May 201 6

1
2
3
4
5
6
7
8
9
10
RESEARCH PAPERS – 2016
Burden of Comorbidity in Systemic Lupus Erythematosus in the UK, 1999-2012.
Rees F, Doherty M, Grainge M, Lanyon P, Davenport G, Zhang W.
Arthritis care & research 2016 06;68(6):819-27.
Blood Pressure and Risk of Vascular Dementia: Evidence From a Primary Care Registry and a
Cohort Study of Transient Ischemic Attack and Stroke.
Emdin CA, Rothwell PM, Salimi-Khorshidi G, Kiran A, Conrad N, Callender T, Mehta Z,
Pendlebury ST, Anderson SG, Mohseni H, Woodward M, Rahimi K.
Stroke 2016 06;47(6):1429-35.
Epidemiology of poisonings, fractures and burns among 0-24 year olds in England using linked health and mortality data.
Baker R, Orton E, Tata LJ, Kendrick D.
Eur J Public Health 2016 May 31.
Maternal Pre-pregnancy Body Mass Index and Autism Spectrum Disorder among Offspring: A
Population-Based Case-Control Study.
Getz KD, Anderka MT, Werler MM, Jick SS.
Paediatr Perinat Epidemiol 2016 May 30.
Comorbidity Burden in Trial-Aligned Patients with Established Gout in Germany, UK, US, and
France: a Retrospective Analysis.
Nyberg F, Horne L, Morlock R, Nuevo J, Storgard C, Aiyer L, Hines DM, Ansolabehere X,
Chevalier P.
Adv Ther 2016 May 26.
Associations of antibiotic use with risk of primary liver cancer in the Clinical Practice Research
Datalink.
Yang B, Hagberg KW, Chen J, Sahasrabuddhe VV, Graubard BI, Jick S, McGlynn KA.
Br J Cancer 2016 May 24.
A methodological comparison of two European primary care databases and replication in a US claims database: inhaled long-acting beta-2-agonists and the risk of acute myocardial infarction.
Afonso A, Schmiedl S, Becker C, Tcherny-Lessenot S, Primatesta P, Plana E, Souverein P,
Wang Y, Korevaar JC, Hasford J, Reynolds R, de Groot MCH, Schlienger R, Klungel O,
Rottenkolber M.
Eur J Clin Pharmacol 2016 May 24.
The association between benzodiazepines and influenza-like illness-related pneumonia and mortality: a survival analysis using UK Primary Care data.
Nakafero G, Sanders RD, Nguyen-Van-Tam JS, Myles PR.
Pharmacoepidemiol Drug Saf 2016 May 23.
Microvascular disease and risk of cardiovascular events among individuals with type 2 diabetes: a population-level cohort study.
Brownrigg JRW, Hughes CO, Burleigh D, Karthikesalingam A, Patterson BO, Holt PJ, Thompson
MM, de Lusignan S, Ray KK, Hinchliffe RJ.
The lancet.Diabetes & endocrinology 2016 May 20.
Risk of solid organ transplant rejection following vaccination with seasonal trivalent inactivated influenza vaccines in England: A self-controlled case-series.
Dos Santos G, Haguinet F, Cohet C, Webb D, Logie J, Ferreira GLC, Rosillon D, Shinde V.

11
12
13
14
15
16
17
18
19
20
21
22
Vaccine 2016 May 20.
Identification of impaired fasting glucose, healthcare utilization and progression to diabetes in the UK using the Clinical Practice Research Datalink (CPRD).
Hong J, McNeill AM, He J, Chen Y, Brodovicz KG.
Pharmacoepidemiol Drug Saf 2016 May 19.
Is omission of free text records a possible source of data loss and bias in Clinical Practice
Research Datalink studies? A case-control study.
Price SJ, Stapley SA, Shephard E, Barraclough K, Hamilton WT.
BMJ open 2016 May 13;6(5):e011664.
Comparative risk of major cardiovascular events associated with second-line antidiabetic treatments: a retrospective cohort study using UK primary care data linked to hospitalisation and mortality records.
Zghebi SS, Steinke DT, Rutter MK, Emsley RA, Ashcroft DM.
Diabetes Obes Metab 2016 May 13.
Regression Coefficient Based Scoring System Should be Used to Assign Weights to the Risk
Index.
Mehta HB, Mehta V, Girman CJ, Adhikari D, Johnson ML.
J Clin Epidemiol 2016 May 12.
Respiratory effect of beta-blocker eye drops in asthma: population based study and metaanalysis of clinical trials.
Morales DR, Dreischulte T, Lipworth BJ, Donnan PT, Jackson C, Guthrie B.
Br J Clin Pharmacol 2016 May 10.
Phosphodiesterase Type 5 Inhibitors and the Risk of Melanoma Skin Cancer.
Lian Y, Yin H, Pollak MN, Carrier S, Platt RW, Suissa S, Azoulay L.
Eur Urol 2016 May 10.
Insulin glargine use and breast cancer risk: Associations with cumulative exposure.
Peeters PJHL, Bazelier MT, Leufkens HGM, Auvinen A, van Staa T,P., de Vries F, De Bruin ML.
Acta Oncol 2016 May 06:1-8.
Excess Costs Associated with Possible Misdiagnosis of Alzheimer's Disease Among Patients with Vascular Dementia in a UK CPRD Population.
Happich M, Kirson NY, Desai U, King S, Birnbaum HG, Reed C, Belger M, Lenox-Smith A, Price
D.
Journal of Alzheimer's disease : JAD 2016 May 06.
Association between Insulin Monotherapy versus Insulin plus Metformin and the Risk of All-
Cause Mortality and Other Serious Outcomes: A Retrospective Cohort Study.
Holden SE, Jenkins-Jones S, Currie CJ.
PloS one 2016 May 06;11(5):e0153594.
The risk of community-acquired pneumonia among 9803 patients with coeliac disease compared to the general population: a cohort study.
Zingone F, Abdul Sultan A, Crooks CJ, Tata LJ, Ciacci C, West J.
Aliment Pharmacol Ther 2016 May 05.
Prescribing Trends of Attention-Deficit Hyperactivity Disorder (ADHD) Medications in UK
Primary Care, 1995-2015.
Renoux C, Shin J, Dell'Aniello S, Fergusson E, Suissa S.
Br J Clin Pharmacol 2016 May 04.
Lifestyle factors, psychiatric and neurologic comorbidities, and drug use associated with incident seizures among adult patients with depression: a population-based nested casecontrol study.
Bloechliger M, Ceschi A, Rüegg S, Jick SS, Meier CR, Bodmer M.
Eur J Epidemiol 2016 May 04.

23
24
25
26
27
28
29
30
31
32
33
34
Digoxin use after diagnosis of prostate cancer and survival: a population-based cohort study.
Karasneh RA, Murray LJ, Hughes CM, Cardwell CR.
Pharmacoepidemiol Drug Saf 2016 May 04.
Safety and Effectiveness of Statins for Prevention of Recurrent Myocardial Infarction in 12 156
Typical Older Patients: A Quasi-Experimental Study.
Ble A, Hughes PM, Delgado J, Masoli JA, Bowman K, Zirk-Sadowski J, Mujica Mota RE, Henley
WE, Melzer D.
The journals of gerontology.Series A, Biological sciences and medical sciences 2016 May 04.
Severity of Diabetes Mellitus and Total Hip or Knee Replacement: A Population-Based Case-
Control Study.
Nielen JTH, Emans PJ, Dagnelie PC, Boonen A, Lalmohamed A, de Boer A, van den Bemt BJF, de Vries F.
Medicine 2016 05;95(20):e3739.
Using electronic health records to predict costs and outcomes in stable coronary artery disease.
Asaria M, Walker S, Palmer S, Gale CP, Shah AD, Abrams KR, Crowther M, Manca A, Timmis
A, Hemingway H, Sculpher M.
Heart 2016 May 15;102(10):755-62.
Impact of the National Health Service Health Check on cardiovascular disease risk: a difference-in-differences matching analysis.
Chang KC, Lee JT, Vamos EP, Soljak M, Johnston D, Khunti K, Majeed A, Millett C.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
2016 May 02.
Association of smoking and concomitant metformin use with cardiovascular events and mortality in people newly diagnosed with type 2 diabetes.
Paul SK, Klein K, Majeed A, Khunti K.
Journal of Diabetes 2016 May 01;8(3):354-362.
Are healthcare costs from obesity associated with body mass index, comorbidity or depression? Cohort study using electronic health records.
Rudisill C, Charlton J, Booth HP, Gulliford MC.
Clinical Obesity 2016 Jun 01;6(3):225-231. [Epub released May 16]
Influenza and Pneumococcal Vaccination Uptake in Patients with Rheumatoid Arthritis Treated with Immunosuppressive Therapy in the UK: A Retrospective Cohort Study Using Data from the Clinical Practice Research Datalink.
Costello R, Winthrop KL, Pye SR, Brown B, Dixon WG.
PloS one 2016 Apr 20;11(4):e0153848.
COPD disease severity and the risk of venous thromboembolic events: A matched case-control study.
Morgan AD, Herrett E, De Stavola BL, Smeeth L, Quint JK.
International Journal of COPD 2016 Apr 28;11(1):899-908.
Evaluation of the risk of cardiovascular events with clarithromycin using both propensity score and self-controlled study designs.
Root AA, Wong AYS, Ghebremichael-Weldeselassie Y, Smeeth L, Bhaskaran K, Evans SJW,
Brauer R, Wong ICK, Navaratnam V, Douglas I.
Br J Clin Pharmacol 2016 Apr 19.
A UK general practice population cohort study investigating the association between lipid lowering drugs and 30-day mortality following medically attended acute respiratory illness.
Joshi R, Venkatesan S, Myles PR.
PeerJ 2016 Apr 18;4:e1902.
Understanding flucloxacillin prescribing trends and treatment non-response in UK primary care: a Clinical Practice Research Datalink (CPRD) study.
Francis NA, Hood K, Lyons R, Butler CC.

35
36
37
38
39
40
41
42
43
44
45
46
47
J Antimicrob Chemother 2016 Apr 18.
Risk of recurrent venous thromboembolism after discontinuation of vitamin K antagonist treatment: a nested case-control study.
Martinez C, Katholing A, Folkerts K, Cohen AT.
Journal of thrombosis and haemostasis : JTH 2016 Apr 15.
Which Patients with Giant Cell Arteritis Will Develop Cardiovascular or Cerebrovascular
Disease? A Clinical Practice Research Datalink Study.
Robson JC, Kiran A, Maskell J, Hutchings A, Arden N, Dasgupta B, Hamilton W, Emin A,
Culliford D, Luqmani R.
J Rheumatol 2016 Apr 15.
Clobazam and clonazepam use in epilepsy: Results from a UK database incident user cohort study.
Brodie MJ, Chung S, Wade A, Quelen C, Guiraud-Diawara A, François C, Verpillat P, Shen V,
Isojarvi J.
Epilepsy Res 2016 Apr 11;123:68-74.
Ventricular tachyarrhythmia and sudden cardiac death with domperidone use in Parkinson's
Disease.
Renoux C, Dell'Aniello S, Khairy P, Marras C, Bugden S, Turin TC, Blais L, Tamim H, Evans C,
Steele R, Dormuth C, Ernst P.
Br J Clin Pharmacol 2016 Apr 07.
A population-based study examining the risk of malignancy in patients diagnosed with inflammatory bowel disease.
Wilson JC, Furlano RI, Jick SS, Meier CR.
J Gastroenterol 2016 Apr 07.
Association between oral fluoroquinolones and seizures: A self-controlled case series study.
Chui CSL, Chan EW, Wong AYS, Root A, Douglas IJ, Wong ICK.
Neurology 2016 May 03;86(18):1708-15. [Epub released Apr 16]
Intrauterine device use and the risk of pre-eclampsia: A case-control study.
Parker SE, Jick SS, Werler MM.
BJOG: An International Journal of Obstetrics and Gynaecology 2016 Apr 01;123(5):788-795.
COPD exacerbations by disease severity in England.
Merinopoulou E, Raluy-Callado M, Ramagopalan S, Maclachlan S, Khalid JM.
International Journal of COPD 2016 Apr 01;11(1):697-709.
Clinical workload in UK primary care: a retrospective analysis of 100 million consultations in
England, 2007–14
Hobbs FDR, Bankhead C, Mukhtar T, Stevens S, Perera-Salazar R, Holt T, Salisbury C
The Lancet doi:10.1016/S0140-6736(16)00620-6
Clinical inertia with regard to intensifying therapy in people with type 2 diabetes treated with basal insulin.
Khunti K, Nikolajsen A, Thorsted BL, Andersen M, Davies MJ, Paul SK.
Diabetes Obes Metab 2016 04;18(4):401-9.
Metformin use and survival from lung cancer: A population-based cohort study.
Menamin ÚCM, Cardwell CR, Hughes CM, Murray LM.
Lung Cancer 2016 Apr 01;94:35-39.
Instrumental variable analysis as a complementary analysis in studies of adverse effects:
Venous thromboembolism and second-generation versus third-generation oral contraceptives.
Boef AGC, Souverein PC, Vandenbroucke JP, van HV, de Boer A, le Cessie S, Dekkers OM.
Pharmacoepidemiol Drug Saf 2016 Mar 01;25(3):317-324.
Use of calcium channel blockers and risk of breast cancer: a population-based cohort study.
Azoulay L, Soldera S, Yin H, Bouganim N.

48
49
50
51
52
53
54
55
56
57
58
59
Epidemiology 2016 Mar 30.
Targeted Maximum Likelihood Estimation for Pharmacoepidemiological Research.
Pang M, Schuster T, Filion KB, Eberg M, Platt RW.
Epidemiology 2016 Mar 29.
A multicenter observational study of incretin-based drugs and heart failure.
Filion KB, Azoulay L, Platt RW, Dahl M, Dormuth CR, Clemens KK, Hu N, Paterson JM,
Targownik L, Turin TC, Udell JA, Ernst P, Ma Z, Zhang J, Carney GA, Coulombe J, Yin H, Wu
CF, Hollands S, Jin S, Mizrahi C, Dahan M, Sang L, Pang M, Durand M, Cardinal H, Suissa K.
N Engl J Med 2016 Mar 24;374(12):1145-1154.
Impact of varying outcomes and definitions of suicidality on the associations of antiepileptic drugs and suicidality: comparisons from UK Clinical Practice Research Datalink (CPRD) and
Danish national registries (DNR).
Schuerch M, Gasse C, Robinson NJ, Alvarez Y, Walls R, Mors O, Christensen J, Hesse U, de
Groot M, Schlienger R, Reynolds R, Klungel O, de Vries F.
Pharmacoepidemiol Drug Saf 2016 03;25 Suppl 1:142-155.
Pioglitazone use and risk of bladder cancer: population based cohort study.
Tuccori M, Filion KB, Yin H, Yu OH, Platt RW, Azoulay L.
BMJ 2016 Mar 30;352:i1541.
Dental consultations in UK general practice and antibiotic prescribing rates: a retrospective cohort study.
Cope AL, Chestnutt IG, Wood F, Francis NA.
The British journal of general practice : the journal of the Royal College of General
Practitioners 2016 05;66(646):e329-36. [Epub released Mar 2016]
Population prevalence of Down's syndrome in the United Kingdom.
Alexander M, Ding Y, Foskett N, Petri H, Wandel C, Khwaja O.
Journal of intellectual disability research : JIDR 2016 Mar 28.
Influenza infections and risk of Alzheimer's disease.
Imfeld P, Toovey S, Jick SS, Meier CR.
Brain Behav Immun 2016 Mar 19.
Smoking-related mortality in patients with early rheumatoid arthritis - a retrospective cohort study using the Clinical Practice Research Datalink.
Joseph RM, Movahedi M, Dixon WG, Symmons DPM.
Arthritis care & research 2016 Mar 18.
Trends in long-term opioid prescribing in primary care patients with musculoskeletal conditions: an observational database study.
Bedson J, Chen Y, Ashworth J, Hayward RA, Walters K, Dunn KM, Jordan KP.
Pain 2016 Mar 18.
High Dose Atorvastatin Associated with Increased Risk of Significant Hepatotoxicity in
Comparison to Simvastatin in UK GPRD Cohort.
Clarke AT, Johnson PCD, Hall GC, Ford I, Mills PR.
PloS one 2016 Mar 16;11(3):e0151587.
Prostate-specific antigen testing rates and referral patterns from general practice data in
England.
Moss S, Melia J, Sutton J, Mathews C, Kirby M.
Int J Clin Pract 2016 Apr 01;70(4):312-318. [Epub released Mar 2016]
Metabolic syndrome in relation to Barrett's esophagus and esophageal adenocarcinoma:
Results from a large population-based case-control study in the Clinical Practice Research
Datalink.
Drahos J, Li L, Jick SS, Cook MB.
Cancer Epidemiology 2016 Jun 01;42:9-14. [Epub released Mar 2016]

60
61
62
63
64
65
66
67
68
69
70
71
Epidemiology of fractures in the United Kingdom 1988-2012: Variation with age, sex, geography, ethnicity and socioeconomic status.
Curtis EM, van dV, Moon RJ, van den Bergh J,P.W., Geusens P, de Vries F, van Staa TP,
Cooper C, Harvey NC.
Bone 2016 Jun 01;87:19-26. [Epub released Mar 2016]
Predicting the 10-year risk of hip and major osteoporotic fracture in rheumatoid arthritis and in the general population: an independent validation and update of UK FRAX without bone mineral density.
Klop C, de Vries F, Bijlsma JWJ, Leufkens HGM, Welsing PMJ.
Ann Rheum Dis 2016 Mar 16.
High risk of drug-induced microscopic colitis with concomitant use of NSAIDs and proton pump inhibitors
Verhaegh BPM, de Vries F, Masclee AAM, Keshavarzian A, de Boer A, Souverein PC,
Pierik MJ, Jonkers DMAE.
Aliment Pharmacol Ther 2016 05;43(9):1004-13. [Epub released Mar 2016]
Validation of the Recording of Acute Exacerbations of COPD in UK Primary Care Electronic
Healthcare Records.
Rothnie KJ, Müllerová H, Hurst JR, Smeeth L, Davis K, Thomas SL, Quint JK.
PloS one 2016 Mar 09;11(3):e0151357.
Clinical management following self-harm in a UK-wide primary care cohort.
Carr MJ, Ashcroft DM, Kontopantelis E, While D, Awenat Y, Cooper J, Chew-Graham C, Kapur
N, Webb RT.
J Affect Disord 2016 06;197:182-188. [Epub released Mar 2016]
Metformin and the risk of renal cell carcinoma: a case-control analysis.
Becker C, Jick SS, Meier CR, Bodmer M.
European journal of cancer prevention : the official journal of the European Cancer Prevention
Organisation (ECP) 2016 Mar 03.
Diabetes, use of antidiabetic drugs, and the risk of glioma.
Seliger C, Ricci C, Meier CR, Bodmer M, Jick SS, Bogdahn U, Hau P, Leitzmann MF.
Neuro-oncology 2016 03;18(3):340-9.
Symptoms of adult chronic and acute leukaemia before diagnosis: large primary care casecontrol studies using electronic records.
Shephard EA, Neal RD, Rose PW, Walter FM, Hamilton W.
The British journal of general practice : the journal of the Royal College of General
Practitioners 2016 03;66(644):e182-8.
Performance characteristics of visualising the cervix in symptomatic young females: a review of primary care records in females with and without cervical cancer.
Lim AWW, Hamilton W, Hollingworth A, Stapley S, Sasieni P.
The British journal of general practice : the journal of the Royal College of General
Practitioners 2016 03;66(644):e189-92.
The epidemiology of self-harm in a UK-wide primary care patient cohort, 2001-2013.
Carr MJ, Ashcroft DM, Kontopantelis E, Awenat Y, Cooper J, Chew-Graham C, Kapur N, Webb
RT.
BMC Psychiatry 2016 Feb 29;16(1):53.
Effect of Contemporary Bariatric Surgical Procedures on Type 2 Diabetes Remission. A
Population-Based Matched Cohort Study.
Gulliford MC, Booth HP, Reddy M, Charlton J, Fildes A, Prevost AT, Khan O.
Obesity Surg 2016 Feb 27.
Modelling Conditions and Health Care Processes in Electronic Health Records: An Application to Severe Mental Illness with the Clinical Practice Research Datalink.
Olier I, Springate DA, Ashcroft DM, Doran T, Reeves D, Planner C, Reilly S, Kontopantelis E.
PloS one 2016 Feb 26;11(2):e0146715.

72
73
74
75
76
77
78
79
80
81
82
83
84
Consequences of delaying treatment intensification in type 2 diabetes: evidence from a UK database.
Watson L, Das R, Farquhar R, Langerman H, Barnett AH.
Curr Med Res Opin 2016 Feb 24:1-39.
Incidence of adult Huntington's disease in the UK: a UK-based primary care study and a systematic review.
Wexler NS, Collett L, Wexler AR, Rawlins MD, Tabrizi SJ, Douglas I, Smeeth L, Evans SJ.
BMJ open 2016 Feb 23;6(2):e009070.
Comparative estimated effectiveness of antibiotic classes as initial and secondary treatments of respiratory tract infections: longitudinal analysis of routine data from UK primary care
1991-2012.
Berni E, Butler CC, Jenkins-Jones S, de Voogd H, Ouwens M, Morgan CL, Currie CJ.
Curr Med Res Opin 2016 06;32(6):1023-32. [Epub released Feb 16]
Incidence rates of suicidal behaviors and treated depression in patients with and without psoriatic arthritis using the Clinical Practice Research Datalink.
Hagberg KW, Li L, Peng M, Shah K, Paris M, Jick S.
Modern rheumatology / the Japan Rheumatism Association 2016 Feb 16:1-6.
Rates of Cancers and Opportunistic Infections in Patients with Psoriatic Arthritis Compared
With Patients Without Psoriatic Arthritis.
Hagberg KW, Li L, Peng M, Paris M, Shah K, Jick SS.
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases
2016 Feb 13.
Use of Selective Cyclooxygenase-2 Inhibitors, Other Analgesics, and Risk of Glioma.
Seliger C, Meier CR, Becker C, Jick SS, Bogdahn U, Hau P, Leitzmann, MF.
PloS one 2016 Feb 12;11(2):e0149293.
Modelling and extraction of variability in free-text medication prescriptions from an anonymised primary care electronic medical record research database.
Karystianis G, Sheppard T, Dixon WG, Nenadic G.
BMC medical informatics and decision making 2016 Feb 09;16(1):18.
The Impact of the Choice of Data Source in Record Linkage Studies Estimating Mortality in
Venous Thromboembolism.
Gallagher AM, Williams T, Leufkens HGM, de Vries F.
PloS one 2016 Feb 10;11(2):e0148349.
Contemporary reproductive outcomes for patients with polycystic ovary syndrome: a retrospective observational study.
Rees DA, Jenkins-Jones S, Morgan CL.
J Clin Endocrinol Metab 2016 Feb 09:jc20152682.
No association between exacerbation frequency and stroke in patients with COPD.
Windsor C, Herrett E, Smeeth L, Quint JK.
International Journal of COPD 2016 Feb 02;11:217-225.
Does Angiotensin-Converting Enzyme Inhibitor and β-Blocker Use Reduce the Risk of Primary
Liver Cancer? A Case-Control Study Using the UK Clinical Practice Research Datalink.
Hagberg KW, Sahasrabuddhe VV, McGlynn KA, Jick SS.
Pharmacotherapy 2016 02;36(2):187-95.
Influenza-attributable burden in United Kingdom primary care.
Fleming DM, Taylor RJ, Haguinet F, Schuck-Paim C, Logie J, Webb DJ, Lustig RL, Matias G.
Epidemiol Infect 2016 02;144(3):537-47.
Effect of the adjuvanted (AS03) A/H1N1 2009 pandemic influenza vaccine on the risk of rejection in solid organ transplant recipients in England: a self-controlled case series.

85
86
87
88
89
90
91
92
93
94
95
96
Cohet C, Haguinet F, Dos Santos G, Webb D, Logie J, Lc Ferreira G, Rosillon D, Shinde V.
BMJ open 2016 Jan 28;6(1):e009264.
Risk of symptomatic venous thromboembolism following emergency appendicectomy in adults.
Humes DJ, Walker AJ, Hunt BJ, Sultan AA, Ludvigsson JF, West J.
Br J Surg 2016 03;103(4):443-50. [Epub released Mar 2016]
Ethnic and geographic variations in the epidemiology of childhood fractures in the United
Kingdom.
Moon RJ, Harvey NC, Curtis EM, de Vries F, van Staa T, Cooper C.
Bone 2016 Apr 01;85:9-14. [Epub released Jan 2016]
Diagnosis of acute kidney injury and its association with in-hospital mortality in patients with infective exacerbations of bronchiectasis: Cohort study from a UK nationwide database.
Iwagami M, Mansfield K, Quint J, Nitsch D, Tomlinson L.
BMC Pulmonary Medicine 2016 Jan 19;16(1).
Asthma medication prescribing before, during and after pregnancy: a study in seven European regions.
Charlton RA, Pierini A, Klungsøyr K, Neville AJ, Jordan S, de Jong-van den Berg, Lolkje TW,
Thayer D, Bos HJ, Puccini A, Hansen AV, Gini R, Engeland A, Nybo Andersen A, Dolk H, Garne
E.
BMJ open 2016 Jan 19;6(1):e009237.
Changing Epidemiology of Bariatric Surgery in the UK: Cohort Study Using Primary Care
Electronic Health Records.
Booth HP, Khan O, Fildes A, Prevost AT, Reddy M, Charlton J, Gulliford MC.
Obesity Surg 2016 Jan 12:1-6.
Calcium channel blockers and cancer: a risk analysis using the UK Clinical Practice Research
Datalink (CPRD).
Grimaldi-Bensouda L, Klungel O, Kurz X, de Groot MC., Maciel Afonso AS, de Bruin ML,
Reynolds R, Rossignol M.
BMJ open 2016 Jan 08;6(1):e009147.
Association Between Statin Use After Diagnosis of Esophageal Cancer and Survival: a
Population-based Cohort Study.
Alexandre L, Clark AB, Bhutta HY, Chan SSM, Lewis MPN, Hart AR.
Gastroenterology 2016 04;150(4):854-865.e1. [Epub released Jan 2016]
Improved incidence estimates from linked versus stand-alone electronic health records.
Millett ERC, Quint JK, De Stavola B,L., Smeeth L, Thomas SL.
J Clin Epidemiol 2016 Jan 08.
Mortality in systemic lupus erythematosus in the United Kingdom 1999-2012.
Rees F, Doherty M, Grainge MJ, Lanyon P, Davenport G, Zhang W.
Rheumatology (Oxford) 2016 05;55(5):854-60. [Epub released Jan 2016]
Clinical inertia in intensifying therapy among people with type 2 diabetes treated with basal insulin.
Khunti K, Nikolajsen A, Thorsted BL, Andersen M, Davies MJ, Paul SK.
Diabetes Obes Metab 2016 Jan 07.
Predicting frequent asthma exacerbations using blood eosinophil count and other patient data routinely available in clinical practice.
Price D, Wilson AM, Chisholm A, Rigazio A, Burden A, Thomas M, King C.
Journal of asthma and allergy 2016 Jan 07;9:1-12.
Rates and predictors of progression to esophageal carcinoma in a large population-based
Barrett's esophagus cohort.
Krishnamoorthi R, Borah B, Heien H, Das A, Chak A, Iyer PG.
Gastrointest Endosc 2016 Jan 06.

97
98
Molluscum contagiosum and associations with atopic eczema in children: a retrospective longitudinal study in primary care.
Olsen JR, Piguet V, Gallacher J, Francis NA.
The British journal of general practice : the journal of the Royal College of General
Practitioners 2016 01;66(642):e53-8.
Severity of obesity and management of hypertension, hypercholesterolaemia and smoking in primary care: population-based cohort study.
Booth HP, Prevost AT, Gulliford MC.
J Hum Hypertens 2016 01;30(1):40-5.
1
2
3
4
5
6
7
8
9
Use of cardiac glycosides and risk of glioma.
Seliger C, Meier CR, Jick SS, Uhl M, Bogdahn U, Hau P, Leitzmann MF.
J Neurooncol 2016 04;127(2):321-8. [Epub released Dec 2015]
Rosacea in Patients with Ulcerative Colitis and Crohn's Disease: A Population-based Casecontrol Study.
Spoendlin J, Karatas G, Furlano RI, Jick SS, Meier CR.
Inflamm Bowel Dis 2016 03;22(3):680-7. [Epub released Dec 2015]
Risk of Post-Discharge Venous Thromboembolism and Associated Mortality in General
Surgery: A Population-Based Cohort Study Using Linked Hospital and Primary Care Data in
England.
Bouras G, Burns EM, Howell A, Bottle A, Athanasiou T, Darzi A.
PloS one 2015 Dec 29;10(12):e0145759.
Half of UK patients with rheumatoid arthritis are prescribed oral glucocorticoid therapy in primary care: a retrospective drug utilisation study.
Black RJ, Joseph RM, Brown B, Movahedi M, Lunt M, Dixon WG.
Arthritis research & therapy 2015 Dec 24;17(1):375.
An algorithm to identify rheumatoid arthritis in primary care: a Clinical Practice Research
Datalink study.
Muller S, Hider SL, Raza K, Stack RJ, Hayward RA, Mallen CD.
BMJ open 2015 Dec 23;5(12):e009309.
Non-Persistence and Non-Adherence of Patients with Type 2 Diabetes Mellitus in Therapy with
GLP-1 Receptor Agonists: A Retrospective Analysis.
Wilke T, Mueller S, Groth A, Berg B, Fuchs A, Sikirica M, Logie J, Martin A, Maywald U.
Diabetes therapy : research, treatment and education of diabetes and related disorders 2016
03;7(1):105-24. [Epub released Dec 2015]
Bariatric Surgery in the United Kingdom: A Cohort Study of Weight Loss and Clinical
Outcomes in Routine Clinical Care.
Douglas IJ, Bhaskaran K, Batterham RL, Smeeth L.
PLoS medicine 2015 Dec 22;12(12):e1001925.
Adherence to Oral Glucose-Lowering Therapies and Associations With 1-Year HbA1c: A
Retrospective Cohort Analysis in a Large Primary Care Database.
Farmer AJ, Rodgers LR, Lonergan M, Shields B, Weedon MN, Donnelly L, Holman RR, Pearson
ER, Hattersley AT .
Diabetes Care 2016 02;39(2):258-63. [Epub released Dec 15]
Impact of gout on the risk of atrial fibrillation.
Kuo C, Grainge MJ, Mallen C, Zhang W, Doherty M.

10
11
12
13
14
15
16
17
18
19
20
Rheumatology (Oxford) 2016 04;55(4):721-8. [Epub released Dec 2015]
Primary care consultation rates among people with and without severe mental illness: a UK cohort study using the Clinical Practice Research Datalink.
Kontopantelis E, Olier I, Planner C, Reeves D, Ashcroft DM, Gask L, Doran T, Reilly S.
BMJ open 2015 Dec 16;5(12):e008650.
Inequalities in physical comorbidity: a longitudinal comparative cohort study of people with severe mental illness in the UK.
Reilly S, Olier I, Planner C, Doran T, Reeves D, Ashcroft DM, Gask L, Kontopantelis E.
BMJ open 2015 Dec 15;5(12):e009010.
Risk of Incident Diabetes Mellitus Associated With the Dosage and Duration of Oral
Glucocorticoid Therapy in Patients With Rheumatoid Arthritis
Movahedi M, Beauchamp M, Abrahamowicz M, Ray DW, Michaud K, Pedro S, Dixon WG.
Arthritis & rheumatology (Hoboken, N.J.) 2016 05;68(5):1089-98. [Epub released Dec 2015]
Menopausal hormone therapy use and risk of primary liver cancer in the Clinical Practice
Research Datalink.
McGlynn KA, Hagberg K, Chen J, Braunlin M, Graubard BI, Sunaya N, Jick S, Sahasrabuddhe
VV.
International journal of cancer.Journal international du cancer 2016 May 01;138(9):2146-53.
[Epub released Dec 2015]
The clinical profile of tuberous sclerosis complex (TSC) in the United Kingdom: A retrospective cohort study in the Clinical Practice Research Datalink (CPRD).
Kingswood C, Bolton P, Crawford P, Harland C, Johnson SR, Sampson JR, Shepherd C, Spink
J, Demuth D, Lucchese L, Nasuti P, Gray E, Pinnegar A, Magestro M.
European journal of paediatric neurology : EJPN : official journal of the European Paediatric
Neurology Society 2016 03;20(2):296-308. [Epub released Dec 2015]
Risk of Seizures Associated with Antidepressant Use in Patients with Depressive Disorder:
Follow-up Study with a Nested Case-Control Analysis Using the Clinical Practice Research
Datalink.
Bloechliger M, Ceschi A, Rüegg S, Kupferschmidt H, Kraehenbuehl S, Jick SS, Meier CR,
Bodmer M.
Drug safety 2016 04;39(4):307-21 [Epub released Dec 2015]
Occurrence and Recurrence of Attempted Suicide Among People With Epilepsy.
Hesdorffer DC, Ishihara L, Webb DJ, Mynepalli L, Galwey NW, Allen Hauser W.
JAMA Psychiatry 2016 01;73(1):80-86. [Epub released Dec 2015]
The risk of new onset depression in association with influenza - a population-based observational study.
Bornand D, Toovey S, Jick SS, Meier CR.
Brain Behav Immun 2016 03;53:131-7. [Epub released Dec 2015]
Adrenergic blockers and the risk for common solid cancers: a case-control study.
Numbere B, Fleming KM, Walker A, Card TR.
European journal of cancer prevention : the official journal of the European Cancer Prevention
Organisation (ECP) 2015 Dec 08.
Optimal strategies for monitoring lipid levels in patients at risk or with cardiovascular disease: a systematic review with statistical and cost-effectiveness modelling.
Perera R, McFadden E, McLellan J, Lung T, Clarke P, Pérez T, Fanshawe T, Dalton A, Farmer A,
Glasziou P, Takahashi O, Stevens J, Irwig L, Hirst J, Stevens S, Leslie A, Ohde S, Deshpande
G, Urayama K, Shine B, Stevens R.
Health Technol Assess 2015 12;19(100):1-402.
Association of hormone therapy and incident gout: population-based case-control study.
Bruderer SG, Bodmer M, Jick SS, Meier CR.
Menopause 2015 12;22(12):1335-42.

21
22
23
24
25
26
27
28
29
30
31
Risk of vertebral and non-vertebral fractures in patients with sarcoidosis: a population-based cohort.
Bours S, de Vries F, van den Bergh JPW, Lalmohamed A, van Staa TP, Leufkens HGM,
Geusens PPP, Drent M, Harvey NC.
Osteoporosis international : a journal established as result of cooperation between the
European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
2016 04;27(4):1603-10. [Epub released Dec 2015]
Risk factors for hospital admission in the 28 days following a community-acquired pneumonia diagnosis in older adults, and their contribution to increasing hospitalisation rates over time: a cohort study.
Millett ERC, De Stavola B,L., Quint JK, Smeeth L, Thomas SL.
BMJ open 2015 Dec 01;5(12):e008737.
Associations between exemption and survival outcomes in the UK's primary care pay-forperformance programme: a retrospective cohort study.
Kontopantelis E, Springate DA, Ashcroft DM, Valderas JM, van der Veer S,N., Reeves D,
Guthrie B, Doran T.
BMJ quality & safety 2015 Dec 01.
Identification of antithrombotic drugs related to total joint replacement using anonymised free-text notes: a search strategy in the Clinical Practice Research Datalink
Nielen JTH, van den Bemt BJF, Boonen A, Dagnelie PC, Emans PJ, Veldhorst N, Lalmohamed
A, van Staa TP, de Vries F.
BMJ Open 2015;5:11 e009017 doi:10.1136/bmjopen-2015-009017
Pattern of symptoms and signs of primary intracranial tumours in children and young adults: a record linkage study.
Chu TPC, Shah A, Walker D, Coleman MP.
Arch Dis Child 2015 12;100(12):1115-22.
Comorbidities, bone-sparing agent prescription history and their determinants among postmenopausal women in UK primary care settings: a retrospective database study.
Feudjo-Tepie M, Ferguson S, Roddam A, Taylor A, Bayly J, Critchlow C.
Archives of Osteoporosis 2015 Dec 01;10(1):1-11.
Risk of Out-of-Hospital Sudden Cardiac Death in Users of Domperidone, Proton Pump
Inhibitors, or Metoclopramide: A Population-Based Nested Case-Control Study.
Arana A, Johannes CB, McQuay LJ, Varas-Lorenzo C, Fife D, Rothman KJ.
Drug safety 2015 12;38(12):1187-99.
Rates of Cardiovascular Disease and Major Adverse Cardiovascular Events in Patients With
Psoriatic Arthritis Compared to Patients Without Psoriatic Arthritis.
Li L, Hagberg KW, Peng M, Shah K, Paris M, Jick S.
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases
2015 12;21(8):405-10.
Incidence and mortality of relapsing polychondritis in the UK: a population-based cohort study.
Hazra N, Dregan A, Charlton J, Gulliford MC, D'Cruz D,P.
Rheumatology (Oxford) 2015 12;54(12):2181-7.
Linked Hospital and Primary Care Database Analysis of the Incidence and Impact of
Psychiatric Morbidity Following Gastrointestinal Cancer Surgery in England.
Bouras G, Markar SR, Burns EM, Mackenzie HA, Bottle A, Athanasiou T, Hanna GB, Darzi A.
Ann Surg 2015 Nov 26.
Weight change and healthcare resource use in English patients with type 2 diabetes mellitus initiating a new diabetes medication class.
Blak BT, Rigney U, Sternhufvud C, Davis J, Hammar N.
Int J Clin Pract 2016 01;70(1):45-55. [Epub released Nov 2015]

32
33
34
35
36
37
38
39
40
41
42
43
ADHD in the United Kingdom: Regional and Socioeconomic Variations in Incidence Rates
Amongst Children and Adolescents (2004-2013).
Hire AJ, Ashcroft DM, Springate DA, Steinke DT.
Journal of attention disorders 2015 Nov 23.
Use of Incretin Agents and Risk of Pancreatic Cancer: A Population-Based Cohort Study.
Knapen LM, van Dalem J, Keulemans YC, van Erp NP, Bazelier MT, De Bruin ML, Leufkens HG,
Croes S, Neef C, de Vries F, Driessen JH
Diabetes Obes Metab 2016 03;18(3):258-65. [Epub released Nov 2015]
Chronic renal disease is not chronic kidney disease: implications for use of the QRISK and
Joint British Societies risk scores.
Stevens SL, Stevens RJ, Hobbs FR, Lasserson DS.
Fam Pract 2016 02;33(1):57-60. [Epub released Nov 2015]
Low-dose aspirin and survival from lung cancer: a population-based cohort study.
Mc Menamin Ú,C., Cardwell CR, Hughes CM, Murray LM.
BMC Cancer 2015 Nov 17;15(1):911.
History of cardiovascular events and cardiovascular risk factors among patients initiating strontium ranelate for treatment of osteoporosis.
Yu J, Tang J, Li Z, Sajjan S, O'Regan C, Modi A, Sazonov V.
International journal of women's health 2015 Nov 17;7:913-918.
When are breast cancer patients at highest risk of venous thromboembolism: a cohort study using English healthcare data.
Walker AJ, West J, Card TR, Crooks C, Kirwan CC, Grainge MJ.
Blood 2016 Feb 18;127(7):849-57. [Epub released Nov 2015]
Characteristics, disease burden and costs of COPD patients in the two years following initiation of long-acting bronchodilators in UK primary care.
Punekar YS, Landis SH, Wurst K, Le H.
Respiratory research 2015 Nov 16;16(1):141.
Non-steroidal anti-inflammatory drugs and the risk of head and neck cancer: A case-control analysis.
Becker C, Wilson JC, Jick SS, Meier CR.
International journal of cancer. Journal international du cancer 2015 Nov 15;137(10):2424-
31.
Effects of five preoperative cardiovascular drugs on mortality after coronary artery bypass surgery: A retrospective analysis of an observational study of 16   192 patients.
Venkatesan S, Okoli GN, Mozid AM, Pickworth TWH, Grocott MPW, Sanders RD, Myles P.
Eur J Anaesthesiol 2016 01;33(1):49-57. [Epub released Nov 2015]
Preventing and Lessening Exacerbations of Asthma in School-aged children Associated with a
New Term (PLEASANT): Recruiting Primary Care Research Sites-the PLEASANT experience.
Horspool MJ, Julious SA, Mooney C, May R, Sully B, Smithson WH.
NPJ primary care respiratory medicine 2015 Nov 12;25:15066.
Development and validation of risk prediction equations to estimate future risk of blindness and lower limb amputation in patients with diabetes: cohort study.
Hippisley-Cox J, Coupland C.
BMJ 2015 Nov 11;351:h5441.
Any versus long-term prescribing of high risk medications in older people using 2012 Beers
Criteria: results from three cross-sectional samples of primary care records for 2003/4,
2007/8 and 2011/12.
Ble A, Masoli JAH, Barry HE, Winder RE, Tavakoly B, Henley WE, Kuchel GA, Valderas JM,
Melzer D, Richards SH.
BMC geriatrics 2015 Nov 05;15:146.

44
45
46
47
48
49
50
51
52
53
54
55
56
What are the effects of varenicline compared with nicotine replacement therapy on long-term smoking cessation and clinically important outcomes? Protocol for a prospective cohort study.
Davies NM, Taylor G, Taylor AE, Thomas KH, Windmeijer F, Martin RM, Munafò MR.
BMJ open 2015 Nov 05;5(11):e009665.
Use of Incretin Agents and Risk of Pancreatic Cancer: A Population-Based Cohort Study.
Knapen LM, van Dalem J, Keulemans YC, van Erp N,P., Bazelier MT, De Bruin M,L., Leufkens
HGM, Croes S, Neef C, de Vries F, Driessen JHM.
Diabetes Obes Metab 2015 Nov 05.
Changes in the incidence, prevalence and mortality of bronchiectasis in the UK from 2004 to
2013: a population-based cohort study.
Quint JK, Millett ERC, Joshi M, Navaratnam V, Thomas SL, Hurst JR, Smeeth L, Brown JS.
The European respiratory journal 2016 01;47(1):186-93. [Epub released Nov 2015]
Examining variations in prescribing safety in UK general practice: cross sectional study using the Clinical Practice Research Datalink.
Stocks SJ, Kontopantelis E, Akbarov A, Rodgers S, Avery AJ, Ashcroft DM.
BMJ 2015 Nov 03;351:h5501.
The Use of Glyburide Compared With Other Sulfonylureas and the Risk of Cancer in Patients
With Type 2 Diabetes.
Tuccori M, Wu JW, Yin H, Majdan A, Azoulay L.
Diabetes Care 2015 11;38(11):2083-9.
Increasing incidence of non-valvular atrial fibrillation in the UK from 2001 to 2013.
Martinez C, Katholing A, Wallenhorst C, Granziera S, Cohen AT, Freedman SB.
Heart 2015 Nov 01;101(21):1748-1754.
Risk of venous thromboembolism in children after general surgery.
Humes DJ, Nordenskjöld A, Walker AJ, West J, Ludvigsson JF.
J Pediatr Surg 2015 11;50(11):1870-3.
Prevalence of hypercalcemia of malignancy among cancer patients in the UK: analysis of the
Clinical Practice Research Datalink database.
Jick S, Li L, Gastanaga VM, Liede A.
Cancer Epidemiology 2015 Dec 01;39(6):901-907. [Epub released Nov 2015]
Inflammatory Bowel Disease and the Risk of Autoimmune Diseases.
Wilson JC, Furlano RI, Jick SS, Meier CR.
Journal of Crohn's & colitis 2016 02;10(2):186-93. [Epub released Oct 2015]
Comparative Performance of ATRIA, CHADS2, and CHA2DS2-VASc Risk Scores Predicting
Stroke in Patients With Atrial Fibrillation: Results From a National Primary Care Database.
Van DH, Klungel OH, Singer DE, Leufkens HGM, Van Staa TP.
J Am Coll Cardiol 2015 Oct 27;66(17):1851-1859.
Calculating Total Health Service Utilisation and Costs from Routinely Collected Electronic
Health Records Using the Example of Patients with Irritable Bowel Syndrome Before and After
Their First Gastroenterology Appointment.
Canavan C, West J, Card T.
Pharmacoeconomics 2016 02;34(2):181-94. [Epub released Oct 2015]
Modelling estimates of the burden of Respiratory Syncytial virus infection in adults and the elderly in the United Kingdom.
Fleming DM, Taylor RJ, Lustig RL, Schuck-Paim C, Haguinet F, Webb DJ, Logie J, Matias G,
Taylor S.
BMC Infectious Diseases 2015 Oct 23;15(1).
Patients who discontinued statin treatment: a protocol for cohort study using primary care data.
Vinogradova Y, Coupland C, Brindle P, Hippisley-Cox J.
BMJ open 2015 Oct 22;5(10):e008701.

57
58
59
60
61
62
63
64
65
66
67
68
Health and Employment after Fifty (HEAF): a new prospective cohort study.
Palmer KT, Walker-Bone K, Harris EC, Linaker C, D'Angelo S, Sayer AA, Gale CR, Evandrou M, van Staa T, Cooper C, Coggon D.
BMC Public Health 2015 Oct 19;15(1):1071.
The burden of co-morbidity in Systemic Lupus Erythematosus in the United Kingdom 1999-
2012.
Rees F, Doherty M, Grainge M, Lanyon P, Davenport G, Zhang W.
Arthritis care & research 2015 Oct 16.
No evidence for a decreased risk of thyroid cancer in association with use of metformin or other antidiabetic drugs: A case-control study.
Becker C, Jick SS, Meier CR, Bodmer M.
BMC Cancer 2015 Oct 16;15(1).
Development and Validation of the RxDx-Dementia Risk Index to Predict Dementia in Patients with Type 2 Diabetes and Hypertension.
Mehta HB, Mehta V, Tsai C, Chen H, Aparasu R, Johnson ML.
Journal of Alzheimer's disease : JAD 2015 Oct 15.
Risk of Ischaemic Heart Disease in Patients with Inflammatory Bowel Disease: Cohort Study
Using the General Practice Research Database.
Close H, Mason JM, Wilson DW, Hungin AP, Jones R, Rubin G.
PloS one 2015 Oct 13;10(10):e0139745.
The effect of pre-diagnostic vitamin D supplementation on cancer survival in women: a cohort study within the UK Clinical Practice Research Datalink.
Jeffreys M, Redaniel MT, Martin RM.
BMC Cancer 2015 Oct 12;15:670.
Serotonin-norepinephrine reuptake inhibitors and the risk of AKI: A cohort study of eight administrative databases and meta-analysis.
Renoux C, Lix LM, Patenaude V, Bresee LC, Paterson JM, Lafrance J, Tamim H, Mahmud SM,
Alsabbagh MW, Hemmelgarn B, Dormuth CR, Pierre E, Suissa S, Hemmelgarn BR, Teare GF,
Martens PJ, Caetano P, Chateau D, Henry DA, LeLorier J, Levy AR, Ernst P, Platt RW, Sketris
IS.
Clinical Journal of the American Society of Nephrology 2015 Oct 07;10(10):1716-1722.
Factors Predictive of Weight Gain and Implications for Modeling in Type 2 Diabetes Patients
Initiating Metformin and Sulfonylurea Combination Therapy.
Gordon JP, Evans M, Puelles J, McEwan PC.
Diabetes Therapy 2015 Dec 01;6(4):495-507. [Epub released Oct 2015]
Adherence to NICE guidance on glucagon-like peptide-1 receptor agonists among patients with type 2 diabetes mellitus: an evaluation using the Clinical Practice Research Datalink.
Jameson K, D'Oca K, Leigh P, Murray-Thomas T.
Curr Med Res Opin 2016 Jan 02;32(1):49-60. [Epub released Oct 2015]
Benzodiazepine Use and Risk of Developing Alzheimer's Disease or Vascular Dementia: A
Case-Control Analysis.
Imfeld P, Bodmer M, Jick SS, Meier CR.
Drug safety 2015 10;38(10):909-19.
Benzodiazepines and risk of death: Results from two large cohort studies in France and UK.
Palmaro A, Dupouy J, Lapeyre-Mestre M.
European Neuropsychopharmacology 2015 10;25(10):1566-1577.
Development of processes allowing near real-time refinement and validation of triage tools during the early stage of an outbreak in readiness for surge: the FLU-CATs Study.
Venkatesan S, Myles PR, McCann G, Kousoulis AA, Hashmi M, Belatri R, Boyle E, Barcroft A, van Staa TP, Kirkham JJ, Nguyen Van Tam JS, Williams TJ, Semple MG.

69
70
71
72
73
74
75
76
77
78
79
80
Health Technol Assess 2015 10;19(89):1-132.
Estimating the diagnostic accuracy of rheumatoid factor in UK primary care: a study using the
Clinical Practice Research Datalink.
Miller A, Nightingale AL, Sammon CJ, Mahtani KR, Holt TA, McHugh NJ, Luqmani RA.
Rheumatology (Oxford) 2015 10;54(10):1882-9.
Use of Dipeptidyl-Peptidase-4 Inhibitors and the Risk of Pneumonia: A Population-Based
Cohort Study.
Wvan der Zanden R, de Vries F, Lalmohamed A, Driessen JHM, de Boer A, Rohde G, Neef C, den Heijer C.
PloS one 2015 Oct 15;10(10):e0139367.
Smoke-free legislation and the incidence of paediatric respiratory infections and wheezing/asthma: interrupted time series analyses in the four UK nations.
Been JV, Szatkowski L, van Staa T, Leufkens HG, van Schayck O,C., Sheikh A, de Vries F,
Souverein P.
Scientific reports 2015 Oct 14;5:15246.
Acute kidney injury in stable COPD and at exacerbation.
Barakat MF, McDonald HI, Collier TJ, Smeeth L, Nitsch D, Quint JK.
International journal of chronic obstructive pulmonary disease 2015 Sep 28;10:2067-77.
Prevalence of metabolic syndrome and its components among men with and without clinical benign prostatic hyperplasia: a large, cross-sectional, UK epidemiological study.
DiBello JR, Ioannou C, Rees J, Challacombe B, Maskell J, Choudhury N, Kastner C, Kirby M.
BJU Int 2016 05;117(5):801-8. [Epub released Sep 2015]
Variation in the risk of venous thromboembolism following colectomy.
Humes DJ, Walker AJ, Blackwell J, Hunt BJ, West J.
Br J Surg 2015 12;102(13):1629-38. [Epub released Sep 2015]
The impact of the 'Better Care Better Value' prescribing policy on the utilisation of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers for treating hypertension in the UK primary care setting: longitudinal quasi-experimental design.
Baker A, Chen L, Elliott RA, Godman B.
BMC health services research 2015 Sep 10;15:367.
Development and validation of risk prediction equations to estimate future risk of heart failure in patients with diabetes: a prospective cohort study.
Hippisley-Cox J, Coupland C.
BMJ open 2015 Sep 09;5(9):e008503.
Do health checks improve risk factor detection in primary care? Matched cohort study using electronic health records.
Forster AS, Burgess C, Dodhia H, Fuller F, Miller J, McDermott L, Gulliford MC.
Journal of public health (Oxford, England) 2015 Sep 07.
Oral and inhaled glucocorticoid use and risk of Achilles or biceps tendon rupture: a populationbased case-control study.
Spoendlin J, Meier C, Jick SS, Meier CR.
Ann Med 2015 09;47(6):492-8.
Digoxin use after diagnosis of colorectal cancer and survival: A population-based cohort study.
Karasneh RA, Murray LJ, Hughes CM, Cardwell CR.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for
Cancer Research, cosponsored by the American Society of Preventive Oncology 2015
11;24(11):1804-7.
Remission of Type 2 Diabetes Mellitus in Patients After Different Types of Bariatric Surgery: A
Population-Based Cohort Study in the United Kingdom.
Yska JP, van Roon EN, de Boer A, Leufkens HGM, Wilffert B, de Heide LJM, de Vries F,
Lalmohamed A.

81
82
83
84
85
86
87
88
89
90
91
92
93
JAMA Surgery 2015 12;150(12):1126-1133. [Epub released Sep 2015]
Use of thiazolidinediones and the risk of elective hip or knee replacement: a population based case-control study.
Nielen JTH, de Vries F, Dagnelie PC, van den Bemt B,J.F., Emans PJ, Lalmohamed A, de Boer
A, Boonen AERCH.
Br J Clin Pharmacol 2016 02;81(2):370-8. [Epub released Sep 2015]
Epidemiology of multiple sclerosis: results from a large observational study in the UK.
Jick SS, Li L, Falcone GJ, Vassilev ZP, Wallander M
J Neurol 2015 09;262(9):2033-41.
Safety of Fluticasone Propionate Prescribed for Asthma During Pregnancy: A UK Population-
Based Cohort Study.
Charlton RA, Snowball JM, Nightingale AL, Davis KJ
The journal of allergy and clinical immunology.In practice 2015 Sep;3(5):772-779.e3
Probability of an Obese Person Attaining Normal Body Weight: Cohort Study Using Electronic
Health Records.
Fildes A, Charlton J, Rudisill C, Littlejohns P, Prevost AT, Gulliford MC.
Am J Public Health 2015 09;105(9):e54-9.
The effect of sibutramine prescribing in routine clinical practice on cardiovascular outcomes: a cohort study in the United Kingdom.
Hayes JF, Bhaskaran K, Batterham R, Smeeth L, Douglas I.
International journal of obesity (2005) 2015 09;39(9):1359-64.
Use of demographic and pharmacy data to identify patients included within both the Clinical
Practice Research Datalink (CPRD) and The Health Improvement Network (THIN).
Carbonari DM, Saine ME, Newcomb CW, Blak B, Roy JA, Haynes K, Wood J, Gallagher AM,
Bhullar H, Cardillo S, Henessy S, Strom BL, Lo Re V.
Pharmacoepidemiol Drug Saf 2015 09;24(9):999-1003.
Coverage of a national cardiovascular risk assessment and management programme (NHS
Health Check): Retrospective database study.
Chang KC, Soljak M, Lee JT, Woringer M, Johnston D, Khunti K, Majeed A, Millett C.
Prev Med 2015 09;78:1-8.
Psoriasis and the Risk of Major Cardiovascular Events: Cohort Study Using the Clinical Practice
Research Datalink.
Parisi R, Rutter MK, Lunt M, Young HS, Symmons DPM, Griffiths CEM, Ashcroft DM.
J Invest Dermatol 2015 09;135(9):2189-97.
Increasing incidence of non-valvular atrial fibrillation in the UK from 2001 to 2013.
Martinez C, Katholing A, Wallenhorst C, Granziera S, Cohen AT, Freedman SB.
Heart 2015 Aug 25.
Burden of Illness in UK Subjects with Reported Respiratory Infections Vaccinated or
Unvaccinated against Influenza: A Retrospective Observational Study.
Pockett RD, Watkins J, McEwan P, Meier G.
PloS one 2015 Aug 19;10(8):e0134928.
Morbidity and medication in a large population of individuals with Down syndrome compared to the general population.
Alexander M, Petri H, Ding Y, Wandel C, Khwaja O, Foskett N.
Dev Med Child Neurol 2016 03;58(3):246-54. [Epub released Aug 2015]
Influenza vaccination and risk of stroke: Self-controlled case-series study.
Asghar Z, Coupland C, Siriwardena N.
Vaccine 2015 Oct 05;33(41):5458-5463.
The impact of persistence with bisphosphonates on health resource utilization and fracture risk in the UK: a study of patient records from the UK Clinical Practice Research Datalink.

94
95
96
97
98
99
100
101
102
103
104
105
Ferguson S, Feudjo Tepie M, Taylor A, Roddam A, Critchlow C, Iqbal M, Spangler L, Bayly J.
J Eval Clin Pract 2015 Aug 16.
Causes of death in people with liver cirrhosis in England compared with the general population: A population-based cohort study.
Ratib S, Fleming KM, Crooks CJ, Walker AJ, West J.
Am J Gastroenterol 2015 Aug 13;110(8):1149-1158.
Antiepileptic drug prescribing before, during and after pregnancy: a study in seven European regions.
Charlton R, Garne E, Wang H, Klungsøyr K, Jordan S, Neville A, Pierini A, Hansen A, Engeland
A, Gini R, Thayer D, Bos J, Puccini A, Nybo Andersen A, Dolk H, de Jong-van dB.
Pharmacoepidemiol Drug Saf 2015 11;24(11):1144-54.
Antiepileptic drugs and the risk of ischaemic stroke and myocardial infarction: a populationbased cohort study.
Renoux C, Dell'Aniello S, Saarela O, Filion KB, Boivin J.
BMJ open 2015 Aug 12;5(8):e008365.
Influence of metformin intake on the risk of bladder cancer in type 2 diabetes patients.
Goossens ME, Buntinx F, Zeegers MP, Driessen JHM, De Bruin M,L., de Vries F.
Br J Clin Pharmacol 2015 12;80(6):1464-72. [Epub released Aug 2015]
Metformin use and survival after colorectal cancer: A population-based cohort study.
Mc Menamin Ú,C., Murray LJ, Hughes CM, Cardwell CR.
International journal of cancer.Journal international du cancer 2016 Jan 15;138(2):369-79.
[Epub released Aug 2015]
The incidence of childhood and adolescent seizures in the UK from 1999 to 2011: A retrospective cohort study using the Clinical Practice Research Datalink.
Sammon CJ, Charlton RA, Snowball J, Weil JG.
Vaccine 2015 Dec 16;33(51):7364-9. [Epub released Aug 2015]
Delay in treatment intensification increases the risks of cardiovascular events in patients with type 2 diabetes.
Paul SK, Klein K, Thorsted BL, Wolden ML, Khunti K.
Cardiovascular Diabetology 2015 Aug 07;14(1).
The risk of acute liver injury among users of antibiotic medications: a comparison of case-only studies.
Brauer R, Ruigómez A, Klungel O, Reynolds R, Feudjo Tepie M, Smeeth L, Douglas I.
Pharmacoepidemiol Drug Saf 2015 Aug 06.
Therapy persistence in newly diagnosed non-valvular atrial fibrillation treated with warfarin or
NOAC. A cohort study.
Martinez C, Katholing A, Wallenhorst C, Freedman SB.
Thromb Haemost 2015 Dec 22;115(1):31-9. [ Epub released Aug 2015]
Did NICE guidelines and the Quality Outcomes Framework change GP antidepressant prescribing in England? Observational study with time trend analyses 2003-2013.
Kendrick T, Stuart B, Newell C, Geraghty AWA, Moore M.
J Affect Disord 2015 Aug 04;186:171-177.
Can the publication of guidelines change the management of early rheumatoid arthritis? An interrupted time series analysis from the United Kingdom.
Judge A, Wallace G, Prieto-Alhambra D, Arden NK, Edwards CJ.
Rheumatology (Oxford) 2015 12;54(12):2244-8. [Epub released Aug 2015]
Bone fracture risk is not associated with the use of glucagon-like peptide-1 receptor agonists: a population-based cohort analysis.
Driessen JHM, Henry RMA, van Onzenoort H,A.W., Lalmohamed A, Burden AM, Prieto-
Alhambra D, Neef C, Leufkens HGM, de Vries F.
Calcif Tissue Int 2015 08;97(2):104-12.

106
107
108
109
110
111
112
113
114
115
116
Contemporary Risk Estimates of Three HbA1c Variables for Myocardial Infarction in 101,799
Patients Following Diagnosis of Type 2 Diabetes.
Olsson M, Schnecke V, Cabrera C, Skrtic S, Lind M.
Diabetes Care 2015 08;38(8):1481-6.
Can different primary care databases produce comparable estimates of burden of disease: results of a study exploring venous leg ulceration.
Petherick ES, Pickett KE, Cullum NA.
Fam Pract 2015 08;32(4):374-80.
Patient characteristics and treatment patterns for patients with benign prostatic hyperplasia, erectile dysfunction or co-occurring benign prostatic hyperplasia and erectile dysfunction in general practices in the UK: a retrospective observational study.
Ilo D, Raluy-Callado M, Graham-Clarke P, Sadasivan R, Birt J, Donaldson R, Zhu E, Kirby MG,
Neasham D.
Int J Clin Pract 2015 08;69(8):853-62.
Estimated glomerular filtration rate progression in UK primary care patients with type 2 diabetes and diabetic kidney disease: a retrospective cohort study.
Cid Ruzafa J, Paczkowski R, Boye KS, Di Tanna ,G.L., Sheetz MJ, Donaldson R, Breyer MD,
Neasham D, Voelker JR.
Int J Clin Pract 2015 08;69(8):871-82.
Individuals With Type 2 Diabetes Mellitus Are at an Increased Risk of Gout But This Is Not Due to Diabetes: A Population-Based Cohort Study.
Wijnands JMA, van Durme, Caroline Marie,Pierre Ghislaine, Driessen JHM, Boonen A, Klop C,
Leufkens B, Cooper C, Stehouwer CDA, de Vries F.
Medicine 2015 08;94(32):e1358.
Association between benzodiazepine use and exacerbations and mortality in patients with asthma: a matched case-control and survival analysis using the United Kingdom Clinical
Practice Research Datalink.
Nakafero G, Sanders RD, Nguyen-Van-Tam J,S., Myles PR.
Pharmacoepidemiol Drug Saf 2015 08;24(8):793-802.
Clopidogrel use and cancer-specific mortality: a population-based cohort study of colorectal, breast and prostate cancer patients.
Hicks BM, Murray LJ, Hughes C, Cardwell CR.
Pharmacoepidemiol Drug Saf 2015 08;24(8):830-40.
Determinants of oral anticoagulation control in new warfarin patients: Analysis using data from Clinical Practice Research Datalink.
MacEdo AF, Bell J, McCarron C, Conroy R, Richardson J, Scowcroft A, Sunderland T, Rotheram
N.
Thromb Res 2015 Aug 01;136(2):250-260.
Differences in Health at Age 100 According to Sex: Population-Based Cohort Study of
Centenarians Using Electronic Health Records.
Hazra NC, Dregan A, Jackson S, Gulliford MC.
J Am Geriatr Soc 2015 07;63(7):1331-7.
Risk of spontaneous abortion and other pregnancy outcomes in 15-25 year old women exposed to human papillomavirus-16/18 AS04-adjuvanted vaccine in the United Kingdom.
Baril L, Rosillon D, Willame C, Angelo MG, Zima J, van den Bosch J,H., Van Staa T, Boggon R,
Bunge EM, Hernandez-Diaz S, Chambers CD.
Vaccine 2015 Nov 27;33(48):6884-6891. [Epub released Jul 2015]
Antidiabetic and cardiovascular drug utilisation in patients diagnosed with type 2 diabetes mellitus over the age of 80 years: a population-based cohort study.
Hamada S, Gulliford MC.
Age Ageing 2015 07;44(4):566-73.

117
118
119
120
121
122
123
124
125
126
127
128
CKD and the risk of acute, community-acquired infections among older people with diabetes mellitus: A retrospective cohort study using electronic health records.
McDonald HI, Thomas SL, Millett ERC, Nitsch D.
American Journal of Kidney Diseases 2015 Jul 01;66(1):60-68.
Antipsychotic Drug Use and the Risk of Seizures: Follow-up Study with a Nested Case-Control
Analysis.
Bloechliger M, Rüegg S, Jick SS, Meier CR, Bodmer M.
CNS drugs 2015 07;29(7):591-603.
Identification of incident poisoning, fracture and burn events using linked primary care, secondary care and mortality data from England: implications for research and surveillance.
Baker R, Tata LJ, Kendrick D, Orton E.
Injury prevention : journal of the International Society for Child and Adolescent Injury
Prevention 2016 02;22(1):59-67. [Epub released Jul 2015]
Anti-osteoporosis drug prescribing after hip fracture in the UK: 2000-2010.
Klop C, Gibson-Smith D, Elders PJM, Welsing PMJ, Leufkens HGM, Harvey NC, Bijlsma JWJ, van Staa T, De Vries F.
Osteoporosis international : a journal established as result of cooperation between the
European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
2015 07;26(7):1919-28.
Are ECG monitoring recommendations before prescription of QT-prolonging drugs applied in daily practice? The example of haloperidol.
Warnier MJ, Rutten FH, Souverein PC, de Boer A, Hoes AW, De Bruin ML.
Pharmacoepidemiol Drug Saf 2015 Jul 01;24(7):701-708.
Glitazone treatment and incidence of parkinson’s disease among people with diabetes: A retrospective cohort study.
Brauer R, Bhaskaran K, Chaturvedi N, Dexter DT, Smeeth L, Douglas I.
PLoS Medicine 2015 Jul 01;12(7).
An algorithm to improve diagnostic accuracy in diabetes in computerised problem orientated medical records (POMR) compared with an established algorithm developed in episode orientated records (EOMR).
De Lusignan S, Liaw S, Dedman D, Khunti K, Sadek K, Jones S.
Journal of innovation in health informatics 2015 Jun 05;22(2):255-64.
Risk of bladder cancer in patients with diabetes: a retrospective cohort study.
Goossens ME, Zeegers MP, Bazelier MT, De Bruin M,L., Buntinx F, de Vries F.
BMJ open 2015 Jun 01;5(6):e007470.
Digoxin use after diagnosis of breast cancer and survival: a population-based cohort study.
Karasneh RA, Murray LJ, Mc Menamin Ú,C., Hughes CM, Cardwell CR.
Breast Cancer Res Treat 2015 06;151(3):661-9.
The effectiveness of pharmaceutical interventions for obesity: weight loss with orlistat and sibutramine in a United Kingdom population-based cohort.
Douglas IJ, Bhaskaran K, Batterham RL, Smeeth L.
Br J Clin Pharmacol 2015 06;79(6):1020-7.
Comparison of diabetes-associated secondary healthcare utilization between alternative oral antihyperglycaemic dual therapy combinations with metformin in patients with type 2 diabetes: an observational cohort study.
Strongman H, D'Oca K, Langerman H, Das R.
Diabetes Obes Metab 2015 06;17(6):573-80.
Data Resource Profile: Clinical Practice Research Datalink (CPRD).
Herrett E, Gallagher AM, Bhaskaran K, Forbes H, Mathur R, Staa Tv, Smeeth L.

129
130
131
132
133
134
135
136
137
138
139
140
Int J Epidemiol 2015 Jun 01;44(3):827-836.
5α-Reductase Inhibitors and the Risk of Cancer-Related Mortality in Men With Prostate Cancer.
Azoulay L, Eberg M, Benayoun S, Pollak M.
JAMA oncology 2015 Jun 01;1(3):314-20.
BMI and risk of dementia in two million people over two decades: a retrospective cohort study.
Qizilbash N, Gregson J, Johnson ME, Pearce N, Douglas I, Wing K, Evans SJW, Pocock SJ.
The lancet.Diabetes & endocrinology 2015 06;3(6):431-6.
Use of combined oral contraceptives and risk of venous thromboembolism: nested casecontrol studies using the QResearch and CPRD databases.
Vinogradova Y, Coupland C, Hippisley-Cox J.
BMJ 2015 May 26;350:h2135.
Post-diagnostic oral bisphosphonate use and colorectal cancer mortality: a population-based cohort study within the UK Clinical Practice Research Datalink.
Hicks BM, Murray LJ, Hughes C, Cardwell CR.
Br J Cancer 2015 May 19.
Quantifying the risk of non-Hodgkin lymphoma in symptomatic primary care patients aged
≥40 years: A large case-control study using electronic records.
Shephard EA, Neal RD, Rose PW, Walter FM, Hamilton WT.
British Journal of General Practice 2015 May 01;65(634):e281-e288.
Quantifying the risk of Hodgkin lymphoma in symptomatic primary care patients aged ≥40 years: A case-control study using electronic records.
Shephard EA, Neal RD, Rose PW, Walter FM, Hamilton WT.
British Journal of General Practice 2015 May 01;65(634):e289-e294.
Patient-doctor continuity and diagnosis of cancer: Electronic medical records study in general practice.
Ridd MJ, Santos Ferreira DL, Montgomery AA, Salisbury C, Hamilton W.
British Journal of General Practice 2015 May 01;65(634):e305-e311.
Statin use and survival from lung cancer: a population-based cohort study.
Cardwell CR, Mc Menamin Ú, Hughes CM, Murray LJ.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for
Cancer Research, cosponsored by the American Society of Preventive Oncology 2015
05;24(5):833-41.
Prevalence and incidence rates of cardiovascular, autoimmune, and other diseases in patients with psoriatic or psoriatic arthritis: A retrospective study using Clinical Practice Research
Datalink.
Edson-Heredia E, Zhu B, Lefevre C, Wang M, Barrett A, Bushe CJ, Cox A, Wu JJ, Maeda-
Chubachi T.
Journal of the European Academy of Dermatology and Venereology 2015 May 01;29(5):955-
963.
Missing laboratory test data in electronic general practice records: Analysis of rheumatoid factor recording in the clinical practice research datalink.
Sammon CJ, Miller A, Mahtani KR, Holt TA, Mchugh NJ, Luqmani RA, Nightingale AL.
Pharmacoepidemiol Drug Saf 2015 May 01;24(5):504-509.
Diagnostic intervals and its association with breast, prostate, lung and colorectal cancer survival in England: Historical cohort study using the Clinical Practice Research Datalink.
Redaniel MT, Martin RM, Ridd MJ, Wade J, Jeffreys M.
PLoS ONE 2015 May 01;10(5).
Determinants of saxagliptin use among patients with type 2 diabetes mellitus treated with oral anti-diabetic drugs.
Saine ME, Carbonari DM, Newcomb CW, Nezamzadeh MS, Haynes K, Roy JA, Cardillo S,

141
142
143
144
145
146
147
148
149
150
151
152
Hennessy S, Holick CN, Esposito DB, Gallagher AM, Bhullar H, Strom BL, Lo Re V.
BMC pharmacology & toxicology 2015 Apr 02;16(1):8.
Tramadol for noncancer pain and the risk of hyponatremia.
Fournier J, Yin H, Nessim SJ, Montastruc J, Azoulay L.
Am J Med 2015 Apr 01;128(4):418-425.e1.
The association between glucose-lowering drug use and mortality among breast cancer patients with type 2 diabetes.
Vissers PAJ, Cardwell CR, van de Poll-Franse L,V., Young IS, Pouwer F, Murray LJ.
Breast Cancer Res Treat 2015 04;150(2):427-37.
The Combination of DPP-4 Inhibitors Versus Sulfonylureas with Metformin After Failure of
First-line Treatment in the Risk for Major Cardiovascular Events and Death.
Yu OHY, Yin H, Azoulay L.
Canadian Journal of Diabetes 2015 10;39(5):383-389
Impact of Switching From High-Efficacy Lipid-Lowering Therapies to Generic Simvastatin on
LDL-C Levels and LDL-C Goal Attainment Among High-Risk Primary and Secondary Prevention
Populations in the United Kingdom.
Cao X, Ejzykowicz F, Ramey DR, Sajjan S, Ambegaonkar BM, Mavros P, Tunceli K.
Clin Ther 2015 Apr 01;37(4):804-15.
Pharmacotherapeutic strategies for patients treated for depression in UK primary care: a database analysis.
Lamy FX, Chollet J, Clay E, Brignone M, Rive B, Saragoussi D.
Curr Med Res Opin 2015 04;31(4):795-807.
Dipeptidyl peptidase-4 inhibitors and the risk of community-acquired pneumonia in patients with type 2 diabetes.
Faillie JL, Filion KB, Patenaude V, Ernst P, Azoulay L.
Diabetes Obes Metab 2015 04;17(4):379-85.
Prokinetics prescribing in paediatrics: evidence on cisapride, domperidone, and metoclopramide.
Mt-Isa S, Tomlin S, Sutcliffe A, Underwood M, Williamson P, Croft NM, Ashby D.
J Pediatr Gastroenterol Nutr 2015 04;60(4):508-14.
Statin use and risk for primary liver cancer in the clinical practice research datalink.
McGlynn KA, Hagberg K, Chen J, Graubard BI, London WT, Jick S, Sahasrabuddhe VV.
J Natl Cancer Inst 2015 Apr 01;107(4).
Future projections of total hip and knee arthroplasty in the UK: results from the UK Clinical
Practice Research Datalink.
Culliford D, Maskell J, Judge A, Cooper C, Prieto-Alhambra D, Arden NK.
Osteoarthr Cartil 2015 04;23(4):594-600.
Childhood obesity trends from primary care electronic health records in England between
1994 and 2013: population-based cohort study. van Jaarsveld C,H.M., Gulliford MC.
Arch Dis Child 2015 03;100(3):214-9.
The risk of colorectal cancer in patients with type 2 diabetes: associations with treatment stage and obesity.
Peeters PJHL, Bazelier MT, Leufkens HGM, de Vries F, De Bruin M,L.
Diabetes Care 2015 03;38(3):495-502.
Application of multicategory exposure marginal structural models to investigate the association between long-acting beta-agonists and prescribing of oral corticosteroids for asthma exacerbations in the Clinical Practice Research Datalink.
Ali AK, Hartzema AG, Winterstein AG, Segal R, Lu X, Hendeles L.
Value in health : the journal of the International Society for Pharmacoeconomics and
Outcomes Research 2015 03;18(2):260-70.

153
154
155
156
157
158
159
160
161
162
163
164
Improving identification of familial hypercholesterolaemia in primary care: derivation and validation of the familial hypercholesterolaemia case ascertainment tool (FAMCAT).
Weng SF, Kai J, Andrew Neil H, Humphries SE, Qureshi N.
Atherosclerosis 2015 02;238(2):336-43.
Angiotensin receptor blockers and risk of dementia: cohort study in UK Clinical Practice
Research Datalink.
Goh KL, Bhaskaran K, Minassian C, Evans SJW, Smeeth L, Douglas IJ.
Br J Clin Pharmacol 2015 02;79(2):337-50.
Quantifying the risk of multiple myeloma from symptoms reported in primary care patients: A large case-control study using electronic records.
Shephard EA, Neal RD, Rose P, Walter FM, Litt EJ, Hamilton WT.
British Journal of General Practice 2015 Feb 01;65(631):e106-e113.
A comparison of the recording of comorbidity in primary and secondary care by using the
Charlson Index to predict short-term and long-term survival in a routine linked data cohort.
Crooks CJ, West J, Card TR.
BMJ Open 2015;5(6).
Can analyses of electronic patient records be independently and externally validated? Study 2
- The effect of β-adrenoceptor blocker therapy on cancer survival: A retrospective cohort study.
Springate DA, Ashcroft DM, Kontopantelis E, Doran T, Ryan R, Reeves D.
BMJ Open 2015;5(4).
Access to weight reduction interventions for overweight and obese patients in UK primary care: Population-based cohort study.
Booth HP, Prevost AT, Gulliford MC.
BMJ Open 2015;5(1).
Tonsillectomy among children with low baseline acute throat infection consultation rates in UK general practices: A cohort study.
Koshy E, Watt H, Curcin V, Bottle A, Sharland M, Saxena S.
BMJ Open 2015;5(2).
Impact of timing and duration of thiopurine treatment on first perianal surgery in crohn's disease: UK population-based study (1995-2009).
Chhaya V, Saxena S, Cecil E, Subramanian V, Curcin V, Majeed A, Pollok RCG.
Inflamm Bowel Dis 2015;21(2):385-391.
Initial step-up treatment changes in asthmatic children already prescribed inhaled corticosteroids: A historical cohort study.
Turner SW, Richardson K, Burden A, Thomas M, Murray C, Price D. npj Primary Care Respiratory Medicine 2015;25.
Much more medicine for the oldest old: trends in UK electronic clinical records
Melzer, David , Tavakoly, Behrooz , Winder, Rachel E , Masoli, Jane A H , Henley, William E ,
Ble, Alessandro , Richards, Suzanne H
Age and ageing. 2015. 44(1):46-53.
The relative risk of aortic aneurysm in patients with giant cell arteritis compared with the general population of the UK
Robson, Joanna C , Kiran, Amit , Maskell, Joe , Hutchings, Andrew , Arden, Nigel , Dasgupta,
Bhaskar , Hamilton, William , Emin, Akan , Culliford, David , Luqmani, Raashid A
Annals of the rheumatic diseases. 2015. 74(1):129-35.
Increase in the pharmacological management of Type 2 diabetes with pay-for-performance in primary care in the UK
Gallagher, N , Cardwell, C , Hughes, C , O'Reilly, D
Diabetic medicine : a journal of the British Diabetic Association. 2015. 32(1):62-8.

