wssfn World Society for Stereotactic and Functional Neurosurgery WSSFN Quadrennial Meeting May 27-30, 2013 Hotel Nikko Tokyo Tokyo, Japan Jointly sponsored by the: American Association of Neurological Surgeons (AANS) in collaboration with the: Japan Brain Foundation and the Tokyo Convention & Visitors Bureau Supported by the Japanese Neurological Society www.wssfn.org wssfn World Society for Stereotactic and Functional Neurosurgery Dear Colleagues and Guests of the WSSFN, ic and Functional of the World Society for Stereotact ting Mee l nnia dre Qua h 16t the Welcome to ntific program other WSSFN officers, and my scie a, Tair i aom Tak nt, side pre iety Neurosurgery! Our soc are sure will be of great me to prepare a program that we with ked wor all e hav aie Hod ji co‑chair Mo ussion. interest and stimulate much disc s on stereotactic and all know there is an intense focu you As . SFN WS the for e tim This is a most exciting edge of this wave. Since our last and our society is on the leading r, ove ld wor the ery urg ros neu the American functional ed the WSSFN as par tners (joining join N SSF an ope Eur the 9 200 meeting in Toronto in May our official journal, Stereotactic atly expanded the readership of gre has also This ). ard reg this society in er the editorial impact factor continue to rise und and ity ctiv sele se who y, rger and Functional Neurosu ember 2011 was a great rim meeting in Cape Town in Nov inte last Our . erts Rob id Dav of leadership s for our nex t event in two years. success, and we invite suggestion gestions after the prior meeting s not occur in a vacuum. Your sug Planning the WSSFN program doe cess of those two sessions in wanted more debates after the suc You t. oun acc into n take ch mu were ver y during lunch. More , three on each day of the meeting ates deb Box to Ben nine are e Toronto? This year ther in based on WSSFN member tric neurosurgery was added, aga chia psy and ry rge iosu rad to first two meeting time devoted l plenary session at the end of the fina a is m gra pro r’s yea this of feedback. A new feature orous discussion by all c program will be summarized. Vig ntifi scie the of s ure feat key ch days in whi sessions. attendees is encouraged at these but to have sions this year, we had no choice mis sub t trac abs of ber num ing Due to the record-break ter display. Some of the most to the scheduled day for your pos ere adh se Plea s. sion ses ter pos separate to view these and , so please use the available time ters pos the in is n ofte s ting mee interesting work at our d plenary session and, lastly, will conclude with a distinguishe ting mee The . ors auth the with t to interac dents and fellows. l and poster presentations by resi the awards ceremony for best ora should consider er at the meeting. First-time visitors dinn gala and n ptio rece ning You will enjoy the ope s. Take it from a gaijin, Tok yo ting, to see the city and its environ mee the r afte or re befo e, tim e adding som e easy to navigate. safe cities in the world, and quit is one of the most interesting and ts on the meeting . Please let us know your though SFN WS the of t por sup r you for Thanks for coming and all it takes is enthusiasm and Your involvement is welcome and w. gro to e tinu con we as iety and the soc commitment! Sincerely yours, Michael Schulder, MD retary-Treasurer, WSSFN Scientific Program Chair and Sec wssfn Faculty World Society for Stereotactic and Functional Neurosurgery MEETING DIRECTORS Takaomi Taira - Meeting Chairman Michael Schulder - Scientific Program Chairman Mojgan Hodaie - Scientific Program Co-chair Joseph Neimat - Meeting Industry Relations Chairman Joachim Krauss - Meeting Co-chairman Jin Woo Chang - Meeting Co-chairman Hiroki Toda - Meeting Co-chairman/Pre-meeting Symposium Chairman Osvaldo Vilela Filho - Meeting Co-chairman SPEAKERS AND MODERATORS Aviva Abosch University of Minnesota Department of Neurosurgery Minneapolis, USA Feridun Acar Pamukkule University Denizli, Tukey Ahmed Alkhani King Faisal Specialist Hospital and Research Centre Riyadh, Saudi Arabia Ron L. Alterman Beth Israel Deaconess Medical Center Boston, USA Jeffrey Arle Beth Israel Deaconess Medical Center Boston, USA Tipu Aziz Radcliffe Infirmary Department of Neurosurgery Oxford, UK Roy Bakay Rush University Medical Center Chicago, USA Gordon Baltuch University of Pennsylvania School of Medicine Philadelphia, USA Juan Barcia Hospital Clínico San Carlos Madrid, Spain Alim Benabid Clinatec CEA Grenoble Meylan, France Tommy Bergenheim Umea University Umea, Sweden Mark Bernstein University of Toronto Toronto, Canada Jocelyne Bloch Brian Brophy Royal Adelaide Hospital Adelaide, Australia Stephan Chabardes University Hospital of Grenoble Grenoble, France Jin Woo Chang Yonsei University College of Medicine Seoul, South Korea Mikhail Chernov UCLA Neurosurgery Department Los Angeles, USA Paresh Doshi Jaslok Hospital and Research Centre Mumbai, India Larry Chin Jeff Elias Volker Coenen Sam Eljamel SUNY Upstate Medical Center Syracuse, USA Freiburg University Medical Center Freiburg (i.Br.), Germany Youssef Comair Gilbert and Rose-Marie Chagoury School of Medicine Beirut, Lebanon Philippe Cornu Hôpital Pitié-Salpêtrière Paris, France Rees Cosgrove Rhode Island Hospital OR Lifespan Providence, RI Terry Coyne St Andrews and Wesley Hospitals Auchenflower, Australia Jeff Cozzens Southern Illinois University School of Medicine Springfield, USA Arthur Cukiert Clinica de Epilepsia de Sao Paulo Sao Paulo, Brazil Isao Date Patric Blomstedt Phillipe Decq Instituto Nazionale Neurologico Milano, Italy Antonio De Salles Wilhelm Eisner University Hospital of Lausanne Lausanne, Switzerland Giovanni Broggi Ohio State University Medical Center Columbus, USA Tokyo Women’s Medical University Tokyo, Japan Okayama University Medical School Okayama, Japan University Hospital of Umea Umea, Sweden Milind Deogaonkar Hopital Beaujon Paris, France Medical University, Innsbruck Innsbruck, Austria University of Virginia Charlottesville, USA Steven Gill Frenchay Hospital Bristol, UK Robert Goodman Roosevelt Hospital Columbia University College of Physicians and Surgeons New York, USA Alexander Green Oxford Functional Neurosurgery and Experimental Neurology Oxford, UK Robert Gross Emory University Atlanta, USA Jorge Guridi Clinica Universitaria Pamplona, Spain Ninewells Hospital and Medical School Dundee, UK Clement Hamani Emad Eskandar Marwan Hariz Harvard Medical School Massachusetts General Hospital Boston, USA Graham Fieggen Toronto Western Hospital Toronto, Canada Institute of Neurology London, UK Motohiro Hayashi University of Cape Town Cape Town, South Africa Tokyo Women’s Medical University Tokyo, Japan Denys Fontaine Mojgan Hodaie Centre Hospitalier Universitaire de Nice Nice, France Kostantinos Fountas University of Thessaly, School of Medicine Terpsithea-Larisa, Greece Alexandre Francisco Hospital Universitário Cajuru Pontifical Catholic University Curitiba, Brazil Angelo Franzini Besta Neurological Institute Milan, Italy Itzhak Fried Ronald Reagan UCLA Medical Center Los Angeles, USA