transducers Transducer Selection Chart Below is a chart that details which amplifier is used for measurement of a specific physiological parameter. Follow down the left hand column until you reach the parameter you want to measure and then move towards the right until you reach the column that displays the species you are studying may be a single transducer/sensor or multiple units to select from. Please see individual pages for complete product details. Transducer Selection Chart Physiological Signal Amplifier Left Ventricular Pressure-Volume MPVS Ultra Mouse and Rat MPVS Ultra All animals PY2 72-9739 PY2 72-9724 Some typical cardiovascular setups are shown below. Pressure-Volume Measurement transducers 2F Pressure-volume catheter, SPR-838 MPVS Ultra Hardware Cardiovascular For Blood Pressure Measurements Left Ventricular Pressure (LVP) TAM-A HEC-10D Cable PY2 73-0065 PY2 72-9843 Aortic Pressure (AP) TAM-A PY2 73-0065 Venous Pressures (VP) TAM-A TAM-D PY2 73-0065 PY2 73-1793 Pulmonary Artery pressure (PAP) TAM-A PY2 73-0065 Aortic Flow (AF) TTFM PY2 73-0146 Carotid Artery Flow (CAF) TTFM PY2 73-0146 Femoral Artery Flow (FAF) TTFM PY2 73-0146 Coronary Artery Flow (CF) TTFM PY2 73-0146 ECG ECGA EGM WLA PY2 73-0149 PY2 73-1778 PY2 73-1779 MAP BPA MAPM 3ch MAPM 6ch PY2 73-0153 PY2 73-3080 PY2 73-1780 Sement Length, Wall Thickness EIM** SNM** PY2 73-0222 PY2 73-0218 Wall Thickening EIM** DDM** PY2 73-0222 PY2 73-0785 Temperature TCAM PY2 73-1792 Aortic Pressure APT 300 TAM-A TAM-D Venous Pressure (P75) For Blood Flow Measurements Pressure-Volume Catheters Peripheral, Coronary Flow TTFM J2 Aortic Flow Harvard Apparatus • phone 508.893.8999 • toll free U.S. 800.272.2775 • fax 508.429.5732 • www.harvardapparatus.com Rat/Guinea Pig Rabbit/Cat Dog Pig PVR-1045 PVR-1035 PVR-1030 SPR-839 PY2 72-9721 PY2 72-9722 PY2 72-9740 PY2 72-9723 SPR-869 SPR-838 PY2 72-9745 PY2 72-9736 SPR-550 SPR-554 SPR-560 Notes Notes Notes SPR-550 SPR-554 SPR-560 SPR-562 Notes Notes PY2 72-9767 PY2 72-9729 SPR-560 SPR-562 SPR-570 SPR-592 PY2 72-9767 PY2 72-9722 Notes PY2 72-9729 SPR-1000 PY2 72-9781 SPR-671 SPR-407 PY2 72-9779 PY2 72-9775 SPC-320 SPC-330 SPC-340 Notes Notes Notes SPC-350 SPC-360 SPC-370 Notes Notes Notes SPC-350 SPC-360 SPC-370 Notes Notes Notes APT300 PY2 73-3862 PY2 73-3862 PY2 73-3862 PY2 73-3862 PY2 73-3862 P75 PY2 73-0020 PY2 73-0020 PY2 73-0020 PY2 73-0020 PY2 73-0020 P75 PY2 73-0020 PY2 73-0200 PY2 73-0200 PY2 73-0200 PY2 73-0200 1.0PRB 1.5PRB PY2 73-4091 PY2 73-4093 2PSB 2.5PSB PY2 73-4068 PY2 73-4070 4PSB 6PSB 8PSB PY2 73-4075 PY2 73-4077 PY2 73-4079 14AX 16AX 20AX 28AX PY2 73-4095 PY2 73-4096 PY2 73-4097 PY2 73-4099 16AX 20AX 24AX 28AX PY2 73-4096 PY2 73-4097 PY2 73-4098 PY2 73-4099 0.5VB 0.75VB PY2 73-4066 PY2 73-4067 1PRB 1.5PRB 2PSB PY2 73-4091 PY2 73-4093 PY2 73-4068 1.5PRB 2PSB 2.5PSB PY2 73-4093 PY2 73-4068 PY2 73-4070 3PSB 4PSB 6PSB 8PSB PY2 73-4073 PY2 73-4075 PY2 73-4077 PY2 73-4079 8PSB 10PSB 12PSB 14PSB 16PSB PY2 73-4079 PY2 73-4081 PY2 73-4083 PY2 73-4085 PY2 73-4087 0.5VB 0.75VB PY2 73-4066 PY2 73-4067 1PRB 1.5PRB 2PSB PY2 73-4091 PY2 73-4093 PY2 73-4068 1.5PRB 2PSB 2.5PSB PY2 73-4093 PY2 73-4068 PY2 73-4070 3PSB 4PSB 6PSB 8PSB PY2 73-4073 PY2 73-4075 PY2 73-4077 PY2 73-4079 8PSB 10PSB 12PSB 14PSB 16PSB PY2 73-4079 PY2 73-4081 PY2 73-4083 PY2 73-4085 PY2 73-4087 - - - - 1PRB 2PSB PY2 73-4091 PY2 73-4068 1PRB 2PRB 3PRB PY2 73-4091 PY2 73-4068 PY2 73-4073 2PSB 3PSB 4PSB PY2 73-4068 PY2 73-4073 PY2 73-4075 comes with needle elec. comes with needle elec. Needles adhesive PY2 59-8526 PY2 73-3022 Needles adhesive adhesive PY2 59-8546 PY2 73-3022 PY2 73-3023 Needles adhesive adhesive PY2 59-8546 PY2 73-3022 PY2 73-3023 Micro PY2 73-3840 Tip PY2 73-0150 Standard PY2 73-0409 Standard PY2 73-0409 Standard PY2 73-0409 - - SA5-2 PY2 73-3463 SL5-2 PY2 73-0217 SL5-2 WT5-2 PY2 73-0217 PY2 73-0618 SL5-2 WT5-2 PY2 73-0217 PY2 73-0618 - - - - DMT20-1 DMT20-2 PY2 73-3466 PY2 73-3467 DMR-10-1 DMT-10.2 PY2 73-3464 PY2 73-3465 DMR-10-1 DMT-10.2 PY2 73-3464 PY2 73-3465 RET-3 PY2 52-1591 RET-2 PY2 52-1583 RET-1 PY2 52-1526 RET-1 PY2 52-1526 RET-1 PY2 52-1526 transducers Mouse transducers Cardiovascular Transducer Selection Chart The measurement of dimensions (wall thickness, segment length, wall thickening) requires an external amplifier system (System 6 case PY2 73-0216 with Sonomicrometer Module PY2 73-0218 or Doppler