Delivering MORE Together
Start Your Next Medical Front End
Design with Texas Instruments
July 2012
TI Information
TI Information
– Selective
– Selective
Disclosure
Disclosure
Broad and diverse growth opportunity
e-Health / Telehealth
Consumer
medical devices
• Digital
thermometers
• Blood glucose
monitor
• Blood pressure
monitor
• Insulin pumps
• Heart rate
monitors
• Audiology (digital
hearing aids)
10th Mar 2010
Telemedicine
Diagnostic,
patient monitoring
and therapy
• ECG
• EEG
• Blood oxygen
(pulse oximeter)
• Blood pressure
• Temperature
• Ventilation/
respiration
• Defibrillators
• Implantable
devices
Medical
imaging
• Ultrasound
• CT
• MRI
• X-Ray
• Other imaging
(nuclear, positron
emission
tomography)
Medical
instruments
• Laboratory
equipment
• Dialysis machines
• Analytical
instruments
• Surgical
instruments
• Dental instruments
TI Confidential – NDA Restrictions
Source: TI & Databeans Medical 2011 (CAGR 2011 – 2016) *Includes Sensors, Opto, Memory
TI Information – Selective Disclosure
2
Delivering MORE Together
NEW INVESTMENT IN HEALTH
AND FITNESS
TI Information
TI Information
– Selective
– Selective
Disclosure
Disclosure
Texas Instruments Health and Fitness
IP Portfolio
• Processors (MSP430)
• High Performance Analog
• National IP
System & Design
Expertise
• SoC integration
• Cost & Perf optimization
…
Market Focus
Customer
Optimized
Solution
For Health
And
Fitness
ASSP
(AFEx)
• Health and Fitness
• Thermometers, BPM,
Pedometer, Weight/Body
Composition, PulseOx…
TI Information – Selective Disclosure
4
Delivering MORE Together
ECG / EEG / Heart Rate
TI Information – Selective Disclosure
ADS129x (Options : 1,2,4,6 and 8 Channel, 24/16-bit)
TI Information – Selective Disclosure
TI Offers a Broad Range of Choices
EXISTING
ROADMAP
Integrated Respiration impedance
measurement
600
µW/Ch.
8-CH, EEG &
High-End ECG
ADS1298
ADS1298R
8-CH, 32kSPS
24-bit
8-CH, 32kSPS
24-bit
ADS1296
ADS1296R
6-CH, 32kSPS
24-bit
6-CH, 32kSPS
24-bit
ADS1294
ADS1294R
4-CH, 32kSPS
24-bit
4-CH, 32kSPS
24-bit
ADS1196
ADS1198
6-CH, 32kSPS
16-bit
8-CH, 32kSPS
16-bit
ADS1194
4-CH, 32kSPS
16-bit
ADS1291
ADS1292
1-CH, Heart Rate 2-CH, ECG, AED
300
µW/Ch.
Power Consumption
900
µW/Ch.
