Materials Science for the 21st Century Materials Science for the 21st Century Published by National Academy of Engineering Materials Science for the 21st Century NanoEngineering is the use of Materials whose physical size, being in the nanometer regime, is the enabling feature. Materials Science for the 21st Century! In the coming years, nanotechnology will impact nearly every aspect of human life, in tangible, obvious ways. Materials Science for the 21st Century The Nanoworld Materials Science for the 21st Century Research Vision for NanoEngineering Department Materials Science and Engineering Underpinning Materials Science for the 21st Century KEY AREAS OF RESEARCH FOCUS • Avoid retaining particles in circulatory system: stealth mother ships • Reducing other organ pollution: increase targeting specificity and ability to go in and out of organs • Penetration of tumors for therapeutics and imaging: release and self-assembly of ultra small payload on specific cues • Enabling longitudinal studies: novel nano-sensors • Ex vivo genetic analysis enabled by nano-platforms Delivery via stealth porous mother ships with multi-functional payloads • smart nano sensors • tumor activated nano • platforms for therapeutics and imaging Materials Science for the 21st Century Materials Science for the 21st Century Materials Science for the 21st Century Who are the Potential Employers of NanoEngineers http://www.nanotech-now.com/directory/ Materials Science for the 21st Century Who are the Potential Employers of NanoEngineers Materials Science for the 21st Century !"#$%"&'%"%()*+&%,-&.-/0%1)#,%"&2*3(**+&),&4)0(#5&%,-&6%,#1*07,#"#38 Materials Science for the 21st Century Materials Science for the 21st Century Materials Science • ECE 15 Engineering Computation for the 21st Century • ECE 25 Introduction to Digital Design • NANO 1 The Scope of NanoEngineering (1 unit) • ECE 35 Introduction to Analog Design • NANO 101 Introduction to NanoEngineering • ECE 65 Components and Circuits Laboratory for the 21st Century Materials Science • ECE 15 Engineering Computation • ECE 25 Introduction to Digital Design • ECE 35 Introduction to Analog Design • ECE 65 Components and Circuits Laboratory • BENG 100 Introduction to Bioengineering Design (S) • BENG 101 Foundations of Biomedical Imaging (F) • BENG 103B Bioengineering Mass Transfer (S) • BENG 109 Bioengineering Statics and Dynamics (W) • BENG 130 Molecular Physical Chemistry (W) • CENG 101A Introductory Fluid Mechanics (F) • NANO 102 Foundations in NanoEngineering A: Chemical Principles • NANO 103 Foundations in NanoEngineering B: Biochemical Principles • NANO 104 Foundations in NanoEngineering C: Physical Principles • NANO 110 Modeling of NanoEngineering Systems • NANO 111 Characterization of NanoEngineering Systems • NANO 112 Synthesis and Fabrication of NanoEngineering Systems • NANO 120A NanoEngineering System Design I • NANO 120B NanoEngineering System Design II for the 21st Century Materials Science • ECE 15 Engineering Computation • ECE 25 Introduction to Digital Design • ECE 35 Introduction to Analog Design • ECE 65 Components and Circuits Laboratory • CENG 100 Process Modeling and Computation in Chemical Engineering (F) • CENG 101A Introductory Fluid Mechanics (F) • CENG 101B Heat Transfer (W) • CENG 101C Mass Transfer (S) • CENG 102 Chemical Engineering Thermodynamics (W) • CENG 113 Chemical Reaction Engineering (S) • NANO 102 Foundations in NanoEngineering A: Chemical Principles • NANO 103 Foundations in NanoEngineering B: Biochemical Principles • NANO 104 Foundations in NanoEngineering C: Physical Principles • NANO 110 Modeling of NanoEngineering Systems • NANO 111 Characterization of NanoEngineering Systems • NANO 112 Synthesis and Fabrication of NanoEngineering Systems • NANO 120A NanoEngineering System Design I • NANO 120B NanoEngineering System Design II for the 21st Century Materials Science • ECE 15 Engineering Computation • ECE 25 Introduction to Digital Design • ECE 35 Introduction to Analog Design • ECE 65 Components and Circuits Laboratory • ECE 103 Fundamentals of Devices and Materials (F,W) • ECE 134 Electronic Materials Science of Integrated Circuits (S) • ECE 135A Semiconductor Physics (F) • ECE 135B Electronic Devices (W) • ECE 136 Fundamentals of Semiconductor Device Fabrication (S) • ECE 139 Semiconductor Device Design and Modeling (S) • NANO 