Publications on the use of MicroSys (1999 – July 2016) 2016 Screening of Pre-miRNA-155 Binding Peptides for Apoptosis Inducing Activity Using Peptide Microarrays. Jaeyoung Pai, Soonsil Hyun, Ji Young Hyun, Seong-Hyun Park, Won-Je Kim, Sung-Hun Bae, NakKyoon Kim, Jaehoon Yu, and Injae Shin. Journal of the American Chemical Society, 27 January 2016; 138(3): 857-867. (MicroSys 5100) Enzymatic and Structural Characterization of the Major Endopeptidase in the Venus Flytrap Digestion Fluid. Michael W. Risør, Line R. Thomsen, Kristian W. Sanggaard, Tania A. Nielsen, Ida B. Thøgersen, Marie V. Lukassen, Litten Rossen, Irene Garcia-Ferrer, Tibisay Guevara, Carsten Scavenius, Ernst Meinjohanns, F. Xavier Gomis-Rüth and Jan J. Enghild Journal of Biological Chemistry, 29 January 2016; 291(5): 2271-2287. Carbohydrate microarrays for screening functional glycans. Jaeyoung Pai, Ji Young Hyun, Jieun Jeong, Sohee Loh, Eun-Hee Cho, Young-Sun Kang, Injae Shin. Chemical Science, 1 March 2016; 7(3): 2084-2093. (MicroSys 5100) http://pubs.rsc.org/en/content/articlepdf/2016/sc/c5sc03789a?page=search Development of Novel Technologies for Direct Cellular Patterning for the Establishment of Well Controlled Microenvironments to Facilitate Studies on Cellular Signaling, Sensing, and Other Diffusion-Based Phenomena William Hynes PhD Theses, 7 May 2016; SUNY Polytechnic Institute, 133 pp (MicroSys 5100 4SQ) https://dspace.sunyconnect.suny.edu/bitstream/handle/1951/66926/HynesDissertation.pdf?sequence=1&isAllowed=y Hybrid microarray based on double biomolecular markers of DNA and carbohydrate for simultaneous genotypic and phenotypic detection of cholera toxin-producing Vibrio cholerae. Hwa Hui Shin, Jeong Hyun Seo, Chang Sup Kim, Byeong Hee Hwang, and Hyung Joon Cha. Biosensors and Bioelectronics, 15 May 2016; 79: 398-405. (MicroSys 5100) Structure of the I-SceI nuclease complexed with its dsDNA target and three catalytic metal ions. Jesús Prieto, Pilar Redondo, Nekane Merino, Maider Villate, Guillermo Montoya, Francisco J. Blanco, and Rafael Molina. Acta Crystallographica Section F: Structural Biology Communications, 1 June 2016; 72(6): 473-479. https://www.researchgate.net/profile/Rafael_Molina4/publication/303502251_Structure_of_the_ISceI_nuclease_complexed_with_its_dsDNA_target_and_three_catalytic_metal_ions/links/5746f6ad0 8ae9f741b452a11.pdf Structural mimicry of receptor interaction by antagonistic IL-6 antibodies. Christophe Blanchetot, Natalie De Jonge, Aline Desmyter, Nico Ongenae, Erik Hofman, Alex Klarenbeek, Ava Sadi, Anna Hultberg, Anke Kretz-Rommel, Silvia Spinelli, Remy Loris, Christian Cambillau and Hans de Haard Journal of Biological Chemistry, 24 June 2016; 291(26): 13846-13854 (MicroSys SQ) http://www.jbc.org/content/291/26/13846.full.pdf 2015 A novel mechanism of latency in matrix metalloproteinases. Mar López-Pelegrín, Miroslaw Ksiazek, Abdulkarim Y. Karim, Tibisay Guevara, Joan L. Arolas, Jan Potempa & F. Xavier Gomis-Rüth Journal of Biological Chemistry, 2 January 2015; jbc-M114.605956 http://www.jbc.org/content/early/2015/01/02/jbc.M114.605956.full.pdf+html Method of making a hydrogel. Inventors: Catherine Louise Ruby Merry, Alberto Saiani, Kate Alexandra Meade, Emma Tranquility Lowe, Aline Fiona Saiani, and Jean-Baptiste Guilbaud. U.S. Patent Application: 2015/0030681 