ADS1299
ADS1192
1-CH, ECG, 16-bit
ADS1293
3CH, ECG, AED
ADS1191
1-CH, HR,16-bit
1μVpp
5μVpp Input Referred Noise 10μVpp
TI Information – Selective Disclosure
20μVpp
ADS1299 – Integrated Low Power AFE for EEG
Key Features:
Provides 8-Channel Simultaneous Sampling
Daisy Chainable for Higher Channel Counts
8 low noise CMOS Amplifiers (No Pop-Corn
Noise)
8 High Resolution ADC’s
Noise: <1.0uV p-p* (70Hz BW)
Input Leakage Current 50pA
CMRR : >105dB ** with G = 12
Crosstalk : >105dB
Power Dissipation: 4.0mW/Channel
Data Rates: 250SPS to 16,000SPS
Programmable Gain (1,2,4,6,8,12,24)
+ 5V / +1.8+3.3V & Bi-Polar ± 2.5V Supplies
Built in test signals
Built in Patient Bias Amplifier
Continuous Electrode Off Detection
Built in oscillator
Internal / External Reference
Flexible Power Down, STBY mode
SPI Data Interface
TI Information – Selective Disclosure
ADS1299 EEG Solution
72% lower power,95% less PWB, 98% less ICs compared to discrete
implementation
TI Information – Selective Disclosure
ADS1292/1 – 1ch, 2ch AFE for ECG
TI Information – Selective Disclosure
ADS1291 – Heart Rate Solution
TI Information – Selective Disclosure
ADS1293
Fully Integrated AFE for Portable ECG
28 Pin LLP, 5x5x0.8mm
12
TI Information – Selective Disclosure
Low Power, Scalability and Ease of Use
 Optimized For Battery Powered Monitoring
 Lowest system power solution (1mW for 5 Leads, full function)
 268uW/CH signal path
 Flexible power management
 Scalable From Single Lead Designs To 12 Leads
 One IC covers all types of portable ECGs
 Built-in Features Make It Easy to Implement
 Fully flexible routing allows any inputs being connected to any
channels
 Automatic AC/DC Lead Off Detection
 Right Leg Drive
 Comprehensive diagnosis with an Alarm pin
 Simultaneous Digital Pace Signal output with ECG signal
TI Information – Selective Disclosure
Scalable Architecture: 3/5/12 lead Applications
Five Lead ECG application using ADS1293
350uA, 1.05mW@3V
14
TI Information – Selective Disclosure
Delivering MORE Together
Weigh Scale / Body
Composition
TI Information – Selective Disclosure
AFE4300 Integrated Impedance Measurement AFE
TI Information – Selective Disclosure
AFE4300: Weight Scale / Body Composition
TI Information – Selective Disclosure
Delivering MORE Together
Pulse Ox
TI Information – Selective Disclosure
AFE4400 Integrated Solution for Photometry
1Q 2013
Release
TI Information – Selective Disclosure
Delivering MORE Together
Authentication
TI Information – Selective Disclosure
BQ2026 – Single Wire Asset Identification
Device
TI Information – Selective Disclosure
BQ2026 Application
TI Information – Selective Disclosure
Avoid Low Quality Counterfeit Cables with a
Low Cost Cable Identification Solution using
BQ2026!
TI Information – Selective Disclosure
Delivering MORE Together
NEW INVESTMENT IN
IMAGING
TI Information
TI Information
– Selective
– Selective
Disclosure
Disclosure
Boldly Investing in Medical Imaging
X-ray
CT
• Front-end for flat panel detectors (FPD)
• AFE family includes all circuitry to convert
the charge packets from the FPD to a
digital output
• Investing in new packaging options and
16-bit, 256-channel AFE
• Proven DDC product development with
almost 20 years of experience
• Upgradable DDC family with same
topology
• Investing in 256-channel DDC
Ultrasound
MRI
• Over 10 years of application specific
products, over 20 products released.
• Strong market lead with highperformance AFE58xx family
• Investing in in-probe electronics for
handheld systems
• First to market silicon-based preamplifier for coils
• Complete line of non-magnetic package
offerings
• Investing in next generation integration
of ADC and VGA
Resulting in …
experience, innovation and focus
to keep us and our customers ahead of key market trends.
