Course Syllabus: BIOLOGY 1 (BIO101+L)
Credit Units: 4 / 5 (3 / 4 lecture + 1 laboratory)
Total Contact Hours: 4-unit: 108h (54h lecture + 54h lab)
5-unit: 162h (54h lecture + 54h lab + 54h IE)
COURSE STRUCTURE AND PURPOSE:
Biology 1 is offered for 4- and 5-unit as a 29-day intensive, face-to-face, immersion course organized into 4 learning periods. Each learning period
comprises 2 face-to-face lecture sessions, 2 face-to-face laboratory sessions, and a minimum of 15 hours of self-paced, web-based learning activities.
The purpose of Biology 1 is to get you acquainted with the major principles of Biology as the scientific study of life in order to foster a general understanding
of the diversity of life, from biological molecules, to cell diversity, to mechanisms of inheritance, to biotechnology, epigenetics, and evolution.
COURSE DESCRIPTION:
Biology 1 is a thorough introduction to modern biology that provides foundation for higher-level biology coursework. Biological function at the molecular and
cellular level is emphasized through coverage of topics that include: biomolecules and their integration into cellular structure and function, cellular
metabolism, gene expression, and molecular genetics. The latter part of the course includes coverage of biotechnology and genomics, the mechanisms of
evolution, epigenetics, and an introduction to phylogeny. Laboratory activities are designed to provide students opportunities to study concepts discussed in
lecture and to foster scientific investigation of biological phenomena.
MEETING TIMES:
TEXTBOOK INFORMATION:
Please keep in mind that your attendance is required (see below our attendance
guideline) when face-to-face classes are held.
The course meets for 4 consecutive weekends from 8:30am to 6:30pm on
Saturday and Sunday. On the first day of class, your instructor will inform you when
breaks will be scheduled.
Reece JB, Urry LA, Cain ML, Wasserman SA, Minorsky PV,
Jackson RB. Campbell biology. 10th ed. San Francisco, CA:
Pearson Benjamin Cummings; 2013.
When Lecture is held in the morning, please observe the following course schedule:
8:30am – 1:30pm – Lecture
2:10pm – 6:30pm – Laboratory
When Laboratory is held in the morning, please observe the following course
schedule:
8:30am – 12:50pm – Laboratory
1:30pm – 6:30pm – Lecture
ISBN-10: 0-321-775-651
You have additional instructional resources/materials available
to you in the course’s learning platform. Laboratory experiments
and safety instructions are also available in the course’s learning
platform.
Exam 2 takes place on the Wednesday after the last weekend of class, starting at
6:30 pm and ending 8:00pm.
1
Revisedandapprovedbythe
AcademicCommitteeonMarch
29,2016
TheIntegratedScienceProgram-ISP®-isaprogramdeveloped,owned,copyrightedandtrademarkedby
LifelongEducationInstitute.
© 2016 by Lifelong Education Institute
Course Syllabus: BIOLOGY 1 (BIO101+L)
Credit Units: 4 / 5 (3 / 4 lecture + 1 laboratory)
Total Contact Hours: 4-unit: 108h (54h lecture + 54h lab)
5-unit: 162h (54h lecture + 54h lab + 54h IE)
COURSE EXPECTATIONS AND OBJECTIVES:
This course is designed to be a participatory endeavor among you, your colleagues, and your instructors during lecture and lab with learning as the ultimate
goal. We encourage and expect you to take responsibility for your learning, bringing your life and professional experiences and prior knowledge into play in
an interactive manner. To help you fulfill this requirement try adopting a growth mindset that involves learning for the sake of learning and personal
enrichment rather than learning exclusively for the test or for a desired letter-grade in the course. Attend all lecture and laboratory sessions, be punctual,
interact with your colleagues, be curious by asking questions, and provide real-life examples of your experiences related to what is being discussed. Plan to
devote a minimum of 15 hours each week outside of class on our web-based platform. Use this time to exchange information among your classmates in the
student forums provided. Take advantage of all available learning materials in order to review content from previous classes and to prepare for upcoming
lectures and labs. The web-based platform includes several practice quizzes and exercises design to maximize learning. Keep in mind that authentic
learning extends beyond mere “memorization” and involves seeking the underlying meaning behind key concepts. And finally, we expect the following
learning outcomes once you’re finished with the coursework:
1. Understand the chemical basis of life and the organization of living systems, as well as synthesize the role of water in biological life, and the influence of
acids and bases on cellular structure and function.