165
166
Statin Use After Diagnosis of Breast Cancer and Survival: A Population-based Cohort Study
Cardwell, Chris R , Hicks, Blanaid M , Hughes, Carmel , Murray, Liam J
Epidemiology (Cambridge, Mass.). 2015. 26(1):68-78.
Implications of lower risk thresholds for statin treatment in primary prevention: Analysis of
CPRD and simulation modelling of annual cholesterol monitoring
McFadden, Emily , Stevens, Richard , Glasziou, Paul , Perera, Rafael
Preventive Medicine. 2015. 70():14-16.
1
2
3
4
5
6
7
8
9
10
Incidence of type 2 diabetes after bariatric surgery: population-based matched cohort study.
Booth H, Khan O, Prevost T, Reddy M, Dregan A, Charlton J, Ashworth M, Rudisill C, Littlejohns P,
Gulliford MC.
The lancet.Diabetes & endocrinology 2014 Dec 01;2(12):963-968.
Evaluating pancreatitis in primary care: a population-based cohort study.
Hazra N, Gulliford M.
The British journal of general practice : the journal of the Royal College of General Practitioners
2014 May 01;64(622):e295-e301.
The opportunities and challenges of pragmatic point-of-care randomised trials using routinely collected electronic records: Evaluations of two exemplar trials. van Staa T, Dyson L, McCann G, Padmanabhan S, Belatri R, Goldacre B, Cassell J, Pirmohamed M,
Torgerson D, Ronaldson S, Adamson J, Taweel A, Delaney B, Mahmood S, Baracaia S, Round T,
Fox R, Hunter T, Gulliford M, Smeeth L.
Health Technol Assess 2014 07;18(43):1-146.
Development of predictive genetic tests for improving the safety of new medicines: the utilization of routinely collected electronic health records.
Wing K, Douglas I, Bhaskaran K, Klungel OH, Reynolds RF, Pirmohamed M, Smeeth L, van Staa,
TP.
Drug Discov Today 2014 04;19(4):361-6.
Antidepressant prescribing in five European countries: Application of common definitions to assess the prevalence, clinical observations, and methodological implications.
Abbing-Karahagopian V, Huerta C, Souverein PC, De Abajo F, Leufkens HGM, Slattery J, Alvarez Y,
Miret M, Gil M, Oliva B, Hesse U, Requena G, De Vries F, Rottenkolber M, Schmiedl S, Reynolds R,
Schlienger RG, De Groot MCH, Klungel OH, Van Staa TP, Van Dijk L, Egberts ACG, Gardarsdottir H,
De Bruin ML.
Eur J Clin Pharmacol 2014 04;70(7):849-857.
Bridging differences in outcomes of pharmacoepidemiological studies: Design and first results of the PROTECT project.
Abbing-Karahagopian V, Kurz X, de Vries F, van Staa TP, Alvarez Y, Hesse U, Hasford J, van Dijk
L, de Abajo FJ, Weil JG, Grimaldi-Bensouda L, Egberts ACG, Reynolds RF, Klungel OH.
Current Clinical Pharmacology 2014;9(2):130-138.
Risk of breast cancer in symptomatic women in primary care: A case-control study using electronic records.
Walker S, Hyde C, Hamilton W.
British Journal of General Practice 2014 Dec 01;64(629):e788-e795.
Completeness and usability of ethnicity data in UK-based primary care and hospital databases.
Mathur R, Bhaskaran K, Chaturvedi N, Leon DA, vanStaa T, Grundy E, Smeeth L.
Journal of public health (Oxford, England) 2014 12;36(4):684-92.
Converting to a common data model: what is lost in translation? : Commentary on "fidelity assessment of a clinical practice research datalink conversion to the OMOP common data model".
Rijnbeek PR.
Drug safety 2014 11;37(11):893-6.
Allopurinol initiation and change in blood pressure in older adults with hypertension.
Beattie CJ, Fulton RL, Higgins P, Padmanabhan S, McCallum L, Walters MR, Dominiczak AF, Touyz

11
12
13
14
15
16
17
18
19
20
21
22
RM, Dawson J.
Hypertension 2014 Nov 01;64(5):1102-1107.
Switch patterns of osteoporosis medication and its impact on persistence among postmenopausal women in the U.K. General Practice Research Database.
Li L, Roddam A, Ferguson S, Feudjo-Tepie M, Taylor A, Jick S.
Menopause 2014 10;21(10):1106-13.
Validity of non-fatal idiopathic serious ventricular arrhythmia in UK-based Clinical Practice
Research Datalink.
Li L, Setoguchi S, Jick S.
Pharmacoepidemiol Drug Saf 2014 09;23(9):999-1001.
The effect of warfarin therapy on breast, colorectal, lung, and prostate cancer survival: a population-based cohort study using the Clinical Practice Research Datalink
O'Rorke, M A , Murray, L J , Hughes, C M , Cantwell, M M , Cardwell, C R
[epub released 2014]
Cancer causes & control : CCC 2015 03;26(3):355-66.
Risk factors for acute exacerbations of COPD in a primary care population: a retrospective observational cohort study
Müllerová, Hana , Shukla, Amit , Hawkins, Adam , Quint, Jennifer
BMJ open. 2014. 4(12):e006171.
Previously diagnosed influenza infections and the risk of developing epilepsy
Wilson, J C , Toovey, S , Jick, S S , Meier, C R
[epub released 2014]
Epidemiol Infect 2015 08;143(11):2408-15.
Sensory impairments, problems of balance and accidental injury at work: a case-control study
Palmer, Keith T , D'Angelo, Stefania , Harris, E Clare , Linaker, Cathy , Coggon, David
[epub released 2014]
Occup Environ Med 2015 03;72(3):195-9.
Glucose, blood pressure and cholesterol levels and their relationships to clinical outcomes in type 2 diabetes: a retrospective cohort study
Kontopantelis, Evangelos , Springate, David A , Reeves, David , Ashcroft, Darren M , Rutter, Martin , Buchan,
Iain , Doran, Tim
[epub released 2014]
Diabetologia 2015 03;58(3):505-18.
Hypoglycemia and Risk of Cardiovascular Disease and All-Cause Mortality in Insulin-Treated People With
Type 1 and Type 2 Diabetes: A Cohort Study
Khunti, Kamlesh , Davies, Melanie , Majeed, Azeem , Thorsted, Brian Larsen , Wolden, Michael Lyng , Paul,
Sanjoy K
[epub released 2014]
Diabetes Care 2015 Feb 01;38(2):316-322.
Tramadol Use and the Risk of Hospitalization for Hypoglycemia in Patients With Noncancer Pain
Fournier, Jean-Pascal , Azoulay, Laurent , Yin, Hui , Montastruc, Jean-Louis , Suissa, Samy
[epub released 2014]
JAMA Internal Medicine 2015 Feb 01;175(2):186-193.
Pioglitazone and bladder cancer risk: a multipopulation pooled, cumulative exposure analysis
Levin, Daniel , Bell, Samira , Sund, Reijo , Hartikainen, Sirpa A , Tuomilehto, Jaakko , Pukkala, Eero ,
Keskimäki, Ilmo , Badrick, Ellena , Renehan, Andrew G , Buchan, Iain E , Bowker, Samantha L , Minhas-
Sandhu, Jasjeet K , Zafari, Zafar , Marra, Carlo , Johnson, Jeffrey A , Stricker, Bruno H , Uitterlinden, Andrè G
, Hofman, Albert , Ruiter, Rikje , de Keyser, Catherine E , MacDonald, Thomas M , Wild, Sarah H , McKeigue,
Paul M , Colhoun, Helen M
[epub released 2014]
Diabetologia 2015 03;58(3):493-504.
Incidence Rates of Clinically Significant Tinnitus: 10-Year Trend From a Cohort Study in England
Martinez, Carlos , Wallenhorst, Christopher , McFerran, Don , Hall, Deborah A
[epub released 2014]
Ear Hear 2015 May;36(3):e69-75.
Social and material deprivation and the cost-effectiveness of an intervention to promote physical activity: cohort study and Markov model

23
24
25
26
27
28
29
30
31
32
33
34
35
36
Gulliford, Martin , Charlton, Judith , Bhattarai, Nawaraj , Rudisill, Caroline
Journal of public health (Oxford, England). 2014. 36(4):674-83.
Completeness and usability of ethnicity data in UK-based primary care and hospital databases
Mathur, Rohini , Bhaskaran, Krishnan , Chaturvedi, Nish , Leon, David A , vanStaa, Tjeerd , Grundy, Emily ,
Smeeth, Liam
Journal of public health (Oxford, England). 2014. 36(4):684-92.
Risk of fracture in patients with Charcot-Marie-Tooth disease
Pouwels, Sander , de Boer, Anthonius , Leufkens, Hubert G M , Weber, Wim E J , Cooper, Cyrus , de Vries,
Frank
Muscle & nerve. 2014. 50(6):919-24.
The use of antidepressants and the risk of idiopathic pulmonary arterial hypertension
Fox, Benjamin D , Azoulay, Laurent , Dell'Aniello, Sophie , Langleben, David , Lapi, Francesco , Benisty,
Jacques , Suissa, Samy
The Canadian journal of cardiology. 2014. 30(12):1633-9.
Are IBD patients more likely to have a prior diagnosis of irritable bowel syndrome? Report of a case-control study in the General Practice Research Database
Card, Timothy R , Siffledeen, Jesse , Fleming, Kate M
United European gastroenterology journal. 2014. 2(6):505-12.
The use of antidepressants and the risk of chronic atrial fibrillation
Lapi, F , Azoulay, L , Kezouh, A , Benisty, I J , Matok, I , Mugelli, A , Suissa, S
Journal of clinical pharmacology. 2014. Nov 26, 2014
[epub released 2014]
J Clin Pharmacol 2015 04;55(4):423-430.
Evaluating the validity of clinical codes to identify cataract and glaucoma in the UK Clinical Practice Research
Datalink
Kang, Elizabeth M , Pinheiro, Simone P , Hammad, Tarek A , Abou-Ali, Adel
[epub released 2014]
Pharmacoepidemiol Drug Saf 2015 Jan 01;24(1):38-44.
Palliative care among heart failure patients in primary care: A comparison to cancer patients using english family practice data
Gadoud, Amy , Kane, Eleanor , Macleod, Una , Ansell, Pat , Oliver, Steven , Johnson, Miriam
PLoS ONE. 2014. 9(11):.
Nonsteroidal anti-inflammatory drugs and the risk of nonmelanoma skin cancer
Reinau, Daphne , Surber, Christian , Jick, Susan S , Meier, Christoph R
International journal of cancer. 2014. Nov 24, 2014
[epub released 2014]
International Journal of Cancer 2015 Jul 01;137(1):144-153.
Tramadol for non-cancer pain and the risk of hyponatremia
Fournier, Jean-Pascal , Yin, Hui , Nessim, Sharon J , Montastruc, Jean-Louis , Azoulay, Laurent
The American journal of medicine. 2014. Nov 22, 2014
Glucose-lowering with exogenous insulin monotherapy in type 2 diabetes: dose association with all-cause mortality, cardiovascular events, and incident cancer
Holden, Sarah E , Jenkins-Jones, Sara , Morgan, Christopher Ll , Schernthaner, Guntram , Currie, Craig J
[epub released 2014]
Diabetes Obes Metab 2015 04;17(4):350-62.
The use of aspirin and the risk of mortality in patients with prostate cancer
Assayag, Jonathan , Pollak, Michael N , Azoulay, Laurent
[epub released 2014]
J Urol 2015 Apr 01;193(4):1220-1225.
Use of dipeptidyl peptidase-4 inhibitors for type 2 diabetes mellitus and risk of fracture
Driessen, Johanna H M , van Onzenoort, Hein A W , Henry, Ronald M A , Lalmohamed, Arief , van den Bergh,
Joop P , Neef, Cees , Leufkens, Hubert G M , de Vries, Frank
Bone. 2014. 68():124-30.
Antihypertensive agents acting on the renin-angiotensin system and the risk of sepsis
Dial, Sandra , Nessim, Sharon J , Kezouh, Abbas , Benisty, Jacques , Suissa, Samy
British journal of clinical pharmacology. 2014. 78(5):1151-8.
Long-term use of 5α-reductase inhibitors and the risk of male breast cancer
Duijnhoven, Ruben G , Straus, Sabine M J M , Souverein, Patrick C , de Boer, Anthonius , Bosch, J L H Ruud ,

37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
Hoes, Arno W , De Bruin, Marie L
Cancer causes & control : CCC. 2014. 25(11):1577-82.
Metformin and the risk of head and neck cancer: a case-control analysis
Becker, C , Jick, S S , Meier, C R , Bodmer, M
Diabetes, obesity & metabolism. 2014. 16(11):1148-54.
Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin or sulphonylurea monotherapy and matched, non-diabetic controls
Bannister, C A , Holden, S E , Jenkins-Jones, S , Morgan, C Ll , Halcox, J P , Schernthaner, G , Mukherjee, J ,
Currie, C J
Diabetes, obesity & metabolism. 2014. 16(11):1165-73.
Fidelity assessment of a clinical practice research datalink conversion to the OMOP common data model
Matcho, Amy , Ryan, Patrick , Fife, Daniel , Reich, Christian
Drug safety. 2014. 37(11):945-59.
Cardiovascular risk associated with sodium-containing medicines
Wei, Li , Mackenzie, Isla S. , MacDonald, Thomas M. , George, Jacob
Expert Opinion on Drug Safety. 2014. 13(11):1515-1523.
Allopurinol initiation and change in blood pressure in older adults with hypertension
Beattie, Catherine J , Fulton, Rachael L , Higgins, Peter , Padmanabhan, Sandosh , McCallum, Linsay , Walters,
Matthew R , Dominiczak, Anna F , Touyz, Rhian M , Dawson, Jesse
Hypertension. 2014. 64(5):1102-7.
Retrospective database study to assess the economic impact of hip fracture in the United Kingdom
Lambrelli, Dimitra , Burge, Russel , Raluy-Callado, Mireia , Chen, Shih-Yin , Wu, Ning , Schoenfeld, Michael
J
Journal of medical economics. 2014. 17(11):817-25.
The risk of major and any (non-hip) fragility fracture after hip fracture in the United Kingdom: 2000-2010
Gibson-Smith, D , Klop, C , Elders, P J M , Welsing, P M J , van Schoor, N , Leufkens, H G M , Harvey, N C , van Staa, T P , de Vries, F
Osteoporosis international. 2014. 25(11):2555-63.
Antipsychotic drugs and risk of idiopathic venous thromboembolism: a nested case-control study using the
CPRD
Ishiguro, Chieko , Wang, Xi , Li, Lin , Jick, Susan
Pharmacoepidemiology and drug safety. 2014. 23(11):1168-75.
Malaria chemoprophylaxis regimens: A descriptive drug utilization study
Bloechliger, Marlene , Schlagenhauf, Patricia , Toovey, Stephen , Schnetzler, Gabriel , Tatt, Iain , Tomianovic,
Danitza , Jick, Susan S. , Meier, Christoph R.
Travel Medicine and Infectious Disease. 2014. 12(6):718-725.
Comparative benefit of malaria chemoprophylaxis modelled in United Kingdom travellers
Toovey, Stephen , Nieforth, Keith , Smith, Patrick , Schlagenhauf, Patricia , Adamcova, Miriam , Tatt, Iain ,
Tomianovic, Danitza , Schnetzler, Gabriel
Travel Medicine and Infectious Disease. 2014. 12(6):726-732.
Ankylosing spondylitis and risk of ischaemic heart disease: a population-based cohort study
Essers, Ivette , Stolwijk, Carmen , Boonen, Annelies , De Bruin, Marie L , Bazelier, Marloes T , de Vries, Frank
, van Tubergen, Astrid
Ann Rheum Dis 2016 01;75(1):203-9. [Epub released Oct 2014]
Anti-diabetic medications and risk of primary liver cancer in persons with type II diabetes
Hagberg, K W , McGlynn, K A , Sahasrabuddhe, V V , Jick, S
British journal of cancer. 2014. 111(9):1710-7.
Prevalence and incidence rates of cardiovascular, autoimmune, and other diseases in patients with psoriatic or psoriatic arthritis: a retrospective study using Clinical Practice Research Datalink
Edson-Heredia, E , Zhu, B , Lefevre, C , Wang, M , Barrett, A , Bushe, C J , Cox, A , Wu, J J , Maeda-
Chubachi, T
Journal of the European Academy of Dermatology and Venereology : JEADV. 2014. Oct 28, 2014
Continued high rates of antibiotic prescribing to adults with respiratory tract infection: survey of 568 UK general practices
Gulliford, Martin C , Dregan, Alex , Moore, Michael V , Ashworth, Mark , Staa, Tjeerd van , McCann, Gerard ,
Charlton, Judith , Yardley, Lucy , Little, Paul , McDermott, Lisa
BMJ open. 2014. 4(10):e006245.
Effectiveness of maternal pertussis vaccination in England: an observational study
Amirthalingam, Gayatri , Andrews, Nick , Campbell, Helen , Ribeiro, Sonia , Kara, Edna , Donegan, Katherine

52
53
54
55
56
57
58
59
60
61
62
63
64
65
, Fry, Norman K , Miller, Elizabeth , Ramsay, Mary
Lancet. 2014. 384(9953):1521-8.
Causes of death in people with coeliac disease in England compared with the general population: a competing risk analysis
Abdul Sultan, Alyshah , Crooks, Colin J , Card, Tim , Tata, Laila J , Fleming, Kate M , West, Joe
[epub released 2014]
Gut 2015 Aug 01;64(8):1220-1226.
Metformin and low levels of thyroid-stimulating hormone in patients with type 2 diabetes mellitus
Fournier, Jean-Pascal , Yin, Hui , Yu, Oriana Hoi Yun , Azoulay, Laurent
CMAJ. 2014. 186(15):1138-1145.
Estimating the yield of NHS Health Checks in England: a population-based cohort study
Forster, Alice S , Dodhia, Hiten , Booth, Helen , Dregan, Alex , Fuller, Frances , Miller, Jane , Burgess,
Caroline , McDermott, Lisa , Gulliford, Martin C
[epub released 2014]
Journal of public health (Oxford, England) 2015 06;37(2):234-40.
Evaluation of the effectiveness of liraglutide and sitagliptin in type 2 diabetes: a retrospective study in UK primary care
[epub released 2014]
Int J Clin Pract 2015 03;69(3):281-91.
Is cancer associated with polymyalgia rheumatica? A cohort study in the General Practice Research Database
Muller, Sara , Hider, Samantha L , Belcher, John , Helliwell, Toby , Mallen, Christian D
Annals of the rheumatic diseases. 2014. 73(10):1769-73.
Relative risk of myelodysplastic syndromes in patients with autoimmune disorders in the General Practice
Research Database
Wilson, Amanda B , Neogi, Tuhina , Prout, Marianne , Jick, Susan
Cancer epidemiology. 2014. 38(5):544-9.
Association between first-line monotherapy with sulphonylurea versus metformin and risk of all-cause mortality and cardiovascular events: a retrospective, observational study
Morgan, C Ll , Mukherjee, J , Jenkins-Jones, S , Holden, S E , Currie, C J
Diabetes, obesity & metabolism. 2014. 16(10):957-62.
Combination therapy with metformin plus sulphonylureas versus metformin plus DPP-4 inhibitors: association with major adverse cardiovascular events and all-cause mortality
Morgan, C Ll , Mukherjee, J , Jenkins-Jones, S , Holden, S E , Currie, C J
Diabetes, obesity & metabolism. 2014. 16(10):977-83.
Ascertainment of acute liver injury in two European primary care databases
Ruigómez, A , Brauer, R , Rodríguez, L A García , Huerta, C , Requena, G , Gil, M , de Abajo, Francisco ,
Downey, G , Bate, A , Tepie, M Feudjo , de Groot, M , Schlienger, R , Reynolds, R , Klungel, O
European journal of clinical pharmacology. 2014. 70(10):1227-35.
Changes in trends and pattern of strong opioid prescribing in primary care
Zin, C.S. , Chen, L.-C. , Knaggs, R.D.
European Journal of Pain (United Kingdom). 2014. 18(9):1343-1351.
Statin use after colorectal cancer diagnosis and survival: a population-based cohort study
Cardwell, Chris R , Hicks, Blanaid M , Hughes, Carmel , Murray, Liam J
Journal of clinical oncology. 2014. 32(28):3177-83.
Prediction of cardiovascular risk using framingham, ASSIGN and QRISK2: How well do they predict individual rather than population risk?
Van Staa, Tjeerd-Pieter , Gulliford, Martin , Ng, Edmond S.-W. , Goldacre, Ben , Smeeth, Liam
PLoS ONE. 2014. 9(10):.
Pregnancy complications and adverse birth outcomes among women with celiac disease: a population-based study from England
Abdul Sultan, Alyshah , Tata, Laila J , Fleming, Kate M , Crooks, Colin J , Ludvigsson, Jonas F , Dhalwani,
Nafeesa N , Ban, Lu , West, Joe
The American journal of gastroenterology. 2014. 109(10):1653-61.
TSH levels and risk of miscarriage in women on long-term levothyroxine: a community-based study
Taylor, Peter N , Minassian, Caroline , Rehman, Anis , Iqbal, Ahmed , Draman, Mohd Shazli , Hamilton,
William , Dunlop, Diana , Robinson, Anthony , Vaidya, Bijay , Lazarus, John H , Thomas, Sara , Dayan, Colin
M , Okosieme, Onyebuchi E
The Journal of clinical endocrinology and metabolism. 2014. 99(10):3895-902.

66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
Is hormone replacement therapy in post-menopausal women associated with a reduced risk of oesophageal cancer?
Menon, Shyam , Nightingale, Peter , Trudgill, Nigel
United European gastroenterology journal. 2014. 2(5):374-82.
Evolution of medicines and healthcare products regulatory agency
Yao, Li-Xin
Chinese Journal of New Drugs. 2014. 23(18):2132-2143.
The incidence and prevalence of systemic lupus erythematosus in the UK, 1999-2012
Rees, Frances , Doherty, Michael , Grainge, Matthew , Davenport, Graham , Lanyon, Peter , Zhang, Weiya
Ann Rheum Dis 2016 01;75(1):136-41. [ Epub released Sep 2014]
Antibiotic treatment failure in four common infections in UK primary care 1991-2012: longitudinal analysis
Currie, Craig J , Berni, Ellen , Jenkins-Jones, Sara , Poole, Chris D , Ouwens, Mario , Driessen, Stefan , de
Voogd, Hanka , Butler, Christopher C , Morgan, Christopher Ll
BMJ (Clinical research ed.). 2014. 349():g5493.
Trends in incidence and medical resource utilisation in patients with chronic lymphocytic leukaemia: insights from the UK Clinical Practice Research Datalink (CPRD)
Pfeil, A M , Imfeld, P , Pettengell, R , Jick, S S , Szucs, T D , Meier, Christoph R , Schwenkglenks, M
[epub released 2014]
Ann Hematol 2015 03;94(3):421-9.
Risk of vascular events in patients with polymyalgia rheumatica
Hancock, Adam T. , Mallen, Christian D. , Muller, Sara , Belcher, John , Roddy, Edward , Helliwell, Toby ,
Hider, Samantha L.
CMAJ. 2014. 186(13):E495-E501.
Incretin-Based Drugs and the Risk of Congestive Heart Failure
Yu, Oriana Hoi Yun , Filion, Kristian B , Azoulay, Laurent , Patenaude, Valerie , Majdan, Agnieszka , Suissa,
Samy
[epub released 2014]
Diabetes Care 2015 02;38(2):277-84.
Chronic inflammatory disorders and risk of type 2 diabetes mellitus, coronary heart disease, and stroke: a population-based cohort study
Dregan, Alex , Charlton, Judith , Chowienczyk, Phil , Gulliford, Martin C
Circulation. 2014. 130(10):837-44.
Treatment evolution after COPD diagnosis in the UK primary care setting
Wurst, Keele E , Punekar, Yogesh Suresh , Shukla, Amit
PloS one. 2014. 9(9):e105296.
Immortal time bias in observational studies of drug effects in pregnancy
Matok, Ilan , Azoulay, Laurent , Yin, Hui , Suissa, Samy
Birth defects research. Part A, Clinical and molecular teratology. 2014. 100(9):658-62.
Mortality in British hip fracture patients, 2000-2010: A population-based retrospective cohort study
Klop, Corinne , Welsing, Paco M.J. , Cooper, Cyrus , Harvey, Nicholas C. , Elders, Petra J.M. , Bijlsma,
Johannes W.J. , Leufkens, Hubert G.M. , De Vries, Frank
Bone. 2014. 66():171-177.
Predictors and outcomes of increases in creatine phosphokinase concentrations or rhabdomyolysis risk during statin treatment van Staa, Tjeerd P , Carr, Daniel F , O'Meara, Helen , McCann, Gerry , Pirmohamed, Munir
British journal of clinical pharmacology. 2014. 78(3):649-59.
Non-visible versus visible haematuria and bladder cancer risk: A study of electronic records in primary care
Price, Sarah J. , Shephard, Elizabeth A. , Stapley, Sally A. , Barraclough, Kevin , Hamilton, William T.
British Journal of General Practice. 2014. 64(626):e584-e589.
Respiratory pharmacotherapy use in patients newly diagnosed with chronic obstructive pulmonary disease in a primary care setting in the UK: a retrospective cohort study
Wurst, Keele E , Shukla, Amit , Muellerova, Hana , Davis, Kourtney J
COPD. 2014. 11(5):521-30.
Metformin does not affect cancer risk: a cohort study in the U.K. Clinical Practice Research Datalink analyzed like an intention-to-treat trial
Tsilidis, Konstantinos K , Capothanassi, Despoina , Allen, Naomi E , Rizos, Evangelos C , Lopez, David S , van
Veldhoven, Karin , Sacerdote, Carlotta , Ashby, Deborah , Vineis, Paolo , Tzoulaki, Ioanna , Ioannidis, John P

81
82
83
84
85
86
87
88
89
90
91
92
93
94
A
Diabetes care. 2014. 37(9):2522-32.
Incidence of and risk factors for severe hypoglycaemia in treated type 2 diabetes mellitus patients in the UK--a nested case-control analysis
Bruderer, S G , Bodmer, M , Jick, S S , Bader, G , Schlienger, R G , Meier, C R
Diabetes, obesity & metabolism. 2014. 16(9):801-11.
Prevalence and management of chronic kidney disease in primary care patients in the UK
Jameson, K , Jick, S , Hagberg, K W , Ambegaonkar, B , Giles, A , O'Donoghue, D
International journal of clinical practice. 2014. 68(9):1110-21.
Patterns of prescription of antidepressants and antipsychotics across and within pregnancies in a populationbased UK cohort
Margulis, Andrea V , Kang, Elizabeth M , Hammad, Tarek A
Maternal and child health journal. 2014. 18(7):1742-52.
Concurrent use of statins and hormone therapy and risk of venous thromboembolism in postmenopausal women: A population-based case-control study
Fournier, Jean-Pascal , Duijnhoven, Ruben G. , Renoux, Christel , Dell'Aniello, Sophie , Klungel, Olaf H. ,
Suissa, Samy
Menopause. 2014. 21(9):1023-1026.
Epilepsy, diabetes mellitus and accidental injury at work
Palmer, K T , D'Angelo, S , Harris, E C , Linaker, C , Coggon, D
Occupational medicine (Oxford, England). 2014. 64(6):448-53.
Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5·24 million UK adults
Bhaskaran, Krishnan , Douglas, Ian , Forbes, Harriet , dos-Santos-Silva, Isabel , Leon, David A , Smeeth, Liam
Lancet. 2014. 384(9945):755-65.
Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK Clinical
Practice Research Datalink
Clarson, Lorna E , Hider, Samantha L , Belcher, John , Heneghan, Carl , Roddy, Edward , Mallen, Christian D
[epub released 2014]
Ann Rheum Dis 2015 04;74(4):642-7.
Antihyperglycaemic treatment patterns, observed glycaemic control and determinants of treatment change among patients with type 2 diabetes in the United Kingdom primary care: A retrospective cohort study
Maguire, Andrew , Mitchell, Beth D. , Ruzafa, Javier Cid
BMC Endocrine Disorders. 2014. 14(1):.
What is the risk of having a total hip or knee replacement for patients with lupus?
Mukherjee, S , Culliford, D , Arden, N , Edwards, C
[epub released 2014]
Lupus 2015 02;24(2):198-202.
Cardiac glycosides use and the risk of lung cancer: A nested case-control study
Couraud, Se´bastien , Azoulay, Laurent , Dell'Aniello, Sophie , Suissa, Samy
BMC Cancer. 2014. 14(1):.
Incidence of giant cell arteritis and characteristics of patients: Data-driven analysis of comorbidities
Petri, Hans , Nevitt, Alan , Sarsour, Khaled , Napalkov, Pavel , Collinson, Neil
[epub released 2014]
Arthritis care & research 2015 03;67(3):390-5.
Resource Use and Costs up to Two Years Post Diagnosis Among Newly Diagnosed COPD Patients in the UK
Primary Care Setting: A Retrospective Cohort Study
Punekar, Yogesh Suresh , Wurst, Keele , Shukla, Amit
[epub released 2014]
COPD 2015 06;12(3):267-75.
Cardiac glycosides and the risk of breast cancer in women with chronic heart failure and supraventricular arrhythmia
Couraud, Sébastien , Dell'Aniello, Sophie , Bouganim, Nathaniel , Azoulay, Laurent
Breast Cancer Research and Treatment. 2014. 146(3):619-626.
Recognising Kawasaki disease in UK primary care: A descriptive study using the Clinical Practice Research
Datalink
Moore, Abigail , Harnden, Anthony , Mayon-White, Richard
British Journal of General Practice. 2014. 64(625):e477-e483.

95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
Risk of lactic acidosis or elevated lactate concentrations in metformin users with renal impairment: A population-based cohort study
Eppenga, Willemijn L. , Lalmohamed, Arief , Geerts, Arjen F. , Derijks, Hieronymus J. , Wensing, Michel ,
Egberts, Antoine , De Smet, Peter A.G.M. , De Vries, Frank
Diabetes Care. 2014. 37(8):2218-2224.
Incidence of lactic acidosis in patients with type 2 diabetes with and without renal impairment treated with metformin: a retrospective cohort study
Richy, Florent F , Sabidó-Espin, Meritxell , Guedes, Sandra , Corvino, Frank A , Gottwald-Hostalek, Ulrike
Diabetes care. 2014. 37(8):2291-5.
Mortality of patients with multiple sclerosis: a cohort study in UK primary care
Jick, S S , Li, L , Falcone, G J , Vassilev, Z P , Wallander, M-A
Journal of neurology. 2014. 261(8):1508-17.
Retapamulin prescriptions and monitored off-label use
Mundy, Linda M , Sampson, Tim , Logie, John W
Paediatric drugs. 2014. 16(4):331-6.
Measuring persistence to hormonal therapy in patients with breast cancer: Accounting for temporary treatment discontinuation
Huiart, Laetitia , Ferdynus, Cyril , Dell'Aniello, Sophie , Bakiri, Naciba , Giorgi, Roch , Suissa, Samy
Pharmacoepidemiology and Drug Safety. 2014. 23(8):882-889.
Epidemiology of first and recurrent venous thromboembolism: a population-based cohort study in patients without active cancer
Martinez, C , Cohen, A T , Bamber, L , Rietbrock, S
Thrombosis and haemostasis. 2014. 112(2):255-63.
Adverse prognosis of incidentally detected ambulatory atrial fibrillation. A cohort study
Martinez, C , Katholing, A , Freedman, S B
Thrombosis and haemostasis. 2014. 112(2):276-86.
Validation of chronic obstructive pulmonary disease recording in the Clinical Practice Research Datalink
(CPRD-GOLD)
Quint, Jennifer K , Müllerova, Hana , DiSantostefano, Rachael L , Forbes, Harriet , Eaton, Susan , Hurst, John
R , Davis, Kourtney , Smeeth, Liam
BMJ open. 2014. 4(7):e005540.
Initiation of warfarin in patients with atrial fibrillation: early effects on ischaemic strokes
Azoulay, Laurent , Dell'Aniello, Sophie , Simon, Teresa A , Renoux, Christel , Suissa, Samy
European heart journal. 2014. 35(28):1881-7.
Statins and the risk of type 2 diabetes mellitus: Cohort study using the UK clinical practice pesearch datalink
Macedo, Ana F. , Douglas, Ian , Smeeth, Liam , Forbes, Harriet , Ebrahim, Shah
BMC Cardiovascular Disorders. 2014. 14(1):.
Safety of pertussis vaccination in pregnant women in UK: observational study
Donegan, Katherine , King, Bridget , Bryan, Phil
BMJ (Clinical research ed.). 2014. 349():g4219.
Epidemiology of basal cell carcinoma in the United Kingdom: incidence, lifestyle factors, and comorbidities
Reinau, D , Surber, C , Jick, S S , Meier, C R
British journal of cancer. 2014. 111(1):203-6.
Antipsychotic drugs and risks of myocardial infarction: a self-controlled case series study
Brauer, Ruth , Smeeth, Liam , Anaya-Izquierdo, Karim , Timmis, Adam , Denaxas, Spiros C , Farrington, C
Paddy , Whitaker, Heather , Hemingway, Harry , Douglas, Ian
European heart journal. 2014. Jul 8, 2014
Electronic health records for intervention research: a cluster randomized trial to reduce antibiotic prescribing in primary care (eCRT study)
Gulliford, Martin C , van Staa, Tjeerd , Dregan, Alex , McDermott, Lisa , McCann, Gerard , Ashworth, Mark ,
Charlton, Judith , Little, Paul , Moore, Michael V , Yardley, Lucy
Annals of family medicine. 2014. 12(4):344-51.
Association of a reduction in low-density lipoprotein cholesterol with incident cardiovascular and cerebrovascular events among people with type 2 diabetes mellitus
Li, Lin , Ambegaonkar, Baishali M , Reckless, John Pd , Jick, Susan
European Journal of Preventive Cardiology. 2014. 21(7):855-865.
Bone fractures in children with autistic spectrum disorder
Furlano, Raoul I , Bloechliger, Marlene , Jick, Hershel , Meier, Christoph R
Journal of developmental and behavioral pediatrics : JDBP. 2014. 35(6):353-9.

111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
The effect of body mass index on the risk of post-operative complications during the 6 months following total hip replacement or total knee replacement surgery
Wallace, G , Judge, A , Prieto-Alhambra, D , de Vries, F , Arden, N K , Cooper, C
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society. 2014. 22(7):918-27.
The effect of body mass index on the risk of post-operative complications during the 6 months following total hip replacement ortotal knee replacement surgery
Wallace, G. , Judge, A. , Prieto-Alhambra, D. , de Vries, F. , Arden, N.K. , Cooper, C.
Osteoarthritis and Cartilage. 2014. 22(7):918-927.
Risk of fracture in patients with Guillain-Barré syndrome
Pouwels, S. , De Boer, A. , Leufkens, H.G.M. , Weber, W.E.J. , Cooper, C. , Van Staa, T.P. , De Vries, F.
Osteoporosis International. 2014. 25(7):1845-1851.
Point-of-care cluster randomized trial in stroke secondary prevention using electronic health records
Dregan, Alex , Van Staa, Tjeerd P. , McDermott, Lisa , McCann, Gerard , Ashworth, Mark , Charlton, Judith ,
Wolfe, Charles D.A. , Rudd, Anthony , Yardley, Lucy , Gulliford, Martin C.
Stroke. 2014. 45(7):2066-2071.
Antihypertensive drugs and the risk of incident rosacea
Spoendlin, J , Voegel, J J , Jick, S S , Meier, C R
The British journal of dermatology. 2014. 171(1):130-6.
Risk of Acute Appendicitis in and Around Pregnancy: A Population-Based Cohort Study From England
Zingone, Fabiana , Sultan, Alyshah Abdul , Humes, David James , West, Joe
[epub released 2014]
Ann Surg 2015 02;261(2):332-7.
Health care resource utilisation in primary care prior to and after a diagnosis of Alzheimer's disease: a retrospective, matched case-control study in the United Kingdom
Chen, Lei , Reed, Catherine , Happich, Michael , Nyhuis, Allen , Lenox-Smith, Alan
BMC geriatrics. 2014. 14():76.
Potentially inappropriate prescribing among older people in the United Kingdom
Bradley, Marie C , Motterlini, Nicola , Padmanabhan, Shivani , Cahir, Caitriona , Williams, Tim , Fahey, Tom ,
Hughes, Carmel M
BMC geriatrics. 2014. 14():72.
Cluster randomized trials utilizing primary care electronic health records: Methodological issues in design, conduct, and analysis (eCRT Study)
Gulliford, Martin C. , van Staa, Tjeerd P. , McDermott, Lisa , McCann, Gerard , Charlton, Judith , Dregan, Alex
, Ashworth, Mark , Wolfe, Charles , Rudd, Anthony , Yardley, Lucy , Little, Paul , Moore, Michael V.
Trials. 2014. 15(1):.
Semi Automated Transformation to OWL Formatted Files as an Approach to Data Integration. A Feasibility
Study Using Environmental, Disease Register and Primary Care Clinical Data
Liang, S F , Taweel, A , Miles, S , Kovalchuk, Y , Spiridou, A , Barratt, B , Hoang, U , Crichton, S , Delaney, B
C , Wolfe, C
[epub released 2014]
Methods Inf Med 2015;54(1):32-40.
Risk of stroke following herpes zoster: a self-controlled case-series study
Langan, Sinéad M , Minassian, Caroline , Smeeth, Liam , Thomas, Sara L
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2014.
58(11):1497-503.
How many people inject insulin? UK estimates from 1991 to 2010
Holden, S E , Gale, E A M , Jenkins-Jones, S , Currie, C J
Diabetes, obesity & metabolism. 2014. 16(6):553-9.
Smoking cessation interventions following acute coronary syndrome: A missed opportunity?
Boggon, Rachael , Timmis, Adam , Hemingway, Harry , Raju, Sunil , Malvestiti, Franco Mondello , Van Staa,
Tjeerd P.
European Journal of Preventive Cardiology. 2014. 21(6):767-773.
High-potency statin and ezetimibe use and mortality in survivors of an acute myocardial infarction: A population-based study
Pauriah, Maheshwar , Elder, Douglas H.J. , Ogston, Simon , Noman, Awsan Y.S. , Majeed, Azeem , Wyatt,
Jeremy C. , Choy, Anna-Maria , MacDonald, Thomas M. , Struthers, Allan D. , Lang, Chim C.
Heart. 2014. 100(11):867-872.
0066 Problems of vision, hearing and balance and risks of workplace injury
Palmer, Keith , D'Angelo, Stefania , Clare Harris, E , Linaker, Cathy , Coggon, David
Occupational and environmental medicine. 2014. 71 Suppl 1():A7.

126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
The PROTECCT-M study: A cohort study investigating associations between novel specific biomarkers, patient-related, healthcare system markers and the trajectory of COPD patients treated in primary care
Søndergaard, Jens , Halling, Anders
BMC Pulmonary Medicine. 2014. 14(1):.
Quantification of risk factors for herpes zoster: population based case-control study
Forbes, Harriet J , Bhaskaran, Krishnan , Thomas, Sara L , Smeeth, Liam , Clayton, Tim , Langan, Sinéad M
BMJ (Clinical research ed.). 2014. 348():g2911.
Text messaging reminders for influenza vaccine in primary care: protocol for a cluster randomised controlled trial (TXT4FLUJAB)
Herrett, Emily , van Staa, Tjeerd , Free, Caroline , Smeeth, Liam
BMJ open. 2014. 4(5):e004633.
Incidence and prevalence of celiac disease and dermatitis herpetiformis in the UK over two decades:
Population-based study
West, Joe , Fleming, Kate M. , Tata, Laila J. , Card, Timothy R. , Crooks, Colin J.
American Journal of Gastroenterology. 2014. 109(5):757-768.
Electronic health records for biological sample collection: feasibility study of statin-induced myopathy using the Clinical Practice Research Datalink
O'Meara, Helen , Carr, Daniel F , Evely, Jane , Hobbs, Mark , McCann, Gerard , van Staa, Tjeerd ,
Pirmohamed, Munir
British journal of clinical pharmacology. 2014. 77(5):831-8.
Increased risk of subsequent myocardial infarction in patients with type 2 diabetes: A retrospective cohort study using the U.K. general practice research database
Liang, Huifang , Vallarino, Carlos , Joseph, Guiandre , Manne, Sudhakar , Perez, Alfonso , Zhang, Shumin
Diabetes Care. 2014. 37(5):1329-1337.
New estimates of the burden of acute community-acquired infections among older people with diabetes mellitus: A retrospective cohort study using linked electronic health records
Mcdonald, H.I. , Nitsch, D. , Millett, E.R.C. , Sinclair, A. , Thomas, S.L.
Diabetic Medicine. 2014. 31(5):606-614.
The effect of withdrawal of rosiglitazone on treatment pathways, diabetes control and patient outcomes: A retrospective cohort study
Morgan, Christopher Ll. , Puelles, Jorge , Poole, Chris D. , Currie, Craig J.
Journal of Diabetes and its Complications. 2014. 28(3):360-364.
Variation in the risk of venous thromboembolism in people with colorectal cancer: A population-based cohort study from England
Walker, A.J. , West, J. , Card, T.R. , Humes, D.J. , Grainge, M.J.
Journal of Thrombosis and Haemostasis. 2014. 12(5):641-649.
The role of mental health problems and common psychotropic drug treatments in accidental injury at work: a case-control study
Palmer, Keith T , D'Angelo, Stefania , Harris, E Clare , Linaker, Cathy , Coggon, David
Occupational and environmental medicine. 2014. 71(5):308-12.
Injury among children and young adults with epilepsy
Prasad, Vibhore , Kendrick, Denise , Sayal, Kapil , Thomas, Sara L , West, Joe
Pediatrics. 2014. 133(5):827-35.
Impact and cost-effectiveness of a universal strategy to promote physical activity in primary care: populationbased cohort study and Markov model
Gulliford, Martin C , Charlton, Judith , Bhattarai, Nawaraj , Charlton, Christopher , Rudisill, Caroline
The European journal of health economics : HEPAC : health economics in prevention and care. 2014.
15(4):341-51.
Incretin based drugs and risk of acute pancreatitis in patients with type 2 diabetes: Cohort study
Faillie, Jean-Luc , Azoulay, Laurent , Patenaude, Valerie , Hillaire-Buys, Dominique , Suissa, Samy
BMJ (Online). 2014. 348():.
Can analyses of electronic patient records be independently and externally validated? The effect of statins on the mortality of patients with ischaemic heart disease: a cohort study with nested case-control analysis
Reeves, David , Springate, David A , Ashcroft, Darren M , Ryan, Ronan , Doran, Tim , Morris, Richard , Olier,
Ivan , Kontopantelis, Evangelos
BMJ open. 2014. 4(4):e004952.
Validating childhood asthma in an epidemiological study using linked electronic patient records
Cornish, Rosaleen P , Henderson, John , Boyd, Andrew W , Granell, Raquel , Van Staa, Tjeerd , Macleod, John
BMJ open. 2014. 4(4):e005345.

141
142
143
144
145
146
147
148
149
150
151
152
153
154
Post-diagnostic prescriptions for low-dose aspirin and breast cancer-specific survival: A nested case-control study in a breast cancer cohort from the UK Clinical Practice
Murray, Liam J. , Cooper, Janine A. , Hughes, Carmel M. , Powe, Des G. , Cardwell, Chris R.
Breast Cancer Research. 2014. 16(2):.
Poorly controlled type 2 diabetes mellitus is associated with a decreased risk of incident gout: a populationbased case-control study
Bruderer, Saskia G , Bodmer, Michael , Jick, Susan S , Meier, Christoph R
[epub released 2014]
Ann Rheum Dis 2015 09;74(9):1651-8.
Switching patients from other inhaled corticosteroid devices to the Easyhaler(®): historical, matched-cohort study of real-life asthma patients
Price, David , Thomas, Vicky , von Ziegenweidt, Julie , Gould, Shuna , Hutton, Catherine , King, Christine
Journal of asthma and allergy. 2014. 7():31-51.
Exposure to combined oral contraceptives and risk of venous thromboembolism: a protocol for nested casecontrol studies using the QResearch and the CPRD databases
Vinogradova, Yana , Coupland, Carol , Hippisley-Cox, Julia
BMJ open. 2014. 4(4):e004499.
Post-diagnostic prescriptions for low-dose aspirin and breast cancer-specific survival: a nested case-control study in a breast cancer cohort from the UK Clinical Practice Research Datalink
Murray, Liam J , Cooper, Janine A , Hughes, Carmel M , Powe, Des G , Cardwell, Chris R
Breast cancer research : BCR. 2014. 16(2):R34.
Obesity paradox in people newly diagnosed with type 2 diabetes with and without prior cardiovascular disease
Thomas, G , Khunti, K , Curcin, V , Molokhia, M , Millett, C , Majeed, A , Paul, S
Diabetes, obesity & metabolism. 2014. 16(4):317-25.
Proton pump inhibitors and the risk of hospitalisation for community-acquired pneumonia: Replicated cohort studies with meta-analysis
Filion, Kristian B. , Chateau, Dan , Targownik, Laura E. , Gershon, Andrea , Durand, Madeleine , Tamim, Hala
, Teare, Gary F. , Ravani, Pietro , Ernst, Pierre , Dormuth, Colin R.
Gut. 2014. 63(4):552-558.
A comparison of psychotropic medication prescribing patterns in East of England prisons and the general population
Hassan, Lamiece , Senior, Jane , Frisher, Martin , Edge, Dawn , Shaw, Jenny
Journal of Psychopharmacology. 2014. 28(4):357-362.
The risk of venous thromboembolism in patients with multiple sclerosis: the Clinical Practice Research
Datalink
Peeters, P J H L , Bazelier, M T , Uitdehaag, B M J , Leufkens, H G M , De Bruin, M L , de Vries, F
Journal of thrombosis and haemostasis : JTH. 2014. 12(4):444-51.
Elevated risk of clinical fractures and associated risk factors in patients with systemic lupus erythematosus versus matched controls: a population-based study in the United Kingdom
Bultink, I E M , Harvey, N C , Lalmohamed, A , Cooper, C , Lems, W F , van Staa, T P , de Vries, F
Osteoporosis international : a journal established as result of cooperation between the European Foundation for
Osteoporosis and the National Osteoporosis Foundation of the USA. 2014. 25(4):1275-83.
Risk of acute myocardial infarction, stroke, or death in patients initiating olmesartan or other angiotensin receptor blockers - a cohort study using the clinical practice research datalink
Zhou, Esther H. , Gelperin, Kate , Levenson, Mark S. , Rose, Martin , Hsueh, Ya-Hui , Graham, David J.
Pharmacoepidemiology and Drug Safety. 2014. 23(4):340-347.
Atypical antipsychotics and hyperglycemic emergencies: multicentre, retrospective cohort study of administrative data
Lipscombe, Lorraine L , Austin, Peter C , Alessi-Severini, Silvia , Blackburn, David F , Blais, Lucie , Bresee,
Lauren , Filion, Kristian B , Kawasumi, Yuko , Kurdyak, Paul , Platt, Robert W , Tamim, Hala , Paterson, J
Michael
Schizophrenia research. 2014. 154(1-3):54-60.
The association between psychiatric diseases, psychotropic drugs and the risk of incident rosacea
Spoendlin, J , Bichsel, F , Voegel, J J , Jick, S S , Meier, C R
The British journal of dermatology. 2014. 170(4):878-83.
Beta-blocker usage after malignant melanoma diagnosis and survival: a population-based nested case-control study
McCourt, C , Coleman, H G , Murray, L J , Cantwell, M M , Dolan, O , Powe, D G , Cardwell, C R
The British journal of dermatology. 2014. 170(4):930-8.

155
156
157
158
159
160
161
162
163
164
165
166
167
168
Opportunities to diagnose chronic obstructive pulmonary disease in routine care in the UK: a retrospective study of a clinical cohort
Jones, Rupert C M , Price, David , Ryan, Dermot , Sims, Erika J , von Ziegenweidt, Julie , Mascarenhas,
Laurence , Burden, Anne , Halpin, David M G , Winter, Robert , Hill, Sue , Kearney, Matt , Holton, Kevin ,
Moger, Anne , Freeman, Daryl , Chisholm, Alison , Bateman, Eric D
The Lancet. Respiratory medicine. 2014. 2(4):267-76.
Renal failure in lithium-treated bipolar disorder: A retrospective cohort study
Close, Helen , Reilly, Joe , Mason, James M. , Kripalani, Mukesh , Wilson, Douglas , Main, John , Hungin, A.
Pali S.
PLoS ONE. 2014. 9(3):.
The epidemiology of extra-articular manifestations in ankylosing spondylitis: a population-based matched cohort study
Stolwijk, Carmen , Essers, Ivette , van Tubergen, Astrid , Boonen, Annelies , Bazelier, Marloes T , De Bruin,
Marie L , de Vries, Frank
[epub released 2014]
Ann Rheum Dis 2015 Jul 01;74(7):1373-1378.
Effect of anxiolytic and hypnotic drug prescriptions on mortality hazards: retrospective cohort study
Weich, Scott , Pearce, Hannah Louise , Croft, Peter , Singh, Swaran , Crome, Ilana , Bashford, James , Frisher,
Martin
BMJ (Clinical research ed.). 2014. 348():g1996.
Influenza and pneumococcal vaccination and risk of stroke or transient ischaemic attack-Matched case control study
Siriwardena, A. Niroshan , Asghar, Zahid , Coupland, Carol C.A.
Vaccine. 2014. 32(12):1354-1361.
Type 2 diabetes and the risk of mortality among patients with prostate cancer
Bensimon, Leah , Yin, Hui , Suissa, Samy , Pollak, Michael N , Azoulay, Laurent
Cancer causes & control : CCC. 2014. 25(3):329-38.
Pregnancy losses in women with type 1 or type 2 diabetes in the UK: An investigation using primary care records
Mcgrogan, A. , Snowball, J. , de Vries, C.S.
Diabetic Medicine. 2014. 31(3):357-365.
Statin use is associated with reduced risk of histologic subtypes of esophageal cancer: A nested case-control analysis
Alexandre, Leo , Clark, Allan B. , Bhutta, Hina Y. , Holt, Sean , Lewis, Michael P.N. , Hart, Andrew R.
Gastroenterology. 2014. 146(3):661-668.
Low-dose aspirin use after diagnosis of colorectal cancer does not increase survival: A case-control analysis of a population-based cohort
Cardwell, Chris R. , Kunzmann, Andrew T. , Cantwell, Marie M. , Hughes, Carmel , Baron, John A. , Powe,
Des G. , Murray, Liam J.
Gastroenterology. 2014. 146(3):700-708.e2.
Exploiting the potential of large databases of electronic health records for research using rapid search algorithms and an intuitive query interface
Tate, A Rosemary , Beloff, Natalia , Al-Radwan, Balques , Wickson, Joss , Puri, Shivani , Williams, Timothy ,
Van Staa, Tjeerd , Bleach, Adrian
Journal of the American Medical Informatics Association : JAMIA. 2014. 21(2):292-8.
Drugs affecting the renin-angiotensin system and survival from cancer: A population based study of breast, colorectal and prostate cancer patient cohorts
Cardwell, Chris R. , Mc Menamin, Úna C. , Hicks, Blánaid M. , Hughes, Carmel , Cantwell, Marie M. , Murray,
Liam J.
BMC Medicine. 2014. 12(1):.
Comparison of cancer diagnostic intervals before and after implementation of NICE guidelines: analysis of data from the UK General Practice Research Database
Neal, R D , Din, N U , Hamilton, W , Ukoumunne, O C , Carter, B , Stapley, S , Rubin, G
British journal of cancer. 2014. 110(3):584-92.
Comparison of cancer diagnostic intervals before and after implementation of NICE guidelines: Analysis of data from the GBR General Practice Research Database
Neal, R.D. , Din, N.U. , Hamilton, W. , GBRoumunne, O.C. , Carter, B. , Stapley, S. , Rubin, G.
British Journal of Cancer. 2014. 110(3):584-592.
Cost-effectiveness of a universal strategy of brief dietary intervention for primary prevention in primary care:
Population-based cohort study and Markov model

169
170
171
172
173
174
175
176
177
178
179
180
181
182
Gulliford, Martin C. , Bhattarai, Nawaraj , Charlton, Judith , Rudisill, Caroline
Cost Effectiveness and Resource Allocation. 2014. 12(1):.
Diagnosis of liver cirrhosis in England, a cohort study, 1998-2009: A comparison with cancer
Ratib, Sonia , West, Joe , Crooks, Colin J. , Fleming, Kate M.
American Journal of Gastroenterology. 2014. 109(2):190-198.
The association of vitamin D supplementation with the risk of cancer in postmenopausal women
Redaniel, Maria Theresa , Gardner, Michael P , Martin, Richard M , Jeffreys, Mona
Cancer causes & control : CCC. 2014. 25(2):267-71.
External validation of the UKPDS risk engine in incident type 2 diabetes: A need for new type 2 diabetesspecific risk equations
Bannister, Christian A. , Poole, Chris D. , Jenkins-Jones, Sara , Ll. Morgan, Christopher , Elwyn, Glyn , Spasíc,
Irena , Currie, Craig J.
Diabetes Care. 2014. 37(2):537-545.
General practice-recorded depression and antidepressant use in young people with newly diagnosed Type 1 diabetes: A cohort study using the Clinical Practice Research Datalink
Morgan, E. , Patterson, C.C. , Cardwell, C.R.
Diabetic Medicine. 2014. 31(2):241-245.
Impact of body mass index on prevalence of multimorbidity in primary care: Cohort study
Booth, Helen P. , Prevost, A Toby , Gulliford, Martin C.
Family Practice. 2014. 31(1):38-43.
Atrial fibrillation: Improvement in identification and stroke preventive therapy - Data from the UK Clinical
Practice Research Datalink, 2000-2012
Scowcroft, A.C.E. , Cowie, M.R.
International Journal of Cardiology. 2014. 171(2):169-173.
1 and 5 year survival estimates for people with cirrhosis of the liver in England, 1998-2009: A large population study
Ratib, Sonia , Fleming, Kate M. , Crooks, Colin J. , Aithal, Guruprasad P. , West, Joe
Journal of Hepatology. 2014. 60(2):282-289.
Angiotensin-converting enzyme inhibitor therapy and colorectal cancer risk
Makar, George A. , Holmes, John H. , Yang, Yu-Xiao
Journal of the National Cancer Institute. 2014. 106(2):.
Risk of fracture in patients with muscular dystrophies
Pouwels, S , de Boer, A , Leufkens, H G M , Weber, W E J , Cooper, C , van Onzenoort, H A W , de Vries, F
Osteoporosis international : a journal established as result of cooperation between the European Foundation for
Osteoporosis and the National Osteoporosis Foundation of the USA. 2014. 25(2):509-18.
Ischaemic cardiac events and use of strontium ranelate in postmenopausal osteoporosis: A nested case-control study in the CPRD
Cooper, C. , Fox, K.M. , Borer, J.S.
Osteoporosis International. 2014. 25(2):737-745.
Withdrawing performance indicators: retrospective analysis of general practice performance under UK Quality and Outcomes Framework
Kontopantelis, Evangelos , Springate, David , Reeves, David , Ashcroft, Darren M , Valderas, Jose M , Doran,
Tim
BMJ (Clinical research ed.). 2014. 348():g330.
Population-based cohort study of warfarin-treated patients with atrial fibrillation: incidence of cardiovascular and bleeding outcomes
Gallagher, Arlene M , van Staa, Tjeerd P , Murray-Thomas, Tarita , Schoof, Nils , Clemens, Andreas ,
Ackermann, Diana , Bartels, Dorothee B
BMJ open. 2014. 4(1):e003839.
Managing cancer pain at the end of life with multiple strong opioids: A population-based retrospective cohort study in primary care
Gao, Wei , Gulliford, Martin , Bennett, Michael I. , Murtagh, Fliss E. M. , Higginson, Irene J.
PLoS ONE. 2014. 9(1):.
Hormone replacement therapy and mid-term implant survival following knee or hip arthroplasty for osteoarthritis: a population-based cohort study
Prieto-Alhambra D, Javaid MK, Judge A, Maskell J, Cooper C, Arden NK, Mullee M, Rafferty J, Carr
A, Price A, Javaid K, Beard D, Altman D, Clarke N.
[epub released 2014]
Ann Rheum Dis 2015 Mar 01;74(3):557-563.

183
184
185
186
187
188
189
190
191
192
193
Rising burden of gout in the UK but continuing suboptimal management: a nationwide population study
Kuo, Chang-Fu , Grainge, Matthew J , Mallen, Christian , Zhang, Weiya , Doherty, Michael
[epub released 2014]
Ann Rheum Dis 2015 04;74(4):661-7.
Prevalence and burden of breathlessness in patients with chronic obstructive pulmonary disease managed in primary care
Müllerová, Hana , Lu, Chao , Li, Hao , Tabberer, Maggie
PLoS ONE. 2014. 9(1):.
COPD management costs according to the frequency of COPD exacerbations in UK primary care
Punekar, Yogesh Suresh , Shukla, Amit , Müllerova, Hana
International Journal of COPD. 2014. 9():65-73.
Use of diuretics and risk of incident gout: a population-based case-control study
Bruderer, Saskia , Bodmer, Michael , Jick, Susan S , Meier, Christoph R
Arthritis & rheumatology (Hoboken, N.J.). 2014. 66(1):185-196.
Low-dose aspirin and survival in men with prostate cancer: a study using the UK Clinical Practice Research
Datalink
Cardwell, Chris R , Flahavan, Evelyn M , Hughes, Carmel M , Coleman, Helen G , O'Sullivan, Joe M , Powe,
Des G , Murray, Liam J
Cancer causes & control : CCC. 2014. 25(1):33-43.
Rates and risk of hospitalisation among patients with type 2 diabetes: Retrospective cohort study using the UK
General Practice Research Database linked to English Hospital Episode Statistics
Khalid, J.M. , Raluy-Callado, M. , Curtis, B.H. , Boye, K.S. , Maguire, A. , Reaney, M.
International Journal of Clinical Practice. 2014. 68(1):40-48.
Falling threshold for treatment of borderline elevated thyrotropin levels-balancing benefits and risks: evidence from a large community-based study
Taylor, Peter N , Iqbal, Ahmed , Minassian, Caroline , Sayers, Adrian , Draman, Mohd S , Greenwood,
Rosemary , Hamilton, William , Okosieme, Onyebuchi , Panicker, Vijay , Thomas, Sara L , Dayan, Colin
JAMA internal medicine. 2014. 174(1):32-9.
Incidence and prevalence of multiple sclerosis in the UK 1990-2010: a descriptive study in the General Practice
Research Database
Mackenzie, I S , Morant, S V , Bloomfield, G A , MacDonald, T M , O'Riordan, J
Journal of neurology, neurosurgery, and psychiatry. 2014. 85(1):76-84.
The Clinical Practice Research Datalink for drug safety in pregnancy research: an overview
Charlton, Rachel , Snowball, Julia , Sammon, Cormac , de Vries, Corinne
Thérapie. 2014. 69(1):83-9.
Adverse prognosis of incidentally detected ambulatory atrial fibrillation
Martinez, Carlos , Katholing, Anja , Freedman, Saul Benedict
Thrombosis and Haemostasis. 2014. 112(2):276-286.
Use of anti-malarial drugs and the risk of developing eye disorders
Schneider, Cornelia , Adamcova, Miriam , Jick, Susan S. , Schlagenhauf, Patricia , Miller, Mary K. , Rhein,
Hans-Georg , Meier, Christoph R.
Travel Medicine and Infectious Disease. 2014. 12(1):40-47.
1.
2.
3.
Lower respiratory tract infection in the first year of life is associated with worse lung function in adult life: Prospective results from the Barry Caerphilly Growth study.
Lopez Bernal JA, Upton MN, Henderson AJ, Dedman D, McCarthy A, Davey Smith G, Ben-Shlomo Y.
Ann Epidemiol 2013 07;23(7):422-427.
Risk of mortality (including sudden cardiac death) and major cardiovascular events in users of olanzapine and other antipsychotics: A study with the general practice research database.
Jones ME, Campbell G, Patel D, Brunner E, Shatapathy CC, Murray-Thomas T, Van Staa TP, Motsko
S.
Cardiovascular Psychiatry and Neurology 2013;2013.
The use of metformin and the incidence of lung cancer in patients with type 2 diabetes.
Smiechowski BB, Azoulay L, Yin H, Pollak MN, Suissa S.
Diabetes Care. 2013 Jan;36(1):124-9.

4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
PMID:22923670
Temporal trends of Barrett's oesophagus and gastro-oesophageal reflux and related oesophageal cancer over a 10-year period in England and Wales and associated proton pump inhibitor and H2RA prescriptions: a GPRD study.
Alexandropoulou K, van Vlymen J, Reid F, Poullis A, Kang JY.
Eur J Gastroenterol Hepatol. 2013 Jan;25(1):15-21.
PMID: 23022985.
Thromboprophylaxis of elderly patients with AF in the UK: an analysis using the General Practice
Research Database (GPRD) 2000-2009.
Scowcroft AC, Lee S, Mant J.
Heart. 2013 Jan;99(2):127-32.
PMID: 23086966.
A study of baseline prevalence and cumulative incidence of comorbidity and extra-articular manifestations in RA and their impact on outcome.
Norton S, Koduri G, Nikiphorou E, Dixey J, Williams P, Young A.
Rheumatology (Oxford). 2013 Jan;52(1):99-110.
PMID: 23086517.
Costs Associated With Treatment of Chronic Low Back Pain: An Analysis of the UK General Practice
Research Database.
Hong J, Reed C, Novick D, Happich M
Spine (Phila Pa 1976). 2013 Jan 1;38(1):75-82.
PMID: 23038621.
The concurrent use of antithrombotic therapies and the risk of bleeding in patients with atrial fibrillation
Azoulay L, Dell'Aniello S, Simon T, Renoux C, Suissa S..
Thromb Haemost. 2013 Mar 5;109(3):431-9.
PMID: 23306435.
Health care costs before and after diagnosis of depression in patients with unexplained pain: a retrospective cohort study using the United Kingdom General Practice Research Database.
Reed C, Hong J, Novick D, Lenox-Smith A, Happich M.
Clinicoecon Outcomes Res. 2013;5:37-47.
PMID: 23355787
Opioids and risk of type 2 diabetes in adults with non-cancer pain
Li L, Setoguchi S, Cabral H, Jick S.
Pain Physician. 2013 Jan;16(1):77-88.
PMID:23340536.
Risk of childhood cancer with symptoms in primary care: a population-based case-control study.
Dommett RM, Redaniel T, Stevens MC, Martin RM, Hamilton W. Br J
Gen Pract. 2013 Jan;63(606):e22-9.
PMID:23336454
Exposure to bisphosphonates and risk of gastrointestinal cancers: series of nested case-control studies with QResearch and CPRD data .
Vinogradova Y, Coupland C, Hippisley-Cox J
BMJ. 2013 Jan 16;346:f114.
PMID: 23325866
Concurrent use of diuretics, angiotensin converting enzyme inhibitors, and angiotensin receptor blockers with non-steroidal anti-inflammatory drugs and risk of acute kidney injury: nested case-control study.
Lapi F, Azoulay L, Yin H, Nessim SJ, Suissa S.
BMJ. 2013 Jan 8;346:e8525.

14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
PMID: 23299844
Impact of UK Medical Eligibility Criteria implementation on prescribing of combined hormonal contraceptives
Briggs PE, Praet CA, Humphreys SC, Zhao C.. J Fam
J Fam Plann Reprod Health Care. 2013 Jul;39(3):190-6
PMID: 23299629.
Trends in the prevalence of antipsychotic drug use among patients with Alzheimer's disease and other dementias including those treated with antidementia drugs in the community in the UK: a cohort study.
Martinez C, Jones RW, Rietbrock S
BMJ Open. 2013 Jan 7;3(1).
PubMed PMID: 23299113
The patterns of anticoagulation control and the risk of stroke, bleeding and mortality in patients with non-valvular atrial fibrillation.
Van Den Ham HA, Klungel OH, Leufkens HG, Van Staa TP
J Thromb Haemost. 2013 Jan;11(1):107-15
PMID: 23088617.
Associations of angiotensin targeting antihypertensive drugs with mortality and hospitalization in primary care patients with dementia.
Kehoe PG, Davies NM, Martin RM, Ben-Shlomo Y. J
Alzheimers Dis. 2013;33(4):999-1008.
PMID: 23076074.
Smoking cessation interventions following acute coronary syndrome: a missed opportunity?
Boggon R, Timmis A, Hemingway H, Raju S, Mondello Malvestiti F, Van Staa TP.
Eur J Prev Cardiol. 2013 Jan 10. [Epub ahead of print]
PMID: 22952289.
The risk of adverse outcomes in association with use of testosterone products: a cohort study using the
UK-based general practice research database.
Jick SS, Hagberg KW.
Br J Clin Pharmacol. 2013 Jan;75(1):260-70.
PMID: 22574772
Pioglitazone and bladder cancer: a propensity score matched cohort study.
Wei L, MacDonald TM, Mackenzie IS.
Br J Clin Pharmacol. 2013 Jan;75(1):254-9.
PMID: 22574756
Epidemiology, Co-Morbidities, and Medication Use of Patients with Alzheimer's Disease or Vascular
Dementia in the UK.
Imfeld P, Brauchli Pernus YB, Jick SS, Meier CR.
J Alzheimers Dis. 2013 Jan 1;35(3):565-73.
PMID: 23455986.
Oral bisphosphonates are associated with increased risk of subtrochanteric and diaphyseal fractures in elderly women: a nested case-control study.
Erviti J, Alonso A, Oliva B, Gorricho J, López A, Timoner J, Huerta C, Gil M, De Abajo F.
BMJ Open. 2013 Jan 30;3(1).
PMID: 23370011
Pandemic influenza vaccination during pregnancy: An investigation of vaccine uptake during the
2009/10 pandemic vaccination campaign in Great Britain
Sammon CJ, McGrogan A, Snowball J, de Vries CS..
Hum Vaccin Immunother. 2013 Jan 30;9(4).
PMID: 23364304.

24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
Mortality and other important diabetes-related outcomes with insulin vs other antihyperglycemic therapies in type 2 diabetes.
Currie CJ, Poole CD, Evans M, Peters JR, Morgan CL.
J Clin Endocrinol Metab. 2013 Feb;98(2):668-77.
PMID: 23372169
Risk of fracture with thiazolidinediones: an individual patient data meta-analysis.
Bazelier MT, de Vries F, Vestergaard P, Herings RM, Gallagher AM, Leufkens
HG, van Staa TP.
Front Endocrinol (Lausanne). 2013;4:11.
PMID: 23549934
Optimising use of electronic health records to describe the presentation of rheumatoid arthritis in primary care: a strategy for developing code lists.
Nicholson A, Ford E, Davies KA, Smith HE, Rait G, Tate AR, Petersen I, Cassell J
PLoS One. 2013;8(2):e54878. Epub 2013 Feb 22.
PMID: 23451024
Asthma drugs and the risk of congenital anomalies.
Vasilakis-Scaramozza C, Aschengrau A, Cabral HJ, Jick SS.
Pharmacotherapy. 2013 Apr;33(4):363-8.
PMID: 23450814.
An observational descriptive study of the epidemiology and treatment of neuropathic pain in a UK general population.
Hall GC, Morant SV, Carroll D, Gabriel ZL, McQuay HJ.
BMC Fam Pract. 2013 Feb 26;14:28.
PMID: 23442783
All-Cause and Cardiovascular Mortality in Middle-Aged People With Type 2 Diabetes Compared With
People Without Diabetes in a Large U.K. Primary Care Database.
Taylor KS, Heneghan CJ, Farmer AJ, Fuller AM, Adler AI, Aronson JK, Stevens RJ.
Diabetes Care. 2013 Aug;36(8):2366-71
PMID: 23435157.
The association between Parkinson's disease and anti-epilepsy drug carbamazepine: a case-control study using the UK General Practice Research Database.
Skow A, Douglas I, Smeeth L.
Br J Clin Pharmacol. 2013 Feb 21. [Epub ahead of print]
PMID: 23432592.
Oral bisphosphonates may not decrease hip fracture risk in elderly Spanish women: a nested case-control study.
Erviti J, Alonso A, Gorricho J, López A
BMJ Open. 2013 Feb 20;3(2).
PMID: 23430594
Risk of fracture in patients with Parkinson's disease.
Pouwels S, Bazelier MT, de Boer A, Weber WE, Neef C, Cooper C, de Vries F.
Osteoporos Int. 2013 Aug;24(8):2283-90
PMID: 23430103.
Incidence of bone metastases in breast cancer patients in the United Kingdom: results of a multi-database linkage study using the general practice research database.
Hagberg KW, Taylor A, Hernandez RK, Jick S.
Cancer Epidemiol. 2013 Jun;37(3):240-6.
PMID:23416031.
Opioid use for noncancer pain and risk of myocardial infarction amongst adults.
Li L, Setoguchi S, Cabral H, Jick S.

35.
36.
37.
38.
39.
40.
J Intern Med. 2013 May;273(5):511-26.
PMID: 23331508.
Incidence of prostate, breast, lung and colorectal cancer following new consultation for musculoskeletal pain: A cohort study among UK primary care patients.
Jordan KP, Hayward RA, Blagojevic-Bucknall M, Croft P.
Int J Cancer. 2013 Aug 1;133(3):713-20
PMID: 23354595.
Association of infant pneumococcal vaccination with pneumococcal pneumonia among mothers: a nested case-control study using the GPRD.
Hak E, Shea KM, Jick SS.
Vaccine. 2013 Mar 15;31(12):1590-6.
PMID: 23357195.
Use of Depot Medroxyprogesterone Acetate Contraception and Incidence of Bone Fracture.
Lanza LL, McQuay LJ, Rothman KJ, Bone HG, Kaunitz AM, Harel Z, Ataher Q, Ross D, Arena PL, Wolter KD.
Obstet Gynecol. 2013 Mar;121(3):593-600.
PMID: 23635623.
Primary biliary cirrhosis does not increase the risk of UTIs following diagnosis compared to other chronic liver diseases?
Varyani FK, West J, Card TR.
Liver t. 2013 Mar;33(3):384-8.
PMID: 23402609.
Metformin and the risk of endometrial cancer: A case-control analysis.
Becker C, Jick SS, Meier CR, Bodmer M.
Gynecol Oncol. 2013 Jun;129(3):565-9
PMID: 23523618
An inventory of European data sources for the long-term safety evaluation of methylphenidate.
Murray ML, Insuk S, Banaschewski T, Neubert AC, McCarthy S, Buitelaar JK,
Coghill D, Dittmann RW, Konrad K, Panei P, Rosenthal E, Sonuga-Barke EJ, Wong IC.
Eur Child Adolesc Psychiatry. 2013 Mar 19. [Epub ahead of print]
PubMed PMID: 23508655.
41.
42.
Prevalence of adult Huntington's disease in the UK based on diagnoses recorded in general practice records.
Evans SJ, Douglas I, Rawlins MD, Wexler NS, Tabrizi SJ, Smeeth L.
J Neurol Neurosurg Psychiatry. 2013 Mar 29. [Epub ahead of print]
PubMed PMID: 23482661.
The UK National Health Service: delivering equitable treatment across the spectrum of coronary disease.
Hawkins NM, Scholes S, Bajekal M, Love H, O'Flaherty M, Raine R, Capewell S.
Circ Cardiovasc Qual Outcomes. 2013 Mar 1;6(2):208-16.
PMID: 23481523.
43.
44.
Statin Use and Clinical Osteoarthritis in the General Population: A Longitudinal Study .
Kadam UT, Blagojevic M, Belcher J.
J Gen Intern Med. 2013 Jul;28(7):943-9
PubMed PMID: 23471638.
Association of a reduction in low-density lipoprotein cholesterol with incident cardiovascular and cerebrovascular events among people with type 2 diabetes mellitus
Li L, Ambegaonkar BM, Reckless JP, Jick S..
Eur J Prev Cardiol. 2013 Mar 4. [Epub ahead of print]
PubMed PMID: 23460659.
45. Antimalarial chemoprophylaxis and the risk of neuropsychiatric disorders.

46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
Schneider C, Adamcova M, Jick SS, Schlagenhauf P, Miller MK, Rhein HG, Meier CR.
Travel Med Infect Dis. 2013 Mar-Apr;11(2):71-80.
PMID: 23541791.
Excess Long-Term Mortality following Non-Variceal Upper Gastrointestinal Bleeding: A Population-
Based Cohort Study.
Crooks CJ, Card TR, West J.
PLoS Med. 2013 Apr;10(4):e1001437.
PMID: 23637580
Features of cancer in teenagers and young adults in primary care: a population-based nested case-control study.
Dommett RM, Redaniel MT, Stevens MC, Hamilton W, Martin RM.
Br J Cancer. 2013 Jun 11;108(11):2329-33.
PMID: 23619924.
Asthma management in pregnancy.
Charlton RA, Hutchison A, Davis KJ, de Vries CS.
PLoS One. 2013 Apr 4;8(4):e60247. d
PMID: 23593182.
Association of Barrett's Esophagus With Type II Diabetes Mellitus: Results From a Large
Population-Based Case-Control Study.
Iyer PG, Borah BJ, Heien HC, Das A, Cooper GS, Chak A.
Clin Gastroenterol Hepatol. 2013 Sep;11(9):1108-1114.e5
PMID: 23591277.
Acetaminophen use and change in blood pressure in a hypertensive population.
Dawson J, Fulton R, McInnes GT, Morton R, Morrison D, Padmanabhan S, Hewitt
J, Meredith P, Muir S, Dominiczak AF, Walters MR.
J Hypertens. 2013 Apr 12. [Epub ahead of print]
PubMed PMID: 23588196.
Orlistat and the risk of acute liver injury: self controlled case series study in UK Clinical Practice
Research Datalink.
Douglas IJ, Langham J, Bhaskaran K, Brauer R, Smeeth L.
BMJ. 2013 Apr 12;346:f1936.
PMID: 23585064
Cause-Specific Mortality of People With Barrett's Esophagus Compared With the General Population: A
Population-Based Cohort Study.
Solaymani-Dodaran M, Card TR, West J.
Gastroenterology. 2013 Jun;144(7):1375-1383.e1.
PMID: 23583429.
Impact and cost-effectiveness of a universal strategy to promote physical activity in primary care: population-based Cohort study and Markov model.
Gulliford MC, Charlton J, Bhattarai N, Charlton C, Rudisill C
Eur J Health Econ. 2013 Apr 10. [Epub ahead of print]
PMID: 23572044.
Juvenile Huntington's disease: a population-based study using the General Practice Research Database.
Douglas I, Evans S, Rawlins MD, Smeeth L, Tabrizi SJ, Wexler NS
BMJ Open. 2013 Apr 3;3(4). doi:pii: e002085.
PMID: 23558730
Antihypertensive drugs and the risk of congenital anomalies.
Vasilakis-Scaramozza C, Aschengrau A, Cabral HJ, Jick SS
Pharmacotherapy. 2013 May;33(5):476-82
PMID: 23553869.

56.
57.
58.
59.
60.
61.
62.
63.
64.
65.
Implications of comorbidity for primary care costs in the UK: a retrospective observational study.
Brilleman SL, Purdy S, Salisbury C, Windmeijer F, Gravelle H, Hollinghurst S.
Br J Gen Pract. 2013 Apr;63(609):e274-82.
PMID: 23540484
Temporal growth and geographic variation in the use of laboratory tests by NHS general practices: using routine data to identify research priorities.
Busby J, Schroeder K, Woltersdorf W, Sterne JA, Ben-Shlomo Y, Hay A,
Hollingworth W.
Br J Gen Pract. 2013 Apr;63(609):e256-66.
PMID: 23540482
Clinical features of kidney cancer in primary care: a case-control study using primary care records.
Shephard E, Neal R, Rose P, Walter F, Hamilton WT.
Br J Gen Pract. 2013 Apr;63(609):e250-5.
PMID:23540481
Androgen deprivation therapy and the risk of colorectal cancer in patients with prostate cancer.
Assayag
J, Yin H, Benayoun S, Pollak MN, Suissa S, Azoulay L
Cancer Causes Control. 2013 May;24(5):839-45.
PMID: 23546609.
Migraine, triptans, and the risk of developing rosacea: A population-based study within the United
Kingdom
Spoendlin J, Voegel JJ, Jick SS, Meier CR..
J Am Acad Dermatol. 2013 Sep;69(3):399-406
PMID: 23643255.
Variability of antibiotic prescribing in patients with chronic obstructive pulmonary disease exacerbations: a cohort study.
Boggon R, Hubbard R, Smeeth L, Gulliford M, Cassell J, Eaton S, Pirmohamed M, van Staa TP
BMC Pulm Med. 2013 May 31;13:32.
PMID: 23724907
An excess of prior irritable bowel syndrome diagnoses or treatments in Celiac disease: evidence of diagnostic delay.
Card TR, Siffledeen J, West J, Fleming KM.
Scand J Gastroenterol. 2013 Jul;48(7):801-7
PMID: 23697749.
Completeness and diagnostic validity of recording acute myocardial infarction events in primary care, hospital care, disease registry, and national mortality records: cohort study.
Herrett E, Shah AD, Boggon R, Denaxas S, Smeeth L, van Staa T, Timmis A,
Hemingway H.
BMJ. 2013 May 20;346:f2350.
PMID: 23692896.
The incidence of type 2 diabetes in the United Kingdom from 1991 to 2010.
Holden SH, Barnett AH, Peters JR, Jenkins-Jones S, Poole CD, Morgan CL, Currie
CJ.
Diabetes Obes Metab. 2013 Sep;15(9):844-52
PMID: 23675742.
Opioid Use for Noncancer Pain and Risk of Fracture in Adults: A Nested Case-Control Study Using the
General Practice Research Database.
Li L, Setoguchi S, Cabral H, Jick S.
Am J Epidemiol. 2013 Aug 15;178(4):559-69
PMID: 23639937.

66.
67.
68.
69.
70.
71.
72.
73.
74.
75.
76.
COX-2 selective nonsteroidal anti-inflammatory drugs and risk of gastrointestinal tract complications and myocardial infarction: an instrumental variable analysis.
Davies NM, Smith GD, Windmeijer F, Martin RM.
Epidemiology. 2013 May;24(3):352-62.
PMID: 23532054.
The determinants of cost-effectiveness potential: an historical perspective on lipid-lowering therapies.
Refoios Camejo R, McGrath C, Miraldo M, Rutten F.
Pharmacoeconomics. 2013 May;31(5):445-54.
PMID: 23572442.
Antidepressant Use During Early Pregnancy and the Risk of Congenital Anomalies.
Vasilakis-Scaramozza C, Aschengrau A, Cabral H, Jick SS.
Pharmacotherapy. 2013 Jun 6. [Epub ahead of print]
PMID: 23744675.
The efficiency of cardiovascular risk assessment: do the right patients get statin treatment? van Staa TP, Smeeth L, Ng ES, Goldacre B, Gulliford M.
Heart. 2013 Jun 4.
Heart 2013 11;99(21):1597-1602
PMID: 23735939.
Use of selective serotonin reuptake inhibitors in pregnancy and cardiac malformations: a propensity-score matched cohort in CPRD.
Margulis AV, Abou-Ali A, Strazzeri MM, Ding Y, Kuyateh F, Frimpong EY, Levenson MS, Hammad TA.
Pharmacoepidemiol Drug Saf. 2013 Sep;22(9):942-51
PMID: 23733623.
International collaboration to assess the risk of Guillain Barré Syndrome following Influenza A (H1N1)
2009 monovalent vaccines.
Dodd CN, Romio SA, Black S, Vellozzi C, Andrews N, Sturkenboom M, Zuber P, Hua W, Bonhoeffer J,
Buttery J, Crawford N, Deceuninck G, de Vries C, De Wals P, Gimeno MV, Heijbel H, Hughes H, Hur K, Hviid
A, Kelman J, Kilpi T, Chuang SK, Macartney K, Rett M, Lopez-Callada VR, Salmon D, Sanchez FG, Sanz N,
Silverman B, Storsaeter J, Thirugnanam U, van der Maas N, Yih K, Zhang T, Izurieta H; the Global H1N1 GBS
Consortium.
Vaccine. 2013 Sep 13;31(40):4448-58
PMID:23770307
The incidence of eating disorders in the UK in 2000-2009: findings from the General Practice Research
Database.
Micali N, Hagberg KW, Petersen I, Treasure JL.
BMJ Open. 2013 May 28;3(5).Print 2013.
PMID:23793681
Five-year fracture risk estimation in patients with Parkinson's disease.
Pouwels S, Bazelier MT, de Boer A, Weber WE, Neef CK, Cooper C, de Vries F.
Bone. 2013 Jun 22;56(2):266-270.
PMID:23800516
Case-control analysis on metformin and cancer of the esophagus.
Becker C, Meier CR, Jick SS, Bodmer M.
Cancer Causes Control. 2013 Oct
10;24(10):1763-1770.
PMID:23820930
Is cancer associated with polymyalgia rheumatica? A cohort study in the General Practice Research
Database.
Muller S, Hider SL, Belcher J, Helliwell T, Mallen CD.
Ann Rheum Dis. 2013 Jul 10.[Epub ahead of print]
PMID:23842460
Proton pump inhibitors and the risk of hospitalisation for community-acquired pneumonia: replicated cohort studies with meta-analysis.
Filion KB, Chateau D, Targownik LE, Gershon A, Durand M, Tamim H, Teare GF, Ravani P, Ernst P, Dormuth
CR; the CNODES Investigators.

77.
78.
79.
80.
81.
82.
83.
84.
85.
86.
87.
88.
Gut. 2013 Jul 15. [Epub ahead of print]
PMID:23856153
Androgen deprivation therapy and risk of acute kidney injury in patients with prostate cancer.
Lapi F, Azoulay L, Niazi MT, Yin H, Benayoun S, Suissa S.
JAMA. 2013 Jul 17;310(3):289-96. doi: 10.1001/jama.2013.8638.
PMID:23860987
Patterns of Risk of Cancer in Patients with Metal-on-Metal Hip Replacements versus Other Bearing
Surface Types: A Record Linkage Study between a Prospective Joint Registry and General Practice
Electronic Health Records in England.
Lalmohamed A, Macgregor AJ, de Vries F, Leufkens HG, van Staa TP.
PLoS One. 2013 Jul 4;8(7):e65891. Print 2013.
PMID:23861740
Impact of clinical trial findings on Bell's palsy management in general practice in the UK 2001-2012: interrupted time series regression analysis.
Morales DR, Donnan PT, Daly F, Staa TV, Sullivan FM.
BMJ Open. 2013 Jul 16;3(7). Print 2013.
PMID:23864211
Exposure to bisphosphonates and risk of common non-gastrointestinal cancers: series of nested casecontrol studies using two primary-care databases.
Vinogradova Y, Coupland C, Hippisley-Cox J.
Br J Cancer. 2013 Aug 6;109(3):795-806.Epub 2013 Jul 18.
PMID:23868009
Clinical Inertia in People With Type 2 Diabetes: A retrospective cohort study of more than 80,000 people.
Khunti K, Wolden ML, Thorsted BL, Andersen M, Davies MJ.
Diabetes Care. 2013 Jul 22. [Epub ahead of print]
PMID:23877982
Use of clopidogrel and proton pump inhibitors after a serious acute coronary event: Risk of coronary events and peptic ulcer bleeding.
Garcia Rodriguez LA, Johansson S, Cea Soriano L.
Thromb Haemost. 2013 Jul 25;110(4).
PMID:23884111
Association of childhood attention-deficit/hyperactivity disorder with atopic diseases and skin infections?
A matched case-control study using the General Practice Research Database.
Hak E, de Vries TW, Hoekstra PJ, Jick SS.
Ann Allergy Asthma Immunol. 2013 Aug;111(2):102-106.e2. Epub 2013 Jun 21.
PMID:23886227
Risk of incident stroke in patients with Alzheimer disease or vascular dementia.
Imfeld P, Bodmer M, Schuerch M, Jick SS, Meier CR.
Neurology. 2013 Jul 31. [Epub ahead of print]
PMID:23902701
The Incidence of First Venous Thromboembolism in and around Pregnancy Using Linked Primary and
Secondary Care Data: A Population Based Cohort Study from England and Comparative Meta-Analysis.
Abdul Sultan A, Tata LJ, Grainge MJ, West J.
PLoS One. 2013 Jul 29;8(7):e70310. Print 2013.
PMID:23922975
Cancer diagnosed by emergency admission in England: an observational study using the general practice research database.
Tsang C, Bottle A, Majeed A, Aylin P.
BMC Health Serv Res. 2013 Aug 14;13(1):308.
PMID:23941140
SLCO1B1 Genetic Variant Associated With Statin-Induced Myopathy: A Proof of Concept Study Using the Clinical Practice Research Datalink (CPRD).
Carr DF, O'Meara H, Jorgensen AL, Campbell J, Hobbs M, McCann G, van Staa T, Pirmohamed M.
Clin Pharmacol Ther. 2013 Aug 13.[Epub ahead of print]
PMID:23942138
Impact of lipid-lowering therapy on the prevalence of dyslipidaemia in patients at high-risk of cardiovascular events in UK primary care - a retrospective database study.
Jameson K, Amber V, D'Oca K, Mills D, Giles A, Ambegaonkar B.
Int J Clin Pract. 2013 Aug 14. [Epub ahead of print]
PMID: 23944233

89.
90.
91.
92.
93.
94.
95.
96.
97.
98.
99.
100.
101.
102.
Impact of deprivation on occurrence, outcomes and health care costs of people with multiple morbidity.
Charlton J, Rudisill C, Bhattarai N, Gulliford M.
J Health Serv Res Policy. 2013 Aug 14. [Epub ahead of print]
PMID:23945679
Risk of fracture in patients with muscular dystrophies.
Pouwels S, de Boer A, Leufkens HG, Weber WE, Cooper C, van Onzenoort HA, de Vries F.
Osteoporos Int. 2013 Aug 15. [Epub ahead of print]
PMID:23948807
Predicting risk of emergency admission to hospital using primary care data: derivation and validation of
QAdmissions score.
Hippisley-Cox J, Coupland C.
BMJ Open. 2013 Aug 19;3(8):e003482.
PMID:23959760
Gout is an independent risk factor for all types of vascular disease: a retrospective cohort study in the UK
General Practice Research Database.
Clarson, Lorna E.; Hider, Samantha L.; Belcher, John; et al.
Rheumatology. 2013;52:38-39.
Socio-economic position and childhood multimorbidity: a study using linkage between the Avon
Longitudinal study of parents and children and the general practice research database.
Cornish RP, Boyd AW, Van Staa T, Salisbury C, Macleod J.
Int J Equity Health. 2013 Aug 20;12(1):66.
PMID:23962118
Declining Genital Warts in Young Women in England Associated with HPV 16/18 Vaccination: An
Ecological Study.
Howell-Jones R, Soldan K, Wetten S, Meser D, Williams T, Gill ON, Hughes G.
J Infect Dis. 2013 Nov;208:1397-1403.
The use of metformin and colorectal cancer incidence in patients with type II diabetes mellitus.
Smiechowski B, Azoulay L, Yin H, Pollak MN, Suissa S.
Cancer Epidemiol Biomarkers Prev. 2013 Oct;22(10):1877-83. Epub 2013 Aug 21.
PMID:23966577
Adverse events recorded in English primary care: observational study using the General Practice
Research Database.
Tsang C, Bottle A, Majeed A, Aylin P.
Br J Gen Pract. 2013 Aug;63(613):e534-42.
PMID:23972194
Risk of colorectal cancer after initiation of orlistat: matched cohort study.
Hong JL, Meier CR, Sandler RS, Jick SS, Stürmer T.
BMJ. 2013 Aug 27;347:f5039.
PMID:23982291
Non-steroidal anti-inflammatory drug use and brain tumour risk: a case-control study within the Clinical
Practice Research Datalink.
Bannon FJ, O'Rorke MA, Murray LJ, Hughes CM, Gavin AT, Fleming SJ, Cardwell CR.
Cancer Causes Control. 2013 Nov;24(11):2027-34. Epub 2013 Aug 30.
PMID:23990380
Risk of uterine cancer in symptomatic women in primary care: case-control study using electronic records.
Walker S, Hyde C, Hamilton W.
Br J Gen Pract. 2013 Sep;63(614):e643-8.
PMID:23998845
Bivalent human papillomavirus vaccine and the risk of fatigue syndromes in girls in the UK.
Donegan K, Beau-Lejdstrom R, King B, Seabroke S, Thomson A, Bryan P.
Vaccine. 2013 Oct 9;31(43):4961-7. Epub 2013 Sep 1.
PMID:24001935
Determining the predictive value of Read codes to identify congenital cardiac malformations in the UK
Clinical Practice Research Datalink.
Hammad TA, Margulis AV, Ding Y, Strazzeri MM, Epperly H.
Pharmacoepidemiol Drug Saf. 2013 Nov;22(11):1233-8.
PMID:24002995
Use of acid-suppressive drugs in pregnancy and the risk of childhood asthma: bidirectional crossover study using the general practice research database.

103.
104.
105.
106.
107.
108.
109.
110.
111.
112.
113.
114.
Hak E, Mulder B, Schuiling-Veninga CC, de Vries TW, Jick SS.
Drug Saf. 2013 Nov;36(11):1097-104.
PMID:24018582
Acute maternal infection and risk of pre-eclampsia: a population-based case-control study.
Minassian C, Thomas SL, Williams DJ, Campbell O, Smeeth L.
PLoS One. 2013 Sep 3;8(9):e73047. doi: 10.1371/journal.pone.0073047.
PMID:24019891
Use of anti-malarial drugs and the risk of developing eye disorders.
Schneider C, Adamcova M, Jick SS, Schlagenhauf P, Miller MK, Rhein HG, Meier CR.
Travel Med Infect Dis. 2013 Aug 28. pii: S1477-8939(13)00135-X. [Epub ahead of print]
PMID:24035311
Representativeness and optimal use of body mass index (BMI) in the UK Clinical Practice Research
Datalink (CPRD).
Bhaskaran K, Forbes HJ, Douglas I, Leon DA, Smeeth L.
BMJ Open. 2013 Sep 13;3(9):e003389.
PMID:24038008
Physicians' prescribing preferences were a potential instrument for patients' actual prescriptions of antidepressants.
Davies NM, Gunnell D, Thomas KH, Metcalfe C, Windmeijer F, Martin RM.
J Clin Epidemiol. 2013 Dec;66(12):1386-96. doi: 10.1016/j.jclinepi.2013.06.008. Epub 2013 Sep 24.
PMID:24075596
External Validation of the UKPDS Risk Engine in Incident Type 2 Diabetes: a need for new risk type 2 diabetes-specific risk equations.
Bannister CA, Poole CD, Jenkins-Jones S, Morgan CL, Elwyn G, Spasic I, Currie CJ.
Diabetes Care. 2013 Oct 2. [Epub ahead of print]
PMID:24089541
The relative risk of aortic aneurysm in patients with giant cell arteritis compared with the general population of the UK.
Robson JC, Kiran A, Maskell J, Hutchings A, Arden N, Dasgupta B, Hamilton W, Emin A, Culliford D,
Luqmani RA.
Ann Rheum Dis. 2013 Oct 4. [Epub ahead of print]
PMID:24095936
Falling Threshold for Treatment of Borderline Elevated Thyrotropin Levels-Balancing Benefits and
Risks: Evidence From a Large Community-Based Study.
Taylor PN, Iqbal A, Minassian C, Sayers A, Draman MS, Greenwood R, Hamilton W, Okosieme O, Panicker V,
Thomas SL, Dayan C.
JAMA Intern Med. 2013 Oct 7. [Epub ahead of print]
PMID:24100714
General practice-recorded depression and antidepressant use in young people with newly diagnosed Type
1 diabetes: a cohort study using the Clinical Practice Research Datalink.
Morgan E, Patterson CC, Cardwell CR.
Diabet Med. 2013 Sep 30. [Epub ahead of print]
PMID:24111949
Pregnancy losses in women with Type 1 or Type 2 diabetes in the UK: an investigation using primary care records.
McGrogan A, Snowball J, de Vries CS.
Diabet Med. 2013 Sep 30. [Epub ahead of print]
PMID:24111989
Rates and risk of hospitalisation among patients with type 2 diabetes: retrospective cohort study using the
UK General Practice Research Database linked to English Hospital Episode Statistics.
Khalid JM, Raluy-Callado M, Curtis BH, Boye KS, Maguire A, Reaney M.
Int J Clin Pract. 2014 Jan;68(1):40-8. Epub 2013 Sep 23.
PMID:24112108
Obesity paradox in people newly diagnosed with type 2 diabetes with and without prior cardiovascular disease.
Thomas G, Khunti K, Curcin V, Molokhia M, Millett C, Majeed A, Paul S.
Diabetes Obes Metab. 2013 Oct 1. [Epub ahead of print]
PMID:24118783
The prevalence and incidence, resource use and financial costs of treating people with attention deficit/hyperactivity disorder (ADHD) in the United Kingdom (1998 to 2010).

115.
116.
117.
118.
119.
120.
121.
122.
123.
124.
125.
126.
127.
Holden SE, Jenkins-Jones S, Poole CD, Morgan CL, Coghill D, Currie CJ.
Child Adolesc Psychiatry Ment Health. 2013 Oct 11;7(1):34.
PMID:24119376
Smoking cessation treatment and risk of depression, suicide, and self harm in the Clinical Practice
Research Datalink: prospective cohort study.
Thomas KH, Martin RM, Davies NM, Metcalfe C, Windmeijer F, Gunnell D.
BMJ. 2013 Oct 11;347:f5704. doi: 10.1136/bmj.f5704.
PMID:24124105
1 and 5 year survival estimates for people with cirrhosis of the liver in England, 1998-2009: A large population study.
Ratib S, Fleming KM, Crooks CJ, Aithal GP, West J.
J Hepatol. 2013 Oct 12. pii: S0168-8278(13)00691-0. [Epub ahead of print]
PMID:24128415
Prevalence and incidence rates of autism in the UK: time trend from 2004-2010 in children aged 8 years.
Taylor B, Jick H, Maclaughlin D.
BMJ Open. 2013 Oct 16;3(10):e003219.
PMID:24131525
Impact of body mass index on prevalence of multimorbidity in primary care: cohort study.
Booth HP, Prevost AT, Gulliford MC.
Fam Pract. 2013 Oct 16. [Epub ahead of print]
PMID:24132593
A simple prediction rule for all-cause mortality in a cohort eligible for bariatric surgery.
Padwal RS, Klarenbach SW, Wang X, Sharma AM, Karmali S, Birch DW, Majumdar SR.
JAMA Surg. 2013 Dec 1;148(12):1109-15.
PMID:24132685
Only modest long-term opioid dose escalation occurs over time in chronic nonmalignant pain management.
Chapman CR, Bradshaw DH.
J Pain Palliat Care Pharmacother. 2013 Dec;27(4):370-7. Epub 2013 Oct 21.
PMID:24143927
Use of diuretics and risk of incident gout: Population-based case-control study.
Bruderer S, Jick SS, Bodmer M, Meier CR.
Arthritis Rheum. 2013 Oct 21. [Epub ahead of print]
PMID:24151149
Risk of first venous thromboembolism in pregnant women in hospital: population based cohort study from England.
Abdul Sultan A, West J, Tata LJ, Fleming KM, Nelson-Piercy C, Grainge MJ.
BMJ. 2013 Nov 7;347:f6099.
PMID:24201164
Type and timing of heralding in ST-elevation and non-ST-elevation myocardial infarction: an analysis of prospectively collected electronic healthcare records linked to the national registry of acute coronary syndromes.
Herrett E, George J, Denaxas S, Bhaskaran K, Timmis A, Hemingway H, Smeeth L.
Eur Heart J Acute Cardiovasc Care. 2013 Sep;2(3):235-45.
PMID:24222835
Population-based study of presentation and adverse outcomes after femoral hernia surgery.
Humes DJ, Radcliffe RS, Camm C, West J.
Br J Surg. 2013 Dec;100(13):1827-32.
PMID:24227371
The association between psychiatric diseases, psychotropic drugs and the risk of incident rosacea.
Spoendlin J, Bichsel F, Voegel JJ, Jick SS, Meier CR.
Br J Dermatol. 2013 Nov 14. [Epub ahead of print]
PMID:24236423
Low-Dose Aspirin Use After Diagnosis of Colorectal Cancer Does Not Increase Survival: A Case-Control
Analysis of a Population-Based Cohort.
Cardwell CR, Kunzmann AT, Cantwell MM, Hughes C, Baron JA, Powe DG, Murray LJ.
Gastroenterology. 2013 Nov 15. pii: S0016-5085(13)01595-3. [Epub ahead of print]
PMID:24239563
Validity of smoking prevalence estimates from primary care electronic health records compared with national population survey data for England, 2007 to 2011.