102 Foundations in NanoEngineering A: Chemical Principles • NANO 103 Foundations in NanoEngineering B: Biochemical Principles • NANO 104 Foundations in NanoEngineering C: Physical Principles • NANO 110 Modeling of NanoEngineering Systems • NANO 111 Characterization of NanoEngineering Systems • NANO 112 Synthesis and Fabrication of NanoEngineering Systems • NANO 120A NanoEngineering System Design I • NANO 120B NanoEngineering System Design II for the 21st Century Materials Science • ECE 15 Engineering Computation • ECE 25 Introduction to Digital Design • ECE 35 Introduction to Analog Design • ECE 65 Components and Circuits Laboratory • NANO 108 Materials Science and Engineering • MAE 130A Mechanics I: Statics (W) • MAE 131A Fundamentals of Solid Mechanics I (S) • MAE 130B Mechanics II: Dynamics (S) • MAE 105 Introduction to Mathematical Physics (F) • CENG 101A Introductory Fluid Mechanics (F) • NANO 102 Foundations in NanoEngineering A: Chemical Principles • NANO 103 Foundations in NanoEngineering B: Biochemical Principles • NANO 104 Foundations in NanoEngineering C: Physical Principles • NANO 110 Modeling of NanoEngineering Systems • NANO 111 Characterization of NanoEngineering Systems • NANO 112 Synthesis and Fabrication of NanoEngineering Systems • NANO 120A NanoEngineering System Design I • NANO 120B NanoEngineering System Design II for the 21st Century Materials Science • ECE 15 Engineering Computation • ECE 25 Introduction to Digital Design • ECE 35 Introduction to Analog Design • ECE 65 Components and Circuits Laboratory • NANO 108 Materials Science and Engineering (F) • NANO 148 Thermodynamics of Materials • NANO 150 Mechanics of Nanomaterials • NANO 158 Phase Transformations and Kinetics • NANO 161 Materials Selection in Engineering Design • NANO 168 Electrical, Dielectric, and Magnetic Properties of Engineering Materials • NANO 102 Foundations in NanoEngineering A: Chemical Principles • NANO 103 Foundations in NanoEngineering B: Biochemical Principles • NANO 104 Foundations in NanoEngineering C: Physical Principles • NANO 110 Modeling of NanoEngineering Systems • NANO 111 Characterization of NanoEngineering Systems • NANO 112 Synthesis and Fabrication of NanoEngineering Systems • NANO 120A NanoEngineering System Design I • NANO 120B NanoEngineering System Design II Materials Science for the 21st Century [1] CENG students will have taken MAE 9, while NE students will have taken ECE 15 - both are C programming courses. ECE has agreed to accept MAE 9 as a pre-req for ECE 65. [2] CENG students will have taken Chem 6BL (3 units) in an overloaded, 19-unit Spring of Freshman year, whereas NE students take Chem 6BL in a 15-unit Fall of Sophomore year. This switching of Chem 6BL from an overloaded quarter to a normally 4-unit spot leaves an open space, which can be filled by a technical elective. [3] CENG students can take BILD 1 in Fall of sophomore year of the NE curriculum in place of PHYS 2B - CENG students will have taken PHYS 2B in freshman year. [4] CENG students will have taken CENG 1 (1 unit) so need to take NANO 1 (1 unit) - they will need to take NANO 1 in Winter concurrently with NANO 101 Materials Science for the 21st Century NanoEngineering Graduate Degree Program Materials Science for the 21st Century NanoEngineering Graduate Degree Program Materials Science for the 21st Century NanoEngineering Graduate Degree Program Materials Science for the 21st Century NanoEngineering Graduate Degree Program for the 21st Century Materials Science Gaurav Arya Assistant Professor Assistant Research Scientist, NYU, 2005-2007 Postdoc, Chemical Eng., Princeton University, 2003-05 Ph.D., Chemical Eng., University of Notre Dame, 2003 B. Tech., Chemical Eng., IIT Bombay, 1998 Research Interests Statistical mechanics, biophysics, molecular modeling and simulation, nanoscale transport, polymer physics Selected Publications (4 out of 22) D. Meluzzi, D. E. Smith & G. Arya, “Biophysics of knotting”, Annual Review of Biophysics, in press (2010) A. Maitra & G. Arya, “Model for extracting intrinsic rates and activation energies from force measurements on single molecules using arbitrarily stiff devices”, Physical Review Letters, in press (2010) S. Grigoryev, G. Arya, S. Correll, C. Woodcock & T. Schlick, “Evidence for heteromorphic chromatin fibers from analysis of nucleosome interactions”, Proceedings