Transitioning to Symyx Notebook Transitioning to Symyx
Notebook
by Accelrys
From other Electronic Lab Notebooks (ELNs)
Transition to a Higher‐value ELN
Enterprise ELN
• Single
Single ELN configurable for multiple scientific ELN configurable for multiple scientific
domains for collaborative productivity
Domain specific ELN
Domain‐specific ELN
• Focused on productivity for specific scientists
Paper‐on‐glass ELN
• Simple electronic replacement for paper notebooks
“Four Top‐10 Pharma have expressed interest in switching their existing
interest in switching their existing chemistry ELNs.”
Why Transition to Accelrys? – Strategic
Providing global organizations with an enterprise ELN that:
with an enterprise ELN that:
•Enhances scientific workflow, •Enhances
scientific workflow
experiment, and process optimization
• Enables improved insight and management of complex scientific data •Enables compliance with standards and regulatory processes and controls
Qu
uality byy Design
Single ELN for the Enterprise
Distribute
& Share
Results
Distribute
& Share
Results
Collaborat
e & Make
Inferences
Identify
New
Opportunity
Collaborat
e & Make
Inferences
Identify
New
Opportunity
Search &
Find Data
Search &
Find Data
Accelrys ELN: Built on Solid Vision
The Four Pillars of Scientific Enterprise R&D
Distribute &
Share Results
Share Results
Collaborate & Make Inferences
Identify New Opportunity
Search & Find Data
Find Data
Generate Reports
Analyze Data
Make Decision
Reformat & Store Results in Database Capture & Process Results
Run Experiment
Modeling and Modeling
and
Simulation
Enterprise Lab Management
Setup Lab & Equipment
Data Management & Informatics
& Informatics
Plan/Design Experiment
Workflow Definition and Capture
Accelrys ELN: Enabled By Unique Platform Enterprise R&D Architecture
Scientists
R&D Manager
Lab Manager
Modeling and Simulation
d li
d Si l i
Discovery Studio
VP, R&D
Data Management
Data
Management
and Informatics
Enterprise Lab Management
LEA
Materials Studio
ELN
Web
Manufacturing
Plant Workers
Isentris
Head of IT &
Informatics
Workflow Definition
Workflow
Definition
and Capture
Registration
3rd Party, Partner 3rd
Party Partner
& ISV Apps
Pipeline Pilot
Pipeline Pilot™
Chemistry
Biology
Material Material
Science
Analytical
Analytical Instruments
ORACLE
D
Docs
D
Docs
LIMS
Text & Image Analytics
Reporting
Statistics &
Analytics
Laboratory Ops
3rd Party and ISV
Ch i t
Chemistry
3rd Party
Vendors
Bi l
Biology
Other
Symyx Notebook by Accelrys: Enterprise ELN
 Expand access to institutional knowledge and data assets enabling b
better decisions
d ii
Synthetic
& Parallel
Chemistry
 Sc
Scientists save time e t sts sa e t e
creating and reusing
scientific knowledge
Formulation
Process Chemistry
 IP protection and document workflow
 Lowers costs by integrating lab Medicinal di i l
Chemistry
Target Id &
Validation
Analytical Chemistry
operations and application consolidation
Biologics
 Partnerships to build best of breed Partnerships to build best of breed
solutions for your lab
Pharmacology
Why Transition to Accelrys? – Tactical
• Highly‐rated customer support and consulting services
• Proven partnerships – with customers and third‐party vendors
• Industry
Industry‐leading chemistry and data access leading chemistry and data access
solutions
• Information accessibility, world class chemical search and re‐use promoting internal and external collaboration
external collaboration
• Configurability
Configurability and extensibility enable rapid and extensibility enable rapid
startup
Reactions from Multiple Chemical Domains
View both conceptual and proven pathways from the ELN datasource
Find the best and most scalable pathway with medicinal & process di i l &
chemistry and literature in a single view
Access to reactions in Access
to reactions in
a non‐Accelrys ELN
Generate synthetic pathways for compounds and view relevant data for creating a plan
Now: Accelrys Pipeline Pilot and ELN provide rapid, scalable workflows
Rapid application extensions
Pipeline Pilot client
Library of re‐usable scientific productivity components
Symyx Notebook by Accelrys
Custom Pipeline Pilot Protocols
Pipeline Pilot Collections
D i
Design
Publish
Distribute
Accelrys Framework for Transitioning ELNs
Access multiple ELN repositories via ONE user interface
EEasily search, browse and il
h b
d
view experiments from multiple ELN repositories
Import legacy data to create NEW experiments in the Accelrys ELN
Symyx Notebook
Version 6.5
Process Notebook
Formulations Notebook
Version 5.4
V i 54
Version 5.4
Version 5.6
Version 5.6
The Enabling Technology: Symyx Notebook Browser web services
Discovery Notebook
Version 4.1
3rd Party ELN
Transition Strategy
Protect IP – Keep signed experiments unaltered in existing third party ELN database repository
third‐party ELN database repository.