A1, Publication Date: 29 January 2015 (MicroSys 5100 4SQ) https://www.google.com/patents/US20150030681 A novel mechanism of latency in matrix metalloproteinases. Mar López-Pelegrín, Miroslaw Ksiazek, Abdulkarim Y. Karim, Tibisay Guevara, Joan L. Arolas, Jan Potempa, and F. Xavier Gomis-Rüth. Journal of Biological Chemistry, 20 February 2015; 290(8): 4728-4740. (MicroSys 4000XL) http://www.jbc.org/content/290/8/4728.full Development of a high-throughput screen for the identification of novel antifungal drug candidates. Inventors: Anand K. Ramasubramanian, Jose L. Lopez-Ribot, Anand Srinivasan, and Priya Uppuluri. United States Patent: US 8962531 B2, Publication Date: 24 February 2015. https://www.google.com/patents/US8962531 Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses. Chun-Wan Yen, Helena de Puig, Justina O. Tam, José Gómez-Márquez, Irene Bosch, Kimberly Hamad-Schifferli, and Lee Gehrke. Lab on a Chip, 7 April 2015; 15(7): 1638-1641. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375736/ IL-6 binding molecules. Inventors: Christophe Blanchetot, Johannes De Haard, Torsten Dreier, Natalie De Jonge, Woning Paul Sebastian Van Der, and Nicolas Ongenae. U.S. Patent Application: 2015/0140011 A1, Publication Date: 21 May 2015; (MicroSys SQ) http://www.freepatentsonline.com/y2015/0140011.html Validation of a Combinatorial Approach Toward the Discovery of Electrolyte Formulations for Lithium-Ion Batteries Zhange Feng, Charles A. Cartier, and Daniel Scherson. In: The Electrochemical Society, Meeting Abstracts, 26 May 2015; 2: 413. http://ma.ecsdl.org/content/MA2015-01/2/413.short A C-type lectin isolated from the skin of Japanese bullhead shark (Heterodontus japonicus) binds a remarkably broad range of sugars and induces blood coagulation. Shigeyuki Tsutsui, Yuma Dotsuta, Ayaka Ono, Masanari Suzuki, Hiroaki Tateno, Jun Hirabayashi, and Osamu Nakamura. Journal of Biochemistry, May 2015; 157(5): 345-356. (MicroSys4000) Microbial testing devices, methods of making microbial testing devices and methods of identifying novel antimicrobial drug candidates. Inventors: Anand K. Ramasubramanian, Jose L. Lopez-Ribot, and Anand Srinivasan. U.S. Patent Application: 2015/0167046 A1, Publication Date: 18 June 2015; https://www.google.com/patents/US20150167046 Thermal Reaction Device and Method for Using the Same. Inventors: Marc A. Unger, Lincoln McBride, and Geoffrey Facer. U.S. Patent Application: 20150174575 A1, Publication Date: 25 June 2015; (MicroSys5100) https://www.google.com/patents/US20150174575 Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase. Theodoros Goulas, Danuta Mizgalska, Irene Garcia-Ferrer, Tomasz Kantyka, Tibisay Guevara, Borys Szmigielski, Aneta Sroka, Claudia Millán, Isabel Usón, Florian Veillard, Barbara Potempa, Piotr Mydel, Maria Solà, Jan Potempa & F. Xavier Gomis-Rüth Scientific Reports, 1 July 2015; 5: 11969, 17 pp. (MicroSys4000XL) http://www.nature.com/articles/srep11969?WT.ec_id=SREP-63120150707&spMailingID=49041640&spUserID=ODkwMTM2NjQzMAS2&spJobID=720800260&s pReportId=NzIwODAwMjYwS0 A Combinatorial Approach toward the Discovery of Electrolyte Formulations for Non-Aqueous Electrochemical Energy Storage Devices. Charles Cartier, Zhange Feng, Jim Faulk, and Daniel Scherson. ECS Electrochemistry Letters, 16 July 2015; 