Insurability after Severe Traumatic Brain Injury The tragic skiing accident of Formula 1 racing champion Michael Schumacher increased the awareness of severe traumatic brain injury, which is a leading cause of death and disability worldwide. Traumatic Brain Injury (TBI) is defined as an injury resulting from a significant trauma to the brain. The most common causes are motor vehicle accidents, followed by falls (especially in older adults), sports accidents and assault. TBI has also become a relatively common injury among the combat military personnel deployed in areas where improvised explosive devices (IEDs) are employed as weapons. TBI can be distinguished from non-traumatic brain injuries, such as stroke, because it is the result of a sudden event with a specific cause. Whereas strokerelated brain injury is typically the result of a more complex and often chronic underlying disease process. TBI can be caused by a focal impact upon the head (e.g., being hit by a baseball), by a sudden acceleration and deceleration of the head (e.g., whiplash) or by a combination of both movement and impact (e.g., acceleration and deceleration associated with striking the windshield in a high speed auto accident). In addition to the damage caused at the moment of impact, secondary injury to the brain can be caused by alterations in cerebral blood flow and increased pressure within the skull related to bleeding within the skull and/or swelling of the brain. These secondary effects take place in the first hours or days after the initial injury, and contribute substantially to the resulting damage of the brain. TBI can be associated with a number of neurological, cognitive, social and behavioral effects, and outcome can range from complete recovery to permanent disability or death. TBI may be mild, moderate or severe. A mild injury is generally not serious and a full recovery, in a short order and without complications, is expected. A moderate injury may, more likely, result in more obvious impairment of, or brief loss of, consciousness and require a couple of weeks for full recovery. A severe injury may result in significantly altered mental activity, including coma, and may take weeks to months, or longer, for maximal recovery. Of note, repetitive mild or moderate brain injuries can have a cumulative effect in boxers, for example, with history of repetitive head trauma. For the purposes of this article we will focus on severe TBI. A severe TBI – like that suffered by Michael Schumacher – is a life threatening event, and studies have found mortality rates of 30-35 percent during the first six months. However, advances in neurosurgery and modern intensive care medicine have increased the chances to survive even severe TBI, and the improved probability of long-term survival is relevant for insurers. Over the last 20 years, the evidence on survival after moderate to severe TBI has grown with long-term follow-up studies of large groups. These studies are consistent in the identification of (a) age and (b) severity of ongoing functional disability as the most important clinical predictors of long-term survival. One of the most recent studies addressing the question of long-time survival after TBI comes from Brooks et al., and was published in 2013 in the Archives of Physical Medicine and Rehabilitation1. In this study, more than 7,000 patients admitted to hospitals with a TBI, and who survived for longer than one year post injury, were enrolled and followed for up to 20 years. The mean age at injury was 39 years and 73 percent were male. For the group, survival was poorer than that of the general population, with a standardized mortality ratio of 2.1 (an extra mortality of 110 percent). The major prognostic risk factors for survival was age and remaining functional disability. Munich Re Insurability after Severe Traumatic Brain Injury Page 2/2 The survivors who were largely independent from any assistance (with ADLs, IADLs, etc.) had a significantly better survival compared to those requiring mechanical aids or personal assistance. For those with minimal disability and being mainly independent, the estimated survival curve was slightly worse than that of typical 40-year-old man in the general population. The same may apply to disability covers. However, long term complications, especially sensory, behavioral and cognitive problems, may develop slowly years after the injury. Fully recovered survivors of severe TBI may often be accepted for disability products. However, a rated and/or limited benefit period policy might be appropriate to cover the risk for morbidity associated with long-term complications. For those at the severe end of the spectrum, who required 24-hour care, the estimated median survival time for a 40-year-old male was 13.4 additional years, that is, until age 53.4. In an Australian study2 from 2012, including 2,545 working-age adults with severe TBI being discharged from a rehabilitation center, mortality remained higher than the general population for many years. Again, functional disability was one of the main prognostic parameters, as discharge from rehabilitation to long term care facilities doubled the risk of mortality after TBI compared to those being discharged to home. The main causes of death in survivors of severe TBI are diseases of the respiratory and nervous system as well as mental and behavioral disorders. In underwriting individuals with history of TBI, it is important to take into account the current functional status of the applicant as this is a primary prognostic indicator. This would include any cognitive or neuro­ logical deficit, any remaining functional disability, history of respiratory problems, psychiatric disorders, substance abuse, etc. Applicants with minimal or no complications three years after a severe TBI can likely be accepted at low substandard to standard rates in highly favorable cases. For the assessment of sports and avocation risks, the tragic accident of Michael Schumacher reminds us that no active participant is immune from the risks of (extreme) sports or avocations, or, for that matter, the risks of daily living. It is assuring to know that, with modern emergency and intensive medical care and the growing use of protective gear (helmets, etc.), more and more people will likely survive severe TBIs. But the flip-side of this success is that, at the same time, more people will leave the hospital with long-term functional disabilities. It is important that underwriters understand the risks associated with severe TBI to properly assess the long-term mortality and morbidity risks associated with this injury. References 1 Brooks JC, Strauss DJ, Shavelle RM, Paculdo DR, Hammond FM, Harrison-Felix CL (2013). Long-term disability and survival in traumatic brain injury: Results from the National Institute on Disability and Rehabilitation Research Model Systems. Archives of Physical Medicine and Rehabilitation, 94:2203-2209. Baguley IJ, Nott MT, Howle AA, Simpson GK, Browne S, King AC, Cotter RE, Hodgkinson A (2012). Late mortality after severe traumatic brain injury in New South Wales: A multicentre study. Med J Aust. 2012 Jan 16;196(1):40-5. 2 Mark Skillan Vice President & Medical Director Munich American Reassurance Company Not if, but how © 2014 Munich American Reassurance Company, Atlanta, Georgia