5 As of Obesity Management Shahebina Walji, MD, CCFP Clinical L ecturer, University o f Calgary Medical Director, Calgary Weight Management Centre www.cwmc.ca s.walji@cwmc.ca Objectives • Review Key Principles of Obesity Management • Become Familiar with the 5As of Obesity Management™ • Better understand the etiological factors contributing to obesity • Increase ability to create a patient focused care plan to help with weight management How does obesity affect your patient’s life? Leger Survey, 2011 Patient experience: • 50% state that weight has had a negative impact on relationships with friends, family and/or spouses. • 55% have low self-­esteem • 33% withdraw from social situations • 75% have tried to lose weight for over 11 years. • 25% have tried countless times to lose weight • Less than 20% receive help their from physician. Why? • Information seldom helpful • Physicians lack sensitivity • Patients want more support in self-­management, tailored strategies and reliable resources Leger Survey, 2011 As a physician, what is your role in obesity management? What makes managing obesity so challenging for physicians? Weight Management Today: What we’ve been doing wrong… • Obesity has been viewed by many clinicians as a homogeneous condition amenable to simply “eating less and moving more”. • We have not consistently been distinguishing between different causes or stages of obesity. • Reality: People seeking weight-­loss support often present with a range of barriers, including mental health issues, chronic pain and family or social issues. Key Principles of Obesity Management Photo c ourtesy of t he Canadian Obesity Network Key Principles of Obesity Management • Obesity is a Chronic (Progressive) Medical Condition • Obesity management is about improving health and well-being, not simply about reducing numbers on the scale • Early intervention is about addressing root causes and removing roadblocks • Success looks different for everyone • A patient’s “best” weight may never be an “ideal” weight. Case: John 54 year old business man, married with 2 children Vitals: BMI (today): 38 BMI (2012): 36 BP: 134/80 PMHx: Impaired Glucose Tolerance, Hypertension FHx: hypertension (both parents), T2 DM (sister) Case: John HPI Onset of weight gain in 40’s, corresponding to move to Calgary for work Current job involves ++ travel, lunch, and sometimes dinner meetings Previously active in recreational hockey;; since move and new job, has no time Progressive weight increase in last 12 years or so No previous attempts at weight loss PMx Impaired glucose tolerance 1 yr ago Hypertension x 5 yr Medications Atenolol FHx Obesity: mother, father, sister Hypertension – mother + father Diabetes -­ sister ROS/Lifestyle Assessment Skips breakfast most days Lunch and some dinners out No time for exercise (previously active in sports) Alcohol: 1-­2 servings per night on weekdays;; 6 per night on weekends How would you start a conversation with John about his weight? Possible Questions…. Are you concerned about the impact that your weight might be having on your health? Does your weight cause you any medical or personal difficulties? What types of changes to see you happening in your life if you do lose weight? Can we talk about your weight today? John: “I honestly don’t have time to worry about my weight right now.” “I am nowhere as heavy as my father was. I haven’t really thought about my weight as being all that related to my health. Do you have any concerns, doc?” “Yes, I am so frustrated! I want to lose weight, it feels like an impossible task. I am ready to do anything!!What do you suggest?” Medical Perspective How worried am I about the patient’s health across 3 dimensions? • Metabolic • Mechanical • Emotional Is there anything we need to prioritize before even thinking about weight reduction? What are the factors that are making weight management difficult and how can we reduce these barriers? 