2. Identify the different architectural arrangements of biological macromolecules (carbohydrates, lipids, proteins, and nucleic acids), and outline the roles and
functions these arrangements fulfill in biological processes.
3. Outline the concept of metabolism as a set of organized, enzyme-mediated reactions, within the perspective of cell energetics and the mechanism,
kinetics, and regulation of enzyme function.
4. Distinguish between prokaryotic and eukaryotic cells and explain the functions of subcellular structures (organelles and supramolecular assemblages).
5. Recognize the mechanisms that allow cellular transportation and intercellular communication/recognition.
6. Explain the processes of cellular respiration (aerobic and anaerobic) and illustrate the process of photosynthesis as it relates to the evolution and
continued sustainability of life on Earth.
7. Differentiate the cellular reproductive processes of mitosis and meiosis, including an analysis of all their phases, origins, and functions.
8. Synthesize the laws governing Mendelian genetics at the organismal level, including the chromosome theory of inheritance and its applications.
9. Understand the basis of molecular genetics, from DNA structure and function to the processes governing the flow of genetic information (gene
expression).
10. Evaluate the importance of current and potential applications of biotechnology and genomics for the future of science, with emphasis on human health.
11. Illustrate how the various theories of evolution explain the unity and diversity of life, with emphasis on the latest contributions of genomics and
biotechnology to the field.
12. Utilize tools of bioscience in an integrative manner to produce and disseminate scientific information (publishable data) that may contribute to therapies
for contemporary major human disease(s).
2
Revisedandapprovedbythe
AcademicCommitteeonMarch
29,2016
TheIntegratedScienceProgram-ISP®-isaprogramdeveloped,owned,copyrightedandtrademarkedby
LifelongEducationInstitute.
© 2016 by Lifelong Education Institute
Course Syllabus: BIOLOGY 1 (BIO101+L)
Credit Units: 4 / 5 (3 / 4 lecture + 1 laboratory)
Total Contact Hours: 4-unit: 108h (54h lecture + 54h lab)
5-unit: 162h (54h lecture + 54h lab + 54h IE)
LECTURE CONTENT OUTLINE:
Sessions
1
2
3
4
5
6
7
8
Topics
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Defining Biology. Overview of the chemical basis of life.
Levels of organization in living systems.
Water as the universal medium of life: polarity of water molecule, key water properties to sustain life on Earth.
Acids and Bases and their influence on cell structures and functions.
Structure and function of carbohydrates, lipids, proteins, and nucleic acids.
Enzymes: properties, activity, and significance.
Metabolism and Bioenergetics. Overall oxidation of glucose in cells.
Enzymatic control of metabolism.
Structure and function of Prokaryotic and Eukaryotic cells. The cell wall and the plasma membrane in detail.
The Eukaryotic cell in depth: organelles and supramolecular assemblages. The cell nucleus.
Plant and animal cell differentiation.
Mechanisms of cellular transportation and their regulation. Diffusion. Osmosis. Passive and active transport. Endocytosis and
exocytosis.
Cell communication and recognition. Cell junctions. Neurons and synapse.
Cell metabolism revisited: Cellular respiration and Photosynthesis.
The cell cycle. Mitosis and Meiosis.
Mendelian genetics (organismal level).
The chromosome theory of inheritance.
DNA structure and function. DNA replication.
Bacterial and Viral DNA.
Mechanisms and regulation of gene expression.
Historical context for evolutionary theory
Darwinian revolution and the modern evolutionary synthesis
Evolution of populations
The biological species concept and modes of speciation
The fossil record and geological time
Introduction to phylogeny and systematics
3
Revisedandapprovedbythe
AcademicCommitteeonMarch
29,2016
TheIntegratedScienceProgram-ISP®-isaprogramdeveloped,owned,copyrightedandtrademarkedby
LifelongEducationInstitute.
© 2016 by Lifelong Education Institute
Course Syllabus: BIOLOGY 1 (BIO101+L)
Credit Units: 4 / 5 (3 / 4 lecture + 1 laboratory)
Total Contact Hours: 4-unit: 108h (54h lecture + 54h lab)
5-unit: 162h (54h lecture + 54h lab + 54h IE)
LABORATORY CONTENT OUTLINE:
Sessions
Activities
Introduction to laboratory safety / the use of the light microscope / microscopy of biological specimens.