EEnsure continued access –
ti
d
C fi
Configure Symyx Notebook S
N t b k
Browser web services to translate third‐party ELN data into Accelrys ELN format so it can be easily searched and viewed.
Re‐use legacy IP – The web services convert legacy data at runtime so scientists can clone experiments from the third‐
runtime so scientists can clone experiments from the third
party ELN into Symyx Notebook by Accelrys.
Keep your scientists in touch with their experiments.
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Recommended Transition Phases
Phase 1 – Deploy Symyx Notebook by Accelrys to new groups
Third‐party ELN Read/Write
Experiments
Third‐party Thi
d
t
ELN
Symyx Notebook by Accelrys
d/
Read/Write
Experiments
Symyx Notebook
Recommended Transition Phases
Phase 2 – Implement hybrid access with staged transitions to Symyx Notebook by Accelrys.
Third‐party ELN Symyx Notebook by Accelrys
Notebook Explorer
Symyx Notebook by Accelrys
Experiment Editor Open
Clone
Read/Write
Experiments
Third‐party ELN
Search and
Search and Browse
Experiments
Read/Write
Experiments
Symyx Notebook
Recommended Transition Phases
Phase 3‐ Access data from multiple ELNs through one UI—
y y Notebook by Accelrys
y
y
Symyx
Symyx Notebook by Accelrys Notebook Explorer
Symyx Notebook by Accelrys
Experiment Editor
O
Open
Clone
Search and B
Browse
Experiments
Third‐party Thi
d
t
ELN
Preserve
Legacy IP Read/Write
Experiments
Symyx Symyx
Notebook
How IT Works
Mapping the Legacy Data Model to Accelrys format
Example Conversion – Accelrys Services maps data from a third‐
party ELN into Accelrys format using Accelrys web services
3rd Party ELN
Background
Symyx Notebook by Accelrys
Background Form (Form Section)
Background Description (Text Section)
Materials
Material Amounts
Synthetic Chemistry Section (Materials
Section)
Products
Reaction Scheme
Reaction Scheme Section
Procedure
Procedure (Text Section)
Results and Conclusions (Sketch only)
Results and Conclusions (Text Section)
Embedded Reports (Sketch only)
Embedded Reports (File Section)
How IT Works
Read and Re‐use Legacy Data in Symyx Notebook by Accelrys
Clone legacy experiments into Accelrys format
1
2
Select Target Experiment Accelrys Web Service from external repository
p
y Extracts and Converts
Data to XML Format
3
Accelrys ELN Reads and Inserts Data into Appropriate Sections
Data Sources
Select ‘Create New From…’
Accelrys Services configures the web service to translate data from 3rd party ELN to Accelrys format
 Structures/Reactions
 Stoichiometry
 Methods/SOPs
 Embedded files
(pdf/xls/doc/images)
How IT Works
Symyx Notebook Browser web application
View legacy and new ELN experiments in a web browser
• Aids
Aids while transitioning users to the Accelrys ELN
while transitioning users to the Accelrys ELN
• Enables third‐party ELN users to easily view data in all mapped repositories
• Scientists can view metadata, materials, and the reaction in the experiment record without opening it
• PDF report of the experiment is available on‐line
• Read‐only access
Read only access
How IT Works
Symyx Notebook Browser web application
• Search criteria include metadata, structure, d
and reaction.
• Scientists can restrict searches to specific
searches to specific, mapped ELN p
repositories.
• Chemistry integrated y
g
for structure/reaction drawing.
How IT Works
Transition completed
Scientists access mapped legacy ELN repositories via Symyx
Notebook by Accelrys
y
y
Experiment Metadata
Experiment p
Materials
View Reactions
View PDF of Experiment
Making the Transition: Recommendations
Read the white paper for technical details
Contact your Account Manager or Accelrys Services to scope the project:
• Assess your current ELN deployment and business issues/needs
and business issues/needs
• Present recommendations on transition strategy, cost, and risk assessment
• Mutually
Mutually agree with you on a transition agree with you on a transition
and roll‐out strategy
• Support your transition!
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