128.
129.
130.
131.
132.
133.
134.
135.
136.
137.
138.
139.
Booth HP, Prevost AT, Gulliford MC.
Pharmacoepidemiol Drug Saf. 2013 Oct 21. [Epub ahead of print]
PMID:24243711
Effect of β blockers on mortality after myocardial infarction in adults with COPD: population based cohort study of UK electronic healthcare records.
Quint JK, Herrett E, Bhaskaran K, Timmis A, Hemingway H, Wedzicha JA, Smeeth L.
BMJ. 2013 Nov 22;347:f6650.
PMID:24270505
Exploiting the potential of large databases of electronic health records for research using rapid search algorithms and an intuitive query interface.
Tate AR, Beloff N, Al-Radwan B, Wickson J, Puri S, Williams T, Van Staa T, Bleach A.
J Am Med Inform Assoc. 2013 Nov 22. [Epub ahead of print]
PMID:24272162
Association between cardiovascular events and sodium-containing effervescent, dispersible, and soluble drugs: nested case-control study.
George J, Majeed W, Mackenzie IS, Macdonald TM, Wei L.
BMJ. 2013 Nov 26;347:f6954. doi: 10.1136/bmj.f6954.
PMID:24284017
Risk of acute myocardial infarction, stroke, or death in patients initiating olmesartan or other angiotensin receptor blockers - a cohort study using the Clinical Practice Research Datalink.
Zhou EH, Gelperin K, Levenson MS, Rose M, Hsueh YH, Graham DJ.
Pharmacoepidemiol Drug Saf. 2013 Nov 28. [Epub ahead of print]
PMID:24285502
A population-based survival analysis describing the association of body mass index on time to revision for total hip and knee replacements: results from the UK general practice research database.
Culliford D, Maskell J, Judge A, Arden NK; COAST Study group.
BMJ Open. 2013 Nov 27;3(11):e003614.
PMID:24285628
Adjusting for measurement error in baseline prognostic biomarkers included in a time-to-event analysis: a joint modelling approach.
Crowther MJ, Lambert PC, Abrams KR.
BMC Med Res Methodol. 2013 Dec 1;13:146.
PMID:24289257
Elevated risk of clinical fractures and associated risk factors in patients with systemic lupus erythematosus versus matched controls: a population-based study in the United Kingdom.
Bultink IE, Harvey NC, Lalmohamed A, Cooper C, Lems WF, van Staa TP, de Vries F.
Osteoporos Int. 2013 Dec 3. [Epub ahead of print]
PMID:24297094
Primary prevention of diabetic retinopathy with fibrates: a retrospective, matched cohort study.
Morgan CL, Owens DR, Aubonnet P, Carr ES, Jenkins-Jones S, Poole CD, Currie CJ.
BMJ Open. 2013 Dec 3;3(12):e004025. doi: 10.1136/bmjopen-2013-004025.
PMID:24302508
Electronic Health Records For Biological Sample Collection: Feasibility Study Of Statin-Induced
Myopathy Using The Clinical Practice Research Datalink.
O'Meara H, Carr DF, Evely J, Hobbs M, McCann G, van Staa T, Pirmohamed M.
Br J Clin Pharmacol. 2013 Oct 28. doi: 10.1111/bcp.12269. [Epub ahead of print]
PMID:24308359
Low-dose aspirin and survival in men with prostate cancer: a study using the UK Clinical Practice
Research Datalink.
Cardwell CR, Flahavan EM, Hughes CM, Coleman HG, O'Sullivan JM, Powe DG, Murray LJ.
Cancer Causes Control. 2013 Dec 6. [Epub ahead of print]
PMID:24310109
Statin Use is Associated With Reduced Risk of Histologic Subtypes of Esophageal Cancer: a Nested Case-
Control Analysis.
Alexandre L, Clark AB, Bhutta HY, Holt S, Lewis MP, Hart AR.
Gastroenterology. 2013 Dec 5. pii: S0016-5085(13)01727-7. doi: 10.1053/j.gastro.2013.11.046. [Epub ahead of print]
PMID:24315828
Ischaemic cardiac events and use of strontium ranelate in postmenopausal osteoporosis: a nested casecontrol study in the CPRD.

140.
141.
142.
143.
144.
145.
146.
147.
148.
149.
150.
151
Cooper C, Fox KM, Borer JS.
Osteoporos Int. 2013 Dec 10. [Epub ahead of print]
PMID:24322476
Completeness and usability of ethnicity data in UK-based primary care and hospital databases.
Mathur R, Bhaskaran K, Chaturvedi N, Leon DA, Vanstaa T, Grundy E, Smeeth L.
J Public Health (Oxf). 2013 Dec 8. [Epub ahead of print]
PMID:24323951
The association of vitamin D supplementation with the risk of cancer in postmenopausal women.
Redaniel MT, Gardner MP, Martin RM, Jeffreys M.
Cancer Causes Control. 2013 Dec 15. [Epub ahead of print]
PMID:24337883
New estimates of the burden of acute community-acquired infections among older people with diabetes mellitus: a retrospective cohort study using linked electronic health records.
McDonald HI, Nitsch D, Millett ER, Sinclair A, Thomas SL.
Diabet Med. 2013 Dec 16. [Epub ahead of print]
PMID:24341529
Initiation of warfarin in patients with atrial fibrillation: early effects on ischaemic strokes.
Azoulay L, Dell'aniello S, Simon TA, Renoux C, Suissa S.
Eur Heart J. 2013 Dec 18. [Epub ahead of print]
PMID:24353282
Comparison of cancer diagnostic intervals before and after implementation of NICE guidelines: analysis of data from the UK General Practice Research Database.
Neal RD, Din NU, Hamilton W, Ukoumunne OC, Carter B, Stapley S, Rubin G.
Br J Cancer. 2013 Dec 24. [Epub ahead of print]
PMID:24366304
The risk of a subsequent cancer diagnosis after herpes zoster infection: primary care database study.
S J Cotton, J Belcher, P Rose, S K Jagadeesan and R D Neal
Br J Cancer. 2013 2013 Jan 29 [Epub ahead of print]
Comorbidities Affect Risk of Nonvariceal Upper Gastrointestinal Bleeding.
Crooks CJ, West J, Card TR.
Gastroenterology. 2013. 144(7):1384-1393.
Incidence of psychoses among drug dependent patients in primary care with no psychiatric history: A retrospective observational matched-cohort study.
Frisher M, Martino O, Bashford J, Crome I, Croft P.
European Journal of Psychiatry. 2013. 27.4: 240-247.
Beta-blocker usage and breast cancer survival: a nested case-control study within a UK clinical practice research datalink cohort.
Cardwell CR, Coleman HG, Murray LJ, Entschladen F, Powe DG.
Int J Epidemiol. 2013 Dec;42(6):1852-61.
Non-steroidal anti-inflammatory drug use and cervical cancer risk: A case-control study using the Clinical
Practice Research Datalink.
Wilson JC, O'Rorke MA, Cooper JA, Murray LJ, Hughes CM, Gormley GJ, Anderson LA.
Cancer Epidemiol. 2013 Dec;37(6):897-904.
β-Blocker usage and colorectal cancer mortality: A nested case-control study in the UK clinical practice research datalink cohort.
Hicks BM, Murray LJ, Powe DG, Hughes CM, Cardwell CR.
Ann Oncol. 2013 Dec;24(12):3100-6.
Colorectal cancer risk reduction following macrogol exposure: A cohort and nested case control study in the UK.
Charlton RA, Snowball JM, Bloomfield K, De Vries CS.
PLOS One. (Dec 20, 2013).
1.
Use of Antidiabetic Agents and the Risk of Pancreatic Cancer: A Case-Control Analysis.
Bodmer M, Becker C, Meier C, Jick SS, Meier CR.
Am J Gastroenterol. 2012 Apr;107(4):620-6

2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
PMID: 22290402.
Non-Steroidal Anti-Inflammatory Drugs and The Risk of Clostridium Difficile-Associated Disease.
Suissa D, Delaney JA, Dial S, Brassard P.
Br J Clin Pharmacol. 2012 Aug;74(2):370-5.
PMID: 22283873.
Dopamine agonist use and the risk of heart failure.
Renoux C, Dell'Aniello S, Brophy JM, Suissa S.
Pharmacoepidemiol Drug Saf. 2012 Jan;21(1):34-41. doi:10.1002/pds.2267. Epub 2011 Nov 23.
PMID: 22109939.
Proton pump inhibitors and histamine-2-receptor antagonists and pancreatic cancer risk: a nested casecontrol study.
Bradley MC, Murray LJ, Cantwell MM, Hughes CM.
Br J Cancer. 2012 Jan 3;106(1):233-9. doi:10.1038/bjc.2011.511. Epub 2011 Nov 22.
PMID: 22108522
Extracting diagnoses and investigation results from unstructured text in electronic health records by semi-supervised machine learning.
Wang Z, Shah AD, Tate AR, Denaxas S, Shawe-Taylor J, Hemingway H.
PLoS One. 2012;7(1):e30412. Epub 2012 Jan 19.
PMID: 22276193
Coding, recording and incidence of different forms of coronary heart disease in primary care.
Bhattarai N, Charlton J, Rudisill C, Gulliford MC.
PLoS One. 2012;7(1):e29776. Epub 2012 Jan 19.
PMID: 22276128
Quality of INR Control and Outcomes Following Venous Thromboembolism.
Gallagher AM, de Vries F, Plumb JM, Haß B, Clemens A, van Staa TP.
Clin Appl Thromb Hemost. 2012 Jul;18(4):370-8
PMID: 22275390.
Jaundice in primary care: a cohort study of adults aged >45 years using electronic medical records.
Taylor A, Stapley S, Hamilton W.
Fam Pract. 2012 Aug;29(4):416-20
PMID: 22247287.
Features of childhood cancer in primary care: a population-based nested case-control study.
Dommett RM, Redaniel MT, Stevens MC, Hamilton W, Martin RM.
Br J Cancer. 2012 Jan 12. doi: 10.1038/bjc.2011.600.
PMID: 22240793.
Co-administration of statins with cytochrome P450 3A4 inhibitors in a UK primary care population.
Bakhai A, Rigney U, Hollis S, Emmas C.
Pharmacoepidemiol Drug Saf. 2012 Jan 12. doi: 10.1002/pds.2308. [Epub ahead of print]
PMID: 22237927.
Treatment pathways for patients with atrial fibrillation.
Hodgkinson JA, Taylor CJ, Hobbs FD.
Int J Clin Pract. 2012 Jan;66(1):44-52. doi:10.1111/j.1742-1241.2011.02818.x.
PMID: 22171904.
Pragmatic randomised trials using routine electronic health records: putting them to the test.
Staa TP, Goldacre B, Gulliford M, Cassell J, Pirmohamed M, Taweel A, Delaney B, Smeeth L.
BMJ. 2012 Feb 7;344:e55. doi: 10.1136/bmj.e55.
PMID: 22315246.

21.
22.
23.
13.
Drospirenone- and levonorgestrel-containing oral contraceptives and the risk of gallbladder disease.
Jick S, Pennap D.
Contraception. 2012 Sep;86(3):220-3
PMID: 22325114.
Use of metformin is not associated with a decreased risk of colorectal cancer: a case-control analysis.
Bodmer M, Becker C, Meier C, Jick SS, Meier CR.
14. Cancer Epidemiol Biomarkers Prev. 2012 Feb;21(2):280-6. Epub 2011 Dec 16.
PMID: 22178569.
15.
Suicide risk in primary care patients with major physical diseases: a case-control study.
Webb RT, Kontopantelis E, Doran T, Qin P, Creed F, Kapur N.
Arch Gen Psychiatry. 2012 Mar;69(3):256-64.
PMID: 22393218.
16. Clinical characteristics and patterns of healthcare utilization in patients with painful neuropathic disorders in UK general practice: a retrospective cohort study.
Berger A, Sadosky A, Dukes E, Edelsberg J, Oster G.
BMC Neurol. 2012 Mar 6;12:8.
PMID: 22394606
17. Health service use in families where children enter public care: a nested case control study using the
General Practice Research Database.
Simkiss DE, Spencer NJ, Stallard N, Thorogood M.
BMC Health Serv Res. 2012 Mar 16;12:65.
PMID: 22424404
18.
19.
20.
Healthcare utilization among patients with depression before and after initiating duloxetine in the United Kingdom .
Shi N, Cao Z, Durden E, Schacht A, Torres A, Happich M.
J Med Econ. 2012;15(4):672-80.
PMID: 22390770
Angiotensin receptor blockers and risk of cancer: cohort study among people receiving antihypertensive drugs in UK General Practice Research Database.
Bhaskaran K, Douglas I, Evans S, van Staa T, Smeeth L.
BMJ. 2012 Apr 24;344:e2697.
PMID: 22531797
Fracture rate in patients with myasthenia gravis: the general practice research database.
Pouwels S, de Boer A, Javaid MK, Hilton-Jones D, Verschuuren J, Cooper C, Leufkens HG, de Vries F.
Osteoporos Int. 2013 Feb;24(2):467-76
PMID: 22531999.
Incidence, Mortality, and Disease Associations of Pyoderma Gangrenosum in the United Kingdom: A
Retrospective Cohort Study.
Langan SM, Groves RW, Card TR, Gulliford MC.
J Invest Dermatol. 2012 Apr 26.
PMID: 22534879.
Comorbidities and Concomitant Medication Use in Men with Prostate Cancer or High Levels of PSA
Compared to Matched Controls: A GPRD Analysis
Li H, Hodgson E, Watson L, Shukla A, Nelson JJ.
J Cancer Epidemiol. 2012;2012:291704
PMID: 22570655
Risk of tuberculosis in pregnancy: a national, primary care-based cohort and self-controlled case series study .
Zenner D, Kruijshaar ME, Andrews N, Abubakar I.

24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
Am J Respir Crit Care Med. 2012 Apr 1;185(7):779-84.
PMID: 22161161.
Metformin, other antidiabetic drugs, and risk of Alzheimer's disease: a population-based case-control study.
Imfeld P, Bodmer M, Jick SS, Meier CR.
J Am Geriatr Soc. 2012 May;60(5):916-21
PMID: 22458300.
A study on the epidemiology of rosacea in the U.K.
Spoendlin J, Voegel JJ, Jick SS, Meier CR.
Br J Dermatol. 2012 May 5.
PMID: 22564022.
The Risk of Adverse Outcomes in Association with Use of Testosterone Products: A Cohort Study using the UK-based General Practice Research Database.
Jick SS, Hagberg KW.
Br J Clin Pharmacol. 2012 May 11.
PMID: 22574772.
Hormone replacement therapy is associated with gastro-oesophageal reflux disease: a retrospective cohort study.
Close H, Mason JM, Wilson D, Hungin AP.
BMC Gastroenterol. 2012 May 29;12:56.
PMID: 22642788
The use of pioglitazone and the risk of bladder cancer in people with type 2 diabetes: nested case-control study.
Azoulay L, Yin H, Filion KB, Assayag J, Majdan A, Pollak MN, Suissa S.
BMJ. 2012 May 30;344:e3645.
PMID: 22653981
Pioglitazone and bladder cancer: A propensity score matched cohort study.
Li W, Macdonald TM, Mackenzie IS.
Br J Clin Pharmacol. 2012 May 11.
PMID: 22574756.
The lifetime risk of total hip and knee arthroplasty: results from the UK general practice research database.
Culliford DJ, Maskell J, Kiran A, Judge A, Javaid MK, Cooper C, Arden NK.
Osteoarthritis Cartilage. 2012 Jun;20(6):519-24.
PMID: 22395038.
The risk of pancreatic cancer in symptomatic patients in primary care: a large case-control study using electronic records.
Stapley S, Peters TJ, Neal RD, Rose PW, Walter FM, Hamilton W.
Br J Cancer. 2012 Jun 5;106(12):1940-4.
PMID: 22617126
Association between appendicectomy in females and subsequent pregnancy rate: a cohort study.
Wei L, Macdonald T, Shimi S.
Fertil Steril. 2012 Aug;98(2):401-5.
PMID: 22683011.
Predictors of Treatment with Duloxetine or Venlafaxine XR among Adult Patients Treated for Depression in Primary Care Practices in the United Kingdom.
Shi N, Durden E, Torres A, Cao Z, Happich M.
Depress Res Treat. 2012;2012:815363.
PMID: 22720149

34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
A net clinical benefit analysis of warfarin and aspirin on stroke in patients with atrial fibrillation: a nested case-control study.
Azoulay L, Dell'aniello S, Simon TA, Langleben D, Renoux C, Suissa S.
BMC Cardiovasc Disord. 2012 Jun 26;12(1):49.
PMID: 22734842.
Comparison of prescription drug costs in the United States and the United Kingdom, part 2: proton pump inhibitors.
Jick H, Wilson A, Wiggins P, Chamberlain DP.
Pharmacotherapy 2012 Jun;32(6):489-92.
PMID: 22511180.
Incidence of the Pneumoconioses in the United Kingdom General Population between 1997 and 2008.
Amar RK, Jick SS, Rosenberg D, Maher TM, Meier CR.
Respiration. 2012;84(3):200-6.
PMID: 22678015.
Validity of cancer diagnosis in a primary care database compared with linked cancer registrations in
England. Population-based cohort study
Dregan A, Moller H, Murray-Thomas T, Gulliford MC.
Cancer Epidemiol. 2012 Oct;36(5):425-9
PMID: 22727737.
Causes of death in patients with multiple sclerosis and matched referent subjects: a population-based cohort study.
Lalmohamed A, Bazelier MT, Van Staa TP, Uitdehaag BM, Leufkens HG, De Boer A,
De Vries F.
Eur J Neurol. 2012 Jul;19(7):1007-14.
PMID: 22353360.
Trends in antiepileptic drug utilisation in UK primary care 1993-2008: Cohort study using the General Practice Research Database.
Nicholas JM, Ridsdale L, Richardson MP, Ashworth M, Gulliford MC.
Seizure. 2012 Jul;21(6):466-70.
PMID: 22608976.
An algorithm to identify medical practices common to both the General Practice Research Database and
The Health Improvement Network database.
Cai B, Xu W, Bortnichak E, Watson DJ.
Pharmacoepidemiol Drug Saf. 2012 Jul;21(7):770-774.
PMID: 22544805.
Safety of saxagliptin: rationale for and design of a series of postmarketing observational studies
Lo Re V 3rd, Haynes K, Ming EE, Wood Ives J, Horne LN, Fortier K, Carbonari DM, Hennessy S, Cardillo S,
Reese PP, Reddy KR, Margolis D, Apter A, Kimmel SE, Roy J, Freeman CP, Razzaghi H, Holick CN, Esposito
DB, Van Staa TP, Bhullar H, Strom BL.
Pharmacoepidemiol Drug Saf. 2012 Nov;21(11):1202-15
PMID: 22763953.
Evaluation of Adverse Outcome in Young Women with Polycystic Ovary Syndrome Versus Matched,
Reference Controls: A Retrospective, Observational Study.
Morgan CL, Jenkins-Jones S, Currie CJ, Rees DA.
J Clin Endocrinol Metab. 2012 Sep;97(9):3251-60
PMID: 22767635.
Clopidogrel and interaction with proton pump inhibitors: comparison between cohort and within person study designs.
Douglas IJ, Evans SJ, Hingorani AD, Grosso AM, Timmis A, Hemingway H, Smeeth L.
BMJ. 2012 Jul 10;345:e4388.

44.
45.
PMID: 22782731
Spironolactone and risk of incident breast cancer in women older than 55 years: retrospective, matched cohort study .
Mackenzie IS, Macdonald TM, Thompson A, Morant S, Wei L.
BMJ. 2012 Jul 13;345:e4447.
PMID: 22797844
Discontinuation of beta-blockers in cardiovascular disease: UK primary care cohort study.
Kalra PR, Morley C, Barnes S, Menown I, Kassianos G, Padmanabhan S, Gupta S, Lang CC.
Int J Cardiol. 2012 Jul 26. [Epub ahead of print]
PMID: 22840685.
46.
47.
48.
49.
50.
51.
52.
53.
Community Care in England: Reducing Socioeconomic Inequalities in Heart Failure.
Hawkins NM, Scholes S, Bajekal M, Love H, O'Flaherty M, Raine R, Capewell S.
Circulation. 2012 Aug 28;126(9):1050-7
PMID: 22837162.
Impact of Diabetes Duration and Chronic Pancreatitis on the Association between Type 2 Diabetes And
Pancreatic Cancer Risk.
Brodovicz KG, Kou TD, Alexander CM, O'Neill EA, Engel SS, Girman CJ, Goldstein BJ.
Diabetes Obes Metab. 2012 Jul 25;9999(9999)
PMID: 22831166.
Epidemiology of clinical body mass index recording in an obese population in primary care: a cohort study.
Booth HP, Prevost AT, Gulliford MC.
J Public Health (Oxf). 2013 Mar;35(1):67-74
PMID: 22829663.
A retrospective comparison of acute rhinosinusitis outcomes in patients prescribed antibiotics, mometasone furoate nasal spray, or both. de Moor C, Reardon G, McLaughlin J, Maiese EM, Navaratnam P.
Am J Rhinol Allergy. 2012 Jul;26(4):308-14.
PMID: 22801020.
Resource utilization and outcomes in patients with atrial fibrillation: a case control study.
Boggon R, Lip GY, Gallagher AM, van Staa TP.
Appl Health Econ Health Policy. 2012 Jul 1;10(4):249-59.
PMID: 22540235.
Colorectal cancer incidence on the General Practice Research Database.
Charlton R, Snowball J, Bloomfield K, de Vries C.
Pharmacoepidemiol Drug Saf. 2012 Jul;21(7):775-783.
PMID: 22383247.
Incidence of Genital Infection Among Patients with Type 2 Diabetes in the UK General Practice Research
Database .
Hirji I, Andersson SW, Guo Z, Hammar N, Gomez-Caminero A.
J Diabetes Complications. 2012 Nov;26(6):501-5.
PMID: 22840886.
Resource Use and Costs Associated with Coeliac Disease before and after Diagnosis in 3,646 Cases:
Results of a UK Primary Care Database Analysis.
Violato M, Gray A, Papanicolas I, Ouellet M.
PLoS One. 2012;7(7):e41308.
PMID: 22815991
Drug-/radiation-induced interstitial lung disease in the United Kingdom general population: Incidence, all-cause mortality and characteristics at diagnosis.

54. Amar RK, Jick SS, Rosenberg D, Maher TM, Meier CR.
Respirology. 2012 Jul;17(5):861-868.
PMID: 22563933
55.
Increased risk of miscarriage and ectopic pregnancy among women with irritable bowel syndrome.
Khashan AS, Quigley EM, McNamee R, McCarthy FP, Shanahan F, Kenny LC.
Clin Gastroenterol Hepatol. 2012 Aug;10(8):902-9.
PMID: 22373726.
56.
57.
Risk of self-harm in physically ill patients in UK primary care.
Webb RT, Kontopantelis E, Doran T, Qin P, Creed F, Kapur N.
J Psychosom Res. 2012 Aug;73(2):92-7.
PMID: 22789410.
Risk of fracture after bariatric surgery in the United Kingdom: population based, retrospective cohort study.
Lalmohamed A, de Vries F, Bazelier MT, Cooper A, van Staa TP, Cooper C, Harvey NC.
BMJ. 2012 Aug 3;345:e5085.
PMID: 22867649
The natural history of community-acquired pneumonia in COPD patients: A population database
58.
59. analysis.
Müllerova H, Chigbo C, Hagan GW, Woodhead MA, Miravitlles M, Davis KJ, Wedzicha JA.
Respir Med. 2012 Aug;106(8):1124-33.
PMID: 22621820.
The Freetext Matching Algorithm: a computer program to extract diagnoses and causes of death from unstructured text in electronic health records.
Shah AD, Martinez C, Hemingway H
BMC Med Inform Decis Mak. 2012 Aug 7;12(1):88.
PMID: 22870911
60.
Association of systolic and diastolic blood pressure and all cause mortality in people with newly diagnosed type 2 diabetes: retrospective cohort study.
Vamos EP, Harris M, Millett C, Pape UJ, Khunti K, Curcin V, Molokhia M, Majeed A.
BMJ. 2012 Aug 30;345:e5567.
PMID: 22936794
61. A simple score for estimating the long-term risk of fracture in patients with multiple sclerosis.
Bazelier MT, van Staa TP, Uitdehaag BM, Cooper C, Leufkens HG, Vestergaard P,
Bentzen J, de Vries F.
Neurology. 2012 Aug 28;79(9):922-8.
PMID: 22895583
62. Recorded quality of primary care for patients with diabetes in England before and after the introduction of a financial incentive scheme: a longitudinal observational study.
Kontopantelis E, Reeves D, Valderas JM, Campbell S, Doran T.
BMJ Qual Saf. 2013 Jan;22(1):53-64
PMID: 22918988.
63. Epilepsy, suicidality, and psychiatric disorders: a bidirectional association.
Hesdorffer DC, Ishihara L, Mynepalli L, Webb DJ, Weil J, Hauser WA.
Ann Neurol. 2012 Aug;72(2):184-91.
PMID: 22887468.
64. Long-term use of Angiotensin receptor blockers and the risk of cancer.
Azoulay L, Assimes TL, Yin H, Bartels DB, Schiffrin EL, Suissa S.
PLoS One. 2012;7(12):e50893.
PMID: 23251399

65.
Bisphosphonates and risk of upper gastrointestinal cancer--a case control study using the General
Practice Research Database (GPRD).
Wright E, Schofield PT, Seed P, Molokhia M.
PLoS One. 2012;7(10):e47616.
PMID: 23112825
66. Pramipexole use and the risk of pneumonia.
Ernst P, Renoux C, Dell'aniello S, Suissa S.
BMC Neurol. 2012 Sep 29;12:113.
PMID: 23020246
67. Clinical features of bladder cancer in primary care.
Shephard EA, Stapley S, Neal RD, Rose P, Walter FM, Hamilton WT.
Br J Gen Pract. 2012 Sep;62(602):e598-604.
PMID: 22947580
68. Local estrogen therapy and risk of breast cancer recurrence among hormone-treated patients: a nested case-control study .
Le Ray I, Dell'Aniello S, Bonnetain F, Azoulay L, Suissa S.
Breast Cancer Res Treat. 2012 Sep;135(2):603-9.
PMID: 22903687.
69. Aspirin and other non-steroidal anti-inflammatory drug use and colorectal cancer survival: a cohort study.
Walker AJ, Grainge MJ, Card TR.
Br J Cancer. 2012 Oct 23;107(9):1602-7.
PMID: 23011483
70. The patterns of anticoagulation control and the risk of stroke, bleeding and mortality in patients with non-valvular atrial fibrillation. van den Ham HA, Klungel OH, Leufkens HG, van Staa TP.
J Thromb Haemost. 2013 Jan;11(1):107-15
PMID: 23088617.
71. Associations of Angiotensin Targeting Antihypertensive Drugs with Mortality and Hospitalization in
Primary Care Patients with Dementia .
Kehoe PG, Davies NM, Martin RM, Ben-Shlomo Y.
J Alzheimers Dis. 2013;33(4):999-1008
PMID: 23076074.
72. Comparing measures of multimorbidity to predict outcomes in primary care: a cross sectional study.
Brilleman SL, Salisbury C.
Fam Pract. 2013 Apr;30(2):172-8
PMID: 23045354.
73. Cluster randomized trial in the general practice research database: 2. Secondary prevention after first stroke (eCRT study): study protocol for a randomized controlled trial.
Dregan A, van Staa T, McDermott L, McCann G, Ashworth M, Charlton J, Wolfe C, Rudd A, Yardley L,
Gulliford MC.
Trials. 2012 Oct 3;13(1):181.
PMID: 23034059.
74. Post-marketing assessment of neuropsychiatric adverse events in influenza patients treated with oseltamivir: an updated review.
Toovey S, Prinssen EP, Rayner CR, Thakrar BT, Dutkowski R, Koerner A, Chu T,
Sirzen-Zelenskaya A, Britschgi M, Bansod S, Donner B.
Adv Ther. 2012 Oct;29(10):826-48.
PMID: 23054689.
75. Defining upper gastrointestinal bleeding from linked primary and secondary care data and the effect on

occurrence and 28 day mortality.
Crooks CJ, Card TR, West J.
BMC Health Serv Res. 2012 Nov 13;12(1):392.
PMID: 23148590.
76. Incidence of venous thromboembolism in patients with cancer - A cohort study using linked United
Kingdom databases.
Walker AJ, Card TR, West J, Crooks C, Grainge MJ.
Eur J Cancer. 2013 Apr;49(6):1404-13.
PMID: 23146958.
77. Regional and temporal variation in the treatment of rheumatoid arthritis across the UK: a descriptive register-based cohort study.
Edwards CJ, Campbell J, van Staa T, Arden NK.
BMJ Open. 2012 Nov 8;2(6).
PMID: 23144258.
78. Initial metformin or sulphonylurea exposure and cancer occurrence among patients with type 2 diabetes mellitus.
Qiu H, Rhoads GG, Berlin JA, Marcella SW, Demissie K.
Diabetes Obes Metab. 2013 Apr;15(4):349-57
PMID: 23137378.
79. Fracture risk with use of liver enzyme inducing antiepileptic drugs in people with active epilepsy: Cohort study using the General Practice Research Database.
Nicholas JM, Ridsdale L, Richardson MP, Grieve AP, Gulliford MC.
Seizure. 2013 Jan;22(1):37-42
PMID: 23127777.
80. Associations of type 2 diabetes and diabetes treatment with breast cancer risk and mortality: a population-based cohort study among British women.
Redaniel MT, Jeffreys M, May MT, Ben-Shlomo Y, Martin RM.
Cancer Causes Control. 2012 Nov;23(11):1785-95.
PMID: 22971998.
81. Antidepressant switching patterns in the treatment of major depressive disorder: a General Practice
Research Database (GPRD) Study.
Saragoussi D, Chollet J, Bineau S, Chalem Y, Milea D.
Int J Clin Pract. 2012 Nov;66(11):1079-87.
PMID: 23067031.
82. Incidence of urinary tract infection among patients with type 2 diabetes in the UK General Practice
Research Database (GPRD).
Hirji I, Guo Z, Andersson SW, Hammar N, Gomez-Caminero A.
J Diabetes Complications. 2012 Nov;26(6):513-6.
PMID: 22889712.
83. Metformin does not alter the risk of lung cancer: a case-control analysis.
Bodmer M, Becker C, Jick SS, Meier CR.
Lung Cancer. 2012 Nov;78(2):133-7.
PMID: 22959242.
84. Proton pump inhibitors and traditional nonsteroidal anti-inflammatory drugs and the risk of acute interstitial nephritis and acute kidney injury.
Leonard CE, Freeman CP, Newcomb CW, Reese PP, Herlim M, Bilker WB, Hennessy
S, Strom BL.
Pharmacoepidemiol Drug Saf. 2012 Nov;21(11):1155-72.
PMID: 22887960.
85. Comparison of prescription drug costs in the United States and the United kingdom, part 3:

methylphenidate.
Jick H, Wilson A, Wiggins P, Chamberlin DP.
Pharmacotherapy. 2012 Nov;32(11):970-3.
PMID: 23108719.
86. Representativeness of the dabigatran, apixaban and rivaroxaban clinical trial populations to real-world atrial fibrillation patients in the United Kingdom: a cross-sectional analysis using the General Practice
Research Database.
Lee S, Monz BU, Clemens A, Brueckmann M, Lip GY.
BMJ Open. 2012 Dec 14;2(6).
PMID: 23242482.
87. Cancer recording and mortality in the General Practice Research Database and linked cancer registries.
Boggon R, van Staa TP, Chapman M, Gallagher AM, Hammad TA, Richards MA.
Pharmacoepidemiol Drug Saf. 2013 Feb;22(2):168-75.
PMID: 23239282.
88. Omega-3 Fatty Acids and Mortality Outcome in Patients With and Without Type 2
Diabetes After Myocardial Infarction: A Retrospective, Matched-Cohort Study.
Poole CD, Halcox JP, Jenkins-Jones S, Carr ES, Schifflers MG, Ray KK, Currie CJ
Clin Ther. 2013 Jan;35(1):40-51
PMID: 23246017.
89. Opioid prescribing for cancer pain during the last 3 months of life: associated factors and 9-year trends in a nationwide United kingdom cohort study.
Higginson IJ, Gao W.
J Clin Oncol. 2012 Dec 10;30(35):4373-9.
PMID: 23109701.
90. Validation of Suicide and Self-harm records in the Clinical Practice Research
Datalink.
Thomas KH, Davies N, Metcalfe C, Windmeijer F, Martin RM, Gunnell D.
Br J Clin Pharmacol. 2013 Jul;76(1):145-57
PMID: 23216533.
91. Seizures in patients with Alzheimer's disease or vascular dementia: A population-based nested casecontrol analysis.
Imfeld P, Bodmer M, Schuerch M, Jick SS, Meier CR
Epilepsia. 2013 Apr;54(4):700-7
PMID: 23215680.
92. Data Resource Profile: Cardiovascular disease research using linked bespoke studies and electronic health records (CALIBER).
Denaxas SC, George J, Herrett E, Shah AD, Kalra D, Hingorani AD, Kivimaki M,
Timmis AD, Smeeth L, Hemingway H.
Int J Epidemiol. 2012 Dec;41(6):1625-38
PMID: 23220717.
93. Patient-related risk factors for fracture-healing complications in the United Kingdom General Practice
Research Database.
Hernandez RK, Do TP, Critchlow CW, Dent RE, Jick SS.
Acta Orthop. 2012 Dec;83(6):653-60.
PMID: 23140093.
94. Prescription of antiviral therapy after herpes zoster in general practice: who receives therapy?
Forbes HJ, Thomas SL, Smeeth L, Langan SM.
Br J Gen Pract.2012 Dec;62(605):808-14
PMID: 23211260
95 Survival of glioma and colorectal cancer patients using tricyclic antidepressants post-diagnosis.

Walker AJ, Grainge M, Bates TE, Card TR.
Cancer Causes Control. 2012 Dec;23(12):1959-64.
PMID: 23065071.
96. Epidemiology of castration resistant prostate cancer: A longitudinal analysis using a UK primary care database.
Hirst CJ, Cabrera C, Kirby M.
Cancer Epidemiol. 2012 Dec;36(6):e349-53.
PMID: 22910034.
97. Comorbidities in Perthes' disease: A case control study using the General Practice Research Database.
Perry DC, Bruce CE, Pope D, Dangerfield P, Platt MJ, Hall AJ.
J Bone Joint Surg Br. 2012 Dec;94(12):1684-9.
PMID: 23188912.
98. What next after metformin? A retrospective evaluation of the outcome of second-line, glucose-lowering therapies in people with type 2 diabetes.
Morgan CL, Poole CD, Evans M, Barnett AH, Jenkins-Jones S, Currie CJ.
J Clin Endocrinol Metab. 2012 Dec;97(12):4605-12.
PMID: 23076348.
99. Influenza Infection and Risk of Acute Myocardial Infarction in England and Wales: A CALIBER Self-
Controlled Case Series Study.
Warren-Gash C, Hayward AC, Hemingway H, Denaxas S, Thomas SL, Timmis AD,
Whitaker H, Smeeth L.
J Infect Dis. 2012 Dec;206(11):1652-9.
PMID: 23048170
100. Current prescribing of statins and persistence to statins following ACS in the UK: a MINAP/GPRD study.
Boggon R, Eaton S, Timmis A, Hemingway H, Gabriel Z, Minhas I, van Staa TP.
Br J Cardiol. 2012 Mar;19:24.

1.
2.
3.
4.
5.
6.
7.
8.
9.
Tricyclic antidepressants and the incidence of certain cancers: a study using the GPRD.
Walker AJ, Card T, Bates TE, Muir K.
Br J Cancer. 2011 Jan 4;104(1):193-7. Epub 2010 Nov 16.
PMID: 21081933
Antihypertensive treatment after first stroke in primary care: results from the General Practitioner
Research Database.
Toschke AM, Gulliford MC, Wolfe CD, Rudd AG, Heuschmann PU.
J Hypertens. 2011 Jan; 29(1):154-60.
PMID: 20842045
The use of antidepressants and the risk of haemorrhagic stroke: a nested case control study.
Douglas I, Smeeth L, Irvine D.
Br J Clin Pharmacol. 2011 Jan;71(1):116-20.
PMID: 21143507
Changes in hip fracture rate before and after total knee replacement due to osteoarthritis: a populationbased cohort study.
Prieto-Alhambra D, Javaid MK, Maskell J, Judge A, Nevitt M, Cooper C, Arden NK.
Ann Rheum Dis. 2011 Jan;70(1):134-8. Epub 2010 Oct 26.
PMID: 20980287
The effect of hip and knee arthroplasty on oral anti-inflammatory use and the relationship to body mass index: results from the UK general practice research database.
Bolland BJ, Culliford DJ, Maskell J, Latham JM, Dunlop DG, Arden NK.
Osteoarthritis Cartilage. 2011 Jan;19(1):29-36. Epub 2010 Oct 27.
PMID: 21034838
Concurrent drug use and the risk of perforated colonic diverticular disease: a population-based casecontrol study.
Humes DJ, Fleming KM, Spiller RC, West J.
Gut. 2011 Feb;60(2):219-24. Epub 2010 Oct 12.
PMID: 20940283
Epidemiology and impact of multimorbidity in primary care: a retrospective cohort study.
Salisbury C, Johnson L, Purdy S, Valderas JM, Montgomery AA.
Br J Gen Pract. 2011 Jan;61(582):e12-21.
PMID: 21401985
Utility of electronic patient records in primary care for stroke secondary prevention trials.
Dregan A, Toschke MA, Wolfe CD, Rudd A, Ashworth M, Gulliford MC; eCRT
Research team.
BMC Public Health. 2011 Feb 7;11:86.
PMID: 21299872
Comparing the General Practice Research Database and the UK Epilepsy and Pregnancy Register as tools for postmarketing teratogen surveillance: anticonvulsants and the risk of major congenital malformations.
Charlton RA, Weil JG, Cunnington MC, Ray S, de Vries CS.
Drug Saf. 2011 Feb 1;34(2):157-71.
PMID: 21247222.
Treatment persistence and cost-effectiveness of latanoprost/latanoprost-timolol, bimatoprost/bimatoprost-timolol, and travoprost/travoprost-timolol in glaucoma: an analysis based on the

10. United Kingdom general practitioner research database .
Lafuma A, Salmon JF, Robert J, Berdeaux G.
Clin Ophthalmol. 2011;5:361-7. Epub 2011 Mar 14.
PMID: 21468347
Parkinson's disease or Parkinson symptoms following seasonal influenza.
Toovey S, Jick SS, Meier CR.
11. Influenza Other Respi Viruses. 2011 Sep;5(5):328-33
PMID: 21668692.
12.
Primary care consultation behaviours of long-term, adult survivors of cancer in the UK.
Khan NF, Watson E, Rose PW.
Br J Gen Pract. 2011 Mar;61(584):197-9.
PMID: 21375904
Estimation of the rate of pelvic inflammatory disease diagnoses: trends in England, 2000-2008.
French CE, Hughes G, Nicholson A, Yung M, Ross JD, Williams T, Soldan K.
13. Sex Transm Dis. 2011 Mar;38(3):158-62.
PMID: 21311319
The relationship between neurological disease and bullous pemphigoid: a population-based case-control
14. study.
Langan SM, Groves RW, West J.
J Invest Dermatol. 2011 Mar;131(3):631-6. Epub 2010 Nov 18.
PMID: 21085189
15.
16.
17.
Effectiveness of inhaler types for real-world asthma management: retrospective observational study using the GPRD.
Price D, Haughney J, Sims E, Ali M, von Ziegenweidt J, Hillyer EV, Lee AJ, Chisholm A, Barnes N. J Asthma
Allergy. 2011; 4:37-47. Epub 2011 Apr 28.
PMID: 21698214
All-cause mortality in people with cirrhosis compared with the general population: a population-based cohort study.
Fleming KM, Aithal GP, Card TR, West J.
Liver Int. 2012 Jan;32(1):79-84
PMID: 21745279
Risk of venous thromboembolism in users of oral contraceptives containing drospirenone or levonorgestrel: nested case-control study based on UK General Practice Research Database.
Parkin L, Sharples K, Hernandez RK, Jick SS.
18.
BMJ. 2011 Apr 21;342:d2139.
PMID: 21511804
Higher Incidence of Common Diagnoses in Patients with Low Back Pain in Primary Care.
Bartholomeeusen S, Van Zundert J, Truyers C, Buntinx F, Paulus D.
Pain Pract. 2012 Jan;12(1):1-6
PMID: 21507198
Weight and glycaemic control in type 2 diabetes: what is the outcome of insulin initiation?
Watson L, Wilson BP, Alsop J, Kumar S.
19.
20.
Diabetes Obes Metab. 2011 Sep;13(9):823-31
PMID: 21481128
The use of atypical antipsychotics and the risk of breast cancer.
Azoulay L, Yin H, Renoux C, Suissa S.
Breast Cancer Res Treat. 2011 Sep;129(2):541-8.
PMID: 21479550
NSAID use and risk of Parkinson disease: a population-based case-control study.

21. Becker C, Jick SS, Meier CR.
Eur J Neurol. 2011 Nov;18(11):1336-42
PMID: 21457177
22.
Fracture risk before and after total hip replacement in patients with osteoarthritis: potential benefits of bisphosphonate use.
Prieto-Alhambra D, Javaid MK, Judge A, Maskell J, Kiran A, de Vries F, Cooper C, Arden NK.
Arthritis Rheum. 2011 Apr;63(4):992-1001.
PMID: 21452321
23.
Risk factors for intestinal ischaemia among patients registered in a UK primary care database: a nested case-control study.
Huerta C, Rivero E, Montoro MA, García-Rodriguez LA.
Aliment Pharmacol Ther. 2011 Apr;33(8):969-78. Epub 2011 Mar 1.
PMID: 21366637
24.
25.
Efficiency of glaucoma drug regulation in 5 European countries: a 1995-2006 longitudinal prescription analysis.
De Natale R, Le Pen C, Berdeaux G.
J Glaucoma. 2011 Apr-May;20(4):234-9.
PMID: 21682002
Epilepsy mortality and risk factors for death in epilepsy: a population-based study.
Ridsdale L, Charlton J, Ashworth M, Richardson MP, Gulliford MC.
Br J Gen Pract. 2011 May;61(586):271-8.
PMID: 21619751
26.
27.
28.
29.
30.
31.
Long-term effects of insulin glargine on the risk of breast cancer.
Suissa S, Azoulay L, Dell'aniello S, Evans M, Vora J, Pollak M.
Diabetologia. 2011 May 26.
PMID: 21614572
Cluster randomised trial in the General Practice Research Database: 1. Electronic decision support to reduce antibiotic prescribing in primary care (eCRT study).
Gulliford MC, van Staa T, McDermott L, Dregan A, McCann G, Ashworth M, Charlton J, Grieve AP, Little P,
Moore MV, Yardley L; electronic Cluster Randomised Trial Research Team eCRT Research Team.
Trials. 2011 May 10;12:115.
PMID: 21569237
Prescription patterns of analgesics in the last 3 months of life: a retrospective analysis of 10202 lung cancer patients.
Gao W, Gulliford M, Higginson IJ.
Br J Cancer. 2011 May 24;104(11):1704-10. Epub 2011 May 3.
PMID: 21540860
Diabetes mellitus and the risk of cholecystectomy.
Bodmer M, Brauchli YB, Jick SS, Meier CR.
Dig Liver Dis. 2011 Sep;43(9):742-7
PMID: 21616732
Body mass index and the incidence of influenza-associated pneumonia in a UK primary care cohort.
Blumentals WA, Nevitt A, Peng MM, Toovey S.
Influenza Other Respi Viruses. 2012 Jan;6(1):28-36
PMID: 21668664
Threshold haemoglobin levels and the prognosis of stable coronary disease: two new cohorts and a systematic review and meta-analysis.
Shah AD, Nicholas O, Timmis AD, Feder G, Abrams KR, Chen R, Hingorani AD, Hemingway H.
PLoS Med. 2011 May;8(5):e1000439. Epub 2011 May 31.
PMID: 21655315

32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
The risk of fracture in patients with multiple sclerosis: the UK general practice research database.
Bazelier MT, van Staa TP, Uitdehaag BM, Cooper C, Leufkens HG, Vestergaard P,
Bentzen J, de Vries F.
J Bone Miner Res. 2011 Sep;26(9):2271-9
PMID: 21557309
Role of acute diverticulitis in the development of complicated colonic diverticular disease and 1-year mortality after diagnosis in the UK: population-based cohort study.
Humes DJ, West J.
Gut. 2012 Jan;61(1):95-100.
PMID: 21551188
Use of tamoxifen and aromatase inhibitors in a large population-based cohort of women with breast cancer.
Huiart L, Dell'Aniello S, Suissa S.
Br J Cancer. 2011 May 10;104(10):1558-63. Epub 2011 Apr 26.
PMID: 21522148
Mortality rates and causes of death in children with epilepsy prescribed antiepileptic drugs: a retrospective cohort study using the UK General Practice Research Database.
Ackers R, Besag FM, Hughes E, Squier W, Murray ML, Wong IC.
Drug Saf. 2011 May 1;34(5):403-13.
PMID:21513363
Frequency and risk factors of gout flares in a large population-based cohort of incident gout.
Rothenbacher D, Primatesta P, Ferreira A, Cea-Soriano L, Rodríguez LA.
Rheumatology (Oxford). 2011 May;50(5):973-81. Epub 2011 Jan 12.
PMID: 21228059
Estimating the effect of nasal steroid treatment on repeat polypectomies: survival time analysis using the
General Practice Research Database.
Punekar YS, Ahmad A, Saleh HA.
Rhinology. 2011 Jun;49(2):190-4.
PMID:21743875
Academic impact of a public electronic health database: bibliometric analysis of studies using the general practice research database.
Chen YC, Wu JC, Haschler I, Majeed A, Chen TJ, Wetter T.
PLoS One. 2011;6(6):e21404. Epub 2011 Jun 22.
PMID: 21731733
Risk of cerebrovascular accident associated with use of antipsychotics: population-based case-control study.
Laredo L, Vargas E, Blasco AJ, Aguilar MD, Moreno A, Portolés A.
J Am Geriatr Soc. 2011 Jul;59(7):1182-7. Epub 2011 Jun 30.
PMID: 21718267
Menopausal hormone therapy and risk of gastrointestinal cancer: Nested case-control study within a prospective cohort, and meta-analysis.
Green J, Czanner G, Reeves G, Watson J, Wise L, Roddam A, Beral V.
Int J Cancer. 2012 May 15;130(10):2387-96
PMID: 21671473
Prescription patterns in asthma patients initiating salmeterol in UK general practice: a retrospective cohort study using the General Practice Research Database (GPRD).
DiSantostefano RL, Davis KJ.
Drug Saf. 2011 Jun 1;34(6):511-20.
PMID: 21585223

42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
Associations of Anti-Hypertensive Treatments with Alzheimer's Disease, Vascular Dementia, and
Other Dementias.
Davies NM, Kehoe PG, Ben-Shlomo Y, Martin RM.
J Alzheimers Dis. 2011;26(4):699-708
PMID: 21709373
The Relationship between Asthma and Depression in Primary Care Patients: A Historical Cohort and
Nested Case Control Study.
Walters P, Schofield P, Howard L, Ashworth M, Tylee A.
PLoS One. 2011;6(6):e20750. Epub 2011 Jun 15.
PMID: 21698276
Impact of rosiglitazone therapy on the lipid profile, glycemic control, and medication costs among type 2 diabetes patients.
Suh DC, Lee DH, McGuire M, Kim CM.
Curr Med Res Opin. 2011 Aug;27(8):1623-33. Epub 2011 Jun 22.
PMID: 21696266
Suboptimal gastroprotective coverage of NSAID use and the risk of upper gastrointestinal bleeding and ulcers: an observational study using three European databases. van Soest EM, Valkhoff VE, Mazzaglia G, Schade R, Molokhia M, Goldstein JL,
Hernández-Díaz S, Trifirò G, Dieleman JP, Kuipers EJ, Sturkenboom MC.
Gut. 2011 Dec;60(12):1650-9
PMID: 21636644
Gynaecological symptoms reported to primary care by women aged 15-29 years: a historical cohort study using electronic medical records, examining the potential for earlier diagnosis of cervical cancer.
Stapley S, Hamilton W.
Fam Pract. 2011 Dec;28(6):592-8
PMID: 21632969
Bisphosphonates and esophageal cancer-a pathway through the confusion.
Dixon WG, Solomon DH.
Nat Rev Rheumatol. 2011 Jun;7(6):369-72. Epub 2011 May 3.
PMID: 21537362
Use of antihypertensive medications and mortality of patients with autosomal dominant polycystic kidney disease: a population-based study.
Patch C, Charlton J, Roderick PJ, Gulliford MC.
Am J Kidney Dis. 2011 Jun;57(6):856-62. Epub 2011 Apr 2.
PMID: 21458899
Increased Risk of Myocardial Infarction Among Patients with Ulcerative Colitis or Crohn's Disease.
Osterman MT, Yang YX, Brensinger C, Forde KA, Lichtenstein GR, Lewis JD. No
Clin Gastroenterol Hepatol. 2011 Oct;9(10):875-80.
PMID: 21749853
Evidence-based (S3) guideline on topical corticosteroids in pregnancy.
Chi CC, Kirtschig G, Aberer W, Gabbud JP, Lipozenčić J, Kárpáti S, Haustein
UF, Zuberbier T, Wojnarowska F. Br J
Br J Dermatol. 2011 Nov;165(5):943-52
PMID: 21729030
Validity of diagnoses in the General Practice Research Database.
Herrett EL, Thomas SL, Smeeth L.
Br J Gen Pract. 2011 Jul;61(588):438-9.
PMID: 21722461
Statin use and risk of first-time psoriasis diagnosis.

52. Brauchli YB, Jick SS, Meier CR.
J Am Acad Dermatol. 2011 Jul;65(1):77-83. Epub 2011 May 6.
53.
PMID: 21529997
Trends in Type 1 diabetes incidence in the UK in 0- to 14-year-olds and in 15- to 34-year-olds, 1991-2008.
Imkampe AK, Gulliford MC.
Diabet Med. 2011 Jul;28(7):811-4.
PMID: 21395679
54.
Predictors of incident atrial fibrillation and influence of medications: a retrospective case-control study.
Hodgkinson JA, Taylor CJ, Hobbs FD.
Br J Gen Pract. 2011 Jun;61(587):e353-61.
PMID: 21801515
55.
56.
57.
Comprehensive comparison of drug prescribing in the United States and United Kingdom.
Parkin L, Hagberg KW, Jick H.
Pharmacotherapy. 2011 Jul;31(7):623-9.
PMID: 21923448.
Use of metformin and the risk of ovarian cancer: A case-control analysis.
Bodmer M, Becker C, Meier C, Jick SS, Meier CR.
Gynecol Oncol. 2011 Nov;123(2):200-4.
PMID: 21802715.
Thiazolidinediones and the risk of incident congestive heart failure among patients with type 2 diabetes mellitus.
Filion KB, Joseph L, Boivin JF, Suissa S, Brophy JM.
58.
Pharmacoepidemiol Drug Saf. 2011 Aug;20(8):785-96. doi: 10.1002/pds.2165. Epub 2011 Jun 13.
PMID: 21671441
Attributable risk estimate of severe psoriasis on major cardiovascular events.
Mehta NN, Yu Y, Pinnelas R, Krishnamoorthy P, Shin DB, Troxel AB, Gelfand JM.
Am J Med. 2011 Aug;124(8):775.e1-6.
PMID: 21787906
Thiazolidinediones and the risk of incident congestive heart failure among patients with type 2 diabetes
59.
60. mellitus.
Filion KB, Joseph L, Boivin JF, Suissa S, Brophy JM.
Pharmacoepidemiol Drug Saf. 2011 Aug;20(8):785-96. doi: 10.1002/pds.2165. Epub 2011 Jun 13.
PMID: 21671441
Antibacterial Drugs and the Risk of Community-Associated Methicillin-Resistant Staphylococcus aureus in Children.
Schneider-Lindner V, Quach C, Hanley JA, Suissa S.
Arch Pediatr Adolesc Med. 2011 Dec;165(12):1107-14
PMID: 21810624
61.
62.
Association of practice size and pay-for-performance incentives with the quality of diabetes management in primary care.
Vamos EP, Pape UJ, Bottle A, Hamilton FL, Curcin V, Ng A, Molokhia M, Car J, Majeed A, Millett C.
CMAJ. 2011 Sep 6;183(12):E809-16. Epub 2011 Aug 2.
PMID: 21810950
Genital warts and cost of care in England.
Desai S, Wetten S, Woodhall SC, Peters L, Hughes G, Soldan K.
Sex Transm Infect. 2011 Oct;87(6):464-8. Epub 2011 Aug 3.
PMID: 21813567
An increased risk of urinary tract infection precedes development of primary biliary cirrhosis.
Varyani FK, West J, Card TR.

63. BMC Gastroenterol. 2011 Aug 26;11:95.
PMID: 21871059
64.
Androgen-Deprivation Therapy and the Risk of Stroke in Patients With Prostate Cancer.
Azoulay L, Yin H, Benayoun S, Renoux C, Boivin JF, Suissa S.
Eur Urol. 2011 Dec;60(6):1244-50
PMID: 21908097
65.
66.
Clopidogrel discontinuation after acute coronary syndromes: frequency, predictors and associations with death and myocardial infarction--a hospital registry-primary care linked cohort (MINAP-GPRD).
Boggon R, van Staa TP, Timmis A, Hemingway H, Ray KK, Begg A, Emmas C, Fox KA.
Eur Heart J. 2011 Oct;32(19):2376-86. Epub 2011 Aug 29.
PMID: 21875855
Angiotensin converting enzyme inhibitors and hepatocellular carcinoma incidence in the General Practice
Research Database.
Walker AJ, West J, Grainge MJ, Card TR.
Cancer Causes Control. 2011 Dec;22(12):1743-7
PMID: 21909951.
Mortality in children and adolescents prescribed antipsychotic medication: a retrospective cohort study
67.
68. using the UK general practice research database.
Rani FA, Byrne P, Cranswick N, Murray ML, Wong IC.
Drug Saf. 2011 Sep 1;34(9):773-81. doi: 10.2165/11591120-000000000-00000.
PMID: 21830839
Risks of stroke and mortality associated with suboptimal anticoagulation in atrial fibrillation patients.
Gallagher AM, Setakis E, Plumb JM, Clemens A, van Staa TP.
Thromb Haemost. 2011 Nov;106(5):968-77
PMID: 21901239
69.
70.
Identification of esophageal cancer in the General Practice Research Database.
Walker AM.
Pharmacoepidemiol Drug Saf. 2011 Nov;20(11):1159-67
PMID: 21928362.
An evaluation of Birmingham Own Health® telephone care management service among patients with poorly controlled diabetes. a retrospective comparison with the General Practice Research Database.
Jordan RE, Lancashire RJ, Adab P.
BMC Public Health.
2011 Sep 19;11:707.
PMID: 21929804
Long-term use of fluticasone propionate/salmeterol fixed-dose combination and incidence of cataracts and glaucoma among chronic obstructive pulmonary disease patients in the UK General Practice Research
71.
72.
73.
Database.
Miller DP, Watkins SE, Sampson T, Davis KJ.
Int J Chron Obstruct Pulmon Dis.
2011;6:467-76. Epub 2011 Sep 16.
PMID: 22003292
Persistence with osteoporosis medications among postmenopausal women in the UK General
Practice Research Database.
Li L, Roddam A, Gitlin M, Taylor A, Shepherd S, Shearer A, Jick S.
Menopause. 2012 Jan;19(1):33-40
PMID: 21926926.
Use of statins is associated with an increased risk of rheumatoid arthritis. de Jong HJ, Klungel OH, van Dijk L, Vandebriel RJ, Leufkens HG, van der Laan
J, Tervaert JW, van Loveren H.
Ann Rheum Dis. 2012 May;71(5):648-54

74.
75.
76.
77.
78.
89.
80.
81.
82.
83.
PMID: 21979000.
Seasonality of medical contacts in school-aged children with asthma: association with school holidays.
Julious SA, Campbell MJ, Bianchi SM, Murray-Thomas T.
Public Health. 2011 Nov;125(11):769-76. Epub 2011 Oct 28.
PMID: 22036686.
Risk of convulsions in children after monovalent H1N1 (2009) and trivalent influenza vaccines: a database study.
Stowe J, Andrews N, Bryan P, Seabroke S, Miller E.
Vaccine. 2011 Nov 28;29(51):9467-72. Epub 2011 Oct 20.
PMID: 22019757.
Risk of cataract and glaucoma in patients with multiple sclerosis.
Bazelier MT, Mueller-Schotte S, Leufkens HG, Uitdehaag BM, van Staa T, de Vries F.
Mult Scler. 2012 May;18(5):628-38
PMID: 22025330.
Risk of acute renal failure in patients with Type diabetes mellitus.
Girman CJ, Kou TD, Brodovicz K, Alexander CM, O'Neill EA, Engel S, Williams-Herman DE, Katz L.
Diabet Med. 2012 May;29(5):614-21
PMID: 22017349.
Glucose-lowering agents and the patterns of risk for cancer: a study with the General Practice Research
Database and secondary care data van Staa TP, Patel D, Gallagher AM, de Bruin ML.
Diabetologia. 2012 Mar;55(3):654-65.
PMID: 22127412.
The LUCK study: Laxative Usage in patients with GP-diagnosed Constipation in the UK, within the general population and in pregnancy. An epidemiological study using the General Practice Research
Database (GPRD).
Shafe AC, Lee S, Dalrymple JS, Whorwell PJ.
Therap Adv Gastroenterol. 2011 Nov;4(6):343-63.
PMID: 22043228
The London low emission zone baseline study.
Kelly F, Armstrong B, Atkinson R, Anderson HR, Barratt B, Beevers S, Cook D,
Green D, Derwent D, Mudway I, Wilkinson P; HEI Health Review Committee.
Res Rep Health Eff Inst. 2011 Nov;(163):3-79.
PMID: 22315924.
Cancer risk in people with epilepsy using valproate-sodium.
Singh G, Bell GS, Driever PH, Sander JW.
Acta Neurol Scand. 2012 Apr;125(4):234-40
PMID: 22077648.
Long-term health outcomes in a British cohort of breast, colorectal and prostate cancer survivors: a database study.
Khan NF, Mant D, Carpenter L, Forman D, Rose PW.
Br J Cancer. 2011 Nov 8;105 Suppl 1:S29-37. doi: 10.1038/bjc.2011.420.
PMID: 22048030
Androgen deprivation therapy and the risk of coronary heart disease and heart failure in patients with prostate cancer: a nested case-control study in UK primary care.
Martín-Merino E, Johansson S, Morris T, García Rodríguez LA.
Drug Saf. 2011 Nov 1;34(11):1061-77. doi: 10.2165/11594540-000000000-00000.
PMID: 21981434.

84.
85.
86.
87.
88.
89.
90.
91.
92.
93.
94.
Factors associated with uptake of seasonal and pandemic influenza vaccine among clinical risk groups in the UK: An analysis using the General Practice Research Database .
Sammon CJ, McGrogan A, Snowball J, de Vries CS.
Vaccine. 2012 Mar 23;30(14):2483-9.
PMID: 22133511.
Perthes' disease in the UK: Geographic and temporal trends in incidence reflecting deprivation inequalities in childhood.
Perry DC, Bruce CE, Pope D, Dangerfield P, Platt MJ, Hall AJ.
Arthritis Rheum. 2012 May;64(5):1673-9
PMID: 22143958.
Prevalence of diagnosed adult immune thrombocytopenia in the United kingdom.
Bennett D, Hodgson ME, Shukla A, Logie JW.
Adv Ther. 2011 Dec;28(12):1096-104. Epub 2011 Dec 1.
PMID: 22139790.
Risk of cancer in patients exposed to gabapentin in two electronic medical record
Systems.
Irizarry MC, Webb DJ, Boudiaf N, Logie J, Habel LA, Udaltsova N, Friedman GD.
Pharmacoepidemiol Drug Saf. 2012 Feb;21(2):214-25. doi:10.1002/pds.2266. Epub 2011 Dec 6. PMID:
22144034.
Risk of Tuberculosis in Pregnancy: A National, Primary Care Based Cohort and Self-Controlled Case
Series Study.
Zenner D, Kruijshaar ME, Andrews N, Abubakar I.
Am J Respir Crit Care Med. 2012 Apr 1;185(7):779-84
PMID: 22161161.
Risk of herpes zoster in patients prescribed inhaled corticosteroids: a cohort study.
Ernst P, Dell'aniello S, Mikaeloff Y, Suissa S.
BMC Pulm Med. 2011 Dec 16;11:59.
PMID: 22177425
Potential application of item-response theory to interpretation of medical codes in electronic patient records.
Dregan A, Grieve A, van Staa T, Gulliford MC; the eCRT Research Team.
BMC Med Res Methodol. 2011 Dec 16;11(1):168.
PMID: 22176509
Risk of death and cardiovascular outcomes with thiazolidinediones: a study with the general practice research database and secondary care data.
Gallagher AM, Smeeth L, Seabroke S, Leufkens HG, van Staa TP.
PLoS One. 2011;6(12):e28157
PMID: 22164237
Exposure to oral bisphosphonates and risk of cancer.
Cardwell CR, Abnet CC, Veal P, Hughes CM, Cantwell MM, Murray LJ.
Int J Cancer. 2012 Sep 1;131(5):E717-25
PMID: 22161552.
The positivity assumption and marginal structural models: the example of warfarin use and risk of bleeding.
Platt RW, Delaney JA, Suissa S.
Eur J Epidemiol. 2012 Feb;27(2):77-83.
PMID: 22160333.
Association between bisphosphonate use and implant survival after primary total arthroplasty of the knee or hip: population based retrospective cohort study.
Prieto-Alhambra D, Javaid MK, Judge A, Murray D, Carr A, Cooper C, Arden NK.

BMJ. 2011 Dec 6;343:d7222. doi: 10.1136/bmj.d7222.
PMID: 22147909
1.
2.
3.
4.
5.
6.
7.
8.
9.
Validation and validity of diagnoses in the General Practice Research Database: a systematic review.
Herrett E, Thomas SL, Schoonen WM, Smeeth L, Hall AJ.Br J
Clin Pharmacol. 2010 Jan; 69(1):4-14.
PMID: 20078607
Exploring differential prescribing between anti-epileptic drugs in epilepsy patients with a history of mood disorders.
Ishihara L, Webb DJ, Irizarry M, Weil J.
Pharmacoepidemiol Drug Saf. 2010 Mar;19(3):289-95
PMID: 20077522
Combination therapy with sulfonylureas and metformin and the prevention of death in type 2 diabetes: a nested case-control study.
Azoulay L, Schneider-Lindner V, Dell'aniello S, Schiffrin A, Suissa S.
Pharmacoepidemiol Drug Saf. 2010 Apr;19(4):335-42
PMID: 20052677
Adaptation and validation of the Charlson Index for Read/OXMIS coded databases.
Khan NF, Perera R, Harper S, Rose PW.
BMC Fam Pract. 2010 Jan 5;11(1):1.
PMID: 20051110
Phynx: an open source software solution supporting data management and web-based patient-level data review for drug safety studies in the general practice research database and other health care databases.
Egbring M, Kullak-Ublick GA, Russmann S.
Pharmacoepidemiol Drug Saf. 2010 Jan;19(1):38-44.
PMID: 19777533
Risk of Cancer in Inflammatory Bowel Disease Treated With Azathioprine: A UK Population-Based Case-
Control Study.
Armstrong RG, West J, Card TR.
Am J Gastroenterol. 2010 Jul;105(7):1604-9.
PubMed PMID: 20104215
Risk for incident atrial fibrillation in patients who receive antihypertensive drugs: a nested case-control study.
Schaer BA, Schneider C, Jick SS, Conen D, Osswald S, Meier CR.
Ann Intern Med. 2010 Jan 19;152 (2):78-84.
PMID: 20083826
Temporal trends in hip and knee replacement in the United Kingdom: 1991 to 2006.
Culliford DJ, Maskell J, Beard DJ, Murray DW, Price AJ, Arden NK.
J Bone Joint Surg Br. 2010 Jan;92(1):130-5.
PMID: 20044691
Association between dyslipidemia and vascular events in patients treated with statins: Report from the UK
General Practice Research Database.
Sazonov V, Beetsch J, Phatak H, Wentworth C, Evans M.

10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
Atherosclerosis. 2010 Jan;208(1):210-216. Epub 2009 Sep 20.
PMID: 19766999
Association of smoking with amyotrophic lateral sclerosis risk and survival in men and women: a prospective study.
Alonso A, Logroscino G, Jick SS, Hernán MA.
BMC Neurol. 2010 Jan 14;10:6.
PMID: 20074360
The identification of pregnancies within the general practice research database.
Devine S, West S, Andrews E, Tennis P, Hammad TA, Eaton S, Thorp J, Olshan A.
Pharmacoepidemiol Drug Saf. 2010 Jan;19(1):45-50.
PMID: 19823973
Survival as a function of HbA(1c) in people with type 2 diabetes: a retrospective cohort study.
Currie CJ, Peters JR, Tynan A, Evans M, Heine RJ, Bracco OL, Zagar T, Poole CD.
Lancet. 2010 Feb 6;375(9713):481-9.
PMID: 20110121
Use of venlafaxine compared with other antidepressants and the risk of sudden cardiac death or near death: a nested case-control study.
Martinez C, Assimes TL, Mines D, Dell'aniello S, Suissa S.
BMJ. 2010 Feb 5;340:c249.
PMID: 20139216
Thromboembolic events among adult patients with primary immune thrombocytopenia (ITP) in the
United Kingdom General Practice Research Database.
Sarpatwari A, Bennett D, Logie JW, Shukla A, Beach KJ, Newland A, Sanderson S, Provan D.
Haematologica. 2010 Jul;95(7):1167-75
PMID: 20145266
Prospective drug safety monitoring using the UK primary-care General Practice Research Database: theoretical framework, feasibility analysis and extrapolation to future scenarios.
Johansson S, Wallander MA, de Abajo FJ, García Rodríguez LA.
Drug Saf. 2010 Mar 1;33(3):223-32.
PMID: 20158286
Are GPs under-investigating older patients presenting with symptoms of ovarian cancer? Observational study using General Practice Research Database.
Tate AR, Nicholson A, Cassell JA.
Br J Cancer. 2010 Mar 16;102(6):947-51.
PMID: 20197770
Mortality and cancer in patients with new musculoskeletal episodes: a cohort study.
Jordan KP, Croft P.
Br J Gen Pract. 2010 Mar;60(572):e105-11.
PMID: 20202352
Validity of diagnostic coding within the General Practice Research Database: a systematic review.
Khan NF, Harrison SE, Rose PW.
Br J Gen Pract. 2010 Mar; 60(572):e128-36.
PMID: 20202356
Hormone replacement therapy and the risk of venous thromboembolism: population-based study.
Renoux C, Dell'aniello S, Suissa S.
J Thromb Haemost. 2010 May;8(5):979-86.
PMID: 20230416
Determining patient characteristics for decision analysis support systems using anonymized electronic

20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30. patient records.
Frisher M, Short D, Bashford J.
Health Informatics J. 2010 Mar;16(1):49-57.
PMID: 20413412
Long-acting beta2-agonists in adult asthma and the pattern of risk of death and severe asthma outcomes: a study with the General Practice Research Database. de Vries F, Setakis E, Zhang B, van Staa TP.
Eur Respir J. 2010 Sep;36(3):494-502
PMID: 20351036
Declining 1-year case-fatality of stroke and increasing coverage of vascular risk management:populationbased cohort study.
Gulliford MC, Charlton J, Rudd A, Wolfe CD, Toschke AM.
J Neurol Neurosurg Psychiatry. 2010 Apr;81(4):416-22.
PMID: 20176596
Chronic obstructive pulmonary disease and the risk of cardiovascular diseases.
Schneider C, Bothner U, Jick SS, Meier CR.
Eur J Epidemiol. 2010 Apr;25(4):253-60.
PMID: 20191376
Non-steroidal anti-inflammatory drugs and pancreatic cancer risk: a nested case-control study.
Bradley MC, Hughes CM, Cantwell MM, Napolitano G, Murray LJ.
Br J Cancer. 2010 Apr 27;102(9):1415-21.
PMID: 20372155
Epidemiology of paediatric immune thrombocytopenia in the General Practice Research Database.
Yong M, Schoonen WM, Li L, Kanas G, Coalson J, Mowat F, Fryzek J, Kaye JA.
Br J Haematol. 2010 Jun;149(6):855-64.
PMID: 20377590
Healthcare expenditure in severely depressed patients treated with escitalopram, generic SSRIs or venlafaxine in the UK.
Wade AG, Saragoussi D, Despiégel N, François C, Guelfucci F, Toumi M.
Curr Med Res Opin. 2010 May;26(5):1161-70.
PMID: 20297951
Laboratory monitoring and adverse patient outcomes with antihypertensive therapy in primary care.
McDowell SE, Coleman JJ, Evans SJ, Gill PS, Ferner RE
Pharmacoepidemiol Drug Saf. 2010 May;19(5):482-9.
PMID: 20306453
Prescribing patterns of asthma controller therapy for children in UK primary care: a cross-sectional observational study.
Thomas M, Murray-Thomas T, Fan T, Williams T, Taylor S.
BMC Pulm Med. 2010 May 14;10:29.
PMID: 20470409
Measles in the United Kingdom 1990-2008 and the effectiveness of measles vaccines.
Jick H, Hagberg KW.
Vaccine. 2010 Jun 23;28(29):4588-92.
PMID: 20470793
Rhythm control agents and adverse events in patients with atrial fibrillation.
Taylor CJ, Hodgkinson J, Hobbs FD.
Int J Clin Pract. 2010 Jul;64(8):1069-75
PMID: 20487051
Heart failure, myocardial infarction, lung cancer and death in COPD patients: A UK primary care study.

31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
García Rodríguez LA, Wallander MA, Martín-Merino E, Johansson S.
Respir Med. 2010 Nov;104(11):1691-9.
PMID: 20483577
Long-term metformin use is associated with decreased risk of breast cancer.
Bodmer M, Meier C, Krähenbühl S, Jick SS, Meier CR.
Diabetes Care. 2010 Jun;33(6):1304-8.
PMID: 20299480
Treatment of type 2 diabetes and outcomes in patients with heart failure: a nested case-control study from the U.K. General Practice Research Database.
MacDonald MR, Eurich DT, Majumdar SR, Lewsey JD, Bhagra S, Jhund PS, Petrie MC, McMurray JJ, Petrie
JR, McAlister FA.
Diabetes Care. 2010 Jun;33(6):1213-8.
PMID: 20299488
Reflux disease, gastrointestinal ulcer or weight loss in patients with COPD.
Schneider C, Jick SS, Bothner U, Meier CR.
COPD. 2010 Jun;7(3):172-8.
PMID: 20486815
Transdermal and oral hormone replacement therapy and the risk of stroke: a nested case-control study.
Renoux C, Dell'aniello S, Garbe E, Suissa S.
BMJ.2010 Jun 3;340:c2519.
PMID: 20525678
Menopause-related workload in general practice 1996-2005: a retrospective study in the UK.
Iversen L, Delaney EK, Hannaford PC, Black C.
Fam Pract. 2010 Oct;27(5):499-506.
PMID: 20530133.
Oversight: a retrospective study of biochemical monitoring in patients beginning antihypertensive drug treatment in primary care.
Coleman JJ, McDowell SE, Evans SJ, Gill PS, Ferner RE.
Br J Clin Pharmacol. 2010 Jul;70(1):109-17.
PMID: 20642553
Use of antiepileptic drugs in epilepsy and the risk of self-harm or suicidal behavior.
Andersohn F, Schade R, Willich SN, Garbe E.
Neurology. 2010 Jul 27;75(4):335-40.
PMID: 20660863
Risk of incident depression in patients with Parkinson disease in the UK.
Becker C, Brobert GP, Johansson S, Jick SS, Meier CR.
Eur J Neurol. 2011 Mar;18(3):448-53.
PMID: 20722714
The risk of depression, anxiety, and suicidality in patients with psoriasis: a population-based cohort study.
Kurd SK, Troxel AB, Crits-Christoph P, Gelfand JM.
Arch Dermatol. 2010 Aug;146(8):891-5.
PMID: 20713823
Exposure to oral bisphosphonates and risk of esophageal cancer.
Cardwell CR, Abnet CC, Cantwell MM, Murray LJ.
JAMA. 2010 Aug 11;304(6):657-63.
PMID: 20699457
Risk of ischemic stroke in patients with Crohn's disease: a population-based nested case-control study.
Andersohn F, Waring M, Garbe E.
Inflamm Bowel Dis.2010 Aug;16(8):1387-92.

43.
44.
45.
46.
47.
48.
49.
50.
51,
52,
53.
PMID: 20014016
Concomitant use of ibuprofen and paracetamol and the risk of major clinical safety outcomes. de Vries F, Setakis E, van Staa TP.
Br J Clin Pharmacol. 2010 Sep;70(3):429-38.
PMID: 20716244
Identifying major congenital malformations in the UK General Practice Research Database (GPRD): a study reporting on the sensitivity and added value of photocopied medical records and free text in the
GPRD.
Charlton RA, Weil JG, Cunnington MC, de Vries CS. Drug Saf. 2010 Sep 1;33(9):741-50.
PMID: 20701407
Hospitalization risk in a type 2 diabetes cohort.
Ng E, McGrail KM, Johnson JA.
Health Rep. 2010 Sep;21(3):29-35.
PMID: 20973431
Concurrent use of tamoxifen with CYP2D6 inhibitors and the risk of breast cancer recurrence.
Azoulay L, Dell'aniello S, Huiart L, du Fort GG, Suissa S. Breast
Breast Cancer Res Treat. 2011 Apr;126(3):695-703
PMID: 20848186
Quality of care for chronic diseases in a British cohort of long-term cancer survivors.
Khan NF, Mant D, Rose PW. Ann Fam Med. 2010 Sep-Oct;8(5):418-24.
PMID: 20843883
Oral bisphosphonates and risk of cancer of oesophagus, stomach, and colorectum: case-control analysis within a UK primary care cohort.
Green J, Czanner G, Reeves G, Watson J, Wise L, Beral V.
BMJ. 2010 Sep 1;341:c4444.
PMID: 20813820
Identifying major congenital malformations in the UK General Practice Research Database (GPRD): a study reporting on the sensitivity and added value of photocopied medical records and free text in the
GPRD.
Charlton RA, Weil JG, Cunnington MC, de Vries CS.
Drug Saf. 2010 Sep 1;33(9):741-50.
PMID: 20701407
Patients with type 2 diabetes mellitus have higher risk for acute pancreatitis compared with those without diabetes.
Girman CJ, Kou TD, Cai B, Alexander CM, O'Neill EA, Williams-Herman DE, Katz L.
Diabetes Obes Metab. 2010 Sep;12(9):766-71.
PMID: 20649628
Cause-specific mortality in patients with severe psoriasis: a population-based cohort study in the U.K.
Abuabara K, Azfar RS, Shin DB, Neimann AL, Troxel AB, Gelfand JM.
Br J Dermatol. 2010 Sep;163(3):586-92.
PMID: 20633008
A comparison of risk stratification schema for stroke in 79884 atrial fibrillation patients in general practice.
Van Staa TP, Setakis E, Di Tanna GL, Lane DA, Lip GY.
J Thromb Haemost. 2011 Jan;9(1):39-48
PMID: 21029359.
Risk of death during and after opiate substitution treatment in primary care: prospective observational study in UK General Practice Research Database.
Cornish R, Macleod J, Strang J, Vickerman P, Hickman M.

54.
55.
56.
57.
58.
59.
60.
61.
62,
63.
64.
BMJ. 2010 Oct 26;341:c5475.
PMID: 20978062
Management of first-episode pelvic inflammatory disease in primary care: results from a large UK primary care database.
Nicholson A, Rait G, Murray-Thomas T, Hughes G, Mercer CH, Cassell J.
Br J Gen Pract. 2010 Oct;60(579):e395-406.
PMID: 20883614
Management of epididymo-orchitis in primary care: results from a large UK primary care database.
Nicholson A, Rait G, Murray-Thomas T, Hughes G, Mercer CH, Cassell J.
Br J Gen Pract. 2010 Oct;60(579):e407-22.
PMID: 20883615
Influenza vaccination, pneumococcal vaccination and risk of acute myocardial infarction: matched casecontrol study.
Siriwardena AN, Gwini SM, Coupland CA.
CMAJ. 2010 Oct 19;182(15):1617-23. Epub 2010 Sep 20.
PMID: 20855479
Mortality in Wegener's granulomatosis: a bimodal pattern.
Luqmani R, Suppiah R, Edwards CJ, Phillip R, Maskell J, Culliford D, Jayne D, Morishita K, Arden N.
Rheumatology (Oxford). 2011 Apr;50(4):697-702.
PMID: 21112869
Use of depot medroxyprogesterone acetate and fracture risk.
Meier C, Brauchli YB, Jick SS, Kraenzlin ME, Meier CR.
J Clin Endocrinol Metab. 2010 Nov;95(11):4909-16. Epub 2010 Aug 4.
PMID: 20685865
Statins and pancreatic cancer risk: a nested case-control study.
Bradley MC, Hughes CM, Cantwell MM, Murray LJ.
Cancer Causes Control. 2010 Dec;21(12):2093-100.
PMID: 20697797.
Safety of Topical Corticosteroids in Pregnancy: A Population-Based Cohort Study.
Chi CC, Mayon-White RT, Wojnarowska FT.
J Invest Dermatol. 2011 Apr;131(4):884-91
PMID: 21191410
Developing and testing search strategies to identify patients with active seasonal allergic rhinitis in general practice.
Hammersley V, Flint R, Pinnock H, Sheikh A.
Prim Care Respir J. 2011 Mar;20(1):71-4.
PMID: 21190011
Epidemiology of paediatric immune thrombocytopenia in the General Practice Research Database.
Yong M, Schoonen WM, Li L, Kanas G, Coalson J, Mowat F, Fryzek J, Kaye JA.
Br J Haematol. 2010 Jun;149(6):855-64. Epub 2010 Apr 4.
PMID: 20377590
Secular trends of antibacterial prescribing in UK paediatric primary care.
Schneider-Lindner V, Quach C, Hanley JA, Suissa S.
J Antimicrob Chemother. 2011 Feb;66(2):424-33
PMID: 21172784
Long-term use of fluticasone propionate/salmeterol fixed-dose combination and incidence of nonvertebral fractures among patients with COPD in the UK General Practice Research Database.
Miller DP, Watkins SE, Sampson T, Davis KJ.
Phys Sportsmed. 2010 Dec;38(4):19-27.

65.
66.
67.
68.
69.
1.
2.
3.
4.
5.
PMID: 21150138
Metformin and the incidence of prostate cancer in patients with type 2 diabetes.
Azoulay L, Dell'aniello S, Gagnon B, Pollak MN, Suissa S.
Cancer Epidemiol Biomarkers Prev. 2011 Feb;20(2):337-44.
PMID: 21148757
Impact of Treatment Success on Health Service Use and Cost in Depression: Longitudinal Database
Analysis.
Byford S, Barrett B, Despiégel N, Wade A.
Pharmacoeconomics. 2011 Feb;29(2):157-70.
PMID: 21142289
Effectiveness of influenza vaccination in the United kingdom, 1996-2007.
Jick H, Hagberg KW.
Pharmacotherapy. 2010 Dec;30(12):1199-206.
PMID: 21114386
The rate of decompensation and clinical progression of disease in people with cirrhosis: a cohort study.
Fleming KM, Aithal GP, Card TR, West J. Aliment
Pharmacol Ther. 2010 Dec;32(11-12):1343-50. Epub 2010 Oct 4.
PMID: 21050236
Consulting and prescribing behaviour for anxiety and depression in long-term survivors of cancer in the
UK.
Khan NF, Ward AM, Watson E, Rose PW.
Eur J Cancer. 2010 Dec;46(18):3339-44.Epub 2010 Aug 18.
PMID: 20727734
The epidemiology of haemochromatosis: a population-based study.
Crooks CJ, West J, Solaymani-Dodaran M, Card TR.
Aliment Pharmacol Ther. 2009 Jan 15;29(2):183-92. Epub 2008 Oct 20.
PMID: 18945251
The risk of venous thromboembolism associated with the use of tranexamic acid and other drugs used to treat menorrhagia: a case-control study using the General Practice Research Database.
Sundström A, Seaman H, Kieler H, Alfredsson L.
BJOG. 2009 Jan;116(1):91-7. Epub 2008 Nov 11.
PMID: 19016686
Inhaled corticosteroids for asthma: impact of practice level device switching on asthma control.
Thomas M, Price D, Chrystyn H, Lloyd A, Williams AE, von Ziegenweidt J.
BMC Pulm Med. 2009 Jan 2;9:1
PMID: 19121204
Psoriasis and risk of incident myocardial infarction, stroke or transient ischaemic attack: an inception cohort study with a nested case-control analysis.
Brauchli YB, Jick SS, Miret M, Meier CR.
Br J Dermatol. 2009 May;160(5):1048-56.
PMID: 19210501
Prescribing trends in asthma: a longitudinal observational study .
Turner S, Thomas M, von Ziegenweidt J, Price D.
Arch Dis Child. 2009 Jan;94(1):16-22. Epub 2008 Aug 13.

6.
9.
7.
8.
10.
11.
12.
13.
14.
15.
PMID: 18701558
The potential effects on fracture outcomes of improvements in persistence and compliance with bisphosphonates.
Rietbrock S, Olson M, van Staa TP.
QJM. 2009 Jan;102(1):35-42. Epub 2008 Oct 8.
PMID: 18842684
Traditional versus marginal structural models to estimate the effectiveness of beta-blocker use on mortality after myocardial infarction.
Delaney JA, Daskalopoulou SS, Suissa S.
Pharmacoepidemiol Drug Saf. 2009 Jan;18(1):1-6.
PMID: 18949804
Study of adverse outcomes in women using testosterone therapy. van Staa TP, Sprafka JM.
Maturitas. 2009 Jan 20;62(1):76-80. Epub 2008 Dec 24.
PMID: 19108962
Use of primary care electronic medical record database in drug efficacy research on cardiovascular outcomes: comparison of database and randomised controlled trial findings.
Tannen RL, Weiner MG, Xie D.
BMJ. 2009 Jan 27;338:b81.
PMID: 19174434
Investigation of the temporal association of Guillain-Barre syndrome with influenza vaccine and influenzalike illness using the United Kingdom General Practice Research Database.
Stowe J, Andrews N, Wise L, Miller E.
Am J Epidemiol. 2009 Feb 1;169(3):382-8. Epub 2008 Nov 24.
PMID: 19033158
Is relative mortality of type 2 diabetes mellitus decreasing?.
Gulliford MC, Charlton J.
Am J Epidemiol. 2009 Feb 15;169(4):455-61. Epub 2008 Nov 26.
PMID: 19037005
Rate of suicide in patients taking montelukast.
Jick H, Hagberg KW, Egger P.
Pharmacotherapy. 2009 Feb;29(2):165-6.
PMID: 19170586
Effect of antibiotics for otitis media on mastoiditis in children: a retrospective cohort study using the
United kingdom general practice research database .
Thompson PL, Gilbert RE, Long PF, Saxena S, Sharland M, Wong IC.
Pediatrics. 2009 Feb;123(2):424-30.
PMID: 19171605
Epidemiology of immune thrombocytopenic purpura in the General Practice Research Database.
Marieke Schoonen W, Kucera G, Coalson J, Li L, Rutstein M, Mowat F, Fryzek J, Kaye JA.
Br J Haematol. 2009 Apr;145(2):235-44
PMID: 19245432
An increase in the prevalence of type 1 and 2 diabetes in children and adolescents: results from prescription data from a UK general practice database.
Hsia Y, Neubert AC, Rani F, Viner RM, Hindmarsh PC, Wong IC.
Br J Clin Pharmacol. 2009 Feb;67(2):242-9.
PMID: 19260863
Trends in drug misuse recorded in primary care in the UK from 1998 to 2005.

