Hosea M. Nelson, Ph.D.
College of Chemistry, UC Berkeley
Berkeley, CA 94720
Phone: (510) 375-7866; email: hosea@berkeley.edu
Education
California Institute of Technology (2006-2012)
Ph.D. Synthetic Organic Chemistry
(Advisor: Professor Brian M. Stoltz)
University of California at Berkeley (2002-2004)
B.S. in Chemistry
City College of San Francisco (1998-2002)
Science and Math Major
Research Positions
University of California at Berkeley (2012-present)
Postdoctoral Fellow (Advisor: Professor F. Dean Toste)
Topic: Chiral Anion Phase-Transfer
University of California at Riverside (2012)
Visiting Scholar (Advisor: Professor Vincent Lavallo)
Topic: Carborane Containing Organometallic Complexes
California Institute of Technology (2007-2012)
Graduate Research Assistant (Advisor: Professor Brian M. Stoltz)
Topic: Total Synthesis
Panasonic Energy Solutions Lab (2004-2006)
Research Assistant
Topic: Lithium Ion Batteries and Methanol Fuel Cells
San Francisco State University (2000-2002)
Undergraduate Research Assistant (Advisor: Leticia Marquez-Magaña)
Topic: Microbial Genetics
Academic Honors
UNCF/Merck Postdoctoral Fellowship (2012)
NSF Predoctoral Fellowship (2007)
Ford Foundation Predoctoral Fellowship (2007)
Hertz Fellowship Honorable Mention (2007)
Caltech Institutional Fellowship (2006)
NIH Bridges to Baccalaureate Fellow (CCSF/SFSU, 2000)
Thomas Hynes Scholarship (CCSF, 2000)
Teaching
University of California at Berkeley Teaching Assistant (2004)
Classes: Chemistry 112b Upper division Undergraduate Organic Chemistry
California Institute of Technology Graduate Student Instructor (2008-2011)
Classes: Chemistry 242ab, Graduate Level Organic Chemistry
Publications
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‡
1.
Nelson, H. M. ; Williams, B. D. ; Miró, J.; Toste, F. D. “Enantioselective 1,1-Arylborylation of Alkenes: Merging
Chiral Anion Phase Transfer with Pd Catalysis” J. Am. Chem. Soc. 2015, DOI: 10.1021/jacs.5b00344, published
online February 27, 2015.
2.
Gordon, J. R.; Nelson, H. M.; Virgil, S. C.; Stoltz, B. M. “The Total Syntheses of Basiliolide C, epi-Basiliolide C,
and Protecting-Group-Free Total Syntheses of Transtaganolides C and D,” J. Org. Chem. 2014, 7, 9740–9747.
3.
Nelson, H. M. ; Patel, J. S. ; Shunatona, H. P.; Toste, F. D. “Enantioselective α-Amination Enabled by a BINAMDerived Phase-Transfer Catalyst” Chem. Sci. 2014, 6, 170–173.
4.
Nelson, H. M.; Reisberg, S. H.; Shunatona, H. P.; Patel, J. S.; Toste, F. D. “Chiral Anion Phase-Transfer of
Aryldiazonium Cations: An Enantioselective Synthesis of C3-Diazenated Pyrroloindolines” Angew. Chem. Int. Ed.
2014, 53, 5600–5603.
5.
Vieregg, J. R.; Nelson, H. M.; Stoltz, B. M.; Pierce, N. A. “Selective Nucleic Acid Capture With Shielded Covalent
Probes,” J. Am. Chem. Soc. 2013, 135, 9691–9699.
6.
Nelson, H. M.; Gordon, J. R.; Virgil, S. C.; Stoltz, B. M. “Total Syntheses of (–)-Transtaganolide A, (+)Transtaganolide B, (+)-Transtaganolide C, and (–)-Transtaganolide D and Biosynthetic Implications,” Angew.
Chem. Int. Ed. 2013, 52, 6699–6703.
7.
Nelson, H. M.; Murakami, K.; Virgil, S. C.; Stoltz, B. M. “A General Approach to the Basiliolide/Transtaganolide
Natural Products: Total Syntheses of Basiliolide B, epi-8-Basiliolide B, Transtaganolide C, and Transtaganolide
D,” Angew. Chem. Int. Ed. 2011, 8, 3688–3691.
8.
Nelson, H. M.; Stoltz, B. M. “Progress Toward the Synthesis of the Transtaganolide/Basiliolide Natural Products:
An Ireland-Claisen Approach,” Tetrahedron Lett. 2009, 50, 1699–1701.
9.
Sun, Q.; Nelson, H. M.; Ly, T.; Stoltz, B. M.; Julian, R. R. “Side Chain Chemistry Mediates Backbone
Fragmentation in Hydrogen Deficient Peptide Radicals,” J. Proteome Res. 2009, 8, 958–966.
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10. Nelson, H. M.; Stoltz, B. M. “Progress toward the Synthesis of the Basiliolides and Transtaganolides: An
Intramolecular Pyrone Diels-Alder Entry into a Novel Class of Natural Products,” Org. Lett. 2008, 10, 25–28.
Patents
1.
Nelson, H. M.; Murakami, K.; Gordon, J. R.; Virgil, S. C.; Stoltz, B. M. “Synthetic transtaganolide and basiliolide
products, derivatives thereof, and synthesis methods,” United States Patent US 13/353314, 2012.
Invited Presentations/Outreach
1.
“The Merging of Chiral Anion Phase-Transfer and Classical Heck–Matsuda Cross-coupling” Merck Rahway, NJ
(2015)
2.
“A General Approach to the Basiliolide/Transtaganolide Natural Products and the Development of Asymmetric
C–C and C–N Bond Forming Reactions via Phase-Transfer Catalysis,” Organic Chemistry Seminar, San Jose
State University (2014)
3.
“From CCSF to Postdoctoral Studies: Life, Liberty, and the Pursuit of Natural Products," NIH Bridges Seminar,
City College of San Francisco (2013)
4.
“A General Approach to the Basiliolide/Transtaganolide Natural Products,” Inorganic-Organometallics Seminar,
Caltech (2011)
Professional Organizations
1.
American Chemical Society (ACS)
2.
The Association of Underrepresented Minority Fellows (AUMF)
References
1.
Professor Brian M. Stoltz, California Institute of Technology, stoltz@caltech.edu, (626)-395-6064
2.
Professor Robert H. Grubbs, California Institute of Technology, rhg@caltech.edu, (626)-395-6003
3.
Professor F. Dean Toste, UC Berkeley, fdtoste@berkeley.edu, (510)-642.2850
4.
Professor Sarah E. Reisman, California Institute of Technology, reisman@caltech.edu, (626)-395-4004