of the National Academy of Sciences (USA) 106, 13317 (2009) G. Arya, “Energetic and entropic forces governing the attraction between polyelectrolyte grafted colloids” Journal of Physical Chemistry B, 113, 15760 (2009) for the 21st Century Materials Science Single-Molecule Force Spectroscopy Chromatin Structure and Dynamics F Our group is developing mesoscale models of We are currently developing theoretical models chromatin to understand its folding/unfolding for accurate analyses of single-molecule force dynamics. We are also studying the molecular spectroscopy data, for extracting intrinsic free mechanisms of histone modifications regulate energy barriers and rates chromatin and genes Catalytic RNAs for Gene Therapy Nanomaterials by Self-Assembly Lehnert et al. Chem. Biol. 1996, 3, 993 Our group is using a combination of bioinformatics and molecular modeling tools to efficiently design trans-splicing ribozymes for gene therapy applications We are also interested designing novel nanomaterials based on the self-assembly of functionalized colloidal particles and carbon nanotubes for the 21st Century Materials Science Dr. Jennifer Cha Materials Science for the 21st Century DNA Nanotechnology: Top-Down with Bottom-Up Nanoengineering Predictable Assembly Bio-mediated synthesis of Metal Nanostructures for the 21st Century Materials Science Dr. Sadik Esener • Professor of Nano Engineering, Electrical and Computer Engineering, and Materials Sciences at the University of California, San Diego (UCSD). • Holds a Ph.D. degree in Applied Physics and Electrical Engineering from UCSD (1987). • Director and PI of the NanoTumor Cancer Nanotechnology Center of Excellence funded by the National Cancer Institute. • Previously Director of the Center for Heterogeneously Integrated Photonics Systems (CHIPS), a multi-university DARPA funded opto-center for biophotonics and nanophotonics. Also served as the director of several university-industry consortia co-funded by DARPA. • Under his direction, his research group at UCSD has made many pioneering contributions to the fields of photonics, optical interconnects, light modulation, optical data storage, bio-optoelectronics as applied to gene chips, cell sorting and manipulation and heterogeneous integration of photonics, electronics and biological components. • He has published more than 350 journal and conferences articles, and more than 250 presentations in international scientific meetings, 75 of which were invited and he holds 15 issued patents, He has authored many book chapters, edited several proceedings, and chaired and organized over fifteen scientific international conferences. • Esener is a co-founder and served on the board of directors and scientific advisory boards of several companies including Nanogen Inc. (NGEN) that relates to his work on electrically addressed gene chips, Call/Recall Inc. that relates to his work on multilayer optical disk storage, Optical Micro Machines and Ziva Inc. that relate to his work on all optical switching and free space optics, and Genoptix (NGEN) that relates to his more recent work in biophotonics. He is a fellow of the Optical Society of America and a Member of the Regents of the Sabanci University in Turkey. for the 21st Century Materials Science Cancer Nanotechnology Photonics Photon counting cameras & nanophotonics - Monitoring and Early detection - Contrast agents for Imaging of tumors - pro-drugs and delivery vehicles activated by: • X-rays, Ultrasound, IR radiation • enzymatic reactions - Selective targeting of tumors CMOS Single Photon Avalanche Detector Drug Delivery Exploit chemical and physical approaches to deliver drugs at the desired time to externally defined spatial locations in the body to avoid side effects Ultrasound activated delivery vehicle Solid Immersion lens array for hi-res microscopy Sensors Develop unique sensor materials and devices for chemical and biological detection including for monitoring cancer Nanophotonics + Microfluidics Single molecule photonic crystal sensor Cancer recurrence monitoring for the 21st Century Materials Science Eric Fullerton Magnetic thin films and nanostructures B.S. Ph.D. Physics, Harvey Mudd College, 1984 Physics, UC San Diego, 1991 Employment Argonne National Lab IBM Research Hitachi GST UCSD 1991-1997 1997-2003 2003-2006 2009-present > 200 publications, h-factor = 38 40 US Patents on magnetic nanotechnologies Fellow of the American Physical Society Materials Science Transition metal nanowires We are using CVD to grow single crystal nanowires of transition metals and their oxides for magnetic and catalytic applications. Synchrotron x-ray techniques Use resonant synchrotron x-ray techniques including magnetic dichroism, resonant scattering, coherent scattering and microscopy to characterize nanoscale materials and devices. for the 21st Century Spintronic devices Spintronic devices exploit the spin of the electron to provide new functionality in devices. We focus our research on spininjection as a means to control the local magnetization direction in nanoscale magnetic devices. Bit patterned magnetic media Bit patterned recording media is the leading candidate for the continued growth of the areal density in magnetic hard disk drives. We have a combined theoretical and experimental study of high-density patterned arrays. Materials Science for the 21st Century Professor Michael J. Heller Professor Michael J. Heller joined the faculty at University of California, San Diego in July 2001. He has a joint appointment between the Department’s of NanoEngineering and Bioengineering. Dr. Heller was with Nanogen as CTO before joining UCSD. His experience (academic and industrial) includes many areas of biotechnology and biomedical instrumentation, with particular expertise in DNA synthesis, DNA molecular diagnostics and optoelectronic based detection technologies. Dr. Heller has been the cofounder of four high-tech companies: Integrated DNA Technologies (IDT), Nanogen, Nanotronics and most recently Biological Dynamics. Dr. Heller has been an invited speaker to a large number of scientific conferences and meetings. He has over 45 issued US patents related to microelectronic chips, microarrays and integrated devices for DNA hybridization, miniaturized sample to answer diagnostic devices, biosensors, genomics, proteomics, nanotechnology and nano-fabrication, nano-based DNA optical storage and for fluorescent energy transfer in DNA nanostructures. • • • • Panel member for the NAS (NAE) Review of National Nanotechnology Initiative 2001-2002 Panel member of NAS (NAE) – Engineer for the 2020 - 2001/2002 The White House (OSTP) National Nanotechnology Initiative 1999/2000 Involved in a number of NSF Nanotechnology Workshops Materials Science DEP Based Seamless Sample to Answer Diagnostics for Cancer Biomarkers DEP Seamless Sample to Answer - Isolation of cfc-DNA/RNA in CLL Cancer Patient Blood for the 21st Century Point-Of-Care Diagnostics: Eliminating Sample Preparation in the Detection of Disease Related Protease Activity in Whole Blood CMOS Microarray Electric Field Directed Self-Assembly of Bio-Derivatized Nanoparticle Structures for the 21st Century Materials Science Richard K. Herz UC Berkeley, PhD, Chemical Engineering GM Research Labs, Catalysis & Emission Control UC San Diego, Chemical Engineering Program Research Interests • • • • Catalysis and surface chemistry Dynamics of diffusion and reaction in porous materials Renewable energy – biomass conversion to power & fuel Interactive software simulations to engage students in active learning - www.SimzLab.com Materials Science for the 21st Century Rich Herz We study space-time patterns of reaction and diffusion in porous materials using experiments and numerical simulations. We are working with groups at UCSD, UC Berkeley, UC Davis and a biofuel company to design processes for conversion of biomass to "green" power and fuels. We work on process simulation, design and optimization. !"#$#%&'(#)*+,-&.'# /.-*0*1&02)&0#)*+34''#54'*6&7# for the 21st Century Materials Science Dr. Shirley Meng She received her Ph.D. in Advanced Materials for Micro- & NanoSystems from Singapore-MIT Alliance c/o National University of Singapore in 2005, followed by a two-year postdoctoral fellowship in Materials Science & Engineering at the Massachusetts Institute of Technology with Prof. Ceder’s group. Dr. Meng was an assistant professor at the University of Florida prior to her appointment at UCSD. She joined the Department of NanoEngineering at UC San Diego as Assistant Professor in Oct. 2009. Dr. Meng’s research interests include rational design of nanostructured materials for energy applications, both in energy conversion