16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
Frisher M, Martino O, Crome I, Croft P.
J Public Health (Oxf). 2009 Mar;31(1):69-73.
PMID: 18836199
Rise in psychotropic drug prescribing in children and adolescents during 1992-2001: a population-based study in the UK.
Hsia Y, Maclennan K.
Eur J Epidemiol. 2009;24(4):211-6.
PMID: 19266290
How effective are dose-adjusted warfarin and aspirin for the prevention of stroke in patients with chronic atrial fibrillation? An analysis of the UK General Practice Research Database.
Rietbrock S, Plumb JM, Gallagher AM, van Staa TP.
Thromb Haemost. 2009 Mar;101(3):527-34.
PMID: 19277415
Chest pain without established ischaemic heart disease in primary care patients: associated comorbidities and mortality.
Ruigómez A, Massó-González EL, Johansson S, Wallander MA, García-Rodríguez LA.
Br J Gen Pract. 2009 Mar;59(560):e78-86.
PMID: 19275827
Changing trends in antiepileptic drug prescribing in girls of child-bearing potential.
Ackers R, Besag FM, Wade A, Murray ML, Wong IC. C
Arch Dis Child. 2009 Jun;94(6):443-7.
PMID: 19307197
Oral bisphosphonates and risk of atrial fibrillation and flutter in women: a self-controlled case-series safety analysis.
Grosso A, Douglas I, Hingorani A, MacAllister R, Smeeth L.
PLoS ONE. 2009;4(3):e4720.
PMID: 19266096
Attention-deficit hyperactivity disorder: treatment discontinuation in adolescents and young adults.
McCarthy S, Asherson P, Coghill D, Hollis C, Murray M, Potts L, Sayal K, de Soysa R, Taylor E, Williams T,
Wong IC.
Br J Psychiatry. 2009 Mar;194(3):273-7.
PMID: 19252159
Are individuals with an autoimmune disease at higher risk of a second autoimmune disorder?
Somers EC, Thomas SL, Smeeth L, Hall AJ.
Am J Epidemiol. 2009 Mar 15;169(6):749-55. Epub 2009 Feb 18.
PMID: 19224981
Systematic review: the epidemiology of gastro-oesophageal reflux disease in primary care, using the UK
General Practice Research Database.
El-Serag H, Hill C, Jones R.
Aliment Pharmacol Ther. 2009 Mar 1;29(5):470-80. Epub 2008 Nov 25.
PMID: 19035977
Fracture risk in patients receiving acid-suppressant medication alone and in combination with bisphosphonates. de Vries F, Cooper AL, Cockle SM, van Staa TP, Cooper C.
Osteoporos Int. 2009 Dec;20(12):1989-98
PMID:19333676
Risk markers for both chronic fatigue and irritable bowel syndromes: a prospective case-control study in primary care.
Hamilton WT, Gallagher AM, Thomas JM, White PD.

27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
Psychol Med. 2009 Nov;39(11):1913-21
PMID:19366500
Establishing the incidence and prevalence of clinician-diagnosed allergic conditions in children and adolescents using routinely collected data from general practices.
Punekar YS, Sheikh A.
Clin Exp Allergy. 2009 Aug;39(8):1209-16.
PMID: 19400899
A population-based study of perforated diverticular disease incidence and associated mortality.
Humes DJ, Solaymani-Dodaran M, Fleming KM, Simpson J, Spiller RC, West J.
Gastroenterology. 2009 Apr;136(4):1198-205. Epub 2008 Dec 27.
PMID: 19185583
Antidiabetic action of bezafibrate in a large observational database .
Flory JH, Ellenberg S, Szapary PO, Strom BL, Hennessy S.
Diabetes Care. 2009 Apr;32(4):547-51. Epub 2009 Jan 8.
PMID: 19131462
Combined oral contraceptive use and the risk of systemic lupus erythematosus.
Bernier MO, Mikaeloff Y, Hudson M, Suissa S.
Arthritis Rheum. 2009 Apr 15;61(4):476-81.
PMID: 19333988
Antibiotic Prescribing and Outcomes of Lower Respiratory Tract Infection in UK Primary Care.
Winchester CC, Macfarlane T, Thomas M, Price D.
Chest. 2009 May;135(5):1163-72.
PMID: 19420194
Lithium, antipsychotics, and risk of psoriasis.
Brauchli YB, Jick SS, Curtin F, Meier CR.
J Clin Psychopharmacol. 2009 Apr;29(2):134-40.
PMID: 19512974
Mortality associated with attention-deficit hyperactivity disorder (ADHD) drug treatment: a retrospective cohort study of children, adolescents and young adults using the general practice research database.
McCarthy S, Cranswick N, Potts L, Taylor E, Wong IC.
Drug Saf. 2009;32(11):1089-96.
PMID: 19810780
Comorbidities of idiopathic thrombocytopenic purpura: a population-based study.
Feudjo-Tepie MA, Le Roux G, Beach KJ, Bennett D, Robinson NJ.
Adv Hematol.2009;2009: 963506. Epub 2009 Apr 2.
PMID: 19960044
Antihypertensive treatment with ACE inhibitors or beta-blockers and risk of incident atrial fibrillation in a general hypertensive population.
Heckbert SR, Wiggins KL, Glazer NL, Dublin S, Psaty BM, Smith NL, Longstreth WT Jr, Lumley T.
Am J Hypertens. 2009 May;22(5):538-44. Epub 2009 Mar 5.
PMID: 19265792
Long-term use of antidepressants for depressive disorders and the risk of diabetes mellitus.
Andersohn F, Schade R, Suissa S, Garbe E.
Am J Psychiatry. 2009 May;166(5):591-8. Epub 2009 Apr 1.
PMID: 19339356
Rheumatoid arthritis in UK primary care: incidence and prior morbidity.

37. Rodríguez LA, Tolosa LB, Ruigómez A, Johansson S, Wallander MA.
Scand J Rheumatol. 2009 May-Jun;38(3):173-7.
PMID: 19117247
38.
The effect of concurrent pain on the management of patients with depression: an analysis of NHS healthcare resource utilisation using the GPRD database.
Watson L, Baird J, Hösel V, Peveler R.
Int J Clin Pract. 2009 May;63(5):698-706. Epub 2009 Feb 24.
PMID: 19243454
39.
Risk of cataract among idiopathic thrombocytopenic purpura patients in the UK general practice research database.
Feudjo-Tepie MA, Hall SA, Logie J, Robinson NJ.
Pharmacoepidemiol Drug Saf. 2009 May;18(5):380-5.
PMID:19241439
40.
41.
42.
43.
44.
45.
46.
47.
Psoriasis and Risk of Incident Cancer: An Inception Cohort Study with a Nested Case-Control Analysis
Brauchli YB, Jick SS, Miret M, Meier CR.
J Invest Dermatol. 2009 Nov;129(11):2604-12
PMID: 19440219.
The Risk of Stroke in Patients with Psoriasis.
Gelfand JM, Dommasch ED, Shin DB, Azfar RS, Kurd SK, Wang X, Troxel AB.
J Invest Dermatol. 2009 Oct;129(10):2411-8.
PMID: 19458634.
Incidence and lifetime risk of motor neuron disease in the United Kingdom: a population-based study.
Alonso A, Logroscino G, Jick SS, Hernán MA. Eur J
Neurol. 2009 Jun;16(6):745-51.
PMID: 19475756
The epidemiology of Takayasu arteritis in the UK .
Watts R, Al-Taiar A, Mooney J, Scott D, Macgregor A.
Rheumatology (Oxford). 2009 Aug;48(8):1008-11. Epub 2009 Jun 19.
PMID: 19542212
Determining the date of diagnosis--is it a simple matter? The impact of different approaches to dating diagnosis on estimates of delayed care for ovarian cancer in UK primary care.
Tate AR, Martin AG, Murray-Thomas T, Anderson SR, Cassell JA.
BMC Med Res Methodol. 2009 Jun 23;9:42.
PMID: 19549322
Risk of cardiovascular outcomes in users of estradiol/dydrogesterone or other HRT preparations.
Schneider C, Jick SS, Meier CR.
Climacteric. 2009 Oct;12(5):445-53
PMID: 19565370
Use of antidepressants and the risk of Parkinson's disease: a prospective study.
Alonso A, Rodríguez LA, Logroscino G, Hernán MA.
J Neurol Neurosurg Psychiatry. 2009 Jun;80(6):671-4.
PMID: 19448091
Antihypertensive treatment after stroke and all-cause mortality--an analysis of the General
Practitioner Research Database (GPRD).
Toschke AM, Wolfe CD, Heuschmann PU, Rudd AG, Gulliford M.
Cerebrovasc Dis. 2009;28(2):105-11. Epub 2009 Jun 5.
PMID: 19506368
The epidemiology of osteonecrosis: findings from the GPRD and THIN databases in the UK.
Cooper C, Steinbuch M, Stevenson R, Miday R, Watts NB.

48. Osteoporos Int. 2010 Apr;21(4):569-77.
PMID: 19547906.
Assessing the impact of cannabis use on trends in diagnosed schizophrenia in the United Kingdom from
1996 to 2005.
Frisher M, Crome I, Martino O, Croft P
49.
Schizophr Res. 2009 Sep;113(2-3):123-8
PMID: 19560900
50.
51.
Trends in HIV testing and recording of HIV status in the UK primary care setting: a retrospective cohort study 1995-2005.
Evans HE, Mercer CH, Rait G, Hamill M, Delpech V, Hughes G, Brook G, Williams T, Johnson AM, Singh S,
Petersen I, Chadborn T, Cassell JA.
Sex Transm Infect. 2009 Dec;85(7):520-6
PMID: 19564649
Trends in the prescription of anti-diabetic medications in the United Kingdom: a population-based analysis.
Filion KB, Joseph L, Boivin JF, Suissa S, Brophy JM.
Pharmacoepidemiol Drug Saf. 2009 Oct;18(10):973-6
PMID: 19621344
52.
53.
54.
55.
The pattern of risk of myocardial infarction in patients taking asthma medication: a study with the
General Practice Research Database.
J Zhang B, de Vries F, Setakis E, van Staa TP.
Hypertens. 2009 Jul;27(7):1485-92.
PMID: 19491706
The Origin and Spread of a Mumps Epidemic: United Kingdom, 2003-2006.
Jick H, Chamberlin DP, Hagberg KW.
Epidemiology. 2009 Sep;20(5):656-61
PMID: 19593154
Risk of stroke in patients with idiopathic Parkinson disease.
Becker C, Jick SS, Meier CR.
Parkinsonism Relat Disord. 2010 Jan;16(1):31-5.
PMID: 19640771
Incidence and mortality of falls amongst older people in primary care in the United Kingdom
Gribbin J, Hubbard R, Smith C, Gladman J, Lewis S.
QJM. 2009 Jul;102(7):477-83. Epub 2009 Jun 5.
PMID: 19502289.
56.
57.
58.
The risk of unintended pregnancies in users of the contraceptive patch compared to users of oral contraceptives in the UK General Practice Research Database.
Jick SS, Hagberg KW, Kaye JA, Jick H.
Contraception. 2009 Aug;80(2):142-51. 2009 Apr 25.
PMID: 19631789
Alarm symptoms and identification of non-cancer diagnoses in primary care: cohort study.
Jones R, Charlton J, Latinovic R, Gulliford MC.
BMJ. 2009 Aug 13;339:b3094. doi: 10.1136/bmj.b3094.
PMID: 19679615
Utilization characteristics and treatment persistence in patients prescribed low-dose buprenorphine patches in primary care in the United Kingdom: a retrospective cohort study.
Gallagher AM, Leighton-Scott J, van Staa TP.
Clin Ther. 2009 Aug;31(8):1707-15.
PMID: 19808129.

59.
60.
61.
62.
63.
64.
65.
66.
67.
68.
69.
Pay for perfomance and the quality of diabetes management in individuals with and without co-morbid medical conditions.
Millett C, Bottle A, Ng A, Curcin V, Molokhia M, Saxena S, Majeed A.
J R Soc Med. 2009 Sep;102(9):369-77.
PMID: 19734534
Recent trends in lung cancer and its association with COPD: an analysis using the UK GP Research
Database .
Kiri VA, Soriano J, Visick G, Fabbri L.
Prim Care Respir J. 2010 Mar;19(1):57-61
PMID: 19756330.
Selection of medical diagnostic codes for analysis of electronic patient records. Application to stroke in a primary care database.
Gulliford MC, Charlton J, Ashworth M, Rudd AG, Toschke AM; eCRT Research Team.
PLoS One. 2009 Sep 24;4(9):e7168.
PMID: 19777060
The risk of fractures associated with thiazolidinediones: a self-controlled case-series study.
Douglas IJ, Evans SJ, Pocock S, Smeeth L.
PLoS Med. 2009 Sep;6(9):e1000154. Epub 2009 Sep 29.
PMID: 19787025
Prevalence and incidence of Wegener's granulomatosis in the UK general practice research database.
Watts RA, Al-Taiar A, Scott DG, Macgregor AJ. Prevalence and incidence of
Arthritis Rheum. 2009 Oct 15;61(10):1412-6.
PMID: 19790134
Varenicline and suicidal behaviour: a cohort study based on data from the General Practice Research
Database.
Gunnell D, Irvine D, Wise L, Davies C, Martin RM.
BMJ. 2009 Oct 1;339:b3805. doi: 10.1136/bmj.b3805.
PMID: 19797344
Chronic obstructive pulmonary disease and the risk of depression.
Schneider C, Jick SS, Bothner U, Meier CR.
Chest. 2010 Feb;137(2):341-7.
PMID: 19801582
Explaining the rise in antidepressant prescribing: a descriptive study using the general practice research database.
Moore M, Yuen HM, Dunn N, Mullee MA, Maskell J, Kendrick T.
BMJ. 2009 Oct 15;339:b3999. doi: 10.1136/bmj.b3999.
PMID: 19833707
Osteoporosis and venous thromboembolism: a retrospective cohort study in the UK General Practice
Research Database.
Breart G, Cooper C, Meyer O, Speirs C, Deltour N, Reginster JY.
Osteoporos Int. 2010 Jul;21(7):1181-7.
PMID: 19806285.
Cessation of attention deficit hyperactivity disorder drugs in the young (CADDY)--a pharmacoepidemiological and qualitative study .
Wong IC, Asherson P, Bilbow A, Clifford S, Coghill D, DeSoysa R, Hollis C,
McCarthy S, Murray M, Planner C, Potts L, Sayal K, Taylor E. Health Technol Assess. 2009
Oct;13(50):iii-iv, ix-xi, 1-120.
PMID: 19883527.
Chronic obstructive pulmonary disease in UK primary care: incidence and risk factors.
García Rodríguez LA, Wallander MA, Tolosa LB, Johansson S.

70.
71.
72.
73.
74.
75.
76.
77.
78.
79.
COPD. 2009 Oct;6(5):369-79.
PMID: 19863366
Statin use and risk of gallstone disease followed by cholecystectomy.
Bodmer M, Brauchli YB, Krähenbühl S, Jick SS, Meier CR.
JAMA. 2009 Nov 11;302(18):2001-7.
PMID: 19903921
Inhaled tiotropium bromide and risk of stroke
Grosso A, Douglas I, Hingorani AD, MacAllister R, Hubbard R, Smeeth L.
Br J Clin Pharmacol. 2009, Nov;68(5):731-6.
PMID: 19916997
Cancer risk in association with Parkinson disease: A population-based study
Becker C, Brobert GP, Johansson S, Jick SS, Meier CR.
Parkinsonism Relat Disord. 2010 Mar;16(3):186-90
PMID: 19945903
Selective decrease in consultations and antibiotic prescribing for acute respiratory tract infections in UK primary care up to 2006.
Gulliford M, Latinovic R, Charlton J, Little P, van Staa T, Ashworth M.
J Public Health (Oxf). 2009 Dec;31(4):512-20. Epub 2009 Sep 4.
PMID: 19734168
Prevalence of acute repetitive seizures (ARS) in the United Kingdom.
Martinez C, Sullivan T, Hauser WA.
Epilepsy Res. 2009 Dec;87(2-3):137-43. Epub 2009 Sep
PMID: 19748226
Establishing the sequential progression of multiple allergic diagnoses in a UK birth cohort using the
General Practice Research Database.
Punekar YS, Sheikh A.
Clin Exp Allergy. 2009 Dec;39(12):1889-95. Epub 2009 Oct 7.
PMID: 19817751
Primary care consultations and costs among HIV-positive individuals in UK primary care 1995-2005: a cohort study.
Evans HE, Tsourapas A, Mercer CH, Rait G, Bryan S, Hamill M, Delpech V, Hughes G, Brook G, Williams T,
Johnson AM, Singh S, Petersen I, Chadborn T, Cassell JA.
Sex Transm Infect. 2009 Dec; 85(7):543-9. Epub 2009 Oct 22.
PMID: 19854699
Risk of cardiovascular disease and all cause mortality among patients with type 2 diabetes prescribed oral antidiabetes drugs: retrospective cohort study using UK general practice research database.
Tzoulaki I, Molokhia M, Curcin V, Little MP, Millett CJ, Ng A, Hughes RI, Khunti K, Wilkins MR, Majeed A,
Elliott P.
BMJ. 2009 Dec 3;339:b4731
PMID: 19959591
What happens to new-onset headache in children that present to primary care? A case-cohort study using electronic primary care records.
Kernick D, Stapley S, Campbell J, Hamilton W.
Cephalalgia. 2009 Dec;29(12):1311-6.
PMID: 19911465.
Risk of ischemic stroke in patients with Crohn's disease: A population-based nested case-control study .
Andersohn F, Waring M, Garbe E.
Inflamm Bowel Dis. 2010 Aug;16(8):1387-92.
PMID: 20014016.

80.
81.
82.
83.
84.
85.
Patients with severe psoriasis are at increased risk of cardiovascular mortality: cohort study using the
General Practice Research Database.
Mehta NN, Azfar RS, Shin DB, Neimann AL, Troxel AB, Gelfand JM.
Eur Heart J. 2010 Apr;31(8):1000-6
PMID: 20037179
Risk of gynecological cancers in users of estradiol/dydrogesterone or other HRT preparations.
Schneider C, Jick SS, Meier CR. Climacteric.
2009 Dec;12(6):514-24.
PMID: 19905903
A comparison of cost effectiveness using data from randomized trials or actual clinical practice: selective cox-2 inhibitors as an example. van Staa TP, Leufkens HG, Zhang B, Smeeth L.
PLoS Med. 2009 Dec;6(12):e1000194. Epub 2009 Dec 8.
PMID: 19997499
Thiazolidinediones and the risk of incident strokes in patients with type 2 diabetes: a nested case-control study.
Azoulay L, Schneider-Lindner V, Dell'aniello S, Filion KB, Suissa S.
Pharmacoepidemiol Drug Saf. 2010 Apr;19(4):343-50.
PMID: 19998318
Hip Fracture Risk in Patients with a Diagnosis of Pernicious Anemia.
Merriman NA, Putt ME, Metz DC, Yang YX.
Gastroenterology. 2010 Apr;138(4):1330-7.
PMID: 20026065
Cost effectiveness of travoprost versus a fixed combination of latanoprost/timolol in patients with ocular hypertension or glaucoma: analysis based on the UK general practitioner research database.
De Natale R, Lafuma A, Berdeaux G.
Clin Drug Investig. 2009;29(2):111-20.
PMID: 19133706
1.
2.
3.
4.
Migraine incidence, comorbidity and health resource utilization in the UK.
Becker C, Brobert GP, Almqvist PM, Johansson S, Jick SS, Meier CR.
Cephalalgia. 2008 Jan;28(1):57-64. Epub 2007 Nov 6.
PMID: 17986274
The Risk of Newly Diagnosed Asthma in Migraineurs With or Without Previous Triptan Prescriptions
Becker C, Brobert GP, Almqvist PM, Johansson S, Jick SS, Meier CR.
Headache. 2008 Apr;48(4):606-10
PMID: 18194300
Association between use of thiazolidinediones or other oral antidiabetics and psoriasis: a population based case-control study.
Brauchli YB, Jick SS, Curtin F, Meier CR.
J Am Acad Dermatol. 2008 Mar;58(3):421-9
PMID: 18194825
No association between routinely recorded infections in early life and subsequent risk of childhood-onset
Type 1 diabetes: a matched case-control study using the UK General Practice Research Database.
Cardwell CR, Carson DJ, Patterson CC.
Diabet Med. 2008 Mar;25(3):261-7.

9.
7.
5.
6.
8.
10.
11.
12.
13.
14.
PMID: 18201209
Adverse events associated with prolonged antibiotic use.
Meropol SB, Chan KA, Chen Z, Finkelstein JA, Hennessy S, Lautenbach E, Platt R, Schech SD, Shatin D,
Metlay JP.
Pharmacoepidemiol Drug Saf. 2008 May;17(5):523-32.
PMID: 18215001
Data Resources for Investigating Drug Exposure during Pregnancy and Associated Outcomes: The
General Practice Research Database (GPRD) as an Alternative to Pregnancy Registries.
Charlton RA, Cunnington MC, de Vries CS, Weil JG.
Drug Saf. 2008;31(1):39-51.
PMID: 18095745
Is obesity associated with gastropharyngeal reflux disease?.
Choi CW, Kim GH, Song CS, Wang SG, Lee BJ, I H, Kang DH, Song GA.
World J Gastroenterol. 2008 Jan 14;14(2):265-71.
PMID: 18186566
Mortality after infection with methicillin resistant Staphylococcus aureus (MRSA) diagnosed in the community.
Delaney JA, Schneider-Lindner V, Brassard P, Suissa S.
BMC Med. 2008 Jan 31;6:2
PMID: 18234115
Antidepressant drug use and risk of venous thromboembolism.
Jick SS, Li L.
Pharmacotherapy. 2008 Feb;28(2):144-50.
PMID: 18225961
Nonsteroidal anti-inflammatory drug use and the risk of severe skin and soft tissue complications in patients with varicella or zoster disease.
Mikaeloff Y, Kezouh A, Suissa S.
Br J Clin Pharmacol. 2008 Feb;65(2):203-9.
PMID: 18251759
Replicated studies of two randomized trials of angiotensin- converting enzyme inhibitors: further empiric validation of the 'prior event rate ratio' to adjust for unmeasured confounding by indication.
Tannen RL, Weiner MG, Xie D.
Pharmacoepidemiol Drug Saf. 2008 Mar 10;17(7):671-685.
PMID: 18327852
Replication of the Scandinavian Simvastatin Survival Study using a primary care medical record database prompted exploration of a new method to address unmeasured confounding.
Weiner MG, Xie D, Tannen RL
Pharmacoepidemiol Drug Saf. 2008 Mar 10;17(7):661-670.
PMID: 18327857
Prevalence and predictors of lipid abnormalities in patients treated with statins in the UK general practice.
Phatak H, Wentworth C, Sazonov V, Burke T.
Atherosclerosis. 2009 Jan;202(1):225-33.
PMID: 18457840
Infections presenting for clinical care in early life and later risk of hay fever in two uk birth cohorts .
Bremner SA, Carey IM, DeWilde S, Richards N, Maier WC, Hilton SR, Strachan DP, Cook DG
Allergy. 2008 Mar;63(3):274-83.
PMID: 18269673

15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
Individualizing the risks and benefits of postmenopausal hormone therapy.
van Staa TP, Cooper C, Barlow D, Leufkens HG.
Menopause. 2008 Mar-Apr;15(2):374-81.
PMID: 17882009
What is the harm-benefit ratio of Cox-2 inhibitors?
van Staa TP, Smeeth L, Persson I, Parkinson J, Leufkens HG.
Int J Epidemiol. 2008 Apr;37(2):405-13. Epub 2008 Feb 8.
PMID: 18263647
Onset of acute myocardial infarction after use of non-steroidal anti-inflammatory drugs.
Hammad TA, Graham DJ, Staffa JA, Kornegay CJ, Dal Pan GJ
Pharmacoepidemiol Drug Saf. 2008 Apr;17(4):315-21.
PMID: 18302311
Chronic statin therapy and the risk of colorectal cancer.
Yang YX, Hennessy S, Propert K, Hwang WT, Sarkar M, Lewis JD.
Pharmacoepidemiol Drug Saf. 2008 Sep;17(9):869-76.
PMID: 18412290
The safety of rosuvastatin in comparison with other statins in over 100 000
García-Rodríguez LA, Gonzalez EM, Wallander MA, Johansson S.
Pharmacoepidemiol Drug Saf. 2008 Oct;17(10):943-52
PMID: 18425988
Use of thiazolidinediones and fracture risk.
16: Meier C, Kraenzlin ME, Bodmer M, Jick SS, Jick H, Meier CR.
Arch Intern Med. 2008 Apr 28;168(8):820-5.
PMID: 18443256
Evaluating drug toxicity signals: is a hierarchical classification of evidence useful or a hindrance? van Staa TP, Smeeth L, Persson I, Parkinson J, Leufkens HG.
Pharmacoepidemiol Drug Saf. 2008 May;17(5):475-84.
PMID: 18322905
Validation of neural tube defects in the full featured--general practice research database .
Devine S, West SL, Andrews E, Tennis P, Eaton S, Thorp J, Olshan A.
Pharmacoepidemiol Drug Saf. 2008 May;17(5):434-44.
PMID: 18344214
Use of statins and the risk of Parkinson's disease: a retrospective case-control study in the UK.
Becker C, Jick SS, Meier CR.
Drug Saf. 2008;31(5):399-407.
PMID: 18422380
Epidemiologic features of antipsychotic prescribing to children and adolescents in primary care in the
United Kingdom .
Rani F, Murray ML, Byrne PJ, Wong IC
Pediatrics. 2008 May;121(5):1002-9.
PMID: 18450906
Epidemiology and cost of herpes zoster and post-herpetic neuralgia in the United Kingdom.
Gauthier A, Breuer J, Carrington D, Martin M, Rémy V.
Epidemiol Infect. 2009 Jan;137(1):38-47
PMID: 18466661
Lipid Testing among Patients Beginning Statin Therapy in General Practice in the United Kingdom.
Phatak H, Wentworth C, Burke TA
Value Health. 2008 Sep-Oct;11(5):933-8.
PMID: 18489501

27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
Fracture Outcomes Related to Persistence and Compliance with Oral Bisphosphonates.
Gallagher A, Rietbrock S, Olson M, van Staa T .
J Bone Miner Res. 2008 Oct;23(10):1569-75
PMID: 18505366
Low identification of alcohol use disorders in general practice in England.
Cheeta S, Drummond C, Oyefeso A, Phillips T, Deluca P, Perryman K, Coulton S.
Addiction. 2008 May;103(5):766-73.
PMID: 18412755
Explaining the decline in early mortality in men and women with type 2 diabetes. Population-based cohort study.
Charlton J, Latinovic R, Gulliford MC.
Diabetes Care. 2008 Sep;31(9):1761-6.
PMID: 18509209
Costs and persistence of carbonic anhydrase inhibitor versus alpha-2 agonists, associated with betablockers, in glaucoma and ocular hypertension: an analysis of the UK-GPRD database.
Lafuma A, Berdeaux G.
Curr Med Res Opin. 2008 May;24(5):1519-27. Epub 2008 Apr 14.
PMID: 18413015
Validating the effects of drug treatment on blood pressure in the General Practice Research Database.
Delaney JA, Moodie EE, Suissa S.
Pharmacoepidemiol Drug Saf. 2008 Jun;17(6):535-45.
PMID: 18265414
Comparison of tiotropium bromide and combined ipratropium/salbutamol for the treatment of COPD: a
UK General Practice Research Database 12-month follow-up study.
Griffin J, Lee S, Caiado M, Kesten S, Price D.
Prim Care Respir J. 2008 Jun;17(2):104-10.
PMID: 18385913
Association between beta-blockers, other antihypertensive drugs and psoriasis: population-based casecontrol study.
Brauchli YB, Jick SS, Curtin F, Meier CR.
Br J Dermatol. 2008 Jun;158(6):1299-307. Epub 2008 Apr 10.
PMID: 18410416
Incidence and mortality of primary sclerosing cholangitis in the UK: a population-based cohort study.
Card TR, Solaymani-Dodaran M, West J.
J Hepatol. 2008 Jun;48(6):939-44. Epub 2008 Mar 31.
PMID: 18433916
Immunosuppressant medications and mortality in inflammatory bowel disease.
Lewis JD, Gelfand JM, Troxel AB, Forde KA, Newcomb C, Kim H, Margolis DJ,
Strom BL
Am J Gastroenterol. 2008 Jun;103(6):1428-35; quiz 1436. Epub 2008 May 20.
PMID: 18494836
Diabetes mellitus in patients with idiopathic Parkinson's disease.
Becker C, Brobert GP, Johansson S, Jick SS, Meier CR.
Diabetes Care. 2008 Sep;31(9):1808-12.
PMID: 18559656
Protective effect of antibiotics against serious complications of common respiratory tract infections: retrospective cohort study with the UK General Practice Research Database.
Petersen I, Johnson AM, Islam A, Duckworth G, Livermore DM, Hayward AC.

38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
Clin Otolaryngol. 2008 Jun;33(3):252.
PMID: 18559032
Initiation and persistence of warfarin or aspirin in patients with chronic atrial fibrillation in general practice: do the appropriate patients receive stroke prophylaxis
Gallagher A, Rietbrock S, Plumb J, van Staa TP
J Thromb Haemost. 2008 Sep;6(9):1500-6. Epub 2008 Jun 28.
PMID: 18573187
Risk of myocardial infarction in men and women with type 2 diabetes in the UK: a cohort study using the
General Practice Research Database.
Mulnier HE, Seaman HE, Raleigh VS, Soedamah-Muthu SS, Colhoun HM, Lawrenson
RA, de Vries CS.
Diabetologia. 2008 Sep;51(9):1639-45.
PMID: 18581091
Discontinuation of statin therapy following an acute myocardial infarction: a population-based study.
Daskalopoulou SS, Delaney JA, Filion KB,Brophy JM, Mayo NE, Suissa S.
Eur Heart J. 2008 Sep;29(17):2083-91
PMID: 18664465
Gastro-intestinal haemorrhage risks of selective serotonin receptor antagonist therapy: a new look.
Opatrny L, Delaney JA, Suissa S.
Br J Clin Pharmacol. 2008 Jul;66(1):76-81. Epub 2008 May 6.
PMID: 18460039
Chronic atrial fibrillation: Incidence, prevalence, and prediction of stroke using the Congestive heart failure, Hypertension, Age >75, Diabetes mellitus, and prior Stroke or transient ischemic attack
(CHADS2) risk stratification scheme.
Rietbrock S, Heeley E, Plumb J, van Staa T.
Am Heart J. 2008 Jul;156(1):57-64.
PMID: 18585497
Risk of upper gastrointestinal tract bleeding associated with selective serotonin reuptake inhibitors and venlafaxine therapy: interaction with nonsteroidal anti-inflammatory drugs and effect of acid-suppressing agents. de Abajo FJ, García-Rodríguez LA
Arch Gen Psychiatry. 2008 Jul;65(7):795-803.
PMID: 18606952
Obesity and the use of insulin: a study of patients with type 2 diabetes in the UK.
Yurgin N, Secnik K, Lage MJ
J Diabetes Complications. 2008 Jul-Aug;22(4):235-40. Epub 2008 Apr 16.
PMID: 18413211
Risk of Cardiovascular and Cerebrovascular Events in Primary Billiary Cirrhosis:
A population-Based Cohort Study
Solaymani-Dodaran M, Aithal GP, Card T, West J.
Am J Gastroenterol. 2008 Aug 27
PMID: 18759822
Proton pump inhibitor use and risk of hip fractures in patients without major risk factors.
Kaye JA, Jick H.
Pharmacotherapy. 2008 Aug;28(8):951-9.
PMID: 18657011
Changes in the characteristics of patients prescribes selective cyclooxygenase 2 inhibitors after the 2004 withdrawal of rofecoxib
Setakis E, Leufkens HG, van Staa TP
Arthritis Rheum. 2008 Aug 15;59(8): 1105-11

48.
49.
50.
51.
52.
53.
54.
55.
56.
57.
58.
PMID: 18668614
Relationship Between Gastroesophageal Reflux Disease and COPD in UK Primary Care.
Garcia Rodriuez LA, Martin-Merino E, Johansson S, Wallander MA,
Chest. 2008 Dec;134(6):1223-30
PMID: 18689591
Irritable Bowel Syndrome and Gastroesophagael Reflux Disease in Primary Care. Is there a link?
Ruigomez A, Wallander MA, Johansson S, Rodriguez LA.
Dig Dis Sci. 2009 May;54(5):1079-86
PMID: 18720002
Prescribing trends in asthma: a longitudinal observational study.
Turner SW, Thomas M, von Ziegenweidt J, Price D.
Arch Dis Child. 2009 Jan;94(1):16-22
PMID: 18701558
Risk of myocardial infarction and overall mortality in survivors of venous thrombolism
Huerta C, Johansson S, Wallander MA, Rodriguez LA
Thrombo J 2008 Aug 18; 6:10
PMID: 18706117
Exposure to antipsychotics and risk of stroke: self controlled case series study .
Douglas IJ, Smeeth L.
BMJ. 2008 Aug 28;337:al1227.doi: 10.1136/bmj.a1227
PMID: 18755769
Sex- and age-specific incidence of fractures in mental illness: a historical, population-based cohort study.
Abel KM, Heatlie HF, Howard LM, Webb RT.
J Clin Psychiatry. 2008 Sep;69(9):1398-403.
PMID: 19193340.
Has UK guidance affected general practitioner antibiotic prescribing for otitis media in children?
Thompson PL, Gilbert RE, Long PF, Saxena S, Sharland M, Wong IC.
J Public Health (Oxf). 2008 Dec;30(4):479-86
PMID 18765405
Psoriasis and the risk of incident diabetes mellitus: a population-based study
Brauchli YB, Jick SS, Meier CR.
Br J Dermatol. 2008 Dec;159(6):1331-7
PMID: 18782318
Age-related Macular Degeneration and Complement Activation-Related Disease A. Population-Based
Case-Control Study
Nitsch D, Douglas I, Smeeth L, Fletcher A
Ophthalmology. 2008 Nov;115(11):1904-10.
PMID: 18801575
How accurate are diagnoses for rheumatoid arthritis and juvenile idiopathic arthritis in the general practice research database?
Thomas SL, Edwards CJ, Smeeth L, Cooper C, Hall AJ.
Arthritis Rheum.2008 Sep 15;59 (9): 1314-21
PMID: 18759262
Endometriosis and its coexistence with irritable bowel syndrome and pelvic inflammatory disease: findings from a national case-control study-Part 2.
Seaman HE, Ballard KD, Wright JT, de Vries CS.
BJOG 2008 Oct; 115(11): 1392-6. Epub 2008 Aug 19
PMID: 18715239

59.
60.
61.
62.
63.
64.
65.
66.
67.
68.
Psychiatric and cardiovascular comorbidities in patients with diabetes mellitus starting antiobesity drugs.
Willemen MJ, Mantel-Teeuwisse AK, Straus SM, Leufkens HG, Egberts AC.
Obesity (Silver Spring) 2008 Oct; 16(10):2331-5 Epub 2008 Jul 24
PMID: 18719629
Traditional versus marginal structural models to estimate the effectiveness of beta-blocker use on mortality after myocardial infarction .
Delaney JA, Daskalopoulou MD Phd SS, Suissa S
Pharmacoepidemiol Drug Saf. 2009 Jan;18(1):1-6
PMID: 18949804
Panic disorder and risk of new onset coronary heart disease, acute myocardial infarction, and cardiac mortality: cohort study using the general practice research database.
Walters K, Rait G, Petersen I, Williams R, Nazareth
Eur Heart J. 2008 Dec;29(24):2981-8.
PMID: 18948354
Trends in drug misuse recorded in primary care in the UK from 1998 to 2005.
Frisher M, Martino O, Crome I, Croft P.
Curr Opin Cell Biol. 1991 Apr;3(2):261-8.
PMID: 1883619
The potential effects on fracture outcomes of improvements in persistence and compliance with bisphosphonates
Reitbrock S, Olson M, Van Staa TP
QJM. 2009 Jan;102(1):35-42.
PMID: 18842684
Does the varied use of NSAIDs explain the differences in the risk of myocardial infarction?
. van Staa TP, Rietbrock S, Setakis E, Leufkens HG.
J Intern Med. 2008 Nov;264(5):481-92. Epub 2008 Jun 25.
PMID: 18624902.
High do es inhaled corticosteroids versus add-on long-acting beta-agonists in asthma: An observational study.
Thomas M, von Ziegenweidt J, Lee AJ, Price D.
J Allergy Clin Immunol. 2009 Jan;123(1):116-121.e10.
PMID 18986690
Hormone replacement therapy use and the risk of stroke
Renoux C, Dell’aniello S, Garbe E, Suissa S.
Maturitas. 2008 Dec 20;61(4):305-9
PMID: 18996656
Infections in early life and childhood leukaemia risk: a UK case-control study of general practitioner records
Cardwell cR, McKinney PA, Patterson CC. Murray LJ.
Br J Cancer. 2008 Nov 4; 99 (9) : 1529-33. Epub 2008 Sep 30.
PMID 18827817
Determing the predictive value of Read/OXMIS codes to identify incident acute myocardial infarction in the General Practice Database .
Hammad TA, McAdams MA, Feight A, Iyasu S, Dal Pan GJ.
Pharmacoepidemiol Drug Saf. 2008 Dec;17(12):1197-201
PMID: 18985705
Malignancies in the rheumatoid arthritis abatacept clinical development program: An epidemiological

69.
70.
71.
72. assessment.
Simon TA, Smitten AL, Franklin J, Askling J, Lacaille D, Wolfe F, Hochberg MC, Qi K, Suissa S.
Ann Rheum Dis. 2009 Dec;68(12):1819-26
PMID: 19054822
Use of hormonal contraceptive methods by women with diabetes.
Shawe J, Mulnier H, Nicholls P, Lawrenson R.
Prim Care Diabetes. 2008 Dec;2(4):195-9. Epub 2008 Nov 18.
PMID: 19019754
Costs and persistence of brimonidine versus brinzolamide in everyday glaucoma care: an analysis conducted on the UK General Practitioner Research Database.
Lafuma A, Laurendeau C, Berdeaux G
J Med Econ. 2008;11(3):485-97.
PMID: 19450100
Costs and persistence of alpha-2 adrenergic agonists versus carbonic anhydrase inhibitors, both associated with prostaglandin analogues, for glaucoma as recorded by The United Kingdom General Practitioner
Research Database.
Denis P, Lafuma A, Berdeaux G.
Clin Ophthalmol. 2008 Jun;2(2):321-9.
PMID: 19668723

7.
9.
1.
2.
3.
4.
5.
6.
8.
10.
Use of antibiotics for sore throat and incidence of quinsy.
Dunn N, Lane D, Everitt H, Little P.
Br J Gen Pract. 2007 Jan;57(534):45-9.
PMID: 17244424
Incidence of skeletal complications during treatment of childhood acute lymphoblastic leukemia: comparison of fracture risk with the General Practice Research Database.
Hogler W, Wehl G, van Staa T, Meister B, Klein-Franke A, Kropshofer G.
Pediatr Blood Cancer. 2007 Jan;48(1):21-7.
PMID: 16317756
Fracture risk with intermittent high-dose oral glucocorticoid therapy.
De Vries F, Bracke M, Leufkens HG, Lammers JW, Cooper C, Van Staa TP.
Arthritis Rheum. 2007 Jan;56(1):208-14.
PMID: 17195223
Dopamine agonists and the risk of cardiac-valve regurgitation .
Schade R, Andersohn F, Suissa S, Haverkamp W, Garbe E.
N Engl J Med. 2007 Jan 4;356(1):29-38.
PMID: 17202453
Measuring disease prevalence: a comparison of musculoskeletal disease using four general practice consultation databases.
Jordan K, Clarke AM, Symmons DP, Fleming D, Porcheret M, Kadam UT, Croft P.
Br J Gen Pract. 2007 Jan;57(534):7-14.
PMID: 17244418
Angiotensin-converting enzyme inhibitor use and protection against pneumonia in patients with diabetes. van de Garde EM, Souverein PC, Hak E, Deneer VH, van den Bosch JM, Leufkens HG.
J Hypertens. 2007 Jan;25(1):235-9.
PMID: 17143196
Systematic lupus erythematosus prevalence in the UK: methodological issues when using the General
Practice Research Database to estimate frequenc y of chronic relapsing-remitting disease.
Nightingale AL, Farmer RD, de Vries CS. Related Articles, Links
Pharmacoepidemiol Drug Saf. 2007 Feb;16(2):144-51.
PMID: 16700093
Use of beta-Blockers and the Risk of Hip/Femur Fracture in the United Kingdom and The Netherlands . de Vries F, Souverein PC, Cooper C, Leufkens HG, van Staa TP.
Calcif Tissue Int. 2007 Feb;80 (2):69-75. Epub 2007 Feb 2.
PMID: 17308987
Risk of suicide during treatment with venlafaxine, citalopram, fluoxetine, and dothiepin: retrospective cohort study.
Rubino A, Roskell N, Tennis P, Mines D, Weich S, Andrews E.
BMJ. 2007 Feb 3;334 (7587):242. Epub 2006 Dec 12.
PMID: 17164297
Risk of hip fracture in patients with a history of schizophrenia.
Howard L, Kirkwood G, Leese M.
Br J Psychiatry. 2007 Feb;190:129-34.
PMID: 17267929

11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
Relative risk of cardiovascular and cancer mortality in people with severe mental illness from the United Kingdom's General Practice Research Database.
Osborn DP, Levy G, Nazareth I, Petersen I, Islam A, King MB.
Arch Gen Psychiatry. 2007 Feb;64(2):242-9. Erratum in: Arch Gen Psychiatry. 2007 Jun;64(6):736.
PMID: 17283292
Risk of colorectal cancer in women with a prior diagnosis of gynaecologic malignancy.
Srinivasan R, Yang YX, Rubin SC, Morgan MA, Lewis JD.
J Clin Gastroenterol. 2007 Mar;41(3):291-6.
PMID: 17426469
Statins and the risk of pneumonia: a population-based, nested case-control study.
Schlienger RG, Fedson DS, Jick SS, Jick H, Meier CR.
Pharmacotherapy. 2007 Mar;27(3):325-32.
PMID: 17316144
Initial monotherapy with either metformin or sulphonylureas often fails to achieve or maintain current glycaemic goals in patients with Type 2 diabetes in UK primary care.
Cook MN, Girman CJ, Stein PP, Alexander CM.
Diabet Med. 2007 Apr;24(4):350-8.
PMID: 17335466
Vaccinations, infections and antibacterials in the first grass pollen season of life and risk of later hayfever
Bremner SA, Carey IM, DeWilde S, Richards N, Maier WC, Hilton SR, Strachan DP, Cook DG.
Clin Exp Allergy. 2007 Apr;37(4):512-7.
PMID: 17430347
Incidence of systemic lupus erythematosus in the United Kingdom
Somers EC, Thomas SL, Smeeth L, Schoonen WM, Hall AJ., 1990-1999.
Arthritis Rheum. 2007 Apr 30;57(4):612-618
PMID: 17471530
Evaluation of the general practice research database congenital heart defects prevalence: Comparison to
United Kingdom national systems.
Wurst KE, Ephross SA, Loehr J, Clark DW, Guess HA.
Birth Defects Res A Clin Mol Teratol. 2007 Apr;79(4): 309-16.
PMID: 17286297
Diclofenac and acute myocardial infarction in patients with no major risk factors.
Jick SS, Kaye JA, Jick H.
Br J Clin Pharmacol. 2007 Nov;64(5):662-7.
PMID: 17509036
Risk factors and short-term mortality of venous thromboembolism diagnosed in the primary care setting in the United Kingdom.
Huerta C, Johansson S, Wallander MA, Garcia Rodriguez LA.
Arch Intern Med. 2007 May 14;167(9):935-43.
PMID: 17502535
Alarm symptoms in early diagnosis of cancer in primary care: cohort study using General Practice
Research Database.
Jones R, Latinovic R, Charlton J, Gulliford MC.
BMJ. 2007 May 19;334(7602):1040 .
PMID: 17493982
Individual fracture risk and the cost-effectiveness of bisphosphonates in patients using oral glucocorticoids. van Staa TP, Geusens P, Zhang B, Leufkens HG, Boonen A, Cooper C.
Rheumatology (Oxford). 2007 Mar;46(3):460-6. Epub 2006 Aug 9.

22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
PMID: 16899499
Hormone therapy and coronary heart disease in young women.
Weiner MG, Barnhart K, Xie D, Tannen RL.
Menopause. 2008 Jan-Feb;15(1):86-93.
PMID: 17502840
Lithium use and the risk of fractures.
Wilting I, de Vries F, Thio BM, Cooper C, Heerdink ER, Leufkens HG, Nolen WA, Egberts AC, van Staa TP
Bone. 2007 May;40(5):1252-8
PMID: 17258948
Preferential prescribing of tibolone and combined estrogen plus progestogen therapy in postmenopausal women.
Velthuis-Te Wierik EJ, Hendricks PT, Martinez C.
Menopause. 2007 May-Jun;14(3 Pt 1):518-27.
PMID: 17224856
Prioritizing children's medicines for research: a pharmaco-epidemiological study of antiepileptic drugs.
Ackers R, Murray ML, Besag FM, Wong IC.
Br J Clin Pharmacol. 2007 Jun;63(6):689-97. Epub 2007 Jan 25.
PMID: 17257162
Assessing the burden of influenza and other respiratory infections in England and Wales
Pitman RJ, Melegaro A, Gelb D, Siddiqui MR, Gay NJ, Edmunds WJ.
J Infect. 2007 Jun;54(6):530-8.
PMID: 17097147
Venous thromboembolism and cyproterone acetate in men with prostate cancer: a study using the General Practice Research Database.
Seaman HE, Langley SE, Farmer RD, de Vries CS.
BJU Int. 2007 Jun;99(6):1398-403 .
PMID: 17537215
A case-control study of drug risk factors for age-related macular degeneration.
Douglas IJ, Cook C, Chakravarthy U, Hubbard R, Fletcher AE, Smeeth L.
Ophthalmology. 2007 Jun;114(6):1164-9.
PMID: 17544775
Estrogen affects post-menopausal women differently than estrogen plus progestin replacement therapy.
Tannen RL, Weiner MG, Xie D, Barnhart K.
Hum Reprod. 2007 Jun;22(6):1769-77 .
PMID: 17347166
The effect of antihypertensive drugs and drug combinations on the incidence of new-onset type-2 diabetes mellitus.
Burke TA, Sturkenboom MC, Ohman-Strickland PA, Wentworth CE, Rhoads GG.
Pharmacoepidemiol Drug Saf. 2007 Sep;16(9):979-87
PMID: 17605137
A simulation using data from a primary care practice database closely replicated the women's health initiative trial.
Tannen RL, Weiner MG, Xie D, Barnhart K.
J Clin Epidemiol. 2007 Jul;60(7):686-95. Epub 2006 Dec 27.
PMID: 17573984
The utility of the general practice research database to examine selected congenital heart defects: a validation study.

32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
Wurst KE, Ephross SA, Loehr J, Clark DW, Guess HA.
Pharmacoepidemiol Drug Saf. 2007 Aug; 16(8):867-77.
PMID: 17563909
Drug drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding.
Delaney JA, Opatrny L, Brophy JM, Suissa S.
CMAJ 2007 Aug 14; 177(4):347-51.
PMID: 17698822
The use of antibacterials in children: a report of the Specialist Advisory Committee on Antimicrobial
Resistance (SACAR) Paediatric Subgroup.
Sharland M; SACAR Paediatric Subgroup.
J Antimicrob Chemother. 2007 Aug; 60 Suppl 1:i15-26.
PMID: 17656377
Antibacterial prescribing in primary care.
Petersen I, Hayward AC; SACAR Surveillance Subgroup.
J Antimicrob Chemother. 2007 Aug; 60 Suppl 1:i43-47.
PMID: 17656380
Antibacterial prescribing in primary care.
Petersen I, Hayward AC; SACAR Surveillance Subgroup.
J Antimicrob Chemother. 2007 Aug; 60 Suppl 1:i43-47.
PMID: 17656380
Risk for active tuberculosis in inflammatory bowel disease patients.
Aberra FN, Stettler N, Brensinger C, Lichtenstein GR, Lewis JD.
Clin Gastroenterol Hepatol. 2007 Sep;5(9):1070-5. Epub 2007 Jul 12.
PMID: 17627901
Chronic proton pump inhibitor therapy and the risk of colorectal cancer.
Yang YX, Hennessy S, Propert K, Hwang WT, Sedarat A, Lewis JD.
Gastroenterology. 2007 Sep;133(3):748-54. Epub 2007 Jun 20.
PMID: 17678926
Observed association between antidepressant use and pneumonia risk was confounded by comorbidity measures.
Hennessy S, Bilker WB, Leonard CE, Chittams J, Palumbo CM, Karlawish JH, Yang YX, Lautenbach E, Baine
WB, Metlay JP.
J Clin Epidemiol. 2007 Sep;60(9):911-8. Epub 2007 May 10.
PMID: 17689807
Clinical features of primary brain tumours: a case-control study using electronic primary care records.
Hamilton W, Kernick D.
Br J Gen Pract. 2007 Sep;57(542):695-9.
PMID: 17761056
Association between the use of beta-adrenergic receptor agents and the development of venous leg ulcers.
Margolis DJ, Hoffstad O, Isseroff RR.
Arch Dermatol. 2007 Oct;143(10):1275-80.
PMID: 17938341
Unspecified abdominal pain in primary care: the role of gastrointestinal morbidity.
Wallander MA, Johansson S, Ruigómez A, García Rodríguez LA.
Int J Clin Pract. 2007 Oct;61(10):1663-70. Epub 2007 Aug 6.
PMID: 17681003
Influence of ursodeoxycholic acid on the mortality and malignancy associated with primary biliary cirrhosis: a population-based cohort study.
Jackson H, Solaymani-Dodaran M, Card TR, Aithal GP, Logan R, West J.

44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
Hepatology. 2007 Oct;46(4):1131-7.
PMID: 17685473
The importance of the disease process and disease-modifying antirheumatic drug treatment in the development of septic arthritis in patients with rheumatoid arthritis.
Edwards CJ, Cooper C, Fisher D, Field M, van Staa TP, Arden NK.
Arthritis Rheum. 2007 Oct 15;57(7):1151-7.
PMID: 17907232
Gout and risk of Parkinson disease: a prospective study.
Alonso A, Rodríguez LA, Logroscino G, Hernán MA.
Neurology. 2007 Oct 23;69(17):1696-700.
PMID: 17954784
Drug treatment discontinuation and achievement of target blood pressure and cholesterol in United
Kingdom primary care.
MacDonald TM, Morant SV, Mozaffari E.
Curr Med Res Opin. 2007 Nov;23(11):2765-74.
PMID: 17919356
Protective effect of antibiotics against serious complications of common respiratory tract infections: retrospective cohort study with the UK General Practice Research Database.
Petersen I, Johnson AM, Islam A, Duckworth G, Livermore DM, Hayward AC.
BMJ. 2007 Nov 10;335(7627):982. Epub 2007 Oct 18.
PMID: 17947744
Migraine and the risk of stroke, TIA, or death in the UK (CME).
Becker C, Brobert GP, Almqvist PM, Johansson S, Jick SS, Meier CR.
Headache. 2007 Nov-Dec;47(10):1374-84.
PMID: 18052947
Incidence of multiple sclerosis in the United Kingdom : Findings from a population-based cohort.
Alonso A, Jick SS, Olek MJ, Hernán MA.
J Neurol. 2007 Dec;254(12):1736-41. Epub 2007 Oct 1.
PMID: 17896096
The risk of herpes zoster in patients with rheumatoid arthritis in the United States and the United
Kingdom.
Smitten AL, Choi HK, Hochberg MC, Suissa S, Simon TA, Testa MA, Chan KA.
Arthritis Rheum. 2007 Dec 15;57(8):1431-8.
PMID: 18050184
Risk of cerebrovascular accident after a first diagnosis of atrial fibrillation.
Ruigómez A, García Rodríguez LA, Johansson S, Wallander MA, Edvardsson N.
Clin Cardiol. 2007 Dec;30(12):624-8.
PMID: 18069679
Suicide and severe mental illnesses. Cohort study within the UK general practice research database.
Osborn D, Levy G, Nazareth I, King M.
Schizophr Res. 2008 Feb;99(1-3):134-8
PMID: 18155881
Costs and effectiveness of travoprost versus a dorzolamide + timolol fixed combination in first-line treatment of glaucoma: analysis conducted on the United Kingdom General Practitioner Research
Database.
Lafuma A, Berdeaux G.
Curr Med Res Opin. 2007 Dec;23(12):3009-16.
PMID: 17958945
The risk of herpes zoster in patients with rheumatoid arthritis in the United States and the United

54.
55.
56.
57.
58.
59.
60.
61.
Kingdom.
Smitten AL, Choi HK, Hochberg MC, Suissa S, Simon TA, Testa MA, Chan KA.
Arthritis Rheum. 2007 Dec 15;57(8):1431-8.
PMID: 18050184
Lifestyle variables and the risk of myocardial infarction in the General Practice Research Database.
Delaney JA, Daskalopoulou SS, Brophy JM, Steele RJ, Opatrny L, Suissa S.
BMC Cardiovasc Disord. 2007 Dec 18;7(1):38
PMID: 18088433
The risk of mortality in patients with psoriasis: results from a population-based study.
Gelfand JM, Troxel AB, Lewis JD, Kurd SK, Shin DB, Wang X, Margolis DJ, Strom BL.
Arch Dermatol. 2007 Dec;143(12):1493-9.
PMID: 18086997
Incidence and risk factors for psoriasis in the general population.
Huerta C, Rivero E, Rodríguez LA.
Arch Dermatol. 2007 Dec;143(12):1559-65.
PMID: 18087008
Upper respiratory tract infection in household contacts of acne patients.
Bowe WP, Hoffstad O, Margolis DJ.
Dermatology. 2007;215 (3):213-8.
PMID: 17823518
Endoscopic findings in a cohort of newly diagnosed gastroesophageal reflux disease patients registered in a
UK primary care database .
Ruigómez A, Rodríguez LA, Wallander MA, Johansson S, Dent J.
Dis Esophagus. 2007;20(6):504-9.
PMID: 17958726
Morbidity Associated With Sleep Disorders in Primary Care: A Longitudinal Cohort Study.
Wallander MA, Johansson S, Ruigómez A, García Rodríguez LA, Jones R.
Prim Care Companion J Clin Psychiatry. 2007;9(5):338-345.
PMID: 17998952
Use of a primary care database to determine trends in genital chlamydia testing, diagnostic episodes and management in UK general practice, 1990-2004.
Hughes G, Williams T, Simms I, Mercer C, Fenton K, Cassell J.
Sex Transm Infect. 2007 Jul;83(4):310-3. Epub 2007 Mar 14.
PMID: 17360731
1.
2.
Incidence of clinically diagnosed systemic lupus erythematosus 1992-1998 using the UK General Practice
Research Database.
Nightingale AL, Farmer RD, de Vries CS
Pharmacoepidemiol Drug Saf. 2006 Sep;15(9):656-61.
PMID: 16389657
Hormone replacement therapy and acute myocardial infarction: a large observational study exploring the influence of age.
Kim J, Evans S, Smeeth L, Pocock S.
Int J Epidemiol. 2006 Jun;35(3):731-8
PMID: 16394112

9.
3.
4.
5.
6.
7.
8.
10.
11.
12.
Incidence of diagnosed polymyalgia rheumatica and temporal arteritis in the United Kingdom, 1990 to
2001.
Smeeth L, Cook C, Hall AJ.
Ann Rheum Dis. 2006 Aug;65(8):1093-8
PMID: 16414971
Incidence of common compressive neuropathies in primary care.
Latinovic R, Gulliford MC, Hughes RA.
J Neurol Neurosurg Psychiatry. (2006); 77: 263-265
PMID: 16421136
Glucocorticoid use, other associated factors, and the risk of tuberculosis.
Jick SS, Lieberman ES, Rahman MU, Choi HK.
Arthritis Rheum. 2006 Feb 15;55(1):19-26
PMID: 16463407
Risk of schizophrenia in people with coeliac disease, ulcerative colitis and Crohn's disease: a general population-based study.
West J, Logan RF, Hubbard RB, Card TR.
Aliment Pharmacol Ther.(2006); 23: 71-4.
PMID: 16393282
Myocardial infarction risk and hormone replacement: differences between products. de Vries CS, Bromley SE, Farmer RD.
Maturitas. 2006 Feb 20;53(3):343-50. Epub 2005 Jul 22.
PMID: 16040209
Allergy, histamine 1 receptor blockers, and the risk of multiple sclerosis.
Alonso A, Jick SS, Hernan MA
Neurology. (2006) Feb 28; 66: 572-5.
PMID: 16505314
Risk and predictors of fatigue after infectious mononucleosis in a large primary-care cohort.
Petersen I, Thomas JM, Hamilton WT, White PD.
QJM. (2006); 99(1): 49-55. Epub 2005 Dec 5.
PMID: 16330591
Trends in sexually transmitted infections in general practice 1990-2000: population based study using data from the UK general practice research database.
Cassell JA, Mercer CH, Sutcliffe L, Petersen I, Islam A, Brook MG, Ross JD, Kinghorn GR, Simms I, Hughes
G, Majeed A, Stephenson JM, Johnson AM, Hayward AC.
BMJ. 2006 Feb 11;332(7537):332-4
PMID: 16439371
Prevalence of inadequate glycemic control among patients with type 2 diabetes in the United Kingdom general practice research database: A series of retrospective analyses of data from 1998 through 2002 .
Fox KM, Gerber Pharmd RA, Bolinder B, Chen J, Kumar S.
Clin Ther. 2006 Mar;28(3):388-95.
PMID: 16750453
Simulation of the Syst-Eur randomized control trial using a primary care electronic medical record was feasible.
Tannen RL, Weiner MG, Marcus SM
J Clin Epidemiol. (2006) Mar; 59: 254-64.
PMID: 16488356
Consultations for middle ear disease, antibiotic prescribing and risk factors for reattendance: a case-

13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23. linked cohort study.
Williamson I, Benge S, Mullee M, Little P.
Br J Gen Pract. (2006) Mar; 56: 170-5.
PMID: 16536956
Upper gastrointestinal complications among users of paracetamol.
Gonzalez-Perez A, Rodriguez LA
Basic Clin Pharmacol Toxicol. (2006) Mar; 98: 297-303
PMID: 16611205
An algorithm to derive a numerical daily dose from unstructured text dosage instructions.
Shah AD, Martinez C.
Pharmacoepidemiol Drug Saf. 2006 Mar;15(3):161-6.
PMID: 16170830
Headache and migraine in primary care: consultation, prescription, and referral rates in a large population.
Latinovic R, Gulliford M, Ridsdale L.
J Neurol Neurosurg Psychiatry. 2006 Mar;77(3):385-7.
PMID: 16484650
All-cause mortality rates in patients with type 1 diabetes mellitus compared with a non-diabetic population from the UK general practice research database, 1992-1999.
Soedamah-Muthu SS, Fuller JH, Mulnier HE, Raleigh VS, Lawrenson RA, Colhoun HM.
Diabetologia. (2006) Apr; 49: 660-6. Epub 2006 Jan 24 .
PMID: 16432708
Is there cross-reactivity between penicillins and cephalosporins?
Apter AJ, Kinman JL, Bilker WB, Herlim M, Margolis DJ, Lautenbach E, Hennessy S, Strom BL
Am J Med. (2006) Apr; 119: 354.e11-9.
PMID: 16564780
High risk of cardiovascular disease in patients with type 1 diabetes in the U.K.: a cohort study using the general practice research database.
Soedamah-Muthu SS, Fuller JH, Mulnier HE, Raleigh VS, Lawrenson RA, Colhoun HM.
Diabetes Care. (2006) Apr; 29: 798-804.
PMID: 16567818
Antibiotic Use and Risk of Multiple Sclerosis.
Alonso A, S Jick S, Jick H, Hernan MA.
Am J Epidemiol. 2006 Jun 1;163(11):997-1002.
PMID: 16597708
Nonsteroidal anti-inflammatory drugs and the incidence of Parkinson disease.
Hernan MA, Logroscino G, Garcia Rodriguez LA.
Neurology. (2006) Apr 11; 66: 1097-9.
PMID: 16606925
Use of first- and second-generation cyclooxygenase-2-selective nonsteroidal antiinflammatory drugs and risk of acute myocardial infarction .
Andersohn F, Suissa S, Garbe E.
Circulation. (2006) Apr 25; 113: 1950-7. Epub 2006 Apr 17.
PMID: 16618816
Chest pain in general practice: incidence, comorbidity and mortality.
Ruigomez A, Rodriguez LA, Wallander MA, Johansson S, Jones R.
Fam Pract. (2006) Apr; 23: 167-74. Epub 2006 Feb 3.
PMID: 16461444

24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
Childhood-Onset Arthritis is Associated with an Elevated Risk of Fracture: A Population-Based Study
Using the General Practice Research Database.
Burnham JM, Shults J, Weinstein R, Lewis JD, Leonard MB.
Ann Rheum Dis. 2006 Aug;65(8):1074-9
PMID: 16627541
Epidemiology and treatment of neuropathic pain: the UK primary care perspective.
Hall GC, Carroll D, Parry D, McQuay HJ.
Pain. 2006 May;122(1-2):156-62. Epub 2006 Mar 20.
PMID: 16545908
Nonsteroidal anti-inflammatory drugs and risk of first hospital admission for heart failure in the general population.
Huerta C, Varas-Lorenzo C, Castellsague J, Garcia Rodriguez LA.
Heart. 2006 Nov;92(11):1610-5
PMID: 16717069
Systemic lupus erythematosus prevalence in the U.K.: methodological issues when using the General
Practice Research Database to estimate frequency of chronic relapsing-remitting disease.
Nightingale AL, Farmer RD, de Vries CS.
Pharmacoepidemiol Drug Saf. 2007 Feb;16(2):144-51
PMID: 16700093
Acute gastroenteritis is followed by an increased risk of inflammatory bowel disease.
Garcia Rodriguez LA, Ruigomez A, Panes J.
Gastroenterology. 2006 May;130(6):1588-94.
PMID: 16697722
Use of antiepileptic drugs and risk of fractures: case-control study among patients with epilepsy.
Souverein PC, Webb DJ, Weil JG, Van Staa TP, Egberts AC.
Neurology. 2006 May 9;66(9):1318-24.
PMID: 16682661
Hormone replacement therapy and cataract: a population-based case-control study.
Aina FO, Smeeth L, Hubbard R, Hurt LS, Fletcher AE.
Eye. 2006 Apr;20(4):417-22.
PMID: 15846385
Mortality in people with type 2 diabetes in the UK.
Mulnier HE, Seaman HE, Raleigh VS, Soedamah-Muthu SS, Colhoun HM, Lawrenson RA.
Diabet Med. 2006 May; 23(5):516-21 .
PMID: 16681560
Bell's palsy and parenteral inactivated influenza vaccine.
Stowe J, Andrews N, Wise L, Miller E.
Hum Vaccin. 2006 May-Jun;2(3):110-2. Epub 2006 May 11.
PMID: 17012908
Statin therapy and reduced risk of pneumonia in patients with diabetes. van de Garde EM, Hak E, Souverein PC, Hoes AW, van den Bosch JM, Leufkens HG.
Thorax. 2006 Nov;61(11):957-61
PMID: 16809409
No association between immunization and Guillain-Barre syndrome in the United Kingdom, 1992 to 2000.
Hughes RA, Charlton J, Latinovic R, Gulliford MC.
Arch Intern Med. 2006 Jun 26;166(12):1301-4.
PMID: 16801513

35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
Discontinuation of antihypertensive drugs among newly diagnosed hypertensive patients in UK general practice.
Burke TA, Sturkenboom MC, Lu SE, Wentworth CE, Lin Y, Rhoads GG.
J Hypertens. 2006 Jun;24(6):1193-200.
PMID: 16685222
Difference in risks of allergic reaction to sulfonamide drugs based on chemical structure.
Verdel BM, Souverein PC, Egberts AC, Leufkens HG.
Ann Pharmacother. 2006 Jun;40(6):1040-6. Epub 2006 May 30.
PMID: 16735666
Risk of aplastic anemia in patients using antiepileptic drugs.
Handoko KB, Souverein PC, van Staa TP, Meyboom RH, Leufkens HG, Egberts TC, van den Bemt PM.
Epilepsia. 2006 Jul;47(7):1232-6.
PMID: 16886988
The impact of dosing frequency on compliance and persistence with bisphosphonates among postmenopausal women in the UK: evidence from three databases.
Brankin E, Walker M, Lynch N, Aspray T, Lis Y, Cowell W.
Curr Med Res Opin. 2006 Jul;22(7):1249-56.
PMID: 16834823
Cyclooxygenase-2 selective nonsteroidal anti-inflammatory drugs and the risk of ischemic stroke: a nested case-control study.
Andersohn F, Schade R, Suissa S, Garbe E.
Stroke. 2006 Jul;37(7):1725-30. Epub 2006 May 25.
PMID: 16728684
Incidence of Guillain-Barre syndrome among patients with Campylobacter infection: a general practice research database study.
Tam CC, Rodrigues LC, Petersen I, Islam A, Hayward A, O'Brien SJ.
J Infect Dis. 2006 Jul 1;194(1):95-7. Epub 2006 May 26.
PMID: 16741887
Diabetes mellitus and antipsychotic treatment in the United Kingdom.
Carlson C, Hornbuckle K, DeLisle F, Kryzhanovskaya L, Breier A, Cavazzoni P.
Eur Neuropsychopharmacol. 2006 Jul;16(5):366-75. Epub 2005 Dec 13.
PMID: 16356695
Reducing variation in antibacterial prescribing rates for 'cough/cold' and sore throat between 1993 and
2001: regional analyses using the general practice research database.
Smith S, Smith GE, Heatlie H, Bashford JN, Ashcroft DM, Verlander NQ, Duckworth GJ, Mason B, Smyth B,
Maxwell S.
Public Health. 2006 Aug;120(8):752-9. Epub 2006 Jul 7 .
PMID: 16828131
Epidemiology, prescribing patterns and resource use associated with overactive bladder in UK primary care.
Odeyemi IA, Dakin HA, O'Donnell RA, Warner J, Jacobs A, Dasgupta P.
Int J Clin Pract. 2006 Aug;60(8):949-58.
PMID: 16893437
Safety of medications prescribed before and during early pregnancy in a cohort of 81,975 mothers from the UK General Practice Research Database.
Hardy JR, Leaderer BP, Holford TR, Hall GC, Bracken MB.
Pharmacoepidemiol Drug Saf. 2006 Aug;15(8):555-64.

45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
PMID: 16767799
Cardioprotective aspirin users and their excess risk of upper gastrointestinal complications.
Hernandez-Diaz S, Garcia Rodriguez LA.
BMC Med. 2006 Sep 20;4(1):22
PMID: 16987411
Comparison of gastro-oesophageal reflux disease and heartburn diagnoses in UK primary care.
Ruigomez A, Garcia Rodriguez LA, Wallander MA, Johansson S, Dent J.
Curr Med Res Opin. 2006 Sep;22(9):1661-8.
PMID: 16968569
The impact of over-the-counter simvastatin on the number of statin prescriptions in the United Kingdom: a view from the General Practice Research Database.
Filion KB, Chris Delaney JA, Brophy JM, Ernst P, Suissa S.
Pharmacoepidemiol Drug Saf. 2007 Jan;16(1):1-4
PMID: 16953516
Physical and psychological co-morbidity in irritable bowel syndrome: a matched cohort study using the
General Practice Research Database.
Jones R, Latinovic R, Charlton J, Gulliford M.
Aliment Pharmacol Ther. 2006 Sep 1;24(5):879-86.
PMID: 16918893
Is an internal comparison better than using national data when estimating mortality in longitudinal studies?
Card TR, Solaymani-Dodaran M, Hubbard R, Logan RF, West J.
J Epidemiol Community Health. 2006 Sep;60(9):819-21.
PMID: 16905729
Pneumococcal polysaccharide vaccine uptake in England, 1989-2003, prior to the introduction of a vaccination programme for older adults.
Noakes K, Pebody RG, Gungabissoon U, Stowe J, Miller E.
J Public Health (Oxf). 2006 Sep;28(3):242-7. Epub 2006 Jul 4.
PMID: 16820432
Hormone therapy and cerebrovascular events: a population-based nested case-control study.
Arana A, Varas C, Gonzalez-Perez A, Gutierrez L, Bjerrum L, Garcia Rodriguez LA.
Menopause. 2006 Sep-Oct;13(5):730-6.
PMID: 16946686
Nonsteroidal antiinflammatory drugs and acute myocardial infarction in patients with no major risk factors.
Jick H, Kaye JA, Russmann S, Jick SS.
Pharmacotherapy. 2006 Oct;26(10):1379-87.
PMID: 16999647
Clinical assessment of the long-term risk of fracture in patients with rheumatoid arthritis. van Staa TP, Geusens P, Bijlsma JW, Leufkens HG, Cooper C.
Arthritis Rheum. 2006 Oct;54(10):3104-12.
PMID: 17009229
Risk of myocardial infarction in patients with psoriasis.
Gelfand JM, Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB.
JAMA. 2006 Oct 11;296(14):1735-41.
PMID: 17032986
Reanalysis of two studies with contrasting results on the association between statin use and fracture risk:

55.
56.
57. the General Practice Research Database. de Vries F, de Vries C, Cooper C, Leufkens B, van Staa TP.
Int J Epidemiol. 2006 Oct;35(5):1301-8.
PMID: 17053011
The risk of lymphoma in patients with psoriasis.
Gelfand JM, Shin DB, Neimann AL, Wang X, Margolis DJ, Troxel AB.
J Invest Dermatol. 2006 Oct;126(10):2194-201. Epub 2006 Jun 1.
PMID: 16741509
Age-related changes in consultations and antibiotic prescribing for acute respiratory infections, 1995-2000.
Data from the UK General Practice Research Database.
Ashworth M, Charlton J, Latinovic R, Gulliford M.
J Clin Pharm Ther. 2006 Oct;31(5):461-7.
PMID: 16958824
58.
Fracture risk in people with primary biliary cirrhosis: a population-based cohort study .
Solaymani-Dodaran M, Card TR, Aithal GP, West J.
Gastroenterology. 2006 Dec;131(6):1752-7. Epub 2006 Sep 8.
PMID: 17087953
59.
Prevalence of contraindicated medical conditions and use of precluded medications in patients with painful neuropathic disorders prescribed amitriptyline
Gore M, Dukes E, Rowbotham D, Tai KS, Leslie DL.
.
Pain Pract. 2006 Dec;6(4):265-72.
PMID: 17129307
Incidence and risk factors for herpes zoster among patients with inflammatory bowel disease .
60.
61. Esophageal stricture: incidence, treatment patterns, and recurrence rate.
Ruigomez A, Garcia Rodriguez LA, Wallander MA, Johansson S, Eklund S.
Am J Gastroenterol. 2006 Dec; 101 (12) : 2685-92.
PMID: 17227515
Gupta G, Lautenbach E, Lewis JD.
Clin Gastroenterol Hepatol. 2006 Dec;4(12):1483-90.
PMID: 17162240
1.
2.
3.
Increased Utilization of Primary Care 5 Years Before Diagnosis of Type 2 Diabetes: A matched cohort study.
Gulliford MC, Charlton J, Latinovic R.
Diabetes Care. (2005) Jan; 28(1): 47-52.
PMID: 15616232
Antidiabetic drugs and heart failure risk in patients with type 2 diabetes in the u.k. Primary care setting.
Maru S, Koch GG, Stender M, Clark D, Gibowski L, Petri H, White AD, Simpson RJ Jr.
Diabetes Care. (2005) Jan; 28(1): 20-6.
PMID: 15616228
Breast cancer risk among users of antidepressant medications.
Gonzalez-Perez A, Garcia Rodriguez LA.
Epidemiology. (2005) Jan; 16(1): 101-5.
PMID: 15613952
Incidence of fractures among epilepsy patients: a population-based retrospective cohort study in the General Practice Research Database.

7.
9.
4. Souverein PC, Webb DJ, Petri H, Weil J, Van Staa TP, Egberts T.
Epilepsia. (2005) Feb;46(2):304-10.
PMID: 15679512
5.
Autoimmune cholestatic liver disease in people with coeliac disease: a population-based study of their association.
Lawson A, West J, Aithal GP, Logan RF.
6.
8.
10.
11.
12.
13.
14.
Aliment Pharmacol Ther. (2005) Feb 15;21(4):401-5.
PMID: 15709990
Time trends in eating disorder incidence.
Currin L, Schmidt U, Treasure J, Jick H.
Br J Psychiatry. (2005) Feb;186:132-5.
PMID: 15684236
Trends in antihypertensive and lipid-lowering therapy in subjects with type II diabetes: clinical effectiveness or clinical discretion?
Gulliford MC, Charlton J, Latinovic R.
J Hum Hypertens. (2005) Feb; 19(2): 111-7.
PMID: 15361893
Antidepressant treatment and the risk of fatal and non-fatal self harm in first episode depression: nested case-control study.
Martinez C, Rietbrock S, Wise L, Ashby B, Chick J, Moseley J, Evans S, Gunnell D.
BMJ (2005), Feb 19;330(7488):389
PMID: 15718538
No risk of drug-associated liver injury with alpha(1)-adrenoreceptor blocking agents in men with BPH: results from an observational study using the GPRD.
Clifford GM, Logie J, Farmer RD.
Pharmacoepidemiol Drug Saf. (2005) Feb;14(2):75-80
PMID: 15386708
Gout epidemiology: results from the UK General Practice Research Database, 1990-1999.
Mikuls TR, Farrar JT, Bilker WB, Fernandes S, Schumacher HR Jr, Saag KG.
Ann Rheum Dis. (2005) Feb; 64(2):267-72
PMID: 15647434
Nonsteroidal anti-inflammatory drugs and risk of ARF in the general population.
Huerta C, Castellsague J, Varas-Lorenzo C, Garcia Rodriguez LA.
Am J Kidney Dis. (2005) Mar;45(3):531-9.
PMID: 15754275
A simple score for estimating the long-term risk of fracture in patients using oral glucocorticoids. van Staa TP, Geusens P, Pols HA, de Laet C, Leufkens HG, Cooper C.
QJM. (2005) Mar;98(3):191-8.
PMID: 15728400
Tamoxifen-treated breast carcinoma patients and the risk of acute myocardial infarction and newlydiagnosed angina.
Bradbury BD, Lash TL, Kaye JA, Jick SS.
Cancer. (2005) Mar 15;103(6):1114-21.
PMID: 15712362
Incidence and outcome of persons with a clinical diagnosis of heart failure in a general practice population of 696,884 in the United Kingdom. de Giuli F, Khaw KT, Cowie MR, Sutton GC, Ferrari R, Poole-Wilson PA.
Eur J Heart Fail. (2005) Mar 16;7(3):295-302.
PMID: 15718168

15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
Intraclass correlation coefficient and outcome prevalence are associated in clustered binary data.
Gulliford MC, Adams G, Ukoumunne OC, Latinovic R, Chinn S, Campbell MJ.
J Clin Epidemiol. (2005) Mar;58(3):246-51.
PMID: 15718113
Incidence, prevalence and management of lower urinary tract symptoms in men in the UK.
Logie J, Clifford GM, Farmer RD.
BJU Int. (2005) Mar;95(4):557-62.
PMID: 15705080
Does lithium therapy protect against the onset of dementia?
Dunn N, Holmes C, Mullee M.
Alzheimer Dis Assoc Disord. (2005) Jan-Mar;19(1):20-2.
PMID: 15764867
A probabilistic cost-effectiveness analysis of escitalopram, generic citalopram and venlafaxine as a first-line treatment of major depressive disorder in the
UK.
Wade AG, Toumi I, Hemels ME.
Curr Med Res Opin. (2005) Apr;21(4):631-42.
PMID: 15899113
Use of antibiotics and risk of breast cancer.
Garcia Rodriguez LA, Gonzalez-Perez A.
Am J Epidemiol. (2005) Apr 1;161(7):616-9.
PMID: 15781950
General population based study of the impact of tricyclic and selective serotonin reuptake inhibitor antidepressants on the risk of acute myocardial infarction.
Tata LJ, West J, Smith C, Farrington P, Card T, Smeeth L, Hubbard R.
Heart. (2005) Apr;91(4):465-71.
PMID: 15772201
Current use of nonsteroidal antiinflammatory drugs and the risk of acute myocardial infarction.
Fischer LM, Schlienger RG, Matter CM, Jick H, Meier CR.
Pharmacotherapy. (2005) Apr;25(4):503-10.
PMID: 15977911
Association between dementia and infectious disease: evidence from a case-control study.
Dunn N, Mullee M, Perry VH, Holmes C.
Alzheimer Dis Assoc Disord. (2005) Apr-Jun;19(2):91-4.
PMID: 15942327
Severity of obstructive airway disease and risk of osteoporotic fracture. de Vries F, van Staa TP, Bracke MS, Cooper C, Leufkens HG, Lammers JW.
Eur Respir J. (2005) May;25(5):879-84.
PMID: 15863646
Glycemic control continues to deteriorate after sulfonylureas are added to metformin among patients with type 2 diabetes.
Cook MN, Girman CJ, Stein PP, Alexander CM, Holman RR.
Diabetes Care. (2005) May;28(5):995-1000.
PMID: 15855556
Hormone replacement therapy and cataract: a population-based case-control study.
Aina FO, Smeeth L, Hubbard R, Hurt LS, Fletcher AE.

25. Eye. (2006) May;20:417-22. Epub 2005 Apr 22.
PMID: 15846385
Respiratory medications and the risk of cardiac arrhythmias.
Huerta C, Lanes SF, Garcia Rodriguez LA.
26. Epidemiology. (2005) May;16(3):360-6.
PMID: 15824553
27.
Antibiotic use and the risk of flare of inflammatory bowel disease.
Aberra FN, Brensinger CM, Bilker WB, Lichtenstein GR, Lewis JD.
Clin Gastroenterol Hepatol. (2005) May;3(5):459-65.
PMID: 15880315
28.
29.
Antibiotic prescribing in general practice and hospital admissions for peritonsillar abscess, mastoiditis, and rheumatic fever in children: time trend analysis.
Sharland M, Kendal H, Yeates D, Randall A, Hughes G, Glasziou P, Mant D.
BMJ. 2005 Aug 6;331(7512):328-9
PMID: 15967760
Concerning: 'Why has antibiotic prescribing for respiratory illness declined in primary care? A longitudinal study using the General Practice Research
Database'.
Fleming DM, Ross AM, Cross KW, Kendall H, Elliot AJ.
J Public Health (Oxf). (2005) Jun;27(2):228-9. Epub 2005 Mar 4.
PMID: 15749719
30.
31.
Obtaining optimal control in mild asthma: theory and practice.
Watson L, Kerstjens HA, Rabe KF, Kiri V, Visick GT, Postma DS.
Fam Pract. (2005) Jun;22(3):305-10. Epub 2005 Apr 1.
PMID: 15805133
Prevalence of risk factors for suicide in patients prescribed venlafaxine, fluoxetine, and citalopram.
Mines D, Hill D, Yu H, Novelli L.
Pharmacoepidemiol Drug Saf. (2005 ) Jun;14(6):367-72.
PMID: 15883980
32.
Cigarette smoking and the progression of multiple sclerosis.
Hernan MA, Jick SS, Logroscino G, Olek MJ, Ascherio A, Jick H.
Brain. (2005) Jun;128(Pt 6):1461-5. Epub 2005 Mar 9.
PMID: 15758034
33.
34.
35.
Type 2 diabetes mellitus and the risk of colorectal cancer.
Yang YX, Hennessy S, Lewis JD.
Clin Gastroenterol Hepatol. (2005) Jun;3(6):587-94.
PMID: 15952101
5-aminosalicylate use and colorectal cancer risk in inflammatory bowel disease: a large epidemiological study. van Staa TP, Card TR, Leufkens HG, Logan RF.
Gut. 2005 Nov;54(11):1573-8. Epub 2005 Jun 30
PMID: 15994215
Utility of routinely acquired primary care data for paediatric disease epidemiology and pharmacoepidemiology.
Helms PJ, Ekins Daukes S, Taylor MW, Simpson CR, McLay JS.
Br J Clin Pharmacol. (2005) Jun;59(6):684-90.
PMID: 15948933
Predictors and prognosis of paroxysmal atrial fibrillation in general practice in the UK.