Lab Sessions
1 and 2
Lab Sessions
3 and 4
Lab Sessions
5 and 6
Lab Sessions
7 and 8
Lab. Project A: Learning to use the microscope. Visualizing human cells and plant cells under the microscope
Lab Project B: Discuss and model general anatomy of human biological cells. Collaboratively create and deliver a presentation
discussing the major functions of major cellular components.
Investigate variables that influence transport of materials into and out of biological cells through computer-models of natural phenomena.
Lab. Project A: Enzyme catalysis kit
Lab Project B: Transgenic fly online lab http://www.hhmi.org/biointeractive/transgenic-fly-virtual-lab
Lab Project C. Bacteria sequencing lab http://www.hhmi.org/biointeractive/bacterial-identification-virtual-lab
Lab. Project A:DNA extraction. Identifying mitosis in onion root cells
Lab Project B:Collaboratively create and deliver a presentation discussing the different genetic disorders and current therapies and
treatments for the disorder. Lab Project A: An introduction to Darwinian medicine/application of evolutionary biology
Lab Project B: Darwinian evolution activity. Comparative anatomy of arms between birds, bats, humans, whale flukes, and tiktaalik arm
bones
ABSENTEEISM:
Keep in mind that this is a face-to-face course. It is not a hybrid or distance learning course, and as such your attendance is expected during all lecture
and laboratory sessions. In order to obtain the full number of credits for this course, you must be present in the classroom/laboratory a minimum of 75% of
the time. Most importantly, you must sign the attendance sheet during each session for both lecture and laboratory – this is the only acceptable way to
prove attendance!
On the other hand, there are some situations that can be recognized as excused absences (such as a student’s serious illness or a death in the student’s
immediate family), as long as they are properly documented. Please visit www.integratedscienceprogram.com/academic-policies/ and read our “ISP
Guidelines on Attendance” to get acquainted with detailed provisions on absenteeism.
4
Revisedandapprovedbythe
AcademicCommitteeonMarch
29,2016
TheIntegratedScienceProgram-ISP®-isaprogramdeveloped,owned,copyrightedandtrademarkedby
LifelongEducationInstitute.
© 2016 by Lifelong Education Institute
Course Syllabus: BIOLOGY 1 (BIO101+L)
Credit Units: 4 / 5 (3 / 4 lecture + 1 laboratory)
Total Contact Hours: 4-unit: 108h (54h lecture + 54h lab)
5-unit: 162h (54h lecture + 54h lab + 54h IE)
COURSE WITHDRAWAL:
You are entitled to withdraw from the course with no financial responsibility (with full refund, except for the non-refundable application fee) if you fill-out an
online drop request by the Thursday before the second weekend of instruction. Please visit www.integratedscienceprogram.com/academic-policies/ and
read our “ISP Guidelines on Course Withdrawal” to get acquainted with detailed provisions on course withdrawal.
QUIZZES/TESTS/EXAMS GENERAL GUIDELINES:
Please make sure you are in class at least 15 minutes before the start of the quiz, test, or exam. If you are late, you will be granted admission to the room
provided nobody has finished the quiz/test/exam and left the room; however, if you do arrive late then you will NOT be granted extra time to complete the
quiz, test, or exam in question, and the scheduled assessment ending time will stand.
It is expected that you abide by the highest standards of honesty and integrity in the performance of academic assignments, quizzes, tests, and exams,
avoiding academic dishonesty in all of its forms, including cheating and plagiarism. Should a cheating or plagiarism incident occur, the instructor in charge
of the course has the authority to determine the penalty to be applied ranging from taking points off to failing the student for that assignment, quiz, test, or
exam. Please visit www.integratedscienceprogram.com/academic-policies/ and read our “ISP Guidelines on Cheating and Plagiarism” to get acquainted
with detailed provisions on academic integrity.
If you, for any reason, miss a quiz, test, or exam you should contact your instructor immediately to schedule a make-up. All missed tests must be taken
within 8 days, or within 10 days if the missed assessment is Exam 2. Unless you provide verifiable evidence documenting an emergency or educational
conflict, you are subject to make-up fees. Please visit www.integratedscienceprogram.com/academic-policies/ and read our “ISP Guidelines on Attendance”
to get acquainted with detailed provisions on quiz/test/exam make-ups.