and energy storage, nanostructured electrodes for advanced battery technologies and thermoelectrics. Her research is strongly fundamental in nature, examining charge ordering and structural stability as the basis for structure-property relationships in advanced nanostructured materials. She has published over 25 peer-reviewed papers. Materials Science Materials Design for Advanced Energy Storage Systems for Transportation Focus on synthesizing new multi-transition metal oxides with higher energy density, faster rate capability and better safety, as well as explore the exact ion transport mechanism and structural stability during the cycling of the battery. Thermoelectric Materials - Convert Heat to Electricity Determination of the stable structures and charge/magnetic ordering is one of the most fundamental steps in obtaining optimum thermoelectric properties of ceramics. We fabricate high quality oxide films by pulsed laser deposition and characterize their figure-of-merit for thermoelectric applications. for the 21st Century Energy Storage for Renewable Energy Sources Employ a combination of theoretical and experimental approaches to develop groundbreaking energy storage schemes using new battery chemistry, as well as new nano-structured electrodes fabricated by innovative cost-effective synthetic methods to enable higher energy density and power density. Structure-Property-Processing Relations of Nano-scale Materials Work to understand how the thermodynamic and kinetic properties of these tubes/wires differ from the bulk with ab initio study, we can eliminate much guesswork and effectively prescreen candidate nano-scale materials for energy applications, applying modern synchrotron X-ray and analytical TEM to explore the structure - property relation in nanomaterials. for the 21st Century Materials Science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for the 21st Century Materials Science !0%D#%+%=5"0='@*)#<0"%'4""*3&' 9*&EC0F20,'/%)&0)G'<057'@*)#H01%"&' WC&X#;;Y& *T<#+*& WC&X#,Y& Q*&%(*&"##N),3&),1#&G%8+&#;&;%$()0%1),3&+*";5<#G*(*-&*"*01()0%"& +*,+#(+&%,-&*,*(38&7%(H*+1),3&-*H)0*+V& Q*&%(*&/1)")Z),3&17*&*H%,*+0*,1&[)*"-&#;&#<1)0%"&,%,#[)$*(+& 1#&$/)"-&,*G&-*1*01)#,&<"%1;#(=+V& ?0#$2)=50#)*+'/21<*B%+%)G57'IA50=*+'' J*B%G20,%&' @#B%+'4)*+350=*+'(0*G)#&50='(%B0=%&'' \")3#,/0"*#1)-*& <(#$*& ]*+)0"*&& ;/+)#,& hn! 4)0(#["/)-)0&07%,,*"& Q*&%(*&),1*(;%0),3&$)#+8+1*=+&G)17&<7#1#,)0&1(%,+-/0*(+&1#&& -*H*"#<&,#H*"&07*=)0%"&+0(**,),3&1*07,)U/*+V& 10 µm Q*&%(*&0#/<"),3&<"%+=#,)0&%,-&<7#1#,)0&=%1*()%"+&1#&-*H*"#<& ,*G&7)37517(#/37</1&-)%3,#+1)0+V& for the 21st Century Materials Science PROFESSOR JAN B. TALBOT Education: PhD, University of Minnesota, Chemical Engineering BS & MS, Penn. State University, Chemical Engineering Experience: University of California, San Diego, La Jolla, CA Professor of Chemical Engineering & Materials Science, 1996 - present Associate Professor, 1990 - 1996 Assistant Professor, 1986 - 1990 Development Engineer, Chemical Technology Division, Oak Ridge National Lab, TN, 1975-1981. President, The Electrochemical Society, 2001-2002; Editor, The Electrochemical Society's Interface, 1994-1998; Fellow (2004) Chair, (new) Gordon Research Conference on Electrodeposition, New London, NH, Aug. 1996 Member, World Technology Evaluation Center Former Soviet Union Display Technology Panel, 1993-1994 Member, Department of Energy Advanced Fuel-Cell Commercialization Working Group, 1993-1994 Public Director, Board of the Society of Certified Safety Professionals, 1992-1998 Registered Professional Engineer in Tennessee, 1979-present for the 21st Century Materials Science Professor Talbot's research areas include electrodeposition of nanocomposite films, electrophoretic deposition of particles, and study of the colloidal behavior of particles used in chemical mechanical polishing (CMP). Current research projects include synthesis of solid state lighting materials, study of agglomeration of colloidal particles in CMP slurries, and electrocodeposition of nanometer-sized particles . Solid state lighting materials CMP Slurry agglomeration Abrasive Contact Pad asperity Abrasive SEM micrograph of Y2O3:Eu3+core/SiO2 shell nanoparticles SEM micrographs of electrophoretically deposited phosphor on an LED. The arrow points out some cracking around the diode in the otherwise uniform coating. for