displacement Module PY2 73-0785), the signals are linked to the PLUGSYS system using the EIM module exist in different configuration, see pages J12-13 for detailed specifications and ordering information. ✐ NOTE: Please contact your local Harvard Apparatus Representative or our Technical Support Team to configure a system to your requirements. Harvard Apparatus • phone 508.893.8999 • toll free U.S. 800.272.2775 • fax 508.429.5732 • www.harvardapparatus.com J3 transducers RGBP Research Grade Blood Pressure Transducer Research Grade Blood Pressure Transducer transducers Cardiovascular An extremely versatile and accurate pressure transducer • Simple to use and robust • Transducer and Amplifier in a single compact unit • BNC output for connection to virtually any data acquisition system The RGBP transducer converts picofarad changes of capacitance into highlevel DC voltages using a unique electronic circuit (U.S. Patent #4,142,144). This circuit is extremely sensitive and stable, producing a signal suitable for direct connection to recorders, oscillographs and computers. The transducer amplifier has a 3-digit back lit LCD display that reads directly in mmHg up to 999. Amplifiers can be stacked for multiple use. It is possible on special order to have as many as 4 amplifiers operated by one transformer. Specifications Output Voltage Factory set at 1.0 V/100 mmHg via BNC connector; calibrated up to 300 mmHg Linearity ±1.5% of full scale Compliance 14 µl displacement /100 mmHg, including 305 mm (12 in) of standard 3 mm (1/8 in) ID vinyl tubing Dome Volume 300 µl Pressure Range -50 to +300 mmHg Overload Pressure 3000 mmHg Zero Offset Control -50 to +100 mmHg Natural Frequency > 500 Hz, dry Electrical Isolation > 1 kV Carrier Frequency 2 MHz Output Impedance 2 kΩ Input Liquid Connectors Dual transparent female Luer lock Drift Negligible after 5 min. warm-up Sterilization of Transducer Chemical: Alcide, Cidex, etc. Dimensions: Transducer, H x W x D 43 x 30 x 55 mm (1-1/2 x 1-1/8 x 2-1/4 in) Handle, OD x L 9.7 x 76.2 mm (3/8 x 3 in) Amplifier, H x W x D 51 x 95 x 86 mm (2 x 3-3/4 x 3-3/8 in) Display LCD, 7.6 mm (0.3 in) high numbers Weight 908 g (2 lb) Order # Product PY2 72-4496 Research Blood Pressure Transducer, 115 VAC, 60 Hz PY2 72-4497 Research Blood Pressure Transducer, 230 VAC, 50 Hz PY2 72-4498 Replacement Dome, pkg. of 1 (Older units require retrofit) The RGBP uses a semi-disposable dome of medical grade Silastic® with an integral silicone rubber diaphragm. Blood only contacts the diaphragm. Domes are supplied sterile and can be re-sterilized and reused without affecting calibration. Replacement domes are available as accessories. Please note that replacement domes listed on this page are for Harvard Apparatus’ newer model transducer ONLY. The older model is distinguished by a black threaded ring at the base of the dome. The newer models have a white ring at the base of the dome. We are no longer able to offer replacement domes for these older units. For Catheters, see pages B16 - B21. J4 Harvard Apparatus • phone 508.893.8999 • toll free U.S. 800.272.2775 • fax 508.429.5732 • www.harvardapparatus.com transducers APT300 Blood Pressure Transducer Inexpensive Reliable Accurate Low volume displacement Suitable for virtually all arterial pressure applications Easy to fill Stopcocks included Simple holder for rod mounting Replacement APT300 transducer head Replacement cable with contact plate It can be used for measurement of arterial pressure in vivo as well as for perfusion pressures in isolated perfused organs such as heart or kidney. It can also be used to measure isovolumetric left ventricular (using a balloon) pressures in isolated hearts from mice up to rabbits or pigs. Holder for APT300 transducer, 8mm rod, length 160mm Holder for APT300 transducer, 8mm rod, length 75mm The transducer consists of a contact plate with cable and the exchangeable transducer head, which can easily be replaced. Contact plates with cables for different amplifier types are available. PY2 73-3862 APT300 Pressure transducer for PLUGSYS TAM Amplifier The APT300 transducer is an inexpensive pressure transducer which can be used to measure arterial blood pressures in all species, even on mice with a high heart rate. Order # Cardiovascular • • • • • • • • transducers Pressure transducer APT300 with 3m cable and connector for