Miroslav Galanda Roosevelt Hospital Banska Bystrica, Slovokia University of Toronto Toronto, Canada Christopher Honey Vancouver General Hospital Vancouver, Canada Tomokatsu Hori Tokyo Women´s Medical University Tokyo, Japan Zvi Israel Hadassah University Hospital Jerusalem, Israel Ben Jonker Brain and Mind Research Institute University of Sydney, Australia Michael Kaplitt Weill Cornell Medical College New York, USA Yoichi Katayama Nihon University School of Medicine Tokyo, Japan WSSFN Quadrennial Meeting 2013 Kensuke Kawai University of Tokyo Tokyo, Japan Takeshi Kawase Keio University School of Medicine Tokyo, Japan Yoshihisa Kida Komaki City Hospital Komaki City, Japan Moon Chan Kim Kangnazm St. Mary’s Hospital Seoul, Korea Zelma Kiss University of Calgary Calgary, Canada Masahito Kobayashi Saitama Medical University Saitama, Japan Takeshi Kondoh Shinsuma General Hospital Kobe, Japan Brian Harris Kopell Icahn School of Medicine The Mount Sinai Hospital New York City, USA Joachim Krauss Medical University of Hannover Hannover, Germany Paul Larson UCSF Medical Center San Francisco, USA Jung Kyo Lee Department of Neurosurgery Asan Medical Center Seoul, South Korea Bengt Linderoth Karolinska University Hospital Stockholm, Sweden Christer Lindquist Bupa Cromwell Hospital London, UK Nir Lipsman University of Toronto Toronto, Canada Andres Lozano University of Toronto Toronto, Canada Guoming Luan Sanbo Brain Institute Beijing, China Goetz Lutjens Medical School Hanover Hanover, Germany Andre Machado Center for Neurological Restoration Cleveland Clinic Cleveland, USA George Mandybur University of Cincinnati Medical Center Mayfield Clinic Cincinnati, USA Keith Matthews University of Dundee Ninewells Hospital and Medical School Dundee, Scotland Paolo Mazzone ASLRMC-CTO Hospital Roma, Italy Maximilian Mehdorn Christian-Albrechts University of Kiel Kiel, Germany Bjorn Meyerson Karolinska Hospital Stockholm, Sweden Alon Mogilner NYU Langone Medical Center New York City, USA Elena Moro Jean Regis Hôpital d’adulte de la Timone Marseille, France Ali Rezai The Ohio State University Columbus, USA Erich Richter Louisiana State University School of Medicine New Orleans, USA David Roberts Dartmouth Hitchcock Medical Center Lebanon, USA Pantaleo Romanelli Besta Neurological Institute Milan, Italy Jeffrey Rosenfeld CHU, Joseph Fourier University Grenoble, France Alfred Hospital and Monash University Victoria, Australia Nobukazu Nakasato Sally Rothemeyer Tohoku University School of Medicine Sendai, Japan Atsushi Nambu National Insitute for Physiological Sciences Okazaki, Japan Jules Nazzaro University of Kansas School of Medicine Kansas City, USA Joseph Neimat Vanderbilt University Medical Center Nashville, USA Wai Hoe Ng National Neuroscience Institute Singapore Bart Nuttin U.Z. Gasthuisberg Leuven, Belgium Taku Ochiai Ochiai Neurological Clinic Saitama, Japan Sun Ha Paek Seoul National University Hospital Seoul, South Korea Erica Petersen University of Arkansa for Medical Sciences Little Rock, USA Fabian Piedimonte School of Medicine of the University of Buenos Aires Buenos Aires, Argentina Julie Pilitsis Albany Medical Center Albany, USA Claudio Pollo Centre Hosptalier Universitaires Vaudois Lausanne, Switzerland Dheerendra Prasad Roswell Park Cancer Institute Buffalo, USA University of Cape Town Cape Town, South Africa Oren Sagher University of Michigan Health Center Ann Arbor, USA Damianos Sakas Evangelismos Hospital Athens, Greece Tejas Sankar University of Alberta Edmonton, Canada Gaston Schechtmann Karolinska Institutet and University Hospital Stockholm, Sweden Michael Schulder Hofstra North Shore LIJ School of Medicine Manhasset, USA Rick Schuurman Academic Medical Center Amsterdam, Netherlands Toru Serizawa Tsukiji Neurological Clinic Tokyo, Japan Vladimir Shabalov Burdenko Neurosurgical Institute Moscow, Russia Ashwini Sharan Thomas Jefferson University Hospital Philadelphia, USA Karl Sillay University of Wisconsin Hospital and Clinics Madison, USA Marc Sindou Hospital Neurologique Pierre Wertheimer University of Lyon Lyon, France Konstantin Slavin University of Illinois College of Medicine at Chicago Chicago, USA Byung-chul Son Seoul St. Mary’s Hospital The Catholic University of Korea Seoul, South Korea Roberto Spiegelmann Chaim Sheba Medical Center Tel Hashomer, Israel Bomin Sun Shanghai Jiao Tong University Rui Jin Hospital Shanghai, China Takaomi Taira Tokyo Women’s Medical University Tokyo, Japan Manoel Teixeira Hospital Das Clínicas University of Sao Paulo Medical School Sao Paulo, Brazil Travis Tierney Brigham and Women’s Hospital Boston, USA Hiroki Toda Tazuke Kofukai Medical Research Institute and Kitano Hospital Osaka, Japan Francisco Velasco Hospital General de Mexico O.D. Mexico City, Mexico Osvaldo Vilela-Filho Goiania Neurological Institute and Medical Center Federal University of Gioas Goiania, Brazil Ashwin Viswanathan Baylor College of Medicine Houston, USA Eiju Watanabe Jichi Medical University Tochigi, Japan Donald Whiting Allegheny West Penn Health System Pittsburg, USA Hemmings Wu Katholieke Universiteit Leuven Leuven, Belgium Masaaki Yamamoto Katsuta Hospital Hitachi-naka, Japan Wade Huai-che Yang Taipei Veterans General Hospital Taipe, Taiwan Ludvic Zrinzo UCL Insitute of Neurology National Hospital for Neurosurgery and Neurology London, UK wssfn Monday, May 27, 2013 World Society for Stereotactic and Functional Neurosurgery Monday, May 27, 2013 1:00 - 5:00 PM Workshop S1 International Satellite Symposium on Neuro‑ surgery for Psychiatric Disorders Tokyo International Exchange Center - Heisei Plaza Workshop S2 Microrecording and Intraoperative Monitoring Tokyo International Exchange Center- Heisei Plaza 6:30 - 9:00 PM Opening Reception: Promenade Deck Hotel Nikko Tuesday, May 28, 2013 Registration Continental Breakfast in meeting rooms 7:15 - 8:15 AM PEGASUS AB1 PEGASUS C APOLLON Breakfast Seminar I: High Intensity Focused Ultrasound Breakfast Seminar II: Pedunculopontine Neucleus: A Real Target? Breakfast Seminar III: Clinical Trials in Functional Neurosurgery Moderators: Byung Chul Son/M. Sam Eljamel Moderators: Paolo Mazzone/Ludvic Zrinzo Moderators: Alexander Green/Antonio DeSalles • HIFU for Pain: Nir Lipsman • Where is the PPN: Tipu Aziz • Movement disorders: Angelo Franzini • Movement Disorders: Jin Woo Chang • Clinical Results: Terry Coyne • Tumors: Jeffrey Elias • A Skeptical Note: Feridun Acar • Psychiatric Neurosurgery: Keith Matthews Breakfast Seminars 7:00 AM • Surgery for Memory Enhancement: Andres Lozano 8:30 - 9:00 AM 9:00 - 9:10 AM Plenary Session I PEGASUS AB1 Plenary Session I: Emerging Technologies Presidential Address Takaomi Taira In Memoriam: Prof. Fritz Mundinger Joachim Krauss 9:10 - 9:30 AM Keynote Address: From Lesioning to DBS and Beyond Andres Lozano 9:30 - 10:30 AM Papers (4 papers - 8 minute presentations - 5 minute discussions) Moderators: Joachim Krauss/Michael Schulder 9:30-9:43: MR-guided Focused Ultrasound Thalamotomy for Essential Tremor - one year results (309) W. Jeff Elias 9:45-9:58: Stereotactic Implantation of