4(9): A110-A114. http://eel.ecsdl.org/content/4/9/A110.full.pdf+html Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform. Alex Klarenbeek, Khalil El Mazouari, Aline Desmyter, Christophe Blanchetot, Anna Hultberg, Natalie de Jonge, Rob C. Roovers, Christian Cambillau, Sylvia Spinelli, Jurgen Del-Favero, Theo Verrips, Hans J de Haard, and Ikbel Achour MAbs, July-August 2015; 7(4): 693-706. (MicroSys SQ) http://europepmc.org/articles/pmc4622956 Crystal structure of human platelet phosphofructokinase-1 locked in an activated conformation. Marco Kloos, Antje Brüser, Jürgen Kirchberger, Torsten Schöneberg, and Norbert Sträter. Biochemical Journal, 1 August 2015; 469(3): 421-432. Microfluidic assay devices and methods. Inventors: Hany Ramez Nassef, Hou-Pu Chou, Michael Lucero, Andrew May, and Kathy Yokobata. United States Patent: US 9103825 B2, Publication Date: 11 August 2015. (MicroSys 5100) https://www.google.com/patents/US9103825 Crystal structure of insulin-regulated aminopeptidase with bound substrate analogue provides insight on antigenic epitope precursor recognition and processing. Anastasia Mpakali, Emmanuel Saridakis, Karl Harlos, Yuguang Zhao, Athanasios Papakyriakou, Paraskevi Kokkala, Dimitris Georgiadis, and Efstratios Stratikos. The Journal of Immunology, 15 September 2015; 195(6): 2842-2851. (MicroSys4000) A Combinatorial Approach toward the Discovery of Electrolyte Formulations for Non-Aqueous Electrochemical Energy Storage Devices. Charles Cartier, Zhange Feng, Jim Faulk, and Daniel Scherson. ECS Electrochemistry Letters, September 2015; 4(9): A110-A114. http://eel.ecsdl.org/content/4/9/A110.full Structure and binding properties of a cameloid nanobody raised against KDM5B. Anders Wiuf, Line Hyltoft Kristensen, Ole Kristensen, Jerzy Dorosz, J. Jensen, and M. Gajhede. Acta Crystallographica, F: Structural Biology Communications, 1 October 2015; 71(10): 1235-1241. Structure of RagB, a major immunodominant outer-membrane surface receptor antigen of Porphyromonas gingivalis. T. Goulas, I. Garcia-Ferrer, J. A. Hutcherson, B. A. Potempa, J. Potempa, D. A. Scott, and F. Xavier Gomis-Rüth. Molecular Oral Microbiology, 6 October 2015; published ahead of print (MicroSys 4000XL) Structure and binding properties of a cameloid nanobody raised against KDM5B. Anders Wiuf, Line Hyltoft Kristensen, Ole Kristensen, Jerzy Dorosz, Jonas Jensen, and Michael Gajhede. Acta Crystallographica Sec. F: Structural Biology Commns, October 2015; 71(10): 1235-1241. Biomolecule interaction using atomic force microscope. Inventors: Joon Won Park, Yu Jin Jung, Bong Jin Hong, Saul Tendler, and Stephanie Allen. United States Patent: US 9175335 B2, Publication Date: 3 November 2015; (MicroSys 5100) https://www.google.com/patents/US9175335 Mechanisms of proteolytic activity regulation exerted via a unique propeptide in matrix metalloproteinases and intra/intermolecular interactions in a novel family of minimal gluzincins. Maria del Mar López Pelegrín PhD Theses, 13 November 2015; Universitat de Barcelona, 171 pp. (MicroSys 4000XL) http://www.tdx.cesca.cat/handle/10803/347212 Size-controlled macromolecule. Inventors: Joon Won Park, Bong Jin Hong, Young Seo Choi, Soon Jin Oh, and Kwan Yong Choi. United States Patent: US 9201067 B2, Publication Date: 1 December 2015 (MicroSys 5100). https://www.google.com/patents/US9201067 Structure of RagB, a major immunodominant outer-membrane surface receptor antigen of Porphyromonas gingivalis. Theodoros Goulas, Irene Garcia Ferrer, Justin A. Hutcherson, Barbara A. Potempa, Jan Potempa, David A. Scott, and F. Xavier Gomis-Rüth. Molecular oral Microbiology, 2015; ahead of print. (MicroSys 4000XL) A Hard Pill to Swallow: Viable Regulation of 3-D Printed Pharmaceuticals Victoria R. Graf Albany Law Journal of Science and Technology, 2015; 25: 593. 