong (Boston Univ School of Medicine) and Uday Kompella (University of Colorado Denver) 11:00 AM - 12:45 PM; 618-620 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM 11:00 AM - 11:15 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM View Session Details 3203. Deslorelin and transferrin mono- and dual- functionalized nanomicelles for drug delivery to the anterior segment of the eye Trivedi Ruchit; Puneet Tyagi; Sunil K. Vooturi; Uday B. Kompella View Presentation 3204. The Influence of Formulation Factors on Transscleral Iontophoretic Delivery of a Macromolecule in Vitro and in Vivo Sarah A. Molokhia; Kongnara Papangkorn; Charlotte Butler; Donald Mix; John Higuchi; Balbir Brar; S Kevin Li; William I. Higuchi View Presentation 3205. Versatile time-release technology reducing frequency of invasive injections in treating retinal diseases Chi-Chun Lai; Ling Yeung; Lan-Hsin Chuang; Yih-Shiou Hwang; Chih-Chiang Tsai; PoChun Chang; Luke S.S. Guo; Yun-Long Tseng; Sheue-Fang Shih; Keelung Hong View Presentation 3206. Noninvasive Dexamethasone Sodium Phosphate Ocular Drug Delivery System for the Treatment of Intermediate and Posterior Uveitis Kongnara Papangkorn; Donald Mix; Charlotte Butler; John Higuchi; Balbir Brar; William I. Higuchi View Presentation 3207. Ocular Delivery of the Novel Spleen Tyrosine Kinase Inhibitor R406 for Retinoblastoma Eleanor M. Pritchard; Fangyi Zhu; Lei Yang; Cori Bradley; Elizabeth Stewart; Jiakun Zhang; Burgess B. Freeman; Michael Dyer; R. Kip Guy View Presentation 3208. Intravitreal long-lasting micelle formulation of hexadecyloxypropyl-cidofovir (HDPCDV) for cytomegalovirus retinitis Feiyan Ma; Su-Na Lee; Huiyuan Hou; James Beadle; William R. Freeman; Karl Hostetler; Lingyun Cheng View Presentation 3209. Characterization of the In Vitro Release Kinetics of Bevacizumab from a Biocompatible Reverse Thermal Gel Britta M. Rauck; Carlos A. Medina-Mendez; Thomas R. Friberg; Yadong Wang View Presentation 334. Clinical Aspects of Motion Perception - Minisymposium Moderator(s): Peter Bex (Harvard Medical School) and Rigmor Baraas (Buskerud University College) 11:00 AM - 12:45 PM; TCC LL 4/5 AM View Session Details View Session Details 3210. Motion perception in ocular disease and visual dysfunction Peter Bex View Presentation 3211. Motion perception in migraine. Allison M. McKendrick View Presentation 3212. Motion Perimetry Michael Wall View Presentation 3213. Moorfields Motion Displacement Test for Glaucoma David F. Garway-Heath View Presentation 3214. Global motion, suppression and amblyopia Robert F. Hess View Presentation 3215. Peripheral Motion Perception in Low Vision: Characterization of Deficits and the Effects of Training Duje Tadin View Presentation 3216. Motion Perception in Nystagmus Magella M. Neveu View Presentation 335. Corneal Epithelium and Imaging III Moderator(s): Roger Beuerman (Singapore Eye Research Inst) and Matthew Petroll (Univ Texas Southwestern Med Ctr) 11:00 AM - 12:45 PM; TCC 303 View Session Details Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary 28/03/2013 Abstract Central Page 121 sur 222 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM 3217. Binding of transmembrane mucins to galectin-3 limits herpes simplex virus infection Pablo Argueso; Jerome Mauris; Ashley M. Woodward View Presentation 3218. Identification and Validation of PNN-regulated Splicing Events in Human Corneal Epithelial Cells Stephen P. Sugrue; Jeong-Hoon Joo View Presentation 3219. Suture placement on the mouse cornea induces K8 and Muc5ac expression within K12+ corneal epithelial cells Mary Ann Stepp; Gauri Tadvalkar; Victor L. Perez; Yaohong Tan; Sonali Ghosh; James D. Zieske; Albert Lee; Vickery E. Trinkaus-Randall; Ahdeah Pajoohesh-Ganji View Presentation 3220. Corneal Confocal Microscopy detects neuropathy before retinopathy and nephropathy in children with Type 1 Diabetes: A Preliminary Study Mitra Tavakoli; Rayaz A. Malik View Presentation 3221. The Role of Epithelial Remodeling on Refractive Regression after Femtosecond LASIK Karolinne M. Rocha; Ronald R. Krueger View Presentation 3222. 3-Dimensional Assessment of In Vivo Corneal Wound Healing using a Modified HRT-RCM Confocal Microscope Matthew Petroll; Daniela B. Hagenasr; H D. Cavanagh; Danielle M. Robertson View Presentation 3223. Optical coherence tomography (OCT) combined with videokeratography to detect ‘early’ keratoconus – a new “pachymetry/asymmetry” index to quantify disease severity Yaron S. Rabinowitz; Yelena Bykhovskaya; Xiaohui Li; Ana Laura C. Canedo View Presentation 336. Cell and Molecular Biology Moderator(s): Rajiv Mohan (University of Missouri-Columbia) 11:00 AM - 12:45 PM; TCC 304 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM 3224. Cellular cross-talk in the limbal epithelial stem cell niche revealed by highresolution microscopy Julie T. Daniels; Hannah Armer; Hannah J. Levis; Peter M. Munro; Alex J. Shortt; Stephen J. Tuft; Marc Dziasko View Presentation 3225. Pluripotency marker TRA-1-60 is expressed in stromal, perivascular and intraepithelial cells at the human limbus Friedrich E. Kruse; Naresh Polisetti; Johannes Menzel-Severing; Ursula SchlotzerSchrehardt View Presentation 3226. Donor MSCs expressing MHC class II molecule trigger immune responses in an animal model of lacrimal gland chronic graft versus host disease Yoko Ogawa; Shigeto Shimmura; Saori Yaguchi; Takaaki Inaba; Kazuo Tsubota View Presentation 3227. Integral Analysis of Gene Signatures and MicroRNA Expression of Cultured Human Corneal Endothelial Cells in Relation to Their Functions, Cell Senescence, Epithelial-Mesenchymal Transition, and Fibrosis Kazuko Asada; Munetoyo Toda; Michio Hagiya; Kana Nakata; Morio Ueno; Naoki Okumura; Noriko Koizumi; Junji Hamuro; Shigeru Kinoshita View Presentation 3228. CXCR4 Expression Marks Cells in Limbal Stroma with the Potential to Differentiate to Keratocytes James L. Funderburgh; Andrew Hertsenberg; Martha L. Funderburgh; Kira L. Lathrop; Yiqin Du View Presentation 3229. miRNA EXPRESSION PROFILING IN CENTRAL AND LIMBAL DIABETIC AND NORMAL HUMAN CORNEAS USING DEEP SEQUENCING Mehrnoosh Saghizadeh; Jordan Brown; Alexander V. Ljubimov; Vincent A. Funari View Presentation 3230. Standardized cultivation and transplantation of limbal stem cell grafts: Results of a phase I/II clinical trial Nadia Zakaria; Tine Possemiers; Inge Leysen; Jos J. Rozema; Carina Koppen; Zwi Berneman; Marie-Jose B. Tassignon View Presentation 337. Neuro-Ophthalmology: Structural Imaging Studies Moderator(s): Mark Kupersmith (Roosevelt Hospital and NYEE) and Heather Moss (University of Illinois ) 11:00 AM - 12:45 PM; TCC 305 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM View Session Details 3231. Thinning of the Optic Nerve in Aging and after Ischemia: An Imaging Study Using Spectral-Domain Optical Coherence Tomography M. Ali Shariati; Gun Ho Lee; Yaping J. Liao View Presentation 3232. Abnormal Optic Nerve Head Topography in Albinism Imaged Using High Resolution Spectral Domain-Optical Coherence Tomography Frank A. Proudlock; Sarim Mohammad; Viral Sheth; Anastasia Pilat; Helena Lee; Irene Gottlob View Presentation 3233. Early Retinal Ganglion Cell Layer Thinning Due to Acute NAION and Optic Neuritis Mark J. Kupersmith; Mona K. Garvin; Jui-Kai Wang; Randy H. Kardon View Presentation 3234. Regional Spectral-Domain Optical Coherence Tomography Features Better Predict Frisén Scale Grades than Total Volume Alone in Papilledema Jui-Kai Wang; Mohammad Saleh Miri; Randy H. Kardon; Mona K. Garvin View Presentation 3235. Structure-Function Relationship in Optic Nerve Head Drusen Stephanie J. Muylaert; Sung Chul Park; Rafael L. Furlanetto; Yiyi Liu; Camila F. Netto; Rudrani Banik; Jeffrey M. Liebmann; Robert Ritch View Presentation 3236. Retinal vessel diameters in papilledema Heather E. Moss; Gillian Treadwell; Justin Wanek; Mahnaz Shahidi View Presentation 3237. Automated quantification of globe flattening by MRI in Idiopathic Intracranial Hypertension Byron L. Lam; Ahmet M. Bagci; Noam Alperin View Presentation 338. Retinal Degeneration and Neuroprotection Moderator(s): Ellen Townes-Anderson (UMD New Jersey Medical School) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM View Session Details View Session Details 3238 - A0029. Interaction between CEP290 and BBSome genes is required for mediating cilia function in retina Yan Zhang; Arlene V. Drack; Kevin Bugge; Charles Searby; Val C. Sheffield; Seongjin Seo Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 122 sur 222 View Presentation 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 3239 - A0030. High-mobility group box-1 induces decreased brain-derived neurotrophic factor-mediated neuroprotection in the diabetic retina Mairaj Siddiquei; Mohd I. Nawaz; Ahmed Abu El-Asrar View Presentation 3240 - A0031. Inhibition of Transforming Growth Factor β1 (TGF-β1) Using Morpholino Antisense Promotes Repair in Diabetic CD34+ Cells by Modulating the Protein Ubiquitination Pathway Jude Al-Sabah; Valerie Stepps; Stephen Bartelmez; Maria B. Grant; Ashay D. Bhatwadekar View Presentation 3241 - A0032. Myocyte Enhancer Factor 2C (MEF2C) suppresses inflammation in retinal endothelial cells via regulation of KLF2 Zhenhua Xu; Junsong Gong; Takeshi Yoshida; Lijuan Wu; Liudmila Cebotaru; Elia J. Duh View Presentation 3242 - A0033. Prorenin Receptor (PRR) is Regulated by MicroRNA-152 in Human Retinal Endothelial Cells (hRECs) Elizabeth Hur; Annie N. Farrell; Jennifer C. Howell; Rashidul Haque View Presentation 3243 - A0034. Impact of Interleukin-1α on Hyperglycemia-Induced Inflammation and Cell Death in Müller Cells Derrick Feenstra; Prathiba Jayaguru; Charles A. Dinarello; Susanne Mohr View Presentation 3244 - A0035. The anti-ALS drug riluzole attenuates MCP-1 by high glucose, advanced glycation end product (AGE) or TNF-α in cultured human retinal pericytes kyung sook cho; Young Hee Yoon; Jeong A Choi; Jae-Young Koh View Presentation 3245 - A0036. Ischemic conditioning protects from axoglial alterations of the optic pathway induced by experimental diabetes in rats Diego C. Fernandez; Damian Dorfman; Ruth E. Rosenstein View Presentation 3246 - A0037. The Role Of RANTES And Chemokine Receptors In The Retinal Degeneration In Rd Mice Huiyang Zeng; Xingxing Chen View Presentation 3247 - A0038. Effect of enriched environment housing on glutamate-induced damage in adult rat retina Damian Dorfman; Diego C. Fernandez; Monica S. Chianelli; Marcos L. Aranda; Ruth E. Rosenstein View Presentation 3248 - A0039. Neuropeptide Y protects ganglion cells against excitotoxicity and modulates microglia activation in the rat retina Antonio F. Ambrosio; Filipe Elvas; Maria H. Madeira; Tiago Martins; João Martins; Dan Brudzewsky; Cláudia Cavadas; Ana Raquel Santiago View Presentation 3249 - A0040. Neuroprotective effects of siRna, targeted caspase 3 on rat retinal damage induced by different time course of transient Ischemic Injury Shinichiro Ishikawa; Akira Hirata; Jo Nakabayashi; Ryo Iwakiri; Satoshi Okinami View Presentation 3250 - A0041. Neuroprotective Effect of DHEA-derivative BNN27 against N-Methyl-DAspartate-induced Retinal Excitotoxicity in Mice Pavlina A. Tsoka; Ioannis Charalampopoulos; Achilleas Gravanis; Demetrios Vavvas; Miltiadis K. Tsilimbaris View Presentation 3251 - A0042. Leukemia inhibitory factor expression can be induced by agonist of TLR-2 or gp130, and may require NF-kappa B or STAT3 binding to promoter elements Jiangang Wang; Jing Zhang; John D. Ash View Presentation 3252 - A0043. Poly-ADP-glycohydrolase (PARG) expression in wild-type and PARG-110 knock-out retina Ayse Sahaboglu Tekgoz; Naoyuki Tanimoto; Sylvia Bolz; Marina Garcia Garrido; Mathias W. Seeliger; Eberhart Zrenner; Marius Ueffing; Francois Paquet-Durand View Presentation 3253 - A0044. Genetic deletion of TLR4 increases retinal ganglion cell survival after optic nerve injury Ying Hu; Ming Yuan; Tian-lin Han; Jingtai Cao; Stanley J. Wiegand; George D. Yancopoulos View Presentation 3254 - A0045. Evaluation of CNTF plus Electrical Stimulation Combined Therapies in the RCS Rat Model of Retinitis Pigmentosa Tracy S. Obertone; Moe H. Aung; Machelle T. Pardue; Vincent T. Ciavatta View Presentation 3255 - A0046. Receptor interacting protein (RIP) kinases-mediated necrosis is involved in photoreceptor degeneration in mice lacking interphotoreceptor retinoid-binding proteins (IRBP) Kota Sato; Songhua Li; Minghao Jin View Presentation 3256 - A0047. Background Data in a Blue Light Model of Retinal Degeneration in the Albino Mouse Kelly Tenneson; Mark Vezina View Presentation 3257 - A0048. Norrin mediates neuroprotective effects on retinal ganglion cells via the induction of leukemia inhibitory factor Andreas Ohlmann; Stephanie Leopold; Roswitha Seitz; Ernst R. Tamm View Presentation 3258 - A0049. Photoreceptor Protection in P23H RHO Transgenic Mice by Systemic Delivery of rAAV.EpoR76E Ana M. de Lucas-Cerrillo; Lauren D'Surney; Tonia S. Rex View Presentation 3259 - A0050. Remote ischemia: effects on retinal function and neuroprotection in a light damage model alice brandli; Sharon Spana; Jonathan Stone View Presentation 3260 - A0051. Neuroprotective Effects of IGF-1 on Retinal Ganglion Cell Survival and Axonal Outgrowth Jie Ma; Chenying Guo; Dong F. Chen; Kameran Lashkari View Presentation 3261 - A0052. VEGF receptor-2 mediated neuro-protection is required for cone photoreceptor survival under hypoxic condition Yun-Zheng Le; Meili Zhu View Presentation 3262 - A0053. Lycium barbarum Extracts Preserve Retinal Function and Reduce Neuronal Damage in a Mouse Model of Transient Retinal Ischemia Di Yang; Da Ma; Raymond Chuen-Chung Chang; Kwok-Fai So; Sai Hung David Wong; Amy C. Lo View Presentation 3263 - A0054. The synaptic clustering protein Vesl-1/Homer 1 mediates protection of retinal neurons Peter Koulen Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 123 sur 222 View Presentation 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 3264 - A0055. Rewiring of photoreceptor cell synapses following rod or cone degeneration in zebrafish Carole Saade; James M. Fadool View Presentation 3265 - A0056. Oral Administration of Picrorrhizae Extract Ameliorates Retina Damage in Rat Optic Nerve Crush Model Yang Qu; Shaodan Zhang; Ruoxi Li View Presentation 3266 - A0057. The Cannabinoid Agonist HU210 Delays Retinal Degeneration and Vision Loss Pedro Lax; Cesare Altavilla; Gema Esquiva; Nicolas Cuenca View Presentation 3267 - A0058. Absence of a functional P2X7 receptor slows photoreceptor degeneration in the rd1 mouse Kirstan A. Vessey; Andrew I. Jobling; Erica L. Fletcher View Presentation 3268 - A0059. Role of Adenosine Kinase in Traumatic Optic Neuropathy Saif Ahmad; Nehal Elsherbiny; Ahmed Elsherbini; Sadanand Fulzele; Gregory I. Liou View Presentation 3269 - A0060. Safety and Efficacy of Retinal Optogenetic Therapy in Canine Models Keirnan Willett; Albert M. Maguire; Jose A. Sahel; Jeannette Bennicelli; Botond Roska ; Serge A. Picaud; Gregory M. Acland; Luk H. Vandenberghe; Jean Bennett View Presentation 3270 - A0061. Serotonin Receptor Modulation and Neuroprotection in Models of Light Damage and Retinal Degeneration Keith V. Michaels; Anastasiya Johnson; Michael J. Gale; Sean P. Davin; Anupam K. Garg; Michael D. Andrews; Hope E. Titus; Mark E. Pennesi View Presentation 3271 - A0062. Intrauterine growth restriction is associated with long-term retinal dysfunction in rats Yves Sauve; Stephane L. Bourque; Sharee Kuny; Sandra Davidge View Presentation 339. AMD: New Drugs, Delivery Systems, and Mechanisms of Action Moderator(s): Maurizio Uva (University of Catania) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM View Session Details 3272 - A0123. Rationale for Treating Wet AMD in Human Using an Oral Pill Consisting of a VEGFR/PDGFR Inhibitor X-82 Chris Liang; David M. Brown; Nauman A. Chaudhry; Michael J. Elman; Jeffrey S. Heier View Presentation 3273 - A0124. A Novel Endogenous Glycan Therapy For Retinal Diseases: Safety, In vitro Stability, Ocular Pharmacokinetics and Bio-distribution Shankar Swaminathan; Huiling Li; Mallika Palamoor; Dorababu Madhura; Bernd Meibohm; Monica M. Jablonski View Presentation 3274 - A0125. A Single 700 µg Dexamethasone Intravitreal Implant (Ozurdex) Effectively Treats Complex Post-Operative Cystoid Macular Edema Daniel F. Kiernan; Glenn Stoller; Ken B. Carnevale; Nina C. Mondoc; Eric Donnenfeld View Presentation 3275 - A0126. Ritonavir Inhibits HIF-1α Mediated VEGF Expression in Retinal Pigment Epithelial Cells Ramya Krishna Vadlapatla; Aswani Dutt Vadlapudi; Dhananjay Pal; Mridul Mukherji; Ashim K. Mitra View Presentation 3276 - A0127. Protection of RPE cells by sulindac against oxidative damage is through ischemic preconditioning (IPC) and involves activation of the peroxisome proliferator activated receptor alpha (PPAR α) Arunodoy Sur; Diane Baronas-Lowell; Manas R. Biswal; Howard M. Prentice; Herbert Weissbach; Janet C. Blanks View Presentation 3277 - A0128. NAT2 STUDY: OMEGA-3 LEVELS IN RED BLOOD CELLS MEMBRANES CORRELATES THE PREVENTIVE EFFECT Eric H. Souied; Cecile Delcourt; Giuseppe Querques; Benedicte Merle; Theodore Smith; Pascale Benlian View Presentation 3278 - A0129. Role of Oil Palm Phenolics in Angiogenesis and Inflammation Souska Zandi; Shintaro Nakao; Dawei Sun; Kenneth Hayes; Farhad Hafezi; Ali HafeziMoghadam View Presentation 3279 - A0130. Bivalent ranibizumab is more active in vitro than bevacizumab Hanieh Khalili; Steve Brocchini; Peng T. Khaw View Presentation 3280 - A0131. Omega-3 long chain polyunsaturated fatty acids promote choroidal neovessel regression Ryoji Yanai; Lama Mulki; Kimio Takeuchi; John H. Sweigard; Jun Suzuki; Philipp Y. Gaissert; Demetrios Vavvas; Wolf-Hagen Schunck; Joan W. Miller; Kip M. Connor View Presentation 3281 - A0132. Preprogrammed Hematopoietic Stem Cells as a Systemic Therapy for Dry AMD Maria B. Grant; Xiaoping Qi; Yuanqing Yan; Lynn C. Shaw; Alfred S. Lewin; Michael E. Boulton View Presentation 3282 - A0133. Structure-Activity Relationship Studies of a Natural Product Inhibitor of Choroidal Angiogenesis Halesha D. Basavarajappa; Bit Lee; Xiang Fei; Carlos Magaña; Catherine Waller; Neil R. Crouch; Dulcie A. Mulholland; Seung-Yong Seo; Timothy W. Corson View Presentation 3283 - A0134. Intravitreal Tanibirumab, a Fully Human Monoclonal Antibody against Vascular Endothelial Growth Factor Receptor 2, Suppresses and Regresses Laserinduced Choroidal Neovascularization in a Rat Model Jaeryung Kim; Sang Ryeol Shim; Sung-Woo Kim; Weon Sup Lee; Jin-San Yoo; Sang Hoon Lee; Sang Jin Kim View Presentation 3284 - A0135. Functional characterization of recombinant anti-VEGF variants in vitro Tobias Wimmer; Birgit Lorenz; Knut Stieger View Presentation 3285 - A0136. Long-term efficacy of ciliary muscle gene transfer of three sFlt-1 variants in a rat model of laser-induced choroidal neovascularization Mohamed El Sanharawi; Elodie Touchard; Romain Benard; Pascal Bigey; Virginie Escriou; Chadi Mehanna; Marie-Chritine Naud; Jean-Claude P. Jeanny; Marianne Berdugo Polak ; Francine F. Behar-Cohen View Presentation 3286 - A0137. Immune-Like Complexes of Bevacizumab Bind to Retinal Pigment Epithelial Cells and Endothelial Cells in vitro Yang Liu; Terra B. Potocky; Jingtai Cao; Joel Martin; Nicholas Papadopoulos; Stanley J. Wiegand View Presentation 3287 - A0138. A Mechanism-Based Binding Model for the Pharmacokinetics and Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 124 sur 222 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM Pharmacodynamics (PK-PD) of RN6G (PF-04382923), a Humanized Monoclonal Antibody against Amyloid β Peptides, in Subjects with Dry, Age-Related Macular Degeneration Including Geographic Atrophy Kai H. Liao; Pamela D. Garzone; Sangeetha S. Bollini; Philip M. Fanning; Gilbert Wong; Xu Meng View Presentation 3288 - A0139. Short Term Effect of Intravitreal Aflibercept Injection In IntraOuclar Pressure Kasra Attaran-Rezaei; Carmel Moazez; Clive H. Sell; Alan J. Gordon; Rahul Reddy; Henry M. Kwong; Stephen De Souza; Matthew C. Ziemianski; Belinda Shirkey; Shepard Bryan View Presentation 3289 - A0140. In vivo imaging of fluorescent probes linked to antibodies against human and rat vascular endothelial growth factor (VEGF) Johanna Meyer; Alexander Cunea; Pia Welker; Kai Licha; Dagmar Sonntag-Bensch; Steffen Schmitz-Valckenberg; Frank G. Holz View Presentation 3290 - A0141. Generation of Combination PDGF / VEGF-antagonist ECT devices Vincent Ling; Arne Nystuen; Susan A. Elliott; Lisa Orecchio; Brenda Dean; Konrad Kauper; Weng Tao View Presentation 3291 - A0142. MORPHOLOGICAL STUDY OF THE GANGLION CELL LAYER OF RABBITS AFTER INTRAVITREAL INJECTION OF MYCOPHENOLIC ACID Andre M. Liber; Rafael M. Ferraro; Dora F. Ventura; Francisco Max Damico; Christina Joselevitch View Presentation 3292 - A0143. Development and Characterization of a 3-Dimensional Human Corneal Full Thickness Tissue Model Yulia Kaluzhny; Laurence d’Argembeau-Thornton; Helena Kandarova; Pat Hayden; Mitch Klausner View Presentation 3293 - A0144. Nutritional supplementation for age related macular degeneration in Italy Ilaria Zucchiatti; Maurizio B. Parodi; maria vittoria cicinelli; Maria Lucia Cascavilla; Francesco Fasce; Matteo Prati; Francesco Bandello View Presentation 3294 - A0145. Feasibility of Cryopreservation of the Encapsulated Cell Technology Devices Cahil McGovern; John D. Duggan; Crystal Cortellessa; Sandy Sherman; Melissa Stiles; Konrad Kauper; Allyse Mazzarelli; Weng Tao View Presentation 3295 - A0146. Continuous Intraocular Drug Delivery over 5 ½ Years: Ciliary Neurotrophic Factor (CNTF)Production by Encapsulated Cell Technology Implants Treating Patients with Retinitis Pigmentosa and Geographic Atrophy Konrad Kauper; Cahil McGovern; Paul Stabila; Sandy Sherman; Pam Heatherton; Brenda Dean; Crystal Cortellessa; Alice Lee; Weng Tao View Presentation 3296 - A0147. Effect of Apolipoprotein A1-mimetic peptides on cell viability of cultured retinal pigment epithelial cells Yoko Miura; Ingrid Fritz; Salvatore Grisanti; Martin Rudolf View Presentation 3297 - A0148. Beta cyclodextrins bind and remove Lipofuscin Bisretinoids from RPE Marcelo M. Nociari View Presentation 3298 - A0149. Safety of implantation of the NT-503 device in patients with Choroidal Neovascularization secondary to Age-related Macular Degeneration Jose Luis Guerrero-Naranjo; Hugo Quiroz-Mercado; Gustavo Sanchez-Bermudez; Fernando Schoonewolff; Samantha Salinas Longoria; Rafael Romero Vera; Weng Tao; Richard L. Beckman; Virgilio Morales-Canton View Presentation 3299 - A0150. Suprachoroidal Microinjection of Bevacizumab is Well Tolerated in Human Patients Virgilio Morales-Canton; Jans J. Fromow-Guerra; Samantha Salinas Longoria; Rafael Romero Vera; Michelle Widmann; Samirkumar R. Patel; Benjamin Yerxa View Presentation 340. Vitreoretinal Surgery II Moderator(s): Baruch Kuppermann (University of California Irvine) and Vinit Mahajan (University of Iowa) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM View Session Details 3300 - B0188. Amber Filter vs Conventional Xenon Light source for 23 Gauge pars plana vitrectomy in epiretinal membrane: OCT and Autofluorescence findings Michele Coppola; Mirella Lizzano; Sylvia Marchi View Presentation 3301 - B0189. Pars plana vitrectomy with medium-term perfluoro-n-octane (PFO) for severe proliferative diabetic retinopathy (PDR) with traction retinal detachment (TRD) Carmen L. Gonzalez; Ramanath Bhandari; Shulamit Schwartz; Naresh Mandava; Jeffrey Olson; Scott Oliver; Virgilio Morales-Canton; Marc Mathias; Hugo Quiroz-Mercado View Presentation 3302 - B0190. Anatomical and functional outcomes of macular hole surgery in a single VR unit (2005-2012) Robert Johnston; Javier Zarranz-Ventura; Ahmed Sallam; Dawn A. Sim; Pearse A. Keane; Nigel Kirkpatrick View Presentation 3303 - B0191. Vitreoretinal Surgical Outcomes Performed by Supervised Retinal Fellows Versus Attending Faculty Surgeons John O. Mason; John O. Mason; Gerald McGwin; Lauren B. Mason; Thomas A. Finley; Duncan A. Friedman; Dustin Pomerleau; Michael A. Albert; Richard M. Feist; Martin L. Thomley View Presentation 3304 - B0192. Functional and Anatomical Outcomes of Tissue Plasminogen Activator (tPA) Treatment for Submacular Hemorrhage Associated with Exudative Macular Degeneration (ExAMD): A Comparative Analysis Between Intra-vitreal and Sub-retinal tPA injected Patients Mark Sherman; Shlomit Schaal; Charles C. Barr View Presentation 3305 - B0193. Erbium:YAG Laser Scalpel with Novel Microsphere Chain Fiber Optic Tip for More Precise Vitreoretinal Surgery Howard S. Ying; Andrew N. Antoszyk; Thomas Hutchens; Arash Darafsheh; Amir Fardad; Nathaniel M. Fried; Vasily N. Astratov View Presentation 3306 - B0194. Quantitative proteomics of vitreous humor to identify potential markers involved in the induction of posterior vitreous detachment Ravi Keshavamurthy; Jin Koh; Sixue Chen; K V Chalam View Presentation 3307 - B0195. Fog formation on intraocular lenses during vitrectomy: Effect of Perfluorocarbon Liquids Joshua D. Udoetuk; Faryar Tavakoli; Jasmine Verret; Anisha Keshavan; Pirouz Kavehpour; Jean-Pierre Hubschman View Presentation 3308 - B0196. Impact of Surgical Peeling on Retinal Microarchitecture in Epiretinal Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 125 sur 222 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM Membrane Surgery Visualized with Intraoperative Optical Coherence Tomography Justis P. Ehlers; Bryan Roth; Peter K. Kaiser; Rishi Singh; Sunil K. Srivastava View Presentation 3309 - B0197. Analysis of a Blend of Poly(acryamide) Gels with Varying Sodium Acrylate Formulations for Use in Vitreous Hydrogel Substitutes Paul D. Hamilton; Nisha Iyer; Nathan Ravi View Presentation 3310 - B0198. Correlation of anesthetic medications with required airway interventions during retrobulbar anesthesia Lingmin He; Jody C. Leng; Ruwan A. Silva; Theodore Leng View Presentation 3311 - B0199. Characteristics of epiretinal membranes which influence post-surgical visual outcomes Sahar Bedrood; Linda A. Lam; Srinivas Sadda View Presentation 3312 - B0200. Blue Perfluoro-n-Octane and Blue Perfluorodecaline Stability and Residue Testing Fabio M. Trindade; Jose Garcia-Arumi View Presentation 3313 - B0201. Relation between retinal vessel printings and visual acuity in patients with macular epiretinal membranes Roberto dell'Omo; Francesco Cifariello; Mariluccia Cassetta; Di Salvatore Angela; Antonio De Lena; Mariaelena Filippelli; Ermanno dell'Omo; Ciro Costagliola View Presentation 3314 - B0202. Two-year Results of AcrySof Toric Intraocular Lens Implantation in Patients with Combined Microincision Vitrectomy Surgery and Phacoemulsification Dong Ho Park; Jin Young Lee; Jae Pil Shin; In Taek Kim View Presentation 3315 - B0203. Retinal Unfolding after Vitrectomi for Idiopathic Macular Pucker Mads Kofod; Morten D. de La Cour View Presentation 3316 - B0204. Clouding of intraocular silicone oil in the absence of emulsification Martin S. Spitzer; Jan Willem de Vries; Andreas Herrmann; Karl-Ulrich Bartz-Schmidt; Sascha Dammeier View Presentation 3317 - B0205. 25-gauge Vitrectomy For Macular Holes With And Without Retinal Detachment In Highly Myopic Eyes Francesco Boscia; Nicola Recchimurzo; Luigi Sborgia; Ermete Giancipoli; Claudio Furino View Presentation 3318 - B0206. Robot-assisted vitreoretinal surgery Mathias M. Maier; M. Ali Nasseri; Daniel M. Zapp; Martin Eder; Karin Kobuch; Chris P. Lohmann; Alois Knoll View Presentation 3319 - B0207. Macular hole formation after vitrectomy ; Preventable? Rebecca Kim; Yu Cheol Kim; Kwang-Soo Kim View Presentation 3320 - B0208. Surgical outcomes of idiopathic epiretinal membrane with good visual acuity Sung Il Kim; Seung ho Cho; Sung Who Park; Ik Soo Byon; Jaeho Jung; Ji-Eun Lee; Ji Eun E. Lee View Presentation 3321 - B0209. Mechanical Properties of Vitreous Humor in Eye Pairs Pirouz Kavehpour; Ryan Freeman; Rommina Vedadghavami; Sanket U. Shah; Rouzbeh Amini; Jean-Pierre Hubschman View Presentation 3322 - B0210. The impact of hospital admission on systemic adverse outcomes after pediatric vitreoretinal surgery Richard Y. Hwang; Ajay Shalwala; Ariana K. Tabing; Stephen J. Kim View Presentation 3323 - B0211. Surgical Outcomes of 25-Gauge Vitrectomy for Diabetic Tractional Retinal Detachment Kevin Patel; Mark S. Dikopf; Vikram Setlur; Jennifer I. Lim View Presentation 3324 - B0212. Visual Acuity Outcomes in Patients Undergoing Epiretinal Membrane (ERM) and Internal Limiting Membrane (ILM) Peel With and Without Intraoperative Intraocular Triamcinolone Shawn Agee; Robert Wang; Richard Winslow View Presentation 3325 - B0213. Complications in Heavy Silicone Oil Surgery Hendrik Schwarzer; Babac A. Mazinani; Niklas Plange; Peter Walter; Gernot Roessler View Presentation 3326 - B0214. Speed of silicone oil removal through common cannulas David Cupp; Colin A. McCannel View Presentation 3327 - B0215. The influence of vitrectomy machine fluidics on the rate of iatrogenic retinal breaks in primary small-gauge vitrectomies Renaud Duval; John S. Pollack; Joseph M. Civantos; Kirk H. Packo View Presentation 3328 - B0216. Visual Acuity and Anatomic Outcomes Following Surgery for Myopic Macular Retinoschisis Jonathan S. Chang; Anita R. Shane; Michael Engelbert; William E. Smiddy; Stanley Chang; Harry W. Flynn View Presentation 3329 - B0217. Comparison of fundus-viewing quality using wide-field observation system through various intraocular lenses Haruhiko Yamada View Presentation 3330 - B0218. A new 25G back flush needle Shumpei Obata; Kenji Someya; Masashi Kakinoki; Masahito Ohji View Presentation 3331 - B0219. Ex-vivo evaluation of thermosensitive hydrogels as vitreous substitutes Sabrina M. Bohnacker; Nadine Hagedorn; Stefan Kamlage; Wilfried Kugler; Andreas Lendlein; Mathias M. Maier; Axel T. Neffe; Arthur Messner; Chris Lohmann; Karin Kobuch View Presentation 3332 - B0220. Serum protein analysis of patients with different vitreoretinal diseases by means of antibody microarrays Christina A. Korb; Sabine Beck; Katrin Lorenz; Alireza Mirshahi; Bernhard Stoffelns; Norbert Pfeiffer; Franz H. Grus View Presentation 3333 - B0221. Outcomes of Idiopathic Macular Hole Surgery Janet Manalac; John Frisbee; D Anthony Mazzulla View Presentation 3334 - B0222. Inner Retinal Dimples Occur Following Inner Limiting Membrane Peeling Without Staining Franck Amouyal; Carolyn K. Pan; Steven D. Schwartz; Jean-Pierre Hubschman View Presentation 3335 - B0223. 23-Gauge Transconjunctival Sutureless Pars Plana Vitrectomy In Different Posterior Segment Diseases. Complications, Visual Outcomes And Results: An Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 126 sur 222 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM Update Marcelo Zas; Carina P. Rinaudo; Lucas Adamo; Gaston Gomez Caride; Pablo Chiaradia View Presentation 3336 - B0224. Effects of Ozurdex on Persistent Macular Edema After Vitrectomy with Membrane Peeling John Khadem; Shayan Khorsandzadeh; Jane Pan; Cristiana Pieroni View Presentation 3337 - B0225. Macular function in patients with macular pucker treated with 23 gauge vitrectomy Giancarlo Dell'Aversana Orabona; Angelo Rampone; Luigi Di Perna; Francesco Testa; Settimio Rossi; Michele Della Corte; Francesca Simonelli View Presentation 3338 - B0226. Association of Retinal Sensitivity and Morphology in epiretinal membranes before and after vitrectomy Patricia Udaondo; Ana Hervás Ontiveros; Salvador Garcia-Delpech; David Salom ; Sebastian Martinez-Castillo; Manuel Díaz-Llopis View Presentation 3339 - B0227. Vitrectomy with Intentional Bullous Retinal Detachment to Mobilize and Move Recent Subfoveal Hemorrhage in Age-related Macular Degeneration Deepthi Reddy; Matthew H. Oltmanns; Mathew R. Sapp; Robert E. Morris View Presentation 3340 - B0228. Morphological Change of Inner Retinal Layer on Spectral Domain Optical Coherence Tomography following Macular Hole Surgery Hyung-Woo Kwak; Kook Young Kim; TaeGi Kim; Kyung Hoon Seo; Seung-Young Yu View Presentation 3341 - B0229. Triamcinolone Acetonide (TA) Assisted Removal of Internal Limiting Membrane (ILM) Homayoun Tabandeh; David S. Boyer; David Liao View Presentation 3342 - B0230. vitrectomy outcomes for diabetic vitreous hemorrhage Gaston Gomez Caride; leonardo ferlini; Luciano Perrone; gerardo valvecchia; Marcelo Zas View Presentation 3343 - B0231. Perioperative Intravitreal Bevacizumab: When to Inject It to Be Friend not Foe? Narcisa Ianopol View Presentation 3344 - B0232. 