Cells Secreting Nerve Growth Factor (NGF) in the Basal Forebrain of Alzheimer Patients: Update With Improved Cell Line (281) Bengt Linderoth 10:30 - 10:50 AM 10:00-10:13: Optical Imaging of Inter-areal Connectivity Evoked by Electrical Stimulation in Somatosensory and Motor Cortices (410) Katherine Kudyba 10:15-10:28: Implanted Brain Computer Interface as a Neurofeedback System for Neurorehabilitation (204) Vincent Roualdes Refreshment Break - View Posters & Exhibits - MEETING ROOM FOYER Tuesday, May 28, 2013 Papers (4 papers - 8 minute presentations - 5 minute discussions) 10:50 - 11:50 AM Moderators: Jeffrey Arle/Max Mehdorn 10:50-11:03: Progress in Bionic Vision Devices (19) Jeffrey Rosenfeld 11:05-11:18: Stereotactic Laser Ablation of Epileptic Foci: A Novel, Minimally Invasive Technique for Intractable Epilepsy (333) Jon T. Willie 11:20-11:33: Bone Marrow Stem Cells Intraspinal Infusion Technique as a Part of a Pilot Study in ALS (351) Pedro de la Rosa Jimenez 11:35-11:48: New Tactics for Treatment of Sensorineural Hearing Loss (161) Jin Woo Chang Spiegel and Wycis Awards Presented by Takaomi Taira and Joachim Krauss Noon - 1:30 PM PEGASUS AB1 PEGASUS C APOLLON Bento Box Debate I: The Future of Ablative Neurosurgery Bento Box Debate II: Surgery for Depression: Which Site? Bento Box Debate III: Stimulation for Epilepsy: Which Site? Moderators: Erica Petersen/ Vladimir Shabalov Moderators: Brian Kopell/ Paresh Doshi Moderators: David Roberts/ Stephan Chabardes • SRS: Christer Lindquist • Area 25: Clement Hamani • Hippocampus: Francisco Velasco • HIFU: Jin Woo Chang • Nucleus Accumbens: Andre Machado • Thalamic: Gordon Baltuch • LITT: Michael Schulder • Dorsolateral PFC: Emad Eskandar • Vagus: Kensuke Kawai PEGASUS AB1 PEGASUS C APOLLON Afternoon Session I: Movement Disorders Afternoon Session II: Epilepsy Afternoon Session III: Radiosurgery 1:30 - 2:00 PM Keynote Address: Lesioning, a 21st Century Treatment for Movement Disorders Takaomi Taira Keynote Address: Epilepsy Surgery and the Mind Itzhak Fried Keynote Adress: Radiosurgery Recent Trends in Stereotactic Radiosurgery for Multiple Brain Metastases Masaaki Yamamoto 2:00 - 3:00 PM Papers (5 papers - 7 minute presentations 3 minute discussions) Papers (5 papers - 7 minute presentations 3 minute discussions) Papers (5 papers - 7 minute presentations 3 minute discussions) Moderators: Michael Kaplitt/ Christopher Honey Moderators: Ashwini Sharan/Youssef Comair Moderators: Larry Chin/Toru Serizawa 2:00-2:10: Magnetic Resonance Guided Focused Ultrasound for Unilateral Thalamotomy in Medication Refractory Essential Tremor (28) Nir Lipsman 2:00-2:10: Five Hundred Stereoelectroencephalography Procedures for Presurgical Invasive Evaluation of Drug-resistant Epilepsy: Efficiency, Safety, Application Accuracy and Outcome on Seizures (83) Francesco Cardinale Afternoon Sessions Bento Box Debates 11:50 - Noon 2:12-2:22: High Frequency Stimulation at GPi Modulates GFRα1b, CAMK2A and GAD1 Gene Expression (145) Xun Kiat Ho 2:24-2:34: Health Economics and Surgical Treatment for Parkinson’s Disease in a World Perspective (312) Gaston Schechtman 2:36-2:46: Double-Blind Comparison of Intraoperative Subthalamic High Frequency, Low Frequency and Sham Stimulation Effects on Verbal Fluency (311) Alexander I. Troster 2:48-2:58: Involvement of Pedunculopontine (PPN) and Cuneiform Nuclei (CfN) in Bipedal Locomotor Behavior: Electrophysiological Study in Normal and Parkinsonian (MPTP) Primate (291) Laurent Goetz 3:00 - 3:30 PM 2:12-2:22: Stimulation of the Anterior Nucleus of the Thalamus for Epilepsy (SANTE) Trial: Results Related to Region of Onset and Prior Surgical Treatments (237) Robert E. Gross 2:24-2:34: Improved Seizure Outcomes in Resections Involving the Orbito-frontal Cortex: Evidence for “Orbito-frontal-plus” Epilepsy (91) Demitre Serletis 2:36-2:46: Results of Surgery for Refractory Epilepsy: Highlights From a Series of 1696 Patients Submitted To Surgery (102) Arthur Cukiert 2:48-2:58: Electrocorticographic Evidence of Different Physiopathologic Types in Mesial Temporal Epilepsy. Surgical Implications (139) Cristina V. Torres Refreshment Break - View Posters & Exhibits - Meeting Room Foyer 2:00-2:10: Clinician Preferences in Management of Trigeminal Neuralgia - A survey of Australian Neurosurgeons and Neurologists (164) Benjamin P. Jonker 2:12-2:22: A New Grading System Focusing on Functional Preservation for Brain Metastasis Patients Treated With Stereotactic Radiosurgery (35) Toru Serizawa 2:24-2:34: Time Delayed Contrast Enhanced MRI Improves Detection of Brain Metastases (352) Michael Schulder 2:36-2:46: Delayed Contrast Extravasation MRI Differentiates Metastatic Tumor Progression from Radiation Necrosis after Radiosurgery (172) Roberto Spiegelmann 2:48-2:58 Long Term Result of Gamma Knife Treatment for Prolactinomas (73) Peng Li wssfn Tuesday, May 28, 2013 3:30 - 4:30 PM World Society for Stereotactic and Functional Neurosurgery PEGASUS AB1 PEGASUS C APOLLON Flash presentations Flash presentations Flash presentations (15 papers, 3 minutes each) (15 papers, 3 minutes each) (15 papers, 3 minutes each) Moderators: Hemmings Wu/ Fabian Piedimonte Moderators: Arthur Cukiert/ Jung Kyo Lee Moderators: Yoshihisa Kida/ Jean Regis 3:30-3:33: Saccadic modulation with Concomitant Subthalamic nucleus and Pedunculopontine nucleus-stimulation in advanced Parkinson’s disease (226) Mohammad Nausahi 3:30-3:33: Functional Connectivity Observed in Partial Epilepsy With Automotor Seizure (240) Hiroki Nishibayashi 3:30-3:33: Fractionated Stereotactic Radiosurgery for Intracranial Metastases: Tumor Control (304) Michael Schulder 3:34-3:37: Posterior Cingulate Epilepsy: Clinical and Neurophysiological Analysis (107) Rei Enatsu 3:34-3:37: Magnetic Resonance Diffusionweighted Imaging for Targeting Glioma in Stereotactic Biopsy: A Correlative Study with Histopathological Examination and Clinical Outcome (117) Yi-Chieh Hung 3:34-3:37: Anatomical Study of the Pedunculopontine Nucleus in Humans: Where Is the PPN? (365) Takashi Kawasaki 3:38-3:41: Dorsal Versus Ventral Stn Stimulation Effects on the Inhibition of Action Impulses (415) Nelleke van Wouwe 3:42-3:45: Can Low Frequency Stimulation At Subthalamic Area Improve the Motor Performance of Patients With Parkinson’s Disease? (163) Chiung Chu Chen 3:47-3:50: Validation of the Electrodes’ Location by Probabilistic Tractography in Parkinson’s Disease Patients Who Underwent Bilateral Subthalamic Deep Brain Stimulation (DBS) Surgery (322) David Kis 3:51-3:54: Different Targets for Different Patients’ Profile: how to modulate DBS for Parkinson’s Disease (347) Andrea Landi 3:55-3:58: State Changes in Subthalamic Nucleus Neurons: Implications for Motor Circuits and Deep Brain Stimulation Surgery (295) Robert M. Brownstone 3:59-4:02: Striatal-transplantation of Dopamine Neurons in Parkinson Rat Model: Subthalamic Nucleus Neuronal Activity and Gene Expression (198) Mesbah Alam 4:03-4:06: The Role of Connectivitybased Thalamic Segmentation in the Surgical Targeting in Tremor Patients (329) Adrienn Maté 