ISMD2016 SCIENTIFIC PROGRAM THURSDAY, May 26, 2016 10.15 - 10.30 Opening Harald H. Kessler, President, ISMD2016 Alexander C. Haushofer, President, Austrian Society for Laboratory Medicine and Clinical Chemistry 10.30 - 12.30 Plenary Session Chairs: Alexander C. Haushofer, Harald H. Kessler 10.30 - 11.30 Children with HIV: risks and opportunities Nigel Klein, UCL Institute of Child Health and Great Ormond Street Hospital, London, UK 11.30 - 12.30 Th-17 cells - microbial translocation, immune activation, and exhaustion in HIV patients Deshratn Asthana, University of Miami – Miller School of Medicine, Miami, Florida, USA 12.30 - 14.30 Lunch Break / Industrial Exhibition / Poster View 14.30 - 16.00 New Technologies 1 Chairs: Hans-Joachim Burkardt, Evelyn Stelzl 14.30 – 14.45 Performance evaluation of the new real-time PCR-based cobas® HCV assay for use on the cobas® 6800/8800 systems for the detection and quantification of HCV RNA Johannes Vermehren, University Clinics Frankfurt/Main, Germany 14.45 - 15.00 Analysis of drug resistance associated mutations in HCV and HIV using Next Generation Sequencing Gerd Michel, Vela Research Ltd., Singapore 15.00 - 15.15 Towards standardized monitoring of HDV RNA viral load Ute Hofmann, Analytik Jena, Germany 15.15 - 15.30 Virological monitoring of bone marrow transplant patients Rolf Kaiser, University of Cologne, Germany 15.30 - 15.45 ® Molecular point-of-care diagnostics of influenza A and B by lab-in-a-tube testing – the cobas Liat system Willem J.G. Melchers, Radboud University Medical Centre, Nijmegen, The Netherlands 15.45 - 16.00 TM Multiplex detection of respiratory pathogens with GenMark’s ePlex sample-to-answer system Jochen Lips, GenMark Diagnostics, Zug, Switzerland 16.00 - 16.30 Coffee Break / Industrial Exhibition / Poster View 16.30 - 18.00 New Technologies 2 Chairs: Jörg Berg, Rodrig Marculescu 16.30 - 16.45 Efficient processing of complex test orders with an automated molecular diagnostics system Guido Adler, altona Diagnostics GmbH, Hamburg, Germany 16.45 - 17.00 Flexibility and full automation for clinical sample extraction – preliminary performance ® evaluation of the new bioMerieux eMAG Raphael Veyret, bioMérieux, Verniolle, France 17.00 - 17.15 Meet the diagnostic algorithm with modular tests – Zika virus included in the tropical panel Olfert Landt, TIB Molbiol, Berlin, Germany 17.15 - 17.30 Preanalytical requirements for the analysis of free circulating mitochondrial DNA Rene Zadnikar, Medical University of Vienna, Austria 17.30 - 17.45 Non-invasive prenatal testing by digital counting of fluorescently labeled DNA molecules Fredrik Dahl, Vanadis Diagnostics, a PerkinElmer company, Sollentuna, Sweden 17.45 - 18.00 Development of a new multiplex-based Real-Time RT-PCR assay for comprehensive detection of the four most common BCR-ABL breakpoint mutations Martin Svoboda, Bioproducts Mag. Th. Langmann GmbH, Stockerau, Austria FRIDAY, May 27, 2016 09.00 - 10.30 Pathogens – HCV, HIV Chairs: Bernhard Haas, Rudolf E. Stauber 09.00 - 09.25 Hepatitis C virus kinetics in the era of direct antiviral agents Johannes Vermehren, University Clinics Frankfurt/Main, Germany 09.25 - 09.50 Hepatitis C virus (HCV) screening project of patients on anti-HCV therapy Rolf Kaiser, University of Cologne, Germany 09.50 - 10.15 Screening for acute HIV infection: algorithms and cost-effectiveness Martin Hoenigl, University of California San Diego, California, USA 10.15 - 10.30 HIV and cardiovascular risk in a study population of mixed ancestry living in Cape Town, South