36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
Ruigomez A, Johansson S, Wallander MA, Garcia Rodriguez LA.
BMC Cardiovasc Disord. (2005) Jul 11;5(1):20.
PMID: 16030083
Case-mix and variation in specialist referrals in general practice.
Sullivan CO, Omar RZ, Ambler G, Majeed A.
Br J Gen Pract. (2005) Jul;55(516):529-33.
PMID: 16004738
Gastroesophageal reflux disease and asthma: a longitudinal study in UK general practice.
Ruigomez A, Rodriguez LA, Wallander MA, Johansson S, Thomas M, Price D.
Chest. (2005) Jul;128(1):85-93.
PMID: 16002920
Cesarean delivery in the United Kingdom: time trends in the general practice research database.
Black C, Kaye JA, Jick H.
Obstet Gynecol. (2005) Jul;106(1):151-5.
PMID: 15994631
Risk of cholestatic liver disease associated with flucloxacillin and flucloxacillin prescribing habits in the
UK: cohort study using data from the UK General Practice Research Database.
Russmann S, Kaye JA, Jick SS, Jick H.
Br J Clin Pharmacol. (2005) Jul;60(1):76-82.
PMID: 15963097
The relationship between time since registration and measured incidence rates in the General Practice Research Database.
Lewis JD, Bilker WB, Weinstein RB, Strom BL.
Pharmacoepidemiol Drug Saf. (2005) Jul;14(7):443-51.
PMID: 15898131
Suboptimal physician adherence to quality indicators for the management of gout and asymptomatic hyperuricaemia: results from the UK General Practice Research
Database (GPRD).
Mikuls TR, Farrar JT, Bilker WB, Fernandes S, Saag KG.
Rheumatology (Oxford). (2005) Aug;44(8):1038-42. Epub 2005 May 3.
PMID: 15870145
The prognosis of different fatigue diagnostic labels: a longitudinal survey.
Hamilton WT, Gallagher AM, Thomas JM, White PD.
Fam Pract. (2005) Aug;22(4):383-8. Epub 2005 Apr 1.
PMID: 15805126
Cholecystectomy and the risk of colorectal cancer.
Shao T, Yang YX.
Am J Gastroenterol. (2005) Aug;100(8):1813-20.
PMID: 16086719
Inhaled corticosteroids in chronic obstructive pulmonary disease: results from two observational designs free of immortal time bias.
Kiri VA, Pride NB, Soriano JB, Vestbo J.
Am J Respir Crit Care Med. (2005) Aug 15;172(4):460-4. Epub 2005 May 18.
PMID: 15901610
New cases of diabetes mellitus in England and Wales, 1994-1998: Database study.
Ryan R, Newnham A, Khunti K, Majeed A.
Public Health. (2005); 119: 892-9.
Epub 2005 Aug 2.
PMID: 16083928

47.
48.
49.
50.
51.
52.
53.
54.
55.
56.
57.
Obesity and the risk of prostate cancer (United States).
Bradbury BD, Wilk JB, Kaye JA.
Cancer Causes Control. (2005) Aug;16(6):637-41.
PMID: 16049801
An algorithm to derive a numerical daily dose from unstructured text dosage instructions.
Shah AD, Martinez C.
Pharmacoepidemiol Drug Saf. (2005) Sep 19; [Epub ahead of print]
Inhaled corticosteroids are more effective in COPD patients when used with LABA than with SABA.
Kiri VA, Bettoncelli G, Testi R, Viegi G.
Respir Med. (2005) Sep;99(9):1115-24. Epub 2005 Mar 21 .
PMID: 15921904
Antidiabetic therapy and the risk of heart failure in type 2 diabetic patients: an independent effect or confounding by indication.
Koro CE, Bowlin SJ, Weiss SR.
Pharmacoepidemiol Drug Saf. ( 2005 ); Oct;14(10):697-703 .
PMID: 15654719
Influenza vaccine uptake and distribution in England and Wales using data from the General Practice
Research Database, 1989/90-2003/04.
Joseph C, Goddard N, Gelb D
J Public Health (Oxf). (2005) ; 27: 371-7. Epub 2005 Oct 5
PMID: 16207735
The changing use of disease-modifying anti-rheumatic drugs in individuals with rheumatoid arthritis from the United Kingdom General Practice Research Database.
Edwards CJ, Arden NK, Fisher D, Saperia JC, Reading I, Van Staa TP, Cooper C.
Rheumatology (Oxford). 2005 Nov;44(11):1394-8. Epub 2005 Jul 19
PMID: 16030083
Diabetes mellitus and antipsychotic treatment in the United Kingdom.
Carlson C, hornbuckle K, Delisle F, Kryzhanovskaya L, breier A, Cavazzoni P.
Eur Neuropsychopharmacol. 2006 Jul;16(5):366-75
PMID: 16356695
Risk of hip/femur fractures in patients using antipsychotics.
Hugenholtz GW, Heerdink ER, van Staa TP, Nolen WA, Egberts AC.
Bone. (2005) Dec; 37: 864-70. Epub 2005 Aug 19
PMID: 16111927
Drug interactions and risk of acute bleeding leading to hospitalisation or death in patients with chronic atrial fibrillation treated with warfarin.
Gasse C, Hollowell J, Meier CR, Haefeli WE.
Thromb Haemost. (2005); 94: 537-43.
PMID: 16268469
Prostate cancer risk among men with diabetes mellitus (Spain).
Gonzalez-Perez A, Garcia Rodriguez LA.
Cancer Causes Control. (2005); 16: 1055-8.
PMID: 16184470
Use of gastric acid-suppressive agents and the risk of community-acquired Clostridium difficile-associated disease.
Dial S, Delaney JA, Barkun AN, Suissa S.
JAMA. (2005); 294: 2989-95.
PMID: 16414946
Mortality associated with Barrett's esophagus and gastroesophageal reflux disease diagnoses-a population-

58.
59.
60.
61.
62.
63.
64.
65.
66.
67.
68. based cohort study .
Solaymani-Dodaran M, Logan RF, West J, Card T.
Am J Gastroenterol. (2005); 100: 2616-21.
PMID: 16393209
Prevalence and treatment of psoriasis in the United Kingdom: a population-based study.
Gelfand JM, Weinstein R, Porter SB, Neimann AL, Berlin JA, Margolis DJ.
Arch Dermatol. (2005); 141: 1537-41.
PMID: 16365254
Substance misuse and psychiatric illness: prospective observational study using the general practice research database.
Frisher M, Crome I, Macleod J, Millson D, Croft P.
J Epidemiol Community Health. (2005); 59: 847-50.
PMID: 16166357
Recent use of oral contraceptives and the risk of multiple sclerosis .
Alonso A, Jick SS, Olek MJ, Ascherio A, Jick H, Hernan MA
Arch Neurol. (2005); 62: 1362-5 .
PMID: 16157743
Increased risk for demyelinating diseases in patients with inflammatory bowel disease.
Gupta G, Gelfand JM, Lewis JD.
Gastroenterology. (2005); 129: 819-26.
PMID: 16143121
Antibiotics and the risk of breast cancer.
Kaye JA, Jick H.
Epidemiology. (2005); 16: 688-90 .
PMID: 16135947
A case control study of age related macular degeneration and use of statins.
Smeeth L, Cook C, Chakravarthy U, Hubbard R, Fletcher AE.
Br J Ophthalmol. (2005); 89: 1171-5.
PMID: 16113375
Patterns of Comorbidities in Newly Diagnosed COPD and Asthma in Primary Care.
Soriano JB, Visick GT, Muellero va H, Payvandi N, Hansell AL.
Chest. (2005); 128:2099-107.
PMID: 16236861
Antibiotic treatment of acne may be associated with upper respiratory tract infections .
Margolis DJ, Bowe WP, Hoffstad O, Berlin JA.
Arch Dermatol. (2005); 141: 1132-6
PMID: 16172310
Variations in antibiotic prescribing and consultation rates for acute respiratory infection in UK general practices 1995-2000.
Ashworth M, Charlton J, Ballard K, Latinovic R, Gulliford M.
Br J Gen Pract.(2005); 55: 603-8.
PMID: 16105368
Tibolone and endometrial cancer: a cohort and nested case-control study in the
UK. de Vries CS, Bromley SE, Thomas H, Farmer RD.
Drug Saf. (2005);28(3):241-9.
PMID: 15733028

9.
7.
1.
2.
3.
4.
5.
6.
8.
10.
A population-based study of the incidence, cause, and severity of anaphylaxis in the United Kingdom.
Peng MM, Jick H.
Arch Intern Med. (2004) Feb 9; 164(3):317-9.
PMID: 14769628
Developing a large electronic primary care database (Doctors' Independent Network) for research.
Carey IM, Cook DG, De Wilde S, Bremner SA, Richards N, Caine S, Strachan DP, Hilton SR.
Int J Med Inform. (2004) Jun 15; 73(5): 443-53.
PMID: 15171985
Risk of extra-oesophageal malignancies and colorectal cancer in Barrett's oesophagus and gastrooesophageal reflux.
Solaymani-Dodaran M, Logan RF, West J, Card T, Coupland C.
Scand J Gastroenterol. (2004) Jul; 39(7): 680-5.
PMID: 15370691
Use of oral glucocorticoids and risk of cardiovascular and cerebrovascular disease in a population based case-control study.
Souverein PC, Berard A, Van Staa TP, Cooper C, Egberts AC, Leufkens HG, Walker BR.
Heart. (2004) Aug; 90(8): 859-65.
PMID: 15253953
Breast cancer incidence and use of antihypertensive medication in women.
Gonzalez-Perez A, Ronquist G, Garcia Rodriguez LA.
Pharmacoepidemiol Drug Saf. (2004) Aug; 13(8): 581-5.
PMID: 15317040
A comparison of the recording of 30 common childhood conditions in the Doctor's Independent Network and General Practice Research Databases.
De Wilde S, Carey IM, Bremner SA, Richards N, Hilton SR, Strachan DP, Cook DG.
Health Stat Q. 2004 Summer;(22):21-31.
PMID: 15704391
Why has antibiotic prescribing for respiratory illness declined in primary care? A longitudinal study using the General Practice Research Database.
Ashworth M, Latinovic R, Charlton J, Cox K, Rowlands G, Gulliford M.
J Public Health (Oxf).(2004) Sep; 26(3): 268-74.
PMID: 15454595
Tamoxifen and cataracts: a null association.
Bradbury BD, Lash TL, Kaye JA, Jick SS.
Breast Cancer Res Treat. (2004) Sep; 87(2): 189-96.
PMID: 15377843
Use of beta-blockers and risk of fractures.
Schlienger RG, Kraenzlin ME, Jick SS, Meier CR.
JAMA.(2004) Sep 15; 292(11): 1326-32.
PMID: 15367554
Recombinant hepatitis B vaccine and the risk of multiple sclerosis: a prospective study.
Hernan MA, Jick SS, Olek MJ, Jick H.
Neurology. (2004) Sep 14; 63(5): 838-42.
PMID: 15365133
MMR vaccination and pervasive developmental disorders: a case-control study.
Smeeth L, Cook C, Fombonne E, Heavey L, Rodrigues LC, Smith PG, Hall AJ.

11. Lancet. (2004) Sep 11; 364(9438): 963-9.
PMID: 15364187
Epidemiology of restless legs syndrome as diagnosed in UK primary care.
Van De Vijver DA, Walley T, Petri H.
12. Sleep Med. (2004) Sep; 5(5): 435-40.
PMID: 15341887
13.
Malignancy and mortality in people with coeliac disease: population based cohort study.
West J, Logan RF, Smith CJ, Hubbard RB, Card TR.
BMJ. (2004) Sep 25; 329(7468): 716-9. Epub 2004 Jul 21.
PMID: 15269095
14.
Comparative cardiac safety of low-dose thioridazine and low-dose haloperidol.
BL
Hennessy S, Bilker WB, Knauss JS, Kimmel SE, Margolis DJ, Morrison MF, Reynolds RF, Glasser DB, Strom
Br J Clin Pharmacol. (2004); 58: 81-7. Erratum in: Br J Clin Pharmacol. (2004) Aug; 58(2):228.
PMID: 15206997
Natural history of gastro-oesophageal reflux disease diagnosed in general practice.
Ruigomez A, Garcia Rodriguez LA, Wallander MA, Johansson S, Graffner H, Dent J.
15.
16.
17.
18.
Aliment Pharmacol Ther. (2004) Oct 1; 20(7): 751-60.
PMID: 15379835
A prospective study of alcoholism and the risk of Parkinson's disease.
Hernan MA, Logroscino G, Rodriguez LA.
J Neurol. (2004) Oct; 251 Suppl 7: vII14-7.
PMID: 15505749
Insulin therapy and colorectal cancer risk among type 2 diabetes mellitus patients.
Yang YX, Hennessy S, Lewis JD.
Gastroenterology. (2004) Oct; 127(4): 1044-50.
PMID: 15480982
Are inhaled corticosteroids associated with an increased risk of fracture in children? van Staa TP, Bishop N, Leufkens HG, Cooper C.
Osteoporos Int. 2004 Oct;15(10):785-91. Epub 2004 Feb 21.
PMID: 14985948
Rate of first recorded diagnosis of autism and other pervasive developmental disorders in United
19.
20.
Kingdom general practice, 1988 to 2001.
Smeeth L, Cook C, Fombonne PE, Heavey L, Rodrigues LC, Smith PG, Hall AJ.
BMC Med. (2004) Nov 09; 2(1): 39.
PMID: 15535890
Persistency and treatment failure in newly diagnosed open angle glaucoma patients in the United
Kingdom.
Zhou Z, Althin R, Sforzolini BS, Dhawan R.
Br J Ophthalmol. (2004) Nov; 88(11): 1391-4.
21.
22.
PMID: 15489479
Strategies for identifying pregnancies in the automated medical records of the General Practice Research
Database.
Hardy JR, Holford TR, Hall GC, Bracken MB.
Pharmacoepidemiol Drug Saf. (2004) Nov; 13(11): 749-59.
PMID: 15386720
The psychosocial outcome of pregnancy in women with psychotic disorders.
Howard LM, Goss C, Leese M, Appleby L, Thornicroft G.
Schizophr Res. (2004) Nov 1; 71(1): 49-60.

23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
PMID: 15374572
Risk of myocardial infarction and stroke after acute infection or vaccination.
Smeeth L, Thomas SL, Hall AJ, Hubbard R, Farrington P, Vallance P.
N Engl J Med. (2004) Dec 16; 351(25): 2611-8.
PMID: 15602021
What has happened to antimicrobial usage in primary care in the United Kingdom since the SMAC report? - Description of trends in antimicrobial usage using the General Practice Research Database.
Smith GE, Smith S, Heatlie H, Bashford JN, Hawker J, Ashcroft D, Millson D, Verlander NQ, Warren R.
J Public Health (Oxf). (2004) Dec; 26(4): 359-64.
PMID: 15598854
Discontinuation of nonsteroidal anti-inflammatory drug therapy and risk of acute myocardial infarction.
Fischer LM, Schlienger RG, Matter CM, Jick H, Meier CR.
Arch Intern Med. (2004) Dec 13-27; 164(22): 2472-6.
PMID: 15596638
Epidemiology of lower limb fractures in general practice in the United Kingdom.
Kaye JA, Jick H.
Inj Prev. (2004) Dec; 10(6): 368-74.
PMID: 15583259
Incidence of fatigue symptoms and diagnoses presenting in UK primary care from 1990 to 2001.
Gallagher AM, Thomas JM, Hamilton WT, White PD.
J R Soc Med. (2004) Dec; 97(12): 571-5.
PMID: 15574853
The epidemiology of the comorbidity of epilepsy in the general population.
Gaitatzis A, Carroll K, Majeed A, W Sander J.
Epilepsia. (2004) Dec;45(12):1613-22.
PMID: 15571520
A drug utilisation study of antidepressants in children and adolescents using the General Practice
Research Database.
Murray ML, de Vries CS, Wong IC.
Arch Dis Child. (2004) Dec; 89(12): 1098-102.
PMID: 15557040
Prevalence of comorbid psychiatric illness and substance misuse in primary care in England and Wales.
Frisher M, Collins J, Millson D, Crome I, Croft P.
J Epidemiol Community Health. (2004) Dec; 58(12): 1036-41.
PMID: 15547069
Epidemiology of childhood fractures in Britain: a study using the general practice research database.
Cooper C, Dennison EM, Leufkens HG, Bishop N, van Staa TP.
J Bone Miner Res. (2004) Dec; 19(12): 1976-81. Epub 2004 Sep 20.
PMID: 15537440
Seasonal variation in flares of inflammatory bowel disease.
Lewis JD, Aberra FN, Lichtenstein GR, Bilker WB, Brensinger C, Strom BL.
Gastroenterology. (2004); 126: 665-73.
PMID: 14988820
Triptans in migraine: The risks of stroke, cardiovascular disease, and death in practice.
Hall GC, Brown MM, Mo J, MacRae KD.
Neurology. (2004); 62: 563-8 .
PMID: 14981171
The risk of severe depression, psychosis or panic attacks with prophylactic antimalarials.

34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
Meier CR, Wilcock K, Jick SS.
Drug Saf. (2004); 27: 203-13.
PMID: 14756582
Statin use and cancer risk in the General Practice Research Database.
Kaye JA, Jick H
Br J Cancer. (2004); 90: 635-7.
PMID: 14760377
Hip fractures in patients with inflammatory bowel disease and their relationship to corticosteroid use: a population based cohort study.
Card T, West J, Hubbard R, Logan RF.
Gut. (2004); 53: 251-5.
PMID: 14724159
Antibiotic use and the development of Crohn's disease.
Card T, Logan RF, Rodrigues LC, Wheeler JG.
Gut. (2004); 53: 246-50 .
PMID: 14724158
Effect of rheumatoid arthritis or systemic lupus erythematosus on the risk of first-time acute myocardial infarction.
Fischer LM, Schlienger RG, Matter C, Jick H, Meier CR.
Am J Cardiol. (2004); 93: 198-200.
PMID: 14715346
Association between captopril, other antihypertensive drugs and risk of prostate cancer.
Ronquist G, Rodriguez LA, Ruigomez A, Johansson S, Wallander MA, Frithz G, Svardsudd K.
Prostate. (2004); 58: 50-6.
PMID: 14673952
A cohort study of the effectiveness of influenza vaccine in older people, performed using the United kingdom general practice research database.
Mangtani P, Cumberland P, Hodgson CR, Roberts JA, Cutts FT, Hall AJ.
J Infect Dis. (2004); 190: 1-10
PMID: 15195237
Incidence and prevalence of drug-treated attention deficit disorder among boys in the UK.
Jick H, Kaye JA, Black C.
Br J Gen Pract. (2004); 54: 345-7
PMID: 15113516
Validation of the diagnosis of autism in general practitioner records.
Fombonne E, Heavey L, Smeeth L, Rodrigues LC, Cook C, Smith PG, Meng L, Hall AJ.
BMC Public Health. (2004); 4: 5
PMID: 15113435
Represcription of penicillin after allergic-like events.
Apter AJ, Kinman JL, Bilker WB, Herlim M, Margolis DJ, Lautenbach E, Hennessy S, Strom BL.
J Allergy Clin Immunol. (2004); 113: 764-70
PMID: 15100685
5-Alpha reductase inhibition provides superior benefits to alpha blockade by preventing AUR and BPHrelated surgery.
Boyle P, Roehrborn C, Harkaway R, Logie J, de la Rosette J, Emberton M.
Eur Urol. (2004); 45: 620-6
PMID: 15082205
Late-onset seizures as a predictor of subsequent stroke.
Cleary P, Shorvon S, Tallis R .

45. Lancet. (2004); 363: 1184-6
PMID: 15081649
Inverse association between nonsteroidal anti-inflammatory drugs and prostate cancer.
Garcia Rodriguez LA, Gonzalez-Perez A.
46. Cancer Epidemiol Biomarkers Prev. (2004); 13: 649-53
PMID: 15066932
47.
48.
Utilisation of hormone replacement therapy in the United Kingdom. A descriptive study using the general practice research database.
Bromley SE, de Vries CS, Farmer RD.
BJOG. (2004); 111: 369-76
PMID: 15008775
Medical conditions associated with venous leg ulcers.
Margolis DJ, Knauss J, Bilker W.
Br J Dermatol. (2004); 150: 267-73
PMID: 14996097
Pharmaceutical treatment of symptomatic vertebral fractures in primary care.
Torgerson DJ, Sykes D, Puffer S, Brown P, Cooper C.
49.
50.
Ann Rheum Dis. (2004); 63: 853-6
PMID: 15194583
5-aminosalicylic acids and the risk of renal disease: A large british epidemiologic study.
Van Staa TP, Travis S, Leufkens HG, Logan RF.
Gastroenterology. (2004); 126: 1733-9
PMID: 15188168
51.
52.
53.
Ischemic Stroke in Young Women. A Nested Case-Control Study Using the UK General Practice Research
Database.
Nightingale AL, Farmer RD.
Stroke. (2004); 35 : 1574-8
PMID: 15143296
Acute and clinically relevant drug-induced liver injury: a population based case-control study.
De Abajo FJ, Montero D, Madurga M, Rodriguez LA.
Br J Clin Pharmacol. (2004); 58: 71-80
PMID: 15206996
Autism and DPT vaccine in the UK
Kaye JA, Jick H
N Engl J Med (2004); 350 (26): 2722-3
PMID: 15215496
54.
55.
56.
In-vitro fertilisation and childhood retinoblastoma
Bradbury BD, Jick H
Br J Clin Pharmacol. (2004); 58: 209-11.
PMID: 15255804
Antidepressants and the risk of suicidal behaviors
Jick H, Kaye JA, Jick SS
JAMA (2004); 292: 338-343
PMID: 15265848
Vaccination and allergic disease: a birth cohort study.
McKeever TM, Lewis SA, Smith C, Hubbard R.
Am J Public Health. (2004); 94: 985-9
PMID: 15249303

57.
58.
59.
60.
61.
62.
63.
64.
65.
66.
67.
68.
Risk of oesophageal cancer in Barrett's oesophagus and gastro-oesophageal reflux.
Solaymani-Dodaran M, Logan RF, West J, Card T, Coupland C.
Gut. (2004); 53: 1070-4
PMID: 15370691
Risk factors in carpal tunnel syndrome.
Geoghegan JM, Clark DI, Bainbridge LC, Smith C, Hubbard R.
J Hand Surg [Br]. (2004); 29: 315-20
PMID: 15234492
Risk of vascular disease in adults with diagnosed coeliac disease: a population-based study.
West J, Logan RF, Card TR, Smith C, Hubbard R.
Aliment Pharmacol Ther. (2004); 20: 73-9
PMID: 15225173
A cohort study of the effectiveness of influenza vaccine in older people, performed using the United kingdom general practice research database.
Mangtani P, Cumberland P, Hodgson CR, Roberts JA, Cutts FT, Hall AJ.
J Infect Dis. (2004); 190: 1-10
PMID: 15195237
Agreement between GPRD smoking data: a survey of general practitioners and a population-based survey.
Lewis JD, Brensinger C.
Pharmacoepidemiol Drug Saf. (2004); 13: 437-41
PMID: 15269927
Venous thromboembolism associated with cyproterone acetate in combination with ethinyloestradiol
(Dianette(R)): observational studies using the UK General Practice Research Database.
Seaman HE, De Vries CS, Farmer RD.
Pharmacoepidemiol Drug Saf. (2004); 13: 427-36
PMID: 15269926
Application of a propensity score to adjust for channelling bias with NSAIDs
Morant SV, Pettitt D, MacDonald TM, Burke TA, Goldstein JL
Pharmacoepidemiol Drug Saf. (2004); 13: 345-353
PMID: 15170763
Inhaled corticosteroids and the risk of fractures in children and adolescents
Schlienger RG, Jick SS, Meier SR
Pediatrics. (2004); 114: 469-73
PMID: 15286232
Risk of breast cancer among users of aspirin and other anti-inflammatory drugs.
Garcia Rodriguez LA, Gonzalez-Perez A.
Br J Cancer. (2004); 91: 525-9
PMID: 15226764
Statins and newly diagnosed diabetes
Jick SS, Bradbury BD
Br J Clin Pharmacol. (2004); 58: 303-9
PMID: 15327590
Medical event profiling of COPD patients.
Hansell AL, Lam KA, Richardson S, Visick G, Soriano JB
Pharmacoepidemiol Drug Saf. (2004); 13: 547-55
PMID: 15317036
Thimerosal exposure in infants and developmental disorders: a retrospective cohort study in the United
Kingdom does not support a causal association

7.
69.
70.
Andrews N, Miller E, Grant A, Stowe J, Osborne V, Taylor B
Pediatrics (2004); 114: 584-591
PMID: 15342825
Relative cost effectiveness of Depo-Provera, Implanon, and Mirena in reversible long-term hormonal contraception in the UK.
Varney SJ, Guest JF.
Pharmacoeconomics. (2004); 22(17): 1141-51
PMID: 15612832
Current use of selective serotonin reuptake inhibitors and risk of acute myocardial infarction.
Schlienger RG, Fischer LM, Jick H, Meier CR.
Drug Saf. (2004); 27(14): 1157-65.
PMID: 15554748
1.
2.
3.
4.
5.
6.
Temporal trends in orchidopexy, great britain, 1992-1998
Toledano MB, Hansell AL, Jarup L, Quinn M, Jick S, Elliott P
Environ Health Perspect (2003); 111: 129-132
PMID: 12515691
Medical outcome of pregnancy in women with psychotic disorders and their infants in the first year after birth
Howard LM, Goss C, Leese M, Thornicroft G
Br J Psychiatry (2003); 182: 63-67
PMID: 12509320
Incidence of erectile dysfunction and characteristics of patients before and after the introduction of sildenafil in the United Kingdom: cross sectional study with comparison patients.
Kaye JA, Jick H.
Br Med J. (2003); 326: 424-425
PMID: 12595382
Cataract and the use of statins: a case-control study.
Smeeth L, Hubbard R, Fletcher AE
Q J Med (2003); 96: 337-343
PMID: 12702782
Is hormone replacement therapy associated with an increased risk of irritable bowel syndrome?
Ruigomez A, Garcia Rodriguez LA, Johansson S, Wallander MA
Maturitas (2003); 44: 133-140
PMID: 12590009
MMR vaccine and idiopathic thrombocytopaenic purpura
Black C, Kaye JA, Jick H
Br J Clin Pharmacol. (2003); 55: 107-111
PMID: 12534647
Who receives lipid-lowering drugs: the effects of comorbidities and patient characteristics on treatment initiation?
Yang CC, Jick SS, Testa MA
Br J Clin Pharmacol (2003); 55: 288-298
PMID: 12630980
The risk of venous thromboembolism in women prescribed cyproterone acetate in combination with ethinyl estradiol: a nested cohort analysis and case-control study.

9.
8. Seaman HE, Vries CS, Farmer RD.
Hum Reprod. (2003); 18: 522-6
PMID: 12615818
Differences in the use of combined oral contraceptives amongst women with and without acne.
Seaman HE, Vries CS, Farmer RD.
Hum Reprod. (2003); 18: 515-21
PMID: 12615817
10.
11.
Nonsteroidal antiinflammatory drugs as a trigger of clinical heart failure.
Garcia Rodriguez LA, Hernandez-Diaz S.
Epidemiology. (2003); 14: 240-6
PMID: 12606892
Increasing prevalence of asthma in UK primary care during the 1990s.
Soriano JB, Kiri VA, Maier WC, Strachan D
Int J Tuberc Lung Dis. (2003); 7: 415-21
PMID: 12757040
Medical conditions as risk factors for pressure ulcers in an outpatient setting.
Margolis DJ, Knauss J, Bilker W, Baumgarten M.
12.
13.
Age Ageing. (2003); 32: 259-64
PMID: 12720610
Children and the risk of fractures caused by oral corticosteroids. van Staa TP, Cooper C, Leufkens HG, Bishop N.
J Bone Miner Res. (2003); 18: 913-8
PMID: 12733732
14.
15.
16.
Neutropenia and agranulocytosis in England and Wales: incidence and risk factors . van Staa TP, Boulton F, Cooper C, Hagenbeek A, Inskip H, Leufkens HG.
Am J Hematol. (2003); 72: 248-54
PMID: 12666135
Referral of children to specialists in the United States and the United Kingdom.
Forrest CB, Majeed A, Weiner JP, Carroll K, Bindman AB.
Arch Pediatr Adolesc Med. (2003); 15: 279-85
PMID: 12622678
Head lice diagnosed in general practice in the West Midlands between 1993 and 2000: a survey using the
General Practice Research Database.
Smith S, Smith G, Heatlie H, Bashford J, Ashcroft D, Millson D.
Commun Dis Public Health (2003); 6: 139-43
PMID: 12889294
17.
18.
19.
All-Cause Mortality and Vascular Events Among Patients with Rheumatoid Arthritis, Osteoarthritis, or
No Arthritis in the UK General Practice Research Database.
Watson DJ, Rhodes T, Guess HA
J Rheumatol. (2003); 30: 1196-202
PMID: 12784389
The risk of stillbirth in pregnancies before and after the onset of diabetes.
Wood SL, Jick H, Sauve R.
Diabet Med. (2003);20 : 703-707
PMID: 12925047
Channelling bias and the incidence of gastrointestinal haemorrhage in users of meloxicam, coxibs, and older, non-specific non-steroidal anti-inflammatory drugs.
MacDonald TM, Morant SV, Goldstein JL, Burke TA, Pettitt D.
Gut. (2003); 52: 1265-1270

20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
PMID: 12912856
Increased risk of achilles tendon rupture with quinolone antibacterial use, especially in elderly patients taking oral corticosteroids.
Van der Linden PD, Sturkenboom MC, Herings RM, Leufkens HM, Rowlands S, Stricker BH.
Arch Intern Med (2003); 163: 1801-7
PMID: 12912715
The proportional Venn diagram of obstructive lung disease: two approximations from the United States and the United Kingdom.
Soriano JB, Davis KJ, Coleman B, Visick G, Mannino D, Pride NB.
Chest (2003); 124: 474-81
PMID: 12907531
Fracture risk in people with celiac disease: a population-based cohort study.
West J, Logan RF, Card TR, Smith C, Hubbard R.
Gastroenterology. (2003); 125: 429-36
PMID: 12891545
The incidence of bleeding complications associated with warfarin treatment in general practice in the
United Kingdom.
Hollowell J, Ruigomez A, Johansson S, Wallander MA, Garcia-Rodriguez LA.
Br J Gen Pract. (2003); 53: 312-4
PMID: 12879832
Discontinuation and switching of therapy after initiation of lipid-lowering drugs: the effects of comorbidities and patient characteristics.
Yang CC, Jick SS, Testa MA.
Br J Clin Pharmacol. (2003); 56: 84-91
PMID: 12848779
Exposure to tricyclic and selective serotonin reuptake inhibitor antidepressants and the risk of hip fracture.
Hubbard R, Farrington P, Smith C, Smeeth L, Tattersfield A.
Am J Epidemiol. (2003); 158: 77-84
PMID: 12835289
Absence of cross-reactivity between sulfonamide antibiotics and sulfonamide nonantibiotics.
Strom BL, Schinnar R, Apter AJ, Margolis DJ, Lautenbach E, Hennessy S, Bilker WB, Pettitt D.
N Engl J Med. (2003); 349: 1628-35
PMID: 14573734
The differences between ACE inhibitor-treated and calcium channel blocker-treated hypertensive patients.
McInnes GT.
J Clin Hypertens (Greenwich). (2003); 5: 337-44
PMID: 14564134
Antihypertensive treatment and erectile dysfunction in a cohort of type II diabetes patients.
Blumentals WA, Brown RR, Gomez-Caminero A.
Int J Impot Res. (2003); 15: 314-7
PMID: 14562130
Users of oral steroids are at a reduced risk of developing irritable bowel syndrome.
Huerta C, Garcia Rodriguez LA, Wallander MA, Johansson S.
Pharmacoepidemiol Drug Saf. (2003); 12: 583-8
PMID: 14558181
The risk of liver disorders in women prescribed cyproterone acetate in combination with ethinyloestradiol
(Dianette): a nested case-control study using the GPRD.

30. Seaman HE, de Vries CS, Farmer RD.
Pharmacoepidemiol Drug Saf. (2003); 12: 541-50
PMID: 14558177
31.
Implications of the problem orientated medical record (POMR) for research using electronic GP databases: a comparison of the Doctors Independent Network Database (DIN) and the General Practice
Research Database (GPRD).
Carey IM, Cook DG, De Wilde S, Bremner SA, Richards N, Caine S, Strachan DP, Hilton SR.
BMC Fam Pract. (2003); 4: 14
PMID: 14516473
32.
Does influenza vaccination increase consultations, corticosteroid prescriptions, or exacerbations in subjects with asthma or chronic obstructive pulmonary disease?
Tata LJ, West J, Harrison T, Farrington P, Smith C, Hubbard R.
Thorax. (2003); 58: 835-9
PMID: 14514932
33.
34.
35.
The incidence of sterilisation in the UK .
Rowlands S, Hannaford P.
BJOG. (2003); 110: 819-24
PMID: 14511963
A population based case-control study of cataract and inhaled corticosteroids.
Smeeth L, Boulis M, Hubbard R, Fletcher AE.
Br J Ophthalmol. (2003); 87: 1247-51
PMID: 14507760
Lipid-lowering drugs and the risk of depression and suicidal behavior.
Yang CC, Jick SS, Jick H
Arch Intern Med. (2003);163: 1926-32
PMID: 12963565
36.
37.
38.
39.
40.
41.
The use of inhaled corticosteroids in the United Kingdom and the Netherlands
Van Staa TP, Cooper C, Leufkens HGM, Lammers JW, Suissa S
Resp Med (2003); 97: 578-585
PMID: 12735678
Changes in antipsychotic drug prescribing by general practitioners in the United Kingdom from 1991-
2000: a population-based observational study
Kaye JA, Bradbury BD, Jick H
Br J Clin Pharmacol (2003); 56: 596-575
PMID: 14651732
Cost and effectiveness of brinzolamide versus dorzolamide in current practice: an analysis based on the
UK-GPRD database.
Deschaseaux-Voinet C, Lafuma A, Berdeaux G.
Journal of Medical Economics (2003); 6: 69-78
Comparison of area-based inequality measures and disease morbidity in England, 1994-1998
Hoare J
Health Statistics Quarterly (2003); 18: 18-24
The UK General Practice Research Database experience in COPD pharmacoepidemiology
Soriano J.
Eur Respir J (2003); 22 (Suppl. 43): 17s-22s
Early-life exposure to antibacterials and the subsequent development of hayfever in childhood in the UK: case-control studies using the General Practice Research Database and the Doctors' Independent Network.
Bremner SA, Carey IM, DeWilde S, Richards N, Maier WC, Hilton SR., Strachan DP, Cook DG
Clin Exp Allergy (2003); 33: 1518-1525

42.
43.
PMID: 14616863
Mortality in inflammatory bowel disease: a population-based cohort study.
Card T, Hubbard R, Logan RFA.
Gastroenterology (2003); 125: 1583-1590
PMID: 14724808
Epidemiology and Possible Causes of Autism
Jick H, Kaye JA
Pharmacotherapy (2003); 23: 1524-1530
PMID: 14695031
44.
45.
Prevalence of treated asthma and its management in general practice in England and Wales, 1994-1998
Hoare J, Bruce M, Majeed A
Health Statistics Quarterly (2003); 17: 15-22
Use of alpha-blockers and the risk of hip/femur fractures.
Souverein PC, Van Staa TP, Egberts AC, De la Rosette JJ, Cooper C, Leufkens HG.
J Intern Med. (2003); 254(6):548-54.
PMID: 14641795
46.
Lymphoma rates are low but increased in patients with psoriasis: results from a population-based cohort study in the United Kingdom.
Gelfand JM, Berlin J, Van Voorhees A, Margolis DJ.
Arch Dermatol. (2003); 139): 1425-9.
PMID: 14623702
47. Validity of the General Practice Research Database.
Jick SS, Kaye JA, Vasilakis-Scaramozza C, Garcia Rodriguez LA, Ruigomez A, Meier CR, Schlienger RG,
Black C, Jick H.
Pharmacother. (2003); 23: 686-689
1.
2.
3.
4.
Incidence of chronic atrial fibrillation in general practice and its treatment pattern
Ruigomez A, Johansson S, Wallander MA, Rodriguez LA
J Clin Epidemiol (2002); 55:358-363
PMID: 11927203
Association between acetaminophen or nonsteroidal antiinflammatory drugs and risk of developing ovarian, breast, or colon cancer
Meier CR, Schmitz S, Jick H
Pharmacotherapy (2002); 22: 303-309
PMID: 11898889
Risk of mortality in a cohort of patients newly diagnosed with chronic atrial fibrillation
Ruigomez A, Johansson S, Wallander MA, Garcia Rodriguez LA
BMC Cardiovasc Disord (2002); 2: 5
PMID: 11897013
Hormone replacement therapy and prevention of pressure ulcers and venous leg ulcers
Margolis DJ, Knauss J, Bilker W
Lancet (2002); 359: 675-677
PMID: 11879867
Incidence and natural history of Paget's disease of bone in England and Wales van Staa TP, Selby P, Leufkens HG, Lyles K, Sprafka JM, Cooper C

9.
10.
5. J Bone Miner Res (2002); 17: 465-471
PMID: 11878305
Treatment patterns among newly diagnosed heart failure patients in general practice
Johansson S, Wallander MA, Ruigomez A, Garcia R
6. Eur J Clin Pharmacol (2002); 57: 813-817
Venous leg ulcer: incidence and prevalence in the elderly
Margolis DJ, Bilker W, Santanna J, Baumgarten M
J Am Acad Dermatol (2002); 46: 381-386
7. PMID: 11862173
8.
Levothyroxine treatment and occurrence of fracture of the hip
Sheppard MC, Holder R, Franklyn JA
Arch Intern Med (2002); 162: 338-343
PMID: 11822927
Statins and the risk of idiopathic venous thromboembolism
Yang CC, Jick SS, Jick H
Br J Clin Pharmacol (2002);53:101-105
Early exposure to infections and antibiotics and the incidence of allergic disease: a birth cohort study with the West Midlands General Practice Research Database
McKeever TM, Lewis SA, Smith C, Collins J, Heatlie H, Frischer M, Hubbard R
J Allergy Clin Immunol (2002); 109: 43-50
PMID: 11799364
Antiepileptic drugs: coprescription of proconvulsant drugs and oral contraceptives: a national study of
11.
12. antiepileptic drug prescribing practice
Shorvon SD, Tallis RC, Wallace HK
J Neurol Neurosurg Psychiatry (2002); 72: 114-115
PMID: 11784837
The epidemiology and treatment of Bell's palsy in the UK
Rowlands S, Hooper R, Hughes R, Burney P
Eur J Neurol (2002);9:63-67
PMID: 11784378
13.
14.
15.
16.
Prescribing patterns in premenstrual syndrome
Wyatt KM, Dimmock PW, Frischer M, Jones PW, O'Brien SP
BMC Womens Health (2002); 2: 4
PMID: 12086594
Itraconazole and fluconazole and certain rare, serious adverse events
Bradbury BD, Jick SS
Pharmacotherapy (2002); 22: 697-700
PMID: 12066960
The Incidence and Prevalence of Pressure Ulcers among Elderly Patients in General Medical Practice
Margolis DJ, Bilker W, Knauss J, Baumgarten M, Strom BL
Ann Epidemiol (2002); 12: 321-325
PMID: 12062919
Validity and completeness of the General Practice Research Database for studies of inflammatory bowel disease
Lewis JD, Brensinger C, Bilker WB, Strom BL
Pharmacoepidemiol Drug Saf (2002); 11: 211-218
PMID: 12051120
The impact of coexisting connective tissue disease on survival in patients with fibrosing alveolitis

17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
Hubbard R, Venn A
Rheumatology (2002); 4: 676-679
PMID: 12048295
Clinical risk factors for venous thromboembolus in users of the combined oral contraceptive pill
Black C, Kaye JA, Jick H
Br J Clin Pharmacol ( 2002); 53: 637-640
PMID: 12047488
The general fertility rate in women with psychotic disorders
Howard LM, Kumar C, Leese M, Thornicroft G
Am J Psychiatry (2002); 159: 991-997
PMID: 12042188
Peptic ulceration in general practice in England and Wales 1994-98: period prevalence and drug management
Kang JY, Tinto A, Higham J, Majeed A
Aliment Pharmacol Ther (2002); 16: 1067-1074
PMID: 12030947
Lower risk of thromboembolic cardiovascular events with naproxen among patients with rheumatoid arthritis
Watson DJ, Rhodes T, Cai B, Guess HA
Arch Intern Med (2002); 162: 1105-1110
PMID: 12020179
Risk of clinical blood dyscrasia in a cohort of antibiotic users
Huerta C, Garcia Rodriguez LA
Pharmacotherapy (2002); 22: 630-636
PMID: 12013362
Drug or symptom-induced depression in men treated with alpha 1-blockers for benign prostatic hyperplasia? A nested case-control study
Clifford GM, Farmer RD
Pharmacoepidemiol Drug Saf (2002); 11: 55-61
PMID: 11998552
Risk of irritable bowel syndrome among asthma patients
Huerta C, Garcia Rodriguez LA, Wallander MA, Johansson S
Pharmacoepidemiol Drug Saf (2002); 11: 31-35
PMID: 11998549
Mode of delivery and risk of developing allergic disease
McKeever TM, Lewis SA, Smith C, Hubbard R
J Allergy Clin Immunol (2002); 109: 800-802
PMID: 11994703
Statin use, hyperlipidaemia, and the risk of breast cancer
Kaye JA, Meier CR, Walker AM, Jick H
Br J Cancer (2002); 86: 1436-1439
PMID: 11986777
Geriatric drug therapy and healthcare utilization in the United Kingdom
Kennerfalk A, Ruigomez A, Wallander MA, Wilhelmsen L, Johansson S
Ann Pharmacother (2002); 36: 797-803
PMID: 11978154
The effects of air pollution on general practitioner consultations for upper respiratory diseases in London
Hajat S, Anderson HR, Atkinson RW, Haines A
Occup Environ Med (2002); 59: 294-299

29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
PMID: 11983844
Asociations of cold temperatures with GP consultations for respiratory and cardiovascular disease amongst the elderly in London
Hajat S, Haines A
Int J Epidemiol (2002); 31: 825-830
PMID: 12177030
Comparison of speciality referral rates in the United kingdom and the United states: retrospective cohort analysis
Forrest CB, Majeed A, Weiner JP, Bindman AB
Br Med J (2002); 325: 370-371
PMID: 12183310
Incident diabetes associated with antipsychotic use in the United Kingdom general practice research database
Kornegay CJ, Vasilakis-Scaramozza C, Jick H
J Clin Psychiatry (2002); 63: 758-762
PMID: 12363114
Use of nonsteroidal anti-inflammatory drugs and the risk of first-time acute myocardial infarction
Schlienger RG, Jick H, Meier CR
Br J Clin Pharmacol (2002); 54: 327-332
PMID: 12236854
Association between migraine and asthma: matched case-control study
Davey G, Sedgwick P, Maier W, Visick G, Strachan DP, Anderson HR
Br J Gen Pract (2002); 52: 723-727
PMID: 12236275
The importance of prenatal exposures on the development of allergic disease: a birth cohort study using the west midlands general practice database
McKeever TM, Lewis SA, Smith C, Hubbard R
Am J Respir Crit Care Med (2002); 166: 827-832
PMID: 12231492
Risk of acute liver injury in patients with diabetes
Huerta C, Zhao SZ, Garcia Rodriguez LA
Pharmacotherapy (2002); 22:1091-1096
PMID: 12222543
Relation of childhood gastrointestinal disorders to autism: nested case-control study using data from the
UK General Practice Research Database
Black C, Kaye JA, Jick H
Br Med J (2002); 325: 419-421
PMID: 12193358
Does a fracture at one site predict later fractures at other sites? A British cohort study van Staa TP, Leufkens HG, Cooper C
Osteoporos Int (2002); 13: 624-629
PMID: 12181620
Consultation rates from the general practice research database
Rowlands S, Moser K
Br J Gen Pract (2002); 52: 658-660
PMID: 12171226
Respiratory medications and risk of asthma death
Lanes SF, Garcia Rodriguez LA, Huerta C
Thorax (2002); 57: 683-686

40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
PMID: 12149527
Can the General Practice Research Database be used to monitor the heath of babies and their mothers?
Macfarlane A, Hockley C, McCandlish R, McNiece R
Health Statistics Quarterly (2002); 13: 5-15
Age and sex-specific antibiotic prescribing patterns in general practice in England and Wales, 1994 to
1998
Wrigley T, Tinto A, Majeed A
Health Statistics Quarterly (2002); 14: 14-20
Epilepsy prevalence and prescribing patterns in England and Wales
Purcell B, Gaitatzis A, Sander JW, Majeed A
Health Statistics Quarterly (2002); 15: 23-30
Prevalence of diagnosed diabetes in general practice in England and Wales, 1994 to 1998
Newnham A, Ryan R, Khunti K, Majeed A
Health Statistics Quarterly (2002); 14: 5-13
Etiology and frequency of rhabdomyolysis
Black C, Jick H
Pharmacotherapy (2002); 22: 1524-1526
PMID: 12495162
Accruing large numbers of patients in primary care trials by retrospective recruitment methods
McCarney R, Fisher P, van Haselen R
Complement Ther Med (2002); 10: 63-88
PMID: 12481953
Risk of serious skin disorders among users of oral antifungals: a population-based study
Castellsague J, Garcia-Rodriguez LA, Duque A, Perez S
BMC Dermatol (2002) 28; 2: 14
PMID: 12456265
Association between body mass index and liver disorders: an epidemiological study
Meier CR, Krahenbuhl S, Schlienger RG, Jick H
J Hepatol (2002); 37: 741-747
PMID: 12445413
An assessment of the independent effects of olanzapine and risperidone exposure on the risk of hyperlipidemia in schizophrenic patients
Koro CE, Fedder DO, L'Italien GJ, Weiss S, Magder LS, Kreyenbuhl J, Revicki D, Buchanan RW
Arch Gen Psychiatry (2002); 59: 1021-1026
PMID: 12418935
Survival in COPD patients after regular use of fluticasone propionate and salmeterol in general practice
Soriano JB, Vestbo J, Pride NB, Kiri V, Maden C, Maier WC
Eur Respir J (2002); 20: 819-825
PMID: 12412670
Inhaled corticosteroids and hip fracture: a population-based case-control study
Hubbard RB, Smith CJ, Smeeth L, Harrison TW, Tattersfield AE
Am J Respir Crit Care Med (2002) 15; 166: 1563-1566
PMID: 12406825
Utility of medical and drug history in fracture risk prediction among men and women van Staa TP, Leufkens HG, Cooper C
Bone (2002); 31: 508-514
PMID: 12398948

1.
52.
53.
54.
55.
56.
Differences in the use of health services among people with and without epilepsy in the United Kingdom: socio-economic and disease-specific determinants.
Gaitatzis A, Purcell B, Carroll K, Sander JWAS, Majeed A
Epilepsy Res (2002); 50: 233-241
PMID: 12200214
Trends in the treatment of osteoporosis and types of drug treatments prescribed in general practice in
England and Wales, 1994 to 1998.
Bailey K, Ellis C, Majeed A.
Health Statistics Quarterly (2002); 16: 5-13
Prevalence of treated hypertension in general practice in England and Wales, 1994 to 1998.
Ryan R, Majeed A.
Health Statistics Quarterly (2002); 16: 14-18
Population need for coronary revascularisation: are national targets credible?
Martin RM, Hemingway H, Gunnell D, Karsch KR, Baumbach A, Frankel S
Heart (2002); 88: 627-633
PMID: 12433896
Assessment of independent effect of olanzapine and risperidone on risk of diabetes among patients with schizophrenia: population based nested case-control study
Koro CE, Fedder DO, L’Italien GJ, Weiss SS, Magder LS, Kreyenbuhl J, Revicki DA, Buchanan RW
Br Med J. (2002); 325: 243-245
PMID: 12153919
2.
3.
4.
5.
Postmenopausal estrogen replacement therapy and the risk of Alzheimer’s disease
Seshadri S, Zornberg GL, Derby LE, Myers MW, Jick H, Drachman DA
Arch Neurol (2001); 58(3): 435-440
PMID: 11255447
Incidence of newly diagnosed heart failure in UK general practice
Johansson S, Wallander M, Ruigomez A, Garcia Rodriguez LA
Eur J Heart Fail (2001); 3(2): 225-231
PMID: 11246061
A case-control study of autism and mumps-measles-rubella vaccination using the general practice research database: design and methodology
Smeeth L, Hall AJ, Fombonne E, Rodrigues LC, Huang X, Smith PG
BMC Public Health (2001); 1(1): 2
PMID: 11231881
Risk of upper gastrointestinal bleeding and perforation associated with low-dose aspirin as plain and enteric-coated formulations de Abajo FJ, Garcia Rodriguez LA
BMC Clin Pharmacol (2001); 1(1): 1
PMID: 11228592
Mumps, measles, and rubella vaccine and the incidence of autism recorded by general practitioners: a time trend analysis
Kaye JA, del Mar Melero-Montes M, Jick H
Br Med J (2001); 322: 460-463
PMID: 11222420
Epidemiologic assessment of the safety of conventional nonsteroidal anti-inflammatory drugs
Hernandez-Diaz S, Garcia-Rodriguez LA

9.
6. Am J Med (2001); 110 (3 Suppl 1): 20-27
PMID: 11173046
Reduced risk of colorectal cancer among long-term users of aspirin and nonaspirin nonsteroidal
7. antiinflammatory drugs
Garcia-Rodriguez LA, Huerta-Alvarez C
Epidemiology (2001); 12: 88-93
PMID: 11138826
8.
Public health impact of adverse bone effects of oral corticosteroids
Van Staa TP., Abenhaim L., Cooper C., Zhang B., Leufkens HG
Br J Clin Pharmacol (2001); 6:601-607
PMID: 11422020
Inequalities in treated heart disease and mental illness in England and Wales, 1994-1998
Moser K
Br J Gen Pract (2001); 467:438-444
PMID: 11407047
Steroids and risk of upper gastrointestinal complications
Hernandez-Diaz S, Rodriguez LA
10.
11.
Am J Epidemiol (2001); 153:1089-1093
PMID: 11390328
Mumps, measles, and rubella vaccine and the incidence of autism recorded by general practitioners: a time-trend analysis
Kaye JA, Maria Del Mar MM, Jick H
West J Med (2001); 174:387-390
PMID: 11222420
12.
13.
14.
Renal failure in patients with neurogenic lower urinary tract dysfunction
Lawrenson R, Wyndaele JJ, Vlachonikolis I, Farmer C, Glickman S
Neuroepidemiology (2001); 20:138-143
PMID: 11359083
Preferential prescribing of type of combined oral contraceptive pill by general practitioners to teenagers with acne
Rowlands S, Devalia H, Lawrenson R
Eur J Contracept Reprod Health Care (2001); 6:9-13
PMID: 11334479
Trends in antibiotic prescribing and associated indications in primary care from 1993 to 1997
Frischer M, Heatlie H, Norwood J, Bashford J, Millson D, Chapman S
J Public Health Med (2001); 23:69-73
PMID: 11315698
15.
16.
Use of statins and risk of fractures van Staa TP, Wegman S, de Vries F, Leufkens B, Cooper C
JAMA. 2001 Apr 11;285(14):1850-5
PMID: 11308398
Use of inhaled corticosteroids and risk of fractures van Staa TP, Leufkens HG, Cooper C
J Bone Miner Res (2001); 16:581-588
PMID: 11277277
Lower urinary tract symptoms suggestive of benign prostatic obstruction - triumph: the role of general practice databases

17. Logie JW, Clifford GM, Farmer RD, Meesen BP
Eur Urol (2001); 39 Suppl 3:42-47
PMID: 11275742
18.
Lower urinary tract symptoms suggestive of benign prostatic obstruction - triumph: design and implementation
Chapple CR
Eur Urol (2001); 39 Suppl 3:31-36
PMID: 11275740
19.
Are users of lipid-lowering drugs at increased risk of peripheral neuropathy?
Gaist D, Alberto L, Rodriguez G, Huerta C, Hallas J, Sindrup SH
Eur J Clin Pharmacol (2001); 56:931-933
PMID: 11800044
Diagnosis and Initial Management of Stroke and Transient Ischemic Attack Across UK Health Regions
20.
21.
From 1992 to 1996 : Experience of a National Primary Care Database
Gibbs RG, Newson R, Lawrenson R, Greenhalgh RM, Davies AH
Stroke (2001): 32: 1085-1090
PMID: 11340214
Trends in the prevalence and management of atrial fibrillation in general practice in England and Wales,
1994-1998: analysis of data from the general practice research database
Majeed A, Moser K, Carroll K
Heart (2001); 86: 284-288
22.
23.
PMID: 11514479
The risk of liver damage associated with minocycline: a comparative study
Seaman HE, Lawrenson RA, Williams TJ, MacRae KD, Farmer RD
J Clin Pharmacol ( 2001); 4: 852-860
PMID: 11504273
The risk of obstructive airways disease in a glaucoma population
Huerta C, Garcia Rodriguez LA, Moller CS, Arellano FM
Pharmacoepidemiol Drug Saf (2001); 10: 157-163
PMID: 11499855
24.
25.
26.
27.
28.
Use of selective serotonin reuptake inhibitors and risk of developing first-time acute myocardial infarction
Meier CR, Schlienger RG, Jick H
Br J Clin Pharmacol. (2001); 52:179-184
PMID: 11488775
Patterns of prescribing of nutritional supplements in the United Kingdom
Gale CR, Edington J, Coles SJ, Martyn CN
Clin Nutr (2001); 20: 333-337
PMID: 11478831
Consultations and referrals for dyspepsia in general practice-a one year database survey van Bommel MJ, Numans ME, de Wit NJ, Stalman WA
Postgrad Med J (2001); 77: 514-518
PMID: 11470932
Otitis externa in UK general practice: a survey using the UK General Practice Research Database
Rowlands S, Devalia H, Smith C, Hubbard R, Dean A
Br J Gen Pract (2001); 51: 533-538
PMID: 11462312
Public health impact of adverse bone effects of oral corticosteroids van Staa TP, Abenhaim L, Cooper C, Zhang B, Leufkens HG
Br J Clin Pharmacol (2001); 51: 601-607

29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
PMID: 11422020
Incidence of ocular melanoma in the general population and in glaucoma patients
Huerta C, Garcia Rodriguez LA
J Epidemiol Community Health (2001); 55: 338-339
PMID: 11297655
Time trends in GP outpatient referrals
Hodgson C, Ellis C
Health Statistics Quarterly (2001); 10:14-19
Antibiotic failure in the treatment of urinary tract infections in young women
Lawrenson RA, Logie JW
J Antimicrob Chemother (2001); 48: 895-901
PMID: 11733475
Epidemiology of fractures in England and Wales van Staa TP, Dennison EM, Leufkens HG, Cooper C
Bone (2001); 29: 517-522
PMID: 11728921
The excess cost of acute exacerbations of chronic bronchitis in patients aged 45 and older in England and
Wales
McGuire A, Irwin DE, Fenn P, Gray A, Anderson P, Lovering A, MacGowan A.
Value Health (2001); 4: 370-375
PMID: 11705127
Acetaminophen and the risk of renal and bladder cancer in the general practice research database
Kaye JA, Wald Myers M, Jick H
Epidemiology (2001); 12: 690-694
PMID: 11679798
Live attenuated polio vaccine and the risk of intussusception.
Jick H, Vasilakis-Scaramozza C, Jick SS
Br J Clin Pharmacol (2001); 52: 451-453
PMID: 11678790
Inflammatory Bowel Disease is not associated with an increased risk of lymphoma
Lewis JD, Bilker WB, Brensinger C, Deren JJ, Vaughn DJ, Strom BL
Gastroenterology (2001); 121:1080-1087
PMID: 11740233
Risk of cataract in patients treated with statins
Schlienger RG, Haefeli WE, Jick H, Meier CR
Arch Intern Med (2001);161: 2021-2026
PMID: 11525705
Siblings, multiple births, and the incidence of allergic disease: a birth cohort study using the West
Midlands general practice research database
McKeever TM, Lewis SA, Smith C, Collins J, Heatlie H, Frischer M, Hubbard R
Thorax (2001); 56: 758-762
PMID: 11562513
Prevalence of ischaemic heart disease and its management with statins and aspirin in general practice in
England and Wales, 1994 and 1998
Ryan R, Majeed A
Health Statistic Quartely (2001); 12, 34-39
Prevalence of comorbid mental illness and drug use recorded in general practice: preliminary findings from the General Practice Research Database

40. Frischer M, Akram G
Drugs: education, prevention and policy (2001); 8: 276-280
Does oral polio vaccine cause intussusception in infants? Evidence from a sequence of three self-controlled
41. cases series studies in the United Kingdom
Andrews N, Miller E, Waight P, Farrington P, Crowcroft N, Stowe J, Taylor B
Eur J Epidemiol (2001); 17: 701-706
PMID: 12086086
42.
43.
Association between air pollution and daily consultations with general practitioners for allergic rhinitis in
London, United Kingdom.
Hajat S, Haines A, Atkinson RW, Bremner SA, Anderson HR, Emberlin J
J Epidemiol (2001);153:704-714
PMID: 11282799
Use of the combined oral contraceptive pill by under 16s
Rowlands S, Devalia H, Lawrenson R
J Fam Plann Reprod Health Care (2001); 27: 17-19
PMID: 12457541
44.
45.
46.
The risk of cataract among users of inhaled steroids
Jick SS, Wasilakis-Scaramozza C, Maier WC.
Epidemiology (2001); 12: 229-234
PMID: 11246585
Prevalence and management of heart failure in England and Wales, 1994-98
Ellis C, Gnani S, Majeed A
Health Statistics Quarterly (2001); 11: 17-24
Lipid-lowering drugs and risk of myopathy: a population-based follow-up study
Gaist D, Garcia Rodriguez LA, Huerta C, Hallas J, Sindrup SH
Epidemiol (2001); 12: 565-569
PMID: 11505177
47.
48.
49.
50.
The risk of upper gastrointestinal complications associated with nonsteroidal anti-inflammatory drugs, glucocorticoids, acetaminophen and combination of these agents
Garcia Rodriguez LA, Hernandez-Diaz S
Arthritis Research (2001); 3: 98-101
PMID: 11178116
Relative risk of upper gastrointestinal complications among users of acetaminophen and nonsteroidal antiinflammatory drugs
Garcia Rodriguez LA, Hernandez Dias S
Epidemiol (2001); 12: 570-576
PMID: 11505178
Gender and drug treatment as determinants of mortality in a cohort of heart failure patients
Ruigomez A, Johannson S, Wallander M-A, Garcia Rodriguez LA
Eur J Epidemiol (2001); 17: 329-335
PMID: 11767958
Risk of venous thromboembolism with cyproterone or levonorgestrel contraceptives
Vasilakis-Scaramozza C, Jick H
Lancet (2001); 358: 1427-1429
PMID: 11705493

9.
1.
2.
3.
4.
5.
6.
7.
8.
10.
11.
Angiotensin-converting enzyme inhibitors, calcium channel blockers and breast cancer
Meier CR, Derby LE, Jick SS, Jick H
Arch Int Med (2000); 160: 349-353
PMID: 10668837
The risk of acute pancreatitis associated with acid-suppressing drugs
Eland IA, Huerta-Alvarez C, Stricker BHCH, Garcia Rodriguez LA
Br J Clin Pharmacol (2000); 49: 473-478
PMID: 10792205
Antihypertensive drugs and the risk of idiopathic aplastic anemia
Myers MW, Vasilakis C, Kaufman MR, Jick H
Br J Clin Pharmacol (2000); 49: 604-608
PMID: 10848725
Intracranial hemorrhage and use of selective serotonin reputake inhibitors
De Abajo FJ, Jick H, Derby LE, Jick SS, Schmitz SM
Br J Clin Pharmacol (2000); 50: 43-47
PMID: 10886117
A comparison of the risks of venous thromboembolic disease in association with different combined oral contraceptives
Farmer RDT, Lawrenson RA, Todd J-C, Williams TJ, MacRae KD, Tyrer F, Leydon GM
Br J Clin Pharmacol (2000); 49: 580-590
PMID: 10848722
Validation of the diagnosis of venous thromboembolism in general practice database studies
Lawrenson RA, Todd J-C, Leydon GM, Williams TJ, Farmer RDT
Br J Clin Pharmacol (2000); 49: 591-596
PMID: 10848723
Incidence of venous thromboembolism in users of combined oral contraceptives. Methods for identifying cases and estimating person time at risk must be detailed.
Jick H.
Br Med J (2000); 320(7226): 57
PMID: 10617543
Risk of suicide among users of calcium channel blockers: population based, nested case-control study
Gasse C, Derby LE, Vasilakis C, Jick H
Br Med J (2000); 320: 1251
PMID: 10797037
Effect of 1995 pill scare on rates of venous thromboembolism among women taking combined oral contraceptives: analysis of General Practice Research Database
Farmer RDT, Williams TJ, Simpson EL, Nightingale AL
Br Med J (2000); 321: 477-479
PMID: 10948026
Reduced incidence of colorectal adenoma among long-term users of nonsteroidal antiinflammatory drugs: a pooled analysis of published studies and a new population based study
Garcia Rodriguez LA, Huerta-Alvarez C
Epidemiology (2000); 11: 376-381
PMID: 10874542
Differential effects of aspirin and non-aspirin nonsteroidal antiinflammatory drugs in the primary prevention of myocardial infarction in postmenopausal women
Garcia Rodriguez LA, Varas C, Patrono C
Epidemiology (2000); 11: 382-387
PMID: 10874543

12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
Risk of cataract among users of intranasal corticosteroids
Derby LE, Maier WC
J Aller Clin Immunol (2000); 105: 912-916
PMID: 10808171
Use of oral corticosteroids and risk of fractures van Staa TP, Leufkens H, Abenhaim L, Zhang B, Cooper C
J Bone Miner Res (2000); 15(6): 993-1000
PMID: 10841167
Oral corticosteroids and fracture risk: relationship to daily and cumulative doses. van Staa TP, Leufkens HG, Abenhaim L, Zhang B, Cooper C.
Rheumatology (Oxford). 2000; 39(12):1383-9.
PMID: 11136882
Overall mortality among patients surviving an episode of peptic ulcer bleeding
Ruigomez A, Garcia Rodriguez LA, Hasselgren G, Johansson S, Wallander MA
J Epidemiol Commun Health (2000); 54: 130-133
PMID: 10715746
HMG-CoA reductase inhibitors and the risk of fractures
Meier CR, Schlienger RG, Kraenzlin ME, Schlegel B, Jick H
JAMA (2000); 283: 3205-3210
PMID: 10866867
The risk of gastrointestinal bleed, myocardial infarction, and newly diagnosed hypertension in users of meloxicam, diclofenac, naproxen and piroxicam
Jick SS
Pharmacotherapy (2000); 20: 741-744
PMID: 10907963
Effect of anti-inflammatory drugs on overall risk of common cancer: case-control study in general practice research database
Langman MJS, Cheng KK, Gilman EA, Lancashire R J
Br Med J (2000); 320: 1642-1646
PMID:10856067
Exposure to antidepressants and the risk of cryptogenic fibrosing alveolitis: a case-control study
Hubbard R, Venn A, Britton J
Eur Respir J (2000); 16: 409-413
PMID: 11028652
Medical events and resources utilisation in cancer-pain patients treated with strong opioids: An analysis of the UK general practice research database
Tooley JH, Cookson RF, Jones M, Nuyts GD
J Outcomes Res (2000); 4:1-14
Adult height and cryptogenic fibrosing alveolitis: a case-control study using the UK general practice research database
Hubbard R, Venn A
Thorax (2000); 55: 864-866
PMID: 10992540
Antibiotics in the prevention and treatment of coronary heart disease.
Meier CR
J Infect Dis (2000); 181: S558-S562
PMID: 10839758
Recent trends in physician diagnosed COPD in women and men in the UK

23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
Soriano JB, Maier WC, Egger P. Visick G, Thakrar B, Sykes J, Pride NB
Thorax. (2000);55: 789-794
PMID: 10950900
Population-based study on incidence, risk factors, clinical complications and drug utilisation associated with influenza in the United Kingdom
Meier CR, Napalkov PN, Wegmueller Y, Jefferson T, Jick H
Eur J Clin Microbiol Infect Dis (2000); 19: 834-42
PMID: 11152308
Isotretinoin use and risk of depression, psychotic symptoms, suicide and attempted suicide
Jick SS, Kremers HM, Vasilakis-Scaramozza C
Arch Dermatol (2000); 136:1231-1236
PMID: 11030769
Incidence of first-time idiopathic seizures in users of tramadol
Gasse C, Derby LE, Vasilakis-Scaramozza C, Jick H
Pharmacotherapy (2000); 20: 629-634
PMID: 10853617
The incidence of breast cancer in the general practice research database compared with national cancer registration data
Kaye JA, Derby LE, Melero-Montes MM, Quinn M, Jick H
Br J Cancer (2000);83(11):1556-1558
PMID: 11076668
Antipsychotic drug use and risk of first-time idiopathic venous thromboembolism: a case-control study
Zornberg GL, Jick H
Lancet (2000); 356:1219-1223
PMID: 11072939
Statins and the risk of dementia
Jick H, Zornberg GL, Jick SS, Seshadri S, Drachman, DA
Lancet (2000); 356: 1627-1631
PMID: 11089820
Risk of venous thromboembolism among users of third generation oral contraceptives compared with users of oral contraceptives with levonorgestrel before and after 1995: cohort and case-control analysis
Jick H, Kaye JA, Vasilakis-Scaramozza C, Jick SS
Br Med J (2000); 321:1190-1195
PMID: 11073511
Use of oral corticosteroids and risk of fractures .
Van Staa TP, Leufkens HG, Abenhaim L, Zhang B, Cooper C.
J Bone Miner Res. 2000 Jun;15(6):993-1000.
PMID: 10841167
A UK general practice database study of prevalence and mortality of people with neural tube defects
Lawrenson R, Wyndaele JJ, Viachonikolis I, Farmer C, Glickman S
Clin Rehabil (2000); 14(6): 627-630
PMID: 11128738
How do symptoms indicative of BPH progress in real life practice? The UK experience
Clifford GM, Logie J, Farmer RD
Eur Urol (2000); 38(Suppl 1): 48-53
PMID: 11111208
Venous thromboembolism and combined oral contraceptives: does the type of progestogen make a difference?
Lawrenson R, Farmer R

35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
Contraception (2000); 62(Suppl 2): S21-S28
PMID: 11102599
A comparison of trends in problematic drug misuse from two reporting systems
Frischer M, Heatlie H, Milison D, Lowdell J, Hickman M, Chapman S, Bashford J, Norwood J
J Pub Health Med (2000); 22: 362-367
PMID: 11077911
Age, sex and practice variations in the use of statins in general practice in England and Wales
Majeed A, Moser K, Maxwell R
J Pub Health Med (2000); 22: 275-279
PMID: 11077897
Use of nonsteroidal anti-inflammatory drugs and risk of fractures van Staa TP, Leufkens HG, Cooper C
Bone (2000); 27:563-568
PMID: 11033453
Repeated use of hormonal emergency contraception by younger women in the UK
Rowlands S, Devalia H, Lawrenson R, Logie J, Ineichen B
Br J Fam Plann (2000); 26:138-143
PMID: 10920289
Hormone replacement therapy and incidence of acute myocardial infarction: A population-based nested case-control study
Varas-Lorenzo C, Garcia Rodriguez LA, Pérez-Gutthann S, Duque-Oliart A
Circulation (2000) 101: 2572-2578
PMID: 10840007
Are schizophrenia or antipsychotic drugs a risk factor for cataracts?
Ruigomez A, Garcia Rodriguez LA, Dev VJ, Arellano F, Raniwala J
Epidemiology (2000); 11: 620-623
PMID: 11055620
Epidemiology of pneumothorax in England
Gupta D, Hansell A, Nichols T, Duong T, Ayres JG, Strachan D
Thorax (2000); 55:666-671
PMID: 10899243
Multiple sclerosis and antecedent infections: a case-control study
Marrie RA, Wolfson C, Sturkenboom MC, Gout O, Heinzlef O, Roullet E, Abenhaim L
Neurology (2000); 54: 2307-2310
PMID: 10881258
Lung cancer and cryptogenic fibrosing alveolitis. A population-based cohort study
Hubbard R, Venn A, Lewis S, Britton J
Am J Respir Crit Care Med (2000); 161:5-8
PMID: 10619790
Use of oral corticosteroids in the United Kingdom van Staa TP, Leufkens HG, Abenhaim L, Begaud B, Zhang B, Cooper C
QJ Med (2000); 93:105-111
PMID: 10700481
Detection of colorectal tumor and inflammatory bowel disease during follow-up of patients with initial diagnosis of irritable bowel syndrome
Garcia Rodriguez LA, Ruigomez A, Wallander MA, Johansson S, Olbe I
Scandinav J Gastroenterol (2000); 35:306-311
PMID: 10766326

46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
56.
Overall mortality among patients surviving an episode of peptic ulcer bleeding
Ruigomez A, Garcia Rodriguez LA, Hasselgren G, Johansson S, Wallander MA
J Epidemiol Commun Health (2000); 54:130-133
PMID: 10715746
How do symptoms indicative of BPH progress in real life practice? The UK Experience
Clifford GM, Logie J, Farmer RD
Eur Urol (2000); 38 Suppl S1: 48-53
PMID: 11111208
The effects of age, body mass index, smoking and general health on the risk of venous thromboembolism in users of combined oral contraceptives
Nightingale AL, Lawrenson RA, Simpson EL, Williams TJ, MacRae KD, Farmer RD
Eur J Contracept Reprod Health Care (2000); 5:265-274
PMID: 11245554
Ratio of inhaled corticosteroid to bronchodilator and hospital referral for asthma: a patient level analysis using the General Practice Research Database
Frischer M, Heatlie H, Chapman S, Bashford J, Norwood J, Millson D
Curr Med Res Opin (2000); 16; 8-13
PMID: 16422029
Defining the spectrum of appropriate prescribing: implications for effective medicines management
Frischer M, Heatlie H, Chapman S, Millson D
Int J Pharm Med (2000); 14: 17-21
Are triptans with enhanced lipophilicity used for the acute treatment of migraine associated with increasing consulting rates for depressive illness?
Millson D, Frischer M, Croft P, Goadsby P
Cephalalgia (2000); 20: 732-737
PMID: 11167903
Patterns of prescription of PC4 by general practitioners in England and Wales.
Ineichen B, Logie J, Rowlands S, Lawrenson R
Eur J Contracept Reprod Health Care (2000); 5: 241-247
PMID: 11245551
Hyperemesis gravidarum and the sex of the baby
Melero Montes MM, Jick H
Epidemiology (2000); 12: 123-4
PMID: 11176253
Baseline risk of gastro-intestinal disorders among new users of meloxicam, ibuprofen, diclofenac, naproxen and indomethacin
Lanes SF, Garcia Rodriguez LA, Hwang E
Pharmacoepidemiol & Drug Safety (2000); 9: 113-117
PMID: 19025810
Morbidity and treatment data from general practice 1998 (England and Wales)
Office for National Statistics
Health Statistics Quarterly(2000); 8: 81-86
The use of a large pharmacoepidemiological database to study exposure to oral corticosteroids and risk of fractures: validation of study population and results van Staa TP, Abenhaim L, Cooper C, Zhang B, Leufkens HGM
Pharmacoepidemiol & Drug Safety (2000); 9: 359-366

9.
1.
2.
3.
4.
5.
6.
7.
8.
10.
11.
Prevalence of asthma in general practice
Office for National Statistics
Asthma J(1999); 4: 79-80
Health of older people: disease prevalence, prescription and referral rates, England and Wales 1996
Carter M, Moser K, Kelly S
Health Statistics Quarterly (1999); 4: 9-15
Association between selective serotonin reuptake inhibitors and upper gastrointestinal bleeding: population based case-control study
De Abajo FJ, Garcia Rodriguez LA, Montero D
Br Med J (1999); 319: 1106-1109
PMID: 10531103
Use of dexfenfluramine, fenfluramine and phentermine and the risk of stroke
Derby LE, Myers MW, Jick H
Br J Clin Pharmacol (1999); 47: 565-569
PMID: 10336582
Switching between Metered Dose Inhalers (MDIs) and Dry Powder Inhalers (DPIs) in airways disease: an analysis of age-specific rates using the General Practice Research Database
Frischer M, Heatlie H, Chapman S, Bashford J, Norwood J
J Appl Ther Res (1999); 2: 253-259
Should the corticosteroid to bronchodilator ratio be promoted as a quality prescribing marker?
Frischer M, Heatlie H, Chapman S, Norwood J, Bashford J, Milison D
Public Health (1999); 113: 247-250
PMID: 10557120
Increased risk of irritable bowel syndrome after bacterial gastroenteritis: cohort study
Garcia Rodriguez LA, Ruigomez A
Br Med J (1999); 318: 565-566
Secondary prevention of upper gastrointestinal bleeding associated with maintenance acid-suppressing treatment in patients with peptic ulcer bleed
Garcia Rodriguez LA, Ruigomez A
Epidemiology(1999); 10: 228-232
PMID: 10230829
Association of air pollution with daily GP consultations for asthma and other lower respiratory conditions in London
Hajat S, Goubert SA, Haines A, Atkinson RW, Anderson HR
Thorax (1999); 54: 597-605
PMID: 10377204
Use of the General Practice Research Database (GPRD) for respiratory epidemiology: a comparison with the 4th Morbidity survey in general practice (MSGP4)
Hansel A, Hollowell J, Nichols T, McNiece R, Strachan D
Thorax (1999); 54: 413-419
PMID: 10212105
Pregnancy outcomes after maternal exposure to fluconazole
Jick SS
Pharmacotherapy (1999); 19: 221-222
PMID: 10030772

12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
Risk of idiopathic cerebral haemorrhage in women on oral contraceptives with differing progestagen components (research letter)
Jick SS, Myers MW, Jick H
Lancet (1999); 354: 302-303
PMID: 10440310
Hormone Replacement Therapy: patterns of use studied through British general practice computerized records
Lawrence M, Jones L, Lancaster T, Daly E
Family Practice (1999); 16: 335-342
PMID: 10493702
Age- and sex-specific antibiotic prescribing patterns in general practice in England and Wales in 1996
Majeed A, Moser K
Br J Gen Pract (1999); 49: 735-736
PMID: 10756619
Prescribing for patients with asthma by general practitioners in England and Wales 1994-1996
Majeed A, Moser K
Health Statistics Quarterly (1999); 1: 16-20
Prevalence and management of heart failure in general practice in England and Wales 1994-96
Majeed A, Moser K
Health Statistics Quarterly (1999); 4: 5-8
Antibiotics and risk of subsequent first-time acute myocardial infarction
Meier CR, Derby LE, Jick SS, Vasilakis C, Jick H
JAMA (1999); 281: 427-431
PMID: 9952202
Prevalence of treated chronic diseases in general practice in England and Wales - trends over time and variations by the ONS area classification
Moser K, Majeed A
Health Statistics Quarterly (1999); 2: 25-32
Low-dose diclofenac, naproxen and ibuprofen cohort study
Perez Gutthann S, Garcia Rodriguez LA, Duque Oliart A, Varas-Lorenzo C
Pharmacotherapy (1999); 19(7): 854-859
PMID: 10417034
Use of cimetidine, omeprazole and ranitidine in pregnant women and pregnancy outcomes
Ruigomez A, Garcia Rodriguez LA, Cattaruzzi C, Troncon MG, Agostinis L, Wallander MA, Johansson S
Am J Epidemiol (1999); 150: 476-481
PMID: 10472947
One-year follow-up of newly diagnosed irritable bowel syndrome patients
Ruigomez A, Wallander MA, Johansson S, Garcia Rodriguez LA
Aliment Pharmacol and Ther (1999); 13: 1097-1102
PMID: 10468687
Minocycline and lupus-like syndrome in acne patients
Sturkenboom MCJM, Meier CR, Jick H, Stricker BHCH
Arch Int Med (1999); 159: 493-497
PMID: 10074958
Risk of idiopathic venous thromboembolism in users of progestagens alone (research letter)
Vasilakis C, Jick H, Melero-Montes MM
Lancet (1999); 354: 1610-1611
PMID: 10560680

24.
25.
26.
27.
28.
29.
30.
The risk of venous thromboembolism in users of postcoital contraceptive pills
Vasilakis C, Jick SS, Jick H
Contraception (1999); 59: 79-83
PMID: 10361621
Frequency of liver disease in type 2 diabetes patients treated with oral antidiabetic agents
Jick SS, Stender M, Myers MW
Diabetes Care (1999); 22: 2067-2071
PMID: 10587844
Risk of ventricular arrhythmias associated with nonsedating antihistamine drugs
De Abajo FJ, Garcia Rodriguez LA
Br J Clin Pharmacol (1999); 47: 307-313
PMID: 10215756
A cohort study on the risk of acute liver injury among users of ketoconazole and other antifungal drugs
Garcia Rodriguez LA, Duque A, Castellsague J, Perez Gutthann S, Stricker BHCH
Br J Clin Pharmacol (1999); 48: 847-852
PMID: 10594489
Oral contraceptives and venous thromboembolic disease. Analyses of the UK General Practices Research
Database and the UK MediPlus Database
Todd J-C, Williams TJ, MacRae K
Human Reproduction update (1999); 5:688-706
PMID: 10652979
Costs of breast cancer treatment in the United Kingdom
Dolan P, Torgerson DJ, Wolstenholme J
Breast (1999); 8: 205-207
PMID: 14731442
Outcomes of undernutrition in patients in the community with cancer or cardiovascular disease
Edington J, Winter PD, Coles SJ, Gale CR, Martyn CN
Proceedings of the Nutrition Society (1999); 58: 655-661
PMID: 10604199
1.
2.
3.
4.
Recent epidemiological studies of the association between hormone replacement therapy and venous thromboembolism. A review.
Castellsague J, Gutthann SP, Rodriguez LG
Drug Safety (1998); 18:117-123
PMID: 9512918
Why are patients prescribed proton pump inhibitors? Retrospective analysis of link between morbidity and prescribing in the General Practice Research Database
Bashford JNR, Norwood J, Chapman SR
Br Med J (1998); 317: 452-456
PMID: 9703528
Antiepileptics and blood dyscrasia: a cohort study
Blackburn SC, Duque Oliart A, Garcia Rodriguez LA, Perez Gutthann S
Pharmacotherapy (1998); 18: 1277-1283
PMID: 9855327
Recent developments in general practice computing
De Lusignan S, Brown A, Majeed A
Clinician in Management (1998); 7: 148-154

9.
5.
6.
7.
8.
10.
11.
12.
13.
14.
15.
Appendectomy protects against ulcerative colitis
Derby LE, Jick H
Epidemiology (1998); 9: 205-207
PMID: 9504292
The cost of treating osteoporotic fractures in the United Kingdom female population
Dolan P, Togerson DJ
Osteopor Int (1998); 8: 611-617
PMID: 10326069
Risk of hospitalization for upper gastrointestinal tract bleeding associated with ketorolac, other nonsteroidal anti-inflammatory drugs, calcium antagonists and other antihypertensive drugs
Garcia Rodriguez LA, Cattaruzzi C, Troncon MG, Agostinis L
Arch Int Med (1998); 158: 33-39
PMID: 9437376
Use of the UK General Practice Research Database for pharmacoepidemiolog y.
García Rodríguez LA, Pérez Gutthann S.
Br J Clin Pharmacol. 1998 May; 45(5):419-25.
PMID: 9643612
Comparison of mortality from peptic ulcer bleed between patients with or without peptic ulcer antecedents
Garcia Rodriguez LA, Ruigomez A, Hasselgren G, Wallander MA, Johansson S
Epidemiology (1998); 9: 452-456
PMID: 9647912
Presence of diabetes related complication at the time of NIDDM diagnosis: an important prognostic factor
Garcia Rodriguez LA, Ruigómez A, Hasselgren W, Wallander MA, Johansson S
Eur J Epidemiol (1998); 14: 439-445
PMID: 9744675
Relationship between the regional and national incidence of transient ischaemic attack and stroke and performance of carotid endarterectomy
Gibbs RGJ, Todd J-C, Irvine C, Lawrenson R, Newson R, Greenhalgh RM, Davies AH
Eur J Vasc Endovasc Surg (1998); 16: 47-52
PMID: 9715716
Potential for suicide prevention in primary care? An analysis of factors associated with suicide
Haste F, Charlton J, Jenkins R
Br J Gen Pract (1998); 48: 1759-1763
PMID: 10198484
Antidepressant exposure and risk of cryptogenic fibrosing alveolitis: a case-control study using the
General Practice Research Database
Hubbard R, Venn A, Lewis SA, Britton J
Thorax (1998); 53: S44
Exposure to commonly prescribed drugs and the etiology of cryptogenic fibrosing alveolitis: a case-control study
Hubbard R, Venn A, Smith C, Cooper M, Johnston I, Britton I
Am J Respir Crit Care Med (1998); 157: 743-747
PMID: 9517585
Influenza vaccine uptake and distribution in England and Wales, July 1989-June 1997
Irish C, Alli M, Gilham C, Joseph C, Watson J
Health Trends (1998); 30(2)
The risk of seizures associated with tramadol

16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
Jick H, Derby LE, Vasilakis C, Fife D
Pharmacotherapy (1998); 18: 607-611
PMID: 9620111
A population-based study of users of appetite-suppressant drugs on the risk of cardiac valve regurgitation.
Jick H, Vasilakis C, Weinrauch LA, Meier CR, Jick SS, Derby LE
N Engl J Med (1998); 339: 719-724
PMID: 9731087
Pregnancies and terminations after 1995 warning about third-generation oral contraceptives (research letter)
Jick SS, Vasilakis C, Jick H
Lancet (1998); 351: 1404-1405
PMID: 9593415
A study of the relation of exposure to quinolones and suicidal behaviour
Jick SS, Vasilakis C, Martinez C, Jick H
Br J Clin Pharmacol (1998); 45: 77-81
PMID: 9489598
Risk of serious haematological toxicity associated with the use of chloramphenicol eye drops in a British general practice database
Lancaster T, Swart AM, Jick H
Br Med J (1998); 316: 667
PMID: 9522792
Effect of nutritional status on use of health care resources by patients with chronic disease living in the community
Martyn CN, Winter PD, Coles SJ, Edington J
Clin Nut (1998); 17: 119-123
PMID: 10205328
Tamoxifen and risk of idiopathic venous thromboembolism
Meier CR, Jick H
Br J Clin Pharmacol (1998); 45: 608-612
PMID: 9663819
Acute respiratory tract infections and risk of first-time acute myocardial infarction
Meier CR, Jick SS, Derby LE, Vasilakis C, Jick H
Lancet (1998); 351: 1467-1471
PMID: 9605802
Postmenopausal estrogen replacement therapy and the risk of developing systemic lupus erythematosus or discoid lupus
Meier CR, Sturkenboom MCJM, Cohen AS, Jick H
J Rheumatol (1998); 25: 1515-1519
PMID: 9712093
Terfenadine and risk of acute liver disease
Myers MW, Jick H
Br J Clin Pharmacol (1998); 46: 251-253
PMID: 9764966
Mortality in people taking selegiline: observational study
Thorogood M, Armstrong B, Nichols T, Hollowell J
Br Med J (1998); 317: 252-254
PMID: 9677215
Use of cyclical etidronate and prevention of non-vertebral fractures van Staa TP, Abenhaim L, Cooper C

27. Br J Rheumatol (1998); 37: 87-94
PMID: 9487256
Postmarketing surveillance of the safety of cyclic etidronate van Staa TP, Leufkens H, Abenhaim L, Cooper C
28. Pharmacotherapy (1998); 18(5): 1121-1128
PMID: 9758324
29.
30.
Age-specific incidence and prevalence rates of treated epilepsy in an unselected population of 2 052 922 and age-specific fertility rates of women with epilepsy
Wallace H, Shorvon S, Tallis R
Lancet (1998); 352: 1970-1973
PMID: 9872246
Prescribing by general practitioners after an osteoporotic fracture
Torgerson DJ, Dolan P
Ann Rheumatic Diseases (1998); 25: 1515-1519
PMID: 9771215
1.
Gastric acid, acid-suppressing drugs and bacterial gastroenteritis: how much of a risk?
Garcia Rodriguez LA, Ruigomez A
2.
3.
4.
Epidemiology (1997); 8: 571-574
PMID: 9270961
A review of epidemiologic research on drug-induced acute liver injury using the General Practice
Research Database in the United Kingdom
Garcia Rodriguez LA, Ruigómez A, Jick H
Pharmacotherapy (1997); 17: 721-728
PMID: 9250549
Renal disease and acid-suppressing drugs
Garcia Rodriguez LA, Wallander MA, Johansson S, Bjork S
Pharmacoepidemiology and Drug Safety (1997); 6: 247-251
PMID: 15073775
The risk of acute liver injury associated with cimetidine and other acid-suppressing anti-ulcer drugs
Garcia Rodriguez LA, Wallander MA, Stricker BH
5.
6.
7.
Br J Clin Pharmacol (1997); 43: 183-188
PMID: 9131951
Thunderstorm-associated asthma: the effect on GP consultations
Hajat S, Goubet SA, Haines A
Br J Gen Pract (1997); 47: 639-641
PMID: 9474828
The General Practice Research Database: quality of morbidity data
Hollowell J
Populat Trends (1997); 87: 36-40
PMID: 9134574
Calcium-channel blockers and risk of cancer
Jick H, Jick SS, Derby LE, Vasilakis C, Myers MW, Meier CR
Lancet (1997); 349: 525-528
PMID: 9186407

8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
Antihypertensive drugs and fatal myocardial infarction in persons with uncomplicated hypertension
Jick H, Vasilakis C, Derby LE
Epidemiology (1997); 8(4): 446-448
PMID: 9209862
Ciprofloxacin safety in a pediatric population
Jick SS
Ped Infect Dis J(1997); 16: 130-134
Anticonvulsants and congenital malformations
Jick SS, Terris BZ
Pharmacotherapy (1997); 17: 561-564
PMID: 9165559
Omeprazole, other antiulcer drugs and newly diagnosed gout
Meier CR, Jick H
Br J Clin Pharmacol (1997); 44: 175-178
Omeprazole, H2-blockers and polyarthralgia: case control study
Meier CR, Jick H
Br Med J (1997); 315: 1283
PMID: 9390057
Drug use and pulmonary death rates in increasingly symptomatic asthmatics in the U.K.
Meier CR, Jick H
Thorax (1997); 52: 612-617
PMID: 9246132
Hormone replacement therapy and risk of venous thromboembolism: population based case-control study
Perez Gutthann S, Garcia Rodriguez LA, Castellsague Pique J, Duque Oliart A
Br Med J (1997); 314: 796-800
PMID: 9081000
Upper gastrointestinal adverse events and cyclical etidronate van Staa TP, Abenhaim L, Cooper C
Am J Med (1997); 103:467
PMID: 9428828
Rates of hypoglycemia in users of sulfonylureas van Staa TP, Abehaim L, Monette J
J Clin Epidemiol (1997); 50: 735-745
PMID: 9250272
5-Aminosalicylates, sulfasalazine, steroid use, and complications in patients with ulcerative colitis
Walker AM, Szneke P, Bianchi LA, Field LG, Sutherland LR, Dryer NA
Am J Gastroenterol (1997); 9: 816-820
PMID: 9149192
1.
Sudden unexplained death among subjects with refractory epilepsy
Derby LE, Tennis P, Jick H
Epilepsia (1996); 37(10): 931-935
PMID: 8822690

2.
3.
4.
5.
6.
7.
The use of the General Practice Research Database (GPRD) to examine potential links between antidepressant medication and the incidence of suicide
Donovan S
Drug Informat J (1996); 30: 785-792
A cohort study of the ocular safety of anti-ulcer drugs
Garcia Rodriguez LA, Mannino S, Wallander MA, Lindblom B
Br J Clin Pharmacol (1996); 42: 213-216
PMID: 8864320
Risk of acute liver injury associated with the combination of amoxicillin and clavulanic acid
Garcia Rodriguez LA, Stricker BH, Zimmerman HJ
Arch Int Med (1996); 156: 1327-1332
PMID: 8651842
Variability in risk of gastrointestinal complications with individual non-steroidal anti-inflammatory drugs: results of a collaborative meta-analysis
Henry D, Lim LL-Y, Garcia Rodriguez LA, Perez Gutthann S, Carson JL, Griffin M, Savage R, Logan R,
Moride Y, Hawkey C, Hill S, Fries JT
Br Med J (1996); 312: 1563-1566
PMID: 8664664
The risk of myocardial infarction associated with antihypertensive drug treatment in persons with uncomplicated essential hypertension
Jick H, Derby LE, Gurewich V, Vasilakis C
Pharmacotherapy (1996); 16(3): 321-326
PMID: 8726591
The demand for eating disorder care. An epidemiological study using the General Practice Research
Database
Turnbull SJ, Ward A, Treasure JL, Jick H, Derby LE
Br J Psychiatry (1996); 169: 705-712
1.
2.
3.
4.
Care of schizophrenia in general practice: the general practitioner and the patient
Nazareth I, King M, Davies S
Br J Gen Pract (1995); 45: 343-347
PMID: 7612336
Specific therapeutic group age-sex related prescribing units (STAR-PUs): weightings for analysing general practices’ prescribing in England
Lloyd DCEF, Harris CM, Roberts DJ
Br Med J (1995); 311: 991-994
PMID: 7580642
Hormone replacement therapy: characteristics of users and non-users in a British general practice cohort identified through computerised prescribing records
Lancaster T, Surman G, Lawrence M, Mant D, Vessey M, Thorogood M, Yudkin P, Daly E
J Epidemiol Commun Health (1995); 49:389-394
PMID: 7650462
Antidepressants and suicide
Jick SS, Dean AD, Jick H
Br Med J (1995); 310: 215-218
PMID: 7677826
The risk of sulfasalazine- and mesalazine-associated blood disorders

5.
6.
7.
8.
Jick H, Myers MW, Dean AD
Pharmacotherapy (1995); 15(2): 176-181
PMID: 7624265
Risk of idiopathic cardiovascular death and nonfatal venous thromboembolism in women using oral contraceptive with differing progestagen components
Jick H, Jick SS, Gurewich V, Myers MW, Vasilakis C
Lancet (1995); 346: 1589-1593
PMID: 7500750
A large population-based follow-up study of trimethoprim-sulfamethoxazole, trimethoprim, and cephalexin users for uncommon serious drug toxicity
Jick H, Derby LE
Pharmacotherapy (1995); 15(4): 428-432
PMID: 7479194
Ocular safety of antiulcer drugs (letter)
Garcia Rodríguez LA, Mannino S, Wallander MA
Lancet (1995); 345: 1059-1060
PMID: 7723534

1.
2.
3.
4.
5.
6.
7.
8.
9.
The quality of information recorded on a UK database of primary care records: A study of hospitalisations due to hypoglycemia and other conditions van Staa TP, Abenhaim L
Pharmacoepidemiology and Drug Safety (1994); 3: 15-21
The use of nitrates, calcium channel blockers and ACE Inhibitors in primary care in the Northern Region:
A Pharmacoepidemiological study
Roberts SJ, Bateman DN
Br J Clin Pharmacol (1994); 38: 489-497
PMID: 7888286
A study of the association between hormone replacement therapy, smoking and the occurrence of myocardial infarction in women
Mann RD, Lis Y, Chukwujindu J, Chanter DO
J Clin Epidemiol (1994); 47: 307-312
PMID: 8138842
The VAMP system and the detection of risk. Some examples
Mann RD
Pharmacotherapy (1994); 3: 313-319
Flucloxacillin and cholestatic hepatitis (letter)
Jick H, Derby LE, Dean AD, Henry DA
Med J Aust (1994); 160: 525
PMID: 8170433
Acute liver injury associated with nonsteroidal anti-inflammatory drugs and the role of risk factors
Garcia Rodríguez LA, Williams R, Derby LE, Dean AD, Jick H
Arch Int Med (1994); 154: 311-316
PMID: 8297198
Risk of upper gastrointestinal bleeding and perforation associated with individual nonsteroidal antiinflammatory drugs
Garcia Rodríguez LA, Jick H
Lancet (1994); 343: 769-772
PMID: 7907735
Risk of gynaecomastia associated with cimetidine, omeprazole, and other antiulcer drugs
Garcia Rodríguez LA, Jick H
Br Med J (1994); 308: 503-506
PMID: 8136667
Practice based information systems for monitoring medicines
Fleming DM
Pharmaceutical Medicine (1994); 8: 161-176

1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
Towards accurate prescribing analysis in general practice: accounting for the effects of practice demography
Sleator DJD
Br J Gen Pract (1993); 43: 102-106
PMID: 8323786
Accuracy of diagnosis of psychosis on general practice computer system
Nazareth I, King M, Haines A, Rangel L, Myers S
Br Med J (1993); 307: 32-34
PMID: 8343670
Care of schizophrenia in general practice
Nazareth I, King M, Haines A, See Tai S, Hall G
Br Med J (1993); 307:910
PMID: 8241855
A concurrent cohort study of oral contraceptive users from the VAMP research bank
Lis Y, Spitzer WO, Mann RD, Cockburn I, Chukwujindu J, Thorogood M, Evans S, Suissa S, Lelorier J
Pharmacoepidemiology and Drug Safety (1993); 2: 51-53
A follow-up safety study of ciprofloxacin users
Jick SS, Jick H, Dean AD
Pharmacotherapy (1993); 13: 461-464
PMID: 8247912
Nonsteroidal antiinflammatory drugs and certain rare, serious adverse effects. A cohort study
Jick H, Derby LE, Garcia Rodríguez LA, Jick SS, Dean AD
Pharmacotherapy (1993); 13:461-464
PMID: 8321735
Micturin (terodiline hydrochloride), torsades de pointe and other arrhythmias - a study using the VAMP database
Hall GC, Chukwujindu J, Richardson J, Lis Y, Wild RN
Pharmacoepidemiology and Drug Safety (1993); 2:127-132
Liver disorders in patients receiving chlorpromazine or isoniazid
Derby LE, Pérez Gutthann S, Jick H, Dean AD
Pharmacotherapy (1993); 13: 353-358
PMID: 8361861
Cholestatic hepatitis associated with flucloxacillin
Derby LE, Jick H, Henry DA, Dean AD
Med J Aust (1993); 159: 596-600
PMID: 8479374
Erythromycin-associated cholestatic hepatitis
Derby LE, Jick H, Henry DA, Dean AD
Med J Aust (1993); 158: 600-602
PMID: 8479375
Micturin and torsades de pointe-experience of a post-marketing alert
Wild RN

1. Pharmacoepidemiology and Drug Safety (1992); 1: 147-150
2.
Urinary tract infections and estrogen use in older women
Orlander JD, Jick SS, Dean AD, Jick H
J Am Geriatr Soc (1992); 40: 817-820
PMID: 1634725
3.
NSAIDs, quinolones and convulsions: an epidemiologic approach
Mannino S, Garcia Rodríguez LA, Jick SS
4.
Post Marketing Surveillance (1992); 6: 119-128
Research implications of computerised primary care
Mann RD, Hall G, Chukwujindu J
Post Marketing Surveillance (1992): 5(3): 259-268
5.
6.
7.
Antidepressants and convulsions
Jick SS, Jick H, Knauss TA, Dean AD
J Clin Psychopharmacol (1992); 12: 241-245
PMID: 1527226
Comparison of frequencies of suicidal tendencies among patients receiving fluoxetine, lofepramine, mianserin or trazodone
Jick H, Ulcickas M, Dean AD
Pharmacotherapy (1992); 12: 451-454
PMID: 1492009
Further validation of information recorded on a general practitioner based computerised data resource in the United Kingdom
Jick H, Terris BZ, Derby LE, Jick SS
Pharmacoepidemiology and Drug Safety (1992); 1:347-349
8.
9.
Liver disease associated with diclofenac, naproxen and piroxicam
Jick H, Derby LE, Garcia Rodriguez LA, Jick SS, Dean AD
Pharmacotherapy (1992); 12: 207-212
PMID: 1608854
Antidepressant drugs and suicide
Derby LE, Jick H, Dean AD
J Clin Psychopharmacol (1992); 12: 235-240
PMID: 1527225
1.
2.
How common are epileptic seizures in old age?
Tallis R, Hall G, Craig I, Dean A
Age and Ageing (1991); 20: 442-448
PMID: 1776595
Validation of information recorded on general practitioner based computerised data resource in the
United Kingdom
Jick H, Jick SS, Derby LE
Br Med J (1991); 302: 766-768
PMID: 2021768
A total audit of preventive procedures in 45 practices caring for 430 000 patients

3.
4.
5.
Lawrence M, Coulter A, Jones L
Br Med J (1990); 300: 1501-1503
PMID: 2372603
A comparison of the risk of hypoglycemia between users of human and animal insulins. Experience in the
United Kingdom
Jick H, Hall GC, Dean AD, Jick SS, Derby LE
Pharmacotherapy (1990); 10(6): 395-397
PMID: 2287559
Post marketing surveillance using a computerised general practice data base
Hall GC, Luscombe DK, Walker SR
Pharmaceutical Medicine (1988); 2: 345-351
1.
2.
3.
4
5
6
7
8
Changes over time in treatment persistence of oral anticoagulants in patients with non-valvular atrial fibrillation.
Lefevre C, Johnson M, Collings S, Evans D, Kloss S, Ridha E, Maguire A.
J Am Coll Cardiol 2016 Apr 05;67(13):769.
Comparison of treatment persistence in the real-world use of novel oral anticoagulants among patients with non-valvular atrial fibrillation.
Lefevre C, Johnson M, Collings S, Evans D, Kloss S, Ridha E, Maguire A.
J Am Coll Cardiol 2016 Apr 05;67(13):792.
Anticoagulation control in patients with non-valvular atrial fibrillation treated with vitamin k antagonist therapy for 12 months or more in primary care in the UK.
Ridha E, Donaldson R, Lefevre C, Ramagopalan S, Lister S, Jenkins A, Evans D, Minns I, Lacoin
L.
J Am Coll Cardiol 2016 Apr 05;67(13):889.
Social gradient and regional variation and in general practice consultation prevalence for osteoarthritis in England 1998-2013: Descriptive epidemiological study using data from the clinical practice research datalink.
Dutta A, Wilkie R, Yu D, Peat G.
Osteoarthritis and Cartilage 2016 04;24:S197-S198.
Stratification using gender and body mass index (BMI) results in better glycaemic control for longer: A mastermind study.
Shields B, Dennis J, Rodgers L, Jones A, Lonergan M, Henley W, Holman R, Pearson E,
Hattersley A.
Diabetic Med 2016 03;33:10-11.
Incidence and prevalence of diabetic eye disease: A comprehensive profile of diabetic retinopathy and subsequent visual impairment in the UK.
Mathur R, Douglas I, Edwards E, Slade J, Bhaskaran K, Smeeth L.
Diabetic Med 2016 03;33:11.
Initial HbA1c greatly impacts response to oral hypoglycaemic agents but should not be used to define choice of therapy: A mastermind study.
Jones AG, Dennis DM, Shields BM, Pearson ER, Hattersley AT.
Diabetic Med 2016 03;33:31.
Type 2 diabetes therapies and cardiovascular disease: Examining the risk of major cardiovascular events during second-line antidiabetic treatments using the Clinical Practice
Research Datalink (CPRD).
Zghebi SS, Steinke DT, Rutter MK, Emsley RA, Ashcroft DM.
Diabetic Med 2016 03;33:97-98.