4:07-4:10: Long Term Assessment of Functional Consequences of 150 Tibial Neurotomies for Treatment of Spastic Foot (305) Patrick Mertens 4:11-4:14: FDG-PET Study of Cerebral Glucose Metabolic Changes After Thalamotomy in Patients With Essential Tremor (120) Takaaki Miyagishima 3:38- 3:41: Extra-temporal Resection in Refractory Epilepsy (103) Arthur Cukiert 3:42-3:45: Efficacy of Vagal Nerve Stimulation in the Treatment of Infantile Spasms: Effects of Different Tuning and Stimulation Cycles (346) Andrea Landi 3:46-3:49: Development of Focal Brain Cooling System for the Treatment of Intractable Epilepsy (348) Masami Fujii 3:50-3:53: Intra-operative Monitoring of Inter-hemispheric EEG Connectivity During Corpus Callosotomy (100) Masaki Iwasaki 3:54-3:57: Subtemporal Amygdalohippocampectomy for Medial Temporal Eplepsy. Operative Results and Neuropathological Findings (15) Tomokatsu Hori 3:58-4:01: Risk of Epilepsy After Traumatic Brain Injury: A Retrospective Population-based Cohort Study (16) Chien-Chang Liao 4:02-4:05: A Novel Electrode Array for Electrocorticography of the Temporal Pole (153) Hiroto Kawasaki 4:06-4:09: Radiosurgery for Intractable Seizure Associated With Various Brain Disorders (143) Yoshihisa Kida 4:10-4:13: Surgical Treatment Options for Adults With Lesional and NonLesional Epilepsies (146) Andrey R. Sitnikov 4:14-4:17: Outcome After More Than Two Year of Temporal Lobe Epilepsy Surgery With Stereoeeg (407) Taku Ochiai 4:22-4:25: Bilateral Caudal Zona Incerta Deep Brain Stimulation for Parkinson’s Disease (85) Patric Blomstedt 4:40 - 5:30 PM Plenary Session 4:26-4:29: Effect of subthalamic nucleus stimulation during exercise on the mesolimbocorital dopaminergic region in Parkinson’s disease: A positron Emission Tomography Study (25) Takao Nozaki PEGASUS AB1 Plenary Session: Scientific Highlights and Discussion, Day 1 Moderators: Robert Goodman/Sun Ha Paek Discussants: George Mandybur/Tejas Sankar 3:38- 3:41: Radiographic Evolution of Thalamotomy Lesions Generated by Stereotactic Radiosurgery: A Two-Year Follow-up (387) Anand I. Rughani 3:42-3:45: Interstitial Brachytherapy With Iodine-125 Seeds for Low Grade Brain Stem Gliomas in Adults: Diagnostic and Therapeutic Intervention in a One-step Procedure (193) William Ol. Contreras Lopez 3:46-3:49: Long-term Outcomes of Gamma Knife Surgery for Classic Trigeminal Neuralgia in Patients Younger Than 50 Years (245) Jung Kyo Lee 3:50-3:53: A Preliminary Result of the Prospective Control Study of Gamma Knife Radiosurgery for Trigeminal Neuralgia With One Or Two Isocenters (259) Peng Li 3:54-3:57: Gamma Knife Radiosurgery as a complementary treatment of large vestibularis schwannomas (255) Etienne Holl 3:58-4:01: Staged Gamma Knife Radiosurgery for Relatively Large Metastatic Brain Tumors (257) Atsuya Akabane 4:02-4:05: Long Term Results of Gamma Knife Radiosurgery for Craniopharyngioma (341) Huai Cehe Yang 4:06-4:09: Proposed Mechanism and Treatment Strategy for Cyst Formation and Enlargement Following Gamma Knife Surgery for Arteriovenous Malformation (148) Takashi Shuto 4:10-4:13: Hydrocephalus following Gamma Knife Radiosurgery in the Vestibular Schwannoma (132) Kyoung-Hyup Nam (4:14-4:17: GKS for Cervical Spinal Cord Tumors (64) Mooseong Kim 4:18-4:21: Clinical Application of the Verification Method of Leksell Gamma Plan in Multiple Metastatic Brain Tumors (162) Beong Ik Hur 4:22-4:25: Complications of Radiosurgery for Tic in Patients With MS (334) Keith Gomes 4:26-4:29: Validity Test of the Modified Recursive Partitioning Analysis for Brain Metastases Cases from Breast Cancer Treated Radiosurgically (178) Osamu Nagano Wednesday, May 29, 2013 Wednesday, May 29, 2013 Continental Breakfast in Meeting Rooms 7:15 - 8:15 AM PEGASUS AB1 PEGASUS C Breakfast Seminar IV: Restorative Neurosurgery Breakfast Seminar V: Functional Stereotactic Radiosurgery Moderators: Wade Yang/Jeff Cozzens Moderators: Yoshihisa Kida/Joseph Neimat Breakfast Seminars 7:00 AM • Gene Therapy: Michael Kaplitt • Stem cells: Roy Bakay • Transplantation: Jocelyn Bloch APOLLON • Movement Disorders: Larry Chin • Psychiatric Disorders: Rees Cosgrove • Pain: Motohiro Hayashi Breakfast Seminar VI: Surgical Treatment of Head and Facial Pain Moderators: Tomokatsu Hori/ Manoel Teixeira • Cluster Headaches: Denys Fontaine • Occipital Nerve Stimulation: Oren Sagher • Advanced Imaging in Trigeminal Neuralgia: Mojgan Hodaie PEGASUS AB1 Plenary Session II: Best Science Welcome Michael Schulder 8:35 - 9:00 AM Keynote Address: The Neurophysiology of Functional Neurosurgery Yoichi Katayama 9:00 - 10:35 AM Plenary Session II 8:30 - 8:35 AM Papers (6 papers - 8 minute presentations - 5 minute discussions) Moderators: Jin Woo Chang/Mojgan Hodaie 9:00-9:13: Deep Brain Stimulation for Parkinson Disease - Results of the EARLYSTIM Study ( 190) Maximilian H. Mehdorn 9:45-9:58: Long Term Effects of Deep Brain Stimulation of the Medial Forebrain Bundle (slMFB DBS) for treatment resistant depression (173) Volker A. Coenen 9:15-9:28: Treatment of Memory Decline in Alzheimer’s Disease by Deep Brain Stimulation: A Feasibility Study (71) Denys Fontaine 10:00-10:13: Deep Brain Stimulation of the Subcallosal Cingulate Area for Treatment-Refractory Anorexia Nervosa: Phase I Pilot Trial ( 27) Nir Lipsman 9:30-9:43: Pedunculopontine nucleus-stimulation in patients with Advanced Parkinson’s disease (227) Mohammad J. Nausahi 10:15-10:28: A Randomized Blinded Trial of Nucleus Accumbens Ablation to Treat Opiate Dependence in Humans: Location Correlates with Outcome (270) Guodong Gao 10:35 - 10:50 AM Refreshment Break - View Posters - Meeting Room Foyer 10:50 AM - Noon Papers (5 papers - 8 minute presentations - 5 minute discussions) Moderators: Hiroki Toda/Robert Gross 10:50-11:03: What Happened in the Lobotomized Brain?: Tractographic Analysis of Prefrontal lobotomy for Mental Illness (165) Katsushige Watanabe 11:35-11:48: Nerve Fiber Composition of Posterior Subthalamic Area and Its Relevance for the Treatment of Parkinson’s Disease Symptoms (77) Francisco Velasco 11:05-11:18: Where the Parallels Meet: Evidence of Functional Convergence of Basal Ganglia Circuits in Subthalamic Nucleus From Intra-operative Multichannel-microelectrode Recording (332) Erich T. Fonoff 11:50-12:03: Modulation of Neural Network Excitability with an Implantable Closed-Loop DBS System (321) Paul Stypulkowsi 11:20-11:33: Experimental Comparison in Non-human Primates of Focal Tolerance Between Epidural and Subdural Implantation of a Cortical Neuroprosthesis (276) Napoleon R. Torres-Martinez wssfn Wednesday, May 29, 2013 World Society for Stereotactic and Functional Neurosurgery PEGASUS AB1 PEGASUS C APOLLON Bento Box Debate IV: Dystonia: DBS vs. Lesioning vs. Peripheral Procedures Bento Box Debate V: Tourette’s Syndrome Bento Box Debate VI: Controversies in Psychiatric Neurosurgery Moderators: Elena Moro/Claudio Pollo Moderators: Ashwin Viswanathan/ Zelma Kiss Moderators: Marwan Hariz/ Sally Rothemeyer • GPi: Philippe Cornu • Surgery for Schizophrenia: Bomin Sun • Peripheral is Best: Tommy Bergenheim • Thalamus: Joachim Krauss • Surgery for Aggression: Fabian Piedimonte • GPe: Osvaldo Vilela • Not So Fast: Volker Coenen PEGASUS AB1 PEGASUS C APOLLON Afternoon Session IV: From the Laboratory to the Clinic Afternoon Session V: Surgery for Pain: Only When Nothing Else Works? Afternoon Session VI: Stereotactic Technology 1:30 - 2:00 PM Keynote Address: The Hyperdirect Pathway and Motor Control Atsushi Nambu Keynote Address: Peripheral Nerve Stimulation for Pain Konstantin Slavin Keynote Address: Stereotactic Principles: The Evolution of Image Guidance David Roberts 2:00 - 3:00 PM Papers Papers Papers (5 papers - 7 minute presentations 3 minute discussions) (5 papers - 7 minute presentations 3 minute discussions) (5 papers - 7 minute presentations 3 minute discussions) Moderators: Zvi Israel/Moon Chan Kim Moderators: Juan Barcia/Bengt Linderoth 2:00-2:10: in Vivo Brain Repair? Electrical Fields Attract Newborn Brain Cells (380) Ali Jahanshahi 2:00-2:10: Motor Cortex Stimulation Efficacy in Refractory Neuropathic Pain Might Be Predicted by Brain 11C-diprenorphine Pet-scans (289) Patrick Mertens Moderators: Rick Schuurman/ Masahito Kobayashi Afternoon Sessions Bento Box Debates Noon - 1:30 PM • DBS is Best: Ron Alterman • Lesioning is Best: Takaomi Taira 2:12-2:22: Deep Brain Stimulation of the Cm-pf in Rats Alleviate Breedinginduced Deficient Prepulse Inhibition (202) Mesbah Alam 2:24-2:34: Theta Burst Stimulation of the Hippocampus Via an Electrode Implanted in the Fornix Is Associated With Improved Cognitive Performance After Moderate Traumatic Brain Injury (58) Jonathan Miller 2:36-2:46: Recordings of Local Field Potentials in the Bed Nucleus of the Stria Terminalis in a Rat Model of ObsessiveCompulsive Disorder (317) Hemmings Wu 2:48-2:58: STN -Deep Brain Stimulation in OCD: Preliminary Results of the Grenoble Cohort At 18 Months Follow Up (217) Stephan Chabardes 2:12-2:22: Simultaneous Trial of Deep Brain Stimulation (DBS) and Motor Cortex Stimulation (MCS) for Chronic, Intractable Neuropathic Pain (67) Byung-chui Son 2:24-2:34: Differential Efficacy of Motor Cortex Stimulation and Lesioning of the Dorsal Root Entry Zone for Continuous Vs Paroxysmal Pain Afterroot Avulsion (234) Youichi Saitoh 2:36-2:46: Deep Brain Stimulation in Chronic Cluster Headache (CCH): Lead Location, Clinical Response and Neuronal Signatures (211) Fahid T. Rasul 2:48-2:58: Rechargeable Occipital Nerve Stimulator Systems a Patient Satisfaction Study (144) Sara Sciacca 2:00-2:10: Steering Deep Brain stimulation: an exploratory study with a new 32-contact lead (343) Rick Schuurman 2:12-2:22: Convection Enhanced Delivery: Infusion characteristics in ex vivo and in vivo non-human primate brain tissue (412) Gurwattan S. Miranpuri 2:24-2:34: Accuracy of Electrode Placement, Clinical Response and Complication rate in Frameless Stereotaxis (NexFrame) for Movement disorders (253) Matthew G. Stovell 2:36-2:46: Validating Diffusion Tensor Imaging of the Thalamus with Intraoperative Mircroelectrode Recording (390) Hiroki Toda 2:48-2:58: Techniques for Axiem™ Electro-magnetic Navigation Guided Balloon Compression of Trigeminal Nerve (32) Sarah L. Olson Wednesday, May 29, 2013 3:00 - 3:30 PM Refreshment Break - View Posters & Exhibits - Meeting Room Foyer 3:30 - 4:30 PM PEGASUS AB1 PEGASUS C APOLLON Flash presentations (15 papers, 3 minutes each) Flash presentations (15 papers, 3 minutes each) Flash presentations (15 papers, 3 minutes each) Moderators: Jules Nazzaro/Jorge Guridi Moderators: Brian Brophy/Miroslav Galanda Moderators: M. Sam Eljamel/Wilhelm Eisner 3:30-3:33: Stereotactic Thalamic Vimvcpc Stimulation for the Treatment of Cases with Central Post-stroke Pain (70) Masafumi HIrato 3:30-3:33: Definition of a Stereotactic 3D Model of the Human Insula for Neurosurgical Approach (epilepsy and Stereotaxic Surgery) (140) Afif M. Afif 3:34-3:37: Testing the Opioidergic Hypothesis of PAG-DBS for Pain: A [11c] Diprenorphine PET Imaging Study (48) Hugh P. Sims-Williams 3:34-3:37: Robotics in Neurosurgical Stereotactic Interventions: Oblique Intrainsular Electrodes Implanted of Patients with Epilepsy (183) Afif M. Afif 154 3:38- 3:41: Deep brain stimulation in Short Lasting Unilateral Headache with Conjunctival Injection and Tearing (SUNCT) (181) Sarah Miller 3:38- 3:41: Comparison of Voltage and Current Driven Deep Brain Stimulation (75) Sam Eljamel 3:34-3:37: Influence on Synaptic Plasticity in Corticostriatal Pathway of Parkinson Disease Animal Model (377) Yuan-Hao Chen 3:38-3:41: Autologous Peripheral Nerve Grafts into the SN of Subjects with PD Undergoing DBS (284) Craig G. van Horne 3:42-3:45: Cortical Electric Stimulation in the Treatment Brain Tumors: Induction of Plastic Changes to Obtain Extended Resection in Gliomas (184) Juan Barcia 3:46-3:49: Bilateral Pedunculopontine Nucleus Stimulation for Progressive Supranuclear Palsy (44) Paresh K. Doshi 3:50-3:53: Potential Role of L-PGDS as a Surrogate Marker of Frontal Lobe Dysfuntion (47) Namiko Nishida 3:54-3:57: Subthalamic Nucleus Stimulation Reverses Spinal Motoneurone Activity in Parkinsonian Patients (59) Sylvie Raoul 3:58-4:01: Different Performance Between Food Reaching Motors and Finger Precise Motors Ameliorated by STN-DBS in MPTP-treated Monkeys (118) Tetsuya Asakawa 4:02-4:05: Isolation and Transplantation Protocol of Human Fetal Neural Progenitor Cells in the Treatment of Huntington’s and Parkinson’s Disease (200) William O. Contreras Lopez 4:06-4:09: A Novel Intraoperative Method for Monitoring Hyperacute Changes in Cerebral Ischemia (361) Hiroshi Fujioka 4:10-4:13: Neurophysiological Characteristics of Subthalamic Neurons Receiving Inputs From the Limbic Cortex (376) Sumito Sato 4:14-4:17: Anatomic Study of Fiber Tracts Linking the Basal Ganglia and Cerebellum in Patients with Parkinson’s Disease (49) Jennifer A. Sweet 3:46-3:49: Pulsed Radiofrequency of Sympathetic Lumbar Plexus Versus Sympathetic Block in the Management of Lower Limb Complex Regional Pain Syndrome Type 1 (324) Tiago S. Freitas 3:50-3:53: Intrathecal Ziconotide (ITZ) for the Treatment of Sublesional Neuropathic Pain in Patients With Spinal Cord Lesions (296) Patrick Mertens 3:54-3:57: Open Thoracic Cordotomy for pain: Lost art or a reviving skill? (256) Naeem A. Farooqo 3:58-4:01: Long term Outcomes for the Use of Dorsal root entry zone (DREZ) Lesioning for Brachial Plexus Avulsion Injury (287) Jonathan R. Ellenbogen 4:02-4:05: Motor Cortex Stimulation for the Treatment of Severe Pain (239) Vladimir A. Shabalov 4:06-4:09: Motor Cortex Stimulation for the Treatment of Severe Pain (339) Erich T. Fonoff 4:10-4:13: Combined fMRI, SSER, and Intraoperative Stimulation for Identification of Cortical Areas in Motor Cortex Stimulation for Pain (189) Tommy Bergenheim 3:42-3:45: Early Experience with MRIdirected Implantable Guide Tube Technique for Deep Brain Stimulation (142) Christopher R. P. Lind 3:46-3:49: A Novel Recessed-step Catheter for Reflux-free Convectionenhanced Drug Delivery to the Brain (111) Neil Barua 3:50-3:53: The Yield and Safety of Robotic-assisted Stereotactic