PLUGSYS TAM Amplifier Product PY2 73-3863 APT300 Pressure Transducer for Harvard UK Transducer Interface PY2 73-3864 APT300 Pressure Transducer for Grass Amplifiers Specifications PY2 73-3865 APT300 Pressure Transducer for Gould 6600 Series Operating pressure -300 to 300 mmHg Overpressure 4000 mmHg Sensitivity 5 µV/V/mmHg (±1%) Temperature coefficient < 0.1% / °C PY2 73-3866 APT300 Pressure transducer for ADInstruments Bridge Amp PY2 73-3878 APT300 Pressure Transducer for DSI/PONEMAH 7700 Amplifier Zerodrift < 0.2 mmHg / °C Accessories Zero offset < 25 mmHg Excitation voltage 2 – 15 V DC (or AC up to 5kHz) PY2 73-3860 Replacement Cable with Contact plate for PLUGSYS TAM Amplifier Isolation against fluid > 5000 V PY2 73-3861 Replacement APT300 Transducer Head Operating temperature 15° to 40°C PY2 73-3868 Holder for APT300 Transducer, 8mm Rod, Length 160mm Storage temperature -25° to 70°C PY2 73-3869 Holder for APT300 Transducer, 8mm Rod, Length 75mm Volume displacement < 0.04 mm 3/100 mmHg PY2 73-0566 Perspex Block Clamp to Mount Transducer on a Rod Output impedance 356 Ohm ±1% PY2 73-0500 Stand with Block Clamp Frequency response > 1 KHz Cable length 3m Harvard Apparatus • phone 508.893.8999 • toll free U.S. 800.272.2775 • fax 508.429.5732 • www.harvardapparatus.com J5 transducers P75 Venous Pressure Transducer Blood Pressure Transducer P75 Specifications Pressure Range ±75 mmHg (±100 cmH2O) Volume Displacement 0.06 mm3 /10 mmHg Linearity ±0.15 mmHg Long-Term Drift ±0.04 mmHg Overload -760 (= vacuum) to 4000 mmHg Measurement Media All gases and liquids which do not attack Macrolon® Temperature Range 0° to 50°C Zero Drift ±0.04 mmHg/10°C (0° to 50°C) Range Drift ±0.04 mV/10°C (±0.04 mmHg/10°C) (0° to 50°C) Electrical Data: transducers Supply Voltage 5 V (4.5 to 5.5 V) DC only Current Loading 15 mA max. Sensitivity Frequency Range 300 Ω, nominal Connection Cable Approx. 1.5 m (4.9 ft) long 1 mV/mmHg, nominal Output Resistance Cardiovascular • For low pressure applications with liquids and gasses ±75mmHg • Excellent sensitivity and baseline stability • Applications include: – Venous blood pressure – Esophageal pressure with fluid filled catheter – Perfusion pressure in isolated lung and liver – Perfusion pressure on perfused hollow organs like the esophagus • Robust construction, easy to fill, bubble free The P75 has a removable Macrolon® dome with a pressure connection and a vent connection at the side, so that it can be filled free of air bubbles. The dome connections have a male Luer taper so that suitable stopcocks* can be attached. The transducer has a metal housing. The actual pressure sensor inside is made from ceramic and therefore has excellent resistance to different media. The transducer’s rugged construction can withstand pressure overloads up to 4000 mmHg without damage. It works together with any DC bridge amplifier (e.g., PLUGSYS TAM-A). See the Physiology Section I. 0 to 100 Hz Suitable Amplifiers Any bridge amp providing 5V DC excitation voltage Mechanical Data: Pressure Connections Luer taper, male Weight 0.35 kg (0.8 lb) Dimensions, HxWxD 40 x 40 x 35 mm (1.57 x 1.57 x 1.38 in) Mounting Rod, OD x L 8 x 70 mm (0.31 x 2.76 in) Order # Product PY2 73-0020 Blood Pressure Transducer P75 for PLUGSYS TAM Amplifier PY2 73-0021 Blood Pressure Transducer P75 for Harvard Apparatus Transducer Interface PY2 73-0022 Blood Pressure Transducer P75 for Grass Amplifiers PY2 73-0023 Blood Pressure Transducer P75 for Gould 6600 Series PY2 73-0024 Blood Pressure Transducer P75 for Gould 4600 Series PY2 73-0025 Replacement Dome for Venous Blood Pressure PY2 73-3738 Blood Pressure Transducer P75 for ADInstruments Bridge Amp *Use one each of PY2 73-0096 three-way stopcock and PY2 73-0097 one-way stopcock J6 Harvard Apparatus • phone 508.893.8999 • toll free U.S. 800.272.2775 • fax 508.429.5732 • www.harvardapparatus.com transducers Isolated Physiologic Pressure Transducers Specifications (continued) • Ideal for measuring pressure from venous through atrial ranges • Available in P23XL standard or P10EZ miniature size • For use with: – Harvard Apparatus UK amplifiers – PLUGSYS modules – Grass amplifiers – Protocol propac monitor – Gould electronic 6600 and 4600 series of amplifiers ±1.5 mmHg/0 to 30 mmHg Hysteresis ±0.1 mmHg/0 to 10 mmHg Cable Length 3.7 m (12 ft) Operating Temperature 20° to 40°C (68° to 