2014 Expression, purification, crystallization and preliminary X-ray diffraction analysis of the novel modular DNA-binding protein BurrH in its apo form and in complex with its target DNA. Stefano Stella, Rafael Molina, Claudia Bertonatti, Alexandre Juillerrat, and Guillermo Montoya. Acta Crystallographica Section F: Structural Biology Communications, January 2014; 70(1): 87-91. http://journals.iucr.org/f/issues/2014/01/00/bo5131/index.html Polynucleotide synthesis on a modified surface. Inventors: Joon-Won Park, and Bong-Jin Hong. United States Patent: US 8647823 B2, Publication Date: 11 February 2014; (MicroSys 5100) https://www.google.com/patents/US8647823 Drug susceptibility of matrix-encapsulated Candida albicans nano-biofilms. Anand Srinivasan, Celia Macias Gupta, C. Agrawal, Kai P. Leung, Jose L. Lopez-Ribot, and Anand K. Ramasubramanian. Biotechnology and Bioengineering, February 2014; 111(2): 418-424 http://www.researchgate.net/profile/Anand_Ramasubramanian/publication/257648438_Drug_suscept ibility_of_matrix-encapsulated_Candida_albicans_nanobiofilms/links/02e7e537288cdc95eb000000.pdf Crystallization and preliminary X-ray diffraction analysis of the homing endonuclease I-CvuI from Chlorella vulgaris in complex with its target DNA. Pilar Redondo, Nekane Merino, Maider Villate, Francisco J. Blanco, Guillermo Montoya, and Rafael Molina. Acta Crystallographica Sect. F: Structural Biology Communications, February 2014; 70(2): 256-259. http://www.researchgate.net/profile/Rafael_Molina4/publication/259752645_Crystallization_and_pre liminary_X-ray_diffraction_analysis_on_the_homing_endonuclease_of_Chlorella_vulgaris_ICvuI_in_complex_with_its_target_DNA/links/0f31752ea2ecf01d73000000.pdf Printing and encapsulation of electrical conductors on polylactic acid (PLA) for sensing applications. Andres Vasquez Quintero, Nathalie Frolet, Daniel Marki, Alexis Marette, Giorgio Mattana, Danick Briand, and Nico F. de Rooij. In: Micro Electro Mechanical Systems (MEMS), 2014 IEEE 27th International Conference, February 2014; pp. 532-535. Biomolecule interaction using atomic force microscope. Inventors: Joon Won Park, Yu Jin Jung, Bong Jin Hong, Saul Tendler, and Stephanie Allen. United States Patent: US 8673621 B2, Publication Date: 18 March 2014; (MicroSys 5100) https://www.google.com/patents/US8673621 A Rapid, Direct, Quantitative, and Label-Free Detector of Cardiac Biomarker Troponin T Using Near-Infrared Fluorescent Single-Walled Carbon Nanotube Sensors. Jingqing Zhang, Sebastian Kruss, Andrew J. Hilmer, Steven Shimizu, Zeke Schmois, Flor De La Cruz, Paul W. Barone, Nigel F. Reuel, Daniel A. Heller, and Michael S. Strano. Advanced Healthcare Materials, March 2014; 3(3): 412-423 Purification, crystallization and preliminary X-ray diffraction analysis of the kinase domain of human tousled-like kinase 