Titanium surface covered with antimicrobial coating: antibacterial
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19 ो 25 ᳳ 20150618 Chinese Journal of Tissue Engineering Research
June 18, 2015
www.CRTER.org
Vol.19, No.25
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. 19(25):4069-4075.
:2095-4344
(2015)25-04069-07
ࠄߑـġ2015-04-05
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doi:10.3969/j.issn.2095-4344.2015.25.026
Titanium surface covered with antimicrobial coating: antibacterial ability and
biocompatibility
Wang Jia-qi1, Shang Jian1, Sun Ye2, Han Xin-guang1(1Department of Orthopedics, First Affiliated Hospital
of Harbin Medical University, Harbin 150001, Heilongjiang Province, China; 2Harbin Institute of Technology,
Harbin 150001, Heilongjiang Province, China)
Wang Jia-qi, Studying for
Abstract
master’s degree, Physician,
BACKGROUND: Titanium alloy with good biocompatibility, corrosion resistance and mechanical properties have
been widely used in clinic. How to give its excellent antibacterial properties so as to cope with plant-associated
infections has become a research focus in recent years.
OBJECTIVE: To review the principle, techniques, classification and relative merits of antimicrobial coating.
METHODS: A computer-based search of Scopus database and VIP database was performed by the first author
to retrieve relevant articles published from January 1990 to January 2014 using the keywords of “titanium alloy,
plant, antibacterial, coating”.
RESULTS AND CONCLUSION: Coatings can be classified into antibiotic coating, non-antibiotic organic
antimicrobial coating, inorganic antibacterial coating, anti-adhesion coating, antibacterial bioactive polymer
coating, all of which have better biocompatibility, but also have their limitations. Current studies concerning
antimicrobial coatings mainly focus on how to enhance the binding force between antimicrobial coating and the
substrate as well as how to get a good anti-bacterial ability, biocompatibility, high wear resistance and persistence;
antibacterial phase structure and distribution effects on the bacterial colonization. The antibacterial phase
structure and distribution is the key factor for the antimicrobial properties of titanium alloys with either entirely
added anti-bacterial elements or surface coating.
ISSN 2095-4344
CN 21-1581/R
CODEN: ZLKHAH
Department of Orthopedics,
First Affiliated Hospital of
Harbin Medical University,
Harbin 150001, Heilongjiang
Province, China
Corresponding author: Shang
Jian, Professor, Chief
physician, Master’s supervisor,
Department of Orthopedics,
First Affiliated Hospital of
Harbin Medical University,
Harbin 150001, Heilongjiang
Province, China
Accepted: 2015-04-05
4069
www.CRTER.org
. Subject headings: Biocompatible Materials; Titanium; Polymers
Wang JQ, Shang J, Sun Y, Han XG. Titanium surface covered with antimicrobial coating: antibacterial ability and
biocompatibility. Zhongguo Zuzhi Gongcheng Yanjiu. 2015;19(25):4069-4075.
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