104°F) Weight (Without Cable): Standard P23XL 15 g (1.46 oz) Miniature P10EZ 5 g (0.18 oz) Length (Including Dome): Standard P23XL 40 mm (1.58 in) Miniature P10EZ 37 mm (1.46 in) Isolated Physiologic Pressure Transducer Transducer with Interface Cable Amplifier Standard P23XL Miniature P10EZ Interface Cable Only Harvard Apparatus PY2 72-2461 PY2 72-2466 PY2 60-0298 HA-HSE PY2 72-2880 PY2 72-2881 PY2 72-2882 Grass PY2 72-2462 PY2 72-2467 PY2 60-0300 Propac PY2 72-2463 PY2 72-2468 PY2 60-0297 These solid state isolated pressure transducers measure from -50 to +300 mmHg with a 100 mmHg shunt cal resistor. Safety is assured by an isolated sensing mechanism and plastic case. They are defibrillator protected. Select the transducer based on your required size, pressure and equipment to be used. Domes and interface cables must be purchased separately. Gould 4600 PY2 72-2464 PY2 72-2469 PY2 60-0299 Gould 6600 PY2 72-2465 PY2 72-2470 PY2 60-0296 Transducer interface cables with integral connector are also sold separately. This permits the same transducer to be connected to different equipment. Simply purchase the necessary interface cable based on the equipment you will be using. The cable is 3.7 m (12 ft) long with a mating connector for instrument specified. Replacement reusable polycarbonate domes are available separately. They are supplied individually non-sterile (may be sterilized a limited number of times). Disposable diaphragm domes are also available and are supplied in a box of 12, individually packaged. PY2 60-0281 P10EZ Pressure Transducer without Connection Cable (Domes Ordered Separately, see below) Order # transducers PY2 60-0281 Miniature Isolated Physiologic Pressure Transducer 0.04 mm3/100 mmHg pressure Non-Linearity Cardiovascular PY2 60-0280 Standard Isolated Physiologic Pressure Transducer Volume Displacement Product PY2 60-0280 P23XL Pressure Transducer without Connection Cable (Domes Ordered Separately, see below) PY2 72-2883 Interface Cable, Universal Connector to Tinned Leads (no connector), for Use with Other Equipment, Mating Connector Required PY2 60-0283 Reusable Polycarbonate Dome for P10EZ Miniature, Luer Lock Fitting, pkg. of 1 PY2 60-0294 Disposable Diaphragm Dome for P10EZ Miniature, Rotating Luer Lock Fitting, pkg. of 12 PY2 60-0290 Reusable Polycarbonate Dome for P23XL Standard Size, Linden Fitting, pkg. of 1 Specifications Pressure Range -50 to +300 mmHg Over-Pressure Tolerance 10,000 mmHg PY2 60-0292 Disposable Diaphragm Dome for P23XL Standard Size, Rotating Luer Lock Fitting, pkg. of 12 PY2 60-0293 Disposable Diaphragm Dome for P23XL Standard Size, Standard Linden Fitting, pkg. of 12 Bridge Resistance: Input Resistance 1,000 W, nominal Output Resistance 350 W, nominal Excitation Voltage Up to 10 VAC or DC rms max., up to 5 kHz Zero Offset ±40 mmHg, max. Sensitivity 5 µV/V mmHg ±1% Thermal Coefficient: Of Sensitivity ±0.1 %/°C Of Zero ±0.3 mmHg/°C Electrical Leakage > 2 µA at 120 VAC, 60 Hz Defibrillator Withstand 400 watt-seconds, max. across 50 W load For Isometric and Isotonic Transducers, see Physiology Section I. Harvard Apparatus • phone 508.893.8999 • toll free U.S. 800.272.2775 • fax 508.429.5732 • www.harvardapparatus.com J7 transducers TRA Series Blood Pressure Transducers transducers Cardiovascular Reusable Pressure Transducer TRA021 Disposable Pressure Transducer TRA023 The Harvard Apparatus Research TRA021 is an economical, reusable blood pressure transducer suitable for routine laboratory arterial and venous blood pressure measurements. The rugged construction and dome-type design makes the TRA 021 a good general use blood pressure transducer. The Harvard Apparatus Research TRA023 is a disposable alternative to the TRA021, reusable blood pressure transducer. Suitable for most arterial and venous blood pressure measurements, the in-line design allows lower cost while maintaining measurement accuracy. The TRA021 is designed to work with the ISO 510 Amplifier System, see the Physiology Section I, however custom connectors are available upon request. The Transducer is supplied with instruction manual and calibration certificate. The TRA023 is designed to work with the ISO 510 Amplifier System, see the Physiology Section I, however custom connectors are available upon request. The Transducer is supplied with instruction manual and calibration certificate. Specifications