Biopsy Versus Frameless Stereotactic Biopsy (364) Tariq Aljared 3:54-3:57: Simultaneous 32-contact Local Field Potential Recordings in the Parkinsonian STN (344) Rick Schuurmann 3:58-4:01: Use of a Novel, Rapidly Generated Custom Platform for Stereotactic DBS Implantation (416) Jason Agran 4:02-4:05: Identification of Blood Vessels With Micro Doppler Ultrasound Songraphy in Stereotactic Functional Neurosurgery Via Microelectrode Guide Tubes - A Prototype of High Value! (221) Wilhelm E. Eisner 4:06-4:09: Supine Position reduces Brain Shift during Stereotactic Neurosurgery (66) Yasushi Miyagi 4:10-4:13: Impact of Parameters of Radiofrequency Coagulation on Volume of Stereotactic Lesion in Pallidotomy and Thalamotomy (213) Hidehiro Hirabayashi 4:14-4:17: Peripheral Field Stimulation for Chronic Focal Pain (369) Milind Deogaonkar 4:14-4:17: Neuronal Activity in the Prefrontal-cortex Is Reduced in Rats Selectively Bred for Disturbed Sensorimotor Gating (205) Mesbah Alam 4:18-4:21: Selective Dorsal Rhizotomy for Neoplastic lumbosacral plexopathy in terminal pelvic cancer (40) Byung-chul Son 4:18-4:21: Diagnostic Yield of 1H-MRSsupported Stereotactic Brain Biopsy: Overview of Published Results (263) Mikhail F. Chernov 4:40 - 5:30 PM Plenary Session 4:18-4:21: Robot-assisted Guide Tube Implantation for Functional Neurosurgery - Analysis of Targeting Accuracy and Procedural Time (116) Neil Barua 3:42-3:45: Implanted Occipital Nerve Stimulation Results for Intractable Headache Predicted by Transcutaneous Electrical Nerve Stimulation (303) Vincent Roualdes Plenary Session: Scientific Highlights and Discussion, Day 2 Moderators: Alon Mogilner/Ahmed Al-Khani Discussants: Travis Tierney/Alexandre Francisco 7:00 - 10:00 PM Gala Reception and Dinner PEGASUS wssfn Thursday, May 30, 2013 World Society for Stereotactic and Functional Neurosurgery Thursday, May 30, 2013 Breakfast in meeting rooms 7:15 - 8:15 AM PEGASUS AB1 PEGASUS C APOLLON Breakfast Seminar VII: Setting International Standards in Functional Neurosurgery: Training, Education and Expansion Breakfast Seminar VIII: Surgery for Enhancement Breakfast Seminar IX: SRS: New Frontiers Moderators: Julie Pilitsis/Guoming Luan Moderators: Masaaki Yamamoto/ Dheerendra Prasad Breakfast Seminars 7:00 AM Moderators: Isao Date/Rick Schuurman • Spectrum of Fellowships in SFN: Gaston Schechtmann • Epilepsy: Eiju Watanabe • Cognition: Emad Eskandar • Ethical Considerations: Mark Bernstein • Setting Up a Program in Functional Neurosurgery: Erich Richter • Fractionation: Roberto Spiegelmann • Microbeam Radiosurgery: Pantaleo Romanelli • Heavy Particles: Takeshi Kondoh 8:30 - 8:35 AM 8:35 - 9:05 AM 9:05 - 10:20 AM Plenary Session III • Do We Need International Fellowship Standards? Mojgan Hodaie PEGASUS AB1 Plenary Session III: New Indications for Functional Neurosurgery Welcome Joachim Krauss Keynote Address: Surgery for Neurobehavioral Disorders Ali Rezai Papers (5 papers - 8 minute presentations - 5 minute discussions) Moderators: Aviva Abosch/Patric Blomstedt 9:05-9:18: Deep Brain Stimulation of the Fornix and Entorhinal Cortex in an Experimental Model of Memory Impairment (379) Ali Jahanshahi 9:50-10:03: In Search of Neurobiological Correlates To Depression: Electrical Stimulation of the Amygdala (137) Kelly R. Bijanki 9:20-9:33: Results of Neuromodulation of the Posterolateral Hypothalamic Region in Cluster Headache. Are We on the Right Place? (90) Fernando Seijo 10:05-10:18: Deep Brain Stimulation Eliminates Tic-related Neural Activity Via Interlocking With Stimulus Pulses (13) Kevin W. McCairn 9:35-9:48: An Exploratory Pilot Study of Intra-Thecal Spinal Cord Stimulation (IT-SCS): Implications for the future management of chronic pain (206) Nandan Lad 10:20 - 10:40 AM 10:40 - 11:40 AM 11:40 - Noon Refreshment Break and View Posters Meeting Room Foyer Papers (4 papers - 8 minute presentations - 5 minute discussions) Moderators: Giovanni Broggi/Steven Gill 10:40-10:53: Augmentation of Perilesional Plasticity by Chronic Stimulation of the Dentatothalamocortical Pathway in an Animal Model (94) Andre Machado 11:10-11:23: Peripheral Nerve Stimulation (PNS) and Peripheral Nerve Field Stimulation (PNFS) for the Treatment of Chronic Neuropathic Pain (244) Emil D. Isagulyan 10:55-11:08: Spinal Cord Stimulation for the Treatment of Minimally Conscious State Patients (29) Takamitsu Yamamoto 11:25-11:38: Improved Intraoperative Therapeutic Window with Directional DBS Compared to Omnidirectional DBS Using a Novel Lead Design (319) Claudio Pollo WSSFN Business Meeting Thursday, May 30, 2013 Bento Box Debates Noon - 1:30 PM PEGASUS AB1 PEGASUS C APOLLON Bento Box Debate VII: New Indications: When to Push the Limits Bento Box Debate VIII: Surgical Treatment of Spasticity (sponsored) Bento Box Debate IX: Hypothalamic Tumors - What Is the Best Treatment? Moderators: Damianos Sakas/Ben Jonker Moderators: Marc Sindou/Karl Sillay Moderators: Mikhail Chernov/Ashwin Viswanathan • DBS for Obesity: Donald Whiting • Intrathecal Infusion: Takaomi Taira • SRS: Jean Regis • Neurotomy: Phillipe Decq • Resection: Jeffrey Rosenfeld • DBS for Tinnitus: Paul Larson • Not So Fast: Roy Bakay 1:30 - 2:00 PM Afternoon Sessions 2:00 - 3:00 PM • Dorsal Rhizotomy: Graham Fieggen • LITT: Taku Ochiai PEGASUS AB1 APOLLON PEGASUS C Afternoon Session VII: Psychiatric Surgery Afternoon Session VIII: Imaging for Functional Neurosurgery Afternoon Session IX: Movement Disorders Keynote Address: Guidelines for Psychiatric Neurosurgery Bart Nuttin Keynote Address: Imaging for Epilepsy Surgery Nobukazu Nakasato Keynote Adress: Ethics of Deep Brain Stimulation Surgery Marwan Hariz Papers (5 papers - 7 minute presentations 3 minute discussions) Papers (5 papers - 7 minute presentations 3 minute discussions) Papers (5 papers - 7 minute presentations 3 minute discussions) Moderators: Rees Cosgrove/ Yoichi Katayama Moderators: Kostantinos Fountas/ Wai Hoe Ng Moderators: Milind Deogaonkar/ Goetz Lutjens 2:00-2:10: Neurosurgery for Psychiatric Disorders in the People’s Republic of China- Responsibilities of International Societies (293) Hemmings C. Wu 2:00-2:10: Exploring the Anatomical Connectivity of the Human Pedunculopontine Nucleus With Structural and Diffusion-tensor MRI (8) Yasir Chowdhury 2:00-2:10: Deep Brain Stimulation of the Dentato-rubro-thalamic Tract (drt) for the Treatment of Therapy Refractory Tremor (171) Volker A. Coenen 2:12-2:22: Long-term Follow-up of Deep Brain Stimulation for Refractory Obsessive-compulsive Disorder (160) Young Cheol Na 2:12-2:22: White Matter Tracts Deep To Cg25: What Are We Targeting? (373) Kartik D. Bhatia 2:24-2:34: Deep Brain Stimulation for Severe Treatment-resistant Depression (26) Rodrigo Rodriguez 2:24-2:34: Early Experience of Pre- and Post-contrast 7.0T MRI in Brain Tumors (267) Jae Ha Hwang 2:36-2:46: DBS in Tourette Syndrome: Lessons Learnt After 8 Years (286) Domenico Servello 2:36-2:46: Localization of DBS Targets by Deterministic Tractography: A Straightforward Method with Plausible Results (224) Josue Avecillas 2:48-2:58: The Vancouver