9
10
11
12
Use of dipeptidylpeptidase-4 inhibitor (DPP-4) in patients with Type 2 diabetes and reduced renal function: A CPRD study.
Lee S, Spencer W, Bingham-Gardiner P, Hassan S, Bolodeoku J, Ruffolo A, Kandawamy P,
Scowcroft A.
Diabetic Med 2016 03;33:136.
Personalisation of treatment with metformin by age, weight and sex: A MASTERMIND study.
Lonergan ME, Shields B, Agbaje OF, Dennis J, Weeden M, Rodgers L, Holman RR, Hattersley A,
Pearson EW.
Diabetic Med 2016 03;33:194.
Incidence of stroke in and around pregnancy: A UK population-based cohort study.
Ban L, Sprigg N, Sultan AA, Nelson-Piercy C, Bath PM, Tata LJ.
Stroke 2016 02;47.
Allopurinol use and risk of atrial fibrillation.
Boyle S, MacIsaac RL, Padmanabhan S, Walters M, Touyz R, Dominiczak A, Dawson J.
Stroke 2016 02;47.
1.
2.
3.
4.
5.
6.
7.
8.
Predictors of major bleeding in patients with first venous thromboembolism treated with vitamin K antagonists in clinical practice in the United Kingdom.
Cohen AT, Wallenhorst C, Katholing A, Hamilton M, Unniachan S, Martinez C.
Blood 2015 Dec 03;126(23):2327.
Recording of hospitalisations for acute exacerbations of COPD in UK electronic healthcare records databases.
Rothnie KJ, Mullerova H, Hurst JR, Smeeth L, Chandan J, Davis K, Thomas S, Quint JK.
Thorax 2015 12;70:A99.
Health care utilisation and costs among COPD patients newly prescribed maintenance therapy in the United Kingdom (UK).
Punekar Y, Landis SH, Bonar K, Le H.
Thorax 2015 12;70:A142-A143.
Evaluation of exacerbation frequency and rehospitalisation, and risk for subsequent exacerbations in asthma patients in a UK primary care setting.
Suruki RY, Daugherty JB, Boudiaf N, Albers FC.
Thorax 2015 12;70:A188.
Validity and interpretation of spirometry for patients in primary care.
Rothnie KJ, Mullerova H, Goss H, Chandan J, Quint JK.
Thorax 2015 12;70:A188-A190.
Rates of cardiovascular events in patients receiving high-intensity statin therapy in the United
Kingdom.
Taylor B, Danese M, Villa G, Lothgren M, Khunti K, Ray K.
Circulation 2015 Nov 10;132.
Differences between observed and predicted cardiovascular event rates using the framingham and reach equations: The case of high-intensity statin users in the United Kingdom.
Taylor B, Lothgren M, Villa G, Lindgren P, Van Hout B, Mark D.
Circulation 2015 Nov 10;132.
Time-dependent markers of chronic obstructive pulmonary disease severity and change are associated with increased risk of mortality in the general heart failure population: A national study of 50,114 patients from the United Kingdom.
Rushton CA, Riley L, Satchithananda DK, Jones PW, Kadam UT.

9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
Circulation 2015 Nov 10;132.
Co-administration of proton pump inhibitors in chronic aspirin users and the risk of adverse cardiovascular events: A population-based cohort study.
Tran-Duy A, Vanmolkot FH, Souverein PC, Hoes AW, De Boer A, Stehower CD, De Wit NJ, Joore
MA, De Vries F.
Value in Health 2015 11;18(7):A378.
The comparative risk of all-cause mortality in older patients prescribed opioids for nonmalignant pain: A retrospective observational cohort study.
Allen C, Meeraus W, Donegan K.
Drug Safety 2015 10;38(10):962-963.
Factors Associated With The Duration Of Anticoagulation Therapy Following Acute Vte In
England In General Practice: An Observational Study Using Cprd-Hes Databases.
Lacoin L, Ridha E, Lefevre C, Moorthy V, Vasudev M, Lister S, Bird A, Minns I, Evans D, Alikhan
R, Bakhai A.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes
Research 2015 11;18(7):A401.
Antidepressant use in Patients with Major Depressive Disorder: a Comparison of Treatment
Resistant and Non-Treatment Resistant Episodes in the United Kingdom Using The CPRD
Database.
Kubitz N, Potluri R, Mehra M.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes
Research 2015 11;18(7):A414.
Retrospective Cohort Study Using Data From The Uk Clinical Practice Research Datalink and
Hospital Episode Statistics to Assess Unplanned Hospitalisation In Patients With Multiple
Myeloma.
Raluy-Callado M, Lambrelli D, DeCosta L, Gonzalez-McQuire S.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes
Research 2015 11;18(7):A672.
The Use of Real World Evidence to Influence Practice: A Systematic Review of CPRD Studies In
English Guidances And Guidelines.
Oyinlola JO, Campbell J, Kousoulis AA.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes
Research 2015 11;18(7):A565.
Co-administration of proton pump inhibitors in chronic aspirin users and the risk of adverse cardiovascular events: A population-based cohort study.
Tran-Duy A, Vanmolkot FH, Souverein PC, Hoes AW, De Boer A, Stehower CD, De Wit NJ, Joore
MA, De Vries F.
Value in Health 2015 11;18(7):A378.
Costs of cardiovascular (CV) events in the United Kingdom (UK) using real-world data.
Danese M, Gleeson M, Kutikova L, Griffiths R, Azough A, Khunti K, Kondapally Seshasai SR, Ray
KK.
Value in Health 2015 11;18(7):A387.
Resource utilisation and bleeding events during anticoagulation treatment: Real-world findings from England.
Lister S, Lefevre C, Menown I, Alikhan R, Lacoin L, Bird A, You M, Ridha E, Evans D.
Value in Health 2015 11;18(7):A396-A397.
Factors associated with the duration of anticoagulation therapy following acute VTE in England in general practice: An observational study using CPRD-HES databases.
Lacoin L, Ridha E, Lefevre C, Moorthy V, Vasudev M, Lister S, Bird A, Minns I, Evans D, Alikhan
R, Bakhai A.
Value in Health 2015 11;18(7):A401.
19. Angiotensin converting enzyme inhibitors prescribing pattern for different indications: A

20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31. population based study.
Mahmoudpour SH, Asselbergs FW, Souverein PC, De Boer A, Maitland-Van DZ.
Value in Health 2015 11;18(7):A402.
Lipid modifying therapy treatment patterns and cholesterol control after cardiovascular events in the United Kingdom.
Danese M, Gleeson M, Kutikova L, Griffiths R, Khunti K, Kondapally Seshasai SR, Ray KK.
Value in Health 2015 11;18(7):A406.
Antidepressant use in patients with major depressive disorder: A comparison of treatment resistant and non-treatment resistant episodes in the United Kingdom using the CPRD database.
Kubitz N, Potluri R, Mehra M.
Value in Health 2015 11;18(7):A414.
Drug utilization pattern of lisdexamfetamine dimesylate in Europe.
Cook MN, Varughese S, Maxwell T, Thun B, Ehlken B, Von Bredow D, Keja J.
Value in Health 2015 11;18(7):A414.
Resource use and exac erbations of chronic obstructive pulmonary disease (COPD) by gold categories.
Merinopoulou E, Raluy-Callado M, Ramagopalan S, MacLachlan S, Khalid JM.
Value in Health 2015 11;18(7):A506-A507.
Association of adverse events and health service usage with tapentadol prolonged-release treatment compared with morphine controlled-release (CR) and oxycodone CR: A UK primary care observational study.
Baxter G, Morgan CL, Jenkins-Jones S, Currie CJ, Schultewolter D.
Value in Health 2015 11;18(7):A658.
Prevalence of antidepressants prescribed to tramadol users in the UK primary care setting-a prescription sequence symmetry analysis.
Chen T, Chen L, Knaggs RD.
Value in Health 2015 11;18(7):A661.
The feasibility of applying definitions of persistent opioid utilisation to quantify the persistency of tramadol users.
Chen T, Chen L, Knaggs RD.
Value in Health 2015 11;18(7):A679.
Cart analysis as a tool to determine optimal treatment intensification time in diabetes.
Watson L, Farquhar R, Das R, Flynn A.
Value in Health 2015 11;18(7):A682.
Comparison of comorbidity measures to predict economic outcomes in a large UK primary care database.
Bessou A, Guelfucci F, Aballea S, Toumi M, Poole C.
Value in Health 2015 11;18(7):A691.
Using machine learning to detect patients with undiagnosed rare diseases: An application of support vector machines to a rare oncology disease.
Rigg J, Lodhi H, Nasuti P.
Value in Health 2015 11;18(7):A705.
The burden of illness of congenital adrenal hyperplasia in the united kingdom: A retrospective, observational study.
Jenkins-Jones S, Whitaker MJ, Holden SE, Morgan CL, Ross RJ, Currie CJ.
Value in Health 2015 11;18(7):A749.
Preliminary results of bladder cancer risk in relation to exposure to pioglitazone among patients with T2DM in the pan european multi-database bladder cancer risk characterisation study.
Korhonen P, Heintjes EM, Williams R, Hoti F, Christopher S, Majak M, Bezemer I, Houweling L,
Strongman H, Williams T, Linder M, Dolin P, Bahmanyar S.

32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
Pharmacoepidemiol Drug Saf 2015 09;24:31-32.
A method to identify patients included within both the clinical practice research datalink (CPRD) and the health improvement network (THIN).
Saine ME, Carbonari DM, Newcomb CW, Blak B, Roy J, Haynes K, Wood J, Gallagher AM,
Bhullar H, Cardillo S, Hennessy S, Strom BL, Re III VL.
Pharmacoepidemiol Drug Saf 2015 09;24:569-570.
Concordance of hospitalizations within the clinical practice research datalink (CPRD) and hospital episode statistics (HES) among type 2 diabetes mellitus patients.
Saine ME, Carbonari DM, Newcomb CW, Roy JA, Haynes K, Wood J, Gallagher AM, Cardillo S,
Hennessy S, Strom BL, Re III VL.
Pharmacoepidemiol Drug Saf 2015 09;24:570-571.
Completeness of key variables in the clinical practice research datalink (CPRD).
Herrett E, Gallagher A, Bhaskaran K, Forbes H, Mathur R, Van Staa T, Smeeth L.
Pharmacoepidemiol Drug Saf 2015 09;24:586-587.
Impact of unresolved chronic rhinosinusitis on incidence of asthma.
Hopkins C, Holy C, Sindwani R, Micheal B.
Allergy: European Journal of Allergy and Clinical Immunology 2015 09;70:108.
Direct medical costs of severe hypoglycaemic events amongst type 2 diabetes patients in the
UK: A retrospective database study.
Tunceli K, Holbrook T, Williams J, Shankar R, Chen J, Radican L, Piercy J.
Diabetologia 2015 09;58(1):S158.
Characteristics of newly diagnosed adults with type 1 diabetes in the UK and their evolution over the first 5 years.
Ramtoola S, Ploug UJ, Kragh N, Nyeland ME.
Diabetologia 2015 09;58(1):S170.
Development of oedema is associated with an improved glycaemic response in patients initiating thiazolidinediones: A MASTERMIND study.
Dennis JM, Hattersley AT, Weedon M, Angwin C, Rodgers L, Pearson ER, Henley WE, Shields
BM.
Diabetologia 2015 09;58(1):S342.
The impact of delaying treatment intensification in type 2 diabetes: Evidence from UK general practice.
Das R, Watson L, Farquhar R, Langerman H, Barnett AH.
Diabetologia 2015 09;58(1):S347.
Changes in HbA1c and weight in type 2 diabetes patients initiating dapagliflozin treatment in routine UK primary care.
Wilding JPH, Bailey CJ, Rigney U, Blak B, Beekman W, Emmas CE.
Diabetologia 2015 09;58(1):S352-S353.
Non-adherence and non-persistence related to GLP-1 therapy in patients with type 2 diabetes mellitus: Analysis of a large UK CPRD dataset.
Wilke T, Berg B, Groth A, Martin A, Logie J, Sikirica M.
Diabetologia 2015 09;58(1):S385.
Patient characteristics are associated with treatment response to second line glucose lowering therapy: A MASTERMIND study.
Shields BM, Lonergan M, Dennis J, Jones A, Rogers L, Weedon M, Donnelly L, Holman R, Henley
W, Pearson E, Hattersley A.
Diabetologia 2015 09;58(1):S405.
Management and mortality in very old patients with type 2 diabetes.
Hamada S, Gulliford MC.
Diabetologia 2015 09;58(1):S431-S432.

44.
45.
46.
47
48
49
50
51
52
53
54
55
Trends in Long-Term Opioid Prescribing in Primary Care Patients with Musculoskeletal
Conditions: An Observational Database Study.
Bedson J, Chen Y, Hayward R, Jordan K.
Rheumatology 2015;54:i158-i158.
Quantification of risk factors for postherpetic neuralgia in a cohort of herpes zoster patients.
Forbes H, Bhaskaran K, Thomas S, Smeeth L, Clayton T, Mansfield K, Minassian C, Langan S.
J Invest Dermatol 2015 09;135:S33.
Determinants of oral anticoagulation control in new warfarin patients: Analysis using data from clinical practice research datalink.
Macedo AF, Bell J, Mc Carron C, Conroy R, Richardson J, Scowcroft A, Sunderland T, Rotheram
N.
Eur Heart J 2015 Aug 01;36:745.
High burden of potentially avoidable stroke from discontinuation of warfarin therapy in nonvalvular atrial fibrillation.
Freedman SB, Martinez C, Wallenhorst C, Katholing A.
Eur Heart J 2015 Aug 01;36:862.
Increasing incidence of non-valvular atrial fibrillation (AF) between 2001-2013 in the UK:
Largely due to non-primary AF hospital diagnosis in the elderly.
Martinez C, Katholing A, Wallenhorst C, Freedman SB.
Eur Heart J 2015 Aug 01;36:913-914.
Patient profile of oral anticoagulation (OAC) use in people with non-valvular atrial fibrillation
(NVAF): Findings from REACT-AF 2 study in UK primary care data.
Benhaddi H, Johnson M, Maguire A, Collings SL, Evans D, Budd D.
Eur Heart J 2015 Aug 01;36:1078.
Management of anticoagulation in patients with non-valvular atrial fibrillation in general practice in UK: Evolution and characteristics of patients not treated with antithrombotic therapy.
Lacoin L, Ridha E, Lefevre C, McGuigan S, Ramagopalan S, Jenkins A, Evans D, Minns I, Halcox
J.
Eur Heart J 2015 Aug 01;36:1081.
Management of anticoagulation in patients with non-valvular atrial fibrillation in general practice in UK: Evolution and characteristics of patients treated with antiplatelet therapy alone.
Ridha E, Lacoin L, Donaldson R, Lefevre C, Ramagopalan S, Jenkins A, Evans D, Minns I, Halcox
J.
Eur Heart J 2015 Aug 01;36:1085-1086.
Personal history of infections associated with an increased risk of monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma: A population-based nested casecontrol study.
Mcshane C, Murray LJ, Landgren O, Bradley MC, Hughes C, Anderson LA.
Haematologica 2015 Jun 22;100:498.
Burden of multiple myeloma in the United Kingdom.
Raluy-Callado M, Lambrelli D, Merinopoulou E, Panjabi S.
Haematologica 2015 Jun 22;100:739.
Duration of anticoagulation following acute venous thromboembolism in routine care in
England: An observational study using CPRD-HES databases.
Lacoin L, Ridha E, Lefevre C, Moorthy V, Vasudev M, Lister S, Bird A, Minns I, Bakhai A, Alikhan
R.
Journal of Thrombosis and Haemostasis 2015 06;13:242.
Surgery for perianal crohn's disease: UK national population based cohort study.
Chhaya V, Saxena S, Cecil E, Curcin V, Subramanian V, Majeed A, Pollok R.
Gut 2015 06;64:A444-A445.

56
57
58
59
60
61
62
63
64
65
66
67
68
Linked hospital and primary care database study of venous thromboembolism and associated mortality following general surgical procedures in England.
Bouras G, Burns EM, Howell A-, Bottle A, Athanasiou T, Darzi A.
Gut 2015 06;64:A44-A45.
Linked primary care and hospital database analysis of trends in laparoscopy, short-term complications and recurrence following inguinal hernia repair in England.
Bouras G, Burns EM, Bottle A, Athanasiou T, Darzi A.
Gut 2015 06;64:A185-A186.
Combined effects of reoperation and venous thromboembolism in gastrointestinal surgery:
Evaluation of postoperative complications using linked hospital and primary care data.
Bouras G, Burns EM, Bottle A, Clarke J, Athanasiou T, Darzi A.
Gut 2015 06;64:A277-A278.
Treatment patterns and characteristics of patients with type 2 diabetes (T2D) managed with basal-bolus therapy in the UK.
Van Brunt K, Curtis BH, Chalkiadaki C, Balogh E, Ivanyi T, Raluy M, Maclachlan S.
Diabetes 2015 06;64:A696-A697.
Relationship between vitamin k antagonists and recurrent bleeding events in patients with nonvalvular atrial fibrillation: Real-world findings from England.
Alikhan R, Lefevre C, Menown I, Lister S, Lacoin L, Bird A, You M, Ridha E, Evans D.
Journal of Thrombosis and Haemostasis 2015 06;13:493-494.
Mortality following venous thromboembolism: A population-based cohort study in patients with active cancer.
Martinez C, Katholing A, Rietbrock S, Cohen A.
Journal of Thrombosis and Haemostasis 2015 06;13:554.
Psychotropic prescribing in young people with ADHD in the UK clinical practice research data link: 2005-2014.
Newlove Delgado T, Hamilton W, Ford T, Stein K, Ukoumunne O.
European Child and Adolescent Psychiatry 2015 06;24(1):S162.
Epidemiology of first venous thromboembolism in patients with active cancer.
Cohen A, Katholing A, Rietbrock S, Martinez C.
Journal of Thrombosis and Haemostasis 2015 06;13:208.
The use of 5-ASA in inflammatory bowel disease: National population based study.
Chhaya V, Saxena S, Cecil E, Subramanian V, Curcin V, Majeed A, Pollok R.
Gut 2015 06;64:A444.
Risk of recurrent venous thromboembolism in patients with active cancer.
Cohen A, Rietbrock S, Katholing A, Martinez C.
Journal of Thrombosis and Haemostasis 2015 06;13:30.
Risk of community-acquired pneumonia among patients with coeliac disease compared to the general population: A population based cohort study.
Zingone F, Abdul Sultan A, Crooks CJ, Tata L, Ciacci C, West J.
Gut 2015 06;64:A129-A130.
Trends in the use of NSAIDs and aspirin and the use of proton pump inhibitors for gastroduodenal protection in the UK: A cross-sectional study using the CPRD database.
Lewis N, Vinogradova Y, Hawkey CJ.
Gut 2015 06;64:A484-A485.
Taking less oral glucose-lowering treatment than prescribed is associated with a reduced improvement in 12-month HbA1c: A retrospective mastermind cohort analysis stratified by type of treatment.
Farmer AJ, Rodgers LR, Lonergan M, Weedon MN, Shields B, Donnelly L, Holman RR, Pearson
ER, Hattersley AT, Consortium M.
Diabetes 2015 06;64:A652.

69
70
71
72
73
74
75
76
77
78
79
80
Factors predictive of weight gain and implications for diabetes modelling: A study in type 2 diabetes patients initiating metformin and sulphonylurea combination therapy.
Gordon J, Mcewan PC, Sugrue D, Puelles J.
Diabetes 2015 06;64:A356.
Association of oral and intravenous iron with the probability of hospitalisation in England.
Keshav S, Chapman C, Tomkins S, Mills L, Jackson B.
Gut 2015 06;64:A18.
Baseline characteristics of uk patients with type 2 diabetes and chronic kidney disease initiating therapy with sitagliptin.
Mcneill AM, Brodovicz KG, Chen Y, O'Neill EA, Liao J, Ommen ES, Engel SS.
Diabetes 2015 06;64:A696.
Chronic hand eczema in the Clinical Practice Research Datalink (CPRD): Prevalence, incidence, comorbidities, and initial treatment.
Crane MM, Webb DJ, Watson ED, Cunliffe T, English J.
J Am Acad Dermatol 2015 05;72(5):AB95.
Cost of primary and secondary healthcare utilization for patients with irritable bowel syndrome calculated using routinely collected electronic records to assess the impact of secondary care referral.
Canavan C, Card T, West J.
Value in Health 2015 05;18(3):A270.
SSRI use in pregnancy: A study in 6 European databases.
Jordan S, Charlton RA, Tingay K, Thayer DS, Davies GI, Morgan M, Tucker D, Watkins A, Gini R,
Pierini A, Hansen A, Garne E, Nybo A, Puccini A, Neville AJ, Bos HJ, De Jong-Van DB, De Vries
CS, Dolk H, Petersen I, Man S.
Archives of Women's Mental Health 2015 04;18(2):368.
DPP-4 inhibitors and the risk of community-acquired pneumonia in patients with type 2 diabetes.
Faillie JL, Filion KB, Patenaude V, Ernst P, Azoulay L.
Fundamental and Clinical Pharmacology 2015 04;29:3.
Steroid dependency in inflammatory bowel disease: National population based study.
Chhaya V, Saxena S, Cecil E, Subramanian V, Curcin V, Majeed A, Pollok R.
Gastroenterology 2015 04;148(4):S830.
Benzodiazepines and Dementia outcomes: A retrospective, matched cohort study using CPRD.
Campaigno PD, Lapeyre-Mestre M, Delpierre C, Rousseau V.
Fundamental and Clinical Pharmacology 2015 04;29:41.
91-94% SVR24 in HCV/HIV-1 co-infected patients treated with ombitasvir/paritaprevir/r and dasabuvir with ribavirin.
Wang C, Trinh R, Ruane P, Wyles D, Eron J, Bhatti L, Hu Y, McGovern B, Shulman N, Sulkowski
M.
Journal of the International AIDS Society 2015 04;18:14-15.
Patient characteristics influence treatment response to second line glucose lowering therapy in two large UK cohorts: A MASTERMIND study.
Shields BM, Lonergan M, Jones A, Rodgers L, Weedon M, Donnelly LA, Holman RR, Pearson ER,
Hattersley AT.
Diabetic Med 2015 03;32:2.
Patients who develop oedema on initiating thiazolidinedione therapy have an improved glycaemic response: A Mastermind study.
Dennis JM, Hattersley AT, Weedon M, Angwin CD, Rodgers L, Pearson ER, Henley WE, Shields
BM.
Diabetic Med 2015 03;32:94.

81
82
83
84
85
86
87
88
89
90
91
92
Choice of second-line antidiabetic treatment in Type 2 diabetes: Influence of patient characteristics.
Zghebi SS, Steinke DT, Rutter MK, Ashcroft DM.
Diabetic Med 2015 03;32:205.
Increased risk of cardiovascular events as a result of delay in treatment intensification for patients with Type 2 diabetes.
Khunti K, Paul S, Thorsted BL, Wolden ML, Klein K.
Diabetic Med 2015 03;32:116.
Inpatient hypoglycaemia increases length of hospital stay and all-cause mortality risk.
Evans M, Wolden ML, Thorsted BL, McEwan PC, Jacobsen JL.
Diabetic Med 2015 03;32:23.
Metformin, in contrast to thiazolidinediones, works best in slim, insulin sensitive patients: A
MASTERMIND study.
Lonergan M, Agbaje OF, Shields BM, Weeden M, Rodgers L, Donnelly LA, Hattersley AT, Holman
RR, Pearson ER.
Diabetic Med 2015 03;32:1.
Inflammatory bowel disease and the risk of other autoimmune diseases.
Wilson JC, Furlano R, Jick S, Meier C.
Journal of Crohn's and Colitis 2015 02;9:S410-S411.
Prolonged and repeated steroid exposure in inflammatory bowel disease: National population based study.
Chhaya V, Saxena S, Cecil E, Subramanian V, Curcin V, Majeed A, Pollok R.
Journal of Crohn's and Colitis 2015 02;9:S269.
Medication-induced microscopic colitis: Do recency and duration of use matter?
Verhaegh BPM, De Vries F, Masclee AA, Keshavarzian A, De Boer A, Souverein P, Jonkers DM,
Pierik MJ.
Journal of Crohn's and Colitis 2015 02;9:S6-S7.
Early thiopurine use is associated with a reduced risk of surgery in children and young people with Crohn's disease but not in ulcerative colitis.
Chhaya V, Pollok R, Cecil E, Subramanian V, Curcin V, Majeed A, Saxena S.
Journal of Crohn's and Colitis 2015 02;9:S52-S53.
Long-term utilization differences between children treated with clobazam vs. Clonazepam for epilepsy in the UK.
Chung SS, Brodie M, Wade AG, Quelen C, Guiraud-Diawara A, Franc¸ois C, Verpillat P, Shen V,
Jones D, Isojarvi J.
Epilepsy Currents 2015 Jan;15:158.
Clobazam vs. Clonazepam for adults with epilepsy: Long-term results from a UK primary care database.
Brodie M, Chung SS, Wade AG, Quelen C, Guiraud-Diawara A, Franc¸ois C, Verpillat P, Shen V,
Jones D, Isojarvi J.
Epilepsy Currents 2015 Jan;15:157.
Real-world assessment of the burden of epilepsy in tuberous sclerosis complex (TSC) patients in the United Kingdom (UK).
Crawford P, Shepherd C, Demuth D, Nasuti P, Lucchese L, Haider Z, Gray E, Magestro M.
Epilepsy Currents 2015 Jan;15:446.
Evolution of clobazam, clonazepam, and diazepam usage in the UK for epilepsy and other diseases.
Jones D, Chung SS, Brodie M, Wade AG, Quelen C, Guiraud-Diawara A, Verpillat P, Shen V,
Isojarvi J,Franc¸ois C.
Epilepsy Currents 2015 Jan;15:158.

93
Effect of cesarean deliveries on the risk of hospital admissions for small bowel obstruction.
Abenhaim H, Wilchesky M, Platt R, Eberg M, Tulandi T, Suissa S, Filion K.
Obstet Gynecol 2015 01;212(1):S388.
Psoriasis and the risk of stroke: A populationbased cohort study.
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
Parisi R, Rutter MK, Lunt M, Young HS, Symmons DPM, Griffiths CEM, Ashcroft DM.
Br J Dermatol 2014 12;171(6):e116-e117.
The association between exacerbation frequency and stroke risk, in patients with COPD: A matched case-control study.
Windsor CL, Herrett E, Smeeth L, Quint J.
Thorax 2014 12;69:A214.
Cardiovascular risk factors in people with bronchiectasis: A cross sectional study.
Navaratnam V, Millett E, Hurst JR, Thomas SL, Smeeth L, Hubbard RB, Brown J, Quint JK.
Thorax 2014 12;69:A11-A12.
Adherence to nice guidance for initiating GLP-1 mimetics among patients with type 2 diabetes in primary care in england and wales-an evaluation using the clinical practice research datalink
(CPRD).
Jameson K, D'Oca K, Murray-Thomas T, O'Regan C, Leigh P.
Value in Health 2014 11;17(7):A362.
Trends in anti-osteoporosis drug prescribing after hip fracture in the United Kingdom: 2000-
2010.
Gibson-Smith D, Klop C, Elders P, Welsing P, Leufkens H, Harvey N, Van Staa T, De Vries F.
Osteoporosis Int 2014 11;25(6):S677-S678.
Stroke prevention in elderly with atrial fibrillation: Evidence from RCTS and epidemiological studies-new insights.
Thrift A.
Neuroepidemiology 2014 11;43(2):73.
The efficacy and effectiveness in HbA1c-lowering is dependent on baseline body mass index
(BMI) for sitagliptin but not canagliflozin in the treatment of type 2 diabetes mellitus (T2DM).
Diels J, Angermund R, Schroeder M, Worbes-Cerezo M, Thompson G.
Value in Health 2014 11;17(7):A334.
Estimation of increased costs in switching from tiotropium to other lama therapy during maintenance treatment of COPD in the UK.
Ternouth A, Schoenherr N, Edwards SC.
Value in Health 2014 11;17(7):A591-A592.
History of antidepressant use among primary care depressed patients switching treatments in the United Kingdom.
Lamy FX, Quelen C, Brignone M, Ferchichi S, Vataire AL, Rive B, Saragoussi D.
Value in Health 2014 11;17(7):A466.
Patient characteristics and medication treatment patterns among men with erectile dysfunction
(ED), lower urinary tract symptoms secondary to benign prostatic hyperplasia (BPH-LUTS), or co-occurring ED and BPH-LUTS in the UK primary care setting.
Ilo D, Raluy-Callado M, Graham-Clarke P, Donaldson R, Birt J, Sadasivan R, Zhu Y, Neasham D.
Value in Health 2014 11;17(7):A521.
Cost of previously treated chronic lymphocytic leukemia (CLL) and indolent non-hodgkin's lymphoma (INHL) in the United Kingdom (UK).
Cognet M, Druais S, Gervais F, Gauthier A, Abrams KR.
Value in Health 2014 11;17(7):A549.
Bisphosphonates and risk of acute pseudogout: A case-control study in the clinical practice research datalink (CPRD).
Roddy E, Muller S, Paskins Z, Hider S, Blagojevic-Bucknall M, Mallen C.
Arthritis and Rheumatology 2014 10;66:S366.
Assessment of daily dose of domperidone in the clinical practice research datalink (CPRD) using multiple information sources.
Arana A, Johannes C, Varas C, Rothman KJ, McQuay LJ, Yang Q, Fife D.
Pharmacoepidemiol Drug Saf 2014 10;23:329-330.

14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
Psoriasis and the risk of stroke: A population-based cohort study using the clinical practice research datalink (cprd).
Parisi R, Rutter MK, Lunt M, Young HS, Symmons DPM, Griffiths CEM, Ashcroft DM.
Pharmacoepidemiol Drug Saf 2014 10;23:444-445.
Spironolactone and incidence of cancers: A propensity score matched cohort study in the clinical practice research datalink (CPRD).
Mackenzie IS, Thompson AM, Wei L, Morant S, MacDonald TM.
Pharmacoepidemiol Drug Saf 2014 10;23:353-354.
Design and feasibility of a study using the clinical practice research datalink general practice online database (CPRD gold) to assess the risk of new onset of auto-immune diseases (NOAD) following administration of the human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine.
Rosillon D, Willame C, Pladevall M, Zima J, Van DB, Bunge E, Van Staa T, Boggon R, Baril L.
Pharmacoepidemiol Drug Saf 2014 10;23:164-165.
Metformin and cancer risk: A cohort study in the UK Clinical Practice Research Datalink analyzed like a randomized trial.
Tsilidis KK, Capothanassi D, Allen N, Rizos E, Lopez D, Van Veldhoven K, Sacerdote C, Ashby D,
Vineis P, Tzoulaki I, Ioannidis J.
Cancer Res 2014 Oct 01;74(19).
Time trends and risk factors for hospitalisation after community-acquired pneumonia in older adults in
England
Millett, E.R.C. , De Stavola, B.L. , Quint, J.K. , Smeeth, L. , Thomas, S.L.
Thorax. 2014. 69():A10.
The impact of the publication of cardiovascular safety signals on the prescribing of varenicline: An interrupted time-series analysis
Filion, Kristian B. , Eberg, Maria , Azoulay, Laurent
Circulation. 2014. 130():.
Identifying risk factors associated with elevated blood eosinophil counts in patients with asthma from primary care clinical records
Price, D.B. , Bleecker, E.R. , Campbell, J.D. , Corrigan, C.J. , Pavord, I.D. , Rigazio, A. , Burden, A. , Von
Ziegenweidt, J. , Ashton, V.L. , Gopalan, G.H. , Buatti Small, M.
Annals of Allergy, Asthma and Immunology. 2014. 113(5):A43.
Factors associated with weight gain and hypoglycaemia and the impact upon hospitalisation in type 2 diabetes patients managed with metformin plus sulphonylurea
McEwan, P. , Gordon, J. , Evans, M. , Puelles, J.
Value in Health. 2014. 17(7):A360.
An observational cohort study of diabetes-associated secondary health care utilisation in patients with type 2 diabetes prescribed dual combination therapy with oral anti-hyperglycaemic agents in the UK
Das, R. , Langerman, H. , D'Oca, K. , Strongman, H.
Value in Health. 2014. 17(7):A360.
Antiepileptic drug (AED) treatment sequencing in the UK in patients with epilepsy: Real-life practice data using CPRD
Borghs, S. , Logan, J. , Hong, L.S. , Butt, T.
Value in Health. 2014. 17(7):A403-A404.
A database analysis of patients eligible for second-line lipid-lowering treatment for hypercholesterolaemia in
England
Amber, V. , Jameson, K. , Das, R. , Baxter, C. , Watson, L.
Value in Health. 2014. 17(7):A476-A477.
Epidemiology and severity of chronic obstructive pulmonary disease (COPD) in the United Kingdom (UK)
Raluy-Callado, M. , Lambrelli, D. , MacLachlan, S. , Merinopoulou, E. , Hagan, M.A. , Khalid, J.M.
Value in Health. 2014. 17(7):A590.
Differences in usage of clobazam vs. Clonazepam for epilepsy
Jones, Daniel , Isojarvi, Jouko , Guiraud-Diawara, Alice , Shen, Vivienne , Verpillat, Patrice
Annals of Neurology. 2014. 76():S31.
Free communications 5: Epidemiology, genetics, outcomes chronic inflammatory disorders and risk of stroke:
Population-based cohort study
Alex, D. , Chowienczyk, P. , Charlton, J. , Gulliford, M.C.
International Journal of Stroke. 2014. 9():25.
Free communications 6: Preventive strategies, public awareness quality improvement secondary prevention of stroke. implementation of a point-of-care, cluster randomized trial using electronic health records (ecrt study)
Alex, D. , Van Staa, T. , McDermott, L. , McCann, G. , Ashworth, M. , Charlton, J. , Wolfe, C.D.A. , Rudd,
A. , Yardley, L. , Gulliford, M.C.

29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
International Journal of Stroke. 2014. 9():27.
Preventive stroke strategies allopurinol and change in blood pressure in adults with hypertension
Beattie, C. , Fulton, S. , Walters, M. , Padmanabhan, S. , Dawson, J.
International Journal of Stroke. 2014. 9():276.
Abstracts of the 30th International Conference on Pharmacoepidemiology and Therapeutic Risk Management
Pharmacoepidemiology and Drug Safety. 2014. 23():.
Pattern of risks of rheumatoid arthritis among patients using statins: A cohort study with the clinical practice research datalink
De Jong, Hilda J. , Tervaert, Jan Willem Cohen , Lalmohamed, Arief , De Vries, Frank , Vandebriel, Rob J. ,
Van Loveren, Henk , Klungel, Olaf H. , Van Staa, Tjeerd
Pharmacoepidemiology and Drug Safety. 2014. 23():2.
Antiepileptic drug use before, during and after pregnancy: A study in 7 European regions
Charlton, Rachel , Garne, Ester , Wang, Hao , Klungsøyr, Kari , Jordan, Sue , Neville, Amanda , Pierini,
Anna , Hansen, Anne Vinkle , Engeland, Anders , Gini, Rosa , Thayer, Daniel , Tingay, Karen , Bos, H. Jens ,
Puccini, Aurora , Andersen, Anne Marie Nybo , Dolk, Helen , De Jong-Van Den Berg, Lolkje
Pharmacoepidemiology and Drug Safety. 2014. 23():22-23.
Evaluating different physician's prescribing preference based instrumental variables in the study of beta2-agonist use and the risk of acute myocardial infarction
Uddin, Md Jamal , Groenwold, Rolf H.H. , De Boer, Anthonius , Afonso, Ana , Primatesta, Paola , Becker,
Claudia , Belitser, Svetlana V. , Hoes, Arno W. , Roes, Kit C.B. , Klungel, Olaf H.
Pharmacoepidemiology and Drug Safety. 2014. 23():32.
Rates of opportunistic infections in psoriatic arthritis patients compared to non-psoriatic arthritis patients
Hagberg, Katrina W. , Li, Lin , Peng, Michael M. , Jick, Susan
Pharmacoepidemiology and Drug Safety. 2014. 23():49.
The risk of major and any (non-hip) fracture after hip fracture in the United Kingdom: 2000-2010
Klop, Corinne , Gibson-Smith, Deborah , Elders, Petra J.M. , Van Schoor, Natasja , Welsing, Paco M.J. ,
Leufkens, Hubert G.M. , Harvey, Nicholas C. , Van Staa, Tjeerd P. , De Vries, Frank
Pharmacoepidemiology and Drug Safety. 2014. 23():86-87.
Use of psychotropic medication for people with learning disability or autism in England: A descriptive study using the clinical practice research datalink
Boggon, Rachael , Glover, Gyles , Ridge, Keith , Avery, Ray
Pharmacoepidemiology and Drug Safety. 2014. 23():89-90.
Regional variation in strong opioid prescribing in UK primary care settings
Adan, Muna , Chen, Li-Chia , Knaggs, Roger
Pharmacoepidemiology and Drug Safety. 2014. 23():115.
The risk of colorectal cancer in patients with type 2 diabetes: Associations with treatment stage and obesity
Peeters, Paulus J.H.L. , Bazelier, Marloes T. , Leufkens, Hubert G.M. , De Vries, Frank , De Bruin, Marie L.
Pharmacoepidemiology and Drug Safety. 2014. 23():169.
Mortality in British hip fracture patients, 2000-2010: A population-based retrospective cohort study
Klop, Corinne , Welsing, Paco M.J. , Cooper, Cyrus , Harvey, Nicholas C. , Bijlsma, Johannes W.J. , Elders,
Petra J.M. , Leufkens, Hubert G.M. , De Vries, Frank
Pharmacoepidemiology and Drug Safety. 2014. 23():180.
Comparator choice in diabetes drug studies: Single class or non-user comparator group?
Brodovicz, Kimberly G. , Ritchey, Mary E. , Chen, Yong , Senderak, Michael , Liao, Jane , Girman, Cynthia
J. , Shankar, Ravi , Liu, Zhiwen , Engel, Samuel S.
Pharmacoepidemiology and Drug Safety. 2014. 23():183.
Risk of out-of-hospital sudden cardiac death with use of domperidone, proton pump inhibitors, and metoclopramide
Arana, Alejandro , Johannes, Catherine , Varas, Cristina , Rothman, Kenneth J. , McQuay, Lisa J. , Yang,
Qing , Fife, Daniel
Pharmacoepidemiology and Drug Safety. 2014. 23():189.
Identification of prediabetes, healthcare utilization and progression to diabetes in CPRD
Hong, Jin-Liern , McNeill, Ann Marie , He, Jinghua , Brodovicz., Kimberly
Pharmacoepidemiology and Drug Safety. 2014. 23():194.
Monitoring for proteinuria in patients with type 2 diabetes mellitus in the U.K. clinical practice research datalink
Dolin, Paul , Liang, Huifang , Vallarino, Carlos , Manne, Sudhakar
Pharmacoepidemiology and Drug Safety. 2014. 23():195.
Characteristics of patients with type 2 diabetes starting sitagliptin vs. other oral diabetes medications and

45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
56.
57.
58.
59. propensity score balance
Brodovicz, Kimberly G. , Ritchey, Mary E. , Chen, Yong , Senderak, Michael , Liao, Jane , Engel, Samuel S.
, Shankar, Ravi , Liu, Zhiwen , Girman, Cynthia J.
Pharmacoepidemiology and Drug Safety. 2014. 23():195-196.
Baseline characteristics of patients with type 2 diabetes initiating sitagliptin or GLP-1 receptor agonists
Brodovicz, Kimberly G. , Ritchey, Mary E. , Chen, Yong , Senderak, Michael , Liao, Jane , Girman, Cynthia
J. , Shankar, Ravi , Liu, Zhiwen , Engel, Samuel S.
Pharmacoepidemiology and Drug Safety. 2014. 23():196.
Assessment of prediabetes in the United Kindgom CPRD and its association with incident cancers
Hong, Jin-Liern , McNeill, Ann Marie , He, Jinghua , Brodovicz, Kimberly
Pharmacoepidemiology and Drug Safety. 2014. 23():202-203.
Application of targeted maximum likelihood estimation in pharmacoepidemiology
Pang, Menglan , Schuster, Tibor , Filion, Kristian B. , Eberg, Maria , Platt, Robert W.
Pharmacoepidemiology and Drug Safety. 2014. 23():207-208.
Are ECG monitoring recommendations before prescription of QT prolonging drugs applied in daily practice?
The example of haloperidol
Warnier, Miriam , Rutten, Frans , Souverein, Patrick , Hoes, Arno , De Boer, Anthonius , De Bruin, Marie
Pharmacoepidemiology and Drug Safety. 2014. 23():228-229.
Effect of conventional enzyme-inducing antiepileptic drugs on cancer mortality and survival: An exposedunexposed study of carcinoma breast and glioblastoma multiforme
Singh, Gagandeep , Sander, Ley , Bell, Gail
Pharmacoepidemiology and Drug Safety. 2014. 23():249-250.
A propensity score matched cohort study to measure the effects of orlistat or bariatric surgery on health outcomes in a general uk population sample
Douglas, Ian J. , Bhaskaran, Krishnan , Batterham, Rachel L. , Smeeth., Liam
Pharmacoepidemiology and Drug Safety. 2014. 23():262-263.
Creating a pregnancy register for auk population
Boggon, Rachael , Williams, Tim
Pharmacoepidemiology and Drug Safety. 2014. 23():314.
Factors associated with patients' adherence to antihypertensive drug classes in the uk
Baker, Amanj , Chen, Li-Chia , Elliott, Rachel
Pharmacoepidemiology and Drug Safety. 2014. 23():320.
Effect of long-term aspirin use on the risk for neovascular age-related macular degeneration
Duijnhoven, Ruben G. , Van Leeuwen, Redmer , Straus, Sabine M. , Imhof, Saskia M. , Hoes, Arno W. , De
Boer, Anthonius , De Bruin, Marie L.
Pharmacoepidemiology and Drug Safety. 2014. 23():323.
Glitazone antidiabetics and the risk of parkinson's disease
Brauer, Ruth , Bhaskaran, Krishnan , Chaturvedi, Nishi , Dexter, David , Smeeth, Liam , Douglas, Ian
Pharmacoepidemiology and Drug Safety. 2014. 23():336.
Postmarketing evaluation of the safety of saxagliptin: An interim analysis
Haynes, Kevin , Nezamzadeh, Melissa S. , Newcomb, Craig W. , Roy, Jason , Kite, Whitney , Carbonari,
Dena M. , Hennessy, Sean , Cardillo, Serena , Freeman, Cristin P. , Holick, Crystal N. , Esposito, Daina B. ,
Tjeerd, Van Staa , Harshvinder, Bhullar , Strom, Brian L. , Vincent, Lo Re
Pharmacoepidemiology and Drug Safety. 2014. 23():336-337.
Calcium channel blockers and cancer risk using the UK CPRD
Grimaldi-Bensouda, Lamiae , De Groot, Mark , Reynolds, Robert , Klungel, Olaf , Rossignol, Michel
Pharmacoepidemiology and Drug Safety. 2014. 23():353.
Safety of seasonal influenza vaccination in solid organ transplant recipients
Dos Santos, Gaël , Haguinet, Franc¸ois , Ferreira, Germano L.C. , Webb, Dave , Logie, John , Rosillon,
Dominique , Shinde, Vivek , Cohet, Catherine
Pharmacoepidemiology and Drug Safety. 2014. 23():357-358.
Comparison of atria and CHA2DS2-vasc risk stratification schemes for the prediction of stroke in the individual patient with atrial fibrillation and the impact on treatment decisions
Van Den Ham, Hendrika A. , Klungel, Olaf H. , Singer, Daniel E. , Leufkens, Hubert G.M. , Van Staa, Tjeerd
P.
Pharmacoepidemiology and Drug Safety. 2014. 23():359-360.
The risk of acute liver injury among users of antibiotic medications in the protect project: The results of a nested case-control study using european outpatient healthcare data
Brauer, Ruth , Douglas, Ian , Rodriguez, Luis Alberto Garcia , Bate, Andrew , Smeeth, Liam , Reynolds,
Robert , Klungel, Olaf , Ruigomez, Ana

60.
61.
62.
63.
64.
65.
66.
67.
68.
69.
70.
71.
72.
73.
Pharmacoepidemiology and Drug Safety. 2014. 23():372-373.
Evaluation of “pre-treated” bipolar disorder patients receiving atypical antipsychotics in the UK using an electronic health record database
Yong, Mellissa , Liao, Jane , Besson, Herve , Lui, Zhiwen , Jay, Pearson
Pharmacoepidemiology and Drug Safety. 2014. 23():385-386.
Safety of glaxosmithkline's inactivated adjuvanted (AS03) a/H1N1PDM09 pandemic influenza vaccine in solid organ transplant recipients
Cohet, Catherine , Haguinet, Franc¸ois , Ferreira, Germano L.C. , Webb, Dave , Logie, John , Rosillon,
Dominique , Shinde, Vivek , Dos Santos, Gaël
Pharmacoepidemiology and Drug Safety. 2014. 23():387-388.
Risk of mortality withvenous thromboembolism in CPRD gold: The impact of using linked data
Gallagher, Arlene M. , Williams, Tim , Leufkens, Hubert G.M. , De Vries, Frank
Pharmacoepidemiology and Drug Safety. 2014. 23():393-394.
Psoriasis and the risk of myocardial infarction: A population-based cohort study using the clinical practice research datalink
Parisi, Rosa , Rutter, Martin K. , Lunt, Mark , Young, Helen S. , Symmons, Deborah P.M. , Griffiths,
Christopher E.M. , Ashcroft, Darren M.
Pharmacoepidemiology and Drug Safety. 2014. 23():444.
Rates of cardiovascular disease and major adverse cardiovascular events in psoriatic arthritis patients compared to non-psoriatic arthritis patients
Li, Lin , Hagberg, Katrina W. , Peng, Michael M. , Jick, Susan
Pharmacoepidemiology and Drug Safety. 2014. 23():448.
Risk of spontaneous abortion in young women exposed to human papillomavirus (HPV)-16/18 AS04adjuvanted vaccine in the united kingdom: An observational cohort study
Baril, Laurence , Rosillon, Dominique , Willame, Corinne , Angelo, Maria-Genalin , Zima, Julia , Van Den
Bosch, Judith H. , Van Staa, Tjeerd , Boggon, Rachel , Bunge, Eveline , Hernandez-Diaz, Sonia , Chambers,
Christina
Pharmacoepidemiology and Drug Safety. 2014. 23():491.
Identifying novel factors beyond prior hospitalisations, including biomarkers, associated with future asthma hospitalisation risk from routine UK primary care clinical records
Price, D.B. , Bleecker, E.R. , Campbell, J.D. , Corrigan, C.J. , Pavord, I.D. , Wenzel, S.E. , Thomas, M. ,
Wilson, A.M. , Clark, A. , Rigazio, A. , Burden, A. , Ashton, V.L. , Gopalan, G.H. , Buatti Small, M.
Allergy: European Journal of Allergy and Clinical Immunology. 2014. 69():61.
Factors associated with weight gain and hypoglycaemia and the impact upon hospitalisation in type 2 diabetes patients managed with metformin plus sulfonylurea
Gordon, J. , McEwan, P. , Evans, M. , Puelles, J.
Diabetologia. 2014. 57(1):S142.
Lower respiratory tract infections and the use of dipeptidyl peptidase-4 inhibitors: A population-based matched cohort study
Faillie, J.-L. , Azoulay, L. , Filion, K. , Patenaude, V. , Suissa, S. , Ernst, P.
Diabetologia. 2014. 57(1):S363.
Potentially harmful prescribing in older UK Patients: What drugs matter?
Ble, A. , Masoli, J.A.H. , Barry, H.E. , Winder, R.E. , Tavakoly, B. , Henley, W.E. , Valderas, J. , Melzer, D. ,
Richards, S.H.
European Geriatric Medicine. 2014. 5():S216-S217.
Oral anticoagulant use but not antiplatelet reduces stroke and mortality in patients with asymptomatic ambulatory atrial fibrillation
Freedman, S.B. , Martinez, C. , Wallenhorst, C. , Katholing, A.
European Heart Journal. 2014. 35():726.
Cost-effectiveness analysis of screening for atrial fibrillation in pharmacies using an iPhone handheld ECG
(SEARCH-AF)
Lowres, N. , Salkeld, G. , Neubeck, L. , Martinez, C. , Wallenhorst, C. , Freedman, S.B.
European Heart Journal. 2014. 35():1032.
Comparison of ATRIA and CHA2DS2-VASc risk stratification schemes for the prediction of stroke in the individual patient with atrial fibrillation and the impact on treatment decisions
Van Den Ham, H.A. , Klungel, O.H. , Singer, D.E. , Leufkens, H.G.M. , Van Staa, T.P.
European Heart Journal. 2014. 35():1032.
Risk of stroke following herpes zoster: A self-controlled case-series study
Langan, S. , Minassian, C. , Smeeth, L. , Thomas, S.
Journal of Investigative Dermatology. 2014. 134():S39.

74.
75.
76.
77.
78.
79.
80.
81.
82.
83.
84.
85.
86.
87.
88.
89.
Prophylactic impact of bariatric surgery on the development of diabetes in a population-based cohort
Khan, O. , Booth, H. , Reddy, M. , Prevost, T. , Charlton, J. , Littlejohns, P. , Ashworth, M. , Dregan, A. ,
Gulliford, M.C.
Obesity Surgery. 2014. 24(8):1147-1148.
Impact of bariatric surgery on diabetes treatment and control during 6 years follow-up in a population-based cohort
Reddy, M. , Booth, H. , Khan, O. , Prevost, T. , Charlton, J. , Littlejohns, P. , Ashworth, M. , Dregan, A. ,
Gulliford, M.C.
Obesity Surgery. 2014. 24(8):1235-1236.
Excess costs associated with possible misdiagnosis of Alzheimer's disease among patients with vascular dementia in a UK CPRD population
Happich, Michael , Kirson, Noam Y. , Desai, Urvi , King, Sarah , Birnbaum, Howard G. , Price, David ,
Belger, Mark , Hunter, Craig A. , Lenox-Smith, Alan J. , Reed, Catherine C.
Alzheimer's and Dementia. 2014. 10():P911-P912.
Variation in the risk of venous thromboembolism in patients following colectomy: A population based cohort study from England
Humes, D. , Walker, A. , Hunt, B. , West, J.
Colorectal Disease. 2014. 16():15.
Medical and surgical intervention following a diagnosis of ulcerative colitis: A population based study using linked primary and secondary care data
Humes, D. , Card, T.
Colorectal Disease. 2014. 16():53.
The epidemiology of extra-articular manifestations in ankylosing spondylitis: A population-based matched cohort study
Stolwijk, C. , Essers, I. , Van Tubergen, A. , Boonen, A. , Bazelier, M. , De Bruin, M. , De Vries, F.
Annals of the Rheumatic Diseases. 2014. 73():.
Performance of the framingham cardiovascular risk prediction model with and without CRP in RA patients:
Analysis of UK clinical practice research data
Cawston, H. , Alemao, E. , Bourhis, F. , Hines, P. , Le, T. , Al, M. , Rutten-van Molken, M. , Solomon, D.
Annals of the Rheumatic Diseases. 2014. 73():.
Cardiovascular morbidity in patients with ankylosing spondylitis: A population-based cohort study
Essers, I. , Stolwijk, C. , Van Tubergen, A. , Boonen, A. , De Bruin, M.L. , Bazelier, M. , De Vries, F.
Annals of the Rheumatic Diseases. 2014. 73():.
Eligibility for urate-lowering treatment around the time of diagnosis in gout patients: A nationwide population study
Kuo, C.-F. , Grainge, M.J. , Mallen, C. , Zhang, W. , Doherty, M.
Annals of the Rheumatic Diseases. 2014. 73():.
Longitudinal profiles of blood pressure, lipids and HbA1c, and their association with vascular and mortality risks in patients with T2DM under cardioprotective medications
Paul, Sanjoy , Kleine, Kere , Majeed, Azeem , Khunti, Kamlesh
Diabetes. 2014. 63():A347.
Differences in usage of clobazam vs. Clonazepam for epilepsy
Isojarvi, J. , Jones, D. , Guiraud-Diawara, A. , Shen, V. , Verpillat, P.
Epilepsia. 2014. 55():114.
Resource use associated with hepatic encephalopathy in patients with severe liver disease
Orr, J. , Morgan, C.L. , Hudson, M. , Jenkins-Jones, S. , Conway, P. , Radwan, A. , Currie, C.J.
Gut. 2014. 63():A94-A95.
Mortality associated with hepatic encephalopathy in patients with severe liver disease
Morgan, C.L. , Jenkins-Jones, S. , Radwan, A. , Conway, P. , Currie, C.J.
Gut. 2014. 63():A94.
Predictors of colectomy and the impact of thiopurines on the risk of colectomy in ulcerative colitis - A national UK based observational study
Chhaya, V. , Saxena, S. , Cecil, E. , Chatu, S. , Subramanian, V. , Curcin, V. , Majeed, A. , Pollok, R.
Gut. 2014. 63():A176-A177.
Have perianal surgery rates decreased with the rise in thiopurine use in Crohn's disease?
Chhaya, V. , Saxena, S. , Cecil, E. , Subramanian, V. , Curcin, V. , Majeed, A. , Pollok, R.
Gut. 2014. 63():A176.
Oral statin use associated with reduced risk of monoclonal gammopathy of undetermined significance and multiple myeloma: A population based nested case-control study
Mcshane, C. , Tapper, C. , Murray, L.J. , Landgren, O. , Bradley, M. , Hughes, C. , Anderson, L.A.

90.
91.
92.
93.
94.
95.
96.
97.
98.
99.
100.
101.
102.
103.
104.
105.
106.
Haematologica. 2014. 99():356.
How have PID rates changed during the era of chlamydia screening in England? data from primary care and genitourinary medicine clinics, 1995-2012
Sile, Bersabeh , Woodhall, Sarah C. , Hughes, Gwenda , Soldan, Kate , Ross, Jonathan , Williams, Tim ,
Wetten, Sally
Sexually Transmitted Diseases. 2014. 41():S97.
Association between benzodiazepines drugs and total mortality: Evidence from a study on CPRD dat1
Palmaro, A. , Dupouy, J. , Lapeyre-Mestre, M.
Fundamental and Clinical Pharmacology. 2014. 28():59.
Rates and predictors of progression to adenocarcinoma in a large population based barrett's esophagus cohort
Iyer, Prasad G. , Borah, Bijan J. , Heien, Herbert , Chak, Amitabh
Gastroenterology. 2014. 146(5):S121-S122.
Treatment patterns with lipid-altering drugs in high-risk vascular disease in the United Kingdom
Zhao, Z. , Zhu, Y. , Collins, J. , Donaldson, R. , Engelman, W. , Nordstrom, B.
Value in Health. 2014. 17(3):A122.
Statin dosing patterns and lipid levels among patients with high-risk vascular disease
Nordstrom, B. , Collins, J. , Donaldson, R. , Engelman, W. , Zhu, Y. , Zhao, Z.
Value in Health. 2014. 17(3):A122.
Glucose-lowering with exogenous insulin monotherapy in type 2 diabetes: Dose-response association with all-cause mortality, cardiovascular events, and incident cancer
Holden, S.E. , Jenkins-Jones, S. , Morgan, C.L. , Schernthaner, G. , Currie, C.J.
Value in Health. 2014. 17(3):A240.
The impact of concomitant metformin on mortality and other serious outcomes in people with type 2 diabetes treated with insulin
Holden, S.E. , Currie, C.J.
Value in Health. 2014. 17(3):A241.
Weight change and health care resource use (HCRU) in english patients with type 2 diabetes mellitus
(T2DM) initiating a new antidiabetic drug class
Rigney, U. , Blak, B.T. , Sternhufvud, C. , Ycas, J. , Racketa, J. , Hammar, N.
Value in Health. 2014. 17(3):A252.
Estimated incidence and prevalence of neuromyelitis optica in the England from 1998 to 2011
Constantinescu, Cris , Chou, I-Jun , Kuo, Chang-Fu , Tanasescu, Radu , Whitehouse, William
Neurology. 2014. 82(10):.
Differences in usage of clobazam vs. Clonazepam for epilepsy
Jones, Daniel , Isojarvi, Jouko , Guiraud-Diawara, Alice , Shen, Vivienne , Verpillat, Patrice
Neurology. 2014. 82(10):.
Characteristics of children with asthma when treatment is stepped up-a real-life observation study of 17256 episodes
Turner, S. , Price, D. , Richardson, K. , Ali, M. , West, D.
Archives of Disease in Childhood. 2014. 99():A40.
Real-world assessment of renal involvement in tuberous sclerosis complex (TSC) patients in the United
Kingdom (UK)
Kingswood, J.C. , Demuth, D. , Nasuti, P. , Lucchese, L. , Gray, E. , Magestro, M.
European Urology, Supplements. 2014. 13(1):e318-e318a.
Mortality associated with hepatic encephalopathy in patients with severe liver disease
Morgan, C.L. , Jenkins-Jones, S. , Radwan, A. , Conway, P. , Reynolds, A. , Currie, C.J.
Journal of Hepatology. 2014. 60(1):S219.
Resource use associated with hepatic encephalopathy in patients with liver disease
Orr, J.G. , Morgan, C.L. , Jenkins-Jones, S. , Hudson, M. , Conway, P. , Radwan, A. , Currie, C.J.
Journal of Hepatology. 2014. 60(1):S228-S229.
Usage Patterns of Clobazam Vs. Clonazepam in Epilepsy: Results from the UK CPRD Database
Isojarvi, Jouko , Cossecq, M. , Guiraud-Diawara, A. , Jones, Daniel , Shen, V. , Verpillat, P.
Neurosciences. 2014. 19(2):158.
Primary care costs attributable to osteoarthritis before total hip replacement
Pinedo-Villanueva, R. , Turner, D. , Raftery, J.P. , Cooper, C. , Arden, N.K.
Osteoarthritis and Cartilage. 2014. 22():S210-S211.
UK temporal trends for time from diagnosis of hip/knee osteoarthritis to joint replacement
Culliford, D.J. , Judge, A. , Prieto-Alhambra, D. , Cooper, C. , Arden, N.K.
Osteoarthritis and Cartilage. 2014. 22():S213.

107.
108.
109.
110,
111.
112.
113.
114.
115.
116.
Mortality in british hip fracture patients, 2000-2010: A population-based retrospective cohort study
DeVries, F. , Leufkens, H.G.M. , Bijlsma, J. , Elders, P. , Harvey, N.C. , Cooper, C. , Welsing, P. , Klop, C.
Osteoporosis International. 2014. 25():S170.
Negative rheumatoid factor in primary care delays referral of patients with rheumatoid arthritis
Miller, Anne , Nightingale, Alison L. , Sammon, Cormac J. , Mahtani, Kamal R. , Holt, Tim , McHugh, Neil ,
De Vries, Corinne S. , Luqmani, Raashid A.
Rheumatology (United Kingdom). 2014. 53():i29.
Varenicline and the risk of adverse cardiovascular events: A population-based cohort study
Filion, Kristian B. , Dell'Aniello, Sophie , Eberg, Maria , Renoux, Christel , Daskalopoulou, Stella S. , Suissa,
Samy
Circulation. 2014. 129():.
Impact of UK guidelines on clinical prescribing in patients with Type 2 diabetes: A comparative effectiveness analysis of liraglutide vs sitagliptin in the UK
McEwan, P. , Evans, M.L. , Nyeland, M.E. , Skovgaard, R. , Richards, A. , Bergan, E.Q. , Demuth, D. ,
Alvarez, L Garcia , Muthutantri, A. , Ploug, U.J.
Diabetic Medicine. 2014. 31():174.
Risk of acute appendicitis in and around pregnancy: A population-based cohort from England
Zingone, F. , Abdul Sultan, A. , Humes, D. , West, J.
Digestive and Liver Disease. 2014. 46():S132.
Comparison of rates of prescribing oral corticosteroids for asthma exacerbations between step-down therapy approaches among initiators of inhaled corticosteroids and long-acting beta-agonist combination therapy
Ali, Ayad K. , Winterstein, Almut , Hendeles, Leslie , Lu, Xiaomin , Segal, Richard , Hartzema, Abraham
Journal of Allergy and Clinical Immunology. 2014. 133(2):AB177.
Adolescent and young adults are more likely to require total colectomy in ulcerative colitis: UK population based cohort study
Chhaya, V. , Pollok, R. , Cecil, E. , Majeed, A. , Saxena, S.
Journal of Crohn's and Colitis. 2014. 8():S33.
Increasing colectomy rates over time in ulcerative colitis and the impact of thiopurines: A nationwide cohort study
Chhaya, V. , Saxena, S. , Cecil, E. , Majeed, A. , Pollok, R.
Journal of Crohn's and Colitis. 2014. 8():S53-S54.
Usage patterns of clobazam VS. clonazepam in epilepsy: Results from the UK CPRD database
Isojarvi, Jouko , Cossecq, M. , Guiraud-Diawara, A. , Jones, Daniel , Shen, V. , Verpillat, P.
Epilepsy Currents. 2014. 14():212.
Diagnosis and treatment patterns in the clinical practice research datalink (CPRD): A population study of men with hypogonadism with and without type 2 diabetes who initiated treatment with testosterone replacement therapy
Shortridge, E. , Lanes, S. , Polzer, P. , Wentworth, C. , Razzoli, E. , Gawlik, M. , Schuster, D. , Matfin, G.
Journal of Sexual Medicine. 2014. 11():6.
1.
2.
3.
An exploratory study using General Practice Research Database to compare recognition of palliative care needs for patients with heart failure compared with those with cancer
Amy Gadoud, Eleanor Kane, Una Macleod, Miriam Johnson.
Society for Academic Primary Care, July 2013
Socio-economic position and childhood multimorbidity: a study using linkage between the Avon
Longitudinal Study of Parents and Children and the General Practice Research Database
Rosie Cornish, Andrew Boyd, Tjeerd Van Staa, Chris Salisbury, John Macleod.
Society for Academic Primary Care, July 2013
Incidence and management of Bell’s palsy in the UK: segmented time series regression analysis of treatment from 2001 to 2012
Daniel Morales, Fergus Daly, Peter Donnan, Tjeerd van Staa, Frank Sullivan.

4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
Society for Academic Primary Care, July 2013
Modelling conditions in the Primary Care Databases: an application to Severe Mental Illness with the
Clinical Practice Research Datalink
Ivan Olier, David Springate, David Reeves, Siobhan Reilly, Tim Doran, Evangelos Kontopantelis.
Society for Academic Primary Care, July 2013
Exposure to bisphosphonates and risk of common non-gastrointestinal cancers: series of nested casecontrol studies using QResearch and CPRD data
Yana Vinogradova, Carol Coupland, Julia Hippisley-Cox
Society for Academic Primary Care, July 2013
Prevalence and Incidence of Idiopathic Pulmonary Fibrosis in UK Healthcare Databases, GPRD and
THIN; Need for an IPF Registry
Paula L Thompson, Stephanie Chretin, Francoise Bugnard, William C Maier, Rory Cameron, Mark Fisher,
Christophe Giot, Christian Hill, Imran Kausar.
Pharmacoepidemiology and Drug Safety, August 2013
Is Childhood Attention-Deficit (Hyperactivity) Disorder Associated with Atopic Diseases and Skin
Infections? A Matched Case-Control Study Using the GPRD
Eelko Hak, Tjalling W De Vries, Pieter J Hoekstra, Susan S Jick.
Pharmacoepidemiology and Drug Safety, August 2013
The Identification of Incident Cancers in UK Primary Care Databases: A Systematic Review
Michael E Rañ opa, Ian Douglas, Tjeerd van Staa, Liam Smeeth, Krishnan Bhaskaran.
Pharmacoepidemiology and Drug Safety, August 2013
Congenital Malformations in the Offspring of Women with Asthma
Rachel Charlton, Julia Snowball, Kourtney Davis, Corinne de Vries.
Pharmacoepidemiology and Drug Safety, August 2013
Calcium Channel Blockers and Esophageal Cancer: A Case-Control Analysis
Claudia Becker, Susan S Jick, Christoph R Meier.
Pharmacoepidemiology and Drug Safety, August 2013
Case-Control Analysis on Metformin and Cancer of the Esophagus
Claudia Becker, Christoph R Meier, Susan S Jick, Michael Bodmer.
Pharmacoepidemiology and Drug Safety, August 2013
The Opportunities and Challenges of Delivering the Quetiapine Post-Authorization Safety Studies
(PASS); a Diverse Program of Work
Robert S Brody, Leigh Jefferies, Sherry Liu, Charles L Liss, Phil Damstetter, Lei Chen, Raj Tummala,
Dhaval G Desai.
Pharmacoepidemiology and Drug Safety, August 2013
Diabetes and the Risk of Incident Gout
Saskia G Bruderer, Michael Bodmer, Susan S Jick, Christoph R Meier.
Pharmacoepidemiology and Drug Safety, August 2013
Risk of Fracture with Thiazolidinediones: An Individual Patient Data Meta-Analysis
Marloes T Bazelier, Frank de Vries, Peter Vestergaard, Ron MC Herings, Arlene M Gallagher, Hubert GM
Leufkens, Tjeerd-Pieter van Staa.
Pharmacoepidemiology and Drug Safety, August 2013
Is the CPRD GOLD Population Comparable to the U.K. Population?
Jennifer Campbell, Daniel J Dedman, Susan C Eaton, Arlene M Gallagher, Tim J Williams.
Pharmacoepidemiology and Drug Safety, August 2013
Validation of Stroke in the Clinical Practice Research Datalink (CPRD)
Esther H Zhou, Kate Gelperin, David J Graham, Yulan Ding, Mark Levenson, Martin Rose, Shannin F

17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
Davillier, Tarek A Hammad.
Pharmacoepidemiology and Drug Safety, August 2013
Design and Feasibility of a Study Using the Clinical Practice Research Datalink General Practice
OnLine Database (CPRD GOLD) To Assess the Risk of Spontaneous Abortion (SA) Following
Administration of the Human Papillomavirus (HPV)-16/18 AS04-Adjuvanted Vaccine
Dominique Rosillon, Corinne Willame, John Logie, Sylvia Taylor, Vincent Bauchau, Maria-Genalin Angelo,
Julia Zima, Judith van den Bosch, Tjeerd van Staa, Rachael Boggon, Christina Chambers, Sonia Hernandez-
Diaz, Laurence Baril.
Pharmacoepidemiology and Drug Safety, August 2013
Risk of Seizures among Patients with Schizophrenia as Compared to the General Population in the
Clinical Practice Research Datalink (CPRD)
Meghan Jones, Jonathan Swain, Frank DeLisle, Ludmila Kryzhanovskaya, Bruce J Kinon.
Pharmacoepidemiology and Drug Safety, August 2013
Developing Acute Coronary Syndrome Disease Cohorts Using Primary and Secondary Care Database
Linkages
Robert N Lubwama, Cathy A Pinto.
Pharmacoepidemiology and Drug Safety, August 2013
Utilisation Patterns of Inhaled Corticosteroids in Patients with Asthma: A Study Using the UK Clinical
Practice Research Datalink (CPRD)
Alison L Nightingale, Julia Snowball, Rachel A Charlton, Corinne S de Vries.
Pharmacoepidemiology and Drug Safety, August 2013
TrialViz: A Feasibility Tool Based upon the CPRD GOLD Primary Care Database
Tim Williams, Shivani Puri, Joss Wickson, Rosemary Tate, Natalia Beloff, Tjeerd van Staa, Adrian Bleach,
John Cuthbert.
Pharmacoepidemiology and Drug Safety, August 2013
The Prescribing of Simvastatin in the UK - A Drug Utilisation Study in the Clinical Practice Research
Datalink (CPRD)
Craig Allen, Katherine L Donegan, Andrew Thomson.
Pharmacoepidemiology and Drug Safety, August 2013
Incidence of Food-Induced Anaphylaxis; a Retrospective Population Cohort Study in the UK Clinical
Practice Research Datalink (CPRD)
Estel Plana, Cristina Rebordosa, Ying Zhu.
Pharmacoepidemiology and Drug Safety, August 2013
Is the CPRD GOLD Population Comparable to the U.K. Population?
Jennifer Campbell, Daniel J Dedman, Susan C Eaton, Arlene M Gallagher, Tim J Williams.
Pharmacoepidemiology and Drug Safety, August 2013
Defining a Denominator Population for Linked Datasets
Shivani Puri, Tim Williams, Susan Eaton.
Pharmacoepidemiology and Drug Safety, August 2013
Drug Use Pattern of Rivaroxaban in the UK
Carlos Martinez, Stephan Rietbrock, Kiliana Suzart-Woischnik, Mari-Ann Wallander.
Pharmacoepidemiology and Drug Safety, August 2013
Risk of Fracture with Thiazolidinediones: An Individual Patient Data Meta-Analysis
Marloes T Bazelier, Frank de Vries, Peter Vestergaard, Ron MC Herings, Arlene M Gallagher, Hubert GM
Leufkens, Tjeerd-Pieter van Staa.
Pharmacoepidemiology and Drug Safety, August 2013
Test Data in General Practice Are Not Missing at Random – Can We Identify When They Are?

29.
30.
31.
32.
33.
34.
35.
36.
37.
Cormac J Sammon, Alison L Nightingale, Anne Miller, Kamal R Mahtani, Tim A Holt, Neil McHugh,
Raashid A Luqmani, Corinne S de Vries.
Pharmacoepidemiology and Drug Safety, August 2013
Trends in Incidence Rates (IR) of Hip/Femur Fractures in 5 European Countries: A Comparison Using
Electronic Health Care Records (e-HCR)
Gema Requena, Victoria Abbing-Karahagopian, Consuelo Huerta, Marieke L De Bruin, Yolanda Alvarez,
Montserrat Miret, Ulrik Hesse, Helga Gardarsdottir, Patrick Souverein, Jim Slattery, Cornelia Schneider,
Marietta Rottenkolber, Sven Schmiedl, Miguel Gil, Mark CH De Groot, Andrew Bate, Ana Ruigó mez, Luis
A Garcí a, Saga Johanson, Frank De Vries, Dolores Montero, Raymond Schlienger, Robert Reynolds, Olaf H
Klungel, Francisco J De Abajo.
Pharmacoepidemiology and Drug Safety, August 2013
Harmonization of Outcome Extraction for Heart Failure across Data Sources in the SAFEGUARD
Project
Lorenza Scotti, Andrea Arfè Antonella Zambon, Silvana Romio, Niklas Schmedt, Giorgia De Berardis,
Cormac Sammon, Miguel Gil, Elisa Martin, Gema Requena, Corine de Vries, John D Seeger, Giampiero
Mazzaglia, Irene Bezemer, Cristina Varas-Lorenzo, Mark Smits, Peter Rijnbeek, Miriam Sturkenboom,
Giovanni Corrao.
Pharmacoepidemiology and Drug Safety, August 2013
Incidence of Colorectal Cancer in Association with Diagnosed Hypertension
Estel Plana, Ying Zhu, Christoph R Meier, Raymond G Schlienger.
Pharmacoepidemiology and Drug Safety, August 2013
Harmonization of Outcome Extraction for Ischemic and Hemorrhagic Stroke across Data Sources in the SAFEGUARD Project
Niklas Schmedt, Miguel Gil, Elisa Martin, Gema Requena, Irene Bezemer, Giorgia De Berardis, Corine de
Vries, Ingrid Leal, Gwen Masclee, Giampiero Mazzaglia, Peter Rijnbeek, Silvana Romio, Cormac Sammon,
Lorenza Scotti, John Seeger, Mark Smits, Tania Schink, Christina Varas-Lorenzo, Miriam Sturkenboom,
Edeltraut Garbe.
Pharmacoepidemiology and Drug Safety, August 2013
Factors Associated with Utilization of Saxagliptin in the US and UK
Melissa S Nezamzadeh, Kevin Haynes, Dena M Carbonari, Craig Newcomb, Jason Roy, Serena Cardillo,
Kimberly BF Leidl, Jennifer Wood Ives, Stephanie DeVore, Laura Horne, Betina Blak, Daina Esposito,
Crystal Holick, Tjeerd Van Staa, Harshvinder Bhullar, Brian L Strom, Vincent Lo Re III, Eileen E Ming,
Sean Hennessy, Peter P Reese, K Rajender Reddy, David Margolis, Andrea Apter, Stephen E Kimmel,
Cristin P Freeman, Hanieh Razzaghi.
Pharmacoepidemiology and Drug Safety, August 2013
Use of Glucagon-Like Peptide 1 Analogues and the Risk of Fracture in Type 2 Diabetes Patients
Johanna HM Driessen, Hein A van Onzenoort, Arief Lalmohamed, Corinne Klop, Marloes Bazelier, Kees
Neef, Frank de Vries.
Pharmacoepidemiology and Drug Safety, August 2013
Parkinson's Disease and Risk of Retinal Degeneration
Joan Fortuny, Estel Plana.
Pharmacoepidemiology and Drug Safety, August 2013
Transparency in Data Preparation for Drug Exposure Using the Clinical Practice Research Datalink and Sensitivity of Results to Various Assumptions
Mohammad Movahedi, Mark Lunt, Therese Sheppard, Robyn Tamblyn, Nadyne Girard, Will Dixon.
Pharmacoepidemiology and Drug Safety, August 2013
Improving Consistency in Findings from Pharmacoepidemiological Studies: The IMI-PROTECT
(Pharmacoepidemiological Research on Outcomes of Therapeutics by a European ConsorTium)
Project
Mark CH de Groot, Raymond Schlienger, Robert Reynolds, Helga Gardarsdottir, Juhaeri Juhaeri, Ulrik
Hesse, Christiane Gasse, Marietta Rottenkolber, Markus Schuerch, Xavier Kurz, Olaf H Klungel.

38.
39.
40.
41.
42.
43.
44.
45.
46.
Pharmacoepidemiology and Drug Safety, August 2013
Male Breast Cancer in Users of Finasteride and Dutasteride: A Case-Control Study
Ruben G Duijnhoven, Sabine MJM Straus, Patrick C Souverein, Anthonius de Boer, Arno W Hoes, Marie L
De Bruin.
Pharmacoepidemiology and Drug Safety, August 2013
Balancing Individual Benefits and Risks of Warfarin in Patients with Atrial Fibrillation
Rianne van den Ham, Olaf H Klungel, Hubert GM Leufkens, Tjeerd P van Staa.
Pharmacoepidemiology and Drug Safety, August 2013
Total Mortality Rates across Multiple Databases: Benchmarking Results from a Distributed Data
Network - The SAFEGUARD Project
John D Seeger, Silvana Romio, Cristina Varas-Lorenzo, Lorenza Scotti, Andrea Arfè Antonella Zambon,
Miguel Gil, Gema Requena, Irene Bezemer, Georgia De Berardis, Corinne DeVries, Ingrid Leal, Gwen
Masclee, Gianluca Trifiró Peter Rijnbeek, Cormac Sammon, Niklas Schmedt, Mark Smits, Giovanni Corrao,
Miriam Sturkenboom.
Pharmacoepidemiology and Drug Safety, August 2013
Comparison of Seven Electronic Healthcare Databases in EU Countries Using a Standardized
Methodology; a Descriptive Study on the Exposure to Calcium-Channel Blockers (CCBs)
Mark CH de Groot, Rianne Van den Ham, Marieke De Bruin, Consuelo Huerta Alvarez, Miguel Gill, Ana
Afonso, Gema Requena, Ulrik Hesse, Pernille Falberg Rø nn, Patrick C Souverein, Yolanda Alvarez, Jim
Slattery, Marietta Rottenkolber, Sven Schmiedl, Liset Van Dijk, Raymond G Schlienger, Robert Reynolds,
Olaf H Klungel, Lamiae Grimaldi-Bensouda.
Pharmacoepidemiology and Drug Safety, August 2013
Antiepileptic Drug Use in Seven Electronic Health Record Databases in Europe: A Methodological
Comparison
Mark CH De Groot, Markus Schuerch, Frank De Vries, Ulrik Hesse, Belé n Oliva, Consuelo Huerta Alvarez,
Miguel Gil, Gema Requena, Francisco Abajo, Ana Afonso, Patrick C Souverein, Yolanda Alvarez, Jim
Slattery, Marietta Rottenkolber, Sven Schmiedl, Liset Van Dijk, Raymond G Schlienger, Robert Reynolds,
Olaf Klungel.
Pharmacoepidemiology and Drug Safety, August 2013
Comparison of Six Electronic Healthcare Databases in Europe Using Standardized Protocols: A
Descriptive Study on the Incidence of Cancer
Ana S Afonso, Mark CH De Groot, Rianne Van den Ham, Marie L Bruin, Consuelo Huerta Alvarez, Miguel
Gil, Ulrik Hesse, Pernille F Rø nn, Patrick C Souverein, Yolanda Alvarez, Jim Slattery, Marietta
Rottenkolber, Liset Van Dijk, Raymond G Schlienger, Robert Reynolds, Olaf H Klungel, Lamiae Grimaldi-
Bensouda.
Pharmacoepidemiology and Drug Safety, August 2013
Antidepressant Prescribing in Five European Countries: Application of Common Methods To Assess the Variation in Prevalence
V Abbing-Karahagopian, C Huerta, PC Souverein, F de Abajo, HGM Leufkens, J Slattery, Y Alvarez, M
Montserrat, M Gil, U Hesse, G Requena, F de Vries, M Rottenkolber, S Schmiedl, R Reynolds, R Schlinger,
M de Groot, OH Klungel, TP van Staa, L van Dijk, ACG Egberts, H Gardarsdottir, ML De Bruin.
Pharmacoepidemiology and Drug Safety, August 2013
A Cohort Analysis To Measure the Effect of Orlistat or Bariatric Surgery on Weight and Body Mass
Index in a General UK Population Sample
Ian J Douglas, Krishnan Bhaskaran, Liam Smeeth.
Pharmacoepidemiology and Drug Safety, August 2013
Harmonization of Acute Myocardial Infarction Identification from Different Databases in the
SAFEGUARD Project
Gwen MC Masclee, Miriam CJM Sturkenboom, Ingrid A Leal, Giorgia De Berardis, Irene Bezemer, Miguel
Gil, Elisa Martí n, Gema Requena, Cormac Sammon, Niklas Schmedt, John Seeger, Lorenza Scotti, Gianluca
Trifiro, Cristina Varas-Lorenzo, Corinne de Vries, Mark Smits, Peter Rijnbeek, Silvana Romio.