Specifications Range -50 to 300 mmHg Sensitivity 4 µV/V/mmHg Bridge Resistance 350 W Excitation Voltage 5 to 10 VDC Volume Displacement 0.05 mm3/100 mmHg Total Volume 0.25 ml Weight 85 g Size 18 x 24 x 74 mm Order # Model PY2 76-0411 TRA021 J8 Range -50 to 300 mmHg Sensitivity 5 µV/V/mmHg Excitation Voltage 2 to 5 VDC Operating Life > 500 hrs Order # Model PY2 76-0326 TRA023 Product Disposable Research Pressure Transducer Product Reusable Research Pressure Transducer Harvard Apparatus • phone 508.893.8999 • toll free U.S. 800.272.2775 • fax 508.429.5732 • www.harvardapparatus.com transducers Electronic Pressure Calibrators The built-in pressure meter measures the set pressure accurately and indicates it in digital form. Since the generated pressure is identical at the built-in pressure meter and at the test object, the pressure measured by the test object corresponds exactly to the pressure indicated by the KAL 84. Electronic Pressure Calibrators Models with different pressure ranges are available. Each model has an application-specific range (range 1) and can be switched to a corresponding SI range (range 2) in Pascal (Pa) or Kilopascal (kPA). The calibrator KAL 84 is used for calibrating pressure sensors. It represents a combination of a pressure generator (hand pump) and a pressure meter with digital display. The instrument provides a simple means for testing and calibrating both pressure sensors and complete pressure measuring equipment. High accuracy and excellent reproducibility together with an especially rugged construction provide the unit with all the properties required for laboratory applications. After the unit has been switched on and connected to the pressure sensor to be calibrated (test object), the required pressure is set with the small hand-wheel. Measurement and calibration range for appropriate model (see table below) Linearity ±0.5% FS ±1 digit for mercury models, ±1% FS ±1 digit for water models Hysteresis 0.1% FS Overpressure Limit 200% FS for mercury models 500% FS for water models Response Time TE = 20 ms, time constant can be switched to 0.1 sec or 1 sec Analog Output 0 to 1 V for 100% nominal range, load resistance at least 2 kΩ Temperature Range: Nominal +10°C to +50°C Operating 0°C to +60°C Pressure Connections 6.5 mm OD for 5 mm ID tubing Power Supply 9 V rechargeable battery, mains adapter Dimensions, H x W x D 100 x 260 x 180 mm (3.9 x 10.2 x 7.1 in) Weight Approx. 3 kg (6.6 lb) Optional Certificate Linearity test certificate, DKD (German calibration service, see below) Order # Cardiovascular • Maintenance free precision pressure generation • 4 units available: – 0 to 200 mmHg – 0 to 300 mmHg – 0 to 20 mmH2O – 0 to 200 mmH2O • Calibration certificate on request Range transducers Specifications Product PY2 73-0977 Calibration Certificate with KAL84 Purchase PY2 73-2918 Recalibration of KAL84 with Certificate (Requires Return of Unit) Electronic Pressure Calibrators 115 VAC, 60 Hz 230 VAC, 50 Hz Model Liquid Range 1 Range 2 Used for Calibration of: PY2 73-0012 PY2 73-0013 KAL 84 H Mercury 0 to 199.9 mmHg 0 to 26.66 kPa Blood Pressure Transducers PY2 73-0014 PY2 73-0015 KAL 84 SH Mercury 0 to 300.0 mmHg 0 to 39.99 kPa Blood Pressure Transducers PY2 73-0016 PY2 73-0017 KAL 84 L Water 0 to 19.99 mmH2O 0 to 196.0 Pa Low-Range Differential Pressure Transducers PY2 73-0018 PY2 73-0019 KAL 84 M Water 0 to 199.9 mmH2O 0 to 1960 Pa Low-Range Differential Pressure Transducers Harvard Apparatus • phone 508.893.8999 • toll free U.S. 800.272.2775 • fax 508.429.5732 • www.harvardapparatus.com J9 transducers NEW Millar MPVS Ultra Pressure-Volume Systems MPVS Ultra Hardware transducers The MPVS Ultra simultaneously and continuously measures high-fidelity left ventricular pressure and relative volume from the intact beating hearts of animals ranging in size from transgenic mice to domestic livestock. Cardiovascular Using the MPVS Ultra, cardiovascular pressure and volume signals can be plotted against each other in real time, generating the characteristic pressure-volume (P-V) loops that are an excellent illustration of the cardiac cycle in normal or diseased conditions of the living heart. MPVS Ultra is the only complete solution for measuring real-time cardiovascular pressure and volume in small and large animal models with an industry-leading seven volume segments. Millar