Experience with Neurosurgery for Depression: Lesions versus DBS (325) Chris Honey 2:12-2:22: Zona Incerta as a Target for DBS - The Umeå Experience of 100 Patients (87) Patric Blomstedt 2:24-2:34: Anatomo-clinical Correlations of Deep Brain Stimulation (DBS) of the Pedunculopontine Nucleus Area (PPNa) At 12 Months Follow Up (280) Laurent Goetz 2:36-2:46: Beta Oscillatory Activity of Single Neurons in the Subthalamic Nucleus in Patients With Parkinson’s Disease (95) Kazutaka Kobayashi Refreshment Break - View Posters & Exhibits - Meeting Room Foyer 3:00 - 3:30 PM Afternoon Session VII: WSSFN 2016: Predictions PEGASUS AB1 Keynote Address: Looking Back and Ahead in Functional Neurosurgery - Where We Came From, and Where Are We Heading Alim Benabid 3:30 - 4:00 PM 4:00 - 5:00 PM 5:00 - 5:30 PM Papers (4 papers - 8 minute presentations - 5 minute discussions) Moderators: Volker Sturm/Takeshi Kawase 4:00- 4:13: Anatomo-radiologic Correlation To Achieve Maximum Accuracy in Leads Implantation for Chronic Stimulation of Sphenopalatine Ganglion (215) Fabian C. Piedimonte 4:30- 4:43: Localisation of the Subthalamic Nucleus in Parkinson’s Disease with Neural Beta and Gamma Activity of Local Field Potentials (345) Rick Schuurmann 4:15-4:28: Deep Brain Stimulation Induces Changes in Cerebral Perfusion in Patients With Tourett e Syndrome (210) Goetz Lutjens 4:45- 4:58: Deep Brain Stimulation for the Early Treatment of the Minimal Coscious Sate and Vegetative State (201) Darko Chudy Closing Ceremony Resident Awards wssfn WSSFN Sponsor and Exhibitor Information SAKURA LEVEL SAKURA LEVEL At Medtronic, we’re committed to Innovating for life by pushing the boundaries of medical technology and changing the way the world treats chronic disease. Last fiscal year, more than eight million patients benefited from our products and therapies. Medtronic DBS Therapy has been used in more than 100,000 patients worldwide for the treatment of Parkinson’s disease, essential tremor and dystonia. World Society for Stereotactic and Functional Neurosurgery MATSU LEVEL Elekta is a human care company pioneering significant innovations and clinical solutions for treating cancer and brain disorders. The company develops sophisti‑ cated, state-of-the-art tools and treatment planning systems for radiation therapy, radiosurgery and brachytherapy, as well as workflow enhancing software systems across the spectrum of cancer care. Stretching the boundaries of science and tech‑ nology, providing intelligent and resource-efficient solutions that offer confidence to both healthcare providers and patients, Elekta aims to improve, prolong and even save patient lives. Today, Elekta solutions in oncology and neurosurgery are used in over 6,000 hospi‑ tals worldwide. Elekta employs around 3,400 employees globally and the corporate headquarters is located in Stockholm, Sweden. Website: www.elekta.com. Ta’ke Level Investing in innovative products, clinical initiatives, and world-class service, Boston Scientific is committed to leading the way in spinal cord stimulation by providing better pain relief to a broad range of patients. www.controlyourpain.com Founded in 1999, InSightec Ltd. is a privately held innovative medical device company that has developed the breakthrough MR guided Focused Ultrasound (MRgFUS) technology and transformed it into a next generation operating room. Headquartered in Israel, the company has invested in research, development, and clinical investigations of its ExAblate system to thermally ablate tumors inside the body – incision-less, with real-time anatomic and thermal feedback. ExAblate is currently used to treat uterine fibroids as well as for pain palliation of bone metastases. ExAblate Neuro has been developed for transcranial, functional stereotactic applications and has received CE mark for treating essential tremor, tremor dominant Parkinson’s disease and neuropathic pain. Other applications of focused ultrasound neurosurgery are under clinical investigation. More information at www.InSightec.com Ume Level Committed to Advancing Neural microTargeting Worldwide For over 40 years FHC has served the neuroscience community with a commitment to innovate through collaboration. Come see our new Cable Management System and our improved STarFix™ Platform for patient-specific stereotaxy. Demo our WayPoint™ Navigator Planning System, the Guideline 4000 LP+™ Recording/Stimulating System and STar™ Microdrive Systems. All backed with 24x7 technical support. Renishaw is applying cutting-edge precision engineering technology to the chal‑ lenges of functional neurosurgery. We are helping leading clinicians to enhance the safety and cost-effectiveness of their procedures, improving patient outcomes through consistently accurate delivery of implantable devices. The neuromate ® stereotactic robot provides a platform solution for a broad range of functional neurosurgical procedures. neuromate has been used in thousands of electrode implantation procedures for Deep Brain Stimulation (DBS), Stereotactic Electroencephalography (SEEG), neuroendoscopy, biopsy, as well as R&D applications in radiosurgery, drug delivery and Transcranial Magnetic Stimulation. ® St. Jude Medical develops medical technology and services that focus on putting more control into the hands of those who treat cardiac, neurological and chronic pain patients worldwide. SJM has provided leading neurostimulation therapy innovations for 30 years. The company is dedicated to advancing the practice of medicine by reducing risk wherever possible and contributing to successful outcomes for every patient. Innsbruck-based MED-EL Medical Electronics is a leading provider of hearing implant systems worldwide. The family-owned business is one of the pioneers in the industry. The two Austrian scientists Ingeborg and Erwin Hochmair developed the world’s first microelectronic-multichannel Cochlear-Implant in 1977. The cochlear implant was and remains the first replacement of a human sense, the sense of hearing. In 1990 they laid the foundation for the successful growth of the company when they hired their first employees. To date, the company has grown to more than 1400 employees around the world. Today MED-EL offers the widest range of implantable solutions worldwide to treat various degrees of hearing loss: cochlear and middle ear implant systems, EAS (combined Electric Acoustic Stimulation) hearing implant system and auditory brainstem implants as well as the world’s first active bone conduction implant. People in about 100 countries enjoy the gift of hearing with the help of a product from MED-EL. www.medel.com Yanagi Level Alpha Omega has been known in the industry for more than two decades, as a global leader in the fields of Functional Neurosurgery and Neuroscience Research, offering its clients breakthrough technology, unrivalled dependability, and dedi‑ cated service. For Functional Neurosurgery, Alpha Omega offers Microelectrode recording (MER) equipment for Deep Brain Stimulation (DBS) procedures along with powerful research capabilities. For Neuroscience