2. Ana M. Garrote, Pilar Redondo, Guillermo Montoya, and Inés G. Munoz. Acta Crystallographica Section F: Structural Biology Communications, March 2014; 70(3): 354-357. http://journals.iucr.org/f/issues/2014/03/00/rl5059/index.html Crystallization and preliminary crystallographic analysis of human muscle phosphofructokinase, the main regulator of glycolysis. Marco Kloos, A. Bruser, Juergen Kirchberger, T. Schoneberg, and N. Strater. Acta Crystallographica Section F: Structural Biology Communications, May 2014; 70(5): 578-582. Purification, crystallization and preliminary X-ray diffraction analysis of GatD, a glutamine amidotransferase-like protein from Staphylococcus aureus peptidoglycan. Diana Vieira, Teresa A. Figueiredo, Anil Verma, Rita G. Sobral, Ana M. Ludovice, Herminia de Lencastre, and Jose Trincao. Acta Crystallographica Section F: Structural Biology Communications, May 2014; 70(5): 632-635 Structure of the epimerization domain of tyrocidine synthetase A. Stefan A. Samel, Paul Czodrowski, and L-O. Essen. Acta Crystallographica Section D: Biological Crystallography, May 2014; 70(5): 1442-1452. (MicroSys 4004) The crystal structure of a Cardiovirus RNA-dependent RNA polymerase reveals an unusual conformation of the polymerase active site. Laia Vives-Adrian, Celia Lujan, Baldo Oliva, Lonneke van der Linden, Barbara Selisko, Bruno Coutard, Bruno Canard, Frank JM van Kuppeveld, Cristina Ferrer-Orta, and Núria Verdaguer. Journal of Virology, May 2014; 88(10): 5595-5607. (MicroSys 4000 XL) http://jvi.asm.org/content/88/10/5595.full Microfluidic Devices And Methods Of Using Same Inventors: Lincoln Mcbride, Michael Lucero, Marc Unger, Hany Ramez Nassef, Geoffrey Facer European Patent: EP 1 615 721 B1, Publication Date: 18 June 2014; (MicroSys 5100) http://www.google.com/patents/EP1615721B1?cl=deFl Expression and purification of integral membrane metallopeptidase HtpX. Joan L. Arolas, Raquel García-Castellanos, Theodoros Goulas, Yoshinori Akiyama, and F. Xavier Gomis-Rüth. Protein Expression and Purification, July 2014; 99: 113-118. (MicroSys 4000 XL) http://digital.csic.es/bitstream/10261/101844/1/Arolas_PEP_2014_corrMs.pdf Lectin-Microarray Technique for Glycomic Profiling of Fungal Cell Surfaces. Azusa Shibazaki, and Tohru Gonoi. Methods in Molecular Biology, July 2014; 1200 (Lectins): 287-294. (MicroSys 4000) Directed Evolution of Lectins by an Improved Error-Prone PCR and Ribosome Display Method. Dan Hu, Hiroaki Tateno, and Jun Hirabayashi. Methods in Molecular Biology, July 2014; 1200 (Lectins): 527-538. (MicroSys 4000) Multiple stable conformations account for reversible concentration-dependent oligomerization and autoinhibition of a metamorphic metallopeptidase Mar López-Pelegrín, Núria Cerdà-Costa, Anna Cintas-Pedrola, Fátima Herranz-Trillo, Pau Bernadó, Juan R. Peinado, Joan L. Arolas, and F. Xavier Gomis-Rüth Angewandte Chemie Int Ed Engl., 26 September 2014; 53(40): 10624-10630 (MicroSys 4000XL) http://digital.csic.es/bitstream/10261/124304/4/LopezPelegrin_ACIE_manus%2Bsuppl_rev3.pdf Structure and Mechanism of Cysteine Peptidase Gingipain K (Kgp), a Major Virulence Factor of Porphyromonas gingivalis in Periodontitis. Iñaki de Diego, Florian Veillard, Maryta N. Sztukowska, Tibisay Guevara, Barbara Potempa, Anja Pomowski, James A. Huntington, Jan