TI Information – Selective Disclosure
TI Information – Selective Disclosure
Delivering MORE Together
MRI System
TI Information – Selective Disclosure
MRI System
TI Information – Selective Disclosure
ADS5263
4-Channel, 14/16-bit 100MSPS ADC
IN1B_P
IN1A_P
IN1A_M
LVDD
AGND
AVDD
16
bit16
FE
bit
16
16 bit ADC
FE
bit
16
16 bit ADC
bitFE
16 bit ADC FE
SERIALIZER
14 bit
ADC
14 bit
DIGITAL
DIGITAL
DIGITAL
DIGITAL
ADC
14 bit
14ADC
bit
ADC
16 bit ADC
Key features and benefits
LGND
SERIALIZER
SERIALIZER
SERIALIZER
SERIALIZER
SERIALIZER
Channel 4
Channel 3
Channel 2
Channel 1
OUT1P
OUT1M
SERIALIZER
SERIALIZER
OUT1P
OUT1M
IN1B_M
Differential /
single-ended
Input clock
Sync
Signal
Serializer
Clocks
LCLKP
LCLKM
BIT CLOCK, 8X
CLOCK
BUFFER
CLOCKGEN
PLL
FRAME CLOCK, 1X
ADCLKP
ADCLKM
ADC CONTROL
SDOUT
RESETZ
SCLK
CSZ
PDN
SYNC
VCM
REFB
REFT
INT/EXTZ
SDATA
SERIAL
INTERFACE
REFERENCE
ISET
CLKP
CLKM
Clamp
Signal
ADC
Clocking
Number of Channels
4
Power
380 mW/ch; 100 MSPS @ 16-bit
Full-Scale Input Range
4Vpp (16-bit); 2Vpp (14-bit)
SNR/Bits, Fin = 10 MHz
84.6 dBFS / 16-bit; Fs = 100 MSPS
Package
9x9 mm VQFN-64 RGC
TI Information – Selective Disclosure
• 16-bit resolution with up to
100 MSPS sampling
frequency for highest
performance
• SNR of 84.6 dBFS at 10 MHz
for best image quality
• Low-power consumption of
380 mW/channel for compact
medical imaging systems
• 14-bit and 16-bit resolution
modes to switch between
low-power and high-speed,
high-resolution operation
• Quad-channel in 9 mm x
9 mm QFN package brings
50% board space savings
• Non-magnetic package
option allows for operation in
a strong magnetic field such
as in magnetic resonance
imaging (MRI) and other
high-resolution applications
28
Non-magnetic package option for clear
images in a strong magnetic field
MRI scan with regular BGA
package = image distortion
a
b
LOT9
TI Information – Selective Disclosure
MRI scan with
non-magnetic package
TL5500
NDA Required
30
LMH6517
Low-Noise High Linearity DVGA
•
•
•
•
•
•
•
•
•
•





Low noise  5.5 dB noise figure
High linearity  43 dBm OIP3 @ 200MHz
Low power  80mA/ch
0.05dB gain step accuracy; 0.5dB step size
200Ω Resistive, differential input
Low impedance, differential output
Serial & parallel programming
On chip register stores gain setting
Single 5V supply voltage; 32-pin LLP package
Frequency range of 1200MHz
 Drives low impedance filter loads  Improved
system reliability & reduces cost
 Excellent high frequency distortion performance 
Better receiver sensitivity
 Lower power consumption  Increased efficiency
 Lower total receiver noise figure
IF Sampling Receiver
Differential ADC driver
Single-ended to differential converter
IF/RF and baseband gain blocks
Oscilloscopes, data acquisition
Medical applications
EVM PART # (LMH6517EVAL-R1/NOPB, SP16160CH1RBKIT/NOPB)
1ku pricing (LMH6517 - $6.30)
TI Information – Selective Disclosure
NM Packaging Coming
Available Non Magnetic Products (-NM)






Pre Amplifier for Coil
 TL5500RGPT-NM 1.5T/3T Coil
Preamp, QFN 4x4mm, 20
Leads; RTM
Analog-Digital Converter
 ADS5263IRGCT-NM 16bit/14bit
ADC, 100MSPS, BW>130MHz:
QFN 9x9mm 64-Leads; RTM
Power Management
 TPS715A01DRBT-NM 80mA
adjustable LDO 1.2V/15V: QFN
3x3mm (DRB 8 leads); RTM
 TLC7701IDRBT-NM Micro
Power Supply Voltage
Supervisor, QFN 3x3mm (DRB
8 leads); Sample available
Analog Switch
 TS5A22362DRCT-NM 0.65ohm
DUAL SPDT ANALOG
SWITCH, QFN 3x3mm (DRC
10 Leads) Sample available
15KV ESD Diodes
 TPD2E001DRST-NM 5V
Double IO Low Cap IEC ESD
Diodes, QFN 3x3 (DRS 6Leads) Sample available
Microcontroller
 MSP430F2618TPMT-NM Ultralow-power microcontrollers 64LQFP 12x12mm PM (S-PQFPG64) Sample available
TI CONFIDENTIAL NDA RESTRICTED
TI Information – Selective Disclosure
32
Delivering MORE Together
Ultrasound System
TI Information – Selective Disclosure
System level benefits for ultrasound
Analog signal chain
FET
Driver
Tx Buffer
Amp
HV
MUX
Transducer
Embedded processing
Front End
Passive
LPF
Transmit
Beamformer
DAC
Receive
Beamformer
T/R
Switch
LNA
PGA
VCA
Mid
Analog Front
Amp + Filter
End
Amp Stage
Low
Pass
Filter
Beamformer
Control Unit
Preprocessing
Clocking
ADC
Back
End
CW (analog)
Beamformer
ADC
Spectral
Doppler
Processing
B Mode
Processing
Color/Power
Doppler
Processing
Scan Conversion
Post Processing
Plug
AC/DC Supply
With Green Mode
Controller
AC Line
System
Power
Supply
Voltage
Super.