12 Month Follow-up of Epiretinal Membranectomy David S. Dyer; William Anderson; Michael P. Ellis View Presentation 341. Exome Sequencing: New Genes, Methods and Databases Moderator(s): Terry Braun (University of Iowa) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM View Session Details 3345 - C0001. Exome sequencing identifies RDH12 gene compound heterozygous mutations in a Mexican inbred family with severe autosomal recessive retinitis pigmentosa Juan C. Zenteno; Oscar F. Chacon-Camacho; Beatriz Buentello; Serguei Jitskii View Presentation 3346 - C0002. Exome sequencing identifies mutations of both MYO7A and PDE6B in three siblings with retinitis pigmentosa Tamar Ben-Yosef; Nitza Goldenberg-Cohen; Eyal Banin; Ben Cohen; Yael Zalzstein; Leah Rizel; Lina Basel-Vanagaite View Presentation 3347 - C0003. Exome analysis identified novel mutations in the FAM161A gene in a family with recessive retinal degeneration Jacque L. Duncan; Pooja Biswas; Igor Kozak; Mili Navani; Rafael C. Caruso; John R. Heckenlively; Austin Roorda; Radha Ayyagari View Presentation 3348 - C0004. Whole Exome Sequencing as a Tool for Identification of Genes Causing Autosomal Recessive Retinitis Pigmentosa Dror Sharon; Lina Zelinger; Samer Khateb; Avigail Beryozkin; Liliana MizrahiMeissonnier; Samuel G. Jacobson; Eyal Banin View Presentation 3349 - C0005. Identification of causative mutations in consanguineous pedigrees from Pakistan with recessive retinal degeneration by whole exome analysis Pooja Biswas; Bruno Maranhao; Pauline Lee; John Suk; Mili Navani; Shahid Y. Khan; Nadeem H. Butt; Sheikh Riazuddin; S. Amer Riazuddin; Radha Ayyagari View Presentation 3350 - C0006. Whole exome sequencing identifies mutations in LRIT3 as a cause for autosomal recessive complete congenital stationary night blindness Christina Zeitz; Samuel G. Jacobson; Christian P. Hamel; Kinga M. Bujakowska; Marion Neuillé; Elise Orhan; Xavier Zanlonghi; Jose A. Sahel; Shomi S. Bhattacharya; Isabelle S. Audo View Presentation 3351 - C0007. A Missesne Mutation in the Acetyl-CoA Carboxylase β Gene Involved in Lipid Metabolism is Associated with Autosomal Recessive Retinitis Pigmentosa Lina Zelinger; Carmen Ayuso; Eyal Banin; Dror Sharon View Presentation 3352 - C0008. RP1L1 variants are associated with retinitis pigmentosa and occult macular dystrophy Panagiotis I. Sergouniotis; Alice E. Davidson; Donna S. Mackay; Genevieve A. Wright; Michel Michaelides; Graham E. Holder; Anthony G. Robson; Anthony T. Moore; Vincent Plagnol; Andrew R. Webster View Presentation 3353 - C0009. RNA-Seq Approach for the Refinement of a Modifier Locus in a Canine Model of Cone-Rod Dystrophy Keiko Miyadera; Matthew Brooks; Gautami Das; Anand Swaroop; Gustavo D. Aguirre View Presentation 3354 - C0010. Exome sequencing in dogs with progressive retinal atrophy to facilitate the development of therapeutic intervention studies Rob W. Collin; Arjen Henkes; Galuh D. Astuti; Christian Gilissen; Birgit Lorenz; Alexander Hoischen; Frans P. Cremers; Knut Stieger View Presentation 3355 - C0011. Exome Sequencing Identifies a Novel RP1 Mutation in a Belgian Family with Autosomal Dominant Retinitis Pigmentosa Caroline Van Cauwenbergh; Frauke Coppieters; Sarah De Jaegere; Julie De Zaeytijd; Bart P. Leroy; Elfride De Baere View Presentation 3356 - C0012. The familial dementia gene revisited: ITM2B missense mutation causes a new dominant retinal dystrophy Isabelle S. Audo; Kinga M. Bujakowska; Elise Orhan; Florian Sennlaub; Xavier P. Guillonneau; Thierry D. Leveillard; Saddek Mohand-Said; Shomi S. Bhattacharya; Jose A. Sahel; Christina Zeitz View Presentation 3357 - C0013. Variant prioritization and linkage mapping using whole-exome sequencing data for families with autosomal dominant retinitis pigmentosa (adRP) Daniel C. Koboldt; David E. Larson; Lori S. Sullivan; Sara J. Bowne; Robert S. Fulton; Erica Sodergren; Susan H. Blanton; Stephen P. Daiger; Richard K. Wilson; George M. Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 127 sur 222 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM Weinstock View Presentation 3358 - C0014. Whole-exome sequencing in age-related macular degeneration Margaret A. Pericak-Vance; Gaofeng Wang; William Cade; Monique D. Courtenay; Patrice Gay; Stephen G. Schwartz; Jaclyn L. Kovach; Anita Agarwal; Jonathan L. Haines; William K. Scott View Presentation 3359 - C0015. Mutation analysis of B3GALTL in Peters Plus Syndrome and alike phenotypes Eric Weh; Linda M. Reis; Rebecca C. Tyler; Elena V. Semina View Presentation 3360 - C0016. Next Generation Sequencing Reveals A Novel Gene Mutation in Primary Congenital Glaucoma Patients Terri L. Young; Sing H. Lim; Tammy Yanovitch; Thomas P. Klemm; Elizabeth St.Germain; Sebastian Maurer-Stroh; Vachiranee Limviphuvadh; Nicholas Katsanis; Steve Rozen; Khanh-Nhat Tran-Viet View Presentation 3361 - C0017. CCDC111 mutation was identified in high myopia through exome sequencing Fuxin Zhao; Xiangtian Zhou; Anquan Xue; Yanfeng Su; Jia Qu View Presentation 3362 - C0018. The superior ocular fissure: a novel finding in early eye development Tara Stach; Jakub Famulski; Andrew Waskiewicz; Ordan J. Lehmann View Presentation 3363 - C0019. ALDH1A3 mutations cause recessive anophthalmia and microphthalmia Lucas Fares Taie; Sylvie Gerber; Nicolas Chassaing; Jill Clayton-Smith; Eduardo D. Silva; Arnold Munnich; Patrick Calvas; Josseline Kaplan; Nicola Ragge; Jean-Michel Rozet View Presentation 3364 - C0020. Whole exome sequencing identifies novel mutations in OTX2 , CRYBA4, and PAX6 in microphthalmia patients Brett Deml; Linda M. Reis; Elena V. Semina View Presentation 3365 - C0021. Exome Sequencing Identification of a Novel Causal Mutation for Eyelid Dysplasia Elizabeth St.Germain; Khanh-Nhat Tran-Viet; Thomas P. Klemm; Vachiranee Limviphuvadh; Sebastian Maurer-Stroh; Nicholas Katsanis; Yasmin Shayesteh; James Katowitz; Steve Rozen; Terri L. Young View Presentation 3366 - C0022. Identification of Mutations in Candidate Genes in Patients with Globe Anomalies: A Targeted Next-Generation Sequencing Approach Sushil K. Dubey; Perumalsamy Vijayalakshmi; Sharwan K. Kedia; Periasamy Sundaresan View Presentation 3367 - C0023. Whole Exome Sequencing (WES) indentifies a mutation in ALPK1 responsible for a novel, autosomal dominant disorder of vision loss, splenomegaly, and pancytopenia Lloyd B. Williams; Chad D. Huff; Denise Morgan; Rosann Robinson; Margaux A. Morrison; Krista Kinard; George Rodgers; Kathleen B. Digre; Margaret M. DeAngelis View Presentation 3368 - C0024. Genetic diagnostic testing in a large cohort of retinitis pigmentosa patients using panel-based next generation sequencing Julia Mohr; Nicola Gloeckle; Susanne Kohl; Tim Scheurenbrand; Andrea Sprecher; Antje S. Bernd; Eberhart Zrenner; Bernd Wissinger; Konstanze Hörtnagel View Presentation 3369 - C0025. Highly efficient genetic diagnostic testing in patients with inherited retinal dystrophies using Panel-based Next Generation Sequencing Nicola Gloeckle; Susanne Kohl; Julia Mohr; Tim Scheurenbrand; Andrea Sprecher; Saskia Biskup; Wolfgang Berger; Bernd Wissinger; John Neidhardt View Presentation 3370 - C0026. Inherited eye disease gene chip study Liping Yang View Presentation 3371 - C0027. Carriers of degenerative retinal diseases can be easily identified using target capture next generation sequencing Shirel R. Weiss; Eran Eyal; Mali Salmon-Divon; Yoram Cohen; Nitza Goldenberg-Cohen View Presentation 3372 - C0028. A dual approach for comprehensive genetic testing of ABCA4 in Stargardt disease Miriam Bauwens; Caroline Van Cauwenbergh; Sarah De Jaegere; Steve Lefever; Barbara D'haene; Filip Pattyn; Bart P. Leroy; Elfride De Baere; Frauke Coppieters View Presentation 3373 - C0029. High-coverage next-generation sequencing (NGS) for retinal dystrophies and Usher syndrome: High diagnostic yield, CNV detection, novel disease mechanisms and therapy targets Hanno J. Bolz; Christine Neuhaus; Markus N. Preising; Arif O. Khan; Martin Gliem; Peter Charbel Issa; Uwe Wolfrum; Andreas Gal; Birgit Lorenz; Tobias Eisenberger View Presentation 3374 - C0030. A Comparison of Two Commercially Available Genetic Tests for AgeRelated Macular Degeneration Nancy M. Holekamp; Mathew MacCumber; Arghavan Almony View Presentation 3375 - C0031. Evaluation of Genetic Testing Outcomes for a 4-year Interval of Service Provided to Southwest Eye Registry Participants Kaylie D. Webb; Dianna K. Wheaton View Presentation 3376 - C0032. Positive and Unlabeled Learning for Prioritizing Candidate Variants in Retinal Degenerative Diseases Alex H. Wagner; Kyle Taylor; Adam P. DeLuca; Thomas Casavant; Edwin M. Stone; Robert F. Mullins; Todd E. Scheetz; Terry A. Braun View Presentation 3377 - C0033. A whole exome variant filtering software for identification of disease causing variants Bruno Maranhao; Pooja Biswas; Gabriel A. Silva; John R. Heckenlively; S. Amer Riazuddin; Pauline Lee; Radha Ayyagari View Presentation 3378 - C0034. Detection of sample contamination in clinical next-generation sequencing Todd E. Scheetz; Adam P. DeLuca; Edwin M. Stone; Terry A. Braun View Presentation 3379 - C0035. Towards Comprehensive Registration of DNA Sequence Variants Associated with Inherited Retinal Diseases in Leiden Open Variation Databases Frans P. Cremers; Johan T. den Dunnen; Muhammad Ajmal; Alamdar Hussain; Muhammad I. Khan; Markus N. Preising; Stephen P. Daiger; Raheel Qamar View Presentation 3380 - C0036. Challenges of Microbiome Research on the Ocular Surface Diane L. Smith; Suzanne Kennedy; Richard A. Gibbs; Dan B. Jones; Cintia S. De Paiva; Stephen C. Pflugfelder; Joseph F. Petrosino View Presentation 3381 - C0037. Utilizing Golden Helix SVS Software to Facilitate in the Identification of Genes for Ocular Diseases Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 128 sur 222 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM Khanh-Nhat Tran-Viet; Elizabeth St.Germain; Greta L. Peterson; Autumn Laughbaum; Vincent J. Soler; Tammy Yanovitch; Steve Rozen; Terri L. Young View Presentation 3382 - C0038. Vision Variation Database (VVD) Adam P. DeLuca; Sean Ephraim; Todd E. Scheetz; Edwin M. Stone; Terry A. Braun View Presentation 3383 - C0039. The Ocular Tissue Database Terry A. Braun; Alex H. Wagner; Adam P. DeLuca; Thomas Casavant; Todd E. Scheetz; Abbot F. Clark; Robert F. Mullins; Edwin M. Stone View Presentation 342. Ganglion Cells, Visual Brain and Behavior Moderator(s): Tiffany Schmidt (Johns Hopkins University) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM View Session Details Include in Itinerary Include in Itinerary Include All in Itinerary 3384 - C0105. TRPM3 expression in the mouse retina Robert M. Duvoisin; Wei-Hong Xiong; Brian T. Reed; Catherine W. Morgans; R L. Brown View Presentation 3385 - C0106. VEGF-R1 activation increases survival of purified retinal ganglion cells Nicolas G. Froger; Valérie Forster; Dorothée Pain; Ivana Ivkovic; Nadège Brunel; Jose A. Sahel; Serge A. Picaud View Presentation 3386 - C0107. Changes in retinal ganglion cell activity in the P23H mini-swine model of retinal degeneration Juan P. Fernandez de Castro; James Demas; James W. Fransen; Paul J. DeMarco; Henry J. Kaplan; Maureen A. McCall View Presentation 3387 - C0108. Toward a complete functional classification of ganglion cells in the rat retina Sneha Ravi; Daniel Ahn; Martin Greschner; Alan M. Litke; E. J. Chichilnisky; Greg D. Field View Presentation 3388 - C0109. Functional Classification of Mouse Retinal Ganglion Cells Erin Zampaglione; Arash Ng; Jennifer Roebber; David Feldheim; Alexander Sher View Presentation 3389 - C0110. Cre-expressing retinal ganglion cells in a Pcp2-Cre transgenic mouse Ching-Kang J. Chen; Yin-Peng Chen; Hung-Ya Tu; Viet Chau; Adam R. McQuiston; Chuan-Chin Chiao View Presentation 3390 - C0111. Gap-junctions between Populations of Ganglion and Amacrine Cells in the Mouse Retina Ji-Jie Pang; David Paul; Samuel M. Wu View Presentation 3391 - C0112. Dynamic interactions between rod and cone signaling pathways in the inner retina William Grimes; Fred Rieke View Presentation 3392 - C0113. A Non-Conventional Circuit Mechanism for the Center-Surround Receptive Field of a Retinal Ganglion Cell Jan Homann; Michael A. Freed View Presentation 3393 - C0114. Synaptic pathways underlying spatial, contrast and temporal tuning of parasol-Y ganglion cells in primate retina Joanna Crook; Orin S. Packer; Dennis M. Dacey View Presentation 3394 - C0115. ON-OFF DS Ganglion Cells Detect Motion and Suppress Luminance Responses During Natural Viewing Maesoon Im; Shelley I. Fried View Presentation 3395 - C0116. Contextual Phase Tuning of Synaptic Inputs to Direction-selective Ganglion Cells Ya-Chien Chan; Seunghoon Lee; Chuan-Chin Chiao; Z Jimmy Zhou View Presentation 3396 - C0117. Spike correlations and direction encoding in the retina Maxwell Turner; Joel Zylberberg; Jon Cafaro; Eric Shea-Brown; Fred Rieke View Presentation 3397 - C0118. Origin of the Subunit Nonlinearity in Retinal Ganglion Cell Receptive Fields Bart G. Borghuis; Loren L. Looger; Jonathan B. Demb View Presentation 3398 - C0119. Feed-forward Inhibition Controls Spike Onset Latency in Rabbit Local Edge Detectors Ilya Buldyrev; William R. Taylor View Presentation 3399 - C0120. Optimal waveform parameters for extracellular activation of RGCs Alex E. Hadjinicolaou; Craig O. Savage; David J. Garrett; Nicholas V. Apollo; Shaun L. Cloherty; Michael R. Ibbotson; Brendan J. O'Brien View Presentation 3400 - C0121. Attention enhances the Pupillary Light Reflex Paola Binda; Maria Pereverzeva; Scott O. Murray View Presentation 3401 - C0122. Monocular Visual Acuity Measurement in Adult bugeye Zebrafish Using Optokinetic Response Faydim Rassamdana; Kathleen Dang ; D Joshua Cameron View Presentation 3402 - C0123. Functional changes and differential distribution of the NMDA receptors in rd 10 mice Abduqodir Toychiev; Elena Ivanova; Christopher Yee; Botir T. Sagdullaev View Presentation 3403 - C0124. Spatial Distribution of Excitatory Synapses in Mouse Retinal Ganglion Cells Chuan-Chin Chiao; Yin-Peng Chen View Presentation 3404 - C0125. Role of the NMDA receptor coagonist D-serine in retinal function measured with the optokinetic reflex Manuel Esguerra; Amy L. Silberschmidt; Robert F. Miller View Presentation 3405 - C0126. Regulated NMDA signaling in transient and sustained pathways Santhosh Sethuramanujam; Malcolm Slaughter View Presentation 3406 - C0127. Synthetic conantokin peptides potently inhibit NMDA receptor-mediated currents of retinal ganglion cells Luoxiu Huang; Dao-Qi Zhang; Francis J. Castellino View Presentation Include in Itinerary 3407 - C0128. Assessment of Ca2+-permeable AMPA receptor calcium dynamics in ganglion cell layer neurons in an animal model of ocular hypertension Elizabeth Cairns; Michele L. Archibald; Balwantray C. Chauhan; Melanie E. Kelly; William H. Baldridge View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 129 sur 222 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 3408 - C0129. Analysis of retinal ganglion cells projecting to the koniocellular superficial (K1) layer of the lateral geniculate nucleus in marmoset monkey Kumiko A. Percival; Paul R. Martin; Ulrike Grunert View Presentation 3409 - C0130. Principal components analysis (PCA) of human cortical contrast response functions reveals two dominant mechanisms: M and P? Russell D. Hamer; Givago S. Souza; Thiago L. Costa; Bruno D. Gomes; Luiz Carlos L. Silveira; Dora F. Ventura View Presentation 3410 - C0131. The Awake Rabbit as a Model For Studies of Transcranial Direct Current Stimulation of The Visual Cortex Thiago L. Costa; Claudia Ammann; Gabriela L. Ioshimoto; Agnès Gruart; José M. Delgado-García; Dora F. Ventura; Javier Márquez-Ruiz View Presentation 3411 - C0132. High-Throughput Visual Acuity Device for Rats: Training and Development Jeffrey A. Jamison; Scott Baron; Thomas S. Vihtelic View Presentation 3412 - C0133. The Relationship of Specific Categorical Variables with PET Scan White Matter Activation in Blind and Control Subjects Using BrainPort Julie M. Steinbrink; Charles Laymon; Bedda L. Rosario; Amy C. Nau View Presentation 3413 - C0134. Size-invariant shape coding in visual area V4 Yasmine El-Shamayleh; Anitha Pasupathy View Presentation 3414 - C0135. Imagery of a Face Enhances Event-Related Potentials to Ambiguous Visual Stimuli Lingxi Lu; Yonghong Tian; Tiejun Huang; Xihong Wu; Wen Gao; Liang Li View Presentation 343. Circadian and Adaptational Modulation Moderator(s): Christophe Ribelayga (UTHealth - UT Med School at Houston) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM View Session Details 3415 - C0136. Retinal CLOCK and NPAS2: Differential Expression, Circadian Gene Regulation, and Roles in Visual Function Christopher K. Hwang; P M. Iuvone View Presentation 3416 - C0137. On-Off Direction-Selective Retinal Ganglion Cells Co-Express CART and NPAS2, a Circadian Clock Protein S. Anna Sargsyan; Christopher K. Hwang; P M. Iuvone View Presentation 3417 - C0138. Light-dark Condition Regulates Sirtuin Genes in the Retina Norimitsu Ban; Takaaki Inaba; Seiji Miyake; Kazuo Tsubota; Yoko Ozawa View Presentation 3418 - C0139. Diurnal Effects on Pupil Size of Unrestrained WT Mice and Mice Lacking Rod - or Cone Function Franklin Naarendorp; Curtis Van Slyck View Presentation 3419 - C0140. Circadian rhythm of electroretinograms in living zebrafish larvae Hisashi Matsubara; Toshio Tanaka; Yuhei Nishimura; Yoshitsugu Matsui; Tetsuro Yamamoto; Mineo Kondo View Presentation 3420 - C0141. Turnover rate of the neuronal connexin Cx36 in HeLa cells Yanran Wang; John O'Brien View Presentation 3421 - C0142. Dopamine differentially affects network light adaptation in ON- and OFFcenter transient retinal ganglion cells Michael L. Risner; Chad R. Jackson; Douglas McMahon View Presentation 3422 - C0143. Light adaptation alters the spatial distribution of inhibition to the retinal OFF pathway Reece Mazade; Erika D. Eggers View Presentation 3423 - C0144. Photoperiod Dependence of the Mouse Retinal Dopaminergic System Zhijing Zhang; Grant C. Hopping; Xiaoqin Liu; Christophe Ribelayga View Presentation 3424 - C0145. Investigating circadian rhythms in mouse retinal dopaminergic amacrine neurons heng dai; Douglas McMahon View Presentation 3425 - C0146. Seeking For Circadian Rhythmicity in the Mammalian Photoreceptor Visual Cycle Yunlu Xue; Vladimir J. Kefalov View Presentation 3426 - C0147. Optic nerve involvement in relation to rest-activity circadian rhythm in Alzheimer's disease Chiara La Morgia; Roberto Gallassi; Luisa Sambati; Federica Provini; Piero Barboni; Valerio Carelli View Presentation 3427 - C0148. Die Fledermaus: In Retinal Light-Adaptation, Chicks Are Mice With Wings Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Qing Shi; William K. Stell View Presentation 344. Cones and Outer Retina Moderator(s): Nathan Doble (New England College of Optometry) and Adam Boretsky (Univ of Texas Medical Branch) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM View Session Details 3428 - C0149. Photoreceptor Pointing as a Function of Retinal Eccentricity in Normal Human Eyes Nathan Doble; Rebecca Kivlin; Johanan L. Codona; Simone Li; Stacey S. Choi View Presentation 3429 - C0150. The role of defocus on photoreceptor light coupling analyzed with a waveguide-based retinal simulator Brian Vohnsen; Diego Rativa Millan; Carmen Vela; Benjamin Lochocki; Philip B. Kruger View Presentation 3430 - C0151. Measurement of the Photoreceptor Pointing in the Living Chick Eye Maria Walker; Rebecca Kivlin; Nathan Doble View Presentation 3431 - C0152. Reproducibility of the rtx1 adaptive optics retinal camera Dirk-Uwe G. Bartsch; Cheryl Arcinue; Feiyan Ma; Lingyun Cheng; William Freeman View Presentation 3432 - C0153. Test-Retest Reliability of Microperimetry Using the Optos OCT SLO in Eyes With and Without Known Retinal Diseases Hyun Soo Jang; Yasir J. Sepah; Millena G. Bittencourt; Mohammad A. Sadiq; Owhofasa O. Agbedia; Hongting Liu; Mehreen Ansari; Zubir S. Rentiya; Daniel A. Ferraz; Quan Dong Nguyen Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 130 sur 222 View Presentation 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 3433 - C0154. Assessing retinal detailed structure in pathological myopia with adaptive optics scanning laser ophthalmoscope na liao; Chaohong Li; Yiyu Li; Hao Chen; Qinmei Wang View Presentation 3434 - C0155. Variation of cone density assessed by Adaptive Optics Retinal Camera with axial length meillat mathieu; Perle TUMAHAI; Mélanie Bidaut-Garnier; Guillaume Debellemaniere; Mathieu Flores; Michel Montard; Bernard Y. Delbosc; Maher Saleh View Presentation 3435 - C0156. Quantification and Comparison of Cone density, Outer Nuclear Layer and Henle’s Fiber Layer Thickness Using High-Resolution Imaging Grace K. Han; Jan Kristine T. Bayabo; Brandon J. Lujan; Jessica I. Morgan View Presentation 3436 - C0157. Correlation of outer nuclear layer thickness with cone density values in patients with retinitis pigmentosa and healthy subjects Moreno Menghini; Brandon J. Lujan; Shiri Zayit-Soudry; Reema Syed; Travis Porco; Jan Kristine T. Bayabo; Joseph Carroll; Austin Roorda; Jacque L. Duncan View Presentation 3437 - C0158. Repeatability of Cone Density Measurements in Healthy Subjects Using Commercially Available Flood-Illuminated Adaptive Optics Shu Feng; Anupam K. Garg; Ambar Faridi; Jonathan D. Fay; Hope E. Titus; Travis B. Smith; Keith V. Michaels; Mark E. Pennesi View Presentation 3438 - C0159. High resolution imaging of photoreceptors in healthy humans of different ages eyes using RTX-1 ™ Adaptive Optics Retinal camera Perle TUMAHAI; meillat mathieu; Melanie Bidaut-garnier; Guillaume Debellemaniere; Mathieu Flores; Michel Montard; Bernard Y. Delbosc; Maher Saleh View Presentation 3439 - C0160. Quantitative analysis of cone photoreceptor distribution in aged patients using an adaptive optics fundus camera Ryo Obata; Xue Tan; Kayo Kure; Frida Rosander; Yasuo Yanagi View Presentation 3440 - C0161. Reproducibility of photoreceptor imaging by Adaptive Optics Retinal Camera Mélanie Bidaut-Garnier; Mathieu Flores; Perle TUMAHAI; meillat mathieu; Guillaume Debellemaniere; Marc Puyraveau; Bernard Y. Delbosc; Michel Montard; Maher Saleh View Presentation 3441 - C0162. Analysis of the Photoreceptor Mosaic in Patients with Each Stage of Dry Age-Related Macular Degeneration (AMD): Cone Density and Spacing as Image-Based Biomarkers Adam Boretsky; Faraz Khan; Frederik J. van Kuijk; Massoud Motamedi View Presentation 3442 - C0163. High Resolution Imaging with Adaptive Optics in Patients with VogtKoyanagi Harada Disease Kiyoko Gocho; Sachiko Kikuchi; Takenori Kabuto; Hisatomo Takahashi; Shuhei Kameya; Kunihiko Yamaki; Hiroshi Takahashi View Presentation 3443 - C0164. Spectral-Domain Optical Coherence Tomographic Findings in Acute Zonal Occult Outer Retinopathy (AZOOR)-complex at Initial Visit to the Hospital Yoshitsugu Matsui; Mai Miyata; Hisashi Matsubara; Shinji Ueno; Shu Kachi; Yasuki Ito; Hiroko Terasaki; Mineo Kondo View Presentation 3444 - C0165. Evidence of Retinal Damage in Chloroquine/Hydroxychloroquine Maculopathy as Revealed by High Resolution Imaging: A Case Report Utilizing Adaptive Optics Scanning Laser Ophthalmoscopy SongEun Lee; Sung Pyo Park; Eun Jin Bae; Stephen H. Tsang; Stanley Chang View Presentation 3445 - C0166. Adaptive Optics Scanning Laser Ophthalmoscopy and High Resolution Imaging in Autosomal Dominant Retinitis Pigmentosa Caused by a Novel PRPF31 Nonsense Mutation Jessica I. Morgan; Meera Sivalingam; Grace K. Han; Albert M. Maguire; Brian J. Forbes; Xiaowu Gai; Eric A. Pierce; Jean Bennett; Daniel C. Chung View Presentation 3446 - C0167. Cone Abnormalities in Fundus Albipunctatus Associated with RDH5 Mutation Using Adaptive Optics Scanning Laser Ophthalmoscopy Sotaro Ooto; Yukiko Makiyama; Masanori Hangai; Ken Ogino; Norimoto Gotoh; Akio Oishi; Nagahisa Yoshimura View Presentation 3447 - C0168. Adaptive Optics Scanning Laser Ophthalmoscopy and Multi-Modality Clinical Imaging in a Patient with Gyrate Atrophy Eva S. Klinman; Albert M. Maguire; Grace K. Han; Jessica I. Morgan View Presentation 3448 - C0169. Cellular Imaging Demonstrates Genetic Mosaicism in Heterozygous Carriers of an X-Linked Ciliopathy Gene Sung Pyo Park; In Hwan Hong; Winston Lee; Marcela Marsiglia; Takeshi Kitamura; Stephen H. Tsang; Stanley Chang View Presentation 3449 - C0170. Disruption of the Human Cone Photoreceptor Mosaic from a Defect in NR2E3 Transcription Factor Function Frank S. Siringo; Sung Pyo Park; In Hwan Hong; Stephen H. Tsang; Winston Lee; Jason Horowitz; Rando Allikmets; Stanley Chang; Suzanne Yzer View Presentation 3450 - C0171. Cellular Imaging after Remission from Diabetic Macular Edema Ching-Lung Chen; Sung Pyo Park; Takeshi Kitamura; Stanley Chang View Presentation 3451 - C0172. Photoreceptor Structure in Presumed Non-Neoplastic Autoimmune Retinopathy David B. Kay; Robert F. Cooper; Drew H. Scoles; Fouad R. Zakka; Vesper Williams; Alfredo Dubra; Joseph Carroll; Kimberly E. Stepien View Presentation 3452 - C0173. Cone photoreceptors at the fovea after serous retinal detachment observed with adaptive optics fundus camera (rtx1) Atsushi Hayashi; Tomoko Nakamura; Naoki Tojo; Tomoko Ueda; Toshihiko Oiwake; Akio Miyakoshi; Hironori Ozaki View Presentation 3453 - C0174. Evaluation of cone density after retinal detachment surgery using an Adaptive Optics camera Maher Saleh; meillat mathieu; Mélanie Bidaut-Garnier; Perle TUMAHAI; Guillaume Debellemaniere; Mathieu Flores; Michel Montard; Bernard Y. Delbosc View Presentation 3454 - C0175. Recovery of photoreceptors in the macula of idiopathic choroidal neovascularization observed with adaptive optics fundus camera Tomoko Nakamura; Toshihiko Oiwake; Tomoko Ueda; Akio Miyakoshi; Atsushi Hayashi View Presentation 3455 - C0176. High resolution cone photoreceptor imaging analysis of an occult macular dystrophy patient with RP1L1 mutation Shuhei Kameya; Takenori Kabuto; Sachiko Kikuchi; Hisatomo Takahashi; Kiyoko Gocho; Kunihiko Yamaki; Hiroshi Takahashi View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 131 sur 222 345. Corneal Surgery Non-refractive II and Keratoprosthesis Moderator(s): Mary Daly (VA Boston Healthcare System) and Mark Wilkins (Moorfields Eye Hospital) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM View Session Details 3456 - D0083. A Prospective Trial Evaluating Scleral Rebound Tonometry Shuchi B. Patel; Sara L. Duke; Andrew Logeman View Presentation 3457 - D0084. Limbal and Scleral Pneumatonometer versus Manometric Reading in Cadaver Eyes with Type 1 Boston Keratoprosthesis Janet M. Lim; Genie Bang; Thasarat S. Vajaranant; Ahmad A. Aref; Maria S. Cortina; Jose De la Cruz View Presentation 3458 - D0085. Analysis of Eyes Undergone Boston Keratoprosthesis transplantation Using Anterior Segment Optical Coherence Tomography Yumiko HIrayama; Naoki Toriyama; Daisuke Tomida; Kenji Konomi; Yoshiyuki Satake; Jun Shimazaki View Presentation 3459 - D0086. Boston type 1 keratoprosthesis: surgical indications, short term retention and achievement of 20/200 vision Kristine Lo; Kathryn Colby; James Chodosh View Presentation 3460 - D0087. The Boston Keratoprosthesis Type I in Mucous Membrane Pemphigoid Sotiria Palioura; Bryan Kim; Claes H. Dohlman; James Chodosh View Presentation 3461 - D0088. Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) for Visual Rehabilitation in Patients with Corneal Ectasia Nadeem H. Fatteh; Karen Deloss; Christopher T. Hood View Presentation 3462 - D0089. Risk Factors Associated with Cystoid Macular Edema After Boston Keratoprosthesis Type 1 Implantation Kaitlyn M. Wallace; Joshua H. Hou; Randee C. Miller; Clement C. Chow; Jose De la Cruz; Felix Y. Chau; Maria S. Cortina View Presentation 3463 - D0090. In vivo evaluation of microbial infection on surface functionalized titanium as artificial cornea candidate material Xiao-Wei Tan; Rajamani Lakshminarayanan; Gwendoline Goh; Melina Setiawan; Shouping Liu; Roger W. Beuerman; Donald T. Tan; Jodhbir S. Mehta View Presentation 3464 - D0091. Bandage CL fitting characteristics and complications in patients with Boston Type I keratoprosthesis surgery Ellen Shorter; Charlotte E. Joslin; Timothy T. McMahon; Jose De la Cruz; Maria S. Cortina View Presentation 3465 - D0092. Keratoprosthesis Imaging Using Anterior Segment Optical Coherence Tomography to Detect Graft Host Defects in the Clinic and in the Operating Room Mark N. Welch; Michael Banitt; Audina M. Berrocal; Victor L. Perez View Presentation 3466 - D0093. Anterior Segment Optical Coherence Tomography in Patients with Boston Type I Keratoprosthesis Allows Early Detection and Monitoring of Corneal and Scleral Melts David Sola-Del Valle; Bernardo M. Cavalcanti; Andrea Cruzat; Claes H. Dohlman; Pedram Hamrah View Presentation 3467 - D0094. Scanning Laser Ophthalmoscope Microperimetry through the Boston Keratoprosthesis Rony R. Sayegh; Claes H. Dohlman; Mary Lou Jackson View Presentation 3468 - D0095. Assessment of Titanium Modification for Coloring the Backplate of Boston Keratoprosthesis Eleftherios I. Paschalis; James Chodosh; Sandra J. Spurr-Michaud; Andrea Cruzat; Allyson Tauber; Irmgard Behlau; Ilene K. Gipson; Claes H. Dohlman View Presentation 3469 - D0096. Femto-second-laser and eximer-laser assisted preparation of biosynthetic corneal collagen donor implants and the recipient bed Raphael T. Neuhann; Kerstin M. Wand; Karin Kobuch; Michael Baumann; May Griffith; Mohammad M. Islam; Johannes Junger; Roland Ritter; Chris Lohmann View Presentation 3470 - D0097. Imaging of Surface Defects and Biofilm Formation of Extruded Keratoprostheses Using Confocal Microscopy Heather A. Durkee; Darlene Miller; Victor L. Perez; Yoh Sawatari; Aleksandra V. Rachitskaya; Audina M. Berrocal; Eduardo C. Alfonso; Jean-Marie A. Parel View Presentation 3471 - D0098. Improvement of the water tightness of a monobloc keratoprosthesis with the use of a surgical bio-glue. Preliminary results in dogs Pierre F. Isard; Marielle Mentek; Thomas Dulaurent View Presentation 3472 - D0099. Agreement among Transpalpebral, Transcleral and Tactile Intraocular Pressure Measurements in Eyes with Type 1 Boston Keratoprosthesis Jessica L. Liu; Thasarat S. Vajaranant; Maria S. Cortina; Jacob T. Wilensky View Presentation 3473 - D0100. Retinal Detachments in Eyes After Boston Keratoprosthesis Type 1 Sachin Jain; Clement C. Chow; Jennifer I. Lim; Lawrence J. Ulanski; Jose De la Cruz; Maria S. Cortina; Felix Y. Chau View Presentation 3474 - D0101. Implantation of Biosynthetic Collagen III Corneal Implants in vivo in Rabbit Eyes: Surgical Technique and Clinical Performance Karin Kobuch; Raphael T. Neuhann; Kerstin Wand; Johannes Junger; Michael Baumann; Roland Ritter; Mohammad M. Islam; May Griffith; Chris Lohmann View Presentation 3475 - D0102. The effect of the presence of preoperative silicone oil, absence of prior corneal surgery, and postoperative scleral contact lens use on Boston keratoprosthesis outcomes Kareem Moussa; John Petrowski; Natalie A. Afshari View Presentation 3476 - D0103. Evaluation Of The Interface Between Keratoprosthesis and Donor Cornea By Anterior Segment OCT Riccardo Scotto; Marina Papadia; Alessandro Bagnis; Carlo Enrico Traverso View Presentation 3477 - D0104. Chondro-ocular graft transfer:: An alternative to allograft transplantation? David Myung; Christopher N. Ta; Edward Yung; Curtis W. Frank View Presentation 3478 - D0105. Polydopamine-coated and polyethylene glycol-impregnated corneas as tissue carriers for the Boston Keratoprosthesis Sara Bozorg; Kyung Jae Jeong; Samer N. Arafat; Daniel S. Kohane; Claes H. Dohlman View Presentation 3479 - D0106. Designing a Novel Porous Keratoprosthesis to Promote Cornea Cell Ingrowth Amelia L. Zellander; Richard A. Gemeinhart; Behrad Milani; Ali R. Djalilian; Mohsen Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 132 sur 222 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM Makhsous; Michael Cho View Presentation 3480 - D0107. A fish scale-derived scaffold for corneal reconstruction T H. van Essen; Sarah J. Sparks; Lisanne van Zijl; Greg Chen; Chien C. Lin; Horng J. Lai; Gregorius P. Luyten; Abdoelwaheb El Ghalbzouri; Martine J. Jager View Presentation 3481 - D0108. IMPROVEMENTS IN THE MODIFIED OSTEO-ODONTO KERATOPROSTHESIS (MOOKP) SURGERY TECHNIQUE Mariela C. Aguilar; Yoh Sawatari; Alex Gonzalez; William Lee; Cornelis J. Rowaan; Deepa Sathiah; Darlene Miller; Victor L. Perez; Eduardo C. Alfonso; Jean-Marie A. Parel View Presentation 346. Glaucoma Moderator(s): Kuldev Singh (Stanford University) and George Spaeth (Wills Eye Institute) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM View Session Details 3482 - D0158. Glaucoma and artificial tears Rodrigo M. Torres; Pablo G. Lodolo View Presentation 3483 - D0159. Which Scheimpflug parameters are most predictive in detecting narrow anterior chamber angles? Afsun Sahin; Zuhat Usalp; Nilgun Yildirim; Özge Bolluk; Ahmet Özer View Presentation 3484 - D0160. Factors associated with the onset of treatment in fellow eyes in the Collaborative Initial Glaucoma Treatment Study David C. Musch; Leslie M. Niziol; Brenda W. Gillespie View Presentation 3485 - D0161. Measures of Intraocular Pressure Variation and Risk of Developing Openangle Glaucoma: The Los Angeles Latino Eye Study Xuejuan Jiang; Rohit Varma; Mina Torres; Stanley P. Azen; Brian A. Francis; Vikas Chopra; Betsy Bao-Thu Nguyen View Presentation 3486 - D0162. THE AFRICAN DESCENT AND GLAUCOMA EVALUATION STUDY (ADAGES): PREDICTORS OF GLAUCOMA PROGRESSION IN GLAUCOMA SUSPECTS Naira Khachatryan; Atsuya Miki; Sonia Jain; Feng He; Naama Hammel; Felipe A. Medeiros; Robert N. Weinreb; Jeffrey M. Liebmann; Christopher A. Girkin; Linda M. Zangwill View Presentation 3487 - D0163. Baseline Prognostic Factors Predict Rapid Progression Jun Mo Lee; Joseph Caprioli; Kouros Nouri-Mahdavi; Abdelmonem Afifi; Esteban Morales; Meera Ramanathan; Fei Yu; Anne L. Coleman View Presentation 3488 - D0164. A Korea National Health and Nutrition Examination Survey (KNHANES) (2009-2010)-based analysis of intraocular pressure and associated systemic factors in a Korean population Mi Jeung Kim; Ki Ho Park; Jin Wook Jeoung; Seok Hwan Kim; Yun Jeong Choi; Kyoung Nam Kim View Presentation 3489 - D0165. The association of Diurnal Intraocular Pressure (DIOP) fluctuation and anterior chamber angle dimensions in patients with primary angle closure, and the association with peripheral anterior synechiae (PAS): The Investigating Management of Angle Closure and Treatment (IMPACT) study Laura Sanchez Parra; Roger Buckley; Shahina Pardhan; Rupert R. Bourne View Presentation 3490 - D0166. Female Reproductive Factors and Major Eye Diseases in Asian Women The Singapore Malay Eye Study Janice Lam; Wan Ting Tay; Tin Aung; Seang-Mei Saw; Tien Y. Wong View Presentation 3491 - D0167. Cost of glaucoma in the XXI century. Economic Analysis Gabriel Lazcano-Gomez; Jesus Jimenez-Roman View Presentation 3492 - D0168. Association between Thyroid Conditions and Open-Angle Glaucoma in the United States Medicare Population Judy L. Chen; Fei Yu; Flora Lum; Anne L. Coleman View Presentation 3493 - D0169. Normal tension glaucoma prevalence in sleep apnea patients with type 2 diabetes, interest of a new medical device Ru-Sleeping© in ophthalmology Corinne Dot; Emilie Agard; Hussam El Chehab; Ikrame Douma; Guillaume RactMadoux; Olivier C. Coste View Presentation 3494 - D0170. Patients with advanced glaucoma need different treatment approach Petja I. Vassileva; Yordanka Kirilova; Kameliya Naldzhieva View Presentation 3495 - D0171. Incidence of trabeculectomy related complications at various Mitomycin C Concentrations from 1985 to 2010 in Olmsted County, MN Jessica A. Adefusika; Cheryl L. Khanna View Presentation 3496 - D0172. Clinical and Demographic features in patients with Primary Open angle glaucoma in the Asociación Para Evitar la Ceguera en México maria garcia ibarra; Jesus Jimenez-Roman; Felix Gil Carrasco View Presentation 3497 - D0173. Correlation between decision to refer for glaucoma and diagnosis of glaucoma Preeti J. Thyparampil; Benjamin J. Frankfort; Silvia D. Orengo-Nania View Presentation 3498 - D0174. Impact of Patient Comprehension on Treatment Success in Glaucoma Anjali Sheth; Wendy A. Kirkland; Sanna D. Ronkainen; Carter N. Kirk; Sasikala Pillai View Presentation 3499 - D0175. Association between Myopia and Glaucoma in a Young Adult Population Mary Qiu; Sophia Wang; Kuldev Singh; Shan C. Lin View Presentation 3500 - D0176. Medication possession ratio and its related factors among Japanese glaucoma patients Kazuyoshi Kitamura; Hiroshi Yokomichi; Zentaro Yamagata; Kenji Kashiwagi View Presentation 3501 - D0177. Analysis of hematological and biochemical data in normal tension glaucoma patients Morio Ueno; Yoko Ikeda; Kengo Yoshii; Haruna Yoshikawa; Yuko Maruyama; Kazuhiko Mori; Kei Tashiro; Shigeru Kinoshita View Presentation 3502 - D0178. Prevalence of Open-angle glaucoma in Vitrectomized Eyes. The PR.O.V.E study ANDREA GOVETTO; Ramón Domínguez Fernández; Maria Luisa Landaluce; Maria Teresa Alves Perez; Ramon Lorente View Presentation 3503 - D0179. CORRELATION BETWEEN CORNEAL AND OPTIC NERVE HEAD PARAMETERS Federico Saenz-Frances; Lara Borrego; Clara Berrozpe Villabona; LAURA MORALES- Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 133 sur 222 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM FERNANDEZ; Jose M. Martinez de la Casa; Julian Garcia-Feijoo View Presentation 3504 - D0180. Anterior Chamber Depth and Lens Thickness in African-Americans with Age-Related Long Anterior Zonules Daniel K. Roberts; Bruce A. Teitelbaum; David D. Castells; Janis E. Winters; Jacob T. Wilensky View Presentation 3505 - D0181. Intraocular pressure and central corneal thickness in an old French population: The MONRACHET study Alain M. Bron; Anna Francoz; Caroline Fiet; Christine Binquet; Claire Bonython-Kopp; Christophe Tzourio; Niyazi Acar; Lionel Bretillon; Catherine Creuzot-Garcher View Presentation 3506 - D0182. The Ocular Hypertension Treatment Study (OHTS): Does Higher LongTerm IOP Variability Increase Risk Of Developing Primary Open Angle Glaucoma (POAG) in the Medication Group? Mae O. Gordon; Julia A. Beiser; J. Phillip Miller; Michael A. Kass; Feng Gao View Presentation 3507 - D0183. What do patients know about glaucoma? Effects of education at 1 and 6 months after the program Fabian S Lerner; Jaime I. Yankelevich View Presentation 3508 - D0184. Variability of trabeculectomy among glaucoma surgeons: a survey from different countries Glauco B. Almeida; Camila Zangalli; Luciana M. Alencar; Marcelo Hatanaka; Eduardo L. Ferreira; George L. Spaeth View Presentation 3509 - D0185. The Estimated Impact of Changing Refractive Errors on the Future Rates of Angle-closure and Open Angle Glaucoma in Asia Naomi V. Odell; Mark A. Slabaugh; Leona Ding View Presentation 3510 - D0186. The Relationship of Body Mass Index (BMI) to Glaucoma Jessica Prince; Noah Geberer; Wen-Jeng (Melissa) Yao; Barrett Katz View Presentation 3511 - D0187. EYES WITH LARGE OPTIC DISC CUPPING AND NORMAL INTRAOCULAR PRESSURE: CLINICAL AND EPIDEMIOLOGICAL DIFFERENCES BETWEEN THOSE WITH AND WITHOUT GLAUCOMA Tiago S. Prata; Marina C. Sousa; Mauro T. Leite; Augusto Paranhos View Presentation 3512 - D0188. Longitudinal analysis of age related changes in intraocular pressure in South Koreans SungUk Baek; Changwon Kee; Wool Suh View Presentation 3513 - D0189. Evaluation of Ocular Surface Disease in Patients with Glaucoma Priya M. Mathews; Pradeep Y. Ramulu; David S. Friedman; Esen K. Akpek View Presentation 3514 - D0190. Reduced social participation among seniors with non refractive vision problems and glaucoma Yaping Jin; Elizabeth Badley; Monique Gignac; Yvonne M. Buys; Kednapa Thavorn; Graham E. Trope View Presentation 3515 - D0191. Using a Structural Equation Measurement Model (SEMM) for Nested Data to Describe Agreement among Lamina Cribrosa Pore Segmentation Methods Richard A. Bilonick; Bo Wang; Zach Nadler; Gadi Wollstein; Hiroshi Ishikawa; Yun Ling; Larry Kagemann; Joel S. Schuman View Presentation 3516 - D0192. BRIDGING THE MAJOR CLINICAL TRIALS AND EVERYDAY CLINICAL PRACTICE: CENTRAL CORNEAL THICKNESS AND VISUAL FIELD DAMAGE ARE INDEPENDENT RISK FACTORS FOR PROGRESSION IN A 6-YEAR RETROSPECTIVE EVALUATION OF PATIENTS' ELECTRONIC CHART RECORDS Stefano A. Gandolfi; Daniela Paoli View Presentation 3517 - D0193. Impact of Educational Intervention on Compliance with Topical Therapy for Glaucoma Shani Reich; Justin E. Rome; Jack Manns; Lilly Droll; Joseph Zelefsky View Presentation 3518 - D0194. First-degree Consanguinity as a risk factor to developing primary openangle Glaucoma in Mexican families Elia Chavez; Jose A. Paczka; Abraham Soto-Gomez; Miriam A. Ramos-Hernandez View Presentation 3519 - D0195. Associations between Systemic Factors and Longitudinal Analyses of Intraocular Pressure: Mean, Peak and Variability Thasarat S. Vajaranant; Charlotte E. Joslin View Presentation 3520 - D0196. Comparison of the sensitivity and specificity of the Von Herick test and ocular biometric parameters as screening tests in prevalent and incident angle closure disease in a population based study Ronnie J. George; Rashima Dinesh; Manish Panday; Ramesh S Ve; Vijaya Lingam View Presentation 3521 - D0197. Glaucoma Awareness in Relatives of Patients Diagnosed with Glaucoma aaron smith; Jennifer Oakley; Suzanne T. Hoadley; Erin J. Smith; Omolola O. Idowu View Presentation 3522 - D0198. The Glaucoma Treatment Compliance Assessment Tool (GTCAT) has an organizational structure consistent with the Health Belief Model Gordon Barker; Paul F. Cook; Malik Y. Kahook; Jeffrey Kammer; Steven L. Mansberger View Presentation 3523 - D0199. Glaucoma in Patients After Iodine-125 Brachytherapy for Uveal Melanoma Crystal Hung; Tara McCannel; Simon K. Law; JoAnn A. Giaconi View Presentation 3524 - D0200. Relationship between eye shape and the risk for glaucoma Divakar Gupta; Daniel B. Moore; Karine D. Bojikian; Mark A. Slabaugh View Presentation 3525 - D0201. Latent Growth Curve Model for Calibration between Measurements Obtained by Multiple Devices Yun Ling; Richard A. Bilonick; Igor I. Bussel; Hiroshi Ishikawa; Gadi Wollstein; Larry Kagemann; Ian A. Sigal; Joel S. Schuman View Presentation 347. Trabecular Meshwork II Moderator(s): Michael Fautsch (Mayo Clinic) and Robert Wordinger (UNT Health Science Center) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM View Session Details 3526 - D0255. Aging of Schlemm’s canal in primary open angle glaucoma in hereditary and non-hereditary cases Teruhiko Hamanaka; Tetsuro Sakurai; Akira Matsuda; Akira Murakami View Presentation 3527 - D0256. A magnetic bead-based method for mouse trabecular meshwork cell isolation Weiming Mao; Yang Liu; Robert J. Wordinger; Abbot F. Clark Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 134 sur 222 View Presentation 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 3528 - D0257. Live Imaging of Actin Structure in Human Trabecular Meshwork Jeremy Hwang; Jose M. Gonzalez; James C. Tan View Presentation 3529 - D0258. Dynamic Re-establishment of the Actin Cytoskeleton Impacts the Mechanotranducing Pathway in Human Trabecular Meshwork Cells Paul Russell; Sara M. Thomasy; Christopher J. Murphy View Presentation 3530 - D0259. Imaging the Effects of Prostaglandins on Cultured Trabecular Meshwork Cells by Coherent Anti-Stokes Raman Scattering (CARS) David A. Ammar; Omid Masihzadeh; Malik Y. Kahook; Tim C. Lei View Presentation 3531 - D0260. Transforming Growth Factor-β2 (TGF-β2) Induces Expression of Biologically Active Bone Morphogenetic Protein-1 (BMP1) in Human Trabecular Meshwork Cells Tara Tovar-Vidales; Ashley M. Fitzgerald; Abbot F. Clark; Robert J. Wordinger View Presentation 3532 - D0261. Dexamethasone induces stress fiber re-arrangement through noncanonical Wnt signaling in trabecular meshwork cells Yong Yuan; Chia-Yang Liu; Winston W. Kao View Presentation 3533 - D0262. Proteomic Analysis of Trabecular Meshwork Extracellular Matrix Vasanth Rao; Rupalatha Maddala; Nikolai P. Skiba View Presentation 3534 - D0263. Microspheres (MS) Perfused into the Anterior Chamber (AC) enter the Lumen of Cylindrical Structures Spanning Schlemm’s canal (SC) Elizabeth Martin; Nicolette Orkney; Murray A. Johnstone View Presentation 3535 - D0264. Benzalkonium Chloride is Cytotoxic While Preservative-free Tafluprost is Cytoprotective in Human Trabecular Meshwork Cells Caitlin A. Chang; Cindy M. Hutnik View Presentation 3536 - D0265. Expression of Stem Cell Markers in the Bovine Corneal Endothelium, Insert Region and Trabecular Meshwork Wing Yan Yu; Carl M. Sheridan; Ian Grierson; Amy C. Lo; Sai Hung David Wong View Presentation 3537 - D0266. Metabolic Dependence of Conventional Outflow Facility in Mice Alexandra Boussommier Calleja; W Daniel Stamer; C R. Ethier; Darryl R. Overby View Presentation 3538 - D0267. Schlemm's Canal (SC) Inner Wall Pores Correlate with Segmental Outflow in Human Eyes C R. Ethier; Sietse T. Braakman; Arthur T. Read; Darren W. Chan; Darryl R. Overby View Presentation 3539 - D0268. Transcriptional Profiling of Human Schlemm’s Canal Cells Following Latanoprost, Bimatoprost and Prostaglandin F2alpha (PGF2α) Treatment Nelson S. Winkler; Uttio Roy Chowdhury; Michael P. Fautsch View Presentation 3540 - D0269. Microparticle Delivery of Matrix Metalloproteinase-3 to Trabecular Meshwork Cells Beatrice Yue; Sanja B. Turturro; Suhair Sunoqrot; Hongyu Ying; Seungpyo Hong View Presentation 3541 - D0270. CLINICAL EFFICACY OF ULTRASONIC CIRCULAR CYCLO COAGULATION IN REFRACTORY GLAUCOMA. PRELIMINARY RESULTS Paolo Fogagnolo; Maurizio Digiuni; Emanuele Maggiolo; Luca M. Rossetti View Presentation 3542 - D0271. EFFECT OF CELLULAR AND PLASMA FIBRONECTIN ISOFORMS ON NORMAL HUMAN TRABECULAR MESHWORK CELLS Wanda E. Medina-Ortiz; Robert J. Wordinger; Abbot F. Clark View Presentation 3543 - D0272. Decrease of nuclear Yes-associated protein (YAP) with human trabecular meshwork (HTM) cell passage Joshua Morgan; Christopher J. Murphy; Paul Russell View Presentation 3544 - D0273. Three-dimensional structure of the mouse ciliary muscle, its innervation and connections to the outflow tissues and choroid Elke Luetjen-Drecoll; Ozan Tektas; Darryl R. Overby View Presentation 3545 - D0274. Prdx6 abates the process of senescence and restores trabecular meshwork cell integrity by regulating Telomerase, p16 and p21 Expression Nigar Fatma; Eri Kubo; Bhavana Chhunchha; W Daniel Stamer; Dhirendra P. Singh View Presentation 3546 - D0275. ADAMTS4 activity and TIMP3 levels are modulated in trabecular meshwork cells with decreased hyaluronan synthesis Kate E. Keller; Yong-Feng Yang; Ying Ying Sun; Ted S. Acott View Presentation 3547 - D0276. MECHANICAL STRESS ACTIVATES AUTOPHAGY IN TRABECULAR MESHWORK CELLS Ping Xu; Kristine M. Porter; Nalla Thambi Jeyabalan; Paloma B. Liton View Presentation 3548 - D0277. DIMINISHED AUTOPHAGIC CAPACITY OF GLAUCOMATOUS TRABECULAR MESHWORK CELLS Kristine M. Porter; Ping Xu; W Daniel Stamer; Paloma B. Liton View Presentation 3549 - D0278. Overexpression of SPARC Upregulates Gremlin and Proteoglycans Opticin & Decorin Swarup S. Swaminathan; Dong-Jin Oh; Douglas J. Rhee View Presentation 3550 - D0279. Multimodal Microscopy of Aqueous Drainage Channels in Live Mice Jose M. Gonzalez; James C. Tan View Presentation 3551 - D0280. Transcriptional Co-regulatory Patterns Associated with TNFα Treatment of Trabecular Meshwork Cells Lauren Hayashi; Dongseok Choi; Kathryn Carr; Mary J. Kelley; Ted S. Acott View Presentation 3552 - D0281. Characterization of Sirtuin family protein expression in human trabecular meshwork cells Ayan Chatterjee; Sarah S. Oh; Guadalupe Villarreal; Douglas J. Rhee View Presentation 3553 - D0282. In situ 3D Distribution of Filamentous Actin in Mouse Trabecular Meshwork James C. Tan; Jose M. Gonzalez; MinHee K. Ko View Presentation 3554 - D0283. Effects of Calcitonin Gene Related Peptide on Bovine Trabecular Meshwork and Ciliary Muscle Dai Ogino; Shun Watanabe; Yusuke Ohta; Kota Fujiwara; Takeshi Yoshitomi View Presentation 3555 - D0284. Stem Cells from Trabecular Meshwork Home to Damaged TM Tissue in vivo Yiqin Du; Hongmin Yun; Enzhi Yang; Joel S. Schuman Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 135 sur 222 View Presentation 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 3556 - D0285. Identification of TGF-β2-induced Proinflammatory Cytokines Secreted from Cultured Trabecular Meshwork Cells Miyuki Inoue; Toshihiro Inoue; Tomokazu Fujimoto; Nanaka Awai-Kasaoka; Hidenobu Tanihara View Presentation 3557 - D0286. Type I collagen-induced Epithelial Mesenchymal Transition-like Phenomenon in Trabecular Meshwork Cells Ayako Fukushima; Eri Takahashi; Tomokazu Fujimoto; Sachi Kojima; Toshihiro Inoue; Hidenobu Tanihara View Presentation 3558 - D0287. Smad3 phosphorylation promotes Transforming Growth Factor-β2 mediated expression of endothelin-1 in human trabecular meshwork cells Cynthia L. Von Zee; Jonathan D. Lautz; Kelly Langert; Evan B. Stubbs View Presentation 3559 - D0288. Cuantitative study of the trabecular meshwork and its relationship to the morphometry of the eye in the normal population using an anterior segment Fourier Domain OCT José Fernández-Vigo López; José Ignacio Fernández-Vigo; CRISTINA FERNANDEZVIGO ESCRIBANO; Jose M. Martinez de la Casa; Julian Garcia-Feijoo View Presentation 3560 - D0289. Caveolins modulate ECM turnover by Trabecular Meshwork cells Mini Aga; Kate E. Keller; John M. Bradley; Ted S. Acott View Presentation 3561 - D0290. Artificial Simulation of Conventional Aqueous Humor Outflow Dynamics EUN KYOUNG KIM; Edward R. Chu; Aleksandr Yelenskiy; Jose M. Gonzalez; James C. Tan View Presentation 3562 - D0291. Trabecular Meshwork Cell Expression of Two Novel Mucin Genes Located in the MHC Class I Locus M Elizabeth Fini; Shinwu Jeong View Presentation 3563 - D0292. Effect of NaHS, a fast-releasing Hydrogen sulfide donor on Aqueous Humor Outflow in Porcine Trabecular Meshwork Ya Fatou Njie-Mbye; Jenaye Robinson; Anita Okpobiri; Madhura Chitnis; Catherine A. Opere; Sunny E. Ohia View Presentation 3564 - D0293. ZONULAR LIGAMENT DYSPLASIA IN BEAGLES WITH HEREDITARY PRIMARY OPEN ANGLE GLAUCOMA (POAG) Leandro B. Teixeira; Erin M. Scott; Simone Iwabe; Richard R. Dubielzig; Andras M. Komaromy View Presentation 3565 - D0294. Overexpression of GPR158, an Orphan Member of G Protein-Coupled Receptor Family C, Mimics Effects of Glucocorticoids on Trabecular Meshwork Cells Nitin L. Patel; Tatsuo Itakura; M Elizabeth Fini View Presentation 3566 - D0295. Extracellular Matrix Gene Expression Profiling of High and Low Flow Areas of Human Trabecular Meshwork Janice A. Vranka; Kate E. Keller; Ted S. Acott View Presentation 3567 - D0296. Oxidative Stress Impacts On Barrier Function of Porcine Angular Aqueous Plexus Cell Monolayers Yuan Lei; W Daniel Stamer; Jihong Wu; Xinghuai Sun View Presentation 348. Anterior Segment Imaging Moderator(s): Joseph Izatt (Duke University ) and Jianhua Wang (Bascom Palmer Eye Inst Lib) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM View Session Details 3568 - D0297. Tear meniscus volume changes in external dacryocystorhinostomy (exDCR) evaluated with quantitative measurement using anterior segment optical coherence tomography (AS-OCT) Kazuyoshi Ohtomo; Takashi Miyai; Reina Fukuda; Tomohiko Usui; Rika Shirakawa; Takashi Ueta; Shiro Amano; Miyuki Nagahara View Presentation 3569 - D0298. Inter- and Intra-Observer Agreement and Repeatability of Imaging the Meibomian Glands with the OCULUS Keratograph 4 and Keratograph 5M William Ngo; Sruthi Srinivasan; Marc-Matthias Schulze; Lyndon W. Jones View Presentation 3570 - D0299. Ocular coherence tomography (OCT) guided adjustment of Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) device fit can treat device induced corneal edema Kristin O. Chapman; Ana G. Alzaga Fernandez; Michelle N. Lee; Kimberly C. Sippel; Priyanka Sood; Ryan M. St Clair; Christopher E. Starr; Jessica Ciralsky; Mark Rosenblatt View Presentation 3571 - D0300. Ultrasonic Biomicroscopy as a complementary tool for the evaluation of diseases of the lacrimal drainage system Sara I. Plazola; Melissa Flores; Alejandra Guzman View Presentation 3572 - D0301. An Anterior Chamber Optical Tissue Phantom for AC-OCT Temple S. Rowe View Presentation 3573 - D0302. 360 Degree In-Vivo Imaging of the Human Limbus by Optical Coherence Tomography Kira L. Lathrop; Hiroshi Ishikawa; Larry Kagemann; Joel S. Schuman View Presentation 3574 - D0303. In vivo live-cell imaging of human trabecular meshwork cells under laminar flow Akhilesh Kumar; Xingjuan Chen; Michael Conwell; Na Luo; Alexander G. Obukhov; Yang Sun View Presentation 3575 - D0304. Architecture for Angle Closure Glaucoma: Novel methods for Imaging, Risk Assessment and Screening (AGAR) Jimmy Jiang Liu; Yanwu Xu; Beng Hai Lee; Min Thet Htoo; Damon Wong; Baskaran Mani; Tin Aung; Tien Y. Wong View Presentation 3576 - D0305. Comparative Study of the Nidek Specular Microscope CEM-530 and the CELLCHEK XL Predicate Device for the Measurements of Endothelial Cell Density Measurements, Coefficient of Variation of Endothelial Cell Area, and percent Hexagonality Ron Kaiser; Ryan Bouchard; Aron Shapiro; Gail L. Torkildsen; Joseph B. Ciolino; Toshio Murata View Presentation 3577 - D0306. Confocal Microscopy of Corneal Nerves for Early Detection of Diabetic Neuropathy in Recently Diagnosed Type 2 Diabetic Patients Andrey Zhivov; Dan Ziegler; Sabine Peschel; Stephan Allgeier; Karsten Winter; Bernd Koehler; Nikolaos Papanas; Oliver Stachs; Michael Roden; Rudolf F. Guthoff View Presentation 3578 - D0307. Diabetic Foot Syndrome and Changes of Corneal Subbasal Nerve Plexus Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 136 sur 222 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM in Diabetes Type 2 Congolese Patients Sabine Peschel; Andrey Zhivov; Hans-Christof Schober; Oliver Stachs; Marie Therese N. Bambi; Ngoy J. Kilangalanga; Karsten Winter; Rudolf F. Guthoff View Presentation 3579 - D0308. Anterior Segment Fluorescein Angiography Findings in Patients with Fuchs’ Heterochromic Iridocyclitis compared with Normal Subjects cyntia solis; Stephanie Voorduin; Francisco Martinez; Teresa Valdez View Presentation 3580 - D0309. Real-time anterior segment biometry and its relation to accommodative response Dexi Zhu; Meixiao Shen; Lin Leng; Yilei Shao; Jianhua Wang; Fan Lu View Presentation 3581 - D0310. Repeatability of Crystalline Lens Thickness Measurements in the Accommodating Eye Lesley A. Doyle; Julie-Anne Little; Kathryn J. Saunders View Presentation 3582 - D0311. Automatic biometry of human anterior segment during accommodation Meixiao Shen; Dexi Zhu; Yilei Shao; Lin Leng; Jianhua Wang; Fan Lu View Presentation 3583 - D0312. Corneal Alkali Burn Induces Inflammatory Changes In The Central Nervous System Fabio Bignami; Giulio Ferrari; Chiara Giacomini; Eleonora Capitolo; Linda Chaabane; Paolo Rama View Presentation 3584 - D0313. A Novel Telemedicine Device for Diagnosis of Corneal Abrasions and Ulcers in Resource-Poor Settings Robi N. Maamari; Somsanguan Ausayakhun; Todd P. Margolis; Thomas M. Lietman; Daniel A. Fletcher; Jeremy D. Keenan View Presentation 3585 - D0314. Hyperglycemia-induced corneal abnormalities in diabetic rats and humans Laura Kowalczuk; Gaël Latour; Jean-Louis Bourges; Michèle Savoldelli; Jean-Claude P. Jeanny; Marie-Claire Schanne-Klein; Francine F. Behar-Cohen View Presentation 3586 - D0315. Real-time intraoperative assessment of the cornea with microscope integrated optical coherence tomography Justin V. Migacz; Anthony N. Kuo; Adam M. Dubis; Oscar Carrasco-Zevallos; Cynthia A. Toth; Joseph A. Izatt View Presentation 3587 - D0316. Intraoperative Optical Coherence Tomography in Deep Anterior Lamellar Keratectomy John Au; William J. Dupps; Jeff Goshe; Justis P. Ehlers; Gina M. Smith View Presentation 3588 - D0317. Fluorescence multi-laser scanning microscopy of the cornea and ocular adnexa: a new era for functional confocal microscopy in ophthalmology Gilles Thuret; Marine Espinasse; Damien Grivet; Zhiguo He; Nelly Campolmi; Jean Luc Perrot; Elisa Cinotti; Fabien Forest; Michel Peoc'h; Philippe Gain View Presentation 3589 - D0318. Analysis of Anterior Chamber Inflammation by Spectral Domain Optical Coherence Tomography Sumit Sharma; Kimberly Baynes; Peter K. Kaiser; Careen Y. Lowder; Sunil K. Srivastava View Presentation 3590 - D0319. Ultrabiomicroscopy in patients with uveitis and it's correlation with clinical findings Stephanie Voorduin; Azucena A. Mendoza ; Daniel Salas; Milton M. Maldonado; Francisco Martinez; Teresa Valdez View Presentation 349. Vitreoretinal Imaging Moderator(s): Srinivas Sadda (Doheny Eye Institute - USC) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM View Session Details 3591 - D0320. Utility of Infrared Imaging For Visualizing Persistent Subretinal Fluid After Retinal Detachment Surgery Do Gyun Kim; Dennis P. Han; David V. Weinberg; Judy E. Kim View Presentation 3592 - D0321. Fundus Autofluorescence Findings and Ancillary Imaging in MEWDS Patients without White Dots Anthony Joseph; Ehsan Rahimy; K Bailey Freund; David Sarraf View Presentation 3593 - D0322. Imaging of Human Retina using Spectral Optical Coherence Tomography and high sensitive autofluorescence detection Katarzyna Komar; Patrycjusz Stremplewski; Maciej Szkulmowski; Marta Motoczynska; Maciej Wojtkowski View Presentation 3594 - D0323. Optos fundus imaging in patients with keratoprosthesis William D. Terrell; Ahmad Tarabishy; Andrew Hendershot; Rebecca Kuennen; Thomas Mauger; Colleen M. Cebulla View Presentation 3595 - D0324. MULTIMODALITY IMAGING OF RETINAL ASTROCYTIC HAMARTOMA Lucía De Pablo; Ekaterina Semenova; Paul T. Finger View Presentation 3596 - D0325. Optical coherence tomography and ultra-wide-field autofluorescence imaging are the useful tools to understand the changes in peripheral retinal lesions Azusa Fujikawa; Kiyoshi Suzuma; Kanako Yamada; Daisuke Inoue; Takashi Kitaoka View Presentation 3597 - D0326. A comparison of spectral domain optical coherence tomography and multifocal electroretinography findings in hydroxychloroquine retinopathy Mark E. Seamone; Katherine Milton; Micheline C. Deschenes; Michael Fielden; Amin Kherani; R Geoff Williams View Presentation 3598 - D0327. Progression of Atrophy Following Intravitreal anti-VEGF for Exudative AMD Kyung Hoon Seo; Seung Won Lee; Moo Sang Kim; Seung-Young Yu; Hyung-Woo Kwak View Presentation 3599 - D0328. “En face” OCT for retreatment indications during follow up of Vascularized Pigment Epithelium Detachment in Exudative Age related Macular Degeneration Gabriel J. Coscas; Florence Coscas; Eric H. Souied View Presentation 3600 - D0329. Retinal thickness and volume measured with the enhanced depth imaging optical coherence tomography in normal eyes and in eyes with chorioretinal disorders Sung Yong Park; Sung Min Kim; Yun-Mi Song; Joohon Sung; Don-Il Ham View Presentation 3601 - D0330. Outer retinal structure in OCT and microperimetry SUQIN YU View Presentation 3602 - D0331. Predicting the Visual Acuity of Patients with Diabetic Macular Edema from the Measured Disruption Status of External Limiting Membrane on the SD-OCT Scan Hrvoje Bogunovic; Michael D. Abramoff; Elliott H. Sohn; Milan Sonka View Presentation 3603 - D0332. Test-retest variability of microperimetry in patients with type 2 idiopathic Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 137 sur 222 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM macular telangiectasia Evan N. Wong; Ian Constable; Fred K. Chen View Presentation 3604 - D0333. Comparison of main OCT features of Type 2 macular telangiectasia in time- and spectral domain OCTs Tunde Peto; Irene Leung; Ferenc B. Sallo; Daniela Florea; Alan C. Bird View Presentation 3605 - D0334. A comparison of microperimetry parameters derived from the CenterVue MAIA and Nidek MP1S instruments in subjects with type 2 idiopathic macular telangiectasia (MacTel) Fred K. Chen; Ian Constable; Evan N. Wong View Presentation 3606 - D0335. Microscopic Retinal Structure in Macular Telangiectasia Austin Roorda; Brandon J. Lujan; Kavitha Ratnam; Vincent J. Liu; Johnny Tam; Steven D. Schwartz; Andrew Kaines; Paul S. Bernstein; Yuhua Zhang; Jacque L. Duncan View Presentation 3607 - D0336. Acute Macular Neuroretinopathy: New Insights into Pathogenesis and Association with Retinal Capillary Ischemia Ehsan Rahimy; David Sarraf; Amani A. Fawzi; Elliott H. Sohn; Irene A. Barbazetto; David N. Zacks; Robert A. Mittra; Sarah Mrejen; Naomi R. Goldberg; K Bailey Freund View Presentation 3608 - D0337. Comparison of retinal layer thickness of normal eyes and eyes with diabetic macular edema receiving ranibizumab Zubir S. Rentiya; Yasir J. Sepah; Mohamed A. Ibrahim; Mohammad A. Sadiq; Muhammad Hassan; Saleema Kherani; Hyun Soo Jang; Raafay Sophie; Diana V. Do; Quan Dong Nguyen View Presentation 3609 - D0338. En-face optical coherence tomography of ocular toxoplasmosis Andre C. Romano; Rubens Belfort View Presentation 3610 - D0339. Foveal Pit Dimensions in Myopia Rhett Stroupe; Nancy J. Coletta View Presentation 3611 - D0340. Peripapillary And Macular Changes Detected by SD OCT in Eyes With High Myopia Leila El Matri; Ahmed Chebil; Besma Ben Achour; Yosra Falfoul; Mejda Bouladi View Presentation 3612 - D0341. Measuring Macula Hole Size on Optical Coherence Tomography; Inter and Intra Observer Agreement Philip J. Banerjee; Mostafa A. Elgohary; Louisa Wickham; David G. Charteris View Presentation 3613 - D0342. Optical coherence tomography findings as prognostic factor in idiopathic epiretinal membrane surgery Itzel Espinosa; Adriana Saucedo; Abel Ramírez View Presentation 3614 - D0343. Analysis of Epiretinal Membranes Using Spectral Domain Optical Coherence Tomography (OCT) Ajay E. Kuriyan; Delia DeBuc; William E. Smiddy View Presentation 3615 - D0344. Correlation of Preoperative Retinal Pigment Epithelium Status with Foveal Microstructure in Repaired Macular