Research, Alpha Omega offers variety of powerful electrical and mechanical solutions in the field of In-Vivo extracellular recording, allowing neuro‑ scientists to discover brain signals even in the resolution of a single cell activity. Cyberonics, Inc. is the leader in device solutions for epilepsy and is committed to consistently delivering innovative and effective solutions for physicians, caregivers and people with epilepsy. Cyberonics’ VNS Therapy ® is the only FDA-approved device for the treatment of refractory epilepsy, with more than 70,000 patients implanted worldwide. WSSFN Quadrennial Meeting 2013 Yanagi Level Brainlab develops, manufactures and markets software-driven medical technology, enabling access to improved, more efficient, less-invasive patient treatments. Core products revolve around less-invasive image guided surgery technology, more accurate and effective radiation therapy, and integration through planning and collaboration systems that bring patient data and physicians together. Brainlab technology currently powers treatments in the fields of neurosurgery, radiation oncology, orthopedics, ENT, CMF, spine, trauma and radiology. Privately held since its formation in Munich, Germany in 1989, Brainlab has more than 5,000 systems installed in about 80 countries. Brainlab employs 1,120 people in 17 offices worldwide, including 290 Research & Development engineers, who form a crucial part of the product development team. Recognizing ADDITIONAL COMPANIES for their Contribution Daiichi Sankyo is a global pharmaceutical company with corporate origins in Japan. We provide innovative products and services in more than 50 countries around the world. With more than 100 years of scientific expertise, our company draws upon a rich legacy of innovation and a robust pipeline of promising new medicines to help patients. Through the accumulated knowledge and commitment of our 30,000 employees worldwide, we create innovative new and generic medicines, and new methods of drug discovery and delivery. We share a passion for innovation, as well as compassion for the patients around the world who are in need of our medicines. Toshiba Medical Systems Corporation Toshiba Medical Systems Corporation is a leading worldwide provider of medical diagnostic imaging systems and comprehensive medical solutions, such as CT, X-ray and vascular, ultrasound, nuclear medicine, and MRI systems, as well as information systems for medical institutions. Toshiba Medical Systems Corporation has been providing medical products for over 80 years. Toshiba Medical Systems Corporation is a wholly-owned subsidiary of Toshiba. Visit Toshiba Medical Systems Corporation’s web site at http://www.toshibamedicalsystems.com For over 80 years, Ethicon has been at the forefront of innovation to advance the practice of surgery. Starting as a surgical suture company, we’ve grown in response to the needs of health care practitioners whose life’s work it is to safely and effectively meet the needs of patients the world over. Thank you to the following companies for their generosity in providing educational grants in support of this activity: Alpha Omega BrainLab Cyberonics Elekta FHC Insightec Integra Life Med-El Medtronic Renishaw St. Jude Medical A sincere thank you to the following exhibitors: Alpha Omega Boston Scientific BrainLab Cyberonics Daiichi-Sankyo Elekta Ethicon FHC Insightec Karger Med-El Medtronic NANS Renishaw St. Jude Medical Toshiba Medical Systems Visualase Integra LifeSciences, a world leader in medical devices, is dedicated to limiting uncertainty for surgeons, so they can concentrate on providing the best patient care. Integra offers a vast portfolio of implants, devices, instruments and systems used in neurosurgery and neuro critical care. KARGER is a leading international publisher of books and journals in basic and medical sciences. During the WSSFN Congress in Tokyo we are pleased to present a wide range of publications in neurosurgery. Our journal Stereotactic and Functional Neurosurgery is the official organ of the WSSFN, ASSFN and ESSFN. Free sample copies are available at our booth. Be sure not to miss the latest publications of our book series Progress in Neurological Surgery. All publications are accessible online at www.karger.com/neurosurgery, with full-text search of articles and many other services. The Visualase Thermal Therapy System is an MRI-guided, minimally invasive laser ablation system which allows for monitoring of an ablation in real-time with screen updates every 4-5 seconds. The system is FDAcleared for the ablation of soft tissue including for use in neurosurgical procedures (see www.visualaseinc.com for complete indication). More than 20 US centers have now performed >150 epileptogenic foci and >150 brain tumor ablation procedures. The North American Neuromodulation Society (NANS) is dedicated to being the premier organization representing neuromodulation. NANS promotes multidisciplinary collaboration among clinicians, scientists, engineers, and others to advance neuromodulation through education, research, innovation and advocacy. Through these efforts NANS seeks to promote and advance the highest quality patient care. WSSFN Travel Awards This year, the World Society is pleased to offer a large number of travel grants to residents and fellows participating in the quadrennial meeting in Tokyo. These grants, based on scientific merit and geographical location, have been made available to facilitate attendance to the meeting and are a direct reflection of the society’s mandate of nurturing the field stereotactic and functional neurosurgery across the globe. The society wishes to recognize and encourage strong scientific contributions to the field internationally, while promoting the field of stereotactic and functional neurosurgery in areas where it is not easily available. We are encouraged by the strong participation and interest during the WSSFN interim meeting of the society in South Africa, 2011. As a result, a number of travel awards have been made available to participants from Africa. We are confident of the fruitful outcome that accompanies increasing international participation and collaboration. I would like to acknowledge the invaluable contributions of Dr. Joseph Neimat, Vanderbilt University, and Dr. Graham Fieggen, University of Cape Town, in the selection process of the awardees. The travel grant awardees of the 16th quadrennial meeting of the WSSFN are as follows: Jason Agran - United States Mawuli Ametefe - Ghana Pedro de la Rosa - Spain Anna Gamalya - Russia David Kis - Hungary Nan Li - China C.C. Liao - Taiwan Ouerchefani Naoufel - Tunisia Naomi Ochieng’ - Kenya Taopheeq Rabiu - Nigeria Fahid Rasul - United Kingdom Jie Ren - China Anand Rughani - Canada Samuila Sanoussi - Niger Demitre Serletis - United States Krzysiek Szalecki - Poland Hemmings Wu - Belgium It has been a pleasure to participate in the selection of the travel awards and we welcome you all to Tokyo! Mojgan Hodaie Scientific Program co-Chair and Travel Awards Coordinator