I
, D
T
C
The University of New Mexico Center for Molecular Discovery (UNMCMD) grand opening on October 5 th will display its capabilities and provide a tour of the labs at 700 Camino de
Salud, building 289. Please join us for the ribbon cutting ceremony at 11:00 am
with tours until
3:30 pm
. Parking will be available in the M Lot to the north of IDTC (see map next page) .
The UNMCMD is a drug discovery center for academic and industry collaborations that has been funded by the
NIH for more than 10 years. It is part of the new Innovation, Discovery, and Training Complex. UNMCMD is affiliated with the Department of Pathology Cytometry Division, Department of Internal Medicine Translational
Informatics Division, the UNM Clinical and Translational Science Center, and the UNM Cancer Center. Pathology faculty members include Larry Sklar, Bruce Edwards, Alexandre Chigaev, George Tegos, and Yang Wu.
UNMCMD has a full range of drug discovery capabilities in: 1) Target Development; 2) High Throughput Screening; and 3) Cheminformatics. UNMCMD invented the high throughput flow cytometry platform and performs multiplex and multiparameter screens on cellular and molecular targets in both 384 and 1536 well format. Equipment includes more than 20 flow cytometers, the Synergy H4 plate reader, a range of sample preparation capabilities as well as Beckman-Coulter and Agilent automation systems which permit complex sample handling for adherent and suspended cell mixtures.
UNMCMD applies its drug discovery expertise to the UNM Signature Programs in Cancer, Cardiovascular Disease, Childhood Health, Environmental Health, Global Health, Immunity, Infectious Disease, Metabolic Disease, and Neurological Disease. It is co-located in IDTC with the Center for Digestive Disease Research and the Department of Emergency Medicine.
Drug Discovery Targets include G protein-coupled receptors, integrins and adhesion molecules, drug resistance transporters, stem cells, personalized medicine, pathogens, host-pathogen interactions, and protein-protein as well as protein-small interactions.
Informatics expertise include state-of-the-art, innovative tools for ligand-based and structure-based virtual screening; unique tools for post-HTS analyses, clustering and in silico profiling; high performance tools for bioinformatics analyses; unique data archiving and data mining capabilities.
UNM’s advance screening technologies have led to the discovery of drug candidates including:
• Ras-related GTPases as Targets of Small Molecule Inhibitors
• Rab7 GTPase as Small Molecule Targets
• Novel Specific Inhibitor of Cdc42 GTPase for Cell Biology and Human Disease
• Method for Integrin Ligand Discovery
• Bead-based Detection of Glutathione and GST-fusion Protein Multiplexing Using High Site Density
Glutathione Beads
• Compounds for Drug Therapy that Target ABCG2

Innovation, Discovery and Training Complex (IDTC)
700 Camino de Salud, Building 289
Center for Molecular Discovery
We are in the old OMI/TriServices Building which is to the west of Family Practice. Please enter through the north door. Go straight down the hall and turn left at the admin desk. The conference room is on the left.
Phone: 505-925-4752
Tucke r Ave
.
M Lot
Parking
Novitski
Hall
M Lot
Parking
Domenici
Center
Marble Ave.
IDTC
FPC
HSLIC
HSSB
CON/COP
UNMPC
Ya le lv
B d.
Camino
de Salu d
CRF BRF
BMSB
Patient
Parking
UNM Hospital
Lom as Blv d.
Barbara & Bill
Richardson
Pavilion
ACC
Employee Parking
Campus Blvd.