Holes Michele Reibaldi; Teresio Avitabile; Antonio Longo; Franco Marco Livio; Vincenza Bonfiglio; SALVATORE FARO; Francesca Viti; Andrea Saitta; Michele Nicolai; Cesare Mariotti View Presentation 3616 - D0345. Acute central retinal vein occlusion followed by disc edema: a frequent cause of macular thickening without macular edema Feng Liang; Jean François Girmens; Jose A. Sahel; Michel Paques View Presentation 3617 - D0346. Assessment of Cirrus™ OCT Registration in Macular Edema from Diabetes or Retinal Vein Occlusion Voraporn Chaikitmongkol; Mary K. Durbin; Susan B. Bressler; Neil M. Bressler View Presentation 3618 - D0347. Optical Coherence Tomography Predicts Visual Outcome after Acute Retinal Ischemia due to Central Retinal Vein Occlusion Suk Ho Byeon; Jae Sang Ko View Presentation 3619 - D0348. OCT Analysis of Recurrent Fluid after Intravitreal Therapy for Macula Edema secondary to Central Retinal Vein Occlusion stephen holland; David G. Dodwell View Presentation 3620 - D0349. Extrafoveal Changes Following Intravitreal Bevacizumab Injections for Macular Edema Secondary to Branch Retinal Vein Occlusion: A mfERG and OCT Study Young-Hoon Ohn; Joo Hyun; Saemi Park; Tae Kwann Park View Presentation 3621 - D0350. Improved repeatability of retinal thickness measurements using LSO image-based retinal tracking Jennifer Hu; Cornelia B. Gottlieb; Daniel Barajas; Cullen J. Barnett; Tamera Schoenholz; Mary K. Durbin; Hari Iyer; Srinivas Sadda View Presentation 3622 - D0351. Retinal thickness with posterior pole analysis and its association with axial length and body height Takehiro Yamashita; Yuya Kii; Minoru Tanaka; Kumiko Nakao; Taiji Sakamoto View Presentation 3623 - D0352. Statistical correlation analysis between the retinal layer intensity ratios, the quality of the image, and the subject age based on 3D OCT Images Xinjian Chen; Ping Hou; Chao Jin; Weifang Zhu; Fei Shi; Haoyu Chen View Presentation 3624 - D0353. A Comparison of Short-Wavelength (488nm) and Near-infrared (787nm) Autofluorescence in Stargardt’s Disease Winston Lee; Tobias Duncker; Francois C. Delori; Rando Allikmets; Janet R. Sparrow View Presentation 3625 - D0354. Correlation of functional and morphological data in Stargardt’s disease Birgit Lorenz; Susann Stieger; Wadim Bowl; Knut Stieger View Presentation 3626 - D0355. The Value of Retinal Imaging and Functional Testing of Patients with Stargardt Disease Robert Chun; Frederick T. Collison; Michele May; Gerald A. Fishman View Presentation 3627 - D0356. Outer Retinal Structure Following Closed Globe Blunt Ocular Trauma John Flatter; Michael Dubow; Ravi S. Singh; Nishit Shah; Scott Robison; David V. Weinberg; Kimberly E. Stepien; Alfredo Dubra; Richard B. Rosen; Joseph Carroll View Presentation 3628 - D0357. Relationship between Dry Retinal Volume and Visual Acuity in Cystoid Macular Edema Muneeswar Gupta Nittala; Zhihong Hu; Srinivas R. Sadda View Presentation 3629 - D0358. Best Frames Selection and Montaging in Wide-field ROP Images Alfredo Ruggeri; Enea Poletti View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 138 sur 222 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 3630 - D0359. Macular Retinal Thickness in Moderately to Late Preterm School Aged Children Lina H. Raffa; Jovanna Dahlgren; Ann-Katrine Karlsson; Marita A. Gronlund View Presentation 3631 - D0360. Applications of Posterior Segment Optical Coherence Tomography (OCT) in Pediatric Ophthalmology Sharel C. Ongchin; Dawn A. Sim; Rebecca Smith; Pearse A. Keane; Dhanes Thomas View Presentation 3632 - D0361. RETINAL OPTICAL COHERENCE TOMOGRAPHY IN SICKLE CELL DISEASE Vasco T. Bravo-Filho; Fabiana B. Vilar; Thayze Martins; Silvio De Biase; João L. Andrade; Aderson S. Araújo; Tiago E. Arantes View Presentation 3633 - D0362. Retinal Thickness, Retinal Point Sensitivity and Inner Segment/Outer Segment Photoreceptor (IS/OS) Status after Treatment with Ranibizumab in Patients with Diabetic Macular Edema Millena G. Bittencourt; Daniel A. Ferraz; Jithin Yohanan; Owhofasa O. Agbedia; Mohammad A. Sadiq; Yasir J. Sepah; Mohamed A. Ibrahim; Raafay Sophie; Mostafa Hanout; Quan Dong Nguyen View Presentation 3634 - D0363. The cone outer segment termination (COST) line appears abnormal on OCT scans of patients with stationary and progressive forms of cone dysfunction Ari D. Schuman; Rithambara Ramachandran; Xian Zhang; David G. Birch; Donald C. Hood View Presentation 3635 - D0364. RETICULAR PATTERN DYSTROPHY: A SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY ANALYSIS Jennyfer Zerbib; Giuseppe Querques; Nathalie Massamba; Nathalie Puche; Julien Tilleul; Franck Lalloum; Mayer Srour; Eric H. Souied View Presentation 3636 - D0365. Prevalence and Associations of Incomplete Posterior Vitreous Detachment in Adult Chinese: the Beijing Eye Study Lei Shao; Wen Bin Wei View Presentation 3637 - D0366. Depth Resolved Enface Imaging of Inner Retinal Pathologies and Photoreceptor Integrity in Diabetic Retinopathy Andrew W. Francis; Justin Wanek; Jennifer I. Lim; Mahnaz Shahidi View Presentation 3638 - D0367. Retinal Edema and Orbital Blood Flow in Preeclampsia Madlene Holmqvist; Ingemar C. Gustafsson; Per Wollmer; Stefan R. Hansson; Patrik Schatz View Presentation 350. Strabismus: Detection and Quality of Life Moderator(s): Jonathan Holmes (Mayo Clinic) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 3639 - D0384. Factors related to strabismus decompensation after prolonged stability Eldad Adler; Yoonsang Kim; R Michael Siatkowski View Presentation 3640 - D0385. Clinical features and surgical outcome of strabismus in periventricular leukomalacia Hee-Young Choi; Jaeho Jung View Presentation 3641 - D0386. Surgical Outcomes of Intermittent Exotropia with a High Accommodation Convergence-Accommodation Ratio Hwan Heo; Mi Sun Sung; Sang Woo Park View Presentation 3642 - D0387. What Magnitude of Non-diplopic Strabismus Affects Health-Related Quality of Life? David A. Leske; Sarah R. Hatt; Laura Liebermann; Jonathan M. Holmes View Presentation 3643 - D0388. Specific Aspects of Function-Related Quality of Life Improvement in NonDiplopic Patients After Strabismus Surgery Laura Liebermann; Sarah R. Hatt; David A. Leske; Jonathan M. Holmes View Presentation 3644 - D0389. Status of quality of life in adult strabismus with corrective surgery: the long-term results Xinping Yu View Presentation 3645 - D0390. Principal component analysis of both AS-20 and A&SQ questionnaires in 110 subjects of the historic Waterland cohort Huibert J. Simonsz; Elizabeth S. van de Graaf; Joost Felius; Gerard Borsboom; Hendrikus Kelderman View Presentation 3646 - D0391. Clinical Characteristics and Natural History of Convergence Insufficiency Rafif Ghadban; Brian Mohney; Jennifer Martinez-Thompson View Presentation 3647 - D0392. Predictibility of relaxation test and eye position under general anesthesia in strabismus Solange Milazzo; Mounir Benzerroug; Dominique Bremond-Gignac View Presentation 3648 - D0393. Anisometropic Astigmatism in Superior Oblique Palsy Alexandra O. Apkarian; Julie Shelton; Sudha Nallasamy View Presentation 3649 - D0394. Wavelength dependence of the Brückner red eye effect Johan van Jole; Robbert J. van den Berg; Annelou van Donkelaar; Julia van Dronkelaar; Matthijs J. De Groot; Joris Coppens; Tos TJM Berendschot; Thomas J. Van Den Berg; Huibert J. Simonsz View Presentation 3650 - D0395. Accuracy of Double Maddox Rod Testing with Variable Prism Induced Hypertropia Justin D. Marsh; Bethany Markowitz; Andrew E. Hack View Presentation 351. Nanotechnology and Regenerative Medicine Group: Minimally Invasive Biometric Technology as a Means to Improve Detection, Understanding, and Treatment of Ocular Disease Moderator(s): Victor Elner (Univ of Michigan-Kellogg Eye Ctr), Austin Roorda (University of California, Berkeley) and Robert Ritch (New York Eye & Ear Infirmary) 1:00 PM - 2:30 PM; TCC 305 1:00 PM - 1:15 PM 1:15 PM - 1:30 PM 1:30 PM - 1:45 PM View Session Details View Session Details Mitochondrial Imaging in Diabetic Retinopathy and Age-Related Macular Degeneration Victor M. Elner View Presentation Use of Nanotechnology for Diagnosis and Treatment of Diabetic Retinopathy Gerard A. Lutty View Presentation Use of Adaptive Optics Scanning Laser Ophthalmoscopy and OCT to Monitor Photoreceptors in Retinal Degenerative Diseases Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 139 sur 222 1:45 PM - 2:00 PM 2:00 PM - 2:15 PM 2:15 PM - 2:30 PM Jacque L. Duncan View Presentation Clinical experience in using Triggerfish® for the recording of the 24-hour IOP pattern Rene Goedkoop View Presentation OCT-Based ONH and Retinal Blood Flow for Early Diagnosis of Glaucoma David Huang View Presentation Panel Discussion Include in Itinerary Include in Itinerary Include in Itinerary Showing 1 - 50 of 81 See More... WEDNESDAY, MAY 08, 2013 401. Biochemistry of Glaucoma Moderator(s): Stanislav Tomarev (National Eye Institute) and Ernst Tamm (University of Regensburg) 8:30 AM - 10:15 AM; 6A View Session Details 4002. Myocilin affects differentiation of oligodendrocytes and regulates myelination of the optic nerve via Lingo-1/RhoA signaling Stanislav I. Tomarev; Heung Sun Kwon; Naoki Nakaya; Mones S. Abu-Asab View Presentation 8:45 AM - 9:00 AM 4003. Genomewide DNA methylation analysis of human trabecular meshwork cells with dexamethasone stimulation Akira Matsuda; Nobuyuki Ebihara; Akira Murakami View Presentation 9:00 AM - 9:15 AM 4004. Stabilization of Myocilin with Small Molecules Prevents Its Aggregation Raquel L. Lieberman; Shannon E. Hill; Rebecca K. Donegan; Katherine C. Turnage View Presentation 9:15 AM - 9:30 AM 4005. PGC-1alpha Signaling Regulates Retinal Ganglion Cell Injury Responses And Atrocyte Reactivity Jeremy M. Sivak; Xiaoxin Guo; Shirin Dason; Adrian Nahirny View Presentation 9:30 AM - 9:45 AM 4006. Subcellular mislocalization and loss of function of mutant Gpnmb proteins Alexander C. Theos View Presentation 9:45 AM - 10:00 AM 4007. Cochlin and phosphatidylcholines interact with SLC44A2 channel on the trabecular meshwork cells Sanjoy K. Bhattacharya; Mitchell Martinez; Ayman Aljohani; Richard K. Lee View Presentation 4008. Disruption of the homeostatic balance between TGF-β and BMPs in the outflow 10:00 AM - 10:15 tissues of the CTGF-based Glaucoma mouse model AM Sabrina Kuespert; Ernst R. Tamm; Rudolf Fuchshofer View Presentation 8:30 AM - 8:45 AM 402. New Ideas Moderator(s): Jonathan Crowston (Ctr for Eye Research Australia), Peng Khaw (NIHR Biomed Res Centre Moorfields UCL Inst Ophth) and George Cioffi (Columbia Univ Med Center) 8:30 AM - 10:15 AM; 6B View Session Details 4009. Glucose-induced Temporary Visual Recovery in Human Glaucoma: A Prospective, Double-blind, Randomised Study Robert J. Casson; Glyn Chidlow; Andreas Ebneter; Guoge Han; Jolly Gilhotra; John P. Wood View Presentation 8:45 AM - 9:00 AM 4010. Radiation Treatment Does Not Protect the Rat Optic Nerve from Elevated Intraocular Pressure (IOP)-Induced Injury Elaine C. Johnson; William Cepurna; John C. Morrison View Presentation 9:00 AM - 9:15 AM 4011. Estrogen Pathway Polymorphisms in Relation to Primary Open Angle Glaucoma: A Gender-Specific Analysis from Patients in the United States Louis R. Pasquale; Stephanie Loomis; Brian Yaspan; Jae H. Kang; Robert N. Weinreb; Julia E. Richards; Michael A. Hauser; Jonathan L. Haines; Janey L. Wiggs View Presentation 9:15 AM - 9:30 AM 4012. A Novel Device for Clinical Measurement of Corneal Elasticity Christopher K. Leung; Cong Ye; Match Ko; Leo Leung; David Lam View Presentation 9:30 AM - 9:45 AM 4013. A Potential Role for the Hypothalamic Orexin System in Mediating Intraocular Pressure Fluctuations Brian C. Samuels; Nathan Hammes; Philip L. Johnson; Anantha Shekhar View Presentation 9:45 AM - 10:00 AM 4014. Pulse-induced Trabecular Meshwork (TM) Movement in Humans: Characterization by Phase-sensitive OCT (PhS-OCT) Murray A. Johnstone; Peng Li; Tueng T. Shen; Ruikang K. Wang View Presentation 4015. A quantitative approach to the analysis of visual field defect location and its 10:00 AM - 10:15 relationship to measures of disability AM Michael V. Boland; Pradeep Y. Ramulu; Karun S. Arora; Joan L. Jefferys; David S. Friedman View Presentation 8:30 AM - 8:45 AM 403. Retinitis Pigmentosa II Moderator(s): Yasuhiro Ikeda (Kyushu University) and Ava Bittner (Johns Hopkins Univ.) 8:30 AM - 10:15 AM; 6C 8:30 AM - 8:45 AM 8:45 AM - 9:00 AM 9:00 AM - 9:15 AM 9:15 AM - 9:30 AM View Session Details 4016. Long-term efficacy and safety of treatment of retinitis pigmentosa with valproic acid Christine N. Kay; Sheena Bhalla View Presentation 4017. Visual Function Improvements following Electroacupuncture for Retinitis Pigmentosa Ava K. Bittner; Jeff Gould; Collin Rozanski; Andy Rosenfarb; Marius R. DeJong; Alexandra Benavente-Perez; Gislin Dagnelie View Presentation 4018. Evaluation of peripheral retinal vasculitis in retinitis pigmentosa using wide-field fluorescein angiography Matthew B. Kaufman; Carlos A. Medina-Mendez; Thomas R. Friberg; Andrew W. Eller View Presentation 4019. Inheritance of Retinitis Pigmentosa: Update in the Era of Genetic Testing Kari E. Branham; Jillian Huang; Kanishka T. Jayasundera; John R. Heckenlively View Presentation Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 140 sur 222 4020. Ultra wide-field autofluorescence is useful to evauluate residual retinal functions in patients with Retinitis Pigmentosa Shuntaro Ogura; Tsutomu Yasukawa; Munenori Yoshida; Yuichiro Ogura View Presentation 9:45 AM - 10:00 AM 4021. Recombinant Human Nerve Growth Factor Protects Photoreceptor Degeneration in a Rat Model of Inherited Retinitis Pigmentosa Luigi Aloe; Patrizia Bianchi; Maria Luisa Rocco; Alessandra Micera; Alessandro Lambiase; Stefano Bonini View Presentation 4022. Nonsyndromic RP Due to BBS2 Mutations 10:00 AM - 10:15 Meghan J. Marino; Gayle J. Pauer; John Chiang; Stephanie A. Hagstrom; Elias I. AM Traboulsi View Presentation 9:30 AM - 9:45 AM 404. DR: Therapeutic Effects Moderator(s): Peter Campochiaro (Johns Hopkins Wilmer Eye Inst) and Rajendra Apte (Washington Univ - St Louis) 8:30 AM - 10:15 AM; 6E View Session Details 4023. Intravitreal ranibizumab (RBZ) suppresses posterior retinal nonperfusion (RNP) in patients with diabetic macular edema (DME) Peter A. Campochiaro; Charles Wykoff; Dafeng Chen; Howard Shapiro; Jason S. Ehrlich; Roman Rubio View Presentation 8:45 AM - 9:00 AM 4024. Intensive Diabetes Therapy Reduces Ocular Surgeries in Patients with Type 1 Diabetes: twenty-eight year followup of the Diabetes Control and Complications Trial / Epidemiology of Diabetes Interventions and Complications study (DCCT/EDIC) Lloyd P. Aiello; Wanjie Sun; Patricia A. Cleary; John M. Lachin; Sapna Gangaputra; Ronald Klein; Arup Das; Szilard Kiss; Amitha Domalpally; Ronald P. Danis View Presentation 4025. Canadian PhIIIb study: ranibizumab combination/monotherapy in visual 9:00 AM - 9:15 AM impairment due to DME: Preliminary Analysis Thomas Sheidow; Alan R. Berger; Frederica deTakacsy; Ruihong’ Li; Bonita Rehel; AnneSophie Courseau View Presentation 9:15 AM - 9:30 AM 4026. Baseline Predictors of improvement in self-reported visual function following treatment with ranibizumab in patients with diabetic macular edema Rohit Varma; Neil M. Bressler; Chantal Dolan; Linda Yau; James F. Ward; Shoshana Colman View Presentation 9:30 AM - 9:45 AM 4027. Effect of Statins and Diabetes Therapy (Oral Hypoglycemics and Insulin) on the Outcomes of Patients Treated with Ranibizumab and/or Laser Therapy Mohammad A. Sadiq; Muhammad Hassan; Yasir J. Sepah; Graeme K. Loh; Saleema Kherani; Mostafa Hanout; Rachel E. Annam; Mehreen Ansari; Diana V. Do; Quan Dong Nguyen View Presentation 9:45 AM - 10:00 AM 4028. Effects of Intravitreal Ranibizumab on Diabetic Retinopathy Severity: 36 Month Data from the RISE and RIDE Phase III Trials Jason S. Ehrlich; Amitha Domalpally; Linda Yau; J J. Hopkins; Michael S. Ip View Presentation 4029. RELIGHT - Ranibizumab treatment of diabetic macular oedema with bimonthly 10:00 AM - 10:15 monitoring after a phase of initial Treatment AM Ian A. Pearce View Presentation 8:30 AM - 8:45 AM 405. Host Responses to Ocular Herpesvirus Infection - What Have We Learned and What Is the Future Direction? - Minisymposium Moderator(s): Daniel Carr (Univ of Oklahoma Hlth Sci Ctr) and Barry Rouse (Univ of Tennessee Coll of Vet Med) 8:30 AM - 10:15 AM; 606/607 View Session Details 4030. Insights into Natural History of HSV Infections in the Era of Changing Epidemiology Anna Wald View Presentation 9:00 AM - 9:20 AM 4031. Herpes Simplex Virus Evasion of Host Immunity and the Autophagy Response David A. Leib View Presentation 9:20 AM - 9:40 AM 4032. Chronic Murine Cytomegalovirus Infection results in more severe Experimental Choroidal Neovascularization Richard D. Dix View Presentation 9:40 AM - 10:00 AM 4033. Pathogenesis of Herpes Stromal Keratitis - A Focus on Corneal Neovascularization Barry T. Rouse View Presentation 4034. Discussion 10:00 AM - 10:15 Todd P. Margolis AM View Presentation 8:30 AM - 9:00 AM 406. Myopia and Emmetropization Moderator(s): Frank Schaeffel (Ophthalmic Research Institute) and Chi-ho To (Hong Kong Polytechnic Univ) 8:30 AM - 10:15 AM; 608 View Session Details 4035. Distribution and Determinants of Eye Size and Shape in Newborn Children: a Magnetic Resonance Imaging Analysis Laurence S. Lim; Pei Ting Tan; Gim Hong Chong; Yap-Seng Chong; Marielle V. Fortier; Peter Gluckman; Seang-Mei Saw; Anqi Qiu View Presentation 4036. Central retinal thickness and axial length in the Copenhagen Child Cohort 2000 8:45 AM - 9:00 AM study: data from 432 11-year-old children Xiao Q. Li; Michael Larsen; Inger C. Munch View Presentation 9:00 AM - 9:15 AM 4037. Neurochemical Ablation of Peripheral Glucagonergic Amacrine Cells in the Chick Retina and its Effects on Axial Eye Growth and Refractive Error Diane Nava; Alice Chang; Lisa A. Ostrin; Zhi Chen; Christine F. Wildsoet View Presentation 9:15 AM - 9:30 AM 4038. Ocular growth guided by dual focal fresnel lenses requires an intact optic nerve Sally A. McFadden; Dennis Y. Tse; Chi-ho To; Christine F. Wildsoet View Presentation 9:30 AM - 9:45 AM 4039. Effects of Long-Wavelength-Pass Filters on Refractive Development in Rhesus Monkeys Earl L. Smith; Li-Fang Hung; Baskar Arumugam; Juan Huang; Maureen Neitz; Jay Neitz View Presentation 9:45 AM - 10:00 AM 4040. The role of central retina in chicks during form deprivation myopia Jianchao wang; Rachel K. M Chun; K. k Li; Quan Liu; Chiho To View Presentation 4041. Photoreceptor Outer Retinal Function as the Primary Controller of Ocular Growth 10:00 AM - 10:15 David P. Crewther; Sarah N. Kiely; Melanie J. Murphy; Nina Riddell; Sheila G. Crewther AM 8:30 AM - 8:45 AM Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 141 sur 222 View Presentation 407. Cell Biology Impacts Lens Function Moderator(s): Marc Kantorow (Florida Atlantic University) and A Menko (Thomas Jefferson University) 8:30 AM - 10:15 AM; 609 View Session Details 4042. JNK inactivation suppresses mTOR (Mammalian Target of Rapamycin) pathway to induce loss of nuclei and organelles in the lens through Autophagy Subhasree Basu; Suren Rajakaruna; Beverly . Reyes; Elisabeth J. Van Bockstaele; A S. Menko View Presentation 4043. Autophagy mediates mitochondrial degradation in the developing and adult eye 8:45 AM - 9:00 AM lens Marc Kantorow; Daniel Chauss; Ashik Mohamed; Kurt Gilliland; Lisa A. Brennan; M J. Costello View Presentation 9:00 AM - 9:15 AM 4044. Loss of Pten Rescues Akt Phosphorylation, Apoptosis and Size in Fgfr2 Deficient Lenses Blake R. Chaffee; Melissa R. Leonard; Brad D. Wagner; Michael L. Robinson View Presentation 9:15 AM - 9:30 AM 4045. Role of Birc7 in the Mouse Lens Alicia De Maria; Steven Bassnett View Presentation 9:30 AM - 9:45 AM 4046. The Optical Quality of Inhibitor-Treated Avian Crystalline Lenses Gah-Jone Won; Vivian Choh View Presentation 9:45 AM - 10:00 AM 4047. Estimation of Ciliary Muscle Forces Required to Induce Corneal Deformation Robert P. Wilkes; Matthew A. Reilly View Presentation 4048. Linking the optical properties of the lens to its cellular physiology: a multimodal 10:00 AM - 10:15 imaging and modelling approach AM Ehsan Vaghefi Rezaei; Andy Kim; Paul J. Donaldson View Presentation 8:30 AM - 8:45 AM 408. Differentiation of Stem and iPS Cells Moderator(s): Jason Meyer (Indiana Univ- Purdue Univ Indianapolis) and G Astrid Limb (UCL Institute of Ophthalmology) 8:30 AM - 10:15 AM; 611-614 View Session Details 4049. MITF regulation of early cell fate in a human embryonic stem cell model of retinal development Elizabeth E. Capowski; Joseph Simonett; Eric Clark; Lynda S. Wright; Isabel Pinilla Lozano; Joe Phillips; Kyle Wallace; David M. Gamm View Presentation 4050. Simplified and Efficient Generation of Photoreceptors from Human Pleuripotent 8:45 AM - 9:00 AM Stem Cells Joo Young Shin; Hyeong Gon Yu View Presentation 9:00 AM - 9:15 AM 4051. Improving Human RPE Differentiation from iPS Cells: Lessons from Mouse Eye Development Kapil Bharti; Janine Davis; Barbara Corneo; Qin Wan; Kiyoharu J. Miyagishima; Sally Temple; Sheldon S. Miller View Presentation 9:15 AM - 9:30 AM 4052. Investigating the role of VSX2 (CHX10) in human retinogenesis using iPS cells Joe Phillips; Enio Perez; Kyle Wallace; Jessica M. Martin; Ruchira Singh; Elizabeth E. Capowski; Lynda S. Wright; Eric Clark; E. F. Percin; David M. Gamm View Presentation 9:30 AM - 9:45 AM 4053. Differentiation of Human Protein Induced Pluripotent Stem Cells (piPS) Towards a Retinal Pigment Epithelium (RPE) Fate Jie Gong; Mark A. Fields; Lucian V. Del Priore View Presentation 9:45 AM - 10:00 AM 4054. Investigating the pathophysiology of USH2A associated retinal degeneration with patient specific iPSCs Budd A. Tucker; Robert F. Mullins; Kristin R. Anfinson; Louisa M. Affatigato; Jennifer A. Halder; Peter M. Brzeskiewicz; Edwin M. Stone View Presentation 4055. Differentiation of iPS-RPE cells from a patient with clinical anophthalmia 10:00 AM - 10:15 Amanda-Jayne F. Carr; Lena Ho; Li Li Chen; Grace Selva Raj; Anthony A. Vugler; AM Mohammad A. Shboul; Alan Colman; Bruno Reversade; Peter J. Coffey View Presentation 8:30 AM - 8:45 AM 409. Purine Signaling in the Eye: Role in Health and Disease - Minisymposium Moderator(s): Julie Sanderson (University of East Anglia), Claire Mitchell (University of Pennsylvania Library) and Claudio Bucolo (University of Catania) 8:30 AM - 10:15 AM; 618-620 View Session Details 4056. Introduction to Purine Signaling Julie Sanderson View Presentation 8:45 AM - 9:00 AM 4057. Purine Signaling in the Trabecular Meshwork: A Regulator of Intraocular Pressure Mortimer M. Civan View Presentation 9:00 AM - 9:15 AM 4058. Purinergic Receptors in Lacrimal Gland Health and Dry Eye Disease Darlene A. Dartt View Presentation 9:15 AM - 9:30 AM 4059. TRPV4 and Hemichannels Cooperate to Play a Critical Role in Purine Signaling in the Lens Nicholas A. Delamere View Presentation 9:30 AM - 9:45 AM 4060. Purine Signaling in Müller Cells During Development and in the Adult Retina in Health and Disease Antje Grosche View Presentation 9:45 AM - 10:00 AM 4061. Purinergic Signaling in Retinal Processing Thomas E. Salt View Presentation 4062. Purines and Low Grade Inflammation at Either End of the Retina; ATP and 10:00 AM - 10:15 Cytokines in Both RGCs and RPE AM Claire H. Mitchell View Presentation 8:30 AM - 8:45 AM 410. Spatial Vision, Visual Psychophysics and Aging II Moderator(s): Joanne Wood (Queensland Univ of Technology) and Heidi Hofer (University of Houston) 8:30 AM - 10:15 AM; TCC LL 4/5 8:30 AM - 8:45 AM View Session Details 4063. Two-point detection and appearance in the absence of higher order aberrations Heidi J. Hofer; Darren E. Koenig Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 142 sur 222 View Presentation 4064. A Comparison of Acuity and Cone Density in the Temporal Retina Nancy J. Coletta; Toco Y. Chui; Ann E. Elsner View Presentation 9:00 AM - 9:15 AM 4065. Age-related variation in foveal, parafoveal and peripheral spatial suppression Rigmor C. Baraas; Craig Aaen-Stockdale; Stuart J. Gilson View Presentation 9:15 AM - 9:30 AM 4066. Heterochromatic Modulation Photometry can be used to measure Macular Pigment Optical Density Cord R. Huchzermeyer; Juliane Schlomberg; Ulrich Welge-Lüssen; Tos TJM Berendschot; Jan J. Kremers View Presentation 9:30 AM - 9:45 AM 4067. Comparability of Visual Performance of Individuals with Low Vision in Real and Virtual Street Intersections Lei Liu; Ellen L. Bowman View Presentation 9:45 AM - 10:00 AM 4068. Optical quality and subjective judgments of blur under pure simultaneous vision Carlos Dorronsoro; Aiswaryah Radhakrishnan; Lucie Sawides; Susana Marcos View Presentation 8:45 AM - 9:00 AM 411. Keratoconus and Biomechanics Moderator(s): Shukti Chakravarti (Johns Hopkins Sch of Medicine) 8:30 AM - 10:15 AM; TCC 303 View Session Details 4069. Mutations in the zinc finger protein gene, ZNF469 contribute to the pathogenesis of keratoconus Andrea L. Vincent; Charlotte Jordan; Bryan Hay; Amanda J. Richards; Charles N. McGhee View Presentation 8:45 AM - 9:00 AM 4070. Matrix Metalloproteinase-9 drives disease progression of Keratoconus ashwini ranganath; Rohit Shetty; Sharon D'Souza; Kareeshma Wadia; Debashish Das; Arkasubhra Ghosh View Presentation 9:00 AM - 9:15 AM 4071. Novel proteins and metabolites for the identification of Keratoconus disease Dimitrios Karamichos; Jesper Hjortdal; Audrey E. Hutcheon; John M. Asara; James D. Zieske View Presentation 4072. Evaluation of transcorneal iontophoresis of riboflavin for corneal collagen cross9:15 AM - 9:30 AM linking Alejandro Arboleda; Laura Kowalczuk; Michèle Savoldelli; Christophe Klein; Sophia Ladraa; Jean-Marie A. Parel; Francine F. Behar-Cohen View Presentation 9:30 AM - 9:45 AM 4073. Corneal biomechanical properties in corneal collagen cross-linking (CXL) at high fluences Arthur Hammer; Olivier Richoz; David Tabibian; Florence Hoogewoud; Farhad Hafezi View Presentation 9:45 AM - 10:00 AM 4074. Soluble collagen protects the corneal fibrils during riboflavin crosslinking Marcos Garza-Madrid; Jennifer Elisseeff View Presentation 4075. Brillouin microscopy of collagen crosslinking: non-contact depth-dependent 10:00 AM - 10:15 analysis of corneal elastic modulus AM Giuliano Scarcelli; Sabine Kling; Elena Quijano; Roberto Pineda; Susana Marcos; Seok H. Yun View Presentation 8:30 AM - 8:45 AM 412. Photoreceptors: Structure, Transduction, Signaling Moderator(s): Marie Burns (Univ of California-Davis) and Wolfgang Baehr (University of Utah) 8:30 AM - 10:15 AM; TCC 304 View Session Details 4076. Modulating the phototransduction cascade with small molecules Tomoki Isayama; Junchao Wu; Sadaharu Miyazono; Vanessa Lee; Emily S. Levine; Elina Makino; Anita L. Zimmerman; Clint L. Makino View Presentation 8:45 AM - 9:00 AM 4077. Under-expression of GAP proteins: Effect on Mouse Rod Response Decay Gordon L. Fain; Michael L. Woodruff; Ching-Kang J. Chen View Presentation 9:00 AM - 9:15 AM 4078. Light-induced translocation of RGS9-1 and Gβ5L in Mouse Rod Photoreceptors You-Wei Peng; Mei Tian; Marisa L. Zallocchi; Weimin Wang; Ching-Kang J. Chen; Krzysztof Palczewski; Dominic E. Cosgrove View Presentation 9:15 AM - 9:30 AM 4079. Complete protein composition of the photoreceptor disc identified by label-free quantitative proteomics Nikolai P. Skiba; Vadim Y. Arshavsky View Presentation 9:30 AM - 9:45 AM 4080. Molecular Function of Peripherin-2/rds for Photoreceptor Membrane Structure Andrew F. Goldberg; Nidhi Khattree; Linda M. Ritter View Presentation 9:45 AM - 10:00 AM 4081. Bleach-Induced Desensitization and Response Compression of the Photocurrent and Photovoltage in Mouse Rods Johan Pahlberg; Rikard Frederiksen; Kiyoharu J. Miyagishima; Soile Nymark; Alapakkam P. Sampath; M C. Cornwall View Presentation 4082. Phosphoinositides and membrane trafficking in zebrafish cone inner segments 10:00 AM - 10:15 Sara Hayden; Susan E. Brockerhoff AM View Presentation 8:30 AM - 8:45 AM 413. AMD II, RE Moderator(s): David Hinton (Keck School of Medicine USC) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 4083 - A0001. Pars Plana Vitrectomy, Subretinal Injection of Recombinant Tissue Plasminogen Activator and Intraocular Gas Tamponade for Thick Submacular Hemorrhage with Polypoidal Choroidal Vasculopathy Woohyok Chang; Chan Ho Cho; Min Sagong; Hyun Ju Oh; Jae Whi Park; Dong Geun Park; Mi Rae Kim; Won Mo Gu; Jun Hyuk Son View Presentation 4084 - A0002. The Effects of Docosahexaenoic Acid (DHA) Dietary Supplementation on Retinal Lipid Profile in a Mouse Model of Stargardt-like Macular Dystrophy (STGD3) Mandy Hong; Sharee Kuny; Rachel Bryant; Frederic Gaillard; Miyoung Suh; Yves Sauve View Presentation 4085 - A0003. In vivo Evaluation of Surface Modified Expanded-polytetrafluroethylene (ePTFE) Substrate as a Permanent Substrate for Cell Transplantation Shen Nian; Zhongjie Fu; Carl M. Sheridan; Victoria Kearns; Rachel Williams; Sai Hung David Wong; Krasimir Vasilev; Akash Bachhuka; Amy C. Lo; Wico W. Lai View Presentation 4086 - A0004. Prevalence of Subretinal Drusenoid Deposits in Age-Related Macular Degeneration with Newly Diagnosed Choroidal Neovascularization Sandrine A. Zweifel; Roman A. Rieder; Myrtha M. Kohler; Reto Gambon Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 143 sur 222 View Presentation 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 4087 - A0005. Autofluorescence and OCT of Retinal pigment epithelial tears Naoto Hanyuda; Taku Sato; Ryo Mukai; Shoji Kishi View Presentation 4088 - A0006. Anatomic patterns and clinical presentation of recurrence in ‘stable’ wet Age Related Macular Degeneration (AMD) patients Fani Zacharaki; Manju N. Chandran; Narendran Nair; Priyanga Vijayakumar; Geeta Menon View Presentation 4089 - A0007. Detection and Quantification of Autofluorescence Abnormalities in Patients with Neovascular Macular Degeneration using a Fully Automated Image Analysis Algorithm Kathryn L. Pepple; Qing Nie; Sally S. Ong; Scott W. Cousins View Presentation 4090 - A0008. Ranibizumab Leads to Regression or Elimination of Choroidal Neovascular Membranes in Most Eyes with AMD: A HARBOR Subanalysis Nikolas J. London; Paul E. Tornambe; Linda Yau; Jeffrey A. Nau; Lisa Tuomi View Presentation 4091 - A0009. Anti-VEGF Gene Therapy for Wet AMD: Phase I/II Safety and Pharmacology Results Elizabeth P. Rakoczy; May Lai; Cora Pierce; Aaron L. Magno; Richard Samulski; Thomas W. Chalberg; Mark S. Blumenkranz; Ian Constable View Presentation 4092 - A0010. Polypoidal choroidal vasculopathy in Caucasian patients Stephen Davis; Andreas Lauer; Christina J. Flaxel View Presentation 4093 - A0011. Baseline characteristics and response to intravitreal ranibizumab therapy for age-related macular degeneration Misa Suzuki; Norihiro Nagai; Kanako Izumi-Nagai; Hajime Shinoda; Takashi Koto; Atsuro Uchida; HIroshi Mochimaru; Kenya Yuki; Kazuo Tsubota; Yoko Ozawa View Presentation 4094 - A0012. Disease Activity in Disciform Scars due to Age-Related Macular Degeneration (AMD) Deborah Witkin; John B. Sanderson; Daniela Ferrara; Elias Reichel View Presentation 4095 - A0013. The Incidence of Neovascular Subtypes in Newly Diagnosed Wet AgeRelated Macular Degeneration Jesse J. Jung; Luna Xu; Roberto Gallego-Pinazo; Sarah Mrejen; Marcela Marsiglia; Sucharita Boddu; K Bailey Freund View Presentation 4096 - A0014. Choroidal thickness change following intravitreal bevacizumab therapy for wet age-related macular degeneration: Six months