47.
48.
49.
50.
51.
52.
53.
54.
55.
56.
57.
58.
Pharmacoepidemiology and Drug Safety, August 2013
Harmonization of Diagnoses for Acute Pancreatitis Identification from Different Databases in the
SAFEGUARD Project
Gwen MC Masclee, Silvana Romio, Ingrid A Leal, Giorgia De Berardis, Irene Bezemer, Miguel Gil, Elisa
Martí n, Gema Requena, Cormac Sammon, Niklas Schmedt, John Seeger, Lorenza Scotti, Gianluca Trifiro,
Cristina Varas-Lorenzo, Corinne de Vries, Mark Smits, Peter Rijnbeek, Miriam CJM Sturkenboom.
Pharmacoepidemiology and Drug Safety, August 2013
Benefits of Different Propensity Score Methods for Evaluation of Associations and Channeling Bias over Time: Pneumonia and Inhaled Corticosteroid in a COPD New User Cohort
Hoa V Le, Rachael L DiSantostefano, Tim Sampson, Chi T Truong, Kourtney J Davis.
Pharmacoepidemiology and Drug Safety, August 2013
Comparison of Covariate Selection Approaches for Propensity Score (PS) Derivation for Multiple
Health Outcomes of Interest (HOIs): An Empirical Example
Ann Marie McNeill, Cynthia J Girman, Zhiwen Liu, Robert J LoCasale, Richard Wyss, Ying Su, Til Sturmer.
Pharmacoepidemiology and Drug Safety, August 2013
Identifying Patients in Electronic Healthcare Data When No Diagnostic Codes Are Available for the
Disease of Interest: Critical Limb Ischemia Example
Jennifer Campbell, George Geroulakos, Tjeerd van Staa.
Pharmacoepidemiology and Drug Safety, August 2013
Lessons Learned from Implementation of a Prospective, Observational Cohort Study To Assess Risk of
Spontaneous Abortion (SA) Following Administration of Human Papillomavirus (HPV)-16/18 AS04-
Adjuvanted Vaccine around Conception
Christina Chambers, Diana Johnson, Ronghui Xu, Dominique Rosillon, Judith van den Bosch, Laurence
Baril, Sylvia Taylor.
Pharmacoepidemiology and Drug Safety, August 2013
Factors and Characteristics for Medication Initiation in Type 2 Diabetes Patients in the UK
Alison K Wright, Martin K Rutter, Richard Emsley, Darren M Ashcroft, Douglas Steinke.
Pharmacoepidemiology and Drug Safety, August 2013
An Epidemiological Study Examining the Risk of Malignancy in Patients with Inflammatory Bowel
Disease
Jessica C Wilson, Raoul I Furlano, Susan S Jick, Christoph R Meier.
Pharmacoepidemiology and Drug Safety, August 2013
Effervescent, Dispersible and Soluble Medications Increase Cardiovascular Events
Jacob George, Waseem Majeed, Thomas M MacDonald, Isla S Mackenzie, Li Wei.
Pharmacoepidemiology and Drug Safety, August 2013
Baseline Characteristics and Comorbidities among United Kingdom Males Prior to Testosterone
Treatment Compared to Non-Users Stratified by Body Mass Index (BMI)
Hu Li, Jonathan Swain, Karin Benoit, Nancy Ostrowski, Stephen Motsko.
Pharmacoepidemiology and Drug Safety, August 2013
Case-Control Analysis on Metformin and Cancer of the Esophagus
Claudia Becker, Christoph R Meier, Susan S Jick, Michael Bodmer.
Pharmacoepidemiology and Drug Safety, August 2013
Calcium Channel Blockers and Esophageal Cancer: A Case-Control Analysis
Claudia Becker, Susan S Jick, Christoph R Meier.
Pharmacoepidemiology and Drug Safety, August 2013
Oral Glucocorticoids and the Risk of Incident Type II Diabetes Mellitus in Patients with Rheumatoid
Arthritis, a Retrospective Cohort Study
Mohammad Movahedi, Mark Lunt, David Ray, Will Dixon.

59.
60.
61.
62.
63.
64.
65.
66.
67.
68.
69.
70.
71.
72.
73.
Pharmacoepidemiology and Drug Safety, August 2013
Physicians' prescribing preferences are a potential instrument for patients' actual prescriptions of antidepressants.
Davies, Neil; Gunnell, David; Thomas, Kyla; et al.
American Journal of Epidemiology. 2013;177:S108.
Determinants of Prescribing Inhaled Long-Acting Beta-Agonist Bronchodilators As Monotherapy to
Adults with Asthma.
Ali, Ayad K.
Journal of Allergy and Clinical Immunology. 2013;131(2):AB4.
Weight loss of ≥3% in type II diabetes patients is associated with weight change property of newly prescribed anti-diabetic medicine in anti-depressant users over a 12-month follow-up period.
Ching-Ching Lin, Jayanti Mukherjee, Hugh Kawabata, Susan Colilla, Gail Wygant.
ISPOR 16 th
Annual European Congress, 2013.
Implementation of risk minimization measures regarding the potentially increased bladder cancer risk with pioglitazone in clinical practice within the UK
Spoendlin, J. , Dolin, P. , Meier, C.R.
International Journal of Clinical Pharmacy. 2013. 35(6):1259.
Type 2 diabetes mellitus and the risk of incident gout
Bruderer, S.G. , Jick, S.S. , Bodmer, M. , Meier, C.R.
International Journal of Clinical Pharmacy. 2013. 35(6):1272-1273.
Incidence of and risk factors for severe hypoglycemia in treated type 2 diabetes mellitus patients in the
United Kingdom
Bruderer, S.G. , Jick, S.S. , Bader, G. , Schlienger, R. , Meier, C.R.
International Journal of Clinical Pharmacy. 2013. 35(6):1333-1334.
Idiopathic pulmonary fibrosis survival has not improved in the 21st century; analysis of CPRD gold primary care data
Maher, T.M. , Strongman, H. , Boggon, R. , Kausar, I.
Thorax. 2013. 68():A82-A83.
Changing face of multiple sclerosis in The United Kingdom 1990-2010. An incidence and prevalence study
Mackenzie, Isla S. , Morant, Steven V. , Bloomfield, Glenys A. , MacDonald, Thomas M. , O'Riordan,
Jonathan I.
Journal of Neurology, Neurosurgery and Psychiatry. 2013. 84(11):.
Comparative effectiveness of liraglutide versus sitagliptin in type 2 diabetes in the United Kingdom: A retrospective study in primary care
Nyeland, M.E. , Ploug, U.J. , Skovgaard, R. , Richards, A. , Bergan, E.Q. , Zammit, D.C. , Evans, M.
Value in Health. 2013. 16(7):A431.
What factors predict the decision to treat acute coronary syndrome invasively? evidence from clinical practice
Fakhouri, W.K. , Belger, M. , Larkin, L. , McCollam, P.L. , Rennie, K.L. , Donaldson, R. , Di Tanna, G.L. ,
Neasham, D.
Value in Health. 2013. 16(7):A539.
Resource utilisation and costs of total hip arthroplasty in the United Kingdom: A descriptive analysis
Raluy, M. , Burge, R. , Lambrelli, D. , MacLachlan, S. , Wu, N. , Chen, S.Y. , Schoenfeld, M.
Value in Health. 2013. 16(7):A561.
Health care resource usage, treatment and costs among patients with hip fracture in the United Kingdom
Lambrelli, D. , Burge, R. , Raluy, M. , Karlsdotter, K. , Chen, S.Y. , Wu, N. , Schoenfeld, M.
Value in Health. 2013. 16(7):A561.
Screening characteristics and diabetes biomarkers in French and UK patient-level databases
Cabrera, C. , Le Jeunne, P. , Lee, A. , Thomas, F. , Mian, N. , McDonell, A.
Value in Health. 2013. 16(7):A582.
Description of treatment pathways in chronic diseases using large general practitioner longitudinal data: The example of pharmaco-therapy in parkinson’s disease in the United Kingdom
Guelfucci, F. , Neine, M. , Bineau, S. , Milea, D. , Aballea, S.
Value in Health. 2013. 16(7):A583.
The use of European electronic health records to investigate cancer treatment pathways
Langham, J. , Langham, S. , Weir, S. , Ralston, S.
Value in Health. 2013. 16(7):A615.

74.
75.
76.
77.
78.
79.
80.
81.
82.
83.
84.
85.
86.
87.
88.
89.
Drug compliance and persistence in patients with parkinson’s disease treated in primary care in the United
Kingdom: A CPRD-based study
Bineau, S. , Guelfucci, F. , Neine, M. , Aballea, S. , Milea, D.
Value in Health. 2013. 16(7):A628-A629.
Comparing COPD costs by exacerbation frequency and dyspnoea level in a primary care setting in the
United Kingdom
Punekar, Y.S. , Shukla, A. , Muellerova, H.
Value in Health. 2013. 16(7):A723.
Initiation of pharmacological treatment in Parkinson’s disease in the UK: A clinical practice research datalink retrospective study
Bineau, S. , Guelfucci, F. , Neine, M.-E. , Aballéa, S. , Milea, D.
Journal of the Neurological Sciences. 2013. 333():e88.
Association of idiopathic polyneuropathy and incident Parkinson’s disease: A population-based observational study
Andersohn, F. , Miclea, A. , Ismail, C. , Arnold, N. , Guo, D. , Nisslein, T. , Conradt, C.
Journal of the Neurological Sciences. 2013. 333():e98.
Temporal trends in the prescribing of disease modifying anti-rheumatic drugs for rheumatoid arthritis and the impact of guidelines
Wallace, Gemma L. , Edwards, C.J. , Arden, Nigel K. , Prieto-Alhambra, Daniel , Judge, Andrew
Arthritis and Rheumatism. 2013. 65():S83.
The relative risk of aortic aneurysm in patients with giant cell arteritis compared with the general population
Robson, Joanna , Kiran, Amit , Maskell, Joseph , Hutchings, Andrew , Arden, Nigel K. , Dasgupta, Bhaskar
, Hamilton, William , Emin, Akan , Culliford, David , Luqmani, Raashid A.
Arthritis and Rheumatism. 2013. 65():S384.
An analysis of healthcare resource utilization among patients undergoing total knee arthroplasty in the
United Kingdom
Raluy, Mireia , Schoenfeld, Michael , Lambrelli, Dimitra , Wang, Meng , Wu, Ning , Chen, Shih-Yin ,
Burge, Russel
Arthritis and Rheumatism. 2013. 65():S423-S424.
Incidence of and risk factors for clinical fractures in patients with systemic lupus erythematosus and matched controls: A population-based study in the United Kingdom
Bultink, Irene , Harvey, Nicholas , Lalmohamed, Arief , Cooper, Cyrus , Lems, Willem , Van Staa, Tjeerd ,
De Vries, Frank
Arthritis and Rheumatism. 2013. 65():S515.
The diagnostic accuracy of rheumatoid factor testing in primary Care
Miller, Anne , Nightingale, Alison L. , Sammon, Cormac J. , Holt, Tim , Mahtani, Kamal R. , McHugh, Neil
, De Vries, Corinne S. , Luqmani, Raashid A.
Arthritis and Rheumatism. 2013. 65():S964-S965.
What is the risk of having a total hip or knee replacement for patients with lupus?
Mukherjee, Sandeep , Culliford, David , Arden, Nigel K. , Edwards, Christopher J.
Arthritis and Rheumatism. 2013. 65():S1070-S1071.
Anti-dementia drugs in patients with Alzheimer’s disease and the risk of developing seizures or epilepsy: A populationbased nested case-control analysis
Imfeld, P. , Bodmer, M. , Jick, S.S. , Meier, C.R.
International Journal of Clinical Pharmacy. 2013. 35(5):871.
Hormone replacement therapy and the risk of developing gout
Bruderer, S. , Jick, S.S. , Meier, C.R.
International Journal of Clinical Pharmacy. 2013. 35(5):886.
Diuretics and the risk of incident rosacea
Spoendlin, J. , Jick, S.S. , Meier, C.R.
International Journal of Clinical Pharmacy. 2013. 35(5):962-963.
Mortality and risk factors for death in patients with multiple sclerosis in a large population-based cohort
Vassilev, Z. , Li, L. , Falcone, G. , Wallander, M.-A. , Jick, S. , Bromley, S.
Multiple Sclerosis. 2013. 19(11):343-344.
Factors associated with time to triple therapy in newly diagnosed COPD patients in the UK general practice research database
Wurst, Keele E. , Bushnell, Greta , Shukla, Amit , Muellerova, Hana , Davis, Kourtney J.
Pharmacoepidemiology and Drug Safety. 2013. 22():33.
Anti-malarial chemoprophylaxis and the risk of developing neuropsychiatric disorders
Schneider, Cornelia , Adamcova, Miriam , Jick, Susan S. , Miller, Mary K. , Schlagenhauf, Patricia , Rhein,

90.
91.
92.
93.
94.
95.
96.
97.
98.
99.
100.
101.
102.
103.
104.
105.
Hans-Georg , Meier, Christoph R.
Pharmacoepidemiology and Drug Safety. 2013. 22():65.
Metformin use in prostate cancer and the risk of death and metastasis in patients with type 2 diabetes
Bensimon, Leah , Yin, Hui , Suissa, Samy , Pollak, Michael N. , Azoulay, Laurent
Pharmacoepidemiology and Drug Safety. 2013. 22():110.
Persistence to tamoxifen and aromatase inhibitors for the treatment of breast cancer-accounting for temporary treatment discontinuations
Huiart, Laetitia , Ferdynus, Cyril , Dell'Aniello, Sophie , Giorgi, Roch , Suissa, Samy
Pharmacoepidemiology and Drug Safety. 2013. 22():112.
Angiotensin II receptor blockers and the risk of dementia
Goh, Kah Lay , Douglas, Ian , Bhaskaran, Krishnan , Evans, Stephen , Smeeth, Liam
Pharmacoepidemiology and Drug Safety. 2013. 22():170-171.
The risk of incident rosacea associated with psychiatric diseases and psychotropic drug therapy
Spoendlin, Julia , Bichsel, Fabian , Voegel, Johannes J. , Jick, Susan S. , Meier, Christoph R.
Pharmacoepidemiology and Drug Safety. 2013. 22():198-199.
Aspirin use in prostate cancer and the risk of death and metastasis
Assayag, Jonathan , Azoulay, Laurent , Yin, Hui , Pollak, Michael N. , Suissa, Samy
Pharmacoepidemiology and Drug Safety. 2013. 22():211.
Risk of solid organ transplant rejection following vaccination with glaxosmithkline’s inactivated adjuvanted
(AS03) a/H1N1 pandemic influenza vaccine
Cohet, Catherine , Haguinet, Franc¸ois , Webb, Dave , Logie, John , Rosillon, Dominique , Shinde, Vivek ,
Dos Santos, Gaël
Pharmacoepidemiology and Drug Safety. 2013. 22():263.
A cohort analysis to measure the effect of orlistat or bariatric surgery on weight and body mass index in a general UK population sample
Douglas, Ian J. , Bhaskaran, Krishnan , Smeeth, Liam
Pharmacoepidemiology and Drug Safety. 2013. 22():279.
Incidence of giant cell arteritis in clinical practice research datalink and cumulative use of prednisolone in patients treated for GCA
Petri, Hans , Nevitt, Alan , Sarsour, Khaled , Collinson, Neil , Napalkov, Pavel
Pharmacoepidemiology and Drug Safety. 2013. 22():410.
Combination therapy with metformin plus sulfonylureas versus metformin plus DPP-4 inhibitors and risk of all-cause mortality
Currie, C.J. , Jenkins-Jones, S. , Mukherjee, J. , Morgan, C.L.
Diabetologia. 2013. 56():S88-S89.
Association between first-line monotherapy with sulfonylurea versus metformin and risk of all-cause mortality
Jenkins-Jones, S. , Currie, C.J. , Mukherjee, J. , Morgan, C.L.
Diabetologia. 2013. 56():S89.
Exogenous insulin and risk of all-cause mortality in type 2 diabetes: A dose-response association
Holden, S.E. , Schernthaner, G. , Jenkins-Jones, S. , Currie, C.J.
Diabetologia. 2013. 56():S96.
Delay in treatment intensification increases the risks of cardiovascular events in patients with type 2 diabetes
Paul, S. , Thorsted, B.L. , Wolden, M. , Klein, K. , Khunti, K.
Diabetologia. 2013. 56():S534-S535.
Prescribing trends of piroxicam in general practice: How has regulatory action impacted the prescribing demographics of piroxicam?
Wong, J. , Datta-Nemdharry, P.
Drug Safety. 2013. 36(9):934-935.
Breast cancer biology and risk of venous thromboembolism
Walker, A.J. , West, J. , Card, T.R. , Crooks, C. , Kirwan, C.C. , Grainge, M.J.
European Journal of Cancer. 2013. 49():S305-S306.
Which colorectal cancer patients get venous thromboembolism?
Walker, A.J. , West, J. , Card, T.R. , Crooks, C. , Humes, D.J. , Grainge, M.J.
European Journal of Cancer. 2013. 49():S308.
Potentially inappropriate prescribing among older people in the United Kingdom: A cross-sectional study using the Clinical Practice Research Datalink
Bradley, Marie , Fahey, Tom , Cahir, Caitriona , Hughes, Carmel , Williams, Tim , Padmanabhan, Shivani
International Journal of Pharmacy Practice. 2013. 21():12-13.

106.
107.
108.
109.
110.
111.
112.
113.
114.
115.
116.
117.
118.
119.
120.
121.
Adherence to anti-asthmatic inhaled corticosteroids: Measurements for the UK
Taylor, Amelia , D Smith, Murray , Chen, Li-Chia
International Journal of Pharmacy Practice. 2013. 21():97-98.
Evaluation of a pilot study involving MUR provision in Italy, using web-based data capture
Manfrin, Andrea , Krska, Janet , Caparrotta, Laura
International Journal of Pharmacy Practice. 2013. 21():113-114.
Impact of the ‘better care better value’ prescribing policy on the utilisation of renin-angiotensin system drugs in primary care in England
Baker, Amanj , Chen, Li-Chia , Godman, Brian , Elliott, Rachel
International Journal of Pharmacy Practice. 2013. 21():115-116.
Features of cancer in teenagers and young adults (TYA) presenting to primary care in the uk: A populationbased nested case-control study
Dommett, R. , Stevens, M. , Redaniel, T. , Hamilton, W. , Martin, R.
Pediatric Blood and Cancer. 2013. 60():3.
Comparative benefit of malaria chemoprophylaxis modelled in United Kingdom travellers
Toovey, S. , Nieforth, K. , Smith, P. , Patricia, S. , Adamcova, M. , Tatt, I. , Tomianovic, D. , Schnetzler, G.
Tropical Medicine and International Health. 2013. 18():214-215.
Drug utilization study of malaria chemoprophylaxis regimens
Bloechliger, M. , Schlagenhauf, P. , Toovey, S. , Adamcova, M. , Schnetzler, G. , Tatt, I. , Tomianovic, D. ,
Jick, S.S. , Meier, C.
Tropical Medicine and International Health. 2013. 18():219.
Are COPD and diabetes mellitus risk factors for herpes zoster?
Forbes, Harriet , Bhaskaran, Krishnan , Thomas, Sara , Smeeth, Liam , Langan, Sinead
European Journal of Epidemiology. 2013. 28(1):S13.
Acute maternal infection and risk of pre-eclampsia: A populationbased case-control study
Minassian, Caroline , Thomas, Sara L. , Williams, David J. , Campbell, Oona , Smeeth, Liam
European Journal of Epidemiology. 2013. 28(1):S70.
Associations between body mass index and a range of cancers: A population-based study within the UK
Clinical Practice Research Datalink
Bhaskaran, Krishnan , Douglas, Ian , Forbes, Harriet , Smeeth, Liam
European Journal of Epidemiology. 2013. 28(1):S97.
Exploring multiple imputation with time-dependent covariates in survival analysis: Body mass index and total knee replacement
Culliford, David
European Journal of Epidemiology. 2013. 28(1):S134-S135.
Development of a novel method for recruitment of cases of druginduced cholestatic liver injury to a genetic epidemiology cohort
Wing, Kevin , Douglas, Ian , Bhaskaran, Krishnan , Smeeth, Liam , Van Staa, Tjeerd-Pieter
European Journal of Epidemiology. 2013. 28(1):S139.
Incidence of venous thromboembolism in and around pregnancy using linked primary and secondary care data: A cohort study and meta-analysis
Sultan, Alyshah Abdul , Tata, Laila , Grainge, Matthew , West, Joe
European Journal of Epidemiology. 2013. 28(1):S151.
Cardiovascular safety in the ustekinumab clinical development programme: Final update with up to 5 years of follow-up
Reich, K. , Lebwohl, M. , Griffiths, C.E.M. , Szapary, P.
British Journal of Dermatology. 2013. 169():55.
Validation of ukpds risk engine predictions among patients with type 2 diabetes routinely managed in uk primary care
Bannister, Christian A. , Poole, Chris D. , Jenkins-Jones, Sara , Morgan, Christopher L.L. , Currie, Craig J. ,
Elwyn, Glyn
Diabetes. 2013. 62():A71.
Diabetic kidney disease (DKD) in UK patients with type 2 diabetes (T2D)
Ruzafa, Javier Cid , Paczkowski, Rosirene , Boye, Kristina S. , Di Tanna, Gian Luca , Sheetz, Matthew J. ,
Donaldson, Robert , Breyer, Matthew D. , Neasham, David , Voelker, James R.
Diabetes. 2013. 62():A397.
Prevalence of psoriasis in patients with type 2 diabetes
Brodovicz, Kimberly G. , Liu, Zhiwen , Engel, Samuel S. , Alexander, Charles M. , Girman, Cynthia J.
Diabetes. 2013. 62():A411.
122. Glucose lowering treatment with pioglitazone in combination with dipeptidyl peptidase-4 inhibitors (DPP4I)

123.
124.
125.
126.
127.
128.
129.
130.
131.
132.
133.
134.
135.
136.
137.
138. in routine clinical practice
Morgan, Christopher L.L. , Puelles, Jorge , Poole, Chris D. , Lee, Chris , Currie, Craig J.
Diabetes. 2013. 62():A665.
Diabetic kidney disease (DKD) in UK patients with type 1 diabetes (T1D)
Ruzafa, Javier Cid , Paczkowski, Rosirene , Boye, Kristina S. , Di Tanna, Gian Luca , Sheetz, Matthew J. ,
Donaldson, Robert , Breyer, Matthew D. , Neasham, David , Voelker, James R.
Diabetes. 2013. 62():A694.
Vitamin K antagonist treatment patterns and persistence after venous thromboembolism in noncancer patients: VTE Epidemiology Group (VEG) Study
Cohen, A. , Martinez, C. , Wallenhorst, C. , Bamber, L.
Journal of Thrombosis and Haemostasis. 2013. 11():26-27.
Risk factors for recurrent venous thromboembolism: VTE Epidemiology Group (VEG) Study
Martinez, C. , Katholing, A. , Cohen, A.
Journal of Thrombosis and Haemostasis. 2013. 11():226.
Rates and trends of pelvic inflammatory disease and ectopic pregnancy in england up to 2011: What can these data tell us about chlamydia epidemiology and control?
Woodhall, S.C. , Wetten, S. , Ross, J. , Williams, T. , Hughes, G. , Soldan, K.
Sexually Transmitted Infections. 2013. 89():.
Giant cell arteritis-incidence and mortality
Yates, M. , Mukhtyar, C. , Igali, L. , Watts, R. , MacGregor, A.
Annals of the Rheumatic Diseases. 2013. 72():.
Epidemiology of idiopathic inflammatory myopathies in england-a database analysis
Tran, T.N. , Steffey, A. , Caspard, H.
Annals of the Rheumatic Disease. 2013. 71():.
Case validation in research using large databases
García Rodríguez, L.
Annals of the Rheumatic Diseases. 2013. 72():.
Statin use is associated with improved survival in patients with oesophageal cancer: A survival analysis using the UK general practice research database and national cancer registry
Alexandre, L. , Clark, A. , Bhutta, H. , Lewis, M.P. , Holt, S. , Hart, A.R.
Gut. 2013. 62():A12-A13.
Aspirin use in prostate cancer and the risk of death and metastasis
Assayag, Jonathan , Azoulay, Laurent , Yin, Hui , Pollak, Michael N. , Suissa, Samy
Journal of Clinical Oncology. 2013. 31(15):.
Antibiotic prescribing in primary care for end-of-life cancer patients
Gao, Wei , Spicer, James F. , Higginson, Irene
Journal of Clinical Oncology. 2013. 31(15):.
Long-acting beta-agonists and asthma exacerbations requiring short courses of oral corticosteroids: A multicategory exposure marginal structural models analysis
Ali, A.K. , Hartzema, A.G. , Hendeles, L. , Lu, X. , Winterstein, A.G. , Segal, R.
Value in Health. 2013. 16(3):A231.
Prescribing long-acting beta-agonists as monotherapy to adults with controlled and uncontrolled asthma
Ali, A.K. , Hartzema, A.G.
Value in Health. 2013. 16(3):A241.
Ldl-c level and goal attainment among patients who switch from higher-efficacy lipid lowering therapies to simvastatin
Cao, X. , Tunceli, K. , Ambegaonkar, B. , Mavros, P.
Value in Health. 2013. 16(3):A275.
Cardiovascular safety in the ustekinumab clinical development program: Final update with up to 5 years of follow-up
Reich, Kristian , Griffiths, C.E.M. , Lebwohl, Mark , Szapary, Philippe
Journal of the American Academy of Dermatology. 2013. 68(4):AB194.
Gout is an independent risk factor for all types of vascular disease: A retrospective cohort study in the UK general practice research database
Clarson, Lorna E. , Hider, Samantha L. , Belcher, John , Heneghan, Carl , Roddy, Edward , Mallen,
Christian D.
Rheumatology (United Kingdom). 2013. 52():i38-i39.
The risk of a subsequent cancer diagnosis after PMR: A primary care database study
Muller, Sara , Mallen, Christian D. , Belcher, John , Helliwell, Toby , Hider, Samantha L.
Rheumatology (United Kingdom). 2013. 52():i40.

1.
3.
4.
139.
140.
141.
142.
143.
144.
145.
146.
147.
148.
2.
Predictors of aortic aneurysms for giant cell arteritis subjects
Robson, Joanna , Kiran, Amit , Maskell, Joe , Arden, Nigel , Hutchings, Andrew , Emin, Akan , Culliford,
David , Dasgupta, Bhaskar , Hamilton, William , Luqmani, Raashid
Rheumatology (United Kingdom). 2013. 52():i149-i150.
Giant cell arteritis: Over-diagnosed?
Yates, Max , Watts, Richard A. , Igali, Laszlo , Mukhtyar, Chetan , Macgregor, Alex
Rheumatology (United Kingdom). 2013. 52():i170-i171.
Adverse prognosis of asymptomatic at rial fibrillation detected incidentally: A case for screening
Freedman, S. Ben , Katholing, Anja , Martinez, Carlos
Journal of the American College of Cardiology. 2013. 61(10):E371.
The power of information for diabetes research and self-care patient views in Northwest London
Balasanthiran, A. , Papoutsi, C. , Shotliff, K. , Bell, D. , Majeed, A. , Marston, C. , Reed, J.
Diabetic Medicine. 2013. 30():126.
Use of depot medroxyprogesterone acetate contraception and incidence of bone fracture
Lanza, Lee L. , McQuay, Lisa J. , Rothman, Kenneth J. , Bone, Henry G. , Kaunitz, Andrew M. , Harel,
Zeev , Ataher, Quazi , Ross, Douglas , Arena, Philip L. , Wolter, Kevin D.
Obstetrics and Gynecology. 2013. 121(3):593-600.
Incidence of eating disorders in the UK: Findings from the UK General Practice Research Database
Micali, Nadia , Hagberg, Katrina W. , Treasure, Janet L.
The Lancet. 2013. 381():S75.
Mortality after a hip fracture in the United Kingdom: 2000 - 2011
Klop, Corinne , Welsing, Paco , Cooper, Cyrus , Bijlsma, Johannes , Leufkens, Hubert , De Vries, Frank
Journal of Bone and Mineral Research. 2013. 28():.
Incidence of and risk factors for clinical fractures in patients with systemic lupus erythematosus and matched controls: A population-based study in the united kingdom
Bultink, Irene , Harvey, Nicholas , Lalmohamed, Arief , Cooper, Cyrus , Lems, Willem , Van Staa, Tjeerd ,
De Vries, Frank
Journal of Bone and Mineral Research. 2013. 28():.
The incidence, resource utilization and financial costs of treating children with attention deficit/hyperactivity disorder (ADHD) in the United Kingdom (UK)
Holden, S.E. , Setyawan, J. , Coghill, D. , Hodgkins, P. , Currie, C.J.
European Psychiatry. 2013. 28():.
The prevalence of hereditary haemorrhagic telangiectasia in the UK and associations with sex, region of residence and socioeconomic status: A population-based study
Donaldson, J.W. , McKeever, T.M. , Hall, I.P. , Hubbard, R.B. , Fogarty, A.W.
Hematology Reports. 2013. 5():23.
Combining Data in Multi-Country Studies: Mega-Analysis vs. Meta-Analysis
Marloes T Bazelier, Joan Bentzen, Peter Vestergaard, Hubert GM Leufkens, Frank de Vries.
Pharmacoepidemiology and Drug Safety, 2012; 21: S11
Pattern of Anticoagulation Control and Risk of Stroke, Bleeding and Mortality
Hendrika A van den Ham, Olaf H Klungel, Hubert GM Leufkens, Tjeerd P van Staa.
Pharmacoepidemiology and Drug Safety, 2012; 21: S22
The Use of Single, Dual, or Triple Antithrombotic Therapy and the Risk of Bleeding Events in Patients with Atrial Fibrillation
Laurent Azoulay, Sophie Dell’Aniello, Teresa Simon, Christel Renoux, Samy Suissa.
Pharmacoepidemiology and Drug Safety, 2012; 21: S22
Heralding of STEMI and NSTEMI: A Prospective CALIBER Study
Emily Herrett, Julie George, Harry Hemingway, Liam Smeeth.
Pharmacoepidemiology and Drug Safety, 2012; 21: S24

5.
6.
Characteristics of Patients Initiating Oral Antidiabetic Therapy in the UK: Evidence of Delayed
Treatment?
Andrew Maguire, Beth Mitchell.
Pharmacoepidemiology and Drug Safety, 2012; 21: S27
Databases, Biologics, and Biomarkers: The Challenges and Rewards of Incorporating Biological
Specimens in Pharmacoepidemiologic Research
Leah B Sansbury, Kimberly A Wilson, Joanna F Haas, Bruce Carleton, Tjeerd-Pieter van Staa, Catherine
Schafer.
Pharmacoepidemiology and Drug Safety, 2012; 21: S38
7.
8.
Use of Antimalarial Chemoprophylaxis and the Risk of Developing Eye Disorders
Cornelia Schneider, Miriam Adamkova, Susan S Jick, Patricia Schlagenhauf, Katie Miller, Hans-Georg Rhein,
Christoph R Meier.
Pharmacoepidemiology and Drug Safety, 2012; 21: S93
Trends in Paediatric ADHD Drug Prescription in the UK and Cardiovascular Event Rates
Raphaelle Beau Lejdstrom, Stephen JW Evans, Ian Douglas, Liam Smeeth.
Pharmacoepidemiology and Drug Safety, 2012; 21: S136
9. Risk of Acute Renal Failure Likely Due to Concurrent Use of ACE-Inhibitors, Angiotensin Receptors
Blockers, Diuretics and Anti-Inflammatory Drugs
Francesco Lapi, Laurent Azoulay, Hui Yin, Samy Suissa
Pharmacoepidemiology and Drug Safety, 2012; 21: S163
10. Proton Pump Inhibitors and Traditional Nonsteroidal Anti-Inflammatory Drugs and the Risk of Acute
Interstitial Nephritis and Acute Kidney Injury
Charles E Leonard, Cristin P Freeman, Craig W Newcomb, Peter P Reese, Maximilian Herlim, Warren B
11.
Bilker, Sean Hennessy, Brian L Strom.
Pharmacoepidemiology and Drug Safety, 2012; 21: S179
Nonsteroidal Anti-Inflammatory Drug Use and Brain Tumour Risk: A Nested Case-Control Study in the
General Practice Research Database
Michael A O’Rorke, Finian J Bannon, Liam J Murray, Carmel M Hughes, Marie M Cantwell, Anna T Gavin,
Chris R Cardwell.
Pharmacoepidemiology and Drug Safety, 2012; 21: S180
12. Orlistat and the Risk of Acute liver Injury: A Self- Controlled Case-Series Study in United Kingdom
General Practice Research Database
Julia Langham, Liam Smeeth, Ruth Brauer, Krishnan Bhaskaran, Ian Douglas.
Pharmacoepidemiology and Drug Safety, 2012; 21: S190
13. Risk of Incident Cardiovascular Disease Events in Patients with Psoriasis: A Retrospective Cohort Study
14.
Using the General Practice Research Database
Paola Primatesta, Estel Plana, Zuleika Aponte Torres.
Pharmacoepidemiology and Drug Safety, 2012; 21: S192
Change in Exposure in Studies of Chronic Conditions: Insights from a Mixed Effects Multinomial Logit
Model
Maurille Feudjo Tepie, Andrew Roddam, Cathy Critchlow, Andrew Taylor, Samara Ferguson, Shelley Fordred,
Jonathan Bayly.
Pharmacoepidemiology and Drug Safety, 2012; 21: S252
15. Risk of Acute Myocardial Infarction (AMI), Stroke, or Death in GPRD Patients Treated with
Olmesartan (Olm) or Other Angiotensin Receptor Blockers (ARBs)
Esther H Zhou, Kate Gelperin, David J Graham, Mark Levenson, Martin Rose, Ya-Hui Hsueh, Tarek A
Hammad.
Pharmacoepidemiology and Drug Safety, 2012; 21: S254

16. Diuretics and the Risk of Developing Gout
Saskia G Bruderer, Susan S Jick, Christoph R Meier.
Pharmacoepidemiology and Drug Safety, 2012; 21: S256
17. Spironolactone and the Risk of Breast Cancer: A Cohort Study
Isla S Mackenzie, Thomas M MacDonald, Alastair M Thompson, Steven Morant, Li Wei.
Pharmacoepidemiology and Drug Safety, 2012; 21: S258
18. Cardiovascular Diseases and Drugs and the Risk of Developing Rosacea
Julia Spoendlin, Johannes J Voegel, Susan S Jick, Christoph R Meier.
Pharmacoepidemiology and Drug Safety, 2012; 21: S259
19. The Use of Pioglitazone and the Risk of Bladder Cancer in Patients with Type 2 Diabetes
Laurent Azoulay, Hui Yin, Kristian B Filion, Jonathan Assayag, Agnieszka Majdan, Michael Pollak, Samy
Suissa, Samy Suissa.
Pharmacoepidemiology and Drug Safety, 2012; 21: S271
20. Type 2 Diabetes Mellitus and Cancer Risk: A Population-Based Study
Jinghua He, Tzuyung D Kou, Kimberly G Brodovicz, Samuel S Engel, Amy Sun, Cynthia J Girman.
Pharmacoepidemiology and Drug Safety, 2012; 21: S273
21. Estimating Chronic Kidney Disease in a UK population with Type II Diabetes Mellitus
Claudia S Cabrera, Alex Asiimwe, Alison Lee.
Pharmacoepidemiology and Drug Safety, 2012; 21: S273
22. Algorithm To Estimate Duration of Known Type 2 Diabetes in Electronic Healthcare Databases
Kimberly G Brodovicz, T Doug Kou, Rishi Desai, Se Li, Samuel S Engel, Charles M Alexander, Cynthia J
Girman.
Pharmacoepidemiology and Drug Safety, 2012; 21: S274
23.
24.
Using Functional Principal Component Analysis (FPCA) for Sparse Longitudinal Data (SLD): Example of HbA1c in Patients with Diabetes Mellitus
Therese M Sheppard, William G Dixon.
Pharmacoepidemiology and Drug Safety, 2012; 21: S274
Diabetes Mellitus, Antidiabetic Drugs and the Risk of Developing Rosacea
Julia Spoendlin, Johannes J Voegel, Susan S Jick, Christoph R Meier.
Pharmacoepidemiology and Drug Safety, 2012; 21: S275
25. Metformin Does Not Alter the Risk of Lung Cancer: A Case–Control Analysis
Michael Bodmer, Claudia Becker, Christian Meier, Susan SJick, Christoph R Meier.
Pharmacoepidemiology and Drug Safety, 2012; 21: S278
26. Utilisation and Characteristics of New Users of Oral Antidiabetes Drugs (OAD) in the UK: 2006 2010
Andrew Maguire, Beth Mitchell.
Pharmacoepidemiology and Drug Safety, 2012; 21: S285
27. The Prescribing of Fibrates in General Practice in the UK and the Impact of Regulatory Advice
Katherine L Donegan.
Pharmacoepidemiology and Drug Safety, 2012; 21: S289
28. Use of Bayesian Method To Predict Missing Lifestyle Information in the General Practice Research
Database (GPRD)
Jamie T Laudati, Tzuyung D Kou, Kimberly G Brodovicz, Cynthia J Girman, Hanzhe Zheng.
Pharmacoepidemiology and Drug Safety, 2012; 21: S303
29. A Clinical Classification Dictionary for Read Codes in the General Practice Research Database
Hoa V Le, Chi T Truong, David Webb, Lakshmi Mynepalli, Elizabeth Hodgson, Dimitri Bennett, John Logie,
Carlyne Averell.

Pharmacoepidemiology and Drug Safety, 2012; 21: S304
30. Developing Quality Scores for Electronic Health Records for Clinical Research
A Rosemary Tate, Natalia Beloff, Timothy Williams, Shivani Puri, Tjeerd van Staa.
Pharmacoepidemiology and Drug Safety, 2012; 21: S305
31. Anti-Dementia Drugs in Patients with Alzheimer’s Disease and the Risk of Developing Seizures or
Epilepsy: A Population-Based Nested Case–Control Analysis
Patrick Imfeld, Michael Bodmer, Susan S Jick, Christoph R Meier.
Pharmacoepidemiology and Drug Safety, 2012; 21: S332
32. The Role of Surveillance Bias in the Incidence of the Myelodysplastic Syndromes and Chronic
Myeloproliferative Disorders
Amanda B Wilson, Marianne N Prout, Tuhina Neogi, Susan Jick.
Pharmacoepidemiology and Drug Safety, 2012; 21: S336
33. Validation of Congenital Cardiac Malformations in the General Practice Research Database
Fatmatta Kuyateh, Andrea V Margulis, Yulan Ding, Adel Abou-Ali, Marian Callaham, Tarek A Hammad.
Pharmacoepidemiology and Drug Safety, 2012; 21: S336
34. The Real Potential of Routine Electronic Health Records for Clinical Trials: Putting Them to the Test
Tjeerd P van Staa, Liam Smeeth, John Parkinson, Kourtney Davis, Hubert GM Leufkens.
Pharmacoepidemiology and Drug Safety, 2012; 21: S340
35. Use of Orlistat and Risk of Colorectal Cancer
Jin-Liern Hong, Robert Sandler, Christoph Meier, Susan Jick, Til Sturmer.
Pharmacoepidemiology and Drug Safety, 2012; 21: S345
36. Bisphosphonates and Esophageal Cancer in the GPRD
Alec Walker, Julie Chandler, Robert Lubwama, Nancy Santanello.
Pharmacoepidemiology and Drug Safety, 2012; 21: S345
37. Androgen Deprivation Therapy and the Risk of Colorectal Cancer in Prostate Cancer Patients
Jonathan Assayag, Hui Yin, Samy Suissa, Laurent Azoulay.
Pharmacoepidemiology and Drug Safety, 2012; 21: S346
38. Patterns of Antidepressant and Antipsychotic Use during Pregnancy
Andrea V Margulis, Elizabeth M Kang, Tarek A Hammad.
Pharmacoepidemiology and Drug Safety, 2012; 21: S371
39. Asthma Management in Pregnancy
Rachel Charlton, Annie Hutchison, Kourtney Davis, Corinne de Vries.
Pharmacoepidemiology and Drug Safety, 2012; 21: S381
40. Major Malformations in Babies Whose Mothers Had Pre-Existing Diabetes during Pregnancy
Anita McGrogan, Julia Snowball, Corinne S de Vries.
Pharmacoepidemiology and Drug Safety, 2012; 21: S388
41. Validation of Cataract Diagnosis in the UK General Practice Research Database
Elizabeth M Kang, Adel Abou-Ali, Simone P Pinheiro, Tarek A Hammad.
Pharmacoepidemiology and Drug Safety, 2012; 21: S394
42. Validation of Glaucoma Diagnosis in the UK General Practice Research Database
Adel Abou-Ali, Elizabeth M Kang, Simone P Pinheiro, Tarek A Hammad.
Pharmacoepidemiology and Drug Safety, 2012; 21: S394
43. An Algorithm Using Free-Text To Identify Sudden Cardiac Death in the General Practice Research
Database
Meghan Jones, Elizabeth Brunner, Elena Moscarelli, Chetan Shatapathy, Justo Sierra-Johnson, Tjeerd P van
Staa, Stephen Motsko.

Pharmacoepidemiology and Drug Safety, 2012; 21: S399
44. Prescribing of Strong Opioid Analgesics by UK Primary Care Physicians from 2000 to 2010
Che Suraya Zin, Li-Chia Chen, Roger D Knaggs.
Pharmacoepidemiology and Drug Safety, 2012; 21: S403
45. Exposure to Non Steroidal Anti-Inflammatory Drugs and Risk of Cervical Intraepithelial Neoplasia
Grade III
Janine A Glover, Jessica C Wilson, Liam J Murray, Lesley A Anderson, Christopher R Cardwell, Marie M
Cantwell, Carmel M Hughes.
Pharmacoepidemiology and Drug Safety, 2012; 21: S408
46. Etoricoxib in the UK: Continuing vs. New Users after the COX-2 Urgent Safety Restriction (USR)
Douglas J Watson, Vinay Mehta.
Pharmacoepidemiology and Drug Safety, 2012; 21: S415
47. Etoricoxib Prescribing by GPs in the UK after the COX- 2 Urgent Safety Restriction (USR)
Douglas J Watson, Vinay Mehta.
Pharmacoepidemiology and Drug Safety, 2012; 21: S415
48. Incidence of Cardiovascular (CV) Events with Etoricoxib in the UK after the COX-2 Urgent Safety
Restriction (USR)
Douglas J Watson, Vinay Mehta.
Pharmacoepidemiology and Drug Safety, 2012; 21: S415
49. Impact of Gastroesophageal Reflux Disease (GERD) Definition on Incidence Rate of Endoscopies among
Osteoporotic Patients
Robert N Lubwama, Julie Chandler, Tzuyung D Kou.
Pharmacoepidemiology and Drug Safety, 2012; 21: S421
50. Utilization Patterns of Strattera in Germany, Netherlands, Sweden and UK
Kwame Appenteng, Angelo Camporeale, Michel Denarie, Jennifer Millard, Stephen Motsko.
Pharmacoepidemiology and Drug Safety, 2012; 21: S427
51. Prescribing Trends of Dosulepin in General Practice: Reducing the Potential for Fatal Overdose
Jenny Wong, Suzie Seabroke
Pharmacoepidemiology and Drug Safety, 2012; 21: S433
52. A Comparison between the Standard Self Controlled Case Series Design and a Modification To Account for Events That Censor the Observation Period
Ruth Brauer, Liam Smeeth, Karim Anaya-Izquierdo, C Paddy Farrington, Heather Whitaker, Ian Douglas.
Pharmacoepidemiology and Drug Safety, 2012; 21: S439
53. A Cohort Analysis of the Association between Parkinson’s Disease and Cancer Using the UK General
Practice Research Database
Kevin Wing, Ian Douglas, Krishnan Bhaskaran, Liam Smeeth.
Pharmacoepidemiology and Drug Safety, 2012; 21: S442
54. Relative Risk of Myeloid Neoplasms in Patients Taking Benzodiazepines
Amanda B Wilson, Marianne N Prout, Tuhina Neogi, Susan Jick.
Pharmacoepidemiology and Drug Safety, 2012; 21: S447
55. Risk of Mortality (Including Sudden Cardiac Death) and Major Cardiovascular Events in Atypical and
Typical Antipsychotic Users: A Study with the General Practice Research Database
Tarita Murray-Thomas, Deven Patel, Meghan Jones, Elizabeth Brunner, Chetan Shatapathy, Stephen Motsko,
Tjeerd P van Staa.
Pharmacoepidemiology and Drug Safety, 2012; 21: S449
56. Risk of Cardiac Mortality (Including Sudden Cardiac Death) in Olanzapine Users: A Study with the
General Practice Research Database

Meghan Jones, Deven Patel, Elizabeth Brunner, Chetan Shatapathy, Stephen Motsko, Giedra Campbell, Tarita
Murray-Thomas, Tjeerd P van Staa.
Pharmacoepidemiology and Drug Safety, 2012; 21: S449
57. Risk of Developing Alzheimer’s Disease in Association with Influenza Infections
Patrick Imfeld, Stephen Toovey, Susan S Jick, Christoph R Meier.
Pharmacoepidemiology and Drug Safety, 2012; 21: S455
58. Relative Risk of Myeloid Neoplasms in Patients with Autoimmune Disease
Amanda B Wilson, Marianne N Prout, Tuhina Neogi, Susan Jick.
Pharmacoepidemiology and Drug Safety, 2012; 21: S467
59. The Risk of Developing Depression in Association with Previously Diagnosed Influenza Infection Delia
Bornand, Stephen Toovey, Susan S Jick, Christoph R Meier.
Pharmacoepidemiology and Drug Safety, 2012; 21: S476
60. 5-alpha Reductase Inhibitors and Prostate Cancer Incidence and Mortality among Men with Benign
Prostatic Hyperplasia
Krishnan Bhaskaran, Ian Douglas, Liam Smeeth.
Pharmacoepidemiology and Drug Safety, 2012; 21: S479
61. Hormone Replacement Therapy and the Risk of Developing Gout
Saskia G Bruderer, Susan S Jick, Christoph R Meier.
Pharmacoepidemiology and Drug Safety, 2012; 21: S479
The risk of childhood cancer with symptoms/signs presenting in primary care in the UK: A population-based
62. case-control study
Dommett, Rachel , Redaniel, Theresa , Martin, Richard , Hamilton, Willie , Stevens, Michael
Pediatric Blood and Cancer. 2012. 59(6):994.
Incidence of bleeding events in patients with atrial fibrillation
63.
64.
65.
Murray-Thomas, Tarita , Gallagher, Arlene , Clemens, Andreas , Ackermann, Diana , Bartels, Dorothee
Circulation. 2012. 126(21):.
Early effects on ischemic strokes after initiation of warfarin in patients with atrial fibrillation
Azoulay, Laurent , Dell'Aniello, Sophie , Simon, Teresa , Renoux, Christel , Suissa, Samy
Circulation. 2012. 126(21):.
Prevalence, associated comorbidities and treatment patterns among chronic kidney disease patients: An analysis using UK gprd data
Jick, S. , Hagberg, K.W. , O'Donoghue, D. , Jameson, K. , Ambegaonkar, B.M.
66.
67.
68.
69.
70.
71.
Value in Health. 2012. 15(7):A362.
Diabetes mellitus increases the risk of barrett's esophagus: Results from a large population based case control study
Iyer, Prasad , Heien, Herbert , Borah, Bijan , Cooper, Gregory , Das, Ananya , Chak, Amitabh
American Journal of Gastroenterology. 2012. 107():S15-S16.
Development of a “red flags” symptom list to assist with early recognition and diagnosis of amyotrophic lateral sclerosis
Williams, J.R. , Atassi, N. , Nakano, I. , Mora, J.S. , Drory, V. , Cudkowicz, M. , Shefner, J. , Chiò, A. ,
Mitsumoto, H. , Silani, V. , Zinman, L. , Weber, M. , Van Den Berg, L.H. , Robberecht W, . , Ronnevi, L.-O.
, Hardiman, O. , Bruijn, L. , Kerr, D.
Amyotrophic Lateral Sclerosis. 2012. 13():179.
Excess health care utilization prior to diagnosis of systemic lupus erythematosus in england
Steffey, Amy , Tran, Trung N. , Li, Jie , Caspard, Herve
Arthritis and Rheumatism. 2012. 64():S270-S271.
Incidence of systemic lupus erythematosus in England, 1998-2010
Caspard, Herve , Steffey, Amy , Li, Jie , Tran, Trung N.
Arthritis and Rheumatism. 2012. 64():S408.
Effectiveness of oral antidiabetic drugs in treatment naïve patients: Trends in HbA1c in the UK
Maguire, A. , Mitchell, B.
Diabetologia. 2012. 55():S26.
The association of HbA1c with risk of cardiovascular hospitalisations and all-cause mortality is u-shaped
Nichols, G.A. , Gotlib, S. , Parasuraman, S.
Diabetologia. 2012. 55():S81.

72.
73.
74.
75.
76.
77.
78.
79.
80.
81.
82.
83.
84.
85.
86.
HbA1c before and after starting treatment with metformin in a large diabetes type 2 cohort
Vazquez-Montes, M. , Stevens, R.J. , Oke, J. , Aronson, J.K. , Farmer, A.J.
Diabetologia. 2012. 55():S325.
Sudden unexpected death in children and teenagers with epilepsy: An epidemiological study
Besag, F.M. , Ackers, R. , Hughes, E. , Nashef, L. , Squier, W. , Murray, M. , Wong, I.
Epilepsia. 2012. 53():167.
Development of a “red flags” symptom list to assist with early recognition and diagnosis of amyotrophic lateral sclerosis
Williams, J. , Atassi, N. , Nakano, I. , Mora, J.S. , Drory, V. , Cudkowicz, M. , Shefner, J. , Chiò, A. ,
Mitsumoto, H. , Silani, V. , Zinman, L. , Weber, M. , Van Den Berg, L.H. , Robberecht, W. , Ronnevi, L.-O.
, Hardiman, O. , Bruijn, L. , Kerr, D.
European Journal of Neurology. 2012. 19():83.
How well are atrial fibrillation (AF) patients in the real world represented in the Contemporary Novel Oral
Anticoagulant (NOAC) AF trials?
Simon, T. , Huang, H.-Y. , Kawabata, H. , Azoulay, L. , Friberg, L. , Suissa, S.
European Heart Journal. 2012. 33():53.
Risk of stroke, myocardial infarction, bleeding and death in patients with incident atrial fibrillation: A cohort study of primary care in the UK
Martinez, C. , Rietbrock, S. , Evers, T.
European Heart Journal. 2012. 33():55.
Use of proton pump inhibitors and the risk of coronary events in patients receiving low-dose acetylsalicylic acid in UK primary care
Garcia Rodriguez, L.A. , Cea Soriano, L. , Bueno, H. , Lanas, A. , Johansson, S.
European Heart Journal. 2012. 33():304.
Prognostic models for people with stable coronary artery disease based on 115,500 patients from the
CALIBER study
Rapsomaniki, E. , Shah, A. , Denaxas, S. , Nicholas, O. , Hingorani, A. , Feder, G. , Timmis, A. ,
Hemingway, H.
European Heart Journal. 2012. 33():959.
Incidence, mortality and disease associations of pyoderma gangrenosum in the U.K.: A retrospective cohort study
Langan, S.M. , Gulliford, M. , Card, T. , Groves, R.W.
British Journal of Dermatology. 2012. 167():3.
Systematic review on the prevalence of malnutrition in general practice
McGurk, P. , Cawood, A. , Stratton, R. , Elia, M.
Gut. 2012. 61():A30.
Do statins prevent the histological subtypes of oesophageal cancer? Prospective data from the UK general practice research database (GPRD)
Bhutta, H.Y. , Alexandre, L. , Clark, A. , Holt, S. , Lewis, M. , Hart, A.
Gut. 2012. 61():A299-A300.
Blood pressure trajectories before death in patients with type 2 diabetes
Paul, Sanjoy , Klein, Kerenaftali , Thomas, Gijo , Khunti, Kamlesh
Diabetes. 2012. 61():A112-A113.
Hospitalization in patients with type 2 diabetes: A retrospective cohort study
Khalid, Javaria M. , Davis, Martha E. , Boye, Kristina S. , Curtis, Bradley , Raluy, Mireia , Maguire, Andrew
, Reaney, Matthew
Diabetes. 2012. 61():A243.
Increased risk of cancer in UK patients with type 2 diabetes
He, Jinghua , Kou, Tzuyung D. , Brodovicz, Kimberly G. , Sun, Amy , Engel, Samuel S. , Alexander,
Charles M. , Girman, Cynthia J.
Diabetes. 2012. 61():A363.
Five-year population level trajectory of HbA1c (AIC) and its association with mortality in patients with type
2 diabetes (T2DM)
Paul, Sanjoy K. , Best, Jennie H. , Khunti, Kamlesh , Klein, Kerenaftali
Diabetes. 2012. 61():A363.
Efficacy of insulin pump treatment in young adult patients with type 1 diabetes mellitus
Matejko, Bartłomiej , Cyganek, Katarzyna , Grzanka, Malgorzata , Kozek, Elzbieta , Malecki, Maciej T. ,
Klupa, Tomasz
Diabetes. 2012. 61():A593.
87. Dosage and duration of glimepiride therapy among patients with type 2 diabetes

88.
89.
90.
91.
92.
93.
94.
95.
96.
97.
98.
99.
100.
101.
Stender, Monika , Ambery, Philip , Koro, Carol
Diabetes. 2012. 61():A593.
Appropriate prescribing of combined hormonal contraceptives: Impact of medical eligibility criteria implementation on prescribing in the UK
Elizabeth Briggs, P. , Praet, C. , Humphreys, S. , Zhao, C.
European Journal of Contraception and Reproductive Health Care. 2012. 17():S38-S39.
Healthcare costs before and after diagnosis of depression in patients with unexplained pain: A retrospective cohort study using the United Kingdom general practice research database
Hong, J. , Reed, C. , Novick, D. , Lenox-Smith, A. , Happich, M.
International Journal of Neuropsychopharmacology. 2012. 15():232.
Development of a ''red flags'' symptom list to assist with early recognition and diagnosis of amyotrophic lateral sclerosis
Atassi, N. , Nakano, I. , Mora, J.S. , Drory, V. , Cudkowicz, M. , Shefner, J. , Chiò, A. , Mitsumoto, H. ,
Silani, V. , Zinman, L. , Weber, M. , Van Den Berg, L.H. , Robberecht, W. , Ronnevi, L-O. , Hardiman, O. ,
Bruijn, L. , Kerr, D. , Williams, J.R.
Journal of Neurology. 2012. 259(1):S52.
Impact of disease severity on the total, health-related, financial costs of treatment of people with rheumatoid arthritis in the United Kingdom
Poole, C.D. , Currie, C.J. , Holden, S. , Singh, A.
Value in Health. 2012. 15(4):A36-A37.
Features of childhood cancer in primary care: A population-based nested casecontrol study
Dommett, R.M. , Redaniel, T.R. , Stevens, M.C.G. , Hamilton, W. , Martin, R.M.
Archives of Disease in Childhood. 2012. 97():A5.
Update on cardiovascular safety of Ustekinumab in pooled phase 2 and 3 psoriasis clinical trials with up to 4 years of follow-up
Reich, K. , Langley, R.G. , Lebwohl, M. , Szapary, P.O. , Yeilding, N. , Hsu, M.C. , Griffiths, C.E.M.
Australasian Journal of Dermatology. 2012. 53():51-52.
Decreasing low-density lipoprotein cholesterol in relation to risk of cardiovascular and cerebrovascular events among people with type 2 diabetes
Li, L. , Ambegaonkar, B.M. , Reckless, J.P.D. , Jick, S.S.
European Journal of Preventive Cardiology. 2012. 19(1):S35.
Adult and pediatric ibd incidence in the UK: A large population-based study using the general practice research database
Siffledeen, Jesse S. , Fleming, Kate M. , Crooks, Colin , Card, Timothy R.
Gastroenterology. 2012. 142(5):S797.
Regional differences in the treatment of rheumatoid arthritis in the united kingdom
Edwards, Christopher J. , Arden, Nigel , Campbell, Jennifer , Van Staa, Tjeerd , Housden, Claire , Sargeant,
Ify
Rheumatology (United Kingdom). 2012. 51():iii129.
Temporal trends in the treatment of rheumatoid arthritis (RA) in the UK with reference to best practice
Edwards, Christopher J. , Arden, Nigel , Campbell, Jennifer , Van Staa, Tjeerd , Housden, Claire , Sargeant,
Ify
Rheumatology (United Kingdom). 2012. 51():iii129-iii130.
Risk of breast cancer recurrence is not increased by the use of local estrogen therapy among endocrinetreated patients
Le Ray, I. , Dell'aniello, S. , Bonnetain, F. , Suissa, S. , Azoulay, L.
Fundamental and Clinical Pharmacology. 2012. 26():40.
High dose atorvastatin associated with increased risk of significant hepatotoxicity in comparison to simvastatin: A retrospective cohort study using the UK general practice research database
Clarke, A.T. , Johnson, P.C.D. , Hall, G.C. , Ford, I. , Mills, P.R.
Journal of Hepatology. 2012. 56():S528.
Update on the cardiovascular safety of ustekinumab in pooled phase II and III psoriasis clinical trials with up to 4 years of follow-up
Reich, K. , Griffiths, C.E.M. , Lebwohl, M. , Szapary, P.O.
Journal of the American Academy of Dermatology. 2012. 66(4):AB206.
Hormone replacement therapy prevents failure after total knee (TKA) and hip (THA) arthroplasty: A population-based retrospective cohort study
Prieto-Alhambra, D. , Javaid, M. , Judge, A. , Maskell, J. , Cooper, C. , Arden, N.K.
Osteoarthritis and Cartilage. 2012. 20():S176-S177.
102. Estimating prosthesis survival following total hip replacement in the United Kingdom

103.
104.
105.
106.
107.
108.
109.
110.
111.
Culliford, D. , Judge, A. , Maskell, J. , Arden, N.
Osteoarthritis and Cartilage. 2012. 20():S180-S181.
Rate of venous thromboembolismby cancer type compared to the general population using multiple linked databases
Walker, A.J. , West, J. , Card, T.R. , Crooks, C. , Grainge, M.J.
Thrombosis Research. 2012. 129():S155-S156.
Sexuality
Rees, M.
Maturitas. 2012. 71():S8.
Strontium ranelate and risk of venous thromboembolism (VTE): An update of a retrospective cohort study in the UK general practice research database (GPRD)
Cooper, Cyrus , Deltour, Nicolas , Speirs, Chris , Meyer, Olivier , Reginster, Jean-Yves
Osteoporosis International. 2012. 23():S364-S365.
Increased risk of miscarriage and ectopic pregnancy in patients with irritable bowel syndrome
Khashan, Ali S. , Quigley, Eamonn M.M. , McNamee, Roseanne , McCarthy, Fergus P. , Shanahan, Fergus ,
Kenny, Louise C.
Reproductive Sciences. 2012. 19(3):240A.
Update on the cardiovascular safety of ustekinumab in pooled phase II & III psoriasis clinical trials with upto 4 years of follow-up
Reich, K. , Langley, R.G. , Lebwohl, M. , Szapary, P.O. , Yeilding, N. , Hsu, M.C. , Griffiths, C.E.M.
Seminars in Cutaneous Medicine and Surgery. 2012. 31(1):A12.
Antihypertensive drugs and the risk of developing gout
Bruderer, S. , Jick, S.S. , Meier, C.R.
International Journal of Clinical Pharmacy. 2012. 34(1):175-176.
Risk of developing Alzheimer's disease in association with influenza infections
Imfeld, P. , Toovey, S. , Jick, S.S. , Meier, C.R.
International Journal of Clinical Pharmacy. 2012. 34(1):228.
Risk of developing Rosacea in patients with asthma
Spoendlin, J. , Jick, S.S. , Meier, C.R.
International Journal of Clinical Pharmacy. 2012. 34(1):233.
Real-world effectiveness of asthma step-up options: Matched comparison of extrafine hydrofluoroalkanebeclometasone and inhaled corticosteroid/long-acting beta-agonist
Price, D.B. , Martin, R. , Barnes, N. , Roche, N. , Lee, A.J. , Dorinsky, P. , Burden, A. , Von Ziegenweidt, J.
, Chisholm, A. , Hillyer, E.V. , Colice, G.
Journal of Allergy and Clinical Immunology. 2012. 129(2):AB61.

1.
2.
3.
Statin Prescribing Following an Acute Coronary Syndrome: Are the NICE Guidelines Being Followed?
Boggon R, Eaton S, Timmis A, Hemingway H, Gabriel Z, Minhas I, van Staa T.
Pharmacoepidemiology and Drug Safety, 2011; 20: S20
Use of Thiazolidinediones and Risk of Osteoporotic Fracture: Disease or Drugs?
Bazelier M, Gallagher A, van Staa T, Cooper C, Leufkens H, Vestergaard P and De Vries F.
Pharmacoepidemiology and Drug Safety, 2011; 20: S26
Creating a Mother Baby Link and Pregnancy Register for a UK Population
Boggon R, Gallagher A, Williams T, van Staa T.
4.
5.
Pharmacoepidemiology and Drug Safety, 2011; 20: S44
Use of Thiazolidinediones and Risk of Osteoporotic Fracture: The Danish National Databases
Bazelier M, Gallagher A, van Staa T, Cooper C, Leufkens H, Vestergaard P.
Frank De Vries.
Pharmacoepidemiology and Drug Safety, 2011; 20: S119
Risk of Fracture in Patients with Myasthenia Gravis
Bazelier M, Pouwels S, Javaid K, Cooper C, Hilton-Jones D, Verschuuren J, van Staa T, De Vries F.
6.
7.
8.
Pharmacoepidemiology and Drug Safety, 2011; 20: S119
Cancer Recording and Mortality in the General Practice Research Database and Linked Cancer Registry,
Hospital and Death Certificate Data
Boggon R, Moller H, Gallagher A, Leufkens H, Hammad T, Zhang H, van Staa T
Pharmacoepidemiology and Drug Safety, 2011; 20: S162
STAtin-Induced Muscle Toxicity: Exploration Using the UK GEneral Practice Research Database -
Recruitment
Campbell J, van Staa TP, McCann G, O’Meara H, Pirmohamed M.
Pharmacoepidemiology and Drug Safety, 2011; 20: S183
Linkage of the General Practice Research Database (GPRD) with Other Data Sources
Gallagher AM, Puri S, van Staa TP.
Pharmacoepidemiology and Drug Safety, 2011; 20: S230
9. The Risk of Cancer Associated with Angiotensin-II Receptor Blockers
Bhaskaran K, Douglas I, Evans S, van Staa T, Smeeth L.
Pharmacoepidemiology and Drug Safety, 2011; 20: S279
10. Assessment of Long-Term Adverse Drug Reactions, Regulatory Needs and Methodological Challenges
Duijnhoven RG, Straus SMJM, van Staa TP, Moride Y, Grimaldi LM, De Bruin ML
Pharmacoepidemiology and Drug Safety, 2011; 20: S268
11. Impact of treatment persistence and compliance on health care resource utilisation and total health care cost in post menopausal women prescribed oral bisphosphonates – a retrospective study using the general practice research database (GPRD)
Murray-Thomas T, Patel D, Williams T, van Staa T
Value in Health, Volume 14 Number May 2011: A126
12. Clopidodgrel and statin prescribing patterns in acs patients – an observational study using linked secondary and primary care data in a uk population 2003-2009
Boggon R, Fox KA, Begg A, Ray K, Timmis A, Hemingway H, Emmas CE, Van staa T
Value in Health, Volume 14 Number Nov 2011: A368

13. Resource use in patients with acute coronary syndrome – an observational study across secondary and primary care in a UK population
Boggon R, Fox KA, Begg A, Ray K, Timmis A, Hemingway H, Emmas CE,Van staa T
Value in Health, Volume 14 Number Nov 2011: A382
14. Association between Minocycline and Thyroid Cancer in the GPRD: Preliminary Findings
Sigal Kaplan, Marian Callaham, Yulan Ding, Stephine Kee- ton, Mark Levenson, Naomi Lowy, Tarek Hammad.
Pharmacoepidemiology and Drug Safety, 2011; 20: S36
15. SSRIs Use during Pregnancy and the Risk of Cardiac Congenital Malformations using the General
Practice Research Database
Adel Abou-Ali, Marian Callaham, Fatmatta Kuyateh, Tarek A Hammad.
Pharmacoepidemiology and Drug Safety, 2011; 20: S43
16. Advancing the Field of Drug Safety in Pregnancy: A Decade of Abstracts Presented at ICPE
Deborah Covington, Kyna Gooden, Laura McKain.
Pharmacoepidemiology and Drug Safety, 2011; 20: S46
17. Swine Flu Vaccination in Pregnancy and Associated Miscarriage Risk
Cormac J Sammon, Anita McGrogan, Julia Snowball, Cor- inne S de Vries.
Pharmacoepidemiology and Drug Safety, 2011; 20: S58
18. Epidemiology of Pneumoconioses in the U.K. General Population
Rajeev K Amar, Susan S Jick, Daniel Rosenberg, Toby M Maher, Christoph R Meier
Pharmacoepidemiology and Drug Safety, 2011; 20: S61
19. Medications in Pregnancy Special Interest Group: Improving the Quality of Science and Expanding
Knowledge
Deborah Covington, Kyna Gooden, Laura McKain.
Pharmacoepidemiology and Drug Safety, 2011; 20: S73
20. Drug-/Radiation-Induced Interstitial Lung Disease in the UK General Population: Incidence, Drug Use and Characteristics at Diagnosis
Rajeev K Amar, Susan S Jick, Daniel Rosenberg, Toby M Maher, Christoph R Meier.
Pharmacoepidemiology and Drug Safety, 2011; 20: S84
21. An Analysis of HRT Usage between 2000 and 2009 Using GPRD in the UK
Jakob Petersen, Jane Woolley, Dervla Mahoney.
Pharmacoepidemiology and Drug Safety, 2011; 20: S101
22. A Cohort Study Using GPRD and MINAP Data To Investigate the Possible Drug Interaction between
Clopi- dogrel and Cytochrome P450 2C19 Inhibitors
Ian Douglas, Liam Smeeth, Aroon Hingorani, Anthony Grosso, Stephen Evans.
Pharmacoepidemiology and Drug Safety, 2011; 20: S123
23. Thiazolidinidiones and the Risk of Myocardial Infarction
Rohini K Hernandez, Timothy L Lash, Cathy W Critchlow, Susan S Jick.
Pharmacoepidemiology and Drug Safety, 2011; 20: S123
24. Antipsychotic Drugs and Risk of Idiopathic Venous Thromboembolism: A Nested Case Control Study
Using the GPRD
Chieko Ishiguro, Lin Li, Susan S Jick.
Pharmacoepidemiology and Drug Safety, 2011; 20: S130
25. Androgen Deprivation Therapy and the Risk of Stroke and Transient Ischemic Attacks in Patients with
Prostate Cancer
Laurent Azoulay, Hui Yin, Serge Benayoun, Jean-Francois Boivin, Samy Suissa.

Pharmacoepidemiology and Drug Safety, 2011; 20: S130
26. Effect of Simultaneous Use of Oestrogens and Statins on the Risk for Venous Thromboembolism in Post-
Menopausal Women
Ruben Duijnhoven, Sophie dell’Aniello, Christel Renoux, Vicky Tagalakis, Mirjam Knol, Olaf Klungel, Samy
Suissa.
Pharmacoepidemiology and Drug Safety, 2011; 20: S131
27. Differences in Oral Candidiasis Risk between Different Inhaled Corticosteroids
Alison L Nightingale, Annie Hutchison, Corinne S de Vries.
Pharmacoepidemiology and Drug Safety, 2011; 20: S141
28. Comparison of Retention Rates of First Line Anti-epileptic Drugs in Children in the UK
Raphaelle Beau, Ian Douglas, Evans Stephen, Tim Clayton, Liam Smeeth
Pharmacoepidemiology and Drug Safety, 2011; 20: S152
29. Comparison of Methods To Define Lifestyle Risk Factors in the General Practice Research Database
(GPRD)
Jamie T Laudati, Tzuyung D Kou, Kimberly A Wilson, Kimberly G Brodovicz, Cindy J Girman.
Pharmacoepidemiology and Drug Safety, 2011; 20: S169
30. Cancer Identification in the General Practice Research Data Base
A M Walker, J M Chandler, R Lubwama, N C Santanello.
Pharmacoepidemiology and Drug Safety, 2011; 20: S175
31. Impact of the Quality Outcomes Framework on Hypertension Coding in GPRD
Lesley H Wise,1 David Irvine,1 Motonobu Sakaguchi,2 Gregory Fusco.
Pharmacoepidemiology and Drug Safety, 2011; 20: S176
32. Association between Antidepressant Drugs and Cancer in the UK-Based General Practice Research
Database: A Cohort Study
Adel Abou-Ali, Elizabeth M Kang, Simone Pinheiro, Tarek A Hammad.
Pharmacoepidemiology and Drug Safety, 2011; 20: S192
33. Using the Self Controlled Case Series Method To Assess the Risk of Myocardial Infarction in GPRD-
Registered Users of Antipsychotic Agents
Ruth Brauer, Ian Douglas, Liam Smeeth.
Pharmacoepidemiology and Drug Safety, 2011; 20: S193
34. Migraine in Patients with Rosacea
Julia Spoendlin, Cornelia Schneider, Susan S Jick, Christoph R Meier.
Pharmacoepidemiology and Drug Safety, 2011; 20: S199
35. Agreement between COPD-Related Hospitaliza- tions Identified Using Two Sources: General Practice
Research Database (GPRD) and Linked Hospitalization Episode Statistics (HES) Data
Rachael L DiSantostefano, Richard Baxter, Hana Mu llerova.
Pharmacoepidemiology and Drug Safety, 2011; 20: S230
36. Impact of Look-Back Period on Baseline Patient Characteristics and Subsequent Risk Estimates in the
General Practice Research Database (GPRD)
Tzuyung D Kou, Kimberly G Brodovicz, Cindy J Girman
Pharmacoepidemiology and Drug Safety, 2011; 20: S254
37. Safety of Adjuvanted Pandemic Influenza Vac- cines: Background Rate of Narcolepsy in Europe
J Dieleman, C Lecomte, M Schuemie, Avan Rolleghem, A Hviid, H Svanstrom, D Mølgaard-Nielsen, J Jokinen,
H Nohynek, T Kilpi, J Storsaeter, N van der Maas, H Heijbel, L Arnheim-Dahlstrøm, P Sparen, C Sammon, C de
Vries, G Plazzi, A Menna, F Trotta, C Santuccio, K Johansen, P Kramarz, D Weibel, J Bonhoeffer, M
Sturkenboom.
Pharmacoepidemiology and Drug Safety, 2011; 20: S260

38. Assessing Treatment Patterns: Novel Methods and Applications
Sonia S Maruti, E Dawn Flick, Marloes Bazelier, Frank De Vries, Krista F Huybrechts, Drew Levy, Andrew
Roddam, Wei Dong.
Pharmacoepidemiology and Drug Safety, 2011; 20: S267
39. Use of Metformin or Other Antidiabetic Drugs and Pancreatic Cancer: A Case-Control Analysis
Michael Bodmer, Claudia Becker, Susan S Jick, Christoph R Meier.
Pharmacoepidemiology and Drug Safety, 2011; 20: S270
40. Macrogol Laxatives and Colorectal Cancer Risk
Rachel A Charlton, Julia M Snowball, Katherine Bloomfield, Corinne S de Vries.
Pharmacoepidemiology and Drug Safety, 2011; 20: S270
41. The Risk of Myocardial Infarction and Opioids Use for Non-Cancer Pain: A Nested Case-Control Study in
UK General Practice Research Database (GPRD)
Lin Li, Soko Setoguchi, Susan S Jick.
Pharmacoepidemiology and Drug Safety, 2011; 20: S271
42. Synergistic Effect of Type 2 Diabetes (T2D) and History of Pancreatitis on Pancreatic Cancer Risk: A
Retrospective Cohort Study from the General Practice Research Database (GPRD)
Kimberly G Brodovicz, Tzuyung D Kou, Charles M Alexander, Samuel Engel, Cynthia J Girman.
Pharmacoepidemiology and Drug Safety, 2011; 20: S283
43. Risk Factors Associated with the Incidence of Vaginitis and Balinitis among Patients with Type 2 Diabetes in a Community Practice Setting in the UK
Andres Gomez-Caminero, Ishan Hirji, Susan Andersson, Niklas Hammar.
Pharmacoepidemiology and Drug Safety, 2011; 20: S287
44. Risk Factors Associated with the Incidence of Urinary Tract Infections among Patients with Type 2
Diabetes in a Community Practice Setting in the UK
Andres Gomez-Caminero, Ishan Hirji, Susan Andersson, Niklas Hammar.
Pharmacoepidemiology and Drug Safety, 2011; 20: S287
45. Thiazolidinidiones and the Risk of Microvascular Disease
Rohini K Hernandez, Timothy L Lash, Cathy W Critchlow, Susan S Jick.
Pharmacoepidemiology and Drug Safety, 2011; 20: S289
46. Metformin or Other Antidiabetic Drugs and the Risk of Developing Alzheimer’s Disease: A Population-
Based Case-Control Study
Patrick Imfeld, Yolanda B Brauchli, Cornelia Schneider, Michael Bodmer, Susan S Jick, Christoph R Meier.
Pharmacoepidemiology and Drug Safety, 2011; 20: S289
47. Diabetes and the Risk of COPD
Cornelia Schneider, Susan S Jick, Ulrich Bothner, Christoph R Meier.
Pharmacoepidemiology and Drug Safety, 2011; 20: S292
48. Association between Antidepressant Drugs and Cataracts in the UK-Based General Practice Research
Database: A Cohort Study
Adel Abou-Ali, Elizabeth M Kang, Simone Pinheiro, Tarek A Hammad.
Pharmacoepidemiology and Drug Safety, 2011; 20: S294
49. Alzheimer’s Disease and the Risk of Subsequent Stroke or Transient Ischaemic Attack: A Population-
Based Nested Case-Control Analysis
Patrick Imfeld, Yolanda B Brauchli, Markus Schuerch, Noah J Robinson, Susan S Jick, Christoph R Meier.
Pharmacoepidemiology and Drug Safety, 2011; 20: S298
50. Patient’s Right to Self-Determination and Its Impact on All Cause Morality Risk Estimates in Dementia
Patients - A Observational Study Using General Practice Research Database (GPRD)
Tzuyung D Kou, Edward A Bortnichak.

Pharmacoepidemiology and Drug Safety, 2011; 20: S299
51. A Self-Controlled Case-Series Study To Assess the Effect of Orlistat on the Risk of Idiopathic Acute Liver
Injury, Using Data from the United Kingdom General Practice Research Database
Julia Langham, Ian Douglas, Ruth Brauer, Krishnan Bhas- karan, Liam Smeeth
Pharmacoepidemiology and Drug Safety, 2011; 20: S306
52. Different Approaches to Instrumental Variable Analysis of Antidiabetic Effect of Bezafibrate
Bing Cai, Sean Hennessy, Dylan Small, James H Flory, Thomas R Ten Have.
Pharmacoepidemiology and Drug Safety, 2011; 20: S310
53. How Long Do Children Stay on Antiepileptic Treatments in the UK?
Raphaelle Beau, Ian Douglas, Stephen Evans, Tim Clayton, Liam Smeeth.
Pharmacoepidemiology and Drug Safety, 2011; 20: S317
54. Impact of the Quality Outcomes Framework on Chronic Kidney Disease Coding in GPRD
Lesley H Wise, David Irvine, Motonobu Sakaguchi, Gregory Fusco
Pharmacoepidemiology and Drug Safety, 2011; 20: S323
55. Developing quality scores for electronic health records for clinical research: A study using the general practice research database.
Tate AR, Williams T, Puri S, Beloff N, Van Staa T.
International Conference on Information and Knowledge Management, 2011, Proceedings: 35-41.
56. Automatically estimating the incidence of symptoms recorded in GP free text notes.
Koeling R, Tate AR, Carroll JA.
International Conference on Information and Knowledge Management, 2011, Proceedings: 43-49.
Randomised Evaluations of Accepted Choices in Treatment (REACT) trials: Large-scale pragmatic trials within databases of routinely collected electronic healthcare records
57. Van Staa, Tjeerd-Pieter , Goldacre, Ben , Gulliford, Martin , Cassell, Jackie , Pirmohamed, Munir , Taweel,
Adel , Delaney, Brendan , Smeeth, Liam
Trials. 2011. 12():.
Survival after the first myocardial infarction is shorter in patients with COPD compared to the general
58.
59.
60.
61.
62.
63.
64.
65. population
Quint, J.K. , Herrett, E. , Timmis, A. , Hemingway, H. , Smeeth, L.
Thorax. 2011. 66():A45-A46.
Incidence of vascular outcomes in patients with atrial fibrillation
Gallagher, Arlene M. , Murray-Thomas, Tarita , Clemens, Andreas , Diana, Ackermann , Bartels, Dorothee
B.
Blood. 2011. 118(21):.
Adjunctive pharmacotherapy among initiators of ssri treatment for major depressive disorder: A cohort study using a UK primary care database
Ball, S. , Classi, P. , Dave, S. , Maguire, A. , Kim Le, T.
Value in Health. 2011. 14(7):A286.
Modelling the cost-effectiveness of orlistat as a treatment for obesity in primary care
Ara, R. , Blake, L.
Value in Health. 2011. 14(7):A416-A417.
Application of the subgroup identification tool using a health care database: Treatment response heterogeneity in type II diabetes
Chen, L. , Buesching, D. , Curtis, B. , Zagar, A. , Rotelli, M. , Delisle, F. , Lipkovich, I. , Peng, X.
Value in Health. 2011. 14(7):A486.
Alendronate tolerability before and after market introduction of generics
Petersen, J. , Jan, T. , Donegan, K. , Seabroke, S.
Drug Safety. 2011. 34(10):951.
Prescription trends for antipsychotics in patients with dementia in the UK
Donegan, K. , Davies, C. , Seabroke, S. , Wong, J.
Drug Safety. 2011. 34(10):999-1000.
Cause of death in patients with multiple sclerosis and controls: the General Practice Research Database
Bazelier, M.T. , Lalmohamed, A. , Van Staa, T. , Uitdehaag, B. , Leufkens, H. , De Vries, F.
Multiple Sclerosis. 2011. 17(10):S86.

66.
67.
68.
69.
70.
71.
72.
73.
74.
75.
76.
77.
78.
79.
80.
81.
82.
Risk of cataract in patients with multiple sclerosis: A population-based cohort study
Bazelier, M.T. , Mueller-Schotte, S. , Van Staa, T. , Uitdehaag, B. , Leufkens, H. , De Vries, F.
Multiple Sclerosis. 2011. 17(10):S306.
STARDUST-study of the treatment and prevalence of renal disease in UK diabetes mellitus type 2 patients
Lee, S. , Bilous, R.
Diabetologia. 2011. 54():S128.
Limitations in the study of type 2 diabetes and pancreatic cancer in electronic insurance claims and health record databases
Girman, C.J. , Kou, T.D. , Alexander, C.M. , O'Neill, E.A. , Engel, S. , Goldstein, B.J. , Brodovicz, K.G.
Diabetologia. 2011. 54():S312.
Cost of treating chronic lower back pain (CLBP) in patients consulting primary care physicians in the UK
Hong, J. , Reed, C. , Happich, M. , Novick, D.
European Journal of Pain Supplements. 2011. 5(1):125.
Cost of treating osteoarthritis in patients consulting primary care physicians in the UK
Hong, J. , Reed, C. , Happich, M. , Novick, D.
European Journal of Pain Supplements. 2011. 5(1):127.
Estimating the lifetime risk of total hip and knee replacement in the United Kingdom
Culliford, D. , Kiran, A. , Judge, A. , Arden, N.K.
Osteoarthritis and Cartilage. 2011. 19():S21.
Sudden unexpected death in epilepsy (SUDEP): Pediatric cases
Besag, F. , Ackers, R. , Nashef, L. , Hughes, E. , Wong, I.C.
Epilepsia. 2011. 52():260.
Effectiveness in primary care of low-dose acetylsalicylic acid, clopidogrel and dual antiplatelet therapy for the secondary prevention of coronary outcomes
Garcia Rodriguez, L.A. , Cea-Soriano, L. , Johansson, S. , Bueno, H.
European Heart Journal. 2011. 32():229.
Concomitant use of clopidogrel and proton pump inhibitors is not associated with an increased risk of coronary events
Garcia Rodriguez, L.A. , Cea-Soriano, L. , Johansson, S.
European Heart Journal. 2011. 32():415.
(W) Ezetimibe survival benefit in survivors of an acute myocardial infarction: A population-based study
Pauriah, M. , Elder, D.H. , Ogston, S. , Noman, A.Y.S. , Majeed, A. , Wyatt, J.C. , Struthers, A.D. , Choy,
A.M. , Lang, C.C.
European Heart Journal. 2011. 32():484.
Warfarin and the risk of major bleeding events in patients with atrial fibrillation: A population-based study
Azoulay, L. , Dell'aniello, S. , Simon, T. , Renoux, C. , Suissa, S.
European Heart Journal. 2011. 32():671-672.
Assessing treatment patterns: Novel methods and applications
Maruti, Sonia S. , Dawn Flick, E. , Bazelier, Marloes , De Vries, Frank , Huybrechts, Krista F. , Levy, Drew
, Roddam, Andrew , Dong, Wei
Pharmacoepidemiology and Drug Safety. 2011. 20():S267-S268.
HbA1c control pre and post an episode of diabetic ketoacidosis: An observational study in the General
Practice Research Database (GPRD)
Ambery, Phil D. , Beeby, Matthew , Abell, Jill E.
Diabetes. 2011. 60():A369.
Incidence of venous thromboembolism (VTE) in the medically-ill population - Vte epidemiology group
(VEG) study
Cohen, A.T. , Rietbrock, S. , Martinez, C.
Journal of Thrombosis and Haemostasis. 2011. 9():41.
Incidence of venous thromboembolism (VTE) in the general population - VTE epidemiology group (VEG) study
Martinez, C. , Rietbrock, S. , Bamber, L. , Cohen, A.T.
Journal of Thrombosis and Haemostasis. 2011. 9():41.
The impact of anticoagulant monitoring and control on recurrent venous thromboembolism and bleeding in routine clinical practice
Roskell, N.S. , Wolowacz, S.E. , Ziemiecki, R. , Gallagher, A.M. , Feuring, M. , Fraessdorf, M. , Hass, B.
Journal of Thrombosis and Haemostasis. 2011. 9():193.
Venous thromboembolism (VTE): Disease burden and outcomes - VTE epidemiology group (VEG) study
Martinez, C. , Rietbrock, S. , Bamber, L. , Cohen, A.T.
Journal of Thrombosis and Haemostasis. 2011. 9():749.