Potempa, and F. Xavier Gomis-Rüth. Journal of Biological Chemistry, 29 September 2014; 289(46): 32291-32302. (MicroSys 4000 XL) Biomolecule Interaction Using Atomic Force Microscope. Inventors: Joon Won Park, Yu Jin Jung, Bong Jin Hong, Saul Tendler, and Stephanie Allen. US Patent Application: 2014/0315319 A1, Publication Date: 23 October 2014. (MicroSys 5100) http://www.freepatentsonline.com/y2014/0315319.html A C-type lectin isolated from the skin of Japanese bullhead shark (Heterodontus japonicus) binds a remarkably broad range of sugars and induces blood coagulation. Shigeyuki Tsutsui, Yuma Dotsuta, Ayaka Ono, Masanari Suzuki, Hiroaki Tateno, Jun Hirabayashi, and Osamu Nakamura. Journal of Biochemistry, 29 November 2014; 10-1093/jb/mvu080. (MicroSys 4000) 2013 Microfluidic device and methods of using same. Inventors: Marc A. Unger, Ian David Manger, Michael Lucero, Yong Yi, Emily Miyashita-Lin, Anja Wienecke, Geoffrey Facer European Patent: EP1463796 B1, Publication Date: 9 January 2013 http://www.freepatentsonline.com/EP1463796.html Size-controlled macromolecule. Inventors: Joon Won Park, Bong Jin Hong, Young Seo Choi, Soon Jin Oh, Kwan Yong Choi European Patent: EP1664341 B1, Publication Date: 30 January 2013 http://www.freepatentsonline.com/EP1664341.html Non-fouling polymeric surface modification and signal amplification method for biomolecular detection. Inventor: Ashutosh Chilkoti United States Patent: US 8367314 B2, Publication Date: 5 February 5 2013; (MicroSys 5100) https://www.google.com/patents/US8367314 Development of a high-throughput screen for the identification of novel antifungal drug candidates Inventors: Anand K. Ramasubramanian, Jose L. Lopez-Ribot, Anand Srinivasan, Priya Uppuluri, US Patent Application: 20130040854 A1, Publication Date: 14 February 2013 http://www.freepatentsonline.com/y2013/0040854.html Crystallization and preliminary X-ray analysis of membrane-bound pyrophosphatases. Juho Kellosalo, Tommi Kajander, Riina Honkanen, and Adrian Goldman. Molecular Membrane Biology, February 2013; 30(1): 64-74. Structural analysis of coniferyl alcohol 9-O-methyltransferase from Linum nodiflorum reveals a novel active-site environment. Stefan Wolters, Manuel Neeb, Anna Berim, J. Schulze Wischeler, M. Petersen, and A. Heine. Acta Crystallographica Sec D: Biol. Crystallogr., May 2013; 69(5): 888-900. (MicroSys SQ 4000) Biochemical characterization of the Nup62·58·54 nucleoporin complex and mutational analysis of the exportin CRM1. Hema Chug PhD Theses, September 2013; Georg August University Göttingen, 119 pp. https://ediss.uni-goettingen.de/bitstream/handle/11858/00-1735-0000-0023-99060/Hema%20Thesis%20Revised%20110914.pdf?sequence=1 Identification, characterization and preliminary X-ray diffraction analysis of the rolling-circle replication initiator protein from plasmid pSTK1. Stephen B. Carr, Lauren B. Mecia, Simon EV Phillips, and Christopher D. Thomas. Acta Crystallographica, Sect F: Struct Biol Cryst Communs, 1 October 2013; 69(10): 1123-1126. http://journals.iucr.org/f/issues/2013/10/00/rl5044/index.html A piezoelectric micropump with an integrated sensor based on space-division multiplexing Zhonghua Zhang, Junwu Kan, Guangming Cheng, Hongyun Wang, and Yonghua Jiang. Sensors and Actuators A: Physical, 1 December 2013; 203: 29-36. FGF-FGFR