results Sharif Y. El Emam; Giulio Barteselli; Jay Chhablani; Su-Na Lee; Igor Kozak; Lingyun Cheng; William Freeman View Presentation 4097 - A0015. The Relationship of Choroidal Thickness to Scotopic Sensitivity in Agerelated Macular Degeneration (AMD) Karl G. Csaky; David G. Birch; Rosie Gelman; Joost Felius View Presentation 4098 - A0016. Choroidal Thickness following Anti-Vascular Endothelial Growth Factor Therapy for Neovascular Age-Related Macular Degeneration charlotte so; Zac Ravage View Presentation 4099 - A0017. CORRELATION BETWEEN CHANGES IN SUBFOVEAL CHOROIDAL THICKNESS AND 1-YEAR OUTCOMES OF RANIBIZUMAB THERAPY FOR POLYPOIDAL CHOROIDAL VASCULOPATHY Taiichi Hikichi; Hirokuni Kitamei; Shoko Shioya; Makoto Higuchi; Takuro Matsushita; Shoko Kosaka; Reiko Matsushita; Kimitaka Takami; Hideo Ohtsuka View Presentation 4100 - A0018. Axial Length and Subfoveal Choroidal Thickness in Individuals with Agerelated Macular Degeneration (AMD) Chih Ping Wang; Chien-Hsiung Lai; Jou Chen Huang; Chien Neng Kuo View Presentation 4101 - A0019. APE1/Ref-1 redox inhibitor APX3330 modulates choroidal endothelial cells by transcriptional regulation of NF-κB and STAT3 activity Xiaoxi Qiao; Yue Li; Xiuli Liu; Tongrong Zhou; Mark R. Kelley; Paul A. Edwards; Hua Gao View Presentation 4102 - A0020. Apolipoprotein mimetic Dual Domain Peptide reduces Neutral Lipid Deposits in murine Bruch's Membrane Armin Mohi; Salvatore Grisanti; Martin Rudolf View Presentation 4103 - A0021. Identification of Human Macular Tissue Antigens Recognized by Serum Auto-Antibodies (auto-Abs) in Patients with Age-Related Macular Degeneration (AMD) Nataliya I. Lenchik; Francesco Giorgianni; Sarka Beranova-Giorgianni; Ivan C. Gerling; Marko Z. Radic; Alessandro Iannaccone View Presentation 4104 - A0022. Early ocular lipid deposition in a mouse model of hyperlipidemia and atherosclerosis Michaela K. Mathews; Tatyana Albukh; Katherine E. Duncan View Presentation 4105 - A0023. The role of systemic infection and response to Ranibizumab therapy for Age Related Macular Degeneration (AMD) Charles O. Pierce; Marie Nelson; Jennifer Scott; Helen L. Griffiths; Natalee L. James; Heather A. Thomson; Angela J. Cree; Andrew J. Lotery View Presentation 4106 - A0024. Immunohistochemical analysis of primate drusen reveals homologous protein expression between monkey and human Trevor J. McGill; Laurie Renner; Alison R. Weiss; Kay D. Rittenhouse; Justin Lee; Joachim Fruebis; Marvin Sperling; Martha Neuringer View Presentation 4107 - A0025. A Pathway-based Genome-wide Analysis Yields Multi-locus AMD Associations in Genes Encoding JNK/MAPK Pathway Elements, Platelet Activation Triggers, and Targets of miR34 and HDAC1 John Paul P. SanGiovanni View Presentation 4108 - A0026. Minocycline protects retinal pigment epithelial cells from hypoxia Joanna DaCosta View Presentation 4109 - A0027. Dominantly Inherited Early Onset Maculopathy in Japanese Macaques: Drusen Progression Anda Cornea; Laurie Renner; Sawan Hurst; Trevor J. McGill; Mark E. Pennesi; Kay D. Rittenhouse; Marvin Sperling; Joachim Fruebis; Martha Neuringer View Presentation 4110 - A0028. Progression of Atrophic Macular Degeneration in Rhesus Monkeys Deficient in Lutein/Zeaxanthin and Omega-3 Fatty Acids Laurie Renner; Sawan Hurst; Trevor J. McGill; Alison R. Weiss; Tim Stout; David J. Wilson; Martha Neuringer View Presentation 4111 - A0029. Biocompatible injectable hydrogel to extend the release of intravitreal Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 144 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM drugs Thomas R. Friberg; Britta M. Rauck; Carlos A. Medina-Mendez; Yadong Wang View Presentation 4112 - A0030. Effect of Repeated Delivery of Neural Progenitors on Vision Preservation in RCS Rats Bin Lu; YuChun Tsai; Grazyna Adamus; Sergey Girman; Lin Shen; David M. Gamm; Catherine W. Morgans; Brandon Shelley; Clive Svendsen; Shaomei Wang View Presentation 4113 - A0031. Comparison of intravitreally injected ranibizumab versus aflibercept in the retina and choroid of the primate eye Sylvie Julien; Ulrich Schraermeyer View Presentation 4114 - A0032. Metabolomic profiles distinguish Age-related Macular Degeneration patients Samantha Williamson; Youngja Park; Karan Uppal; ViLinh Tran; J. Allie McGrath; Anita Agarwal; Margaret A. Pericak-Vance; Jonathan L. Haines; Dean P. Jones; Milam A. Brantley View Presentation 4115 - A0033. Metabolites that discriminate between neovascular AMD and control patients associate with different ARMS2 genotypes Megan B. Parks; Youngja Park; L. Goodwin Burgess; Kichun Lee; Paul Sternberg; Dean P. Jones; Milam A. Brantley View Presentation 4116 - A0034. The Composition of the Vitreous Proteome in Patients with Wet AMD Can Differentiate Between CNV and RAP: An Important New Diagnostic Tool Stephanie M. Ecker; Joshua C. Hines; Ann O. Igbre; Bert M. Glaser View Presentation 4117 - A0035. Metabolic pathways associated with Age-related Macular Degeneration (AMD) L. Goodwin Burgess; Youngja Park; Megan B. Parks; Kichun Lee; Paul Sternberg; Dean P. Jones; Milam A. Brantley View Presentation 4118 - A0036. Age-related macular degeneration and complement C3 in liver transplant patients Samir Khandhadia; Svetlana Hakobyan; Angela J. Cree; Andrew J. Lotery View Presentation 4119 - A0037. Ophthalmologic exam in Age Macular Degeneration-Alzheimer Disease: its interest in detection, follow-up of AMD, of Alzheimer disease, its relevance to highlight the links and correlations between AMD and AD Corinne Gonzalez View Presentation 4120 - A0038. Variants in the VEGFA gene and visual outcome after anti-VEGF treatment for neovascular age-related macular degeneration Manuel M. Hermann; Philipp S. Muether; Dzenita Smailhodzic; Anneke I. Den Hollander; Bernd Kirchhof; Sascha Fauser View Presentation 4121 - A0039. Level of vascular endothelial growth factor 165b in human aqueous humor Takayuki Baba; Guzel Bikbova; Masayasu Kitahashi; Hirotaka Yokouchi; Madoka Sakurai; Mariko Kubota-Taniai; Shuichi Yamamoto View Presentation 4122 - A0040. Plasma levels of vascular endothelial growth factor and anti-vascular endothelial growth factor before and after intravitreal injection of anti-vascular endothelial growth factor Sang Jun Park; Myung Hun Yoon; Ah Reum Chung; Hee Seung Chin View Presentation 4123 - A0041. Quercetin Protects Hydrogen Peroxide Damaged Human Retinal Pigment Epithelial (hRPE) Cells and Inhibits Vascular Endothelial Growth Factor (VEGF) Production Andrew Kumar; Piyush C. Kothary; Monte A. Del Monte View Presentation 4124 - A0042. Lutein supplementation leads to a decreased level of circulating complement factors Tos TJM Berendschot; Yuan Tian; Ian J. Murray; Maria Makridaki; Rob LP van der Veen; Aize Kijlstra View Presentation 4125 - A0043. Hyperhomocysteinemia as a risk factor of polypoidal choroidal vasculopathy Hui-Chen Cheng; Po-Kang Lin View Presentation 4126 - A0044. Influence of bevacizumab on Platelet activation profile in vitro Bianka Sobolewska; Focke Ziemssen; Cornelia Grimmel; Jadwiga Kwiatkowska; Martin S. Spitzer; Meinrad Gawaz; Tilo Biedermann; Konstantinos Stellos View Presentation 4127 - A0045. Effects of Plasma Kallikrein on the neuroretina in diabetic rats GONGXIONG WU; Edward P. Feener View Presentation 4128 - A0046. Choroidal Neovascularization Response of New Zealand White Rabbits and Dutch Belt Pigmented Animals to Sustained Simultaneous Release of both VEGF and bFGF within the Suprachoroidal Space Corinne G. Wong View Presentation 4129 - A0047. Associations of IL-10 with Choroidal Neovascularization in high myopia Yukimi Yamamoto; Dai Miyazaki; Shin-ichi Sasaki; Ken-ichiro Miyake; Shuzo Kaneda; Yoshifumi Ikeda; Atsushi Yamasaki; Yoshitsugu Inoue View Presentation 414. AMD III, RE Moderator(s): Itay Chowers (Hadassah - Hebrew University Medical Center) and Christine Curcio (Univ of Alabama at Birmingham) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 4130 - A0048. Focal Retinal Sensitivity Before and After Selective Retina Therapy for Central Serous Chorioretinopathy Ayako Yasui; Manabu Yamamoto; Takeya Kohno; tasuku yoneda; Yusaku Yoshida; Hisashi Iwami; Dirk Theisen-Kunde; Yoko Miura; Ralf Brinkmann; Kunihiko Shiraki View Presentation 4131 - A0049. Automatic Temperature Controlled Retinal Photocoagulation Facilitates Four Predictable Lesion Strengths Including Sub-threshold Lesions Stefan O. Koinzer; Carola Hesse; Alexander Baade; Kerstin Schlott; Amke Caliebe; Mark Saeger; Ralf Brinkmann; Johann Roider View Presentation 4132 - A0050. Modulation of Transgene Expression in Retinal Gene Therapy by Selective Laser Treatment Daniel Lavinsky; Thomas W. Chalberg; Yossi Mandel; Philip Huie; Roopa Dalal; Michael F. Marmor; Daniel V. Palanker View Presentation 4133 - A0051. Fluorescein angiography versus superimposed OCT-guided macular laser photocoagulation Igor Kozak; Sharif El-Emam; Lingyun Cheng; Dirk-Uwe G. Bartsch; Jay Chhablani; William Freeman; Nicola G. Ghazi; J Fernando Arevalo Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 145 sur 222 View Presentation 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 4134 - A0052. Six-month Report of Selective Retina Therapy on Central Serous Chorioretinopathy in Japanese Patients Manabu Yamamoto; Takeya Kohno; tasuku yoneda; Yusaku Yoshida; Hisashi Iwami; Ayako Yasui; Dirk Theisen-Kunde; Yoko Miura; Ralf Brinkmann; Kunihiko Shiraki View Presentation 4135 - A0053. Approach to Previously Vitrectomized Patients with Neovascular AgeRelated Macular Degeneration with Reduced Response to Anti-vascular Endothelial Growth Factor Treatment Mohammad Zubair Y. Arain; Quan V. Hoang; Jason S. Slakter; Stanley Chang View Presentation 4136 - A0054. Selective retina treatment (SRT) automatically controlled by a real-time reflectometry in a rabbit model Young Jung Roh; Eric Seifert; Theisen-Kunde Dirk ; Young Gun Park ; Seungbum Kang; Ralf Brinkmann View Presentation 4137 - A0055. Effects of repeated subthreshold micropulse laser photocoagulation in rabbit eyes Dongkyu Lee; Hyunseung Kang; Sung Jin Lee; Yong Song You; Soon Hyun Kim; Oh Woong Kwon View Presentation 4138 - A0056. Classification of Rabbit Photocoagulation Lesions in Optical Coherence Tomography and Class-related Coagulation Temperatures Carola Hesse; Stefan O. Koinzer; Alexander Baade; Kerstin Schlott; Amke Caliebe; Mark Saeger; Ralf Brinkmann; Johann Roider View Presentation 4139 - A0057. Various Laser Treatments for Retinal Capillary Hemangioma Liqin Gao; Feng Zhang View Presentation 4140 - A0058. Subthreshold diode micropulse laser photocoagulation versus low-fluence photodynamic therapy for the treatment of chronic central serous chorioretinopathy Juan Giralt; Ricardo P. Casaroli-Marano; Anniken Burés-Jelstrup; Rafael Navarro; Jose Juan Martinez-Toldos; Christian Fernandez-Martinez; MSocorro Alforja; Amanda Rey Torrente View Presentation 4141 - A0059. Early changes on SD-OCT in eyes with cystoid macular edema (CME) after 577 nm subthreshold MicroPulse Laser Treatment (MPLT) Paola Salvetti; Laura de Polo; Marta Oldani; Rosita Ruello View Presentation 4142 - A0060. Threshold and Subthreshold Retinal Laser Therapy. But which Threshold? Giorgio Dorin View Presentation 4143 - A0061. Persistence of Weekly Vision Self-monitoring Behavior in NonNeovascular Age-Related Macular Degeneration Subjects Randomized to the Vision and Memory Stimulating (VMS) booklet Mark C. Roser; Patricia Beaton; Sheryl Torr-Brown; Antonia Nwanko; Gislin Dagnelie; Ava K. Bittner View Presentation 4144 - A0062. Screening for AMD at an University Hospital: Database análisis and considerations Carmen N. Demetrio; Marcelo Zas View Presentation 4145 - A0063. Zinc supplementation lowers complement overactivation in patients with age-related macular degeneration B. Jeroen Klevering; Dzenita Smailhodzic; Anneke I. Den Hollander; Johannes P. van de Ven; Joannes M. Groenewoud; Sacha Fauser; Mohamed R. Daha; Gert Jan van der Wilt; Carel B. Hoyng View Presentation 4146 - A0064. Novel Laser treatment for Early Age-related Macular Degeneration Kate Brassington; Lyle Gurrin; Khin Zaw Aung; Robyn H. Guymer View Presentation 4147 - A0065. ex vivo Spectral Domain Optical Coherence Tomography (SD-OCT) of Retina-Choriocapillaris (R-CC) Specimen: Factors influencing Image Quality Laurenz L. Sonnentag; Salvatore Grisanti; Martin Rudolf View Presentation 4148 - A0066. Quantitative Optical Coherence Tomography Analysis Of Change in Pigment Epithelial Detachment Morphology Following Intravitreal Aflibercept Injection In Eyes With Recalcitrant Neovascular Age-Related Macular Degeneration Mihai Mititelu; Dilraj S. Grewal; Daniel Sarezky; Rukhsana Mirza; Manjot K. Gill; Alice T. Lyon View Presentation 4149 - A0067. Drusen Detection on Multimodal Imaging- Early Markers Observational Study Rufino Silva; Ruth E. Hogg; George Murphy; Giovanni Staurenghi; Chiara Rosina ; Ana Rita Santos; Usha Chakravarthy View Presentation 4150 - A0068. Automated prediction of AMD progression from quantified SD-OCT images Theodore Leng; Luis de Sisternes; Qiang Chen; Jeffrey Ma; Vibha Mahendra; Daniel Rubin View Presentation 4151 - A0069. Significance of Drusen Regression in Intermediate Age-Related Macular Degeneration (AMD) in Progression to Advanced Disease Tanya Glaser; E Lauren Doss; Elvira Agrón; Divya L. Nigam; Emily Y. Chew; Wai T. Wong View Presentation 4152 - A0070. The evaluation of fundus auto-fluorescence ( FAF) patterns in patient’s with Geographic Atrophy( GA) and the correlation with visual acuity Ina K. Jaurre; Shama Mudhar; Nitin Jain; Michail Polyzos; Geeta Menon; Lorraine North; Manju N. Chandran View Presentation 4153 - A0071. Investigation into the ability of Preferential Hyperacuity Perimetry (PHP) to detect reactivation of neovascularisation in patients undergoing ranibizumab injections for age-related macular degeneration (AMD) Stephanie Mroczkowska; Antonio Calcagni; Jonathan M. Gibson; Usha Chakravarthy; Ruth E. Hogg View Presentation 4154 - A0072. Automated Drusen Segmentation and Quantification from SD-OCT Images to Predict AMD Progression Luis de Sisternes; Theodore Leng; Qiang Chen; Jeffrey Ma; Vibha Mahendra; Daniel Rubin View Presentation 4155 - A0073. Factors that predict the incidence of fellow eye in age-related macular degeneration Kyung Min Koh; Young Ju Lew; Moon Jung Choi; Su Jin Yoo; Sung Won Cho; Dongwon Lee; Tae Gon Lee; Chul Goo Kim; Jung Il Han View Presentation 4156 - A0074. Development of Choroidal Neovascularization in the Second Eye of Neovascular AMD Patients Treated with Anti-VEGF Drugs Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 146 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Jonah Abraham; Michael J. Elman View Presentation 4157 - A0075. The Dynamics of Hyperreflectant Central Target Lesions In Reticular Macular Disease (RMD) In Age-related Macular Degeneration (AMD) Nicole M. Pumariega; Rachel M. Cymerman; Brendan Butler; Nathalie Massamba; Eric H. Souied; Roland Smith View Presentation 4158 - A0076. Relationship between reflectivity and volume of subretinal tissue in choroidal neovascular membranes associated with age-related macular degeneration Wissam Charafeddin; Srinivas Sadda; Muneeswar Nittala; Mark S. Humayun; Aldo A. Oregon-Miranda View Presentation 4159 - A0077. Rod and Cone function and its relationship to OCT sub structural changes in Age-related Macular degeneration Brighu Swamy; Evan N. Wong; Simona Degli Esposti; Pearse A. Keane; Michael D. Crossland; Dawn A. Sim; Adnan Tufail; Fred K. Chen View Presentation 4160 - A0078. OPERA (Optos Peripheral Retina AMD) Study Croatia: Reticular pigmentation in AMD vs. controls Vesna Jurisic Friberg; Biljana Andrijevic Derk; Tamara Knezevic; Mia Zoric-Geber; Goran Bencic; Zoran Vatavuk; Thomas R. Friberg View Presentation 4161 - A0079. Morphological characteristics associated with drusen progression on Spectral Domain OCT (SD-OCT) Jeong W. Pak; Amitha Domalpally; Dawn Myers; Xiufen Yang; Ashwini R. Narkar; Yijun Huang; Ronald P. Danis View Presentation 4162 - A0080. Clinical Outcomes of Eyes with Neovascular Lesions Composed of >50% Blood Treated with Anti-VEGF Therapy in the Comparison of AMD Treatments Trials (CATT) Michael M. Altaweel; Juan E. Grunwald; Ebenezer Daniel; Gui-Shuang Ying; Jiayan Huang; Glenn J. Jaffe View Presentation 4163 - A0081. Dark Adaptometry As a Functional Outcome Measure in Age-Related Macular Degeneration E Lauren Doss; Tanya Glaser; Elvira Agrón; Divya L. Nigam; Wai T. Wong; Emily Y. Chew; Catherine A. Cukras View Presentation 4164 - A0082. Diagnostic accuracy of multifocal pupillographic objective perimetry in early age-related macular degeneration Faran Sabeti; Aiasha Saikal; Maria Kolic; Corinne F. Carle; Rohan W. Essex; Andrew C. James; Ted Maddess View Presentation 4165 - A0083. Imaging of Focal Hyperpigmentary Changes in Intermediate Age-related Macular Degeneration – A Longitudinal Analysis Arno P. Goebel; Sophia Grundei; Monika Fleckenstein; Frank G. Holz; Steffen SchmitzValckenberg View Presentation 4166 - A0084. Reduction of the OCT second hyper-reflective band intensity is associated with a decreased in retinal function in eyes with age-related macular degeneration Chi D. Luu; Zhichao Wu; Lauren N. Ayton; Robyn H. Guymer View Presentation 4167 - A0085. Progression of Reticular Macular Disease (RMD) in Age-Related Macular Degeneration (AMD) Rachel M. Cymerman; Nicole M. Pumariega; Adam G. Sperber; Nathalie Massamba; Eric H. Souied; Roland Smith View Presentation 4168 - A0086. Imaging of reticular drusen by multi-spectral confocal scanning laser ophthalmoscopy imaging Jasmin Anke Ilka Auge; Julia S. Steinberg; Monika Fleckenstein; Frank G. Holz; Steffen Schmitz-Valckenberg View Presentation 4169 - A0087. Reticular Pseudodrusen in Early Age-Related Macular Degeneration is Associated with Choroidal Thinning Aakriti Garg; Maris Oll; Suzanne Yzer; Rando Allikmets; Stanley Chang; Gaetano R. Barile; Roland Smith; John C. Merriam; Stephen H. Tsang; Srilaxmi Bearelly View Presentation 4170 - A0088. Reticular pseudodrusen and their topographic relation to choroidal watershed zones and localized changes in choroidal volume and choroidal thickness Florian Alten; Christoph R. Clemens; Nicole Eter View Presentation 4171 - A0089. Long-term evaluation of drusen area and volume using polarizationsensitive OCT Ferdinand G. Schlanitz; Bernhard Baumann; Matthias Bolz; Erich Gotzinger; Michael Pircher; Christoph K. Hitzenberger; Ursula Schmidt-Erfurth View Presentation 4172 - A0090. Longitudinal analysis of reticular drusen associated with age-related macular degeneration Julia S. Steinberg; Jasmin Anke Ilka Auge; Monika Fleckenstein; Frank G. Holz; Steffen Schmitz-Valckenberg View Presentation 4173 - A0091. Preferential Hyperacuity Perimetry Monitoring in Patients During Treatment of Neovascular Age-related Macular Degeneration Merina Thomas; Yulia Wolfson; Voraporn Chaikitmongkol; Neil M. Bressler View Presentation 4174 - A0092. Visual outcomes of an Inject and Extend protocol of intravitreal antivascular endothelial growth factor treatment in neovascular age-related macular degeneration over two years Farshad Abedi; Sanjeewa Wickramsinghe; Amirul Islam; Kellie M. Inglis; Robyn H. Guymer View Presentation 4175 - A0093. PROSPECTIVE RANDOMIZED CONTROLLED TRIAL OF COMBINATION RANIBIZUMAB AND KETOROLAC FOR WET AGE-RELATED MACULAR DEGENERATION Andrea Russo; Ciro Costagliola; Luisa Delcassi; Mario R. Romano; Francesco Semeraro View Presentation 4176 - A0094. Aflibercept Rescue of Bevacizumab- or Ranibizumab-Resistant Choroidal Neovascularization in Age-Related Macular Degeneration Cheryl A. Arcinue; Feiyan Ma; Giulio Barteselli; Su-Na Lee; Sharif El-Emam; Aubrey L. Doede; Maria Laura Gomez; William Freeman View Presentation 415. Retinal and Photoreceptor Degeneration II: Cell Biology View Session Details Moderator(s): Susan Brockerhoff (University of Washington) and Ulrich Luhmann (UCL Institute of Ophthalmology) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 4177 - B0170. Myo/Nog Cells Promote Photoreceptor Cell Survival in the Stressed Retina Arturo Bravo-Nuevo; alice brandli; Jacquelyn V. Gerhart; Meghan Pitts; Jonathan Stone; Mindy George-Weinstein Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 147 sur 222 View Presentation 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Withdrawn 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 4178 - B0171. Responsiveness of rhodopsin kinase GRK1 promoter activity to light Shahrokh C. Khani; Zhila Oskouie View Presentation 4179 - B0172. Early indications of pending degeneration in a mouse model of photoreceptor light damage Emily Levine; Robert J. Zawadzki; Hwai-Jong Cheng; Scott I. Simon; Edward N. Pugh; Marie E. Burns View Presentation 4180 - B0173. Constitutive Rhodopsin Activation rather than Mistrafficking Results in Photoreceptor Death in the D190N Preclinical Model of Retinitis Pigmentosa Javier Sancho-Pelluz; Winston Lee; Yiting Tsai; Iyas Washington; Stephen H. Tsang; Chyuan-Sheng Lin View Presentation 4181 - B0174. Insufficient proteasomal activity is a common stress factor in multiple forms of inherited retinal degeneration Ekaterina Lobanova; Stella Finkelstein; Nikolai P. Skiba; Vadim Y. Arshavsky View Presentation 4182 - B0175. Decreased Proteasomal Activity Causes Retinal Degeneration in Mice Ryo Ando; Kousuke Noda; Utano Tomaru; Mamoru Kamoshita; Yoko Ozawa; Shoji Notomi; Toshio Hisatomi; Atsuhiro Kanda; Susumu Ishida View Presentation 4183 - B0176. Rod Photoreceptor neuritic sprouting is responsive to Sema3A Frank Kung; Abram Axelrod; Dionicio R. Siegel; Ellen Townes-Anderson View Presentation 4184 - B0177. Strain Dependence of Myeloid Cell-Associated Retinal Dysplasia in Crb1rd8 Mice Mark P. Krebs; Wanda Hicks; Lisa Stone; Jürgen Naggert; Patsy M. Nishina View Presentation 4185 - B0178. The genetic background determines the severity of retinal pathology in homozygous Crb1rd8/rd8 mice Ulrich F. Luhmann; Livia S. Carvalho; Jill Cowing; Peter M. Munro; Paul Potter; James W. Bainbridge; Robin R. Ali View Presentation 4186 - B0179. Characterization of a Novel Mouse Mutant with Retinal Degeneration and Male Infertility Chun-hong Xia; Bo Chang; Xiaohua Gong View Presentation 4187 - B0180. Electroretinographic and OCT Retinal Morphologic Characterization of the CrxRdy Cat: An Animal Model for Severe Dominant Retinopathies Associated with CRX Mutations Laurence M. Occelli; Joshua T. Bartoe; Janice R. Querubin; Kristina Narfstrom; Simon M. Petersen-Jones View Presentation 4188 - B0181. Comparative analysis of neurodegenerative markers in ten different animal models for retinal degeneration reveals prevalence of non-apoptotic cell death mechanisms Blanca Arango-Gonzalez; Dragana Trifunović; Ayse Sahaboglu-Tekgöz; Katharina Kranz; Stylianos Michalakis; Pietro Farinelli; Sandra Cottet; Per A. Ekstrom; Marius Ueffing; Francois Paquet-Durand View Presentation 4189 - B0182. Mechanism of cGMP-induced Retinal Degeneration Tian Wang; Jeannie Chen; Stephen H. Tsang View Presentation 4190 - B0183. Genetic deletion of S-opsin prevents rapid cone degeneration in a mouse model of Leber congenital amaurosis Tao Zhang; Alex Jones; Shixian Wang Wang; Edward N. Pugh; Wolfgang Baehr; Yingbin Fu View Presentation 4191 - B0184. Gene Expression Alterations in Mouse Retina with Deficiency of Cone Cyclic Nucleotide-gated Channel Subunits CNGA3 and CNGB3 Hongwei Ma; Arjun Thapa; Lynsie M. Morris; Stylianos Michalakis; Martin Biel; Mark B. Frank; Melissa Bebak; Xi-Qin Ding View Presentation 4192 - B0185. Inhibition of S1P degradation rescues 661W cells from oxidative stress Carlotta Fabiani; Paola Signorelli; Anna Caretti; Riccardo Ghidoni View Presentation Include in Itinerary 4193 - B0186. Calcium fluxes in degenerating pde6cw59 mutant zebrafish cones indicate a non-apoptotic mechanism of cell death Susan E. Brockerhoff; Eva Y. Ma; Alaron Lewis; George Stearns View Presentation 4194 - B0187. Molecular mechanisms that contribute to vision loss in T17M RHO mice Sonali R. Nashine; Yogesh Bhootada; Alfred S. Lewin; Marina S. Gorbatyuk View Presentation 4195 - B0188. Extracellular ATP accelerates photoreceptor cell death via ligation of P2X7 receptor in retinal detachment Shoji Notomi; Toshio Hisatomi; Yusuke Murakami; Atsunobu Takeda; Yasuhiro Ikeda; Hiroshi Enaida; Tatsuro Ishibashi View Presentation 4196 - B0189. Identification and characterization of Tubby C-terminal binding proteins by ORF phage display Nora B. Caberoy; Gabriela S. Alvarado; Josephine N. Nocillado View Presentation 4197 - B0190. Interaction of Tubby-like protein-1 (Tulp1) and Microtubule-Associated Proteins (MAPs) in the Mouse Retina Lindsey A. Ebke; Gregory H. Grossman; Craig D. Beight; Gayle J. Pauer; Stephanie A. Hagstrom View Presentation 4198 - B0191. The Protective effects of Resveratrol in Experimental Retinal Detachment Wei Huang; Guorong Li; Jianming Qiu; Pedro Gonzalez; Pratap Challa View Presentation 4199. LED light source induced retinal photoreceptor hazard in a rat model Yu-Man Shang; Chang-Hao Yang; Gen-Hsuh Wang; Luke Long-Kuang Lin View Presentation 4200 - B0193. Neuroprotective effects of norgestrel in retinitis pigmentosa: preservation of retinal cytoarchitecture and synaptic connectivity Violeta Gomez-Vicente; Laura Fernandez-Sanchez; Gillian Groeger; Francesca Doonan; Tom G. Cotter; Nicolas Cuenca View Presentation 4201 - B0194. Manipulating MSC Homing To Enhance Its Efficacy in Preserving Vision Shaomei Wang; YuChun Tsai; Sergey Girman; Lin Shen; Catherine W. Morgans; Grazyna Adamus; Weidong Xiong; Vaithi Arumugaswami; Clive Svendsen; Bin Lu View Presentation 4202 - B0195. NecroX-5 Rescue Retinal Degeneration Induced by N-methyl-Nnitrosourea in Rats Sun-Sook Paik; Ji Hyun Jeon; In-Beom Kim View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 148 sur 222 416. Uveal Melanoma Moderator(s): Tatyana Milman (New York Eye and Ear Infirmary) and Rebecca Stacy (Massachusetts Eye and Ear Infirmary, Harvard Medical School) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 4203 - B0196. Comparison of Two Melanoma Cell Lines as Mouse-Models of Uveal Melanoma Marta M. Kilian; Karin U. Loeffler; Hans E. Grossniklaus; Frank G. Holz; Christiane Pfarrer; Christian Kurts; Martina C. Herwig View Presentation 4204 - B0197. Calcium regulation by transient receptor potential channels in human uveal melanoma cells Stefan Mergler; Arina Boehm; Raissa Derckx; Lisa Schmelzer; Fabian Garreis; Aline Riechardt View Presentation 4205 - B0198. Unusual sodium-potassium dynamics and Na,K-ATPase expression in Mel-290 uveal melanoma cells Elena B. Rodriguez de Turco; Nicholas A. Delamere; Mohammad Shahidullah View Presentation 4206 - B0199. Host Pigment Epithelium-Derived Factor (PEDF) Prevents Progression of Uveal Melanoma Metastasis in the Liver and Inhibits Formation of Blood Vessels in the Metastatic Microenvironment John M. Lattier; Hua Yang; Susan Crawford; Hans E. Grossniklaus View Presentation 4207 - B0200. Pre-clinical analysis of Crizotinib in MAPK independent uveal melanoma metastases Pieter van der Velden; Mark de Lange; Mieke Versluis; Gregorius P. Luyten; Martine M. Jager View Presentation 4208 - B0201. Vemurafenib as a therapeutic option for treatment of melanoma Simon F. Leicht; Christian M. Wertheimer; Raffael Liegl; Anselm Kampik; Kirsten EiblLindner View Presentation 4209 - B0202. 5-Azacytidine Reduces Growth, Invasiveness, and Clonogenicity of Uveal Melanoma Cells and Decreases the Rate of Metastasis Fatemeh Rajaii; Laura Asnaghi; Shannath L. Merbs; James T. Handa; Charles Eberhart View Presentation 4210 - B0203. Cytotoxic Effects of the Combination of Resveratrol and N-acetylcysteine on Cultured Human Uveal Melanoma Cells Tommaso Vagaggini; Dan-Ning Hu; Anthony Sclafani; Steven A. McCormick; Joan E. Roberts View Presentation 4211 - B0204. Simultaneous Inhibition of the HGF/MET and Erk1/2 Pathways Affect Uveal Melanoma Cell Growth and Migration Chandrani Chattopadhyay; Elizabeth A. Grimm; Scott E. Woodman View Presentation 4212 - B0205. Cyclooxygenase-2 (COX-2) expression in primary uveal melanoma and the potential role for adjuvant treatment with COX-2 inhibitors Lindsay E. Adam; James B. Massengill; Colleen M. Cebulla; Mohamed H. AbdelRahman View Presentation 4213 - B0206. Antimicrobial Peptide Expression and Potential Roles in Uveal Melanoma Pathogenesis Joseph C. Manarang; Deborah C. Otteson; Adrian Glasser; Alan R. Burns; Alison M. McDermott View Presentation 4214 - B0207. Improved Specimen Handling for Optimizing Diagnostic Yield from Fine Needle Aspiration Biopsy of Uveal Tumors Nieraj Jain; Victor M. Elner; Hakan Demirci View Presentation 4215 - B0208. Heterogeneity of Monosomy 3 in Fine Needle Aspiration Biopsy of Choroidal Melanoma Melinda Chang; Nagesh Rao; Lariza Johnson; Tara McCannel View Presentation 4216 - B0209. Prognostic FNAB of Uveal Melanoma Arun D. Singh; Mary E. Aronow; Charles V. Biscotti; Raymond Tubbs; Lynn Schoenfield; Pierre Triozzi View Presentation 4217 - B0210. Extraocular Extension of Uveal Melanoma After Fine Needle Aspiration, Vitrectomy, or Open Biopsy Amy C. Schefler; Daniel Gologorsky; Brian Marr; Carol L. Shields; Ignacio Zeolite; David H. Abramson View Presentation 4218 - B0211. A comparison of gene expression profiling versus multiplex ligationdependent probe amplification in metastatic risk prediction in choroidal melanoma Sarah E. Coupland; Bertil E. Damato; Helen Kalirai; Marcela Baudo; Chris Bergstrom; Jill R. Wells; Tero Kivela; Hans E. Grossniklaus View Presentation 4219 - B0212. Prognostic implications of GEP class 2 in clinical practice: a single center experience with 273 cases James J. Augsburger; Zelia M. Correa View Presentation 4220 - B0213. Choroidal Melanoma pronostication: a robust and costless classifying system Nathalie Cassoux; Laurence Desjardins; Corine Plancher; Bernard Asselain; Christine Levy-Gabrielle; Livia Lumbroso-Le Rouic; Manuel J. Rodrigues; Xavier Sastre; Sophie Piperno-Neumann; Jerome Couturier View Presentation 4221 - B0214. Relationship between rate of choroidal melanoma flattening following plaque radiotherapy and GEP class of tumor cells Zelia M. Correa; James J. Augsburger View Presentation 4222 - B0215. The role of Osteopontin expression in the mechanism of invasion and metastasis potential in Uveal Melanoma Bin Li View Presentation 4223 - B0216. BAP1 mutations in uveal melanoma Anna E. Koopmans; Robert M. Verdijk; Thierry van den Bosch; Mike M. van den Berg; Jolanda Vaarwater; Dion Paridaens; Emine Kilic; Annelies de Klein View Presentation 4224 - B0217. Gender differences and estrogen and progesterone receptor expression in uveal melanoma Lynn Schoenfield; Thomas Plesec; Erinn Downs-Kelly; Mary Beth Aronow; Paula Carver; Raymond Tubbs; Arun D. Singh View Presentation 4225 - B0218. Detection of circulating tumor cells in uveal melanoma using the CellSearch® system Martina Angi; Leila Khoja; Bertil E. Damato; Paul Lorigan; Caroline Dive; Sarah E. Coupland; Helen Kalirai View Presentation 4226 - B0219. Quantification of circulating tumour cells in patients with choroidal Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 149 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM melanocytic tumours: correlation with clinical risk factors Manuel F. Bande; Maria Santiago; Purificacion Mera; Maria Jose Blanco; Laura MuineloRomay; Carmela Capeans; Maria Pardo; Antonio Piñeiro View Presentation 4227 - B0220. Systemic Surveillance for Metastases in patients with Uveal Melanoma Maria M. Choudhary; Akshay Gupta; James Bena; Arun D. Singh View Presentation 4228 - B0221. Detecting hepatic metastases from ocular melanoma using MRI with a novel designed contrast agent Hua Yang; Hans E. Grossniklaus; Qing Zhang; Shenghui Xue; Fan Pu; Jingjuan Qiao; Zhi-Ren Liu; Robert C. Long; Jenny Yang View Presentation 4229 - B0222. In vivo contrast-enhanced high-frequency ultrasonography of experimental uveal melanoma: imaging features and histopathologic correlations Hans E. Grossniklaus; Shin J. Kang; Qing Zhang View Presentation 4230 - B0223. Enhanced Depth Imaging Optical Coherence Tomography of Choroidal Melanoma Before and After Plaque Radiation Therapy Denise S. Kim; Hakan Demirci View Presentation 4231 - B0224. Enhanced Depth Imaging Optical Coherence Tomography of Tumors of the Retina and Choroid: Comparison to B-scan ultrasonography Euiyong Kweon; Jaysun G. Frisch; Peter G. Hovland View Presentation 4232 - B0225. EDI-OCT Findings in Unilateral Choroidal Melanocytosis with Macular Involvement Sruthi Arepalli; Marco Pellegrini; Carol L. Shields View Presentation 4233 - B0226. Macular Choroidal Thickness in Uveal Melanoma Patients treated with Plaque Radiotherapy Ira H. Schachar; Hakan Demirci View Presentation 4234 - B0227. Radiation Therapy for Small Choroidal Melanoma: 10-years Experience with Palladium-103 Plaque Radiation Therapy Kimberly J. Chin; Ekaterina Semenova; Paul T. Finger View Presentation 4235 - B0228. Plaque Radiation Therapy for Large and Extra-large Choroidal Melanoma Ekaterina Semenova; Paul T. Finger View Presentation 4236 - B0229. Proton beam radiation for the treatment of large choroidal melanoma Shideh Schoenfeld View Presentation 4237 - B0230. Outcomes of Choroidal Melanomas Treated with Eye Physics® plaques: a 20-year Review Jesse L. Berry; Savita V. Dandapani; Marta Stevanovic; Melvin Astrahan; A. L. Murphree; Jonathan W. Kim View Presentation Include in Itinerary 4238 - B0231. 