83.
84.
85.
86.
87.
88.
89.
90.
91.
92.
93.
94.
95.
96.
97.
98.
Risk factors for venous thromboembolism (VTE) in surgical patients in the VTE epidemiology group (VEG) study
Martinez, C. , Rietbrock, S. , Cohen, A.T.
Journal of Thrombosis and Haemostasis. 2011. 9():749-750.
Risk factors for venous thromboembolism (VTE) in medical patients in the VTE epidemiology group (VEG) study
Cohen, A.T. , Rietbrock, S. , Martinez, C.
Journal of Thrombosis and Haemostasis. 2011. 9():750.
Social risk factors for venous thromboembolism (VTE) in the VTE epidemiology group (VEG) study
Cohen, A.T. , Rietbrock, S. , Martinez, C.
Journal of Thrombosis and Haemostasis. 2011. 9():767.
The impact of antibiotic and mometasone furoate nasal spray therapy on healthcare resource utilisation among acute rhinosinusitis patients in the United Kingdom
Maiese, E. , De Moor, C. , McLaughlin, J. , Navaratnam, P.
Allergy: European Journal of Allergy and Clinical Immunology. 2011. 66():243.
Efficiency of the case-time-control design: Empirical evidence from a case-control study of methicillin resistant S. aureus (MRSA) and antibacterials in children
Schneider-Lindner, V. , Quach, C. , Hanley, J. , Suissa, S.
American Journal of Epidemiology. 2011. 173():S275.
Prevalence of diagnosed adult immune thrombocytopenia in the United Kingdom
Bennett, D. , Hodgson, M. , Shukla, A. , Logie, J.
Haematologica. 2011. 96():94.
Evaluation of baseline laboratory parameters potentially associated with thromboembolic events in patients with chronic ITP enrolled in a clinical trial of eltrombopag
Shamsi, T. , Wong, R. , Giagounidis, A. , Bakshi, K. , Brainsky, A.
Haematologica. 2011. 96():96.
Severe psoriasis impacts reclassification of ten-year framingham cardiovascular risk
Yu, Y. , Krishnamoorthy, P. , Pinnelas, R. , Shin, D.B. , Troxel, A.B. , Mehta, N.N. , Gelfand, J.M.
Journal of Investigative Dermatology. 2011. 131(6):1390.
Co-administration of statins with cytochrome P450 3A4 inhibitors in a UK primary care population
Ameet, Bakhai , Una, Rigney , Samuel, Hollis , Cathy, Emmas
Pharmacoepidemiology and Drug Safety. 2011. 20(6):661.
Risk of fracture in patients with Myasthenia Gravis: The general practice research database
Pouwels, S. , Javaid, M. , De Boer, A. , De Vries, F.
Bone. 2011. 48():S270.
Role of inhaled corticosteroid therapy in the real-world management of chronic obstructive pulmonary disease
Postma, D. , Colice, G. , Martin, R. , Barnes, N. , Roche, N. , Lee, A.J. , Dorinsky, P. , Burden, A. , Von
Ziegenweidt, J. , Hillyer, E.V. , Chisholm, A. , Price, D.
American Journal of Respiratory and Critical Care Medicine. 2011. 183(1):.
Description and frequency of exacerbations in a 12-month period among pediatric patients with asthma in the United Kingdom (UK) primary care setting
Suruki, R.Y. , Davis, K.J. , Ortega, H.G.
American Journal of Respiratory and Critical Care Medicine. 2011. 183(1):.
Real-world effectiveness of extrafine hydrofluoroalkane beclomethasone and fluticasone: United Kingdom and United States data compared
Colice, G. , Martin, R. , Barnes, N. , Roche, N. , Lee, A.J. , Dorinsky, P. , Polos, P. , Von Ziegenweidt, J. ,
Burden, A. , Chisholm, A. , Hillyer, E.V. , Price, D.
American Journal of Respiratory and Critical Care Medicine. 2011. 183(1):.
Suboptimal gastroprotective coverage of NSAID use and the risk of upper gastrointestinal complications
Van Soest, Eva M. , Valkhoff, Vera E. , Mazzaglia, Giampiero , Schade, Rene , Molokhia, Mariam ,
Goldstein, Jay L. , Hernandez-Diaz, Sonia , Trifiro, Gianluca , Dieleman, Jeanne , Kuipers, Ernst J. ,
Sturkenboom, Miriam C.
Gastroenterology. 2011. 140(5):S45.
Oesophageal cancer - An aetiological investigation into the potential protective effect of statins in the UK
General Practice Research Database (GPRD)
Bhutta, Hina Y. , Clark, Allan , Holt, Sean , Lewis, Michael P. , Hart, Andrew
Gastroenterology. 2011. 140(5):S166.
Adherence to gastroprotective agents and the risk of upper gastrointestinal complications in coxib users
Valkhoff, Vera E. , Van Soest, Eva M. , Mazzaglia, Giampiero , Schade, Rene , Molokhia, Mariam ,

99.
100.
101.
102.
103.
104.
105.
106.
107.
108.
109.
Goldstein, Jay L. , Hernandez-Diaz, Sonia , Trifiro, Gianluca , Dieleman, Jeanne , Kuipers, Ernst J. ,
Sturkenboom, Miriam C.
Gastroenterology. 2011. 140(5):S585.
Risk of community-acquired pneumonia in patients with a diagnosis of pernicious anemia
Almario, Christopher V. , Riff, Brian , Metz, David C. , Merriman, Nathan , Yang, Yu-Xiao
Gastroenterology. 2011. 140(5):S730.
Attributable risk estimate of severe psoriasis on major cardiovascular events
Faha, Nehal N. Mehta , Pinnelas, Rebecca , Krishnamoorthy, Parasuram , Yu, Yiding , Shin, Daniel , Troxel,
Andrea , Gelfand, Joel M.
Journal of the American College of Cardiology. 2011. 57(14):E486.
Migraine in patients with Rosacea
Spoendlin, J. , Jick, S. , Schneider, C. , Meier, C.
International Journal of Clinical Pharmacy. 2011. 33(2):405.
Antihypertensive drugs and the risk of developing Alzheimer’s disease
Imfeld, P. , Brauchli, Y.B. , Jick, S.S. , Meier, C.R.
International Journal of Clinical Pharmacy. 2011. 33(2):409.
What happens to HbA1c control in Type 1 diabetes patients exposed to a serious hypoglycaemic event? A retrospective observational study in the General Practice Research Database
Ambery, P.D. , Beeby, M. , Abell, J.
Diabetic Medicine. 2011. 28():55.
Association between practice size and quality of diabetes management in primary care
Vamos, E.P. , Bottle, A. , Hamilton, F.L. , Curcin, V. , Ng, A. , Molokhia, M. , Car, J. , Majeed, A. , Millett,
C.
Diabetic Medicine. 2011. 28():87.
Measurement of HbA1c control in proximity to a diabetic ketoacidosis event: A retrospective observational study in the General Practice Research Database
Ambery, P.D. , Beeby, M. , Abell, J.
Diabetic Medicine. 2011. 28():153.
Bisphosphonate use is associated with reduced revisions of lower limb joint (knee or hip) arthroplasty: A population-based cohort study
Prieto-Alhambra, Daniel , Javaid, M Kassim , Judge, Andrew , Murray, David W , Carr, Andrew J , Cooper,
Cyrus , Arden, Nigel K
Osteoporosis International. 2011. 22():S101-S102.
Effectiveness of mometasone furoate nasal spray with or without antibiotics vs. antibiotic monotherapy in patients with acute rhinosinusitis in the United Kingdom
Maiese, E.M. , De Moor, C. , Reardon, G. , McLaughlin, J. , Navar-Atnam, P.
Journal of Allergy and Clinical Immunology. 2011. 127(2):AB120.
Cause-specific mortality in patients with severe psoriasis: A population-based cohort study
Abuabara, Katrina , Neimann, Andrea , Troxel, Andrea , Shin, Daniel , Azfar, Rahat
Journal of the American Academy of Dermatology. 2011. 64(2):AB8.
Patterns of primary care consultation in children and young people prior to the diagnosis of cancer
Dommett, Rachel , Redaniel, Theresa , Hamilton, Willie , Martin, Richard , Stevens, Michael
Pediatric Blood and Cancer. 2011. 57(5):740-741.

1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
Hip/Knee Arthroplasty and Risk of Hip Fracture: A Population-Based Case-Control Study
Lalmohamed A, Arden N, van Staa TP, Leufkens HGM, de Vries F.
Pharmacoepidemiology and Drug Safety, 2010; 19: S27
Recruitment Strategy for Genetic Data Collection: The UK General Practice Research Database
Setakis E, de Vries F, Pirmohamed M, van Staa TP
Pharmacoepidemiology and Drug Safety, 2010; 19: S37
Linking UK Death Certificate Data to UK Primary Care Data (GPRD) To Obtain Cause of Death
Setakis E, Gallagher A, Williams TW, van Staa TP
Pharmacoepidemiology and Drug Safety, 2010; 19: S83
Use of Antidepressant Drugs and Risk ofOsteoporotic and Non-Osteoporotic Fractures: Focus on the
Affinity for the Serotonin Receptor
Verdel BM, Souverein PC, Egberts TC, van Staa TP, Leufkens HGM, de Vries F.
Pharmacoepidemiology and Drug Safety, 2010; 19: S121
Risk of Fracture in Patients with Multiple Sclerosis:The General Practice Research Database
Bazelier M, van Staa TO, Leufkens H, Vestergaard P, de Vries F.
Pharmacoepidemiology and Drug Safety, 2010; 19: S129
Characterics of Exposure to Non-Steroid Anti-Inflammatory Drugs in European Databases de Vries F, Kieler H, van Dijk L, Svensson T, van Staa TP
Pharmacoepidemiology and Drug Safety, 2010; 19: S174
Linking Primary Care Data (UK GPRD) to Hospital Records (HES)
Eaton S, Setakis E, Williams TW, van Staa TP
Pharmacoepidemiology and Drug Safety, 2010; 19: S195
Change in Drug Utilization Patterns in Statin Users with Increased Creatine Phosphokinase (CPK)
Levels de Vries F, Setakis E, van Staa TP
Pharmacoepidemiology and Drug Safety, 2010; 19: S206
Risk of Cataract in Patients with Multiple Sclerosis: A Population-Based Cohort Study
S Mu¨ ller-Schotte, M Bazelier, van Staa TP, Leufkens HGM, de Vries F
Pharmacoepidemiology and Drug Safety, 2010; 19: S259
Cause of Death in Patients with Multiple Sclerosis and Controls: The General Practice Research
Database
Lalmohamed A, Bazelier MT, van Staa TP
Pharmacoepidemiology and Drug Safety, 2010; 19: S276
Linking UK Death Certificate Data to UK Primary Care Data (General Practice Research Database)
Setakis E., Puri S, Gallagher A, Eaton S, De Vries F, Williams TW, van Staa TP. GPRD,
Pharmacoepidemiology and Drug Safety, 2010; 19: S310
Representativeness of Subset of the General Practice Research Database (GPRD) Linked to Other Data
Sources
Setakis E., Puri S, Williams TW.
Pharmacoepidemiology and Drug Safety, 2010; 19: S311
Incidence of thromboembolic events across eltrombopag clinical trials in chronic immune thrombocytopenia
(ITP)
Bussel, James B. , Cheng, Gregory , Saleh, Mansoor N. , Mayer, Bhabita , Vasey, Sandra Y. , Brainsky,
Andres

14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
Blood. 2010. 116(21):.
Incidence, prevalence and risk factors for death in epilepsy: A population cohort, nested case control study
Ridsdale, L. , Gulliford, M. , Richardson, M. , Charlton, J. , Ashworth, M.
Journal of Neurology, Neurosurgery and Psychiatry. 2010. 81(11):e47.
(Young Investigator Award) risk of fracture in patients with multiple sclerosis: A population-based cohort study
Bazelier, M. , Van Staa, T. , Leufkens, H. , Vestergaard, P. , Cooper, C. , Uitdehaag, B. , Lalmohamed, A. ,
De Vries, F.
Osteoporosis International. 2010. 21():S450-S451.
Comorbidity profiling of copd patients in the United Kingdom primary care using an incidence based approach to detect associations with the disease
Kiri, V.A.
Value in Health. 2010. 13(7):A318-A319.
Cost-effectiveness of extended-release nicotinic acid/laropiprant as monotherapy versus ezetimibe monotherapy in patients with mixed dyslipidaemia in Scotland
Jameson, K. , Davies, G.M. , Ambegaonkar, B.M. , Sazonov, V. , O'Regan, C.
Value in Health. 2010. 13(7):A354.
Health care utilization of patients with depression before and after intiating duloxetine
Shi, N. , Durden, E. , Cao, Z. , Torres, A. , Happich, M.
Value in Health. 2010. 13(7):A453.
Increased risk of hip and wrist fracture in patients with cirrhosis compared with the general population: A population-based cohort study
West, Joe , Asghar, Zahid , Aithal, Guruprasad P. , Card, Tim R. , Fleming, Kate
Hepatology. 2010. 52():895A.
Incidence of hepatocellular carcinoma among people with alcoholic and cryptogenic cirrhosis in the general population of the UK
Fleming, Kate , Card, Tim R. , Aithal, Guruprasad P. , West, Joe
Hepatology. 2010. 52():913A.
Diabetes and pancreatitis: A population based study to determine the prevalence and incidence of pancreatitis in people with and without diabetes
Mani, H. , Thakrar, B. , Davies, M.J. , Khunti, K.
Diabetologia. 2010. 53():S67-S68.
Increased risk of acute renal failure in patients with type 2 diabetes compared to those without diabetes
Brodovicz, K.G. , Girman, C.J. , Kou, T.D. , Engel, S.S. , Katz, L. , Alexander, C.M. , Williams-Herman,
D.E.
Diabetologia. 2010. 53():S167.
Exposure to teratogenic drugs and concomitant contraception in women of child-bearing age with type 2 diabetes: A population based cohort study
Webster, D.A. , Khunti, K. , Wilmot, E.G. , Thakrar, B. , Davies, M.J. , Anwar, A.
Diabetologia. 2010. 53():S434.
Macrovascular complications may be associated with tighter glycaemic control in patients with type 1 diabetes: An analysis of primary care data in the UK
Edson, E.J. , Le, T.K. , Nelson, D.R. , Haldane, D. , Mendelsohn, A.B. , Pillemer, S. , Curtis, B.H.
Diabetologia. 2010. 53():S504.
Risk factors for stroke in 79,884 atrial fibrillation patients in primary care in the United Kingdom
Lane, D.A. , Van Staa, T.P. , Setakis, E. , Di Tanna, G.L. , Lip, G.Y.H.
European Heart Journal. 2010. 31():154.
Optimal warfarin anticoagulation and the prevention of stroke in patients with atrial fibrillation: A population-based study
Azoulay, L. , Simon, T. , Dell'aniello, S. , Renoux, C. , Suissa, S.
European Heart Journal. 2010. 31():155.
Hypoglycemic agents and the risk of cancer
Zhang, Hui , Tarek, Hammad A. , Christiani, David C. , Giovannuci, Edward
Pharmacoepidemiology and Drug Safety. 2010. 19():S1-S2.
Validation of cancer diagnoses recorded in the general practice research database
Zhang, Hui , Hammad, Tarek A. , Giovannuci, Edward , Kang, Elizabeth , Christiani, David C.
Pharmacoepidemiology and Drug Safety. 2010. 19():S11-S12.
Factors predictive of H1N1 influenza vaccine uptake among 'At-Risk' patients in the UK general practice research database
Sammon, Cormac , McGrogan, Anita , Snowball, Julia

30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
Pharmacoepidemiology and Drug Safety. 2010. 19():S13-S14.
Risk of lung cancer in users of estradiol/dydrogesterone or other HRT preparations
Schneider, Cornelia , Jick, Susan S. , Meier, Christoph R.
Pharmacoepidemiology and Drug Safety. 2010. 19():S26.
EARTH-epidemiology of atherosclerotic disease in the UK: Evidence of reducing incidence of cardiovascular disease (CVD), particularly coronary heart disease, in the UK adult population between 1999 and 2008
Shafe, Anna , Lee, Sally , Cowie, Martin
Pharmacoepidemiology and Drug Safety. 2010. 19():S30.
Serum sodium concentration monitoring and hyponatremia in thiazide-treated patients
McDowell, Sarah E. , Coleman, Jamie J. , Evans, Stephen J.W. , Ferner, Robin E.
Pharmacoepidemiology and Drug Safety. 2010. 19():S40-S41.
Body mass index and the incidence of influenza-associated complications in a UK population
Blumentals, William A. , Nevitt, Alan , Huang, Liping , Peng, Michael M. , Toovey, Stephen
Pharmacoepidemiology and Drug Safety. 2010. 19():S41.
Co-prescribing of medications with anticholinergic properties to those using cholinesterase inhibitors for dementia
Bloomfield, Katherine , John, Nick , McGrogan, Anita , Jones, Roy , De Vries, Corinne
Pharmacoepidemiology and Drug Safety. 2010. 19():S48.
Potential diagnostic/ascertainment bias associated with endoscopic findings among bisphosphonates users
Lubwama, Robert N. , Kou, Tzuyung D. , Chandler., Julie
Pharmacoepidemiology and Drug Safety. 2010. 19():S60-S61.
Influenza and the incidence of acute pancreatitis in a UK population
Blumentals, William A. , Nevitt, Alan , Huang, Liping , Peng, Michael M. , Abelardo, M. Connie
Pharmacoepidemiology and Drug Safety. 2010. 19():S62.
Treatment of diabetes before and during pregnancy
McGrogan, Anita , Snowball, Julia , De Vries., Corinne
Pharmacoepidemiology and Drug Safety. 2010. 19():S66-S67.
Potential ascertainment bias in assessment of obesity and smoking history and its impact on type 2 diabetes disease in the general practice research database
Kou, Tzuyung D. , Brodovicz, Kimberly G. , Alexander, Charles , Katz, Leonid , Girman, Cynthia J.
Pharmacoepidemiology and Drug Safety. 2010. 19():S109.
Adherence to proton pump inhibitors and the risk of upper gastrointestinal complications in coxib users
Valkhoff, V. , Van Soest, E. , Mazzaglia, G. , Schade, R. , Molokhia, M. , Dieleman, J. , Sturkenboom, M.
Pharmacoepidemiology and Drug Safety. 2010. 19():S110.
Hemoglobinuria, hemoglobinemia, and renal impairment in ITP patients
Xue, Fei , Wentworth, Chuck , Ganesh, Vanitha , Gastanaga, Victor , Hughes, Gail , Stryker, Scott , Cha,
Steven , Zhao, Sean
Pharmacoepidemiology and Drug Safety. 2010. 19():S119-S120.
Recording of pregnancy losses on the general practice research database
Charlton, Rachel , Snowball, Julia , Weil, John , Cunnington, Marianne , De Vries, Corinne
Pharmacoepidemiology and Drug Safety. 2010. 19():S122.
The use of observed vs expected analyses in real-time vaccine safety surveillance in the UK during the
H1N1 pandemic
Seabroke, Suzie , Bryan, Philip , Wise, Lesley
Pharmacoepidemiology and Drug Safety. 2010. 19():S188.
Pregnancy loss in patients with type 1 or type 2 diabetes during pregnancy
McGrogan, Anita , Snowball, Julia , De Vries, Corinne
Pharmacoepidemiology and Drug Safety. 2010. 19():S211.
Diuretic use and the risk of gastrointestinal bleeding in the United Kingdom general population
Delaney, Joseph A.C. , Bitton, Alain , Suissa, Samy
Pharmacoepidemiology and Drug Safety. 2010. 19():S216.
Adherence to gastroprotective agents and the risk of upper gastrointestinal complications in NSAID users
Van Soest, E. , Valkhoff, V. , Mazzaglia, G. , Schade, R. , Molokhia, M. , Dieleman, J. , Sturkenboom, M.
Pharmacoepidemiology and Drug Safety. 2010. 19():S219.
Using inverse probability weighting to estimate warfarin adverse effects: Concerns with large and variable inverse probability weights
Delaney, Joseph A.C. , Platt, Robert W. , Suissa, Samy
Pharmacoepidemiology and Drug Safety. 2010. 19():S227.
Prevalence of co-morbidities and drug exposure in patients with Alzheimer's disease around the time

48.
49.
50.
51.
52.
53.
54.
55.
56.
57.
58.
59.
60.
61.
62.
63. of diagnosis
Imfeld, Patrick , Brauchli, Yolanda B. , Schuerch, Markus , Meier, Christoph R.
Pharmacoepidemiology and Drug Safety. 2010. 19():S236.
Antibacterial drugs and the risk of community-associated methicillin resistant staphylococcus aureus (C-
MRSA) in children
Schneider-Lindner, Verena , Quach, Caroline , Hanley, James A. , Suissa, Samy
Pharmacoepidemiology and Drug Safety. 2010. 19():S239-S240.
Elevated risk for acute pancreatitis in type 2 diabetes patients compared to those without diabetes
Kou, Tzuyung D. , Cai, Bing , Alexander, Charles M. , Williams-Herman, Debora , Katz, Leonid , Girman,
Cynthia J.
Pharmacoepidemiology and Drug Safety. 2010. 19():S254.
Colorectal cancer incidence on the GPRD
Charlton, Rachel , Snowball, Julia , De Vries, Corinne
Pharmacoepidemiology and Drug Safety. 2010. 19():S262-S263.
Reflux disease, gastrointestinal ulcer or weight loss in patients with COPD
Schneider, Cornelia , Jick, Susan S. , Bothner, Ulrich , Meier, Christoph R.
Pharmacoepidemiology and Drug Safety. 2010. 19():S295.
Diabetes mellitus and risk of gallstone disease followed by cholecystectomy
Imfeld, Patrick , Bodmer, Michael , Brauchli, Yolanda B. , Krähenbühl, Stephan , Jick, Susan S. , Meier,
Christoph R.
Pharmacoepidemiology and Drug Safety. 2010. 19():S295-S296.
Risk of incident autoimmune diseases after hepatitis B vaccination - A large cohort study in the GPRD
Egbring, Marco , Kullak-Ublick, Gerd A. , Russmann, Stefan
Pharmacoepidemiology and Drug Safety. 2010. 19():S323.
Comparative evaluation of desloratadine versus sedating antihistamines in managing rhinitis patients with comorbid asthma or chronic urticaria in the United Kingdom
De Moor, C. , McLaughlin, J. , Reardon, G. , Navaratnam, P.
Allergy: European Journal of Allergy and Clinical Immunology. 2010. 65():153-154.
Comparative analysis of desloratadine and levocetirizine in the management of chronic urticaria in the
United Kingdom
De Moor, C. , McLaughlin, J. , Reardon, G. , Navaratnam, P.
Allergy: European Journal of Allergy and Clinical Immunology. 2010. 65():458-459.
Causal effects of cox-2 selective inhibitors relative to non-selective non-steroid antiinflammatory drugs on gastrointestinal bleeding and acute myocardial infarction: An instrumental variable analysis
Davies, N.M. , Davey-Smith, G. , Windmeijer, F. , Martin, R.M.
American Journal of Epidemiology. 2010. 171():S101.
Association between change in HDL and vascular events in statin treated patients: Report from the UK general practice research database
Bash, L. , Ambegaonkar, B. , Wenworth, C. , May, C.
Atherosclerosis Supplements. 2010. 11(2):42.
Longitudinal assessment of dyslipidemia among patients treated with lipid modifying therapy in UK clinical practice
Ambegaonkar, B. , Eaton, S. , Jameson, K. , Amber, V. , Durrington, P.
Atherosclerosis Supplements. 2010. 11(2):78.
Suicide attempt in epilepsy: Incidence and risk factors
Hesdorffer, D.C. , Ishihara, L. , Mynelpalli, L. , Webb, D.J. , Weil, J. , Hauser, W.A.
Epilepsia. 2010. 51():30.
Cancer risk in people with epilepsy using valproate-sodium
Singh, G. , Bell, G. , Sander, J.W.
Epilepsia. 2010. 51():153.
Low recordings of spirometry values in patients with COPD despite nice guidelines in UK primary care setting
Suruki, R. , East, L. , Cockle, S. , Sampson, T. , Davis, K. , Price, D.
American Journal of Respiratory and Critical Care Medicine. 2010. 181(1):.
Mortality rates in COPD patients with cardiovascular disease in the UK
Miller, D.P. , Sampson, T. , Kaminski, J. , Davis, K.
American Journal of Respiratory and Critical Care Medicine. 2010. 181(1):.
Use of contraception by women with type 1 or type 2 diabetes mellitus
Shawa, J. , Smith, P.A.
European Journal of Contraception and Reproductive Health Care. 2010. 15():84-85.

64.
65.
66.
67.
68.
69.
70.
71.
72.
73.
Risk of myocardial infarction in ulcerative colitis and Crohn's disease
Osterman, Mark T. , Yang, Yu-Xiao , Brensinger, Colleen M. , Lichtenstein, Gary , Lewis, James D.
Gastroenterology. 2010. 138(5):S198.
Use of depot medroxyprogesterone acetate and fracture risk
Meier, C. , Kraenzlin, M.E. , Meier, C.R. , Brauchli, Y.B. , Jick, S.S.
Osteoporosis International. 2010. 21():S10.
A novel methodology for measuring the influence of comorbidity in health outcome studies
Kiri, V.A. , MacKenzie, G.
Value in Health. 2010. 13(3):A196.
Patterns of health service use in families where children enter public care: A nested case-control study using the general practice research database
Simkiss, D. , Spencer, N. , Stallard, N. , Thorogood, M.
Archives of Disease in Childhood. 2010. 95():A6.
Cause-specific mortality in severe psoriasis: A cohort study using the general practice research database
Abuabara, K. , Azfar, R.S. , Shin, D.B. , Neimann, A.L. , Troxel, A.B. , Gelfand, J.M.
Journal of Investigative Dermatology. 2010. 130():S63.
Warfarin, aspirin, and their combination in the prevention of stroke in patients with atrial fibrillation: A nested case-control study
Azoulay, Laurent , Simon, Teresa , DellAniello, Sophie , Suissa, Samy
Stroke. 2010. 41(4):e215-e216.
Toward automating an inference model on unstructured terminologies: Oxmis case study
Painter, Jeffery L.
Advances in Experimental Medicine and Biology. 2010. 680():645-651.
Treatment of type 2 diabetes and outcomes in patients with heart failure: A nested case control study from the United Kingdom general practice research database
Eurich, Dean T. , Macdonald, Michael R. , Majumdar, Sumit R. , Lewsey, James D. , Bhagra, Sai , Jhund,
Pardeep S. , Petrie, Mark C. , Mcmurray, John J. V. , Mcalister, Finlay A.
Diabetes. 2010. 70th Scientific Sessions of the American Diabetes Association
Characteristics of patients with depression in the UK initiating treatment with duloxetine and venlafaxine
XR
Durden, E. , Happich, M. , Shi, N. , Torres, A.
European Psychiatry. 2010. 25():.
Are general practitioners managing more patients with sexually transmitted infections: Trends in diagnoses and treatment from 2000-2008
Wetten, S. , Yung, M. , Hughes, G.
HIV Medicine. 2010. 11():44.
1.
2.
3.
Prior Event Ratio Adjustment: A magic bullet or more of the same?
Gallagher A, MSC, deVries Frank, PhD and vanStaa Tjeerd
Pharmacepidemiology Drug Safety 2009: 18 ;S1-S273.
032
Outcomes following a hip fracture and length of hospitalisation: the General Practice Database.
Gallagher A, deVries Frank, Ariely Rinat, vanStaa Tjeerd.
Long-Acting-beta2-agonists in Audit asthma and the pattern of risk of death and severe asthma outcomes:
A study with the UK General Practice Database (GPRD)
Zhang Bill, DeVries Frank, Setakis Efrosini, VanStaa Tjeerd.
Pharmaco Drug Safety 2009: 18;S1-S273: 594
Initiation and persistence of warfarin or aspirin treatments in chronic atrial fibrillation: do the

4. appropriatre patients receive stroke prophylaxis?
Gallagher A, Rietbrock S, Plumb J, VanStaa T.
How effective are dose-adjusted warfarin and aspirin for the prevention of stroke in patients with chronic
5.
6. atrial fibrillation? An analysis of the General Practice Database.
Gallagher A, Rietbrock S, Plumb J, VanStaa T.
Chronic atrial fibrillation: incidence, Prevalence and prediction of stroke using the CHAD
2
Risk stratification scheme .
Gallagher AM, Rietbrock S, Heeley E, Plumb J, VanStaa T.
7.
8.
9.
The contribution and persistence and compliance with bisphosphonates on fracture outcomes.
Rietbrock S, Olsen M, VanStaa TP.
Benefit harm modelling: what is this and what can it contribute to pharmacovigilance?
VanStaa T, Lynd LD, Leufkens Hubert GM, Raine J, Petri H.
The pattern of risk of myocardial infarction in ptients taking asthma medication: A study with UK
General Practice Database
Zhang B, DeVries F, Setakis E Vanstaa TP
10.
Pharmaco Drug Safety 2009: 18 ;S1-S273: 481
Assessment of Data Quality in Health Care Databases
Juszczak, Williams T, VanStaa T,
11.
Pharmaco Drug Safety 2009: 18:: S1-S273 :422
Use of Dopaminergic Drugs and risk of hip or femur fracture: A population case-control study.
Arbouw M, Movig K, Vanstaa T, deVries F et.a.
12.
Pharmaco Drug Safety 2009: 18:: S1-S273 :464
Methodological and Regulatory challenges in the Assessment of long term drug safety
De Bruin ML, VanStaa TP, et al.
13.
Pharmaco Drug Safety 2009: 18:: S1-S273 :397
Evaluation of the level of anticoagulation control in patients with non-valvular atrial fibrillation
Zhang,B, Setakis E, vanStaa TP
Pharmaco Drug Safety 2009: 18:: S1-S273 :265
14. Use of proton pump inhibitors and risk of hip fracture
Lalmohamed A, Pouwels S, Cooper C, VanStaa T, deVriesF, Leufkens B
Pharmaco Drug Safety 2009: 18:: S1-S273 :039
15. Use of Organic nitrates and the risk of hip fracture: A population based case-control study
Lalmohamed A, Pouwels S, Cooper C, VanStaa T, deVriesF, Leufkens B, et al
Pharmaco Drug Safety 2009: 18:: S1-S273 :018
16. Risks of mortality and stroke associated with sub-optimally anticoagulated atrial fibrillation patients
Setakis E, Zhang B, VanStaa TP
Pharmaco Drug Safety 2009: 18:: S1-S273 :509
17. Insomnia as a predictor of depression in UK primary care de Vries F: Gallagher AM; Lader MH; Tylee AT; Donoghue J; Cockle SM; vanStaa TP, Nutt DJ.
European Neuropsychopharmacology 2009( 19 )S372-S373
18. Resource use in depressed patients with sleep disturbance
Gallagher, AM; deVries F; Nutt DJ; Donoghue J; Tylee AT, Cockle SM; vanStaa TP; Lader MH.
European Neuropsychopharmacology 2009( 19 )S 378-S379
19. Initiation of hypnotics or anxiolytics in depressed patients with sleep disturbance
Gallagher, AM; deVries F; Nutt DJ; Donoghue J; Tylee AT, Cockle SM; vanStaa TP; Lader MH.
European Neuropsychopharmacology 2009( 19 )S379

20. The risk of suicide and suicidal ideation in depressed patiens with sleep disturbance.
Gallagher, AM; deVries F; Nutt DJ; Donoghue J; Tylee AT, Cockle SM; vanStaa TP; Lader MH.
European Neuropsychopharmacology 2009( 19 )S380
21. Persistance with hypnotics in depressed patients treated in UK primary care.
Gallagher, AM; deVries F; Nutt DJ; Donoghue J; Tylee AT, Cockle SM; vanStaa TP; Lader MH.
European Neuropsychopharmacology 2009( 19 )S381
22. The CAPER studies: five case-control studies aimed at identifying and quantifying the risk of cancer in symptomatic primary care patients.
Hamilton W.
British Journal of Cancer. 2009:S80 – S6.
23.
24.
25.
26.
A comparison of the sex-specific incidence of immune thrombocytopenia in children, teenagers, and adults in the general practice research database
Yong, Mellissa , Schoonen, W. Marieke , Li, Lin , Kaye, James A.
Blood. 2009. 114(22):.
Epilepsy and psychiatric disorders: Evidence for a bidirectional relationship
Hesdorffer, Dale C. , Ishihara-Paul, L. , Mynepalli, L. , Webb, D.J. , Weil, J. , Hauser, W.A.
Epilepsia. 2009. 50():220-221.
Risk of incident autoimmune diseases after hepatitis b vaccination - A large cohort study in the UK general practice research database
Egbring, M. , Ceschi, A. , Kullak-Ublick, G.A. , Russmann, S.
British Journal of Clinical Pharmacology. 2009. 68():8.
Phynx: An open source software solution supporting web-based patient-level data review for drug safety database studies
Egbring, M. , Kullak-Ublick, G.A. , Russmann, S.
British Journal of Clinical Pharmacology. 2009. 68():44.
Mortality following antiepileptic drug use in children and adolescents
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
Besag, F. , Ackers, R. , Hughes, E. , Squier, W. , Wong, I.
Epilepsia. 2009. 50():152.
Off-label prescribing of inhaled corticosteroid/ Long acting beta-agonist combination products in copd patients
Rigney, U. , Emmas, C. , Morais, J.
Value in Health. 2009. 12(7):A307.
Health economic comparison of outpatient management of fibromyalgia before and after diagnosis in five
European Countries
Lamotte, M. , Maugars, Y. , Le Lay, K. , Taieb, C.
Value in Health. 2009. 12(7):A438.
Costs avoided by diagnosing fibromyalgia
Lamotte, M. , Maugars, Y. , Le Lay, K. , Taieb, C.
Value in Health. 2009. 12(7):A438.
Persistence with beta-blockers in coronary heart disease patients in UK primary care
Setakis, E. , Morley, C. , Cockle, S. , Van Staa, T.P. , Kassianos, G.
European Heart Journal. 2009. 30():303-304.
Beta-blocker doses in coronary heart disease patients treated in UK primary care
Setakis, E. , Kassianos, G. , Cockle, S. , Van Staa, T.P. , Morley, C.
European Heart Journal. 2009. 30():511.
Adverse events and subsequent changes in beta-blocker treatment in coronary heart disease patients in UK primary care
Setakis, E. , Kassianos, G. , Cockle, S. , Van Staa, T.P. , Morley, C.
European Heart Journal. 2009. 30():974.
Cardiovascular risk profile and blood pressure control in diabetic hypertension patients treated in primary care practices
Wu, D. , Phatak, H. , Wentworth, C.
European Heart Journal. 2009. 30():1035-1036.
Record-linkage for Research
Macdonald, T.
Basic and Clinical Pharmacology and Toxicology. 2009. 105():14.
Statins, other antihyperlipidemic agents, and psoriasis
Brauchli, Yolanda B. , Jick, Susan S. , Meier, Christoph R.

37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
Pharmacoepidemiology and Drug Safety (PDS). 2009. 18(S1):S6.
Risk of cardiovascular outcomes in users of estradiol/dydrogesterone or other HRT preparations
Schneider, Cornelia , Jick, Susan S. , Meier, Christoph R.
Pharmacoepidemiology and Drug Safety (PDS). 2009. 18(S1):S11.
Can the general practice research database identify a known teratogenic association?
Charlton, Rachel A. , Weil, John G. , Snowball, Julia M. , Cunnington, Marianne C. , De Vries, Corinne S.
Pharmacoepidemiology and Drug Safety (PDS). 2009. 18(S1):S12.
The risk of cancer associated with anti-diabetic agents
Zhang, Hui-Talia , Hammad, Tarek A. , Christiani, David , Giovannuci, Edward
Pharmacoepidemiology and Drug Safety (PDS). 2009. 18(S1):S39.
Exploratory analysis of the relationship between antipsychotic use and the incidence of seizures among patients with schizophrenia in the UK General Practice Research Database (GPRD)
Jones, Meghan E. , Rizvi, Lamiya A. , Strombom, Indiana , DeLisle, Frank , Kryzhanovskaya, Ludmila ,
Wernicke, Joachim , Kinon, Bruce J.
Pharmacoepidemiology and Drug Safety (PDS). 2009. 18(S1):S42.
Heart failure, myocardial infarction and lung cancer in patients with chronic obstructive pulmonary disease
Rodríguez, Luis A García , Wallander, Mari-Ann , Martín-Merino, Elisa , Johansson, Saga
Pharmacoepidemiology and Drug Safety (PDS). 2009. 18(S1):S49-S50.
Utilisation of psychotropic medicines in pregnancy
Terzakis, Irini-Alexia , Snowball, Julia M. , McGrogan, Anita , De Vries, Corinne S.
Pharmacoepidemiology and Drug Safety (PDS). 2009. 18(S1):S78.
Population-based studies of antithyroid drugs and sudden cardiac death
Van Noord, Charlotte , Sturkenboom, Miriam C.J.M. , Straus, Sabine M.J.M. , Witteman, Jacqueline C.M. ,
Stricker, Bruno H.C.
Pharmacoepidemiology and Drug Safety (PDS). 2009. 18(S1):S115.
Risk of incident atrial fibrillation in users of antihypertensive drugs
Schaer, Beat A. , Schneider, Cornelia , Jick, Susan S. , Conen, David , Osswald, Stefan , Meier, Christoph R.
Pharmacoepidemiology and Drug Safety (PDS). 2009. 18(S1):S126-S127.
Ventricular arrhythmia and sudden unexpected death and domperidone
Van Noord, Charlotte , Dieleman, Jeanne P. , Verhamme, Katia , Sturkenboom, Miriam C.J.M.
Pharmacoepidemiology and Drug Safety (PDS). 2009. 18(S1):S155.
COPD classification based on medical codes and spirometry - A comparison
Suruki, Robert Y. , Muellerova, Hana , Baxter, Richard , Davis, Kourtney J.
Pharmacoepidemiology and Drug Safety (PDS). 2009. 18(S1):S188.
Availability of spirometry records in patients with COPD in the general practice research database
Suruki, Robert Y. , Muellerova, Hana , Baxter, Richard , Davis, Kourtney J.
Pharmacoepidemiology and Drug Safety (PDS). 2009. 18(S1):S188-S189.
Combination therapy of sulfonylureas and metformin and the risk of death in patients with type 2 diabetes
Azoulay, Laurent , Schneider-Lindner, Verena , Dell'Aniello, Sophie , Schiffrin, Alicia , Suissa, Samy
Pharmacoepidemiology and Drug Safety (PDS). 2009. 18(S1):S195.
Is persistence fading? Time trends and determinants of antibiotic prescriptions in the community for children in the United Kingdom 1993-2007
Schneider-Lindner, V. , Dell'Aniello, S. , Kezouh, A. , Quach, C. , Hanley, J. , Suissa, S.
Pharmacoepidemiology and Drug Safety (PDS). 2009. 18(S1):S195.
Use of antiepileptic drugs in epilepsy and the risk of self harm and suicidal behaviour
Andersohn, Frank , Schade, René , Martinez, Carlos , Willich, Stefan N. , Garbe, Edeltraut
Pharmacoepidemiology and Drug Safety (PDS). 2009. 18(S1):S201.
Renal outcomes in people with bipolar disorder treated with lithium: A retrospective cohort database study
Reilly, Joe , Close, Helen , Main, John , Kripalani, Mukesh , Hungin, Pali , Wilson, Douglas , Mason, James
Pharmacoepidemiology and Drug Safety (PDS). 2009. 18(S1):S202.
An updated cohort study on the risk of cholestatic liver disease and flucloxacillin using data from the UK general practice research database
Li, Lin , Jick, Hershel , Jick, Susan S.
Pharmacoepidemiology and Drug Safety (PDS). 2009. 18(S1):S215.
The risk of depression in patients with psoriasis
Kurd, Shanu K. , Troxel, Andrea B. , Gelfand, Joel M.
Pharmacoepidemiology and Drug Safety (PDS). 2009. 18(S1):S227-S228.
Renal impairment among adult ITP patients: Use of GPRD for proactive safety surveillance
Gastanaga, Victor , Wentworth, Chuck , Yeo, Anthony , Hughes, Gail , Cha, Steven , Zhao, Sean
Pharmacoepidemiology and Drug Safety (PDS). 2009. 18(S1):S250-S251.

54.
55.
56.
57.
58.
59.
60.
61.
62.
63.
64.
65.
66.
67.
68.
69.
70.
71.
SERETIDE and risk of incident non-vertebral fractures among COPD patients in the UK
Miller, David P. , Davis, Kourtney J.
Pharmacoepidemiology and Drug Safety (PDS). 2009. 18(S1):S257.
Effectiveness of mometasone furoate compared with oral antihistamines therapy for rhinitis and asthma
David, P. , Sims, E. , Kemp, L. , Von Ziegenweidt, J. , Navaratnam, P. , Gopalan, G.
Allergy: European Journal of Allergy and Clinical Immunology. 2009. 64():182.
Establishing the sequential progression of multiple allergic diagnoses in a retrospective birth cohort
Punekar, Y. , Sheikh, A.
Allergy: European Journal of Allergy and Clinical Immunology. 2009. 64():329.
Bimodal mortality risk in Wegener's granulomatosis
Luqmani, Raashid , Edwards, Chris , Culliford, David , Maskell, Joe , Arden, Nigel
APMIS. 2009. 117():160.
Medical contraindications for Splenectomy among adults with immune thrombocytopenic purpura: Data from the general Practice Research Database
Schoonen, W.M. , Li, L. , Fryzek, J.P. , Kaye, J.A.
Haematologica. 2009. 94():96-97.
Patterns of use of tamoxifen and aromatase inhibitors: A population-based observational study
Huiart, L. , Dell'Aniello, S. , Suissa, S.
Journal of Clinical Oncology. 2009. 27(15):556.
A case control study of risk factors for perforated diverticular disease
Humes, David J. , West, Joe , Fleming, Kate M. , Spiller, Robin C.
Gastroenterology. 2009. 136(5):A371-A372.
Is the menopause still aworkload issue in UK general practice? A retrospective analysis of the general practice research database
Iversen, L. , Delaney, E. , Hannaford, P. , Black, C.
Maturitas. 2009. 63():S69.
Smoking and amyotrophic lateral sclerosis: A prospective study
Alonso, A. , Logroscino, G. , Jick, S. , Hernán, M.
Neuroepidemiology. 2009. 33(1):72.
Cost-effectiveness of escitalopram versus venlafaxine in second-line treatment of major depressive disorder
(MDD) in Sweden
Despiégel, N. , Danchenko, N. , Maman, K.
Value in Health. 2009. 12(3):A177.
Risk of cardiovascular mortality in patients with severe psoriasis
Azfar, R.S. , Neimann, A.L. , Shin, D.B. , Troxel, A.B. , Gelfand, J.M.
Journal of Investigative Dermatology. 2009. 129():S63.
Bimodal mortality risk in Wegener's granulomatosis
Luqmani, Raashid A. , Edwards, Christopher , Culliford, David , Maskell, Joe , Jayne, David , Arden, Nigel
Rheumatology. 2009. 48():i16.
NSAID use before and after 28068 hip and 23634 knee arthroplasties: Results from the UK general practice research database
Maskell, Joe , Culliford, David , Mullee, Mark , Azagra, Rafael , Javaid, Muhammad , Arden, Nigel
Rheumatology. 2009. 48():i99.
Obesity is associated with poorer clinical outcomes following insulin initiation for patients with type 2 diabetes
Kumar, S. , Wilson, B. , Watson, L. , Alsop, J.
Diabetologia. 2009. 52(S1):S132-S133.
Predictors of drug choice in newly diagnosed type 2 diabetes
Hutchison, A. , Russell-Jones, D. , De Vries, C.S.
Diabetologia. 2009. 52(S1):S133.
Obesity increases healthcare resource use in patients with type 2 diabetes: A UK database analysis
Wilson, B.P. , Watson, L. , Alsop, J. , Kumar, S.
Diabetologia. 2009. 52(S1):S407.
Risk of incident autoimmune diseases after hepatitis b vaccination: A large cohort study in the U.K. general practice research database
Egbring, M. , Ceschi, A. , Kullak-Ublick, G.A. , Russmann, S.
Drug Safety. 2009. 32(10):899-900.
Phynx: An open-source software solution supporting web-based patient-level data review for drug safety database studies
Egbring, M. , Kullak-Ublick, G.A. , Russmann, S.

Drug Safety. 2009. 32(10):900.
72.
73.
74.
75.
76.
77.
78.
79.
The relationship between baseline testing of serum electrolytes and creatinine and adverse outcomes in patients treated with antihypertensive drugs: An analysis using propensity score matching methods
McDowell, S.E. , Coleman, J.J. , Evans, S.J.W. , Ferner, R.E.
Drug Safety. 2009. 32(10):912.
Non-cardiovascular drugs that inhibit hERG-encoded potassium channels and risk of sudden cardiac death
Van Noord, Charlotte , Sturkenboom, Miriam C.J.M. , Straus, Sabine M.J.M. , Witteman, Jacqueline C.M. ,
Stricker, Bruno H. Ch.
Drug Safety. 2009. 32(10):956.
Population-based studies of anti-thyroid drugs and sudden cardiac death
Van Noord, Charlotte , Sturkenboom, Miriam C.J.M. , Straus, Sabine M.J.M. , Hofman, Albert , Witteman,
Jacqueline C.M. , Stricker, Bruno H. Ch.
Drug Safety. 2009. 32(10):956-957.
Tranexamic acid and retinal vein occlusion
Shafe, A. , Wise, L. , Petersen, J.
Drug Safety. 2009. 32(10):961-962.
A case-control study to investigate the association between finasteride and male breast cancer using the GPRD
Seabroke, S. , Irvine, D. , Wise, L.
Drug Safety. 2009. 32(10):963-964.
Incidence rate and prevalence of obsessive compulsive disorder in treatment-seeking primary care patients
Veldhuis, J.H. , Wohlfarth, T. , Dieleman, J. , Storosum, J.G. , Van Den Brink, W. , Sturkenboom, M.C.J.M. ,
Denys, D.J.A.P.
European Neuropsychopharmacology. 2009. 19():S333.
Risk of incident autoimmune diseases after hepatitis B vaccination - A large cohort study in the UK General
Practice Research Database
Egbring, Marco , Ceschi, Alessandro , Kullak-Ublick, Gerd A. , Russmann, Stefan
Hepatology. 2009. 50():499A.
Malignancies in the abatacept rheumatoid arthritis clinical development program: An updated epidemiological assessment with >10,000 person-years of exposure
Lacaille, D. , Smitten, A. , Simon, T. , Qi, K. , Suissa, S. , Askling, J. , Franklin, J. , Hochberg, M.C. , Wolfe,
F.
Journal of Rheumatology. 2009. 36(11):2569.
1.
2.
3.
4.
Outcomes following a hip fracture and length of hospitalization
De Vries F, Gallagher A, Ariely R, van Staa T.
Pharmo
Last menstrual period estimation techniques compared to physician recorded last menstrual period dates in the GPRD.
Devine ST, Hammad TA.
Pharmacoepidemiology & Drug Safety:2008; 17 :S228
GPRD Study of pregnancy outcomes following the prescribing of DMARDs.
Vroom F, Snowball J, McGrogan A, de Jong-van Berg L, deVries C.
Pharmacoepidemiology & Drug Safety:2008; 17 :S227
Changes in the characteristics of patients prescribed selective Cox-2 inhibitors after the 2004 withdrawal of
Rofecoxib.
Setakis E, Leufkens HGM, vanStaa T.
Pharmacoepidemiology & Drug Safety:2008; 17 :S9

5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
The feasibility of linking the English Hospital Episode Statistics to the GPRD.
Eaton SC, Williams TJ, Puri S, vanStaa T.
Pharmacoepidemiology & Drug Safety:2008; 17 :S214
Benefit-Harm Modelling: What is this and what can it contribute to Pharmacovigilance?
Van Staa TP, Lynd LD, Leufkens GM, Raine J, Petri H.
Effect of antibiotics for Otitis Media on mastoiditis in children: Retrospective Cohort Study using the UK
GPRD.
Thompson PL, Gilbert R, Long P, Saxena S, Sharland M, Wong I.
Pharmacoepidemiology & Drug Safety:2008; 17 :S209
Mortality following antiepileptic drugs in paediatrics with epilepsy – preliminary results using the GPRD.
Ackers R, Besag FMC, Wong ICK,
Pharmacoepidemiology & Drug Safety:2008; 17 :S9
Outcomes evaluation following 12 month treatment with once daily tiotropium compared with four times daily Ipratropium/salbutamol: A GPRD study on patients with COPD .
Griffin J. Lee S, Caiado M, Price D, Kesten S
Pharmacoepidemiology & Drug Safety:2008; 17 :S183
A review of Post-Marketing safety studies submitted to the UK Regulator from 1993-2005
Shafe ACE, Wise L, Waller P.
Pharmacoepidemiology & Drug Safety:2008; 17 :S179
An analysis of glitazone use and small bone fractures using the GPRD database
Irvine D, Wise L.
Pharmacoepidemiology & Drug Safety:2008; 17 :S174
Association between Alendronate Usage and Vitreous detachment: A cohort study.
Shafe A CE, Wise L.
Pharmacoepidemiology & Drug Safety:2008; 17 :S165
The General Practice Research Database as a pregnancy registry system: Anticonvulsants as an example.
Charlton R, Weil J, Cunnington M, deVries C.
Pharmacoepidemiology & Drug Safety:2008; 17 :S159
Fracture risk in patients receiving concomitant bisphosphonate and proton pump inhibitors or bisphosphonates alone: The UK General Practice Research Database. deVries F, Cooper A, Logan R, Cockle S, Cooper C, VanStaa TP.
Pharmacoepidemiology & Drug Safety:2008; 17 :S151
Validation of pregnancy identification algorithm within the GPRD.
Devine ST, Hammad TA, Andrews EB.
Pharmacoepidemiology & Drug Safety:2008; 17 :S126
Diagnostic codes for sudden cardiac death and ventricular arrhythmia functioned poorly to identify outpatient events in the GPRD.
Hennessy S, Leonard CE, Palumbo CM, Bilker WB, Newcomb C, Kimmell S.
Pharmacoepidemiology & Drug Safety:2008; 17 :S86
The contribution of persistence and compliance with bisphosphonates on fracture outcomes.
Reitbrock S, Olson M, Vanstaa TP
Pharmacoepidemiology & Drug Safety:2008; 17 :S78
Chronic atrial fibrillation: Incidence, Prevalence and prediction of stroke using the CHADS2 risk stratification scheme.

19.
20.
21.
22.
23.
24.
Gallagher, AM, Reitbrock S, Heeley E, Plumb J, Vanstaa TP.
Pharmacoepidemiology & Drug Safety:2008; 17 :S31
Exploring channelling bias of anti-epileptic drugs in epilepsy patients in a US claims database and a UK
General Practice database.
Ishihara-Paul L, Webb DJ, Juneja M, Kanakarja P, Weil J.
Pharmacoepidemiology & Drug Safety:2008;17:S23
Initiation and persistence of warfarin or aspirin treatments in chronic atrial fibrillation: Do the appropriate patients receive stroke prophylaxis?
Gallagher AM, Reitbrock S, Plumb J, VanStaa TP.
Pharmacoepidemiology & Drug Safety:2008; 17 :S11
Does the varied use of NSAIDs explain the differences in the risk of myocardial infarction?
Vanstaa T, Reitbrock S, Setakis E.
Pharmacoepidemiology & Drug Safety:2008; 17 :S9
Regional variations in joint replacement: disease or service provision?
Culliford D, Maskell J, Mullee M, Arden N.
British Society of Rheumatology (2008)
Temporal changes in the trends of total and unicondylar knee replacements in the UK.
Maskell J, Culliford D, Mullee M, Arden K.
British Society of Rheumatology (2008)
Antibiotic prescribing for otitis media in children in UK primary care: have the national guidelines affected GP prescribing practice?
Thompson, P.L., Gilbert, R., Long, P.F., Saxena, S., Sharland, M and Wong, I.C.K.
Pharmacoepidemiology and Drug Safety. 2008;17:S273.
25.
26.
Do antibiotics for otitis media reduce the risk of mastoiditis in children?
Thompson, P.L., Gilbert, R., Long, P., Saxena, S., Sharland, M and Wong, I.C.K.
Archives of Disease in Childhood. 2008;93:A75.
Do antibiotics for otitis media reduce the risk of mastoiditis in children?
Thompson, P.L., Gilbert, R., Long, P., Saxena, S., Sharland, M and Wong, I.C.K.
International Journal of Pharmacy Practice. 2008;16:A10.
27.
Effect of antibiotics for otitis media on mastoiditis in children: A retrospective cohort study using the UK
General Practice Research database.
Thompson, P.L., Gilbert, R., Long, P., Saxena, S., Sharland, M and Wong, I.C.K. Pharmacoepidemiology and
Drug Safety. 2008;17:748.
28. Emission inventory development for the Hong Kong special administrative region.
Pollack A, Morris R, Yeung D, Sham P, Fung C, Leung K.
Proceedings of the Air and Waste Management Association's Annual Conference and Exhibition, AWMA 2008;
7: 4393-4396.
29. Supporting UK-wide e-clinical trials and studies.
Stell A, Sinnott R, Ajayi O.
ACM International Conference Proceeding Series, 2008; 320: art. no. 1341828.
30. Discrimination of civilian vehicles using wide-angle SAR.
Dungan KE, Potter LC, Blackaby J, Nehrbass J.
Proceedings of SPIE - The International Society for Optical Engineering, 2008; 6970: art. no. 69700Z.
31. Minimizing risk in the treatment of moderate-to-severe Crohn's disease.
Cohen, Russell D.; Mahadevan-Velayos, Uma; Panaccione, Remo.
Gastroenterology and Hepatology 4.11: 1-12. Gastro-Hep Communications, Inc. (Nov 2008)

1. The effect of heart rate and it’s changes on cardiovascular disease and mortality.
Setakis E, Williams TJ, van Staa TP
Pharmacoepidemiology & Drug Safety (2007)
2.
Onset and offset of fracture benefit associated with bisphosphonate use.
Gallagher AM, Rietbrock S, Olson M, Leufkens HGM, van Staa TP.
Pharmacoepidemiology & Drug Safety (2007)
3. The incidence of Wegener’s granulomatosis and Chrug Strauss syndrome in the UK General Practice
Database
Watts R, Al-Taiar A, Skinner J, Scott D, MacGregor A.
American College of Rheumatology (2007)
4.
5.
What are antibiotics being prescribed for in children, and how has this changed over time in UK general practice?
Thompson, P.L., Gilbert, R., Long, P., Sharland, M. and Wong, I.C.K.
International Journal of Pharmacy Practice. 2007;15:A24.
Changes in antibiotic-resistance rates for invasive Haemophilus Influenzae isolates in England and Wales and their association with antibiotic prescribing in the community.
Ladhani, S., Heath, P., Ramsay, M., Thompson, P., Sharland, M. and Slack, M.
Archives of Disease in Childhood. 2007; 92:A80.
What are antibiotics being prescribed for in children, and how has this changed over time in UK general
6. practice?
Thompson, P.L., Gilbert, R., Long, P., Sharland, M. and Wong, I.C.K.
Archives of Disease in Childhood. 2007;92:A86
7. Costs and effectiveness of travoprost versus a dorzolamide + timolol fixed combination in first-line treatment of glaucoma: Analysis conducted on the United Kingdom General Practitioner Research
Database.
Lafuma A, Berdeaux G.
Current Medical Research and Opinion , 2007; 23(12): 3009-3016.
8. The utility of the general practice research database to examine selected congenital heart defects - A validation study.
Wurst, Keele E.; Ephross, Sara A.; Loehr, James; et al.
Pharmacoepidemiology and Drug Safety . 2007;16:S131.
9. Validation of neural tube defects in the general practice research database.
Devine, Scott; West, Sue; Eaton, Susan; et al.
Pharmacoepidemiology and Drug Safety . 2007;16:S130-S131.
10. Validation of UK general practice research database mother-baby linkage using a sample of congenital heart defect records.
Wurst, Keele E.; Ephross, Sara A.
Pharmacoepidemiology and Drug Safety . 2007;16:S150.
1.
Blood pressure lowering thresholds and stroke
Qizilbash N, Mander A, Feudjo-Tepie M, Boudiaf N.
Pharmacoepidemiology & Drug Safety (2006); 15: S271
A time-trend analysis of all clinical activity, amoxicillin/co-amoxiclav prescribing, acute otitis media and

2. acute mastoiditis in paediatrics in general practice.
Thompson, P.L., Gilbert, R., Long, P., Murray. M.L., Sharland, M. and Wong, I.C.K.
Pharmacoepidemiology and Drug Safety . 2006;15:S147-S148
3. Prescription patterns of major antidepressant drugs in adults diagnosed with depression: A GPRD based study.
Bineau, Sebastien; Saragoussi, Delphine; Despiegel, Nicolas; et al.
Pharmacoepidemiology and Drug Safety . 2006;15:S163.
4. Risk adjusted sequential and longitudinal monitoring drug performance using GPRD.
Ma, Mark L.; Hornbuckle, Kenneth; Voss, Simon; et al.
Pharmacoepidemiology and Drug Safety . 2006;15:S33.
5. Verification of observational data using GPRD.
Williams, Tim J.; Murray-Thomas, Tarita; Ambersley, Brendon.
Pharmacoepidemiology and Drug Safety . 2006;15:S220.
6. Use of oral glucocorticoids and risk of suicide: A cohort study in the general practice research database.
Souverein, Patrick C.; Speksnijder, Niels; van Staa, Tjeerd P.; et al.
Pharmacoepidemiology and Drug Safety . 2006;15:S3.
1.
Use of the General Practice Research Database to detect drug-induced autoimmune disease.
Schoonen WM, Somers EC, Hall AJ
Pharmacoepidemiology & Drug Safety (2005); 14: S199
2.
3.
4.
5.
A reanalysis of two studies that reported contrasting results on the association between statin use and risk of fracture in the same database.
De Vries F, de Vries C, Cooper C, Leufkens H, van Staa TP
Pharmacoepidemiology & Drug Safety (2005); 14: S199
Use of antiepileptic drugs and risk of fractures: a case-control study among patients with epilepsy.
Souverein PC, Webb DJ, Weil J, van Staa TP, Egberts TCG
Pharmacoepidemiology & Drug Safety (2005); 14: S192-193
Rates of serious vascular events among patients dispensed type 2 antidiabetic medications in the U.S. and
U.K.
Velentgas P, Cole JA, Costa L, Ziyadeh N, Shea K, Seeger JD, Walker AM
Pharmacoepidemiology & Drug Safety (2005); 14: S173-174
The risk of venous thromoboembolism associated with cyproterone acetate amongst men with advanced carcinoma of the prostate.
Seaman H, Farmer RDT
Pharmacoepidemiology & Drug Safety (2005); 14: S172
6.
7.
8.
Matched retrospective cohort study of breast cancer incidence among initiators of racemic zopiclone, temazepam, and zolpidem in the General Practice Research Database.
Eng PM, Ziyadeh N, Nordstrom BL, Caron J, Amato D, Seeger JD
Pharmacoepidemiology & Drug Safety (2005); 14: S162
Changes in the prevalence and incidence of coronary heart disease in the UK between 1992 and 2001.
Seaman H, Hutchinson A, Farmer RDT, de Vries CS
Pharmacoepidemiology & Drug Safety (2005); 14: S155-156
Characteristics of end stage renal disease patients receiving phosphate binder therapy in UK primary care.
Gallagher AM, Elgazzar H, Hughes G
Pharmacoepidemiology & Drug Safety (2005); 14: S145-146

9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
A novel methodology for measuring the influence of comorbidity in disease outcome studies.
Kiri VA, Visik G, Muellerova H, MacKenzie G
Pharmacoepidemiology & Drug Safety (2005); 14: S135-136
Risk of fracture in patients using high-dose intermittent oral glucocorticoids.
De Vries F, van Staa TP, Bracke M, Cooper C, Lammers JW, Leufkens H
Pharmacoepidemiology & Drug Safety (2005); 14: S133-134
The association between antiepileptic drug use and aplastic anaemia.
Van den Bemt PMLA, Souverein PC, van Staa TP, Meyboom RHB, van Solinge WW, Egberts TCG, Leufkens
BGM
Pharmacoepidemiology & Drug Safety (2005); 14: S109
Tranexamic acid, menorrhagia, and venous thromoboembolism: a case-control study using the GPRD.
Sundstrom A, Seaman H, Alfredsson L
Pharmacoepidemiology & Drug Safety (2005); 14: S108
Risk factors for inflammatory bowel disease in the general population.
Garcia Rodriguez LA, Gonzalez-Perez A, Johansson S, Wallander MA
Pharmacoepidemiology & Drug Safety (2005); 14: S99-100
Evaluation of prescribing to patients with coronary heart disease against the national service framework.
Hutchinson A, Seaman H, Farmer R, de Vries C
Pharmacoepidemiology & Drug Safety (2005); 14: S85-86
Pneumonia in an asthma cohort in general practice in the UK.
Garcia Rodriguez LA, Wallander MA, Johansson S, Ruigomez A
Pharmacoepidemiology & Drug Safety (2005); 14: S97-98
Demyelinating disorders are more common among patients with inflammatory bowel disease (IBD) even in the absence of anti-TNFα therapy.
Gupta G, Gelfand JM, Lewis JD
Pharmacoepidemiology & Drug Safety (2005); 14: S66
Propensity score matching to identify cohorts of patients prescribed type 2 diabetes medications in the
General Practioner Research Database.
Cole JA, Velentgas P, Ziyadeh N, Costa L, Shea K, Seeger J, Walker AM
Pharmacoepidemiology & Drug Safety (2005); 14: S62
Non-steroidal anti-inflammatory drugs and risk of first hospital admission for heart failure in the general population.
Huerta C, Varas Lorenzo C, Castellsague J, Garcia Rodriguez LA
Pharmacoepidemiology & Drug Safety (2005); 14: S59
Depression and the underlying hazard of suicidal behavior.
Rietbrock S, Martinez C
Pharmacoepidemiology & Drug Safety (2005); 14: S55
Trends in prescribing of methylphenidate in the UK.
Williams TJ, Hughes G, Martinez C
Pharmacoepidemiology & Drug Safety (2005); 14: S54-55
Duration of therapy among patients dispensed type 2 diabetes medications in the U.S. and U.K.
Velentgas P, Cole JA, Ziyadeh N, Costa L, Shea K, Seeger JD, Walker AM
Pharmacoepidemiology & Drug Safety (2005); 14: S49
Lymphoma risk in patients with rheumatoid arthritis who received 2 or more disease modifying

22.
23.
24.
25.
26.
27.
1.
2.
3.
4.
5.
6.
7. antirheumatic drugs (DMARDs): a retrospective cohort study in the GPRD.
Mines DI, Novelli LA, Yu H
Pharmacoepidemiology & Drug Safety (2005); 14: S30
New users of inhaled corticosteroids (ICS) in the United Kingdom have higher probability of continuous use than new users in the Netherlands.
Menckeberg TT, Pokladnikova J, Bouvy ML, Belitser SV, Bracke M, Raaijmakers JAM, Leufkens HGM
Pharmacoepidemiology & Drug Safety (2005); 14: S29
Epidemiology and treatment patterns of psoriasis in the General Practice Research Database (GPRD).
Gelfand JM, Wang X, Liu Q, Neiman A, Weinstein R, Margolis DJ, Troxel AB
Pharmacoepidemiology & Drug Safety (2005); 14: S23-24
Incidence of selected outcomes among matched cohorts of initiators of racemic zopiclone, temazepam, and zolpidem in the General Practice Research Database.
Eng PM, Ziyadeh N, Nordstrom BL, Caron J, Amato D, Seeger JD
Pharmacoepidemiology & Drug Safety (2005); 14: S22-23
Use of beta-blockers and risk of hip and vertebral fracture: relationships to daily and cumulative dose.
De Vries F, Souverein PC, De Bruin ML, Leufkens HGM, Cooper C, Van Staa TP
Pharmacoepidemiology & Drug Safety (2005); 14: S21-22
Prevalence of osteoarthritis and rheumatoid arthritis: cross-sectional analysis in a follow-up study.
Gonzalez-Perez A, Garcia Rodriguez LA, Johansson s, Wallander MA
Pharmacoepidemiology & Drug Safety (2005); 14: S7-8
The risk of first seizure associated with mefenamic acid in women of reproductive age
Mines DI, Novelli LA
Pharmacoepidemiology & Drug Safety (2004) 13: S333-4
Natural history of dyspepsia in general practice: incidence, comorbidity and risk factors
Ruigomez A, Wallander MA, Johannson, Garcia Rodriquez LA
Pharmacoepidemiology & Drug Safety (2004) 13: S309
Natural history of chest pain in general practice setting
Ruigomez A, Johansson S, Wallander MA, Garcia Rodriguez LA
Pharmacoepidemiology & Drug Safety (2004) 13: S308-9
Estimating annual prevalence of clinically-significant psoriasis in the General Practice Research Database
(GPRD)
Crane MM, Hastie JM, Black CL
Pharmacoepidemiology & Drug Safety (2004) 13: S306-7
A retrospective cohort study of diabetes mellitus and antipsychotic treatment in the UK
Cavazzoni P, Hornbuckle K, Carlson C, DeLisle F, Noel R, Breier A
Pharmacoepidemiology & Drug Safety (2004) 13: S304
Increased rates of diagnosis for hypertension or dyslipidaemia in patients previously identified with one of these risk factors: data from the United Kingdom
MacDonald TM, Morant SV, Mozaffari E
Pharmacoepidemiology & Drug Safety (2004) 13: S302-3
The risk of venous thromboembolism associated with cyproterone acetate in combination with ethinyloestradiol - an update
Seaman HE, de Vries CS, Farmer RDT
Pharmacoepidemiology & Drug Safety (2004) 13: S275

8.
Cross-over cohort study of incident VTE in women exposed to cyproterone in UK primary care
Moseley JNS
Pharmacoepidemiology & Drug Safety (2004) 13: S274-5
9. Treatment patterns for hypertension, dyslipidaemia, and both conditions in the United Kingdom: 1997-
2001
MacDonald TM, Morant SV, Baker CL, Mozaffari E
Pharmacoepidemiology & Drug Safety (2004) 13: S237-8
10.
11.
Systemic lupus erythematosus: calculating the prevalence of relapsing-remitting disease using left-censored data
Nightingale AL, de Vries CS, Farmer RDT
Pharmacoepidemiology & Drug Safety (2004) 13: S230
Measuring incidence rates using GPRD: how soon after registration do incidence rates reach baseline levels?
Lewis JD, Bilker WB, Weinstein R, Strom BL
Pharmacoepidemiology & Drug Safety (2004) 13: S230-1
12.
13.
14.
15.
16.
17.
18.
19.
Methodological issues in determining daily hormonal contraceptive exposure on the General Practice
Research Database
Snowball JM, Farmer RDT
Pharmacoepidemiology & Drug Safety (2004) 13: S157-8
Medications prescribed before and during early pregnancy in a cohort of 81 975 mother-baby pairs: a population based study using the automated data of the General Practice Research Database
Hardy JR, Leaderer BP, Holford TR, Hall GC, Bracken MB
Pharmacoepidemiology & Drug Safety (2004) 13: S138-9
First use of oral contraceptives before and after the pill scare in the UK
Farmer RD, de Vries CS, Seaman HE
Pharmacoepidemiology & Drug Safety (2004) 13: S138
Drug interactions and risk of acute bleeding leading to hospitalisation or death in patients with chronic atrial fibrillation (AF) treated with warfarin
Gasse C, Hollowell J, Meier CR, Troost J, Schneider V, Haefeli WE
Pharmacoepidemiology & Drug Safety (2004) 13: S134-5
Survival analysis to examine the risk of a recurrent stroke of patients in the General Practice Research
Database
Short D, Chapman S
Pharmacoepidemiology & Drug Safety (2004) 13: S134
The increasing proportion of patients with type 2 diabetes converting to insulin therapy in the UK
Mulnier H, Lovell D, Lawrenson R
Pharmacoepidemiology & Drug Safety (2004) 13: S129
Predicting cardiac arrhythmias and sudden death among diabetic users of arrhythmogenic nonantiarrhythmic drugs
De Bruin ML, van Staa TP, Belitser SV, Leufkens HGM, Hoes AW
Pharmacoepidemiology & Drug Safety (2004) 13: S124
In-utero exposure to antihistamines and the risk of congenital hypospadias or cryptorchidism in male births
Williams T, Hughes G, Martinez C
Pharmacoepidemiology & Drug Safety (2004) 13: S126

20.
Adverse drug reaction profiles for fluoxetine, paroextine and amitriptyline using data recorded by general practitioners in the United Kingdom (UK)
Davis S, Rietbrock S, Martinez C
Pharmacoepidemiology & Drug Safety (2004) 13: S118-9
21.
Treatment of high-risk hypertensive patients in the United Kingdom: 1997-2001
MacDonald TM, Morant SV, Baker CL, Mozaffari E
Pharmacoepidemiology & Drug Safety (2004) 13: S103
22. Sudden unexpected death (SUDEP) in children and adolescents with epilepsy
Hsia Y, de Vries CS
Pharmacoepidemiology & Drug Safety (2004) 13: S83
23.
24.
The risk of upper gastrointestinal tract bleeding associeated with mefenamic acid in women of reproductive age
Mines DI, Novelli LA
Pharmacoepidemiology & Drug Safety (2004) 13: S54-55
The incidence of ventricular fibrillation and ventricular tachycardia in a primary care population
Hughes G, Rietbrock S, Reiter C, Martinez C
Pharmacoepidemiology & Drug Safety (2004) 13: S48
25.
26.
A systematic approach for describing comorbidities using the UK General Practice Research Database
Roskell NS, Logie JW, Stender M, Feudjo-Tepie M
Pharmacoepidemiology & Drug Safety (2004) 13: S42
An algorithm to extract medical codes for diagnoses from unstructured free text recorded by general practitioners in the UK
Shah AD, Martinez C
Pharmacoepidemiology & Drug Safety (2004) 13: S41-2
27.
28.
Validity of the General Practice Research Database: a systematic review
Schoonen WM, Hall AJ
Pharmacoepidemiology & Drug Safety (2004) 13: S41
Low treatment rates and poor goal attainment in patients with concomitant hypertension and dsylipidaemia: data from the United Kingdom
MacDonald TM, Morant SV, Baker CL, Mozaffari E
Pharmacoepidemiology & Drug Safety (2004) 13: S29-30
29. Acute and long-term risk of femur fractures in patients on antipsychotics
30.
31.
32.
Hugenholz GWK, Heerdink ER, Nolen WA, Egberts TCG
Pharmacoepidemiology & Drug Safety (2004) 13: S21-2
Is there cross-reactivity between penicillins and cephalosporins? Investigaion of a large electronic medical record database.
Apter AJ, Kinman JL, Milker WB, Herlin M, Margolis DJ, Lautenbach E, Hennessy S, Strom BL
Pharmacoepidemiology & Drug Safety (2004) 13: S18
The effect of selective serotonin reuptake inhibitors on the risk of myocardial infarction in a cohort of patients with depression
Kimmel SE, Berlin JA, Oslin DW, Weinstein RB, Kinman JL, Sauer WH, Lewis JD
Pharmacoepidemiology & Drug Safety (2004) 13: S6
Use of oral steroids and the risk of acute myocardial infarction in the U.K.
Varas-Lorenzo C, Garcia-Rodriguez LA, Maguire A, Perez-Gutthann S

Pharmacoepidemiology & Drug Safety (2004) 13: S5-6
33.
A comparison of the cause of death recorded in the General Practice Research Database with national mortality statistics in England and Wales
Shah AD, Martinez C
Pharmacoepidemiology & Drug Safety (2004) 13: S2-3
34. A prospective study of alcoholism and the risk of Parkinson's disease.
Hernán, Miguel A.; Logroscino, Giancarlo; García Rodríguez, Luis A.
Journal of Neurology 251.SUPPL. 7: VII/14-VII/17.
1.
2.
3.
The 'Drug Allergy and Intolerance' Structured Data Area: an additional information source of suspected
Adverse Drug Reactions (ADRs) in the Full Feature General Practice Research Database
Martinez C, Davis S, Heeley E, Moseley J, Rietbrock S.
Pharmacoepidemiol and Drug Safety (2003); 12: S244
Auditing the quality of data in the General Practice Research Database
Davis S, Rietbrock S, Rubino A, Shah AD, Williams T, Martinez C.
Pharmacoepidemiol and Drug Safety (2003); 12: S61
An algorithm to derive a numerical daily dose from text dosage instructions in the General Practice
Research Database
Shah AD, Martinez C.
Pharmacoepidemiol and Drug Safety (2003); 12: S60-61
4. Impact of Therapy Used in Clinical Practice on Lower Urinary Tract Symptoms/Benign Prostatic
Hyperplasia (LUTS/BPH) Disease Progression.
Berges R.
European Urology, 2003; Supplement 2(7): 19-24.
1. Linkage of Socio-Economic Status data to the General Practice Research Database
Williams TJ, Martinez C
Pharmacoepidemiology & Drug Safety (2002) 11: S168
2.
Validation of birth recording and development of a mother-baby link in the FF-GPRD
Rubino A
Pharmacoepidemiology & Drug Safety (2002) 11: S70-71
3. Cardiovascular outcomes in hypertensives treated with ACE inhibitors or calcium channel blockers differ:
Evidence from UK General Practice Research Database.
McInnes, Gordon T.; Hole, David J.; Murray, Lilian S.; et al.
Circulation . 2002;106(19 Supplement):574-575.
1. How do symptoms indicative of BPH progress in real life practice? The UK experience.
Clifford GM, Logie J, Farmer RDT.
European Urology, 2000; 38(SUPPL. 1): 48-53.
2. What is the impact of differential follow-up time on studies of disease burden in the General Practice
Research Database?
Eaton S, McQuay L, Clark D.
Pharmacoepidemiol Drug Safety . 2000;9(Supplement 1):S144-S145.

3. Upper gastrointestinal complications associated with use of non-steroidal anti-inflammatory drugs according to the nature of the outcome.
Hernandez-Diaz, Sonia; Garcia-Rodriguez, Luis A.
Pharmacoepidemiology and Drug Safety . 2000;9(Supplement 1):S67.
4. Trends in ACE inhibitor prescribing in general practice (1993-1997): An investigation using the General
Practice Research Database.
Heatlie, Heath F.; Norwood, Jeff; Bashford, James.
Pharmacoepidemiology and Drug Safety . 2000:9(Supplement 1):S7.
5. The treatment of Bell's palsy in general practice.
Rowlands, Sam; Hughes, Richard A. C.; Burney, Peter; et al.
Pharmacoepidemiology and Drug Safety . 2000;9(Supplement 1):S33.
6. The risk of liver injury associated with minocycline.
Seaman, Helen E.; Lawrenson, Ross A.; Williams, Tim J.; et al.
Pharmacoepidemiology and Drug Safety . 2000:9(Supplement 1):S47.
7. Selective serotonin reuptake inhibitors (SSRIs) and acute myocardial infarction (AMI).
Meier, Christoph R.; Schlienger, Raymond G.; Jick, Hershel.
Pharmacoepidemiology and Drug Safety . 2000;9(Supplement 1):S10.
8. Prevalence of asthma by severity in the general population.
Heatlie, Heath F.; Frischer, Martin; Clark, Wendy.
Pharmacoepidemiology and Drug Safety . 2000;9(Supplement 1):S26-S27.
9. Prevalence and incidence of diagnosed allergic rhinitis in the UK general and asthmatic populations.
Castellsague, Jordi; Garcia Rodriguez, Luis Alberto.
Pharmacoepidemiology and Drug Safety . 2000;9(Supplement 1):S82-S83.
10. Patterns of prescribing of hormonal emergency contraception by general practitioners in England and
Wales.
Ineichen, Berhard; Logie, John W.; Rowlands, Sam; et al.
Pharmacoepidemiology and Drug Safety . 2000;9(Supplement 1):S56-S57.
11. Patterns of Hormone Replacement Therapy in the UK.
Causier, Susan E.; de Vries, Corinne S.; Williams, Tim J.; et al.
Pharmacoepidemiology and Drug Safety . 2000;9(Supplement 1):S130.
12. Initial therapy of inflammatory bowel disease (IBD) in the United Kingdom.
Lewis, James D.; Bilker, Warren B.; Brensinger, Colleen; et al.
Pharmacoepidemiology and Drug Safety . 2000;9(Supplement 1):S17-S18.
13. Incidence of ocular melanoma in the general population and glaucoma patients.
Huerta, Consuelo; Garcia Rodriguez, Luis Alberto.
Pharmacoepidemiology and Drug Safety . 2000;9(Supplement 1):S8.
14. Incidence of newly diagnosed heart failure in general practice.
Johannson, Saga; Wallander, Mari-Ann; Ruigomez, Ana; et al.
Pharmacoepidemiology and Drug Safety . 2000;9(Supplement 1):S13.
15. A study of antibiotic resistance in women treated for urinary tract infections.
Logie, John W.; Lawrenson, Ross A.
Pharmacoepidemiology and Drug Safety . 2000;9(Supplement 1):S56.
16. Antidepressant exposure and the risk of hip fractures: A case-control study using the UK general practice research database (GPRD).
Hubbard, Richard; Smeeth, Liam; Smith, Chris; et al.
Pharmacoepidemiology and Drug Safety . 2000;9(Supplement 1):S38.
17. Venous thromboembolism and combined oral contraceptives: Does the type of progestogen make a difference?
Lawrenson R, Farmer R.
Contraception, 2000; 62(2 SUPPL. 1): S21-S28.
1. BAPEN symposium on 'artificial nutrition support: No longer an expensive luxury!!' - Outcomes of undernutrition in patients in the community with cancer or cardiovascular disease
Edington, J.; Winter, P.D.; Coles, S.J.; Gale, C.R.; Martyn, C.N.
Proceedings of the Nutrition Society 58.3: 655-661. CAB International. (1999)

1. The epidemiology and medical care usage of patients with hepatitis B in a British population: The General
Practice Research Database.
Rosenberg DM, Cook SF, Eaton, S.
Hepatology . 1998;28(4):232A.
2. Ocular events among users of inhaled and oral corticosteroids.
Jick SS, Maier WC.
Eur Respir J . 1998;12(Supplement 29):82s.
1. Increased medical utilization among a random sample of irritable bowel syndrome (IBS) sufferers compared to matched controls using 1995 data from the general practice research database (GPRD).
Saunders W, Vasilakis C.
Am J Epidemiol . 1997;145(11 SUPPL):S9.
1.
Exploring practical approaches to maximising data quality in electronic healthcare records in the primary care setting and associated benefits. Report of panel-led discussion held at SAPC in July
2014.
Dungey S, Glew S, Heyes B, Macleod J, Tate AR.
Primary health care research & development 2016 Jan 18:1-5.
2. Recent advances in the utility and use of the General Practice Research Database as an example of a UK
Primary Care Data resource.
Williams T, van Staa T, Puri S, Eaton S.
Therapeutic Advances In Drug Safety, April 2012; vol. 3, 2: pp. 89-99
3.
GPRD in the UK
Wood L
In: Pharmacovigilance (2002), pp 373-378; Mann RD , Andrew EB (editors)
The UK General Practice Research Database, A powerful e-Clinical Research Tool
Clinical Research Focus (2002), 13, 48-50 4.
5. UK GPRD now available online
Scrip (2001); 2634: 5
6. The UK General Practice Research Database
Garcia Rodriguez LA, Perez-Gutthann S, Jick SS
In: Pharmacoepidemiology, third edition (2000), pp 375-385; BL Storm (editor)
7. Cost effectiveness of migraine therapy: evaluating new acute treatments using the example of the triptans
Millson,DS Clark,W Ward,H & Frischer,M
In: Key Advances in the Effective Management of Headache (Goadsby,P Dowson,A & Miles,A editors).
BMA/Aesculapius Medical Press. London 1999
8. Clinical information for research; the use of general practice database
Lawrenson R, Williams T, Farmer R
J Pub Health Med (1999); 21(3): 299-304
9. Sviluppo e uso dei database in medicina generale in Europa (Development of database in European general practice)
Lauri D
Ricerca e Pratica (1999); 15, 9-19

10.
Using the General Practice Research Database
Hynes D
Update (1999); 888-890
Updating the database
Lever F
Pharmaceutical J (1999); 262: 880
11. Realising the value of the medical record
Law J
Scrip (1999); 23-25
12.
UK MCA to enhance GPRD database
Scrip (3 November 1999); 2486
13.
£3m boost for GP database
Pulse (1 May 1999)
14.
15.
The Department of Medicines Management at Keele University
Pharmaceutical J (January 1999); 262
Medicines Control Agency takes over GP research database
Yamey G
Br Med J 1999); 319: 1153
16.
A Bug in the heart
Hawkes N
The Times (February 1999)
17.
UK primary care databases lead the way
Fletcher P
Adverse Drug React Toxicol Rev (1999); 18(2): 57-60
18. Key Health Statistics from General Practice 1996
National Statistics(1998) Series MB6 No 2
19. Issues and directions in prescribing analysis
Frischer M, Chapman S
In: Panton R (ed) Medicines Management BMA publications (1998)
20. The General Practice Research Database
Lawson DH, Sherman V, Hollowell J
Q J Med (1998); 91: 445-452
21. Principles of epidemiologic research on adverse and beneficial drug effects
Jick H, Garcia Rodriguez LA, Perez Gutthann S
Lancet (1998); 352: 1767-1770
22.
GP’s digital database tracks patient trends
Banks I
Doctor (20 March 1997)
23. Key Health Statistics from General Practice 1996
National Statistics(1996) Series MB6 no 1
24. The General Practice Database
In: Measuring Morbidity and Health: What information can General Practice deliver? Eames M (ed),
Hatfield:University of Hertfordshire (1996)

25.
26.
Fact File on Schizophrenia
Pharmaceutical Times (December 1996)
Fact File on Osteoporosis
Pharmaceutical Times (November 1996)
27.
Medical know how
Law Society Gazette (September 1996)
28. A major resource for drug safety studies. The General Practice Research Database (formerly VAMP
Research)
Jick H
Carshalton: Centre for Medicines Research (1995)
29. Managing adverse reaction information
Mann RD
Drug Information J (1992); 26: 583-587
30. Pharmacoepidemiology using a UK database of primary care records
Hall G
Pharmacoepidemiology and Drug Safety (1992); 1: 33-37
31. 10 Years experience with integrated general practice
Dean AD, Boda I
Microcomputers in Medicine (1987); 15: 342-375
32.
33.
A computer in the dispensary
MIMS (1986)
The computer key to information in general practice
Kayll J
Current Perspectives in Health Computing (conference proceedings) (1986)
34.
Trends in general practice computing
Dean AD
Royal College of General Practice Dispensing Systems (1985); 5: 3335
35. The IGP system from VAMP
Practice Computing (1984); 3(4)
SELECTED EDITORIALS/LETTERS
1 The CPRD and the RCGP: building on research success by enhancing benefits for patients and practices
Kousoulis A, Rafi I, de Lusignan S.
Br J Gen Pract Feb 2015, 65 (631) 54-55; DOI: 10.3399/bjgp15X683353
2 Limitations of prior event rate ratio adjustment
Gallagher A.
BMJ 2009
In response to: BMJ. 2009 Jan 27;338:b81.
PMID: 19174434

3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
Low-level prescribing not necessarily good prescribing
Teeling-Smith G
Prescriber (July 1990); 37-42
Addressing drug discontinuation using the VAMP research data bank
Lis Y, Chukwujindu J, Cockburn I
Therapie (1993); 48: 427
Is co-trimoxazole safe? (letter)
Jick H, Derby LE
Lancet (1995); 345: 1118-1119
Haemophilus influenza vaccine (letter)
Jick H, Withers JM, Dean AD
Br J Gen Pract (1995); 45(391): 107
Risk of acute myocardial infarction and low-dose combined oral contraceptives (letter)
Jick H, Jick SS, Myers MW, Vasilakis C
Lancet (1996); 347: 627-628
A Database worth saving (commentary)
Jick H
Lancet (1997); 350: 1045-1046
General practice research database provides detailed anonymised data.
Lockwood MJ.
BMJ. 1996;313(7059):757.
The UK general practice research database
Walley T, Mantgani A
Lancet (1997); 350: 1097-1099
Use of the UK General Practice Research Database for pharmacoepidemiology
Garcia Rodriguez LA, Perez Gutthann S
Br J Clin Pharmacol (1998); 45: 419-425
General Practice Research Database for prescribing analysis (letter)
Frischer M, Chapman S, Bashford J, Norwood J, Heatlie H
Lancet (1998); 351: 453-454
Conceptions and terminations after the 1995 warning about oral contraceptives (letter)
Furedi A, Paintin D
Lancet (1998); 352: 323-324
Seasonal variations in the incidence of acute myocardial infarction (letter)
Meier CR
J Am Coll Cardiol (1998); 32: 2103-2104
Oral contraception and health
Vessey MP
Br J Gen Pract (October 1998); 1639-1640
Pharmacovigilance into 2000
McNamee D
Lancet (1999); 354: 1406
Prescription of proton pump inhibitors: indications may be more specific than suggested by GP records
(letter)
Mant J, Murphy MFG, Vessey MP
Br Med J (1999); 318: 534

18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30
31
Antidepressants and upper gastrointestinal bleeding
Li Wan Po A
Br Med J (1999); 319: 1081-1082
DoH seems to have underestimated incidence of venous thromboembolism in users of combined oral contraceptives (letter)
Lawrenson RA, Whalley A, Simpson E, Farmer RDT
Br Med J (1999); 319: 387
Drug treatments that reduce fracture rate are underused after vertebral fractures (letter)
Torgerson DJ, Dolan P
Br Med J (1999); 318: 1698
Third generation oral contraceptives: Caution is still justified (editorial)
Skegg DCG
Br Med J (2000); 321: 190-191
Pitfalls of pharmacoepidemiology (editorial)
Skegg DCG
Br Med J (2000); 321: 1171-1172
Association between SSRIs and upper gastrointestinal bleeding (letter)
Br Med J (2000); 320: 1405-1406
Netting an important database (editorial)
Lancet (2001); 357: 649
How to set priorities in heart care (forum)
Ashcroft D
Pharmaceutical Journal (2001); 266:334-335
Revitalizing the General Practice Research Database: plans, challenges, and opportunities
Wood L, Coulson R
Pharmacoepidemiol Drug Saf (2001); 10:379-383
The general practice research database: role in pharmacovigilance.
Wood L, Martinez C.
Drug Saf. (2004); 27(12): 871-81.
The potential of UK clinical databases in enhancing paediatric medication research.
Wong IC, Murray ML.
Br J Clin Pharmacol. (2005) Jun;59(6):750-5.
Up-to-date findings show change in acute otitis media consultation trend [Letter].
Thompson, P.L., Murray, M.L., Sharland, M. and Wong, I.C.K.
British Journal of General Practice. 2006;56:379-380
Pragmatic randomised trials using routine electronic health records: putting them to the test. van Staa TP, Goldacre B, Gulliford M, Cassell J, Pirmohamed M, Taweel A, Delaney B, Smeeth L.
BMJ . 2012;344:e55
Unlocking the research potential of the GP electronic care record.
Wallace P, Delaney B, Sullivan F.
Br J Gen Pract. 2013 Jun;63(611):284-5.
PMID: 23735377