Signaling Mediated through Glycosaminoglycans in Microtiter Plate and CellBased Microarray Platforms. Eric Sterner, Luciana Meli, Seok Joon Kwon, Jonathan S. Dordick, and Robert J. Linhardt. Biochemistry, 17 December 2013; 52(50): 9009-9019. (MicroSys 5100 4SQ) http://www-heparin.rpi.edu/main/files/papers/52c1a9fe717cc3.08041002.pdf Expression, purification, crystallization and preliminary X-ray diffraction analysis of the aspartate transcarbamoylase domain of human CAD. Alba Ruiz-Ramos, Nada Lallous, A. Grande-García, and Santiago Ramon-Maiques. Acta Crystallographica Sect F: Struct Biol Cryst Communs, December 2013; 69(12): 1425-1430. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855736/ 2012 Human ZG16p recognizes pathogenic fungi through non-self polyvalent mannose in the digestive system. Hiroaki Tateno, Rikio Yabe, Takashi Sato, Azusa Shibazaki, Toshihide Shikanai, Tohru Gonoi, Hisashi Narimatsu, and Jun Hirabayashi Glycobiology, February 2012; 22 (2): 210-220. http://glycob.oxfordjournals.org/content/22/2/210.full Crystallographic structure of Mnk-1 and Mnk-2 proteins. Inventors: Ralf Jauch, Stefan Jakel, Kay Schreiter, Markus Wahl United States Patent: US 8129164 B2, Publication Date: 6 March 2012 https://usgene.sequencebase.com/patents/US8129164 Localized Dimerization and Nucleoid Binding Drive Gradient Formation by the Bacterial Cell Division Inhibitor MipZ. Daniela Kiekebusch, Katharine A. Michie, Lars-Oliver Essen, Jan Löwe, and Martin Thanbichler. Molecular Cell, 11 May 2012; 46(3): 245-259 http://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/MolCell2012MipZ/mipz2012supp.pdf Microfluidic devices and methods. Inventors: Abraham Lee, Philip Felgner, Armando Tovar, Uland Liao US Patent Application: US20120149600 A1, Publication Date: 14 June 2012 http://patent.ipexl.com/U2S/20120149600ZZDASHZZA1.html Structure of the regulatory domain of the LysR family regulator NMB2055 (MetR-like protein) from Neisseria meningitidis. Sarah Sainsbury, Jingshan Ren, Nigel J. Saunders, David I. Stuart, and Raymond J. Owens. Acta Crystallographica, Sect F Struct Biol Cryst Commun., 1 July 2012; 68(7): 730-737. http://bura.brunel.ac.uk/bitstream/2438/6672/2/Fulltext.pdf High-Throughput Transfection of Interfering RNA into a 3D Cell-Culture Chip. Haiyuan Zhang, Moo-Yeal Lee, Michael G. Hogg, Jonathan S. Dordick, and Susan T. Sharfstein. Small, 9 July 2012; 8(13): 2091-2098. Two crucial early steps in RNA synthesis by the hepatitis C virus polymerase involve a dual role of residue 405. Nathalie Scrima, Célia Caillet-Saguy, Michel Ventura, Déborah Harrus, Thérèse Astier-Gin, and Stéphane Bressanelli. Journal of Virology, July 2012; 86(13): 7107-7117. http://jvi.asm.org/content/86/13/7107.full.pdf+html Functional interaction analysis of GM1-related carbohydrates and Vibrio cholerae toxins using carbohydrate microarray. Chang Sup Kim, Jeong Hyun Seo, and Hyung Joon Cha. Analytical Chemistry, 7 August 2012; 84(15): 6884-6890. Bioactive cyclometalated phthalimides: design, synthesis and kinase inhibition. Sebastian Blanck, Yann Geisselbrecht, Katja Kräling, Stephen Middel, Thomas Mietke, Klaus Harms, Lars-Oliver Essen, and Eric Meggers. Dalton Transactions, 21 August 2012; 41(31): 9337-9348. Comparison of signalenhancement techniques forscreening GM crops. Atsushi