the 21st Century Materials Science Andrea R. Tao Assistant Professor, July 2009-present, Department of NanoEngineering, UC San Diego. Training: A.B., Chemistry and Physics, Harvard University, Cambridge, MA, 2002. Ph.D., Chemistry, UC Berkeley, Berkeley, CA, 2007. Postdoctoral Fellow, Institute for Collaborative Biotechnologies, UC Santa Barbara. Professional Highlights: • 1 out of 10 U.S. researchers invited to the US-China Workshop for Early Career Chemical Researchers on New Materials • International Union of Pure & Applied Chemistry, 2008 Prize for Young Chemists • University of California Office of the President Postdoctoral Fellowship, 2007-2009 • National Science Foundation Graduate Research Fellow, 2002-2005 for the 21st Century Materials Science Nanoscale Interfaces & Assembly Hybrid Nanocomposites We are exploring self-assembly processes inside polymer matrices for hierarchical, tunable nanoparticle structures. Bio-Inspired Synthesis & Assembly Rational Nanostructure Synthesis Using surface-limited reactions, we are synthesizing nanoparticles using wet chemistry with atomic control. Plasmonic Biosensing Chitosan We are utilizing biopolymers and natural materials as scaffolds for nanocrystal growth. We observe changes in the optical properties of gold nanorods to quantify molecular binding (proteins, ligands) at the metal surface. Materials Science Dr. Kenneth S. Vecchio for the 21st Century Founding Chair of the Department of NanoEngineering, UCSD Professor Vecchio completed his undergraduate education in 1983 at Carnegie-Mellon University in Metallurgical Engineering and Materials Science and his Master of Science degree in Metallurgy and Materials Science at Lehigh University in 1985. He received his Ph.D. in Materials Science and Engineering from Lehigh University in 1988. Prof. Vecchio started at UCSD in the Applied Mechanics and Engineering Sciences Dept. (1988), later to become the Mechanical and Aerospace Engineering Dept. For 10 years served as the Director of the Electron Optics and Microanalysis Facility in JSOE. Fellow of ASM International and Recipient of the 2000 Marcus Grossman Young Author Award from ASM. Prof. Vecchio’s research focuses on structure-property relations in advanced materials with emphasis on applications in dynamic loading events for both civilian and defense-related fields. Of particular interest is the processing of near-net-shape laminate materials with graded or varying structures within the laminate thickness, computational design of bulk metallic glasses, nanomaterials characterization, carbon nanotube synthesis, nanoparticulate reinforced polymers and composites, and polymer deformation modeling. He has published over 115 peer-reviewed papers, several book chapters, and 50+ conference proceedings. He holds 6 US patents, and another 6+ UCSD technology disclosures. Founder of the Company, Scoperta, Inc., a materials discovery company based in San Diego, and another of his patented technologies is licensed by Solidica Corp. in Ann Arbor, MI. for the 21st Century Materials Science Metallic-Intermetallic Laminate (MIL) Composites We focus on synthesizing microstructure controlled materials architectures to enable multi-functional composites designed to fill openings in multi-dimensional material property space. Synthesis Optimization of Carbon Nanotube Growth Computational Design of Bulk Metallic Glasses Employ a combination of theoretical and experimental approaches to develop low-cost bulk metallic glass alloys and their composites. Computational modeling of multi-element composition space to design nanoscale atomic clusters as basis of novel BMGs. Structure-Property-Processing Relations of Nitinol 75 o Rockwell C Hardness 400 C 70 o 1000 C 65 o 500 C o 900 C o 800 C 60 o 600 C o 850 C 55 o 650 C o 700 C o 50 750 C 0 10 20 30 40 Aging Time, hour 1500 o 20 C o Stress, MPa 0C o -50 C 1000 Cooling o -100 C Heating o -196 C 500 0 o 400 C o 500 C o 600 C o 0 5 10 15 20 700 C -80 Carbon Nanotubes are grown via spray pyrolysis chemical vapor deposition. The results are characterized with tools such as SEM, EDS, TEM, and XRD. Many different catalysts, substrates, and growth control methods have been studied. -40 0 40 o Temperature, C 80 We focus on understanding the influence of precipitation strengthening, texture, cold-working on the strength, hardness, transformation behavior, and the extent of shape memory and superelastic behaviors in 50NiTi and 60NiTi alloys. 