catheters and hardware integrate seamlessly with Harvard Apparatus Physiology systems to create a complete Cardiovascular Physiology solution. MPVS Ultra Components • MIKRO-Tip® P-V catheters • P-V signal conditioning hardware with innovative software-controlled user interface • PVAN Ultra™ data analysis software • Rho cuvette for volume calibration • Data acquisition system (Choose from available Harvard Apparatus DAQ systems in Physiology Section I) • Connection cables • Computer (not included) J10 2F Pressure-Volume Catheter, SPR-838 Features • Real-time pressure-volume measurement at the source • High-frequency response • No motion artifact or damping of pressure signal • Minimally invasive • Small and large animal capabilities • Software controlled user interface • Comprehensive, easy-to-use analysis software Applications • Baseline P-V loop analysis • Occlusion P-V loop analysis • Phenotyping gene manipulations • Cardiac hypertrophy • Cardiac failure • Cardiovascular remodeling • Toxicology • Pharmacology (rapid drug screening) • Cardiac resynchronization therapy • Surgical interventions • Ischemia/reperfusion studies ✐ NOTE: Please contact your local Harvard Apparatus Representative or our Technical Support Team to configure a system to your requirements. Harvard Apparatus • phone 508.893.8999 • toll free U.S. 800.272.2775 • fax 508.429.5732 • www.harvardapparatus.com transducers NEW Millar MPVS Ultra Pressure-Volume Systems (continued) 1.4F SPR-839 Enlargement of tips of Pressure-Volume Catheters Order # Product transducers 210F SPR-838 PY2 72-9739 MPVS Ultra Single Segment Unit with Control Interface Software PY2 72-9834 MPVS Ultra Upgrade (Converts Single Segment Unit to Multi Segment Unit) MPVS Ultra Multi Segment for all animal models PY2 72-9724 MPVS Ultra with Control Interface Software Accessories PY2 72-9835 Ultra Cable Pack 4 ft (CEC-4E PV Cable, PEC-4D) PY2 72-9727 Ultra Cable Pack 10 ft (CEC-10E PV Cable, PEC-10D) PY2 72-9728 BNC Cable Pack-PowerLab (10 BNC-BNC 9 in, 1 BNC-BNC 1 ft, 2 BNC-BNC 3 ft) PY2 72-9836 BNC Cable Pack-STD. (13 BNC-BNC 3 ft) PY2 72-9726 RHO CUVETTE w/ Well and Cable as one unit PY2 72-9725 PVAN Ultra SOFTWARE CD PY2 72-9837 EPC-10UT - ECG Cable 10 ft unterminated PY2 72-9838 CEC-4E - PV Extension Cable, 4 ft PY2 72-9826 PEC-4D - Pressure Extension Cable, Redel - Low Profile 4 ft PY2 72-9839 CEC-10E - PV Extension Cable, 10 ft PY2 72-9816 PEC-10D - Pressure Extension Cable - Low Profile 10 ft ✐ Cardiovascular MPVS Ultra Single Segment for Mouse & Rat use only NOTE: Please contact your local Harvard Apparatus Representative or our Technical Support Team to configure a system to your requirements. Harvard Apparatus • phone 508.893.8999 • toll free U.S. 800.272.2775 • fax 508.429.5732 • www.harvardapparatus.com J11 transducers NEW Millar MIKRO-Tip P-V Catheters MIKRO-Tip P-V catheters combine pressure sensors and electrodes for simultaneous high-fidelity pressure-volume measurements from a single instrument. Order # Model Product Single Segment Catheters - Mice, Rats PY2 72-9740 PVR-1030 1F, 4E 3.0 mm spacing, 4.5 cm, Non-repairable PY2 72-9722 PVR-1035 1F, 4E 3.5 mm spacing, 4.5 cm, Non-repairable PY2 72-9721 PVR-1045 1F, 4E 4.5 mm spacing, 4.5 cm, Non-repairable PY2 72-9723 SPR-839 1.4F, 4E 4.5 mm spacing, 4.5 cm PY2 72-9738 SPR-839 1.4F, 4E 4.5 mm spacing, 4.5 cm, NO REPAIR PY2 72-9741 SPR-853 1.4F, 4E, 4.0mm, TAPER PY2 72-9742 SPR-848 1.4F, 4E 4.5 mm spacing, Dual sensor, APICAL PY2 72-9743 SPR-864 1.4F, 4E 4.5 mm spacing, Dual sensor, CAROTID PY2 72-9744 SPR-847 1.4F, 4E 9.0 mm spacing, 15 cm PY2 72-9745 SPR-869 2F, 4E 6.0 mm spacing, 15 cm transducers Cardiovascular PY2 72-9745NR SPR-869 2F, 4E 6.0 mm spacing, 15 cm, NO REPAIR PY2 72-9736 SPR-838 2F, 4E 9.0 mm spacing, 15 cm PY2 72-9737 SPR-838 2F, 4E 9.0 mm spacing, 15 cm, NO REPAIR PY2 72-9746 SPR-878 2F, 4E 12.0 mm spacing, 15 cm PY2 72-9747 SPR-858 2F, 4E 14.0 mm spacing, 15 cm PY2 72-9748 SPR-901 2F 2P, 4E 9.0 mm spacing, 15 cm, CAROTID PY2 72-9749 SPR-902 2F 2P, 4E 9.0 mm spacing, 15 cm, APICAL 2F Multi Segment Catheters - Large Rats PY2 72-9750 SPR-931 2F, Single Field, 6E 3.0mm spacing, Straight, 12.5 cm PY2 72-9751 SPR-932 2F, Single Field, 8E 3.0mm spacing, Straight, 12.5 cm 3F Multi Segment Catheters - Rabbits/Cats PY2 72-9752 SPR-923-1 3F, Single Field, 10E 3.0mm spacing, Straight, 105 cm PY2 72-9753 