A TEST BOOKLET CODE (A) TEST BOOKLET NUMBER _________________ POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION & RESEARCH, CHANDIGARH DURATION: 2 HOURS Max Marks : 125 ROLL NO. __________________ ENTRANCE EXAMINATION FOR ICMR-JRF EXAMINATION – 20XX INSTRUCTIONS TO THE CANDIDATES NB: No candidate will leave the Examination Hall before the expiry of the period of at least 60 minutes of the start of the paper. 1. Write your Roll Number clearly in the designated space on the answer sheet and on the question paper. 2. The enclosed paper contains 2 Sections. Section I (A) has 50 questions and is compulsory for all candidates with each question carrying 1 mark. Sections II and III pertain to Life Sciences (B) and Social Sciences (C). The candidate may attempt questions in one of the two sections (II (B) or III (C)). Each division of Section II (B) or Section III (C) has 100 questions and the candidate is to attempt any 75 questions in the pre-designated area of Section B or C. Candidates are required to indicate the option for section B or C. 3. In case a candidate attempts more than 75 questions in Section II (B) or Section III (C), only the first 75 attempted answers will be considered for evaluation. 4. The answer to the questions in the enclosed question paper shall be written on a separate answer sheet. Chosen alternative is to be indicated by darkening the appropriate numeral on the answer sheet e.g. Q No. 1 2 ● 3 5. Negative marking for wrong answers (responses) will be done to the tune of -0.25 mark for every incorrect answer. 6. Use of Calculators/Log Tables/ Mobile Phone is not permitted. 7. Use only black or blue ball point pen. 8. The question paper is confidential and on no account be removed from the examination hall. It must be handed over to the invigilator at the end of the examination together with the answer sheet before leaving the examination hall. 9. Candidates must not deface the question paper or the answer sheet. 10. Please dispossess yourself of any paper or material from which you may be able to derive help in the examination. If any material is recovered from your possession, you will render yourself liable to action for resorting to unfair means. 11 Smuggling by writing of questions on a piece of paper or any part of your body is liable to disciplinary action and may lead to cancellation of your examination. ((((((())))))))) 1 A Section I (A) Aptitude (compulsory for all candidates) 1. Molality is defined as: 1. 2. 3. 4. Number of moles of solute/L of solvent Grams of solute/L of solvent Number of moles of solute/Kg of solvent Number of Grams equivalent of solute/L of solvent 2. An ‘inbred’ strain of an animal refers to: 1. 2. 3. 4. Genetically undefined animal Animals bred in a laboratory Isogenic animals Immunodeficient animals 3. The limits of Pearson’s Correlation coefficient are: 1. 2. 3. 4. 0≤Y≤1 -1 ≤ Y ≤ 0 -1 ≤ Y ≤ +1 0<Y<1 4. Which of the following tests will be used for testing of mean between two groups? 1. 2. 3. 4. Students unpaired ‘t’ test Students paired ‘t’ test ANOVA Chi square test 11. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 12. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 13. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 14. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 15. xxxxxxxxxx 5. When p < 0.05, which of the following is true? 1. 2. 3. 4. Probability of type I error is less than 0.05 Probability of type II error is less than 0.05 Probability of type I error is more than 0.05 Probability of type II error is more than 0.05 6. Aspirin was first obtained from the bark of: 1. 2. 3. 4. Cinchona tree Neem tree Willow tree Eucalyptus tree 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 16. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 17. xxxxxxxxxx 7. An isotope of an element has: 1. 2. 3. 4. Same number of neutrons Same number of electrons and neutrons Same number of protons and neutrons Same number of protons 8. The branch of science that deals with cancer is known as: 1. 2. 3. 4. Serology Oncology Pathology Radiology 9. Which of the following waves cannot be transmitted through vacuum: 1. 2. 3. 4. Light waves Heat waves Sound waves Electromagnetic waves 10. Luc Montagnier and Robert Gallo are the codiscoverers of the following virus: 1. 2. 3. 4. 2 Ebola Hepatitis-B Small Pox HIV 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 18. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 19. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 20. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx A 21. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 22. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 23. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 24. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 25. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 26. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 27. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 28. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 29. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 30. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 31. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 32. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 33. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 34. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 35. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 36. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 37. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 38. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 39. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 40. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 41. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 42. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 3 A 43. xxxxxxxxxx 1. 2. 3. 4. 47. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 1. 2. 3. 4. 44. xxxxxxxxxx 1. 2. 3. 4. 48. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 1. 2. 3. 4. 45. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 49. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 1. 2. 3. 4. 46. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 50. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx Section II (B) Life Sciences 51. Which of the followings is rich in triglycerides? 1. 2. 3. 4. Chylomicrons LDL VLDL HDL 52. Which enzyme has impaired activity in Vitamin B1 deficiency? 1. 2. 3. 4. Succinate dehydrogenase Pyruvate dehydrogenase Transketolase Citrate synthase 53. Which of the following is useful for identifying amino terminal residue of proteins? 1. 2. 3. 4. Cyanogen bromide Fluorodinitrobenzene Performic acid Dansyl chloride 54. Which is the most abundant RNA in a cell? 1. 2. 3. 4. tRNA mRNA rRNA SnRNA 55. Which of the following statements concerning characteristics of histones is FALSE? 1. They are highly basic proteins found in the nucleus 2. They form non-covalent bonds with eukaryotic DNA called nucleosomes 3. They are very highly conserved proteins 4. They are associated with both prokaryotic and eukaryotic DNA 56. Which of the following is an inhibitor of protein synthesis? 1. 2. 3. 4. Pencillin Chloramphenicol Actinomycin D Bacitracin 57. The Ames test is used to: 1. 2. 3. 4. To detect bacteria To detect viruses To detect enzymes To detect mutagens 58. In which of the following tissues insulin enhances transport of glucose? 1. 2. 3. 4. Brain Lens Red blood cell Adipose tissue 59. Which class of RNA characteristically contains methylated purines and pyrimidines? 1. 2. 3. 4. tRNA mRNA rRNA 16sRNA 60. Km of any enzymatic reaction describes: 1. Reaction velocity expressed as mols per second 2. Dissociation constant of E-S complex 3. Amount of the enzyme required to convert half of the substrate to E-S complex 4. Substrate concentration to achieve half of Vmax 61. A Codon consists of: 1. 2. 3. 4. 4 One molecule of amino acyl-t RNa Two complementary base pairs Three consecutive nucleotide units Three individual nucleotides A 62. One mmol of NaCI contains: 1. 2. 3. 4. 35.5 g 35.5 mg 58.5 g 58.5 mg 63. Piezoelectric crystals are used in: 1. 2. 3. 4. NMR imaging Crystallography Ultrasonography Xeroradiography 64. Nuclear Magnetic Resonance Imaging technique is based on the gyromagnetic property of: 1. 2. 3. 4. Neutron Electron Proton Positron 65. Hydrogen-3 is a pure: 1. 2. 3. 4. Alpha emitter Gamma emitter Beta emitter Positron emitter 72. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 73. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 74. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 75. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 76. xxxxxxxxxx 66. When a positron is emitted from a radioisotopic atom, the atomic number of the daughter product: 1. 2. 3. 4. Increases by one Decreases by one Decreases by two No change 67. The sedimentation velocity of a protein in a centrifuge tube does NOT depend on the: 1. 2. 3. 4. Density of the solution Density of protein Mass of protein Charge of the protein 68. Which law states that: At constant temperature, the volume of a given quantity of any gas is inversely proportional to the pressure upon the gas? 1. 2. 3. 4. Boyle’s law Charle’s law Henry’s law Dalton’s law 69. Western blot is a technique used for: 1. 2. 3. 4. Protein expression DNA expression RNA expression Fat expression 70. When a molecule absorbs light of a particular wavelength and continues to emit light of higher wavelength for a considerable time after excitation, the phenomenon is called: 1. 2. 3. 4. Phosphorescence Fluorescence Chemiluminescence Cerenkov radiations 71. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 77. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 78. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 79. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 80. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 81. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 82. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 5 A 83. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 84. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 85. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 86. