Neal K. Bangerter, Ph.D., Associate Professor Department of Electrical and Computer Engineering 449 CB, 422-4869 neal_bangerter@byu.edu Dr. Bangerter’s research focuses on developing new and more efficient techniques for generating contrast in MRI. In many cases, our quest to gather data about the brain is hampered by poor image quality, long scan times, and inadequate contrast. He and his students develop new algorithms, software, and hardware that seeks to improve the quality and capabilities of MRI as Erin D. Bigler, Ph.D., Professor Department of Psychology 1190D SWKT, 422-4289 erin_bigler@byu.edu Clinical Neuropsychology and neuroimaging investigations of typical and atypical brain development, traumatic brain injury along with aging and neurodegenerative disease. Michael D. Brown, Ph.D., Professor Department of Physiology and Developmental Biology 2029 LSB, 801-422-5859 michael_brown@byu.edu As a full time teaching professor, Dr. Brown focuses on helping students to have an excellent experience in his courses. He does not run a research lab. Dr. Brown’s previous research includes the study of axon and dendrite extension during nervous system development and regulation of the cytoskeleton during cell motility and division. David D. Busath, M.D., Professor Department of Physiology and Developmental Biology 3019 LSB, 801-422-8753 david_busath@byu.edu Dr. Busath’s research focuses on the following: mechanisms of neuronal channel structure, selectivity and gating; lipid-protein interactions; gramicidin channel structure, permeability and dynamics; mode of nerve cell invasion by Botulinum neurotoxin; Influenza virus M2 protein permeation properties. Steven K. Charles, Ph.D., Assistant Professor Department of Mechanical Engineering 435 CTB, 422-7369 skcharles@byu.edu As a biomedical engineer, Dr. Charles investigates how humans control their movements, what goes wrong in movement disorders, and how to use technology to evaluate, assist, or rehabilitate patients with movement disorders. His research draws on knowledge and practices from biomechanics, neuroscience, robotics, and rehabilitation. Alonzo D. Cook, PhD Associate Professor Chemical Engineering 350 T CB, 801-422-1611 cook@byu.edu Dr. Cook’s lab is studying peripheral nerve regeneration. He aims to stimulate the damage of peripheral nervous tissue, in order to understand the process of degeneration and subsequent regeneration. The lab is using a rat focal demyelination model in conjunction with a nerve crush injury model in order to observe the role of extracellular matrix (ECM) in its effects on the regenerative Jefferey Edwards, Ph.D., Associate Professor Department of Physiology and Developmental Biology 3046 LSB, 801-422-8080 jeffrey_edwards@byu.edu Dr. Edward’s lab studies the mechanisms mediating learning and memory as well as Reward/Addiction pathways. Using electrophysiology, pharmacology and molecular biology techniques the lab studies synaptic plasticity, the cellular mechanism allowing our brains to learn and adapt. We study synaptic plasticity in the hippocampus, the region involved in learning and memory and the ventral tegmental area, the reward region of the brain. The goal is to understand normal brain function and as a result apply this to abnormal states such as epilepsy and Alzheimer’s in the hippocampus and addiction in the ventral tegmental area. Ross Flom, Ph.D., Associate Professor Department of Psychology 1044 SWKT, 801-422-1147 flom@byu.edu Significant advances have been made in our quest to understand how various organisms, including humans, attend to multimodal or multisensory properties of their environment. Dr. Flom is interested in examining how human infants learn to attend to those properties of an event that can be specified using multiple senses, e.g., things that are seen as well as heard, as well as infants’ ability to perceive modality specific information, e.g., color, in the presence of competing information. He is also interested in examining how early and/or impaired sensory experience, i.e, prematurity of birth, blindness, hearing loss, etc. affects multisensory development in human infants. Shawn Gale, Ph.D., Associate Professor Department of Psychology 1060 SWKT, 422-9757 shawn_gale@byu.edu Dr. Gale’s research mainly focuses on neurologic populations including traumatic brain injury, epilepsy, stroke, and carbon monoxide poisoning, with an emphasis on the utiliza- tion of neuroimaging techniques and their correlation with cognition. Dawson Hedges, M.D., Professor Department of Psychology 1082 SWKT, 801-422-6357 Dawson_hedges@byu.edu Dr. Hedges research is in electroencephalography work. He investigates using event-related potential to distinguish between pathological groups and healthy controls. In his neuropsychiatric epidemiological research, he investigates social an d medical factors that contribute to cognitive function. For example, in a recent study, he studied the effects of chronic infection on cognitive ability in middle-aged adults. J. Dee Higley, Ph.D., Professor Department of Psychology 1042 SWKT, 801-422-7139 dee_higley@byu.edu Dr. Higley’s research is focused on individual differences in developmental outcomes and psychopathology and focuses on the importance of parental and other environmental influences and genetic influences on the developing brain and its behavioral correlates. His research assesses the role of these factors on addiction, adding new perspectives on how genetic and environmental influences interact to produce behavioral outcomes. Research from his laboratory shows that traits such as impulse control, aggressiveness, and sociality competence are mediated by CNS serotonin functioning and that psychopathological behaviors such as severe impulsivity and alcohol abuse