Ultrasound OS/UI
Main Power Supply
Audio
Amp
Common Interfaces
Power
LPW
RS232
USB
1394
802.11
Backlight
Touchscreen
Memory
Interfaces
MMC/SDIO
IDE/ATA
TI Information – Selective Disclosure
System level benefits for ultrasound
Analog signal chain
Embedded processing
Front End
TX517
Tx DAC
DAC
Transducer
HV
MUX
High-
Transmit
BeamformerPerformance
DSP
T/RT/R
Switch
Switch
TX810
Receive
Beamformer
Amp Stage
LNA
PGA
VCA AFE58xx
Analog Front
Amp + Filter
End
Low
Pass
Filter
UCCxx
AC Line
ADC
TPSxx
System
Power
Mid
ADC
CW (analog)
Beamformer
AC/DC Supply
With Green Mode
Controller
Beamformer
Control Unit
Mid
HighPerformancePreprocessing
DSP
CDC
Clocking
ADS16xx
Plug
Front
end
Back
End
Color/Power
B Mode
Doppler
Back Processing
High- Processing
Spectral
Performance end
Doppler
DSP
Scan Conversion
Processing
Post Processing
Supply
Voltage
Super.
Main Power Supply
Common interfaces
DSP
Ultrasound
OS/UI
SoC/Apps.
processor
TPAxx
Audio
Amp
Interface
LPW
Power
RS232
USB
1394
802.11
Backlight
Touchscreen
Memory
interfaces
MMC/SDIO
IDE/ATA
TI Information – Selective Disclosure
System level benefits for ultrasound
TX517
Tx DAC
HV
MUX
Transducer
Front End
Ultrasound Pulser
LM96550
Front
Configurable Tx
HighTransmit
BeamformerBeamformer
Performance end
DSP
LM96570
Beamformer
Control Unit
Receive
Beamformer
T/R Switch
TX810
LM96511
Amp Stage
Analog Front
Amp + Filter
End
LM96530
LNA
Low
Pass
Filter
PGA
VCA AFE58xx
Clocking
ADC
ADS16xx
UCCxx
TPSxx
Plug
AC/DC Supply
With Green Mode
Controller
Mid
CW (analog)
Beamformer
ADC
Embedded processing
Back
End
Color/Power
B Mode
Doppler
Back Processing
High- Processing
Spectral
Performance end
Doppler
DSP
Scan Conversion
Processing
Post Processing
Analog
signal chain
Supply
System
Power
Voltage
Super.
AC Line
T/R
Switch
TX810
Mid
HighPerformancePreprocessing
DSP
CDC
More
Customer
Main Power Supply
Selection
Power
Webench
Interface
Audio
Common interfaces
DSP
Ultrasound
OS/UI
SoC/Apps.
processor
TPAxx
Audio
Amp
Interface
LPW
Power
RS232
USB
1394
802.11
Backlight
Touchscreen
Memory
interfaces
MMC/SDIO
IDE/ATA
TI Information – Selective Disclosure
ADS5292, ADS5294
8-Channel, 12/14-bit 80MSPS ADC
• Best in class SNR performance improves systems
• ADS5294 - 14-bit
sensitivity.