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 87. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 88. xxxxxxxxxx 1. 2. 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3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 103. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 104. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx A 105. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 106. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 107. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 108. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 109. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 110. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 111. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 112. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 113. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 114. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 115. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 116. 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xxxxxxxxxx xxxxxxxxxx 144. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 145. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 146. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 147. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 148. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx A 149. xxxxxxxxxx 1. 2. 3. 4. 150. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx Section III (C) Social Sciences 51. Which of the following is the correct Dental Formula of the primitive Eutherian mammal? 1. 2. 3. 4. 3143/3143 2343/2343 3413/3413 4323/4323 52. Which of the following is NOT a fossil? 1. 2. 3. 4. Stone tools Petrified remains of the bones Lucy Coprolites 53. Which of the following methods is used for dating the fossils older than 75000 years? 1. 2. 3. 4. Carbon dating Potassium argon method Dendrochronology Density 54. The name of the book Charles Darwin wrote is: 1. 2. 3. 4. Origin of species Natural history Origin of man Process and product 55. During the last fifty years the adult height of Japanese has increased. This is known as: 1. 2. 3. 4. Secular trend Medronic trend Physique Growth gradient 56. Which of the following is the crippling disorder that results from excessive consumption of Khesari daal? 1. 2. 3. 4. Endemic goitre Marasmus Malaria Lathyrism 57. Bushman and Hottentots are the racial groups found in: 1. 2. 3. 4. South India South Africa South America Central Europe 58. Khasis are the tribes inhabiting: 1. 2. 3. 4. Nilgiri hills of South India Himachal Pradesh Madhya Pradesh North-East India 59. Ring tailed lemurs are found in: 1. South America 2. Sri Lanka 3. Southeast Asia 4. Madagascar islands 60. Introns are those segments of DNA which are: 1. Directly responsible for producing specific traits 2. Responsible for controlling the activities of structural genes 3. Non functioning spacer segments within a structural gene 4. Structural genes coding for various traits 61. Among primates the bilophodont molars are found among: 1. 2. 3. 4. Old world monkeys New world monkeys Lemurs Marmosets 62. Which of the following genera is the earliest human ancestor: 1. 2. 3. 4. Sivapithecus Dryopithecus Australopithecus Aplidium 63. Bitot’s spot is caused due to deficiency of which of the following vitamins: 1. 2. 3. 4. Vitamin B-12 Vitamin E Vitamin A Vitamin C 64. Micro-blades are the characteristic tool types of the following phase of human prehistory: 1. 2. 3. 4. Lower palaeolithic Mesolithic Upper palaeolithic Middle palaeolithic 65. The diploid number of chromosomes in man is: 1. 2. 3. 4. 64 23 32 46 66. The study approach that involves application of evolutionary principles to the behavior of animals is known as: 1. 2. 3. 4. Paleontology Sociobiology Zoogeography Paleo-primatology 67. In India a Homo erectus fossil skull cap was found in: 1. 2. 3. 4. Shivalik Hills Kaveri basin Narmada basin Ganga basin 9 A 77. xxxxxxxxxx 68. Haemophilia, a sex linked disease affecting only males, is: 1. 2. 3. 4. Recessive X-linked Dominant X-linked Y-linked Dominant autosomal 69. Array is: 1. Comparing a number of people affected by a disease and who are at risk 2. Another alternative in displaying data pictorially and allowing rapid assimilation of finding by the reader 3. A display where the horizontal and vertical axes of a graph are formed according to the scale values and the frequencies of the distribution respectively 4. A systematic arrangement of the gathered data either in an ascending or descending order 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 78. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 79. xxxxxxxxxx 1. 2. 3. 4. xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx 80. xxxxxxxxxx 70. Incidence: 1. Is the number of cases that will occur within a population during a specified period of time 2. Indicates what proportion of a given population is affected by a condition at a given point of time 3. The ratio of the number of people affected by a disease compared to a number of people at risk in a given population 4. 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