103Pd versus 125I Plaque Radiation Dose to Normal Ocular Structures in the Treatment of 319 Uveal Melanomas Di Zhou; Ekaterina Semenova; Ping Wong; Nina Kalach; Walter Choi; Paul T. Finger View Presentation 4239 - B0232. High Dose Rate Interstitial Radiation Therapy for Orbital Melanoma Paul T. Finger; Lawrence B. Tena; Paul Aridgides; Ekaterina Semenova; Walter Choi View Presentation 4240 - B0233. Intravitreal Bevacizumab Therapy In the Management of Radiation Maculopathy Andrew W. Stacey; Hakan Demirci View Presentation 4241 - B0234. Autocrine impact of VEGF ligands in uveal melanoma cells Konrad R. Koch; Deniz Hos; Birgit Regenfuss; Felix Bock; Jacobus J. Bosch; Claus Cursiefen; Ludwig M. Heindl View Presentation 4242 - B0235. Symptomatic Macular Melanocytic Lesions Treated with Intravitreal Bevacizumab Jella A. An; Christine Corriveau; Mikael Sebag; Sonia A. Callejo View Presentation 4243 - B0236. Minimally invasive therapy of exudative retinal detachment (ERD) due to choroidal or ciliary body melanoma after irradiation therapy compared to endoresection Ira Seibel; Dino Cordini; Gregor Willerding-Beaucamp; Jens Heufelder; Antonia M. Joussen View Presentation 4244 - B0237. Detection of Extrascleral Extension in Uveal Melanoma Christopher Burris; Vasilios Papastefanou; Caroline Thaung; Mandeep S. Sagoo; Victoria Cohen View Presentation 4245 - B0238. Extraocular extension in uveal melanoma Jackelien van Beek; Anna E. Koopmans; Jolanda Vaarwater; Annelies de Klein; Robert M. Verdijk; Emine Kilic View Presentation 4246 - B0239. Ciliary Body and Choroidal Pseudomelanoma from Hypermature Cataract in 20 Cases Marco Pellegrini; Carol L. Shields; Brad E. Kligman; Carlos G. Bianciotto; Jerry Shields View Presentation 4247 - B0240. Prevalence of Asteroid Hyalosis in Human and Canine Melanoma Eyes Heather Potter; Mozhgan Rezaei Kanavi; Amir Azari; Richard R. Dubielzig; Daniel M. Albert View Presentation 4248 - B0241. Pain as presenting feature of uveal melanoma Pukhraj Rishi; Carol L. Shields; Kaitlin A. Patrick; Mohammed A. Khan; Jerry Shields View Presentation 4249 - B0242. Analysis of the quality of life of patients receiving conservative treatment for uveal melanoma Federica Genovesi-Ebert; Clara Meo; Franco Perrone; Clara Meo; Federica Cresti; Patrizia Ferrazza; Stanislao Rizzo View Presentation Include in Itinerary 417. Accommodation and Presbyopia Correction Moderator(s): Abhiram Vilupuru (AcuFocus, Inc) and Fabrice Manns (Bascom Palmer Eye Inst, Univ of Miami) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 4250 - B0287. The Influence of Multifocal Lenses on Fine Motor Tasks Rupal Lovell-Patel; Matthew A. Timmis; Shahina Pardhan; Paul McCarthy View Presentation 4251 - B0288. Accommodative Lag, Facility and Phoria with Multifocal Contact Lenses Jiyoon Chung; Ravi C. Bakaraju; Cathleen Fedtke; Jerome Ozkan; Klaus Ehrmann; Darrin Falk; Arthur Ho; Brien A. Holden View Presentation 4252 - B0289. The role of eye dominance on through-focus visual performance in Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 150 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM modified monovision presbyopic corrections Len Zheleznyak; Aixa Alarcon; Kevin C. Dieter; Duje Tadin; Geunyoung Yoon View Presentation 4253 - B0290. Customizing depth of focus outcomes in Hyperopic Lasik using an Adaptive Optics Vision Analyzer Guillermo M. Perez; Eloy A. Villegas; Benjamin Leray; Francois J. Malecaze; Pablo Artal View Presentation 4254 - B0291. Effect of Age on Amplitude of Accommodation in Bolivia Magnus Andersson; Baskar Theagarayan View Presentation 4255 - B0292. Influences of cycloplegia with topical cyclopentolate on higher-order aberrations in myopic children Takahiro Hiraoka; Kazunori Miyata; Fumiki Okamoto; Tetsuro Oshika View Presentation 4256 - B0293. Five-year Incidence of Loss of Accommodative Ability in the Beaver Dam Offspring Study Dayna S. Dalton; Karen J. Cruickshanks; Mary E. Fischer; Barbara E. Klein; Ronald Klein; Aaron A. Pinto View Presentation 4257 - B0294. Effect of Unclean Display on Accommodative Response Masakazu Hirota; Hiroshi Uozato; Shinji Arai; Yuko Shibata View Presentation 4258 - B0295. The effect of near addition lenses on the accuracy of the accommodative response in myopic children during reading Jinhua Bao; Zhili Zheng; Hao Chen View Presentation 4259 - B0296. Tonic Accommodation Correlates with Accommodative Amplitude-Scaled Facility Test for Symptomatic Graduate Students Chunming Liu; Chris Chase; Stefanie A. Drew; Efrain Castellanos; Amy Escobar; Eric Borsting; Lawrence R. Stark View Presentation 4260 - B0297. Larger Tonic Accommodation Correlates with Better Focus at Near for Symptomatic Graduate School Students Chris Chase; Stefanie A. Drew; Amy Escobar; Chunming Liu; Efrain Castellanos; Lawrence R. Stark; Eric Borsting View Presentation 4261 - B0298. The Dynamic Accommodative Response with the Binocular open-field autorefractor and a Movable Real Target Shinji Arai; Hiroshi Uozato; Masakazu Hirota View Presentation 4262 - B0299. Suppression in the accommodative response to short-duration changes in dioptric stimulus Alistair P. Curd; Karen M. Hampson; Edward Mallen View Presentation 4263 - B0300. Accommodation induced variations of ocular axial length and retinal thickness measured with SD-OCT Chuanqing Zhou; Shanhui Fan; Zhe Chen; Xinyu Chai View Presentation 4264 - B0301. The Effect Of Age On The Lens Ultrastructure During Accommodation As Measured Using Slit Lamp Photos And Wave Front Analysis Rebecca K. Zoltoski; Elizabeth Wyles; Jennifer S. Harthan; Jer R. Kuszak View Presentation 4265 - B0302. Do Higher Order Aberrations Affect the Magnitude of Odd-error Temporal Stimuli to Accommodation? Sangeetha Metlapally; Jianliang Tong; Humza J. Tahir; Clifton M. Schor View Presentation 4266 - B0303. Impact of pupil amplitude apodization on through-focus image quality with spherical aberration Hae Won Jung; Len Zheleznyak; Geunyoung Yoon View Presentation 4267 - B0304. Contribution of shape and gradient index to the spherical aberration of donor human lenses Judith Birkenfeld; Alberto de Castro; Susana Marcos View Presentation 4268 - B0305. Crystalline lens thickness determines transverse chromatic aberration Yun Chen; Frank Schaeffel View Presentation 4269 - B0306. Prediction of human crystalline lens power and spherical aberration using an anatomically-based discrete shell model Fabrice Manns; Arthur Ho; Jean-Marie A. Parel View Presentation 4270 - B0307. Age-related Stiffening of Human Lens Measured by In Vivo Brillouin Microscopy Sebastien Besner; Giuliano Scarcelli; Roberto Pineda; Seok H. Yun View Presentation 4271 - B0308. Effect of Temperature on Lens Power, Anterior and Posterior Surface Lens Curvatures and Force during Simulated Accommodation in Cynomolgus Monkeys Jean-Marie A. Parel; Bianca M. Maceo; Cornelis J. Rowaan; Fabrice Manns; Esdras Arrieta View Presentation 4272 - B0309. Lens Spherical Aberration Changes in Cynomolgus Monkeys during Simulated Accommodation in a Lens Stretcher Bianca M. Maceo; Fabrice Manns; Alberto de Castro; Stephen Uhlhorn; Esdras Arrieta; Susana Marcos; Jean-Marie A. Parel View Presentation 4273 - B0310. Comparison between in vivo and in vitro age-related loss of accommodation in rhesus monkeys Mark Wendt; Adrian Glasser View Presentation 4274 - B0311. Age-related loss of accommodation in rhesus monkeys is associated with an age-related increase in lens stiffness Adrian Glasser; Mark Wendt View Presentation 4275 - B0312. Dynamic wavefront measurement of accommodation and pupil area in response to electric stimulation of ciliary nerve in cats Suguru Miyagawa; Toshifumi Mihashi; Yoko Hirohara; Akira Takada; Takao Endo; Hiroyuki Kanda; Tomomitsu Miyoshi; Takashi Fujikado View Presentation 4276 - B0313. Macular function contributes to the near vision performance in the patients with monofocal intraocular lens: a functional Multifocal ERG study Xialin Liu; Yao Ni; Chang He; Li Wang; Yizhi Liu View Presentation 4277 - B0314. Changes in Add Power for Near Vision after Laser in Situ Keratomileusis for Presbyopic High Myopia Yukari Tsuneyoshi; Kazuno Negishi; Miyuki Yoshida; Megumi Saiki; Naoko Kato; Ikuko Toda; Kazuo Tsubota View Presentation 4278 - B0315. Subsurface Femto-Laser Photodisruption in the Sclera for the Creation of Presbyopic Implant Tunnels Aghapi mordovanakis; Larry Baitch Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 151 sur 222 View Presentation 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 4279 - B0316. Electro-optic lens for correction of presbyopia Guoqiang Li; Thomas F. Mauger View Presentation 4280 - B0317. Tolerance to astigmatism with a small aperture corneal inlay Abhiram S. Vilupuru; Juan Tabernero; Pablo Artal View Presentation 4281 - B0318. Distribution of Achromatizing Pupil Positions and First Purkinje Reflections in a Normal Population Silvestre Manzanera; Juan Tabernero; Antonio Benito; Abhiram S. Vilupuru; Pedro M. Prieto; Pablo Artal View Presentation 4282 - B0319. Visual Simulation of Retinal Images with Various Designs of Pinhole Contact Lenses using Ray Tracing Software Kazuno Negishi; Yasuyo Nishi; Kazuhiko Ohnuma; Kazuo Tsubota View Presentation 4283 - B0320. Visual Simulation of Retinal Images with Various Designs of Pinhole Contact Lenses Yasuyo Nishi; Kazuno Negishi; Kazuhiro Watanabe; Yuki Hidaka; Hidemasa Torii; Megumi Saiki; Kazuo Tsubota View Presentation 418. Antibiotics and Corneal Disease Moderator(s): Haydee Bazan (LSU Health Sciences Center) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Withdrawn 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 4284 - C0022. The use of predatory prokaryotes to control human ocular pathogens Robert M. Shanks; Kevin To; Nicholas A. Stella; Kimberly M. Brothers; Regis P. Kowalski; Eric G. Romanowski; Daniel E. Kadouri View Presentation 4285 - C0023. Susceptibility of Stenotrophomonasmaltophilia to Antibiotics and Contact Lens Multipurpose Solutions Keizo Watanabe; Hua Zhu; Rani Bandara; Shiro Higaki; Masahiko Fukuda; Yoshikazu Shimomura; Mark D. Willcox; Brien A. Holden View Presentation 4286 - C0024. A Comparison of Prophylactic Antibacterial Efficacy of Besifloxacin 0.6% versus Moxifloacin 0.5% at 1 hour and 3 days Prior to Phacoemulsification Frank A. Bucci View Presentation 4287 - C0025. Cytotoxicities of various ophthalmic antimicrobial solutions in SV40immortalized human corneal epithelial cells Jae Lim Chung; Sang Wroul Song; Byung Yeop Kim; Joon H. Lee; Kyoung Yul Seo View Presentation 4288 - C0026. The In Vitro Activity of Tigecycline for Clinically Relevant Ocular Pathogens Regis P. Kowalski; Tyler Kowalski; Eric G. Romanowski; Robert M. Shanks; Leela Raju View Presentation 4289 - C0027. TEAR OSMOLARITY IN PEDIATRIC PATIENTS WITH CYSTIC FIBROSIS Livio Giulio Marco Franco; Vittorio De Grande; Santo Stella; Michele Reibaldi; Elena Lionetti; Chiara Franzonello; Salvatore Leonardi; Caterina Gagliano; Andrea Russo; Mario La Rosa View Presentation 4290 - C0028. The Pharmacokinetics and Aqueous Humor Penetration of Besifloxacin 0.6% and Moxifloxacin 0.5% in Patients Undergoing Cataract Surgery Ruth Evans; Frank A. Bucci View Presentation 4291 - C0029. Ocular Pharmacokinetics, Safety and Efficacy of Intracameral Moxifloxacin 0.5% Solution in a Rabbit Model Yonca Akova; Leyla Asena; Mustafa T. Göktas; Atilla Bozkurt; Umit Yasar; Gulten Karabay; Ebru Demiralay View Presentation 4292 - C0030. High affinity LPS-binding branched peptides display synergistic activity with other antibiotics Rajamani Lakshminarayanan; Shouping Liu; Roger W. Beuerman View Presentation 4293 - C0031. The Comparison of Topical RPX-978 (an Ophthalmic Formulation of Tigecycline) to Topical Vancomycin in a MRSA Rabbit Keratitis Model Eric G. Romanowski; Kathleen A. Yates; Katherine E. O'Connor; Francis S. Mah; Leela Raju; Robert M. Shanks; Regis P. Kowalski View Presentation 4294 - C0032. The Monthly Eye Drop: Development of a Long-term, Noninvasive Glaucoma Treatment System Morgan V. Fedorchak; Anthony Cugini; Joel S. Schuman; Steven R. Little View Presentation 4295 - C0033. Chronic alcohol consumption and corneal pathologies: the role of aldehyde dehydrogenases Naseem Ansari; Min Zhang; Cheng Wang; John Papaconstantinou; Vasilis Vasiliou; Bhupendra Kaphalia View Presentation 4296 - C0034. Small non-hydrophobic, cationic peptide with in vitro and in vivo efficacy against Gram negative bacteria Roger W. Beuerman; Shouping Liu; Rajamani Lakshminarayanan; Jianguo Li; Bai Yang View Presentation 4297 - C0035. Molecular Design of Novel Membrane Targeting Antimicrobials with Improved Membrane Selectivity Using Natural Compound as a Scaffold Shouping Liu; Hanxun Zou; Jun-Jie Koh; Jianguo Li; Rajamani Lakshminarayanan; Roger W. Beuerman View Presentation 4298 - C0036. In vitro analysis of the effect of steroid in combination with antimicrobial on co-cultures of bacteria and fungi isolated from keratitis Herlinda Mejia-Lopez; Lucero Y. Martínez-López; Alejandro Clinent-Flores; Aida V. Rodríguez-Tovar; Luis A. Bautista-Hernández; Victo M. Bautista de Lucio; María A. Martínez-Rivera View Presentation 4299 - C0037. Iontophoresis transcorneal delivery technique for transepithelial corneal collagen crosslinking with riboflavin in a rabbit model Vincent J. Soler; Myriam Cassagne; Camille Laurent; Anne Galinier; Pierre R. Fournie; Stéphane Galiacy; Pierre Roy; Francois J. Malecaze View Presentation 4300 - C0038. Comparative Analysis of In Vitro Biocompatibility Assays of Polyhexamethylene Biguanide Disinfecting Contact Lens Multi-Purpose Solutions Mercedes Salvador-Silva; Ling C. Huang; James Cook View Presentation 4301 - C0039. Benzalkonium Chloride Stimulation of THP-1 Differentiated Macrophages in Vitro Sylvain Michee; Francoise Brignole-Baudouin; Luisa Riancho; William H. Rostene; Christophe Baudouin; Antoine Labbe View Presentation 4302. Delayed corneal wound healing resulting from the administration of Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 152 sur 222 Withdrawn 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM fluoroquinolone antibacterial ophthalmic solutions and its causes Masamichi Fukuda; Yusuke Seki; Yusuke Kurihara; Shino Enta; Naoko Shibata; Kenta Hagiwara; Hiromi Osada; Sinsuke Shibata; Eri Kubo; Hiroshi Sasaki View Presentation 4303 - C0041. Penetration of Eye Drop Solutions of Fluoroquinolones into the Cornea and Anterior Chamber of Human Enucleated Eyes Sidney J. Sousa; Gleilton C. Mendonça View Presentation 4304 - C0042. To evaluate the efficacy of corneal collagen crosslinking in fungal corneal ulcers shah nawaz; Prafulla K. Maharana; Namrata Sharma; Rasik B. Vajpayee View Presentation 4305 - C0043. Improvement of post-cataract dry eye by 0.05% cyanocobalamine plus 0.5% taurine and 0.5% long-chained hyaluronic acid Federico Solignani; Monica Zurria; Maurizio Rolando View Presentation 4306 - C0044. Title: Susceptibility Profiles in Infectious Keratitis as an Aid in Antibiotic Selection Mark L. Hill; Duncan A. Friedman; Elizabeth Cooper; John Parker View Presentation 4307 - C0045. Photodynamic antimicrobial chemotherapy for methicillin-resistant Staphylococcus aureus -in vitro, biofilm, and ex vivo bovine keratitis model Hsiao-sang Chu; Fung-Rong Hu; Chin-Tin Chen View Presentation 419. Dry Eye and Lacrimal Gland IV Moderator(s): Benjamin Sullivan (TearLab Corp) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 4308 - C0046. Tear specific potential protein biomarker identification by 2D-DIGE based proteomics in Dry eye syndrome associated with Rheumatoid Arthritis Narayanasamy Angayarkanni; Saijyothi Venkata Aluru; Utpal Tatu; Shweta Agarwal; Bhaskar Srinivasan; Geetha Krishnan Iyer; Sivakumar M. Rajappa; Umashankar Vetrivel; Prema Padmanabhan View Presentation 4317 - C0055. Impact of azithromycin on lipid accumulation in immortalized human meibomian gland epithelial cells Yang Liu; Wendy R. Kam; Juan Ding; David A. Sullivan View Presentation 4309 - C0047. The Correlation of Muc-16 as compared to Dry Eye Clinical Endpoints in Dry Eye and Normal Subjects Michael Watson; Keith J. Lane; Andy Whitlock; George W. Ousler View Presentation 4310 - C0048. The Use of Soluble Muc-16 (CA-125) as a Clinically Relevant Biomarker and Endpoint in a Mouse Model of Dry Eye Jennifer Brackett; Laura Belen; Kortni Violette; Andy Whitlock View Presentation 4311 - C0049. Megalin and Cubilin Levels are Altered in Tear-Producing Glands of Vitamin D Receptor Null Mice Xiaowen Lu; Mitchell A. Watsky View Presentation 4312 - C0050. Changes in corneal nerve morphology and epithelial wound healing after prolonged ocular dryness induced by lacrimal gland ablation Kamila Mizerska; Nicolas Cuenca; Carolina Luna; Susana Quirce; Laura FernandezSanchez; Illes Kovacs; M Carmen Acosta; Carlos Belmonte; Juana Gallar View Presentation 4313 - C0051. Isolation and characterization of progenitor cells from intact rabbit lacrimal gland Hong He; Guoying Sun; Hui Lin; Marie A. Shatos; Darlene A. Dartt; Samuel C. Yiu View Presentation 4314 - C0052. Alterations of Tear Functions and Ocular Surface Epithelial Differentiation in the SOD-1 Knock- out Mouse MURAT DOGRU; Takashi Kojima; Taeko Nagata; Ayako Igarashi; Kazunari Higa; Yoshiyuki Satake; Seika Shimazaki; Shimizu Takahiko; Kazuo Tsubota; Jun Shimazaki View Presentation 4315 - C0053. L-carnitine, Erythritol and Betaine Suppress the Production and Activity of Matrix Metalloproteinases in Primary Human Corneal Epithelial Cells Exposed to Hyperosmotic Stress Ruzhi Deng; Zhitao Su; Jing Lin; Xia Hua; De-Quan Li; Stephen C. Pflugfelder View Presentation 4316 - C0054. Suppressive effects of 17β-estradiol on immortalized human meibomian gland epithelial cells Wendy R. Kam; David A. Sullivan View Presentation 4318 - C0056. A Comparative Evaluation of Lipid-based Formulations for Dry-Eye Therapy using a Corneal Epithelial Cell Desiccation Model and Physicochemical Measurements Paramita Sarkar; Zora Marlowe; Amy Walsh; Brian Glass; Tammy Kleiber; Megan E. Cavet; Karen L. Harrington; Stephen Davio View Presentation 4319 - C0057. Early Clinical Development of EBI-005, a Potent Interleukin-1 (IL-1) Receptor-1 (R1) Blocker for Topical Ocular Treatment of Dry Eye Disease (DED) Michael H. Goldstein; Gregory Zarbis-Papastoitsis; Kathryn Golden; Siddhartha Chowdhury; Cameron Wheeler; Gary N. Foulks; Joseph T. Kovalchin; Jennifer Agahigian; Eric S. Furfine View Presentation 4320 - C0058. Preclinical Development of EBI-005: a Potent Interleukin-1 (IL-1) Receptor-1 (R1) Blocker for Topical Ocular Administration was Safe in GLP Toxicology Studies and Active in a Mouse Model of Dry Eye Disease (DED) Eric S. Furfine; Kathy Collins; David Escobar; Christian Li; Patricia A. Lowden; Allyson Masci; Jesse Milling; Kelly Tenneson; Gary Wolfe; Joseph T. Kovalchin View Presentation 4321 - C0059. Soft steroid topical treatment for moderate to severe dry eye: pulse vs tapered therapy Edoardo Villani; Cesare Pirondini; Francesco Viola; Roberto Ratiglia View Presentation 4322 - C0060. Comparison of Three Commercially Available Tear Substitutes Designed for Evaporative Dry Eye Treatment Charles G. Connor; Raelyn A. Ottenbreit; Laura K. Schroeder; Jeff C. Rabin; Srihari Narayanan View Presentation 4323 - C0061. Plasmacytoid Dendritic Cells are the Primary Source of IFN-α During the Immunopathogenesis of Desiccating Stress-Induced Dry Eye Disease Michael E. Stern; Chris S. Schaumburg; Jianping Gao; Annie M. Ratanapinta; Virginia L. Calder; Larry A. Wheeler; Jerry Y. Niederkorn; Stephen C. Pflugfelder; Bruce Beutler; Argyrios N. Theofilopoulos View Presentation 4324 - C0062. Analysis of Tear Inflammatory Mediators: A comparison of Microarray and Luminex In Differing Subject Groups Karen Dionne; Kelly K. Nichols; Alison M. McDermott; Rachel L. Redfern; Jason J. Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 153 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Nichols View Presentation 4325 - C0063. Tear film cytokine analyses using a novel electrochemiluminescent array technique Lakshman N. Subbaraman; Mirunalni Thangavelu; David J. McCanna; Lyndon W. Jones View Presentation 4326 - C0064. Secretory Group Two A Phospholipase (sPLA2) Inhibition Decreases Corneal Superficial Punctate Keratitis (SPK) in Dry Eye Mice Yi Wei; Pengcheng Li; Jun Zou; Seth P. Epstein; Neha Gadaria-Rathod; Penny A. Asbell View Presentation 4327 - C0065. New recombinant hyaluronic acid for eye care and ophthalmic drug delivery Birgit Lundskov Fuhlendorff; Khadija Schwach-Abdellaoui; Fanny Longin; Corinne Eenschooten View Presentation 4328 - C0066. Preliminary Studies Of Liposomal Formulation Containing An Omega-3 Fatty Acid For Dry Eye Therapy Marta Vicario de la Torre; Omar Avelino Cruz; Maria Caballo Gonzalez; Beatriz de las Heras; Jose M. Benitez-del-Castillo; Rocio Herrero-Vanrell; Irene T. Molina-Martínez View Presentation 4329 - C0067. Clinical Comparison of Lipid-based and Aqueous Lubricant Eye drops Peter A. Simmons; Cindy Carlisle; Genming Shi; Joseph G. Vehige View Presentation 4330 - C0068. Autologous Serum Eye Drop is safe and Effective for Treatment of Dry Eyes in Graft-versus-host Disease Amir Azari; Mozhgan Rezaei Kanavi; Heather Potter; Peiman Hematti View Presentation 4331 - C0069. Ocular Surface Disease Characteristics in Patients with Ocular Graftversus-Host Disease (GVHD). Hasanain Shikari; Ujwala S. Saboo; Reza Dana View Presentation 4332 - C0070. Relationships among Tear Film Stability, Tear Osmolarity, Corneal Staining History, and Dryness Symptoms Thao N. Yeh; Nina Tran; Andrew D. Graham; Harry M. Green; Meng C. Lin View Presentation 4333 - C0071. Handheld Tear Film Lipid Layer Thickness and Non Invasive Tear Break Up Time Assessment Tool Igor Petricek View Presentation 4334 - C0072. Does the Phenol Red Thread test and the Schirmer test measure the same thing? J Peter Gierow; Sara Andersson View Presentation 4335 - C0073. Limbal capillary perfusion and blood flow velocity as a potential biomarker for evaluating dry eye Jianhua Wang; Hong Jiang; Aizhu Tao; Delia DeBuc; Yilei Shao; Jianguang Zhong; Sandra Pineda View Presentation 4336 - C0074. Real World Analytical Performance of the TearLab Osmolarity System with an Enhanced Temperature Sensor Benjamin D. Sullivan; Stephen G. Zmina; Matthew G. Zmina; Michael S. Berg View Presentation 4337 - C0075. Evaluation of the Validity of the Diagnostic Criteria for Dry Eye in Japan Using Subjective Symptoms: Osaka Study Norihiko Yokoi; Miki Uchino; Yuichi Uchino; MURAT DOGRU; Motoko Kawashima; Aoi Komuro; Yukiko Sonomura; Hiroaki Kato; Kazuo Tsubota; Shigeru Kinoshita View Presentation 4338 - C0076. Progression of Ocular Findings (PROOF) Study of the Natural History of Dry Eye: Study Design and Baseline Patient Characteristics Peter J. McDonnell; Steve Pflugfelder; Rhett M. Schiffman; David R. Hardten; Michael E. Stern; Taryn Conway; David A. Hollander View Presentation 4339 - C0077. Prevalence of dry eye sub-types and severity of evaporative dry eye using objective tests Milton M. Hom; Justin T. Kwan View Presentation 4340 - C0078. Relating Improvements in Signs and Symptoms to Duration of Dry Eye Disease (DED) after Treatment with MIM-D3 Ophthalmic Solutions Karen Meerovitch; Teresa Lama; Debra A. Schaumberg View Presentation 4341 - C0079. Automated Detection and Enumeration of Corneal Superficial Punctate Keratitis John D. Rodriguez; Patrick Johnston; Keith J. Lane; George W. Ousler View Presentation 4342 - C0080. Ocular Surface Disease prevalence in Glaucoma patients in a High Referral Ophthalmology Center in Mexico City Nallely Ramos Betancourt; Jaime D. Martinez; Francisco Beltran; Jorge Ozorno-Zarate; Cristina G. Isida Llerandi; Jesus Jimenez-Roman; Felix Gil Carrasco; Manuel Ramirez; Everardo Hernandez-Quintela View Presentation 4343 - C0081. High CAE Responders Show Greater Improvement in Signs and Symptoms of Dry Eye after Treatment with MIM-D3 George W. Ousler; Karen Meerovitch View Presentation 4344 - C0082. Dietary DHA Abrogate Intrinsic Sex-Specific Differences in Lacrimal Gland Lipid Mediator Circuits during Dry Eye Kyle M. Hu; Samantha B. Wang; Erick Lu; Patrick J. Salveson; Yuan Gao; Karsten Gronert View Presentation 4345 - C0083. Analysis of Electrolyte Composition of Precorneal Tear Film in Normal Dogs and Horses and its Comparative Values in Serum and Plasma Gil Ben-Shlomo; LaTisha N. Taylor View Presentation 4346 - C0084. Decreased Tear Production in Dogs Following Phacoemulsification R D. Whitley; Hannah E. Visser; Kyle L. Tofflemire; Elizabeth M. Whitley; Rachel A. Allbaugh; Gil Ben-Shlomo View Presentation 4347 - C0085. Impact of dry eye on reading in a population based sample of the elderly: the Salisbury Eye Evaluation Suzanne W. van Landingham; Sheila K. West; Esen K. Akpek; Beatriz E. Munoz; Pradeep Y. Ramulu View Presentation 4348 - C0086. Tear film osmolarity in rosacea patients sabah judith; Mark J. Mannis; Blythe Durbin-Johnson; Siavash Azadmanesh Samimi View Presentation 4349 - C0087. The Severity of Dry Eye with Computer Usage and Serum Lipid Levels Laura A. Norris; Zane B. Martindale; Tuong-Vi V. Mai-Tran; Alice Z. Chuang; Richard W. Yee View Presentation 4350 - C0088. Royal jelly prevents lacrimal hypofunction in Rat Visual Display Terminal Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 154 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Users Model Toshihiro Imada; Shigeru Nakamura; Ryuji Hisamura; Kazuo Tsubota View Presentation 4351 - C0089. Development of a Chinese version of the Ocular Comfort Index: preliminary validation findings Cecilia Chao; Blanka Golebiowski; Daniel Y. Cui; Fiona Stapleton View Presentation 4352 - C0090. Clinical Research of Using Oculus Keratograph for Observing the Location of First Tear Film Break-up Point Dan Wu; Jiaxu Hong; JianJiang Xu View Presentation 4353 - C0091. Allgrove Syndrome: complex eye involvement and first evaluation by laser scanning confocal microscopy Angelica Dipinto; Paolo Fogagnolo; Davide Allegrini; Maurizio Digiuni; Luca Migliavacca; Chiara Olga Pierrottet; Laura Ottobelli; Olga Oneta; Luca M. Rossetti View Presentation 4354 - C0092. How Does Increasing Ocular Surface Stimulation Affect Blinking? Ziwei Wu; Carolyn G. Begley; Ping Situ; Adam J. Winkeler; Jun Zhang; Trefford L. Simpson View Presentation 4355 - C0093. Do Tear Film Thinning Rates Vary Locally? Adam J. Winkeler; Carolyn G. Begley; Richard J. Braun; Robert Welch View Presentation 4356 - C0094. Longitudinal Mixed Effect OSDI Model in a Select Dry Eye Patient Population after Acupuncture Treatment Vanessa Bowlin; Sandeep S. Samudre; Deepinder K. Dhaliwal View Presentation 4357 - C0095. The relationship of depression and anxiety with dry eye subtypes Louis Tong; Li-Yue Hong; Ryan Lee; Yang Zhao; Sharon C. Sung; Peggy P. Chiang View Presentation 4358 - C0096. The effect of tear lipid biochemistry on tear evaporation rate during contact lens wear Athira Rohit; Simon H. Brown; Mark D. Willcox; Fiona Stapleton View Presentation 4359 - C0097. Evaluation of a Modification of the Brief Pain Inventory (BODI) as a Measure of Severity of Dry Eye Disease Maxwell Pistilli; Ellen Peskin; Hilary S. Brader; Peter Dentone; Maureen G. Maguire; Penny A. Asbell View Presentation 4360 - C0098. Correlations between non-stimulated tear levels and conjunctival surface expression of inflammation-related biomarkers in normal and aqueous-deficient dry eye patients Roderick J. Fullard; John L. Bradley; Larezia D. Williams; My-Tho K. Tran; Nicole M. Guyette; Tammy P. Than; Pearl J. Shin View Presentation 4361 - C0099. Correlations of Signs and Symptoms in Subjects with Dry Eye Sunita Saigal; Patrick Johnston; Lisa Smith View Presentation 4362 - C0100. Transcultural validation of the 5-Item Dry Eye Questionnaire (DEQ-5) for Mexican population Everardo Hernandez-Quintela; Nallely Ramos Betancourt; Jaime D. Martinez; Concepcion Santacruz Valdes; Francisco Beltran; Cecilia Ramírez-Assad; Elsa M. Mora Juarez; Alejandro Babayan View Presentation 420. Neuro-Ophthalmology: Papilledema, Characterization of Rare Diseases, and Methods of Evaluation Moderator(s): Raghu Mudumbai (University of Washington Eye Institute) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 4363 - D0001. Etiologies and visual outcomes in secondary pediatric intracranial hypertension William Rhoades; Gena Heidary View Presentation 4364 - D0002. Changes of Choroidal Thickness as Measured with Spectral Domain OCT in Patients with Idiopathic Intracranial Hypertension after Lowering of Intracranial Pressure Berthold Pemp; Karl Kircher; Andreas Reitner; Ursula Schmidt-Erfurth View Presentation 4365 - D0003. Smoking associated with cerebrospinal fluid shunt in patients with idiopathic intracranial hypertension Fran L. Wu; Michael S. Lee View Presentation 4366 - D0004. Correlation of Change in Ocular Pulse Amplitude with Change in Intracranial Pressure after Lumbar Puncture Keerthana Bolisetty; Cynthia J. Roberts; Ashraf M. Mahmoud; Monica Okon; Steven E. Katz View Presentation 4367 - D0005. Changes in Intracranial Pressure (ICP) and Ocular Pulse Amplitude (OPA) in Patients with Idiopathic Intracranial Hypertension (IIH) Steven E. Katz; Ashraf M. Mahmoud; Monica Okon; Keerthana Bolisetty; Robert H. Small; Cynthia J. Roberts View Presentation 4368 - D0006. Evaluation of Inner Retinal Thicknesses in the Macula of Patients with Chronic Papilledema from Pseudotumor Cerebri Syndrome Using Frequency Domain OCT Clara L. Afonso; Ali S. Raza; Danilo B. Fernandes; Donald C. Hood; Mario L. Monteiro View Presentation 4369 - D0007. SD-OCT