SPR-923-3 3F, Single Field, 10E 4.5mm spacing, Straight, 105 cm PY2 72-9754 SPR-877 3F, 10E Dual Field 2.5 mm spacing, Straight, 120 cm PY2 72-9755 SPR-855 3F, 10E Dual Field 4.0 mm spacing, Straight, 120 cm PY2 72-9756 SPR-856 3F, 10E Single Field 4.5 mm spacing, Straight, 120 cm PY2 72-9757 SPR-889 3F, 10E Single Field 3.0 mm spacing, U-Tip, 80 cm PY2 72-9758 SPR-894 3F, 10E Dual Field 4.0 mm spacing, U-Tip, 80 cm PY2 72-9759 SPR-845 3F, 8E Single Field 3.0 mm spacing, U-Tip, 120 cm PY2 72-9760 SSD-1033 3F, 8E Single Field 4.3 mm spacing, U-Tip, 140 cm 5F Multi Segment PV Catheters - Dog/Pig/Sheep PY2 72-9761 SPR-550-2 5F, 12E Dual Field 9.0 mm spacing, Pigtail, 125 cm PY2 72-9762 SPR-550-5 5F, 12E Dual Field 7.0 mm spacing, Pigtail, 125 cm PY2 72-9763 SPR-550-7 5F, 12E Dual Field 10.0 mm spacing, Pigtail, 125 cm PY2 72-9764 SPR-550-8 5F, 10E Single Field 7.0 mm spacing, Pigtail, 125 cm PY2 72-9765 SPR-554-5 5F, 12E Dual Field, 7.0 mm spacing, Straight, 125 cm PY2 72-9766 SPR-554-11 5F, 10E Dual Field, 7.0 mm spacing, Straight, 125 cm PY2 72-9767 SPR-560-1 5F, 12E Dual Field, 7.0 mm spacing, Pigtail, 125 cm PY2 72-9729 SPR-562-1 6F 2P, 12E Dual Field 7.0 mm spacing, Pigtail 125 cm PY2 72-9769 SPR-570-2 7F, 12E Dual Field, 9 mm spacing, Pigtail 125 cm PY2 72-9770 SPR-570-7 7F, 12E Dual Field, 10 mm spacing, Pigtail 125 cm PY2 72-9771 SPR-570-9 7F, 8E Single Field, 8.5 mm spacing, Pigtail 125 cm PY2 72-9772 SPR-572-7 7F, 12E Dual Field, 10 mm spacing, Pigtail 125 cm RAT/MOUSE SELECTABLE SEGMENT - For use with MPVS-300/400 only J12 PY2 72-9768 SPR-819 1.4F, 6E, 9.0 mm/14.0 mm PY2 72-9773 SPR-866 1.4F, 6E, 4.0 mm/6.0 mm Harvard Apparatus • phone 508.893.8999 • toll free U.S. 800.272.2775 • fax 508.429.5732 • www.harvardapparatus.com transducers NEW Millar MIKRO-Tip and Ultra Miniature Pressure Catheters Millar pressure catheters continue to represent the gold-standard for high-fidelity pressure measurements for both systemic and intraventricular applications. 2F Pressure Catheter SPR-407 Order # Model Product Pressure Catheters SPR-671 PY2 72-9779NR SPR-671 PY2 72-9775 SPR-407 1F, Single pressure, 20 cm, Straight, Non-repairable 1.4F Single pressure,1.1F-2F body 15cm from tip, 65 cm 1.4F Single pressure,1.1F-2F body 15cm from tip, 65 cm, NO REPAIR 2F Sensor, 1.5F Body, Single Pressure, 140 cm, Straight PY2 72-9775NR SPR-407 2F Sensor, 1.5F Body, Single Pressure, 140 cm, Straight, NO REPAIR PY2 72-9776 SPR-513 2F Sensor, 1.5F body, 140 cm, Angled 5mm from tip PY2 72-9783 SPR-320 2F Single pressure, 140 cm, Straight PY2 72-9783NR SPR-320 2F Single pressure, 140 cm, Straight, NO REPAIR PY2 72-9774 SPR-249A 3F Single pressure, 60 cm, Straight PY2 72-9778 SPR-595 3F Single pressure, 60cm, Angled PY2 72-9780 SPR-882 3F Single pressure, 140 cm, Straight PY2 72-9784 SPR-330A 3F Single pressure, 130 cm, Straight PY2 72-9777 SPR-524 3.5F Single pressure, 100 cm, Straight, Non-repairable PY2 72-9785 SPR-340 4F Single pressure, 120 cm, Curved PY2 72-9786 SPR-340S 4F Single pressure, 120 cm, Straight PY2 72-9782 MPR-500 5F Single pressure, 70 cm, Non-repairable PY2 72-9787 SPR-350 5F Single pressure, 120 cm, Curved PY2 72-9788 SPR-350S 5F Single pressure, 120 cm, Straight PY2 72-9793 SPR-450 5F Single pressure w/ Lumen,120 cm, Curved PY2 72-9794 SPR-450S 5F Single pressure w/ Lumen,120 cm, Straight PY2 72-9789 SPR-360 6F Single pressure, 120 cm, Curved PY2 72-9790 SPR-360S 6F Single pressure, 120 cm, Straight PY2 72-9791 SPR-370 7F Single pressure, 120 cm, Curved PY2 72-9792 SPR-370S 7F Single pressure, 120 cm, Straight PY2 72-9795 SPR-470 7F Single pressure w/ Lumen,120 cm, Curved PY2 72-9796 SPR-471A 7F Single pressure, Injection lumen, 115cm, Straight PY2 72-9797 SPR-474A 7F Single pressure, Injection lumen, Pigtail, 120 cm, Straight PY2 72-9798 SPR-721 2.5F Dual pressure, 135 cm, Straight PY2 72-9799 SPR-780C 8F Dual sensor, Pigtail, 120 cm, Straight PY2 72-9800 SPR-784A 8.5F Dual sensor, Pigtail, 120 cm, Straight Harvard Apparatus • phone 508.893.8999 • toll free U.S. 800.272.2775 • fax 508.429.5732 • www.harvardapparatus.com transducers SPR-1000 PY2 72-9779 Cardiovascular PY2 72-9781 J13 transducers NEW Millar Electrophysiology Catheters and Adapter Cables Amplifier Cables and Adapters Millar Electrophsiology Catheters Adapters and cables are available to connect catheters directly to the range of Harvard