Ito, Tomoyuki Taguchi, Takeyuki Mogi, Hitoshi Wake, Takeo Tanaami, Hiroshi Akiyama, ReikoTeshima, Nobuhiro Sasaki, Akiyo Yamada, Yoshihiro Ozeki Japanese J. Food Chemistry and Safety, 24 August 2012; 19(2): 141-148 (MycroSys4100) http://ci.nii.ac.jp/els/110009489101.pdf?id=ART0009957224&type=pdf&lang=en&host=cinii&order _no=&ppv_type=0&lang_sw=&no=1446059313&cp= Crystallization and preliminary crystallographic studies of FoxE from Rhodobacter ferrooxidans SW2, an Fe(II) oxidoreductase involved in photoferrotrophy. L. Pereira, I. H. Saraiva, R. Coelho, D. K. Newman, R. O. Louro, and C. Frazao Acta Crystallographica, Sect F Struct Biol Cryst Commun., 1 September 2012; 68(9): 1106-1108. http://authors.library.caltech.edu/34983/1/fw5375.pdf Structure-based characterization of the multimodularDevelopmentally Regulated GTPase in complex with the DRG family regulatory protein. Sandrea Maureen Francis PhD Theses, 10 September 2012; Universidad Autónoma de Madrid, 145 pp. (MicroSys Honeybee) http://digital.csic.es/bitstream/10261/63149/1/THESIS%20SandreaMF.pdf Analysis of density-dependent binding of glycans by lectins using carbohydrate microarrays. Xizhe Tian, Jaeyoung Pai, and Injae Shin. Chemistry, an Asian Journal, September 2012; 7(9): 2052-2060. Modeling of Piezo-Actuated Stick-Slip Micro-drives: An Overview. Ha Xuan Nguyen, Christoph Edeler, and Sergej Fatikow. Advances in Science and Technology, September 2012 (on-line); 81(Next Generation Micro/Nano Systems): 39-48. Method for detection of mutant alleles. Inventors: Geoffrey Facer, Marc A. Unger, Lincoln Mcbride EU Patent Application: EP2518161 A1, Publication Date: 31 October 2012 http://www.freepatentsonline.com/EP2518161.html Expression, purification, crystallization and preliminary X-ray diffraction analysis of the dihydroorotase domain of human CAD. Nada Lallous, Araceli Grande-Garcia, Rafael Molina, and Santiago Ramon-Maiques. Acta Crystallographica, Sect F Struct Biol Cryst Commun., 1 November 2012; 68(11):1341-5. High-Throughput Profiling of Peptide–RNA Interactions Using Peptide Microarrays. Jaeyoung Pai, Taejin Yoon, Nam Doo Kim, Im-Soon Lee, Jaehoon Yu, and Injae Shin. Journal of the American Chemical Society, 21 November 2012; 134(46): 19287-19296. Crystallization and preliminary X-ray analysis of the open form of human ecto5'-nucleotidase (CD73). Karen Maree Knapp, Matthias Zebisch, and Norbert Strater. Acta Crystallographica, Sect F Struct Biol Cryst Commun., 1 December 2012; 68(12): 1545-1549 Influence of a three-dimensional, microarray environment on human cell culture in drug screening systems. Luciana Meli, Eric T. Jordan, Douglas S. Clark, Robert J. Linhardt, Jonathan S. Dordick Biomaterials, December 2012; 33(35): 9087-9096. Carbohydrate Microarrays for Enzymatic Reactions and Quantification of Binding Affinities for Glycan–Protein Interactions. Myung-Ryul Lee, Sungjin Park, and Injae Shin. Methods Mol Biology, Carbohydrate Microarrays, 2012; 808: 103-116. 2011 Rapid simultaneous screening of seven clinically important enteric pathogens using a magnetic bead based DNA microarray. Hong Sun, Qiu-Hua Mo, Ji-Can Lin, Ze Yang, Cheng-Ning Tu, Da-Yong Gu, Lei Shi, Wei-Ping Lu. World Journal of Microbiology and Biotechnology, January 2011; 27(1): 163-169. 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