in monitoring intracranial pressure in patients with CSF shunts Ali Torab Parhiz; Patrick A. Sibony; Mark J. Kupersmith View Presentation 4370 - D0008. Measurement of Retinal Nerve Fiber Layer Thickness in Eyes with Optic Disc Swelling by Using Scanning Laser Polarimetry and Optical Coherence Tomography Masayuki Hata; Kazuaki Miyamoto; Akio Oishi; Nagahisa Yoshimura View Presentation 4371 - D0009. Correlation of Peripapillary Retinal Nerve Fiber Layer Thickness and Macular Thickness as Measured by Spectral Domain Optical Coherence Tomography in Patients with Severe Vision Loss in End Stage Optic Neuropathy Joseph P. Sheehan; Courtney E. Francis; Leona Ding; Raghu C. Mudumbai View Presentation 4372 - D0010. Teaching Ophthalmoscopy to Medical Students: The TOTeMS Study Philip S. Garza; Linda P. Kelly; Beau B. Bruce; Emily B. Graubart; Nancy J. Newman; Valerie Biousse View Presentation 4373 - D0011. Evaluation of localization test under simulated very low vision conditions Takao Endo; Takashi Fujikado; Hiroyuki Kanda; Takeshi Morimoto; Shigeru Kitazawa; Kohji Nishida View Presentation 4374 - D0012. Pupil Size Dynamics During the First Minutes of Dark Adaptation While Fixating on a Target Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 155 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Withdrawn 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Boris I. Gramatikov; Kristina Irsch; David L. Guyton View Presentation 4375 - D0013. Effects of Age on the Peripheral 60-4 Test Comparing Stimulus Sizes III, V, and VI Jordan Haas; Carrie K. Doyle; Chris A. Johnson; Michael Wall View Presentation 4376 - D0014. A method of assessing global motion perception in two-year old children using the optokinetic reflex Tzu-Ying Yu; Robert J. Jacobs; Nicola S. Anstice; Nabin Paudel; Jane E. Harding; Benjamin Thompson View Presentation 4377 - D0015. Comparison of Diopsys Pattern Reversal Visual Evoked Potential Responses and Grating Acuity Measurements using the Teller Acuity Card Procedure Tina K. Green; John D. Twelker; Theresa R. Kramer; Diane J. Mercer; Charis Ober; Candice C. Donaldson; Hugh Miller; Joseph M. Miller; Erin M. Harvey View Presentation 4378 - D0016. Prospective study on the contribution of MRI in the analysis of isolated mydriasis: a new kind of neurovascular conflict Fanny Tréchot; Marc Braun; Veronique Cloche; Karine Angioi View Presentation 4379 - D0017. Sweep-VEP Acuity as a Clinical Tool in the Diagnosis of Functional Visual Loss Paula Y. Sacai; Adriana Berezovsky; Daniel M. Rocha; Sung E. Watanabe; Josenilson M. Pereira; Nívea N. Cavascan; Tarciana d. Soares; Solange R. Salomao View Presentation 4380 - D0018. Visual field defects and retinal nerve fibre layer thickness measurements using optical coherence tomography in migraine patients Anna Midelfart; Haakon Anders Bjurstrøm; Stig Rune Sollie; Erik Midelfart; Sven Midelfart View Presentation 4381 - D0019. Distinctive Clinical Signs Differentiating Oculopharyngeal Muscular Dystrophy from Myasthenia Gravis Jeffrey Peterson; Michael T. Yen; Rod Foroozan View Presentation 4382 - D0020. Ocular Manifestations and Optic Nerve Changes in Patients with Amyotrophic Lateral Sclerosis (ALS) Joseph Simonett; Jonathan Chou; Nailah Siddique; Jennifer L. Armstrong; Amani A. Fawzi; Teepu Siddique; Nicholas J. Volpe View Presentation 421. Eye Care Moderator(s): Joshua Stein (University of Michigan) and Graham Trope (University Toronto) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details 4383 - D0021. Screening of Potentially Blinding Eye Diseases by Vision Technicians at Rural Vision Centres in Southern India and their Referral Agreement with an Ophthalmologist Uday Addepalli; Suram Vasantha; Rohit C. Khanna; Krishnaiah Sannapaneni; Vilas Kovai View Presentation 4384 - D0022. Geographic Variability In The Age Of First Cataract Surgery And Rate Of Cataract Surgery Among Persons Living In Communities Throughout The U.S. Courtney Y. Kauh; Taylor S. Blachley; Paul R. Lichter; Paul P. Lee; Joshua D. Stein View Presentation 4385 - D0023. Power & type II errors in recently published ophthalmology research Zainab Khan; C. Jordan Milko; Ayaz K. Kurji; Munir Iqbal; David Almeida View Presentation 4386 - D0024. A Longitudinal Analysis of 1,660 Recipients of Bilateral Laser Peripheral Iridotomies to Determine Subsequent Need for Cataract Surgery and Additional Interventions for Glaucoma Sharmini Balakrishnan; Taylor S. Blachley; Jennifer Weizer; Paul P. Lee; Joshua D. Stein View Presentation 4387 - D0025. Are Chronic Users of Chloroquine or Hydroxychloroquine Undergoing Regular Visits to Eye Providers and Diagnostic Testing to Check for Maculopathy? Melisa Nika; Taylor S. Blachley; Paul A. Edwards; Paul P. Lee; Joshua D. Stein View Presentation 4388 - D0026. Optimizing cost-effectiveness analyses of treatments for neovascular agerelated macular degeneration using real-life data Robert P. Finger; Arthur Hsueh; Jill E. Keeffe; Robyn H. Guymer View Presentation 4389 - D0027. Comparison of Resource Consumption in Penetrating versus Endothelial Keratoplasty from 2009-2010 Duna Raoof-Daneshvar; Roni M. Shtein; Taylor S. Blachley; Maria A. Woodward; Shahzad I. Mian; Alan Sugar; Joshua D. Stein View Presentation 4390 - D0028. The Sight Loss and Vision Priority Setting Partnership (SLV-PSP) – initial survey methods, respondents’ demographics and preliminary categorisation framework Michael Bowen; Michele Acton; Dolores M. Conroy; Richard P. Wormald; Anita Lightstone; Katherine Cowan; Catey Bunce; Mark Fenton; Karen Bonstein View Presentation 4391 - D0029. Applying Lean Principles to Clinical and Translational Research in Ophthalmology Vesper Williams; Phyllis Summerfelt; Tracy Kaczanowski; Krissa Packard; Diane M. Bishop; Mara Goldberg; Alfredo Dubra; Joseph Carroll; Aneesh Suneja View Presentation 4392 - D0030. Evaluation of Fundamental Ophthalmology Knowledge among Internal Medicine and Emergency Department Residents Priya Janardhana; Manishi A. Desai View Presentation 4393 - D0031. The Ophthalmology Job Market In the Aftermath of the Great Recession Chukwuemeka C. Nwanze; Ron A. Adelman; Janine Barth View Presentation 4394 - D0032. PROSE treatment for moderate to severe ocular graft-versus-host disease: Analysis of utilization rates versus projected demand across four centers Ryan Ridges; Beth Beard; Deborah S. Jacobs View Presentation 4395 - D0033. Ophthalmology Consultation on Asymptomatic Patients Ryan K. Wong; John Huang View Presentation 4396 - D0034. The economic impact of cataract surgery in a remote Ghanaian village three years after surgical intervention John D. Welling; Emily R. Newick; Geoffrey C. Tabin View Presentation 4397 - D0035. Immediately Sequential Bilateral Cataract Surgery-A Cost-effective Procedure Monali Malvankar; William G. Hodge; Richard Filek; Munir Iqbal; Muhammad A. Shakir; Madhukar Malvankar; Swati Chavda; Francie F. Si View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 156 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 4398 - D0036. iPhone applications in ophthalmology: Current capabilities, limitations and future directions Nicholas M. Cheng; Rahul Chakrabarti; Jonathan K. Kam View Presentation 4399 - D0037. Activity and epidemiology of a recently opened ophthalmic emergency center in a University Hospital Francois Ameloot; Nelly Agrinier; Fanny Tréchot; Toufic Maalouf; Karine Angioi View Presentation 4400 - D0038. Stability of the Relationship Between Self-Reported Vision Impairment and Blindness and Medical Care Expenditures Over Time Kevin D. Frick; Elizabeth Wehler View Presentation 4401 - D0039. Glaucoma Treatment: A Closer Look at Non-adherence Sumir Pandit; Teresa C. Chen View Presentation 4402 - D0040. Predictive Factors for Incomplete Adherence to Glaucoma Management amongst Singaporean Chinese Reuben C. Foo; Hiok Hong Chan; Ecosse L. Lamoureux; Ryan Wong; Sue Wei Ho; Gwyneth Rees; Tin Aung; Shamira Perera; Tina Wong View Presentation 4403 - D0041. Patient Adherence and Persistence with Topical Ocular Hypotensive Therapy: a Claims-Based Comparison of Bimatoprost 0.01% and Travoprost with sofZia Joanna Campbell; Gail F. Schwartz; Britni LaBounty; Jonathan W. Kowalski; Vaishali D. Patel View Presentation 4404 - D0042. Identifying requirements for effective glaucoma electronic health records: a consensus study John E. Somner; Rupert R. Bourne; Peter Shah; Rob Froud View Presentation 4405 - D0043. Quality of Referral Letters to a Tertiary Glaucoma Unit and adherence to Glaucoma Guidelines Jason Cheng; Laura Beltran-Agullo; Graham E. Trope; Yvonne M. Buys View Presentation 4406 - D0044. The Utility of a Medical Student Run Glaucoma Screening Program Mona A. Kaleem; Valerie C. Lerebours; John W. Logan ; Juliana Llano; Leslie S. Jones View Presentation 4407 - D0045. Opportunistic Glaucoma Screening in Rural India: Role of Vision Centers Mona Khurana; MOHIDEEN A. KADER; Rengappa Ramakrishnan View Presentation 4408 - D0046. Qualitative Analysis of Web-Based LASIK Information Sessions Roni M. Shtein; Paul P. Lee View Presentation 4409 - D0047. Results of the Appalachian Vision Outreach Program: Year 2 J V. Odom; Rebecca Coakley; Judie Charlton; Serena Morrison View Presentation 4410 - D0048. Are outcomes in primary retinal detachment repair related to distance away from an academic medical center? Kristen Harris Nwanyanwu; Leslie M. Niziol; David C. Musch; David N. Zacks View Presentation 4411 - D0049. Consent For Future Corneal Transplantation And Eye Research From AMD Patients In An Ophthalmic Clinic Meidong Zhu; Jamie Chew; Pierre Georges; Con Petsoglou; Andrew A. Chang View Presentation 4412 - D0050. Objective and subjective severity of affections observed at emergency room in ophthalmology Aurelie Pison; Chadi Mehanna; Georges Sawiress; Reda Mikou; Astrid Queant; Antoine P. Brezin; Jean-Louis Bourges View Presentation 4413 - D0051. Acceptance, Attitudes and Beliefs Of Singaporean Chinese Towards Subconjunctival, Intracameral and Punctal Plug Methods of Sustained Glaucoma Drug Delivery Systems Hiok Hong Chan; Tina Wong; Ecosse L. Lamoureux; Shamira Perera View Presentation 4414 - D0052. Electronic Health Record Systems in Ophthalmology: Impact on Operating Room Time Requirements for Cataract Surgery Daniel C. Tu; David S. Sanders; Sarah Read-Brown; Anna S. Brown; Dongseok Choi; Thomas R. Yackel; Michael F. Chiang View Presentation 4415 - D0053. Efficiency improvements using an ophthalmological Picture Archiving and Communication System (PACS) in the diagnostic workflow of an eye hospital Karsten U. Kortuem; Wolfgang J. Mayer; Simon F. Leicht; Lukas Reznicek; Anselm Kampik; Marcus Kernt View Presentation 4416 - D0054. Ambulatory Surgery Center (ASC) Utilization by three Ophthalmic Subspecialists: 1999-2011 Kamyar Vaziri; Andrew A. Moshfeghi; Tina Hernandez-Boussard; Natalia Fijalkowski; Darius M. Moshfeghi View Presentation 4417 - D0055. Comparison of theoretical demand for glaucoma eye care by the AfricanAmerican population of cook county to the supply of ophthalmologic manpower as a pilot study of access to care Stephen Watson; Dmitry Pyatetsky View Presentation 4418 - D0056. Trends in Utilization of Ancillary Testing for Patients with Exudative Macular Degeneration and Macular Edema from 2001 to 2009 Eric W. Schneider; Prithvi Mruthyunjaya; Nidhi Talwar; Kristen Harris Nwanyanwu; Bin Nan; Joshua D. Stein View Presentation 4419 - D0057. Comparing Patient and Public Preferences for Health States Associated with Age-Related Macular Degeneration Thomas Butt; Hannah M. Dunbar; Steve Morris; Shepley Orr; Gary S. Rubin View Presentation 4420 - D0058. Provision of Mass Drug Administration for Trachoma Control: Cost per gain in coverage Sheila K. West; Harran A. Mkocha; Beatriz E. Munoz; Kevin D. Frick View Presentation 4421 - D0059. Trachoma Control: A Potential Field Test for Ocular C. Trachomatis Infection Alexander Jenson; Laura Dize; Harran A. Mkocha; Beatriz E. Munoz; Jennifer S. Lee; Sheila K. West View Presentation 4422 - D0060. Compliance with Eye Screening Guidelines among Newly-Diagnosed Diabetic Patients without Diabetic Retinopathy David J. Lee; Potyra Rosa; William J. Feuer; Byron L. Lam; Joyce C. Schiffman; Naresh Kumar; Alexis Morante View Presentation 4423 - D0061. Methods of Assessing Provider Performance for Quality Improvement Paul P. Lee; Gerald McGwin; Sanjay Asrani; William Rafferty; David Lobach; Kathy Kimrey View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 157 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 4424 - D0062. Electronic health record (EHR) systems in ophthalmology: Impact on clinical documentation David S. Sanders; Daniel Lattin; Daniel C. Tu; Sarah Read-Brown; David J. Wilson; Thomas S. Hwang; John C. Morrison; Thomas R. Yackel; Michael F. Chiang View Presentation 4425 - D0063. Ophthalmologists’ Attitudes on Implementing an Electronic Health Record System Monica M. Michelotti; Jennifer Weizer; Taylor S. Blachley; Kai Zheng; Mick Couper; Grant Greenberg; Sharon Kileny; Greta Branford; David A. Hanauer View Presentation 4426 - D0064. Implementation of electronic health record systems in ophthalmology: impact on clinical volume compared to other medical fields Travis Redd; Sarah Read-Brown; Anne Kitzmiller; Thomas R. Yackel; Dongseok Choi; Michael F. Chiang View Presentation 4427 - D0065. Physician and patient perceptions of electronic health record (EHR) use in a tertiary care ophthalmologic clinic Patrick Chan; Rishi Singh; Suzanne Charvat View Presentation 4428 - D0066. Critical Review of High Quality Ophthalmology Educational Web Resources Targeting Trainees Milad Modabber; Sourabh Arora; Karim F. Damji; Feisal Adatia View Presentation 422. Ocular Trauma Moderator(s): Gerald McGwin (Univ of Alabama at Birmingham) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 4429 - D0114. Characteristics of eyelid laceration due to dog bite in children MOHAMMAD ALI SADIQ; Iason Mantagos View Presentation 4430 - D0115. Demographic and Clinical Profile of Ocular Chemical Injuries in Children Pooja Bandivadekar; Himanshu Shekhar; Namrata Sharma; Rasik B. Vajpayee View Presentation 4431 - D0116. Motor Vehicle Crash-Associated Eye Injuries Presenting to United States Emergency Departments Grayson W. Armstrong; Allison J. Chen; James G. Linakis; Michael J. Mello; Paul B. Greenberg View Presentation 4432 - D0117. A Ten Year Review of Open Globe Trauma in Elderly Patients at an Urban Hospital Iris Y. Sheng; Alain M. Bauza; Paul D. Langer; Marco A. Zarbin; Neelakshi Bhagat View Presentation 4433 - D0118. Clinical outcomes of surgically-treated trapdoor fractures in the pediatric population Kathleen C. Oktavec; Shannath L. Merbs; Michael Grant View Presentation 4434 - D0119. Severe Ocular Trauma In The Emergency Room Albert Lin; Cassie Confait; Suzanne T. Hoadley; Madiha Ahmad; Ching J. Chen View Presentation 4435 - D0120. Outcomes and characteristics of open-globe injuries with delayed presentation Danielle Trief; Michael T. Andreoli; Ankoor S. Shah; Yoshihiro Yonekawa; Christopher M. Andreoli View Presentation 4436 - D0121. Correlation of Ocular Trauma Score and visual acuity outcomes in combat-related traumatic cataracts Michael P. Smith; Marcus Colyer; David L. Greenburg View Presentation 4437 - D0122. Ocular and adnexal injuries in patients with all-terrain vehicle accidents in West Virginia Evan Newbolt; Charles B. Chen; John Nguyen; Jennifer Sivak-Callcott; Brian D. Ellis; Chad M. Bingham View Presentation 4438 - D0123. Characteristics and Management of Traumatic Eyes with Full Thickness Corneal Lacerations Yi C. Lai; Alain M. Bauza; Paul D. Langer; Suqin Guo; David S. Chu; Albert S. Khouri; Robert D. Fechtner; Roger E. Turbin; Neelakshi Bhagat View Presentation 4439 - D0124. Nail Gun-Induced Open Globe Injuries: A Ten-Year Retrospective Review Avni Shah; Alain M. Bauza; Anton M. Kolomeyer; Paul D. Langer; Marco A. Zarbin; Neelakshi Bhagat View Presentation 4440 - D0125. Utilizing HIWA, a Scoring System of Pediatric Ocular Trauma Retrospective Reports, Analyzing Existing Literature and Informing Future Standards Andrea Honda; Paul Latkany; Monica Lorenzo; Emily Su View Presentation 4441 - D0126. Enucleation following Open Globe Injury Ananya Anne; Alain M. Bauza; Paul D. Langer; Roger E. Turbin; Marco A. Zarbin; Neelakshi Bhagat View Presentation 423. Ocular Blood Flow; Surgery and Wound Healing Moderator(s): Leopold Schmetterer (Medical University of Vienna) and Alon Harris (Indiana Univ Sch of Medicine) 8:30 AM - 10:15 AM; Exhibit / Poster Hall 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM View Session Details View Session Details 4442 - D0182. Retinal Nerve Fiber Layer Thickness is Correlated to Retrobulbar Blood Flow in Glaucoma Patients of African Descent Anne Schroeder; Alon Harris; Brent A. Siesky; Leslie A. Tobe; Nathaniel J. Kim; Annahita Amireskandari; Brian M. Marek; Lyne Racette; George J. Eckert; Ariel Tyring View Presentation 4443 - D0183. Changes in Retinal Blood Flow are Strongly Correlated to Changes in Optic Nerve Head Morphology in Patients of African Descent Leslie A. Tobe; Alon Harris; Brent A. Siesky; Lyne Racette; Darrell WuDunn; Annahita Amireskandari; Nathaniel J. Kim; Andrew H. Huck; Ariel Tyring; Miriam Zalish View Presentation 4444 - D0184. Comparison of Nebulized dorzolamide/timolol fixed combination Mist vs Drops on Retrobulbar Blood Flow, Intraocular Pressure in Glaucoma Patients Ruta Barsauskaite; Alon Harris; Ingrida Januleviciene; Lina Siaudvytyte; Vaida Diliene; Brent Siesky View Presentation 4445 - D0185. Ocular Hemodynamic Changes after Trabeculectomy in Pseudoexfoliative and Primary Open-Angle Glaucoma Vaida Diliene; Alon Harris; Ingrida Januleviciene; Lina Siaudvytyte; Ruta Barsauskaite; Brent Siesky View Presentation 4446 - D0186. Systemic Blood Pressure and Ocular Perfusion Pressure Affect Macular Thickness in Glaucoma Patients of African Descent Brian M. Marek; Alon Harris; Brent A. Siesky; Leslie A. Tobe; Ariel Tyring; Annahita Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 158 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Amireskandari; Nathaniel J. Kim; Joshua G. Paschall; George J. Eckert; Lyne Racette View Presentation 4447 - D0187. Retinal and Macular Morphology is Correlated with Retrobulbar Vascular Resistance in Diabetic Patients with Glaucoma Austin L. Gerber; Alon Harris; Brent A. Siesky; George J. Eckert; Ingrida Januleviciene; Nathaniel J. Kim; Annahita Amireskandari; Brian M. Marek; Leslie A. Tobe; Andrew H. Huck View Presentation 4448 - D0188. Blood pressure induced dynamic blood flow autoregulation in the optic nerve head of early experimental glaucoma Lin Wang; Chelsea Piper; Grant Cull; Claude F. Burgoyne View Presentation 4449 - D0189. The NO donor, isorbide-5-mononitrate alone or combined with timolol, latanoprost or dorzolamide ameliorates intraocular pressure and ocular hemodynamic in an experimental model of glaucoma in rabbits Francesco Impagnatiello; Barbara Giambene; Francesca Fabrizi; Elena Bastia; Fernando Galassi; Emanuela Masini View Presentation 4450 - D0190. Effects of diverse Nitric Oxide donation on ocular hemodynamic and intraocular pressure in normotensive rabbits Elena Bastia; Francesco Impagnatiello; Daniela Miglietta; Barbara Giambene; Emanuela Masini; Nicoletta Almirante View Presentation 4451 - D0191. Association between waveform changes in optic nerve head circulation and retinal nerve fiber layer thickness in normal-tension glaucoma patients compared to healthy subjects, measured by laser speckle flowgraphy Yukihiro Shiga; Yu Yokoyama; Toshifumi Asano; Shigeto Maekawa; Satoru Tsuda; Naoko Aizawa; Kazuko Omodaka; Morin Ryu; Toru Nakazawa View Presentation 4452 - D0192. Analysis of the Correlation Between Peripapillary Choroidal Thickness and the Nerve Fiber Layer Damage in Primary Open Angle Glaucoma Patients Nimesh Patel; Chandrasekharan Krishnan View Presentation 4453 - D0193. Change in intraocular pressure is a major determinant of retinal vein pulsation properties William Morgan; Martin Hazelton; Brigid Betz-Stablein; Philip House; Yu Dao-Yi View Presentation 4454 - D0194. Nonphysiologic nocturnal blood pressure dipping in Primary Open Angle Glaucoma (POAG) and Normal Pressure Glaucoma (NPG) patients Karin R. Pillunat; Cosima Hermann; Olga Furashova; Eberhard Spoerl; Lutz E. Pillunat View Presentation 4455 - D0195. Relation of Spontaneous Retinal Venous Pulsation and Disc Hemorrhage in Open Angle Glaucoma Mijin Kim; Tae-Woo Kim; Robert N. Weinreb; Eun Ji Lee; Je Hyun Seo; Ki Ho Park; Dong Myung Kim View Presentation 4456 - D0196. Optic Nerve Capillaries Blood Oxygenation in Normal and Primary OpenAngle Glaucoma Subjects Vasile Diaconu; Van Loc Tran View Presentation 4457 - D0197. Reduced Retinal Blood Flow is Associated with Thinner Retinal Nerve Fiber Layer in Glaucomatous Eyes with Single Hemifield Damage Mitra Sehi; Iman Goharian; Ranjith Kumar Konduru; Ou Tan; Sowmya Srinivas; Srinivas R. Sadda; David Huang; David S. Greenfield View Presentation 4458 - D0198. Optic Nerve Head Label-free Microangiography: OCT-based Correlation of Microstructure and Microvasculature in Normal & Open Angle Glaucoma Subjects lin an; Peng Li; Murray A. Johnstone; Ruikang K. Wang View Presentation 4459 - D0199. Effect of Cerebrospinal Fluid Pressure on Central Retinal Artery Hemodynamics: a Mathematical Model Lucia Carichino; Giovanna Guidoboni; Annahita Amireskandari; Brent Siesky; Alon Harris View Presentation 4460 - D0200. The effect of anthocyanins and ginko biloba extract treatment in patients with open-angle glaucoma depending on the presence of diabetes mellitus Yong Woo Lee; Seonghee Shim; Joon Mo Kim; Chul Young Choi; Ki Ho Park View Presentation 4461 - D0201. A theoretical investigation of the relationship between intraocular pressure, cerebrospinal fluid pressure, arterial blood pressure, blood flow autoregulation and retinal hemodynamics Giovanna Guidoboni; Alon Harris; Simone Cassani; Lucia Carichino; Annahita Amireskandari; Brent A. Siesky View Presentation 4462 - D0202. Effect of Trabeculectomy on Retinal Hemodynamics: Mathematical Modeling of Clinical Data Simone Cassani; Giovanna Guidoboni; Ingrida Januleviciene; Lucia Carichino; Brent Siesky; Leslie A. Tobe; Annahita Amireskandari; Alon Harris View Presentation 4463 - D0203. Effect of intraocular pressure and arterial blood pressure on oxygen saturation levels in the retina: a theoretical model Julia Arciero; Alon Harris; Giovanna Guidoboni View Presentation 4464 - D0204. Retinal Oximetry in Early Primary Open Angle Glaucoma Scott D. Lawrence; Pooja D. Jani; Kyle Billow; Jean-Claude Mwanza; Iryna A. Falkenstein View Presentation 4465 - D0205. Optic nerve head basal blood flow increases early and then progressively decreases in non-human primate experimental glaucoma Grant Cull; Chelsea Piper; Claude F. Burgoyne; Lin Wang View Presentation 4466 - D0206. Correlation between papillomacular bundle thickness (PMBT) and optic nerve blood flow in primary open-angle, including normal-pressure, glaucoma Wataru Kobayashi; Kazuko Omodaka; Kyosuke Togashi; Morin Ryu; Tetsuya Yuasa; Toru Nakazawa View Presentation 4467 - D0207. Optic Nerve Head Morphology and Retrobulbar Blood Flow; Differences between Glaucoma Patients with and without Diabetes Joshua G. Paschall; Alon Harris; Brent A. Siesky; Leslie A. Tobe; Annahita Amireskandari; Nathaniel J. Kim; Chi-Wah R. Yung; Brian M. Marek; Darrell WuDunn; John Abrams View Presentation 4468 - D0208. Glaucoma Patients with Diabetes Have Increasing Vascular Resistance in the Ophthalmic and Central Retinal Arteries Compared to Glaucoma Patients without Diabetes Nathaniel J. Kim; Alon Harris; Brent A. Siesky; Annahita Amireskandari; Joshua G. Paschall; Darrell WuDunn; Louis B. Cantor; Chi-Wah R. Yung; Leslie A. Tobe; John Abrams View Presentation 4469 - D0209. Changes in Retinal Blood Flow Correlate More Strongly with Changes in Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 159 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Optic Nerve Head Morphology in Glaucoma Patients with Diabetes Compared to Glaucoma Patients without Diabetes Annahita Amireskandari; Alon Harris; Brent A. Siesky; Nathaniel J. Kim; Brian M. Marek; Joshua G. Paschall; Louis B. Cantor; Yara P. Catoira-Boyle; John Abrams; Leslie A. Tobe View Presentation 4470 - D0210. Systemic Blood Pressure and Ocular Perfusion Pressure affect Retrobulbar Blood Flow Differently in Glaucoma Patients of European and African Descent Ariel Tyring; Alon Harris; Brent A. Siesky; Lyne Racette; Yara P. Catoira-Boyle; Annahita Amireskandari; Nathaniel J. Kim; Joshua G. Paschall; Brian M. Marek; Leslie A. Tobe View Presentation 4471 - D0211. Retinal Oximetry in Primary Open-Angle Glaucoma: Differences in Patients of African and European Descent Brent A. Siesky; Alon Harris; Lyne Racette; Louis B. Cantor; Leslie A. Tobe; Yara P. Catoira-Boyle; Chi-Wah R. Yung; Darrell WuDunn; James M. Beach View Presentation 4472 - D0212. Systemic Blood Pressure and Ocular Perfusion Pressure Affects Blood Flow to the Optic Nerve Head in Glaucoma Patients with Diabetes Andrew H. Huck; Alon Harris; Brent A. Siesky; Leslie A. Tobe; Nathaniel J. Kim; Annahita Amireskandari; Brian M. Marek; Ingrida Januleviciene; Barbara M. Wirostko; George J. Eckert View Presentation 4473 - D0213. Effects of Rho Kinase Inhibitor on mRNAs Associated with Glaucoma Progression in Human Trabecular Meshwork Cells Following Oxidative Stress Hideki Mochizuki; Junko Hirata; Yoshiaki Kiuchi View Presentation 4474 - D0214. Burden of care associated with Childhood Glaucoma: 4 year study Jacey Hanna; Lekha Ravindraraj; Robert D. Fechtner; Albert S. Khouri View Presentation 4475 - D0215. Evaluation of surface free energy of Aurolab Aqueous Drainage Implant (AADI) and its influence on cell adhesion property, in comparison with Baerveldt Implant Chidambaranathan Gowri Priya; Karuppasamy Sivakumar; Manju Pillai; Subbiah Ramaswami Krishnadas; Ravilla D. Sriram; Veerappan Muthukkaruppan View Presentation 4476 - D0216. Targeting specific TGF-β signaling pathways to prevent bleb fibrosis after glaucoma drainage device surgery Christian K. Vorwerk; Vladislavs Sokalskis; Alexander Zabelyshenskiy; Hagen Thieme; Lars Choritz View Presentation 4477 - D0217. Retrospective study of congenital glaucoma surgical treatment Hector Bello Lopez Portillo; Jesus Jimenez-Roman; Mauricio Turati-Acosta; Magdalena García-Huerta; Rafael Castañeda Diez; Felix Gil Carrasco; Cristina Isida Llerandi View Presentation 4478 - D0218. Intraocular Pressure Reduction of Modified 360-degree Suture Trabeculotomy in Intent-to-treat Eyes Daisuke Shiba; Takeshi Ono; Naoki Ozeki; Kenya Yuki; Kazuo Tsubota View Presentation 4479 - D0219. Evaluation of Dose Effect of ALK-5 Inhibitor and Controlled Delivery with Novel Pentablock Polymer in Glaucoma Filtration Surgery Hiroshi Nakamura; Jeffrey J. Dunmire; Vijaykumar Sutariya; Michael Hewit; Daniel Wehrung; Sulabh Patel; Ashim K. Mitra View Presentation 4480 - D0220. The effect of steroid and matrix metalloproteinase inhibitor on bleb survival in an experimental animal model Alastair Lockwood; Abeer Mohamed Ahmed; Ashkan Khalili; Sahar Awwad; Garima Sharma; Steve Brocchini; Peng T. Khaw View Presentation 4481 - D0221. Attenuation of Glaucoma Filtration Surgery-induced Scarring by an FDAapproved Histone Deacetylase Inhibitor, Suberoylanilide Hydroxamic Acid (SAHA) Ajay Sharma; Jacob w. Brubaker; Marcos Reyes; Jason T. Rodier; Ashish Tandon; Rajiv R. Mohan View Presentation 4482 - D0222. Surgical Outcomes of Augmented MMC Trabeculectomy After Failed Seton Surgery Jose A. Paczka; Luz A. Giorgi-Sandoval; Miriam A. Ramos-Hernandez; Jesus JimenezRoman; Arie Merikansky View Presentation 4483 - D0223. Influence of endothelin-1 in aqueous humor on IOP and filtration surgery outcome Lars Choritz; Benjamin Mahmoodi; Maren Machert; Norbert Pfeiffer; Hagen Thieme View Presentation 4484 - D0224. A NEW TECHNIQUE FOR GLAUCOMA SURGERY: SCOROLLI TRABECULECTOMY Lucia Scorolli; Enrico Meduri; Antonio De Leo; Renato Pieralberto Meduri; Edina Zere; Pier Paolo Piccaluga; Sergio Zaccaria Scalinci View Presentation 4485 - D0225. Functional and anatomic outcomes following endocyclophotocoagulation (ECP) surgery for neo-vascular glaucoma as compared to routine glaucoma care Kyle V. Marra; Sushant Wagley; Ahmed F. Omar; Jorge G. Arroyo View Presentation 4486 - D0226. Efficacy of Catheter Assisted 360° Tr abeculotomy in Primary Congenital Glaucoma (PCG) Erika Wandel; Dipali Dave; Monisha Mandalaywala Vora; Craig H. Marcus; Robert F. Rothman; Tamiesha Frempong; Daniel D. Hayes; Allison Angelilli; Janet B. Serle View Presentation 4487 - D0227. Ahmed glaucoma valve FP7 and FP8 in pediatric glaucoma: A randomized clinical trial Bruno L. Esporcatte; Camila F. Netto; Thais Tanno; Luiz Alberto S. Melo; Ivan M. Tavares; Christiane Rolim de Moura View Presentation 4488 - D0228. A model to measure surgical outflow using a two-tubed experimental glaucoma drainage device. Craig Ross; Dan Nguyen; Surinder S. Pandav; Yu Qin Li; Jonathan G. Crowston; Michael A. Coote View Presentation 4489 - D0229. Comparison of Early Post-Operative Challenges in P200 Ex-PRESS Shunts and Conventional Trabeculectomies Maheen Haque; Bret A. Hughes; Justin Tannir; Rominder Momi; Chaesik Kim View Presentation 4490 - D0230. Comparision of surgical outcomes of Express Shunt and Ahmed Valve in Neovascular Glaucoma Huseyin Kadikoy; Bret A. Hughes; Justin Tannir; Rominder Momi View Presentation 4491 - D0231. A Novel Minimally Invasive Drainage Implant (the MIDI-Arrow): One-Two Year Follow Up Paul F. Palmberg; Juan F. Batlle; Rachel Alburquerque; Adalgisa Corona-Peralta; Isabelle Riss; Richard Parrish; Esdras Arrieta; Jean-Marie A. Parel View Presentation 4492 - D0232. Surgical Outcomes in First 25 Canaloplasties and Impact of Growing Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 160 sur 222 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM 8:30 AM - 10:15 AM Experience on Complications Elisabeth P. Aponte; Jonathan Eisengart View Presentation 4493 - D0233. Review of the Success Rate of an Intraoperative Modified Bleb Revision Technique Priya Gupta; Karun S. Arora; Chun-Hao Lee; David S. Friedman View Presentation 4494 - D0234. Clinical and Tomographic Findings in Filtering Blebs Undergoing Digital Compression Miriam A. Ramos-Hernandez; Miriam A. Ramos-Hernandez; Elia Chavez; Luz A. GiorgiSandoval; Jose A. Paczka View Presentation 4495 - D0235. Cyclodialysis incidence in anterior segment surgery in an Ophthalmology Referral Center Rodrigo Bolanos; Alejandro Navas; Enrique O. Graue-Hernández; Arturo J. RamirezMiranda; Jasbeth Ledesma Gil View Presentation 4496 - D0236. Optimal administration route of bevacizumab after glaucoma filtration surgery Karolien P. Hollanders; Tine Van Bergen; Davine Sijnave; Sarah Van de Velde; Evelien Vandewalle; Lieve K. Moons; Ingeborg Stalmans View Presentation 424. Genetics I Moderator(s): John Fingert (University of Iowa) and Andrew Lotery (University of Southampton) 11:00 AM - 12:45 PM; 6B 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM 4497. Genome-wide Association Study and Meta-Analysis of Intraocular Pressure in Primary Open-Angle Glaucoma Cases and Controls in the NEIGHBOR, GLAUGEN and AMD-MMAP Studies Sayoko E. Moroi; Ayse B. Ozel; David M. Reed; Kari E. Branham; Michael A. Hauser; Louis R. Pasquale; Janey L. Wiggs; Julia E. Richards; Jun Z. Li View Presentation 4498. Molecular