50 for the 21st Century Materials Science Prof. Joe Wang Honors and Awards • 1994 Heyrovsky Medal in Electrochemistry (Czech Republic) • 1999 ACS National Award in Analytical Instrumentation • 1989 Westhafer Award (NMSU Top Researcher) • 1989-present, Chief Editor and Founder – Electroanalysis (Wiley-VCH) • 2001 ‘Citation Laureate’ Award-ISI Institute- Most Cited Scientist in Engineering in the World (1991-2001) • 2000-2003 Mannase Chair and Regents Professor (NMSU) • 2003 Honorary Professor (National University-Argentina) • 2005 Electrochemistry Communications (Elsevier) Citation Award • 2006 ACS National Award in Electrochemistry • 2007 Honorary Member, National Institute of Chemistry, Slovenia • 2007 Honorary Doctorate Causa, Complutense University, Madrid Education: B.Sc., M.Sc, and D.Sc.-Chemistry, Technion, I.I.T., Israel, 1978. Professional Appointments • 1980-88 Assistant/Associate Professor - New Mexico State University • 1988-01 Regents Professor and Mannase Chair Full Professor - New Mexico State University • 2004-2008 Full Professor and Center Director, BioDesign Institute – Arizona State University • 2008-present Full Professor, UCSD • 2007 Nanyang Professor - Nanyang Technol. University, Singapore. Publications, Presentations and Citations: • 2007 ASU Faculty Achievement Award for Cutting-Edge Research • • 2007 NSF Creativity Award • 2009 AIMBE Fellow • Author of 780 papers, 10 books and 30 book chapters, 12 patents and 250 invited lectures in International meetings. H Index: 84 • Web Page: http://ne.ucsd.edu/faculty/jwang.html Materials Science Nanomotors and Nanomachines for the 21st Century Nanomaterial-based Biosensors Activity aimed at designing powerful synthetic nanomachines, capable of performing complex tasks. New nanomotor designs and propulsion mechanisms are being investigated. The unique properties of nanoscale materials offer excellent prospects for designing powerful biosensing devices. We are exploring nanoparticle-based signal amplification and coding strategies for next-generation biosensors. Nanobiotechnology and Nanobioelectronics Novel Nanowires and Nanowire Barcodes This effort examines design of novel smart and adaptive hybrid systems integrating nanomaterials and biomolecules and the potential application of such hybrids as nanoactuators, biofuel cells, nanocarriers or nanosensors. Template-assisted electrochemical synthesis is being used for preparing novel nanowires with broad range of chemical compositions, including a metallic, semiconductor and polymeric nanowires. Nanowire barcodes are being developed for a variety of tracking/tagging applications. for the 21st Century Materials Science Dr. Liangfang Zhang He received his Ph.D. in Chemical Engineering from the University of Illinois at Urbana- Champaign (UIUC) in 2006 under the supervision of Prof. Steve Granick. He was a postdoctoral associate in the laboratory of Prof. Robert Langer at MIT during 2006-2008. He joined the Department of NanoEngineering at UC San Diego as Assistant Professor in July 2008. Dr. Zhang’s research interests focus on the design, synthesis, characterization and evaluation of nanostructured biomaterials for healthcare and other medical applications, particularly drug delivery to improve or enable treatments of human diseases. He has published over 30 peer-reviewed papers and holds 12 patents. He received the 2009 Victor K. LaMer Award from the American Chemical Society, and was a recipient of a 2009 Hellman Faculty Fellow Award. for the 21st Century Materials Science Nanomaterials Synthesis and Characterization Design and synthesize unique lipid- and polymer-based nanostructures with multiple functionalities. Cancer Nanotechnology Combinatorial Drug Delivery Exploit chemical and physical approaches to load two or more types of distinct drugs onto a single nanoparticle vehicle for combinatorial therapy. Nanotech Drugs to Treat Infectious Diseases Tumor Core Develop targeted drug delivery systems that preferentially go to tumors for cancer diagnosis, imaging and therapy. Combine nanotechnology and novel antimicrobial agents to develop new, effective and safe medications to treat skin infections with specific interests in acne vulgaris and staph infections.