•75.5 dBFS SNR at 5 MHz/80MSPS
• Enables high density applications to increase channel
•78.2 dBFS SNR at 5 MHz & Decimation Filter
count without increasing power
•84 dBc SFDR at 5MHz/80MSPS
• Significantly improve SNR and filter harmonics, while reducing
•77 mW/ch at 80 MSPS (2 LVDS Wires/CH)
output data rate for narrow-band applications.
•58 mW/ch at 50 MSPS (1 LVDS Wire/CH)
• Reduces the number of interface lines and 2-wire interface
• ADS5292- 12-bit
keeps serial data rate low, for low cost FPGA.
•70 dBFS SNR at 5 MHz/80MSPS
•71.5 dBFS SNR at 5MHz & Decimation Filter
•85 dBc SFDR at 5 MHz/80MSPS
•54 mW/ch at 65 MSPS
•66 mW/ch at 80 MSPS (2 LVDS Wires/CH)
• Digital Processing Block integrates several commonly used system
functions such as two- or four-channel averaging and decimation by
two, four or eight filters.
• Digital data can be output over one or two wires of LVDS pins
per channel
ADS5292EVM
ADS5294EVM
•
•
•
•
Medical Imaging
Wireless Communication
Radar
Multi-Channel Data Acquisition
TI Information – Selective Disclosure
37
AFE58xx family for ultrasound systems
Platform/
System
Production
High
End
Mid
Range
Mid
Range
Sampling
AFE5808
AFE5807
Future
ADS5294
ADS5292
AFE5805
Portable
AFE58xx
AFE5804
Portable
AFE5801
Ultra
Portable
AFE5851
38
Time
TI Information – Selective Disclosure
Transmit Products from TI
Ultrasound Transmit/Receive Switch
Ultrasound Transmit/Receive Switch
LM96530
TX517
• 8-channel high-voltage receive side switches without
charge-injection
• Can be used for receive protection and/or receive
multiplexing with SPI™ compatible bus control
• Channel bandwidth supports 1MHz to 20MHz transducers
• Input accepts pulses and continuous-wave signals within
±60V
• Integrated output clamping diodes limit output to ±0.7V
• Low harmonic distortion HD2 at -75dBc at 5MHz
Pulser
LM96550
•
•
•
•
•
•
•
•
8-channel high-voltage CMOS pulse generator
Output pulses with ±50V and 2A peak current
Active damper with built-in blocking diodes
Built-in floating supply voltages for output stage
Up to 15 MHz operating frequency
Matched delays for rising and falling edges
Harmonic performance enables harmonic imaging
Continuous-wave (CW) operation down to ±3.3V
•
•
•
•
•
•
•
•
•
•
•
Dual channel; Voltage: 180Vpp w/ Xformer
Peak Output Current: +/-2A
Integrated:
Translator & Driver
HV1,2 Output Stages
Damping Stage (HV0)
5-Level RTZ Waveform
Low HD2 Distortion: -60dB, at 5MHz w/ Xformer
Imaging Output Frequency: ≤ 20MHz
Logic Inputs: 2.5V to 5V
Matched Delay: +/-2.5ns
Ultrasound Configurable Transmit Beamformer
LM96570
• Full control over selecting beam directions and pulse
patterns by programming individual channel parameters
• Outputs interface seamlessly with positive and negative
inputs on octal high-voltage pulser ICs
• Beamformer timing provides:
• Delay resolution of 0.78 ns
• Delay range of up to 102.4 μs
TI Information – Selective Disclosure
Software & tools for ultrasound systems
TX810
AFE5804/05
AFE5851
Medical Imaging Software
Toolkits (STK)
TI Information – Selective Disclosure
AFE5801
AFE5807/08
System Block Diagrams
www.ti.com/medical
Delivering MORE Together
CT Update
TI Information – Selective Disclosure
Products/roadmap
Production
Sample
Release
DDC101
DDC316
DDC112
DDC114
DDC118
Area/Power
DDC232
DDC264
May 2006
64 Channel
3mW/channel
6ksps / 20 bit
1993
TI Confidential - Maximum Restrictions
2012
TI Information – Selective Disclosure
2013
2014
Products/roadmap
Production
Sample
Release
DDC101
DDC316
DDC112
DDC114
DDC118
Area/Power
DDC232
DDC264
DDC2256
256 channel
3.1mW/ch
2Q12
1Q13
New DDC
256 channel
1993
TI Confidential - Maximum Restrictions
2012
TI Information – Selective Disclosure
2013
2014
DDC2256 : 256 Channels
Key Features
• Complete one chip solution for measuring 256
photodiodes
• Very low noise: 5.7ppm @ 150pc FS
• Low power: 3.1mW/channel @ 3KSPS
• Built in reference buffer (OPA350) and
decoupling capacitors.