mechanisms in Primary Glaucoma: POAG-associated variant disrupts microRNA regulation of CDKN2B expression Terry Gaasterland; Amy N. Dubinsky; Albert R. La Spada; Kaweh Mansouri; Karl H. Willert; Douglas E. Gaasterland; Michael A. Hauser; Louis R. Pasquale; Janey L. Wiggs; Robert N. Weinreb View Presentation 4499. Runs of Homozygosity Across the Whole Genome Suggests two Novel Genes in Primary Congenital Glaucoma Subhabrata Chakrabarti; Sriparna Ganguly; Meha Kabra; Anil K. Mandal; Sirisha Senthil; Inderjeet Kaur; Partha P. Majumder View Presentation 4500. Genetic factors and pathways affecting retinal nerve fiber layer thickness Cristina Venturini; Pirro G. Hysi; Abhishek Nag; Ekaterina Yonova; Jie Jin Wang; Tien Y. Wong; Paul R. Healey; Paul Mitchell; Christopher J. Hammond; Ananth C. Viswanathan View Presentation 4501. The role of SIX6 in primary open-angle glaucoma Michael A. Hauser; Megan Ulmer; Yangfan Liu; Erica Davis; Nicholas Katsanis; Yutao Liu; Louis R. Pasquale; Janey L. Wiggs; Allison E. Ashley-Koch; R Rand Allingham View Presentation 4502. A genome-wide association study of intra-ocular pressure identifies a novel association in the gene FAM125B in the TwinsUK cohort Abhishek Nag; Pirro G. Hysi; Cristina Venturini; Ekaterina Yonova; Katie M. Williams; Christopher J. Hammond View Presentation 4503. Identification of further novel genome wide significant loci for open angle glaucoma blindness utilizing the Australian and New Zealand Registry of Advanced Glaucoma Jamie E. Craig; Alex W. Hewitt; Stuart Graham; Paul R. Healey; Robert J. Casson; Paul Mitchell; John Landers; Stuart MacGregor; David A. Mackey; Kathryn P. Burdon View Presentation 425. AMD: Novel and Combination Therapies Moderator(s): Susanne Binder (Rudolf Foundation Clinic) and Pravin Dugel (Retinal Consultants of Arizona, Ltd) 11:00 AM - 12:45 PM; 6C 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 11:00 AM - 11:15 11:15 AM - 11:30 View Session Details 4504. Anti-VEGF Gene Therapy for Wet AMD: Safety and Tolerability of Subretinal Delivery in a Phase I/II Clinical Trial Ian Constable; Cora Pierce; Sendhil K. Somasundaram; May Lai; Thomas W. Chalberg; Mark S. Blumenkranz; Richard Samulski; Elizabeth P. Rakoczy View Presentation 4505. Phase I, Masked, Placebo-Controlled, Single and Multiple Ascending Intravenous Dose Studies Evaluating Systemic and Ocular Safety, Tolerability, and Visual Acuity Effects of RN6G (PF-04382923) in Subjects with Dry, Age-Related Macular Degeneration (ARMD) Brian B. Berger; Pamela D. Garzone; Ivana Gunderson; Philip M. Fanning; Gilbert Wong; Kai H. Liao; Steven Y. Hua; John Lin View Presentation 4506. A Phase 2 Double-masked, Placebo-controlled, Dose Ranging Study of Emixustat Hydrochloride (ACU-4429) in Subjects with GA Associated with Dry AMD Pravin U. Dugel; Roger L. Novack; Karl G. Csaky; Preston p. Richmond; David G. Birch; Ryo Kubota View Presentation 4507. Photodynamic Therapy vs Combination Therapy in Polypoidal Choroidal Vasculopathy: Changes of Aqueous Vascular Endothelial Growth Factor Meeyon Lee; Won Ki Lee View Presentation 4508. Twelve Months Results Comparing Ranibizumab or Bevacizumab Treatment in Patients with Neovascular Age-related Macular Degeneration(AMD) Multicenter AntiVEGF Trial in Austria The Manta Study Susanne Binder; Ilse Krebs; Leopold Schmetterer View Presentation 4509. Long-Term and Lasting Outcomes of Combination Treatment for Age-Related Macular Degeneration with Photodynamic Therapy and Intravitreal Injection of AntiVascular Endothelial Growth Factor Colleen M. McLellan; Rosemary Silva-Garcia; Kent W. Small View Presentation 426. Macular Disease other than AMD II Moderator(s): William Mieler (University of Illinois at Chicago) and K Bailey Freund (Vitreous Retina Macula Consultants NY) 11:00 AM - 12:45 PM; 6E AM View Session Details View Session Details 4510. Occult Central Serous Chorioretinopathy K Bailey Freund; David Warrow; Roberto Gallego-Pinazo; Quan V. Hoang View Presentation 4511. Effect of Somatostatin on the expression of tight junctions and urokinase plasminogen activator receptor in human retinal pigment epithelial cells Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 161 sur 222 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM Alex Fonollosa; Joseba Artaraz; Agustin Martinez-Berriotxoa; Elena Vecino View Presentation 4512. Selective Laser Photocoagulation of Peripheral Non-perfused Retinal Areas May Improve the Vision in Patients with Central Retinal Vein Occlusion Treated with Ranibizumab Matus Rehak; Annegret Franke; Peter M. Wiedemann View Presentation 4513. Macular Bruchs Membrane Defects and Axial Length: Association with Gamma Zone and Delta Zone in Peripapillary Region Jost B. Jonas; Kyoko Ohno-Matsui; Richard F. Spaide; Leonard Holbach; Songhomitra Panda-Jonas View Presentation 4514. Treatment Experience with Intravitreal Aflibercept Injection (IAI) After Switching to PRN Dosing in Patients with Macular Edema Secondary to Central Retinal Vein Occlusion (CRVO) David M. Brown; Frank G. Holz View Presentation 4515. Two-Year Results of the COPERNICUS Study Evaluating Intravitreal Aflibercept Injection (IAI) for Macular Edema Secondary to Central Retinal Vein Occlusion (CRVO) W. Lloyd Clark View Presentation 4516. Eighteen-Month Results of the GALILEO Study Evaluating Intravitreal Aflibercept Injection (IAI) for Macular Edema Secondary to Central Retinal Vein Occlusion (CRVO) Yuichiro Ogura; Jean-Francois Korobelnik; Johann Roider; Robert Vitti; Frank G. Holz; Florian Hiemeyer; Brigitte Stemper ; Oliver Zeitz; Rupert Sandbrink View Presentation 427. Ocular Immune Responses View Session Details Moderator(s): Holly Rosenzweig (Portland VA Medical Center) and Thomas Langmann (University of Cologne) 11:00 AM - 12:45 PM; 606/607 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM 4517. Loss of MicroRNA-124 and MicroRNA-126 expression regulates inflammatory microglial activation in inherited retinal degeneration Thomas Langmann; Christoph Moehle; Marcus Karlstetter; Bernhard H. Weber View Presentation 4518. Mice lacking TNFR1 develop less angiogenesis during late stage experimental autoimmune uveoretinitis (EAU) Madeleine Stimpson; Jian Liu; David A. Copland; Tarnjit K. Khera; Andrew D. Dick View Presentation 4519. Differential effects of TLR-3 activated RPE on retinal microglia and blood-derived monocytes Alexa K. Klettner; Timothy Hamann; Sebastian Wilker; Christin Berg; Karen Schlüter; Ralph Lucius; Mentlein Rolf; Johann Roider View Presentation 4520. Demonstration of Donor T cell Recruitment and Correlation with Inflammatory Cytokine Presence in Experimental Ocular Graft-versus-Host Disease Samantha Herretes; Juan C. Murillo; Duncan Ross; Henry Barreras; Yaohong Tan; Ali M. Saeed; Astrid Gonzalez; Carolina Betancurt; Robert B. Levy; Victor L. Perez View Presentation 4521. Monophasic PDSAg-induced EAU dominates over relapsing R14-induced EAU Ulrike Kaufmann; Maria Diedrichs-Möhring; Gerhild Wildner View Presentation 4522. Inhibition of Vascular Endothelial Growth Factor Ameliorates Ocular Allergy in the Murine Model Daniel R. Saban; Reza Dana; Hyun Soo Lee; Tomas Blanco View Presentation 4523. Translational Modeling of Calpain-5 Vitreoretinopathy Mechanisms in Mice Vinit B. Mahajan; Katherine J. Wert; Jessica M. Skeie; Stephen H. Tsang View Presentation 428. Uveal Melanoma: Experimental Therapeutics Moderator(s): Hans Grossniklaus (Emory University), Sarah Coupland (Univ of Liverpool/Sydney Jones Library) and Arun Singh (Cole Eye Institute) 11:00 AM - 12:45 PM; 608 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM View Session Details 4524. Microphthalmia-associated transcription factor (MITF) and Steroid Receptor Coactivator (SRC)-3 cooperate to promote proliferation, survival and metabolism in Gαmutant uveal melanoma (UM) cells Vassiliki Poulaki; Sue Anne Chew; Bin He; Vijay Kumar Eedunuri; Martine M. Jager; Bert W. O'Malley; Nicholas Mitsiades View Presentation 4525. Uveal Melanoma Cells Are Inhibited by AICAR Partially Through Activation of AMP-Dependent Kinase Ahmad Al Moujahed; Fotini Nicolaou; Thanos D. Papakostas; Joan W. Miller; Evangelos S. Gragoudas; Demetrios Vavvas View Presentation 4526. SRPK1 Inhibition, As A Way Of Targeting Pro-Angiogenic VEGF-A Production In Ocular Tumours Melissa V. Gammons; Sarah E. Coupland; Andrew D. Dick; David O. Bates View Presentation 4527. Targeting Uveal Melanoma Response to Hypoxia Dudi Shneor; Alik Honigman; Jacob Pe'er; Shahar Frenkel View Presentation 4528. Efficacy of A Novel Anti-tumor Agent KCN1 in the Control of Ocular Melanoma In vitro and In vivo Qing Zhang; Hua Yang; Stefan Kaluz; Erwin G. Van Meir; Hans E. Grossniklaus View Presentation 4529. NFkB Inhibition in Uveal Melanoma – Contrariety of in vitro vs. in vivo Results Shahar Frenkel; Dudi Shneor; Jacob Pe'er; Alik Honigman View Presentation 4530. Identification of regulators of uveal melanoma metastasis through whole exome sequencing Sarah Lake; Bertil E. Damato; Helen Kalirai; Lisa Olohan; Xuan Liu; Sarah E. Coupland View Presentation 429. A Global View of Posterior Capsule Opacification - Minisymposium Moderator(s): Michael Wormstone (University of East Anglia), Melinda Duncan (University of Delaware) and Steven Bassnett (Washington Univ Sch of Med) 11:00 AM - 12:45 PM; 609 View Session Details Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary 11:00 AM - 11:05 Introduction Include in Itinerary 11:05 AM - 11:30 4531. Polymers, Barriers and Haptics: The Development of IOLSs in the Prevention of PCO David Spalton View Presentation 4532. Differentiation in the Lens: Implications for PCO Linda Musil View Presentation Include in Itinerary AM AM 11:30 AM - 11:55 AM Include in Itinerary 28/03/2013 Abstract Central Page 162 sur 222 11:55 AM - 12:20 PM 12:20 PM - 12:45 PM 4533. Lens Cell/ECM Interactions in PCO Melinda K. Duncan View Presentation 4534. TGFbeta and PCO: Why Old Bags Wrinkle Michael Wormstone View Presentation 430. Physiologic Vascularization in Retinopathies Moderator(s): Azza El-Remessy (University of Georgia) and Alan Stitt (Queens University Belfast) 11:00 AM - 12:45 PM; 611-614 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM 11:00 AM - 11:15 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM 11:00 AM - 11:15 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM View Session Details View Session Details 4542. Does government assistance improve access for low-income individuals to eye care providers? Chris J. Hong; Graham E. Trope; Yvonne M. Buys; Barbara E. Robinson; Yaping Jin View Presentation 4543. The Association of Vision Loss with Work Status in the United States Cheryl Sherrod; Kevin D. Frick; Pradeep Y. Ramulu View Presentation 4544. Despite Possessing Health Insurance, Large Disparities Exist in Likelihood of Visits to Eye Care Providers Across U.S. Sociodemographic Groups Patricia A. Ple-plakon; Chris A. Andrews ; David C. Musch; Paul P. Lee; Joshua D. Stein View Presentation 4545. The global burden of potential productivity loss from presbyopia Susan M. Joy; Kevin D. Frick; Kovin S. Naidoo; David A. Wilson; Brien A. Holden View Presentation 4546. An Evaluation of Non-Physician Educators' Role In Enhancing Cataract Patient’s Surgical Knowledge and Satisfaction Paula Anne Newman-Casey; Sathya Ravilla; Haripriya Aravind; Vinoth Palanichamy; Manju Pillai; Vijayakumar Balakrishnan; Alan L. Robin View Presentation 4547. Cohort- and age-specific effects of annual mass drug administration on prevalence of trachoma: a longitudinal study in rural Tanzania Nakul Shekhawat; Beatriz E. Munoz; Harran A. Mkocha; Sheila K. West View Presentation 4548. Time-Motion Analysis of Clinical Nursing Documentation during Implementation of an Electronic Operating Room Management System for Ophthalmic Surgery Sarah Read-Brown; Anna S. Brown; Thomas R. Yackel; Dongseok Choi; Daniel C. Tu; David S. Sanders; Michael F. Chiang View Presentation 432. Refractive Errors, Myopia II Moderator(s): Arthur Bradley (Indiana University) and Frank Schaeffel (Ophthalmic Research Institute) 11:00 AM - 12:45 PM; TCC LL 4/5 AM Include in Itinerary 4535. Inhibiting the Ras Pathway Prevents Ocular Neovascularization by Repressing Tip Cell Sprouting Peter D. Westenskow; Toshihide Kurihara; Edith Aguilar; Mariah Webb; Carli M. Wittgrove; Stacey K. Moreno; Martin Friedlander View Presentation 4536. Endothelial Progenitor Cells in Bone Marrow, Blood, and Retina Respond Dynamically to Murine Oxygen-Induced Retinopathy Bliss E. O'Bryhim; R. Sid White; Robert C. Symons View Presentation 4537. Neuronal Sirtuin1 mediates retinal vascular regeneration in retinopathy Jing Chen; Aimee Juan; Christian G. Hurst; Dorothy T. Pei; Jean-Sebastien Joyal; Lucy Evans; Zhenghao Cui; Andreas Stahl; Przemyslaw Sapieha; Lois E. Smith View Presentation 4538. Vascular Protective Effects of Candesartan In Ischemic Retinopathy Azza B. El-Remessy; Ahmed Y. Shanab; Suraporn Matragoon; Susan C. Fagan View Presentation 4539. Senescent endothelial progenitor cells show impaired vasoregenerative capacity in the ischemic retina Emma Reid; Reinhold J. Medina; Michelle O'Doherty; Christina L. O'Neill; Sarah Wilson; Jasenka Guduric-Fuchs; Jessica Neisen; David J. Waugh; David A. Simpson; Alan W. Stitt View Presentation 4540. Lack of Cyp1B1 Promotes the Proliferative and Migratory Phenotype of Perivascular Supporting Cells Nader Sheibani; Tammy L. Palenski; Christine M. Sorenson View Presentation 4541. Laminin Regulation of Retinal Vascularization: Role in Astrocyte Migration and Differentiation William J. Brunken; Galina Bachay; Saptarshi Biswas; Gopalan Gnanaguru View Presentation 431. Eye Care: Who’s Not Getting It and Why It Matters Moderator(s): Pradeep Ramulu (Wilmer Eye Inst/Johns Hopkins) and Nakul Shekhawat (Vanderbilt Univ School of Medi) 11:00 AM - 12:45 PM; 615-617 AM Include in Itinerary View Session Details 4549. The impact of Spherical Aberration, Stiles Crawford Apodization and Spatial Frequency on wavefront-based and subjective refractions Renfeng Xu; Arthur Bradley; Larry N. Thibos; Gildas Marin; Martha Hernandez View Presentation 4550. Impact of Primary and Secondary Spherical Aberration on Predicted Peripheral Image Quality Amanda C. Kingston; Geunyoung Yoon View Presentation 4551. Peripheral Wavefront Aberrations of Accommodating Human Eye Tao Liu; Larry N. Thibos View Presentation 4552. 1 Changes in Ocular Biometrics and Refraction during Near Work in Downward Gaze over Time Atanu Ghosh; Michael J. Collins; Brett A. Davis; Scott A. Read; Fan Yi; Payel Chatterjee View Presentation 4553. Effect of Accommodation on Peripheral Refraction Jason Shen; Frank Spors View Presentation 4554. School-Age Myopic Shift in Hyperopic Children with Infantile Esotropia and Peripheral Myopia Eileen E. Birch; Simone Li; Sarah E. Morale; Reed M. Jost; Vidhya Subramanian; Donald O. Mutti View Presentation 433. Stroma Keratocytes, Development and Dystrophies Moderator(s): Albert Jun (Johns Hopkins Wilmer Eye Inst) and Sophie Deng (Jules Stein Eye Institute) View Session Details Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary 28/03/2013 Abstract Central Page 163 sur 222 11:00 AM - 12:45 PM; TCC 303 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM 4555. Wnt/b-catenin canonical signaling in corneal keratocytes regulates epithelium stratification through repressing Bmp4/Mapk pathway Yujin Zhang; Lung-Kun Yeh; Winston W. Kao; Chia-Yang Liu View Presentation 4556. Peptide Amphiphiles as Versatile Substrates for Oriented Cell Adhesion and Proliferation of Human Cornea Stromal Keratocytes Ricardo M. Gouveia; Valeria Castelletto; Ian Hamley; Che J. Connon View Presentation 4557. Limbal Biopsy As a Source of Stem Cells for Autologous Stromal Cell-based Therapy Sayan Basu; Martha L. Funderburgh; James L. Funderburgh View Presentation 4558. Mass Spectrometric – Based Proteomic Analysis of TGFBI Corneal Dystrophies Aarika Menees; Surendra Dasari; Ahmet Dogan; Sanjay V. Patel; Keith H. Baratz; Jason D. Theis; Julie A. Vrana; Diva R. Salomao View Presentation 4559. Investigation of Gene Therapy Using Immortalized Cells Derived from a Gelatinous Drop-Like Corneal Dystrophy Patient Koji Kitazawa; Satoshi Kawasaki; Keita Aoi; Katsuhiko Shinomiya; Akira Matsuda; Toshinari Funaki; Mina Nakatsukasa; Junji Hamuro; Akira Murakami; Shigeru Kinoshita View Presentation 4560. A Family-based Investigation of the Role of TCF4 Trinucleotide Repeat Expansion in Fuchs Endothelial Corneal Dystrophy (FECD) Keith H. Baratz; Ross A. Aleff; Yi-Ju Li; Malinda L. Butz; Simon G. Gregory; Gordon K. Klintworth; W. Edward Highsmith; Natalie A. Afshari; Eric D. Wieben View Presentation 4561. AGBL1 implicated in the pathogenesis of late-onset FCD and interacts with TCF4 John D. Gottsch; Shivakumar Vasanth; Nicholas Katsanis; S. Amer Riazuddin View Presentation 434. Genetics, Development and Aging Moderator(s): Rachel Wong (University of Washington) and Anand Swaroop (National Eye Institute) 11:00 AM - 12:45 PM; TCC 304 11:00 AM - 11:00 AM 11:00 AM - 11:15 AM 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM 11:00 AM - 11:15 11:15 AM - 11:30 AM 11:30 AM - 11:45 AM 11:45 AM - 12:00 PM 12:00 PM - 12:15 PM 12:15 PM - 12:30 PM 12:30 PM - 12:45 PM Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Fuerst? Stafford? Polosa? all with scores=2; Include in Itinerary 4562. Distinct Roles Of Activity-Dependent And Independent Mechanisms In Regulating The Bipolar Cell Inputs Onto Retinal Ganglion Cells Haruhisa Okawa; Luca Della Santina; Greg Schwartz; Daniel Kerschensteiner; Fred Rieke; Rachel O. Wong View Presentation 4563. Following the Ontogeny of Retinal Waves: Pan-Retinal Recordings of Population Dynamics in the Neonatal Mouse Evelyne Sernagor; Matthias H. Hennig; Alessandro Maccione; Mauro Gandolfo; JensOliver Muthmann; Stephen J. Eglen; Luca Berdondini View Presentation 4564. Dendrites of melanopsin ganglion cells transiently extend into the outer retina in early postnatal development Jordan M. Renna; Deepa K. Chellappa; Maureen E. Estevez; David M. Berson View Presentation 4565. Epigenetic maintenance of adult cone photoreceptors Volker Busskamp; Jacek Krol; Karl Farrow; Josephine Juettner; Dasha Nelidova; Vithiyanjali Sothilingam; Marina Garcia Garrido; Mathias W. Seeliger; Witold Filipowicz; Botond Roska View Presentation 4566. Down-regulation of oxidative phosphorylation genes and up-regulation of protein degradation pathway genes are a hallmark of aging rod photoreceptors in mouse retina Tiziana Cogliati; Jennifer Barb; Norimoto Gotoh; Matthew Brooks; Linn Gieser; Neel Gupta; Rafael Villasmil; Inhan Lee; Peter J. Munson; Anand Swaroop View Presentation 4567. Synaptic localization but not specificity is mediated by Down Syndrome Cell Adhesion Molecule Peter G. Fuerst; Shuai Li; Dee Schramm View Presentation 4568. Developmental changes in subunit- and pathway-specific expression of NMDA receptors in direction-selective ganglion cells Ben Stafford; Kwoon Y. Wong; Jonathan B. Demb View Presentation Include in Itinerary 435. Neuro-Ophthalmology: Novel Treatments and Mechanisms of Disease Moderator(s): Yaping Liao (Byers Eye Institute at Stanford) and Prem Subramanian (Wilmer Eye Institute) 11:00 AM - 12:45 PM; TCC 305 AM View Session Details Include in Itinerary View Session Details 4569. MTS-AAV Delivery of Human ND4 in the Mouse Eye John Guy; Hong Yu; Arpit Mehta; Gaofeng Wang View Presentation 4570. Retinal ganglion cells exhibit spontaneous hyperactivity and abnormally sustained light-evoked responses in in a mouse model of traumatic brain injury Matthew Harper; Frederick R. Blodi; Malini Shankar; Elena Hernandez-Merino; Helga Kecova; Laura Dutca; Randy H. Kardon; Steven F. Stasheff View Presentation 4571. TrkB Neurotrophin Receptor Activation with Pharmacophore as Possible Treatment for Anterior Ischemic Optic Neuropathy Yaping J. Liao; Gun Ho Lee; Jeffrey Ma; Tao Yang; Chandrani Chakraborty; Ben Barres; Frank Longo; M. Ali Shariati View Presentation 4572. Genotype-retinal phenotype correlations in infantile nystagmus Mervyn G. Thomas; Viral Sheth; Rebecca J. McLean; Frank A. Proudlock; Gail Maconachie; Susanne Kohl; Wai-Man Chan; Caroline Andrews; Elizabeth C. Engle; Irene Gottlob View Presentation 4573. Visual outcomes of the surgical treatment of idiopathic intracranial hypertension Prem S. Subramanian; Pedro Fonseca; Neil R. Miller; Daniele Rigamonti View Presentation 4574. Treatment of Leber's hereditary optic neuropathy (LHON): Results using a novel quinone, EPI-743 Carlos F. Chicani; Edward R. Chu; Fred N. Ross-Cisneros; Shellee Rockwell; Katsuyuki Murase; Martin Thoolen; Guy Miller; Alfredo A. Sadun View Presentation 4575. A Phase I Open Label, Dose Escalation Trial Of QPI-1007 Delivered By A Single Intravitreal (IVT) Injection To Subjects With Low Visual Acuity And Acute Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION) Andrew N. Antoszyk; Bradley Katz; Rishi Singh; Rabia Gurses-Ozden; Shai S. Erlich; Daniel Rothenstein; Nir Sharon; Jennifer Hodge; Leonard A. Levin; Neil R. Miller View Presentation Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 164 sur 222 436. AMD I, BI Moderator(s): Aparna Lakkaraju (University of Wisconsin-Madison) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM Include All in Itinerary 4576 - A0095. Autophagy disregulation in the retina during aging and neurodegeneration Enrique J. de la Rosa; Natalia Rodriguez-Muela; Hiroshi Koga; Lucia Garcia-Ledo; Pedro de la Villa; Ana M. Cuervo; Patricia Boya View Presentation 4577 - A0096. High glucose activates ChREBP-mediated HIF-1α and VEGF expression in human RPE cells under normoxia Min-Lee Chang; Chung-Jung Chiu; Fu Shang; Allen Taylor View Presentation 4578 - A0097. AMD-associated silent polymorphisms in HtrA1 ameliorate IGF-1 antagonism Sarah Melissa P. Jacobo; Margaret M. DeAngelis; Andrius Kazlauskas View Presentation 4579 - A0098. Differences in Reactive Oxygen Species (ROS) Production and Expression of Genes from the Complement and Inflammatory Pathways Between H and K Haplogroup Cybrids Javier Cáceres del Carpio; Mohamed Tarek; Claudio A. Ramirez; Payam Falatoonzadeh; Marilyn Chwa; Deepika Malik; S Michal Jazwinski; Miceli V. Michael ; Baruch D. Kuppermann; Cristina M. Kenney View Presentation 4580 - A0099. Stimulation of Semaphorin3E/PlexinD1 pathway has anti-angiogenic effect in experimental model of choroidal neovascularization Kenji Suda; Congrong Guo; Akio Oishi; Shinya Ikeda; Nagahisa Yoshimura View Presentation 4581 - A0100. Adiponectin Peptide II (APNpII) effect on human ARPE-19 cells Puran S. Bora; Nalini S. Bora; Valeriy V. Lyzogubov View Presentation 4582 - A0101. Isoform-specific interactions between human apolipoprotein E and amyloid-beta in the retinal pigment epithelium Kimberly A. Toops; Jin Xu; Aparna Lakkaraju View Presentation 4583 - A0102. Effects of the absence of both complement factor H and apolipoprotein E on VEGF expression, MMP2/9 activity and caspase-1 Laura Garcia-Garcia; Patricia Fernandez; Sergio Recalde; Maite Moreno-Orduña; Vanessa Fernandez-Garcia; Alfredo Garcia-Layana View Presentation 4584 - A0103. Surface plasmon resonance indicates that complement factor H, C3b and native properdin bind to carboxyethylpyrrole-adducted BSA Lisa Kuttner-Kondo; Viviana P. Ferreira; Claudio Cortes; Satya P. Yadav; Joe G. Hollyfield View Presentation 4585 - A0104. The aging retina: Macula-less rat and macula-bearing monkey retinae exhibit common age-related changes in their retinal proteins Michael R. Boehm; Sonja Mertsch; Harutyun Melkonyan; Solon Thanos View Presentation 4586 - A0105. Gene expression profile of Retinal Pigment Epithelium derived ARPE-19 cells under serum starvation Sanghamitra Mishra; Katherine M. Peterson; Alan E. Berger; Graeme J. Wistow View Presentation 4587 - A0106. HSPA5 - a possible new contributing gene in atrophic age-related macular degeneration Sumana Chintalapudi; Yin H. Chan Lau; Shwetapadma Sahu; Monica M. Jablonski View Presentation 4588 - A0107. Quercetin Inhibits H2O2 Stimulated PEDF and FGF2 Synthesis in hRPE Cells Nandita Anand; Piyush C. Kothary; Monte A. Del Monte View Presentation 4589 - A0108. AMD-like phenotypes in transgenic mice over-expressing BMP4 in RPE Danhong Zhu; Jing Xu; Xuemei Deng; Jamie Hsiung; Stephen J. Ryan; David R. Hinton View Presentation 4590 - A0109. Vitamin D Status and Subretinal Fibrosis in Neovascular Age-Related Macular Degeneration Amardeep Singh; Mads K. Falk; Yousif Subhi; Torben L. Sørensen View Presentation Include in Itinerary 4591 - A0110. Cd46 -/- Mouse as a Model of Dry-type Age-related Macular Degeneration Include in Itinerary Valeriy V. Lyzogubov; Xiaobo Wu; Grant Kolar; Puran S. Bora; John P. Atkinson; Nalini S. Bora View Presentation 4592 - A0111. Tissue Inhibitor of Metalloproteinase-3 (TIMP3) Induces Endothelial Apoptosis via MMP- and Caspase-Independent Mechanisms Jian H. Qi; Bela Anand-Apte View Presentation 4593 - A0112. Localization of mechanotransduction channels in the trabecular meshwork of glaucomatous DBA/2J mice Phi Ho; Vu T. Tran; Lais Cabrera; Sanjoy K. Bhattacharya View Presentation 4594 - A0113. CTRP5 over-expression in RPE cells leads to loss of RPE cell adhesion and retinal degeneration in wild-type mice Astra Dinculescu; Seok-Hong Min; Wen-Tao Deng; Jie Li; Renee C. Ryals; Rachel M. Stupay; Ping Zhu; Bhubanananda Sahu; Radha Ayyagari; William W. Hauswirth View Presentation 437. Translational Approaches in AMD and DR Moderator(s): Ruth Caldwell (Georgia Health Sciences University) and Alfred Lewin (University of Florida) 11:00 AM - 12:45 PM; Exhibit / Poster Hall 11:00 AM - 12:45 PM View Session Details View Session Details 4595 - A0146. Not age but the rate of aging drives the pathogenesis of age related macular degeneration in primates Peter Gouras; Lena Ivert; Martha Neuringer; Julie Mattison View Presentation 4596 - A0147. The dual PPAR-α/γ agonist aleglitazar attenuates retinopathy in streptozotocin diabetic rats Raul de la Flor; Matthew B. Wright; Anthony P. Adamis; Jason S. Ehrlich; David T. Shima View Presentation 4597 - A0148. Overactive Arginase Causes Mitochondrial Dysfunction and Premature Endothelial Cell Senescence during Diabetic Retinopathy Ruth B. Caldwell; S.Priya Narayanan; Modesto A. Rojas; Tahira Lemtalsi; Zhimin Xu; Kanjana Jittiporn; Erica Schenhals; Robert W. Caldwell; David J. Fulton View Presentation 4598 - A0149. Potential beneficial effects of carotenoids on diabetic retinopathy Renu A. Kowluru; Qing Zhong; Julia M. Santos; Mangayarkarasi ThandampallayamAjje; Douglas Putt; Dennis L. Gierhart View Presentation 4599 - A0150. The Impact on Vision and Regression of Retinal Neovascularization of Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include All in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary Include in Itinerary 28/03/2013 Abstract Central Page 165 sur 222 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM 11:00 AM - 12:45 PM Anti-VEGF Induction in Combination with Quarterly Anti-VEGF Maintenance or Selective PRP versus Standard PRP Victor H. Gonzalez View Presentation 4600 - A0151. Matrix metalloproteinase-9 regulates angiogenic and vasculogenic factors in diabetic retina Ghulam Mohammad; Ahmed Abu El-Asrar View Presentation 4601 - A0152. Subtoxic Dosage of Methylglyoxal Stimulated Production of UrokinaseType Plasminogen Activator by Retinal Pigment Epithelial Cells Anthony Sclafani; Dan-Ning Hu; Tommaso Vagaggini; Steven A. McCormick View Presentation 4602 - A0153. microRNA-30a Antagonism Inhibits Ras Signaling and Prevents Neovascularization Carli M. Wittgrove; Peter D. Westenskow; Toshihide Kurihara; Edith Aguilar; Stacey K. Moreno; Martin Friedlander View Presentation 4603 - A0154. Ranibizumab and Bevacizumab Decrease Macular Ganglion Cell Complex (GCC) Thickness Measured with Fourier-Domain Optical Coherence Tomography in Age-Related Macular Degeneration (AMD) Nalin J. Mehta; Hugo Quiroz-Mercado; Michael J. Sinai; Kelly A. Soules; Anjali N. Mehta; Shulamit Schwartz View Presentation 4604 - A0155. A new mouse model of dry form AMD Haoyu Mao; Alfred S. Lewin; Mandy Conners View Presentation 4605 - A0156. Serine/Arginine-Rich Protein Kinase Blockade Attenuates Choroidal Neovascularization Zhenyu Dong; Kousuke Noda; Atsuhiro Kanda; Junichi Fukuhara; Ryo Ando; Miyuki Murata; Wataru Saito; Masatoshi Hagiwara; Susumu Ishida View Presentation 4606 - A0157. Osteopontin (OPN) is Present in Drusen and Basal Deposits in Human Eyes with Age-Related Macular Degeneration (AMD) Amanda Bednar; Mayur Choudhary; Peter Saloupis; Alan D. Proia; Goldis Malek View Presentation 4607 - A0158. The Role of Abnormal Blood Flow in Age-Related Macular Degeneration Luis Alarcon-Martinez; Hector Rieiro; Tugba Demirci; Rocio Leal-Campanario; Susana Martinez-Conde; Stephen L. Macknik View Presentation 4608 - A0159. RPE, Bruch’s membrane changes in rabbit eyes and a human eye with retinal photoxicity Mehmet Koray Sevinc; Uzeyir Erdem; Ayhan Kubar; Emin Oztas View Presentation 4609 - A0160. Inflammatory monocytes accumulate in atrophic age-related macular degeneration Sophie Lavalette; Serge Camelo; Olivier Levy; William Raoul; Bertrand Calippe; Xavier P. Guillonneau; Christophe Combadière; Florian Sennlaub View Presentation 4610 - A0161. Cell growth inhibtion in HPV 18 positive uveal melanoma cells by E6/E7 siRNA Xianqun Fan; Renbing Jia View Presentation 4611 - A0162. Aflibercept is internalized by retinal microvascular endothelial cells Heidrun L. Deissler; Gabriele E. Lang View Presentation 4612 - A0163. Therapeutic Efficacy of Adipose Stromal Cells to Protect the Retinal Neurons and Vasculature in Rat Retinal Ischemia-reperfusion Injury Model Chandrika Abburi; Adam J. Cantor; Sergio Caballero; Raj Maturi; Timothy S. Kern; Maria B. Grant; Keith L. March; Gangaraju Rajashekhar View Presentation 4613 - A0164. Lp-PLA2 is a potential therapeutic target in diabetic macula edema Paul Canning; Josephine V. Glenn; Vivien Prise; David C. Gale; Alan W. Stitt; Peter S. Adamson View Presentation 4614 - A0165. Differential impairment of rod and cone pathways in streptozotocininduced diabetic mice ilaria piano; Antonella Caputo; Elena Novelli; Luigi A. Cervetto; Claudia M. Gargini View Presentation 4615 - A0166. Comparative Ocular Tissue Distribution Kinetics of the Visual Cycle Modulator (VCM) Emixustat-HCl in Rats, Beagle Dogs, and Cynomolgus Monkeys Terry Podoll; Suliman Al-Fayoumi; Elizabeth Prescott; John W. Chandler; Ryo Kubota View Presentation 4616 - A0167. Systemic erythropoietin and its role in diabetic retinopathy Sofija Davidovic; Slobodanka Latinovic View Presentation 4617 - A0168. Chemical Screens in Zebrafish Identify Novel Inhibitors of Retinal Neovascularisation in Mouse Breandan N. Kennedy; Yolanda Alvarez; Miriam Tosetto; Claire Kilty; Temitope Sasore; Carmel M. McVicar; Alan W. Stitt; Jacintha O'Sullivan; Alison L. Reynolds View Presentation 4618 - A0169. EVALUATION OF ANTIANGIOGENIC EFFECT OF SINTETIC SMALL FRAGMENTS OF PEDF Andrea R. Carvalho; Josep Badal; Miguel A. Zapata; Anna Salas Torras; Laura N. Distefano; Jose Garcia-Arumi View Presentation 4619 - A0170. A novel Erythropoietin-derived peptide regulates Endothelial Progenitor Cell (EPC) mediated retinal vasorepair Olivia E. O'Leary; Emma Reid; Carmel M. McVicar; Michael Brines; Anthony Cerami; Reinhold J. Medina; Derek P. Brazil; Alan W. Stitt View Presentation 4620 - A0171. Effect of HMG-CoA reductase inhibitor(statins) on the expression of catalase in human retinal pigment