Apparatus pressure amplifiers. Millar electrophysiology catheters utilize tried and true construction to provide a reliable and minimally invasive way to measure intra-cardiac electrical activity. Order # Adaptor cables are available to connect catheters directly to the range of Harvard Apparatus Biopotential amplifiers. Call for pricing and availability. Product PY2 72-9842 HEC-10C Pressure Catheter with Viking Connector to PLUGSYS TAM Amplifier PY2 72-9843 HEC-10D Pressure Catheter with Low Profile Connector to PLUGSYS TAM Amplifier Order # Model Product PY2 72-9801 EPR-800 1.1F, 8E Gold, 1.0 mm Spacing, 4.5 cm, Redel transducers Cardiovascular PY2 72-9734 AEC-10D Pressure Catheter with Low Profile Connector to ADInstruments Bridge Amp PY2 72-9802 EPR-801 PY2 72-9844 AEC-10C Pressure Catheter with Viking Connector to ADInstruments Bridge Amp 1.1F, 8E Gold, 1.0 mm Spacing, Injection Lumen, 4.5 cm, Redel PY2 72-9803 EPR-802 PY2 72-9810 TC-510 9pin D-sub Control Unit, Interface Cable Required 1.6F, 8E gold, 1.0 mm Spacing, 12.5 cm, Redel PY2 72-9804 EPE-3A PY2 72-9841 Cable, TC-510 to PLUGSYS TAM Amplifier 3 ft cable, Redel-Redel, Interfaces with STG Units PY2 72-9811 TEC-5C 5 ft Cable, Viking Connector to TC-510 Unit PY2 72-9805 STG-3004 PY2 72-9812 TEC-10C Unit 10 ft Cable, Viking Connector to TC-510 4 Channel Stimulation, 8 Amplification, 8 Analog Input PY2 72-9806 STG-3008 PY2 72-9813 TEC-10D 10 ft Cable, Low Profile Connector to TC-510 Unit 8 Channel Stimulation, 8 Amplification, 8 Analog Output PY2 72-9807 EP Grounding Kit Cable set PY2 72-9814 PCU-2000 CE marked, patient isolated, line powered dual & single pressure PY2 72-9808 EPC-5A Cable 5 ft Cable, Redel 14-pin connector PY2 72-9809 EPC-5UT Cable 5 ft Cable, Redel 14-pin connector unterminated PY2 72-9815 PEC-10C 10 ft Cable, Viking Connector to PCU-2000 Unit PY2 72-9816 PEC-10D 10 ft Cable, Low Profile Connector to PCU-2000 Unit PY2 72-9817 BNC-BNC Cable PY2 72-9818 BNC-Phono Adapter PY2 72-9819 SD-778 10 ft P-V Catheter Electrodes to CD Leycom Sigma 5 Unit PY2 72-9731 SD-797 Connects TC-510 to ADInstruments Bridge Amp ML110, 112, 118 PY2 72-9732 SD-810 Reversing Cable, Apical approach PV Catheters to CD Leycom ✐ J14 Model NOTE: Don’t see an adapter to your amplifier? Contact technical support for a custom adapter. Harvard Apparatus • phone 508.893.8999 • toll free U.S. 800.272.2775 • fax 508.429.5732 • www.harvardapparatus.com transducers View of the catheter: the catheter (blue) on the right of the handle has a length of 110cm and a diameter of 7F (2.33mm). At the end of the catheter the light blue 90° stearable part of the catheter is visible. The distal white end tip includes 4 electrodes. For intraventricular MAP recording For pacing Accurate Steerable unidirectional up to 90° curve This new combination catheter is used for in-vivo studies in anesthetized dogs or pigs. The handle allows to curve unidirectionaly up to 90° the steerable end of the catheter to place the tip optimally inside the ventricle on the heart wall. The two stimulation electrodes allow pacing and the recording electrodes to record the intraventricular MAP. Specifications Cardiovascular • • • • transducers NEW Combination Catheter MAP-Stimulation 7F View of the curved (unidirectional stearable catheter end. (the MAPand the Reference- electrode are visible Schematic representation of the distal tip. (shows also the coding colors to the cable connection) MAP Electrode Central, axial Ag/AgCl MAP-electrode, D=1.5 mm, protruding by 1mm (Yellow connecting line) Order # Reference Electrode Lateral Ag/AgCl Reference electrode, D=1 mm, 5 mm proximal to the tip (Blue connecting line) PY2 73-3872 Combination Catheter MAP-Stimulation 7F for in-vivo studies Stimulation Electrodes 2 lateral opposite Ag Stimulation electrodes, D=1 mm, 3 mm proximal to the tip (Green and Red connecting lines) Catheter Size 7F (2.33 mm, 0.091 in) Catheter Length 110 cm (43.31 in) Catheter Feature Stearable, 90° Curve, Unidirectional Connectors 2 mm Banana Male Connectors Cable Length 60 cm (23.62 in) Product PY2 73-3356 Input Cable with 2mm Sockets for BPA (for MAP electrodes) PY2 73-3985 Bipolar Connecting Cable 4mm banana male to 2mm socket, length 2m (for Stimulation electrodes) Harvard Apparatus • phone 508.893.8999 • toll free U.S. 800.272.2775 • fax 508.429.5732 • www.harvardapparatus.com J15