Africa: preliminary data from the EndoAfrica study Hans Strijdom, Division of Medical Physiology, Stellenbosch University, Cape Town, South Africa 10.30 - 11.00 Coffee Break / Industrial Exhibition / Poster View 11.00 - 12.30 Pathogens – HPV, Respiratory/Gastrointestinal Viruses Chairs: Georg Mustafa, Brigitte I. Santner 11.00 - 11.30 HPV and p16/Ki-67 biomarker testing in routine: correlation with histology Hans Ikenberg, Cytomol, Laboratory for Cytology and Molecular Biology, Frankfurt, Germany 11.30 - 12.00 Point-of-Impact testing for respiratory viruses in the emergency room Hubert G. M. Niesters, University of Groningen, The Netherlands 12.00 - 12.30 Intra-individual noroviral evolution analyzed by next generation sequencing Dieter Hoffmann, Institute of Virology, TU Munich, Germany 12.30 - 14.30 Lunch Break / Industrial Exhibition / Poster View 14.30 - 16.00 HDV / Transfusion-related Pathogens Chairs: C. Micha Nuebling, Michael Chudy 14.30 - 15.00 How reliable is HDV RNA quantification? Michael Chudy, Paul-Ehrlich-Institute, Langen, Germany 15.00 - 15.30 Estimation of residual infection risks in blood components C. Micha Nuebling, WHO, Geneva, Switzerland 15.30 - 16.00 West Nile virus – an emerging virus leading to mandatory testing in transfusion? Christian Gabriel, Red Cross Transfusion Service for Upper Austria, Linz, Austria 16.00 - 16.30 Coffee Break / Industrial Exhibition / Poster View 16.30 - 18.00 Molecular Testing Systems for Rapid Detection of Bacteria and Antibiotic Resistance (including round table discussion) Chairs: Martin Altwegg, Georg Mustafa 16.30 - 16.45 The more, the better? Multiplex PCR for the detection of gastrointestinal pathogens Martin Altwegg, Bioanalytica AG, Lucerne, Switzerland 16.45 - 17.00 Rapid molecular detection of bacterial antibiotic resistance genes Guido V. Bloemberg, Unilabs, Dübendorf, Switzerland 17.00 - 17.15 The loss of controls – how to handle multiplex-PCR systems regarding positive and negative controls? Eva Leitner, Medical University of Graz, Austria 17.15 – 17.30 Molecular techniques for the diagnosis of prosthetic joint infection – is more less? Elisabeth Mustafa, medilab, Salzburg, Austria IMPORTANT NOTE FOR AUSTRIAN PARTICIPANTS / WICHTIGE MITTEILUNG FÜR ÖSTERREICHISCHE TEILNEHMER/INNEN Ab 18.00 Uhr Informationsveranstaltung zur Facharztprüfung aus Medizinischer und Chemischer Labordiagnostik fuer PrüfungskandidatInnen SATURDAY, May 28, 2016 09.30 - 11.30 Circulating Cell-Free DNA – Molecular Genetic Testing Chairs: Alexander C. Haushofer, Gregor Hörmann 09.30 - 10.00 Cell-free circulating DNA as a new tool for screening fertility issues, fetal rhesus and tumor treatment follow-up Pierre-Alain Menoud, Unilabs Lausanne, Switzerland 10.00 - 10.30 Liquid profiling – new perspectives for prediction and monitoring of therapy response in cancer patients Stefan Holdenrieder, University Hospital Bonn, Germany 10.30 - 11.00 Phenotypic alterations in relation to cytogenetics in acute lymphoblastic leukemia Janos Kappelmayer, University of Debrecen, Hungary 11.00 – 11.30 Implementation of v-natal® non-invasive prenatal testing for the detection of trisomies and gonosomal aneuploidies: a Swiss private laboratory experience Christoph Noppen, Viollier AG, Basel, Switzerland 11.30 - 12.00 ISMD2016 Best Poster Award Chairs: Deshratn Asthana, Alexander C. Haushofer POSTER SESSIONS THURSDAY, May 26, 2016 (poster walk 13.30 through 14.30) & FRIDAY, May 27, 2016 (poster walk 13.30 through 14.30) All presenters must be present for discussion during poster walks