• High data rate: >8kSPS
• Adjustable full-scale: 12.5-150pC
• Easy upgrade for DDC264 users
– The migration to a 256 channel design is a
low risk using proven technology.
– Using the DDC264 design will minimize risk
and maintain performance while quickly
moving to higher density.
– The DDC2256 will include the same low
noise reference buffer (OPA350) suggested
for use with the DDC264.
TI Confidential - Maximum Restrictions
TI Information – Selective 44
Disclosure
1
2
Digital
Output
3
4
DD
C22
56
0101010
253
254
255
256
15mm x 15 mm BGA
Samples available July 2012
Release 1Q2013.
SiP will enable 4 times more silicon
per package and increase density by
over 30%.
Delivering MORE Together
X-ray
TI Information – Selective Disclosure
Flat Panel Detector Roadmap
•
•
ADS8284
18 bit
ADC
18 bit SAR
built in buffer
•
Front-end for Flat Panel Detectors
(charge input)
Outstanding performance to meet
challenging needs of medical &
security scanners
AFE Family includes all circuitry to
convert the charge packets from
the FPD to a Digital output
ADS8422
16 bit, 4 MSPS
16 bit
ADC
ADS8363
16 bit, 1 MSPS
DUAL ADC
Analog
Front End
AFE0064
AFE0256
AFE
0256
AFE2256
64 channel
256 channel
14 bit ADC
256 channel
16 bit ADC
Released
TI CONFIDENTIAL NDA RESTRICTED
2010
46
TI Information – Selective Disclosure
2011
AFE0256 256 Channels
Key Features
• 256 channel front end for flat panel arrays
• 26 μs scanning with support for binning
• Very low noise: 820 e-rms (30pF sensor cap, 1.2pC range)
• Integral Nonlinearity: ±0.006% of FSR
• 8 input ranges: 0.15pC to 9.6pC
FPD Gate Drive and Bias
AFE0256
• Built-in correlated double sampling (CDS)
• Dual banking allows data read during integration
IN1
• Selectable up or down integration
• Onboard 14 Bit ADCs with bypass option
• Sensor-reset switch included
IN2
• Low power:
2.5mW/ch w/ ext ADC,
3 mW/ch w/ internal ADC
IN256
• 0.2mW/ch sleep mode with fast startup
• 22 x 5 mm bare die suitable for gold bump
TI CONFIDENTIAL NDA RESTRICTED
47
TI Information – Selective Disclosure
AFE0256 Plug and Play EVM
TI is committed to investing in
COF/TCP package to make the
X-ray imaging product line
successful and take it to a new
level of growth and market
penetration.
TI CONFIDENTIAL NDA RESTRICTED
48
TI Information – Selective Disclosure
Web Resources
TI Medical
• TI Medical website: www.ti.com/medical
–
–
–
–
–
TI Consumer Medical website: www.ti.com/consumermedical
TI Patient Monitoring website: www.ti.com/patientmonitoring
TI Medical Imaging website: www.ti.com/medicalimaging
TI Medical Instruments website: www.ti.com/medicalinstruments
TI Telehealth website: www.ti.com/telehealth
• TI Medical Applications Guides:
www.ti.com/medicalguides
• TI Medical eNewsletter: www.ti.com/medicalenews
Thank You!