are found in subjects with impaired central serotonin activity. A second line of research studies the effect of gene X environment interactions. This research shows that psychopathological outcomes are a result of early parental treatment (or the lack thereof) which is modulated by genetic background. Julianne Holt-Lunstad, Ph.D, Associate Professor Department of Psychology 1024 SWKT, 801-422-1324 Julianne.holt-lunstad@byu.edu Dr. Holt-Lunstad’s research examines the association between our social relationships and physical health and longevity, the pathways (e.g., cardiovascular, neuroendocrine, genetic, metabolic, immune, and neural) by which this association occurs, potential moderating factors, and how relationships may be applied in interventions aimed at improving health and reducing risk. Her work is interdisciplinary and takes a multilevel approach—utilizing diverse methods (self-report, biological, and behavioral data) and concepts. Ramona O. Hopkins, Ph.D., Professor Neuroscience Director Department of Psychology 1082 SWKT, 422-1170 mona_hopkins@byu.edu Dr. Hopkins’ research focuses on brain-behavior relationships. One area of the research examines the effect of critical illness on cognitive and psychological function and brain imaging. She also focuses on memory. Allan M. Judd, Ph.D., Professor Department of Physiology and Developmental Biology 2025 LSB, 801-422-3179 allan_judd@byu.edu Interaction between the immune system, endocrine system, and nervous system. Effects of the immune system hormones upon the release of hormones from the adrenal cortex; determination of the role that arachidonic acid may play in the release of anterior pituitary hormones; determination of the mechanisms involved in the release of arachidonic acid from anterior pituitary cells. Keoni Kauwe, Ph.D., Associate Professor Department of Biology 4146 LSB, 422-2993 kauwe@byu.edu Dr. Kauwe is interested in the architecture of complex traits. His current work is focused on using genomic level data to understand the regulation of protein levels in the cerebrospinal fluid. Specifically, his lab is implementing an "endophenotype-based" approach to understanding the genetic component of risk and rate of progression of Alzheimer's disease. In this approach they first identify genetic factors that are associated with different levels of key Alzheimer's disease proteins, such as amyloid beta and tau. Those genetic factors are then tested for influences on risk or rate of progression of Alzheimer's disease. The work in Dr. Kauwe’s lab is focused on data analysis and bioinformatics. Brock Kirwan, Ph.D.., Assistant Professor Department of Psychology 1052 SWKT, 422-2532 kirwan@byu.edu Dr. Kirwan is interested in how the brain forms and retains long-term declarative memories. He uses functional MRI (fMRI), event-related potentials, and behavioral testing techniques in my research. More information about my lab can be found at kirwanlab.org Michael J. Larson, Ph.D., Associate Professor Department of Psychology 244 TLRB, 801-422-6125 michael_larson@byu.edu Utilizing a convergence of information from neuropsychology and cognitive neuroscience methodologies to examine the mechanisms of cognitive dysfunction following traumatic brain injury (TBI). Event-related potentials (ERPs) and functional magnetic resonance imaging (fMRI) to show brain-based changes in how people monitor and manage their environment following head injury. Motivation, negative affect, and psychopathology (e.g., obsessivecompulsive disorder [OCD] and depression) in influencing cognitive control processes and concomitant brain activity. Steven Luke, Ph.D., Assistant Professor Department of Psychology 1062 SWKT 801-422-5978 Steven_luke@byu.edu The major focus of my research is reading, which is a complex activity that involves many different processes, most notably language and vision. I also study other aspects of language, such as language development and word and sentence comprehension, as well as other visual tasks, such as scene perception and visual search. Many different groups participate in my studies, including children and adolescents, second language learners, and individuals from various clinical populations. In my research I primarily use eye-tracking technology, although I also use MRI and EEG to study how the brain understands and integrates visual and language information during reading and other tasks Rebecca A. Lundwall , Ph.D., Assistant Professor Department of Psychology 1064 SWKT 801-422-5977 rebecca_lundwall@byu.edu I study the genetic and environmental influences on the development of reflexive visual attention. In particular, I ask: What single nucleotide polymorphisms or variable number tandem repeats are associated with improvement or decline in attention relative to one’s peers? What experiences ameliorate these genetic risks? In previous research I have found that certain alleles predict improvement on a reflexive attention task while others predict decline in performance. Environmental influences such as a particular home environment may modify these predictions. David McPherson, Ph.D., Professor Department of Audiology & Speech-Language Pathology 129 TLRB, 422-6458 david_mcpherson@byu.edu Dr. McPherson’s research is in the area of electrophysiology of language, brain function, and auditory development. His lab is looking at the plasticity of the speech perception and language areas of the brain and their ability to process linguistic information in both a normal and disordered individuals (i.e., speech and language disorders). As part of these studies, Dr. McPherson’s lab studies electrophysiological correlates of psychoacoustic function. The laboratory is well equipped to study all areas of sensory function. Chris L. Porter , Ph.D., Associate