If you are unable to complete the coursework, then you may be entitled to request an incomplete grade to be reflected in your transcript. Please visit
www.integratedscienceprogram.com/academic-policies/ and read our “ISP Guidelines on Incomplete Grade” to learn more about incomplete grade.
TAKING THIS COURSE FOR 5 UNITS:
If you are taking this course for 5 units you will need to engage in a Capstone Project since the very first day of the class. You should consult with your
instructor to define your capstone. You will be required to dedicate an additional 45 hours of work on your Capstone and to present a final paper following
the AMA format.
5
Revisedandapprovedbythe
AcademicCommitteeonMarch
29,2016
TheIntegratedScienceProgram-ISP®-isaprogramdeveloped,owned,copyrightedandtrademarkedby
LifelongEducationInstitute.
© 2016 by Lifelong Education Institute
Course Syllabus: BIOLOGY 1 (BIO101+L)
Credit Units: 4 / 5 (3 / 4 lecture + 1 laboratory)
Total Contact Hours: 4-unit: 108h (54h lecture + 54h lab)
5-unit: 162h (54h lecture + 54h lab + 54h IE)
TEST INFORMATION/SCHEDULE – 4 UNITS:
What?
Quiz 1
Lab Report 1
Exam 1
Quiz 2
Lab Present/Practicum
Exam 2
e-Quizzes
Online Participation
When?
Sat. Week 2
Sun. Week 2
Sat. Week 3
Sat. Week 4
Sun. Week 4
Wed. after last class
Tue. Week 2, 3, 4
Every week
How long?
30 min.
n/a
60 min.
30 min.
n/a
90 min.
20 min. each
n/a
Where?
Lecture Room
Lab Room/Online
Lecture Room
Lecture Room
Lab Room
TBA
Online
Online
Start Time?
8:30 am
By 6:00 pm
8:30 am
8:30 am
By 6:00 pm
6:30 pm
By 7:00 pm
n/a
What is in it?
Week 1 of Lecture
Lab. Session 1, 2, 3
Week 1 and 2 of Lecture
Week 3 of Lecture
Lab. Results from Session 7
Week 3 and 4 of Lecture
Weekly notes
Online discussion
Lab Participation
Total Course Points:
Points:
45
20
100
45
20
100
20
20
30
400
Where?
Lecture Room
Lab Room/Online
Lecture Room
Lecture Room
Lab Room
TBA
Online
Online
Online
Start Time?
8:30 am
By 6:00 pm
8:30 am
8:30 am
By 6:00 pm
6:30 pm
By 7:00 pm
n/a
n/a
What is in it?
Week 1 of Lecture
Lab. Session 1, 2, 3
Week 1 and 2 of Lecture
Week 3 of Lecture
Lab. Results from Session 7
Week 3 and 4 of Lecture
Weekly notes
Online discussion
Capstone Paper
Lab Participation
Total Course Points:
Points:
45
20
100
45
20
100
20
20
100
30
500
GRADING SCALE:
360 – 400 =
320 – 359 =
280 – 319 =
A
B
C
240 – 279 =
Below 240 =
D
F
TEST INFORMATION/SCHEDULE – 5 UNITS:
What?
Quiz 1
Lab Report 1
Exam 1
Quiz 2
Lab Presentation
Exam 2
e-Quizzes
Online Participation
Capstone Paper
When?
Sat. Week 2
Sun. Week 2
Sat. Week 3
Sat. Week 4
Sun. Week 4
Wed. after last class
Tue. Week 2, 3, 4
Every week
Wed. after last class
How long?
30 min.
n/a
60 min.
30 min.
n/a
90 min.
20 min. each
n/a
n/a
GRADING SCALE:
450 – 500 =
400 – 449 =
350 – 399 =
A
B
C
300 – 349 =
Below 300 =
D
F
6
Revisedandapprovedbythe
AcademicCommitteeonMarch
29,2016
TheIntegratedScienceProgram-ISP®-isaprogramdeveloped,owned,copyrightedandtrademarkedby
LifelongEducationInstitute.
© 2016 by Lifelong Education Institute