Department of Oncology: Notice of Course Offering
Oncology 425 – Advanced Topics in Cancer Research
PICK 4, ANY 4 MODULES, AND GET
3 CREDITS!
PICK ALL 8 MODULES AND GET 6 CREDITS!
Where:
When:
Fall: ECHA 2-135 / Winter: ECHA 1-148
Fall 2014 and Winter 2015
Time:
9:30 am to 10:50 am Tuesday and Thursday commencing Wednesday, September 4th, 2014
Course Description
ONCOL 425 Advanced Topics in Cancer Research *3 or *6 (fi 3 or 6) (either term, 3-0-0)
This course spans both the fall and winter terms. At least four different modules will be offered in each
term. Students can elect to take the course for 3 units of credit (total of four modules over the course of
the year) or 6 unit credits (total of eight modules over the course of the year). Each module is comprised
of 6 sessions of 80 minutes each and will be taught independently by individual instructors. Modules will
have both lecture and group discussion components. Additional modules will be added based on interest
and demand.
Module 1: Stem Cells and Cancer
Lecturer: Dr. Andrew Shaw
Module 2: Cell Signaling in Cancer
Module 3: Mitosis and Aneuploidy in
Cancer
Module 4: Genetics and Epigenetics in
Development and Cancer
Module Lecturer: Dr. Gordon Chan
Lecturers: Drs. Alan Underhill and Michael Hendzel
Module 5: Targeted and Novel Cancer
Therapeutics
Module 6: DNA Repair in Carcinogenesis and
Therapeutics
Lecturer: Dr. Mary Hitt
Lecturer: Dr. Michael Weinfeld
Module 7: Molecular Imaging of Cancer
Module 8: Genomics and Epigenomics
in Cancer
Lecturers: Dr. Frank Wuest
Lecturer: Dr. YangXin Fu
Lecturers: Drs. Michael Hendzel and Alan Underhill
Pre-requisites:
ONCOL 320 or consent of the Department.
Register early to avoid disappointment!
Contacts:
Ms. Cathy Walsh:
Phone: 780-577-8083 (Administrator)
e-mail: walsh2@ualberta.ca
Dr. Roseline Godbout:
Phone: 780-432-8901 (Coordinator)
e-mail: rgodbout@ualberta.ca
Department of Oncology: Notice of Course Offering
Oncology 425 - Advanced Topics in Cancer Research
PICK 4, ANY 4 MODULES AND GET 3 CREDITS!
PICK ALL 8 MODULES AND GET 6 CREDITS!
Module Details 2014/2015
Module 1: Stem Cells and Cancer
Week 1 - September 4, 9:
Tumour-initiation mechanisms and cell types involved
Week 2 – September 11, 16:
History of cancer stem cell research
Week 3 - September 18, 23:
Cancer stem cells as therapeutic targets
Lecturer: Dr. Andrew Shaw
Module 2: Cell Signaling in Cancer
Week 1 – September 25, 30:
Overview of signaling pathways in cancer
Week 2 – October 2, 7:
Current knowledge of signaling pathways in epithelialmesenchymal transition (EMT)
Week 3 – October 9, 14:
Notch and TGFbeta pathways in cancer
Lecturer: Dr. YangXin Fu
Module 3: Mitosis and Aneuploidy in Cancer
Week 1 – October 21, 23:
Overview of Mitosis
Week 2 – October 28, 30:
Chromosome alignment and mitotic checkpoints
Week 3 – November 4, 6:
Chromosome aneuploidy in cancer
Lecturer: Dr. Gordon Chan
Module 4: Genetics and Epigenetics in Development and Cancer
Week 1 – November 13, 18:
Transcriptional regulation and differentiation
Week 2 – November 20, 25:
Epigenetics of cancer (Part 1)
Week 3 – November 27, December 2:
Epigenetics of cancer (Part 2)
Lecturers: Drs. Alan Underhill and Michael Hendzel
Final Exam Weeks: Dec 8-19
Module 5: Targeted and Novel Cancer Therapeutics
Week 1 – January 6, 8:
Animal models and clinical trials
Week 2 - January 13, 15:
Immuno and Bio-therapeutics
Week 3 - January 20, 22:
Gene/siRNA transfer and viral therapies
Lecturer: Dr. Mary Hitt
Module 6: Carcinogenesis
Week 1- January 27, 29:
Overview of the carcinogenic process and identification of
carcinogens
Week 2 - February 3, 5:
DNA damage by physical and chemical carcinogens
Week 3 - February 10, 12:
DNA repair
Lecturer: Dr. Michael Weinfeld
Reading Week: Feb 16-20
Module 7: Molecular Imaging of Cancer
Week 1 – February 26, March 3:
Overview of molecular imaging in oncology
Week 2 - March 5, 10:
The design and preparation of molecular imaging probes
Week 3 - March 12, 17:
Applications of molecular imaging probes
Lecturers: Drs. John Mercer and Frank Wuest
Module 8: Genomics and Epigenomics in Cancer
Week 1 – March 19, 24:
Genome-wide technologies and their application in development
and cancer
Week 2 – March 26, 31:
Genomics technologies and the identification of driver and
passenger mutations in human cancers
Week 3 – April 2, 7:
Genome-wide patterns of epigenectic modifications in human
cancers and cancer stem cells
Lecturers: Drs. Michael Hendzel and Alan Underhill
Final Exam weeks: Apr 13-25