Professor Department of Marriage, Family and Human Development 2093 JFSB, 422-5806 chris_porter@byu.edu Research interests include the socialization of behavioral and psychophysiological components of young children's individual characteristics (temperament, emotionality) with particular interest on linkages to individual differences in emerging neural control on children's heart rate variability (i.e., cardiac vagal tone). Additional interests include familial and individual factors influencing the formation of early childhood attachment systems and familial and individual factors influencing the transition to parenting and the emergence of parenting belief systems (self-efficacy). Mikle D. South, Ph.D., Associate Professor Department of Psychology 245 TLRB, 422-4058 south@byu.edu Dr. South’s lab studies the contributions of the limbic system to the development of symptoms of autism spectrum conditions. He and his team are interested in the overlap between anxiety and autism using experiments designed to activate the amygdala, orbitofrontal cortex, and the anterior cingulate. His lab is currently involved in studies using a variety of psychophysiological measurements and EEG along with functional MRI. Michael R. Stark, Ph.D., Associate Professor Department of Physiology and Developmental Biology 3066 LSB, 801-422-9498 Michael_stark@byu.edu Dr. Stark’s research focuses on early nervous system development in vertebrates. He is primarily interested in how cells make fate decisions to become a certain cell type in the nervous system. Some of his research aims to address questions related to patterning of the nervous system, neuronal cell determination, and the molecular steps leading to cellular differentiation. Ongoing projects in the lab focus on CNS and PNS development, including the role of Pax3, FGFR4, and components of the Wnt signaling pathway in sensory neuron information. Scott C. Steffensen, Ph.D., Associate Professor Department of Psychology 1050 SWKT, 422-9499 scott_steffensen@byu.edu Research in Dr. Steffensen’s lab is devoted to the characterization of neuronal circuits and adaptive neuronal processes involved in drug abuse and natural rewarding behaviors. In animal studies, using electrophysiological, neurochemical, immunohistochemical, microscopic imaging, and behavioral methodologies, we study the role of midbrain GABA neurons in regulating dopamine neurotransmission, which is dysregulated during alcohol dependence. In human studies, using electroencephalographic techniques, we study potential peripheral biomarkers of brain dopamine and treatment strategies to elevate brain dopamine. Dr. Steffensen’s goal is to identify what molecular substrates in the midbrain adapt to chronic drug use and to subsequently explore treatment strategies that might reverse drug dependence. This research is currently funded by two NIH grants Sterling Sudweeks, Ph.D., Associate Professor Department of Physiology and Developmental Biology 3045 LSB, 801-422-8752 sterling_sudweeks@byu.edu Dr. Sudweeks studies neurotransmitter receptors that act as ion channels. These ligand-gated ion channels are involved in synaptic transmission and are implicated in several pathological conditions. They are also the pharmacological targets in many therapeutic situations. These ion channels are expressed in both the central and peripheral nervous systems. Specific receptors for the neurotransmitters gamma-aminobutyric acid (GABA), serotonin (5HT3), glycine (GlyR), and acetylcholine (nAChRs) are all members of the ligand-gated ion channel superfamily. Arminda Suli, Ph.D., Assistant Professor Department of Physiology and Developmental Biology 3048 LSB, 801-422-2646 asuli@byu.edu Dr. Suli’s particular interest is the development and innervation of mechanosensory hair cells of the lateral line system. Hair cells are specialized sensory cells that mediate hearing and balance in mammals and are additionally used as part of the lateral line system in fish and amphibians to detect prey and predators, to perform rheotais, etc. Dr. Suli also focuses on understanding the development of neurons that receive and coordinate input from multiple sensory systems. Multisensory neurons can be affected in individuals with neurological disorders such as autism, dyslexia, etc. Her lab uses optogenetic techniques to study these neurons. Jonathan J. Wisco, Ph.D., Associate Professor Department of Physiology and Developmental Biology 2028 LSB, 801-422-2402 jjwisco@byu.edu Dr. Wisco is the Director of the Laboratory for Translational Anatomy of Degenerative Diseases and Developmental Disorders. In general, the lab is interested in the anatomical validation of innovative neuroimaging and surgical techniques. Specifically, the lab focuses on the histological validation of Alzheimer's disease imaging biomarkers, and of Diffusion Tensor Imaging tractography, both in human and mouse brains. In addition, the lab is part of two multi-institutional collaborations to characterize stellate ganglion innervation of cardiac tissue to inform the effects of stellectomy surgery; and to validate a new surgical procedure to use phrenic nerve roots to restore laryngeal function after recurrent laryngeal nerve denervation. Dixon Woodburry, Ph.D., Professor Department of Physiology and Developmental Biology 4005B, 801-422-7562 Dixon_woodbury@byu.edu Dr. Woodbury’s research is in molecular neuroscience and focuses on membrane biophysics, particularly vesicle/membrane fusion and its regulation by SNARE proteins. SNARE proteins form the molecular motor that drives exocytosis and are the target of tetanus and botulinum toxin. Additional research looks at effects of alcohols and cholesterol on exocytosis. His approach is that of the classical biophysicist or reductionist