1. Obesity Class and Waist Circumference 2. Obesity Stage • Associated Health Conditions 3. Barriers to Weight Management 4. Readiness Obesity Class: BMI Classification WHO Classification: • • • Based on a patient’s BMI Gives us information about the SIZE of the patient. Does not provide information about the patient’s current health status Underweight <18.5 Normal Range 18.5-­‐24.9 Overweight 25.0-­‐29.9 Obesity • Class 1 30.0-­‐34.9 • Class 2 35.0-­‐39.9 • Class 3 40.0 + Waist Circumference: • Gives us more information about visceral adiposity, which may be a better marker of health/disease Waist Circumference Threshold European ♂ > 94 cm ♀> 80 cm Asian & Hispanic ♂ > 90 cm ♀> 80 cm Obesity Stage: EOSS: Edmonton Obesity Staging System INCREASED HEALTH RISK…INCREASED INTENSITY OF INTERVENTION Sharma et al. A Proposed Clinical Staging System for Obesity. International Journal of Obesity (2009) 1-­7 Edmonton Obesity Staging System. http://www.albertahealthservices.ca/ps-­ww-­eoss-­tool.pdf Obesity Stage: JOHN MHx: • IGT • HTN EOSS: Edmonton Obesity Staging System INCREASED HEALTH RISK…INCREASED INTENSITY OF INTERVENTION Sharma et al. A Proposed Clinical Staging System for Obesity. International Journal of Obesity (2009) 1-­7 Edmonton Obesity Staging System. http://www.albertahealthservices.ca/ps-­ww-­eoss-­tool.pdf Barriers to Weight Management Readiness 10-­‐POINT SCALE QUESTIONS: On a scale of 1-­‐10… • How important is it to you to manage your weight at this time? 9/10 • How ready are your to manage your weight at this time? 7/10 • How confident are you that you can manage your weight without support? 2/10 • How confident are you that you can manage your weight with support? 8/10 Summary: John Obesity Class: Class 2 Obesity Stage: Stage 2 Barriers: • Genetics • Medication/Alcohol • Social • Knowledge Readiness: Ready and Confident with Support Obesity is a chronic & often complex condition Obesity is a CHRONIC Medical Condition % Weight loss 20 – 30 % liraglutide ? 8-­‐10 % orlistat 3-­‐8 % Psychological MEDICATIONS: Approved in Canada: • Orlistat • Liraglutide Not approved for weight loss in Canada: • Locaserin • Phentermine-­Topiramate • Naltrexone-­Bupropion Orlistat: Mechanism of Action Intestinal lumen Gl Lipase + Orlistat Micelle Lymphatics Fatty Acids Monoglycerides Bile acids 30% of dietary fat is not absorbed Mucosal cell ADVISE: Liraglutide Mechanism of Action Energy Balance 3rd ventricle Liraglutide POMC NPY/ AGRP Hypothalamus Hypothalamus Increase Satiety Decrease Hunger POMC, proopiomelanocortin;; NPY, neuropeptide Y;; AGRP, agouti-­related peptide Secher A et al., J. Clin. Invest. 2014;; 24(10): doi:10.1172/JCI75276. Bariatric Surgery: 1. MOST EFFECTIVE TREATMENT FOR OBESITY 2. ACHIEVES GREATEST AMOUNT OF SUSTAINABLE WEIGHT LOSS 3. CAN BE RESTRICTIVE OR MALABSORPTIVE OR BOTH Laparoscopic Adjustable Gastric Banding Vertical Sleeve Gastrectomy Gastric Bypass How much will Patients Risk for Surgery? • Boston: Wee et al, JAMA Surgery • 600 individuals seeking bariatric surgery • 85% will accept 7% mortality risk with surgery • 1/10 will accept 10% mortality risk • Patient Expectations: 40% initial weight loss **Efficacy of Surgery** • 20-­30% loss of initial weight • Up to 30% patients will experience substantial weight regain. • 25% state they would be disappointed if they did not lose at least 25% initial weight JOHN • Obesity as a chronic condition • Health Risks associated with weight: HTN, IGT • Benefits of modest weight loss • Etiologies +/-­ Barriers ALL TREATMENT OPTIONS NUTRIONAL TIPS For Goal Setting 1. Keep a detailed food journal 2. Eat a big balanced breakfast within 1 hour of waking 3. Try to consume 3 balanced main meals separated by balanced snacks 4. Eat as close to the farm as possible 5. Be mindful of calories from beverages;; set specific limits 6. Portion control: portion plate, smaller plate, veggies first 7. Have a strategy for cravings JOHN Assessment Summary Obesity Class: Class 2 Obesity Stage: Stage 2 Agreed Upon Plan • No interest in surgery or obesity medications • Revisit BP medications Barriers: • Genetics • Medication • Social • Knowledge • Alcohol: Alternate water with alcohol on • Put on pedometer and track steps daily Readiness: • Ready & Confident with Support • Consider education re: glycemic control • Follow up!! weekends to halve his intake • Eat something in AM – anything – within 1 hour of waking