CEM 262 — Quantitative Analysis — Fall 2016
Syllabus and Course Calendar
Instructor:
Office Hours:
Dr. Thomas P. Carter
Room 383A Chemistry (third floor, down the blue hallway)
Phone: 517-353-1108
Email: carter@chemistry.msu.edu or cartert@msu.edu
After class, drop by anytime, or by mutually agreed appointment.
Course Web Site:
http://www.chemistry.msu.edu/courses/cem262 (I post everything here).
Lectures:
Mondays and Wednesdays, 8:00 AM – 8:50 AM, Room 101 Biochemistry
Lab Classroom:
Recitation
classrooms:
Room 304 Chemistry
Section 001: 127 Chemistry
Section 002: 126 Chemistry
Section 003: 085 Chemistry
Section 004: 085 Chemistry
Section 005: 126 Chemistry
Section 006: 183 Chemistry
Attendance is required in lecture, recitation, and lab.
TAs:
Andre Castiaux (castiaux@chemistry.msu.edu), sections 3 & 6
Andrew Heller (hellera2@chemistry.msu.edu), sections 1 & 5
Hannah Mize (mizehann@chemistry.msu.edu), sections 2 & 4
Required Texts
Exploring Chemical Analysis, 5th Edition, Daniel C. Harris, W.H. Freeman and Company, 2013
CEM 262 Quantitative Chemical Analysis Laboratory Manual 2016-2017 (Downloadable ONLY from the LON-CAPA
website: http://lon-capa.msu.edu/)
Required Materials
(1) Basic scientific calculator (with the capability of performing base-10 logarithms)
(2) Laboratory notebook with numbered, bound pages (an inexpensive ~$3 composition notebook works well,
lined or quad-ruled, with the pages hand-numbered prior to coming to lab)
(3) Safety goggles (MUST be splash proof, meeting OSHA-ANSI 279.1-1979 specifications)
Course Grading
The course is graded on what is very close to a straight scale. I reserve the right to alter the scale if I deem it
necessary, but under no circumstances will these thresholds be raised making it more difficult for you to achieve a
good grade. Your overall course grade will be calculated according to the following breakdown:
Experiments
Percent
Score
90–100%
85–89%
80–84%
75–79%
70–74%
65–69%
60–64%
< 60%
50%
Laboratory Performance
5%
Recitation Performance
5%
Homework (LON-CAPA)
5%
Hour Exam 1
10%
Hour Exam 2
10%
Final Exam
15%
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Course
Grade
4.0
3.5
3.0
2.5
2.0
1.5
1.0
0.0
CEM 262 — Quantitative Analysis — Fall 2016
Syllabus and Course Calendar
TENTATIVE Lecture Schedule
Lecture
Date
Assigned reading
1
August 31
Chapters 1-1 — 1-4
Lab manual thru p. 12
Subject
Course operation; laboratory basics;
review of volumetrics
September 5 (Labor Day) — NO LECTURE
2
September 7
Chapters 6-1 — 6-3,
10-4 — 10-6, 3-1 — 3-3
3
September 12
Chapter 4-1 — 4-3
4
September 14
Chapters 3-3, 4-2, 4-4
5
September 19
All of Chapter 8,
Chapter 10-1 — 10-3
6
September 21
Chapter 1-5
Chemical equilibrium and activity (introduction/review)
7
September 26
Chapter 8-3 — 8-7
Solution chemistry of acids, bases and salts – Ka, Kb, Kw
8
September 28
Chapter 9-1 — 9-5
Buffers, The Henderson-Hasselbalch equation
9
October 3
Lab manual
Ka and equivalent weight for a weak acid (Expt. 2)
10
October 5
Chapter 9-6
Titration curves and acid-base indicators
11
October 10
Chapter 11-1 — 11-3
Titrimetry basics; sig figs; characterization of errors
Calculation of statistical values and tests
Accuracy and precision; random, systematic and gross errors;
Grubbs test and Student’s t-test.
Aqueous solution chemistry; strong and weak acids/bases
Polyfunctional acids and bases; alpha values; amphiprotic salts
Exam 1
October 12
12
October 17
Chapter 12-1 — 12-2
Electrolyte effects; activity, ionic strength
13
October 19
Chapter 6-4
14
October 24
Chapter 7-1 — 7-3
15
October 26
16
October 31
Chapter 13
Complexation and metal-ion titrations
17
November 2
Lab manual
EDTA equilibria and calculations (Expt. 4)
18
November 7
19
November 9
Chapter 16-3
Oxidation-reduction reactions (balancing) and redox titrations
20
November 14
Lab manual
Iodometric titrations (Expt. 5)
Sparingly soluble salts; Ksp
Gravimetric methods
Equilibrium calculations
Electroanalytical chemistry
Exam 2
November 16
21
November 21
Chapters 18,
19-1, 19-2, 19-4
22
November 23
Lab manual
Introduction to spectroscopy; absorbance and transmittance;
Beer’s law
Standard addition, external standards; (Expt. 6)
THANKSGIVING BREAK — No labs/recitations for anyone this week
Calibration curves, linear least-squares regression; solving multicomponent absorbance of mixtures
23
November 28
Chapter 4-5 — 4-6
24
November 30
Lab manual
25
December 5
Sensitivity and accuracy of spectroscopic measurements
26
December 7
Review ?
Expt. 7
Tuesday December 13, 2016 7:45-9:45 a.m.
Final Examination, 101 Biochemistry
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CEM 262 — Quantitative Analysis — Fall 2016
Syllabus and Course Calendar
Experiments (50%)
Since this is a quantitative chemical analysis course, the grade for each experiment will be based almost entirely
on the accuracy of your results. Important keys to your success are your use of proper laboratory techniques and
careful planning. Labs are considered timed practical exams, and as such, you should work alone and not provide
to, or accept any data or results from, anyone else. You will submit your lab results on a “report card” (provided
by your TA) no later than the beginning of your recitation period on the due date for your Section (see the table
below). No lab results will be accepted other than by submitting the normal “report card” to your TA or to me. NO
E-MAIL SUBMISSIONS WILL BE ACCEPTED.
Experiments 1, 3, 4, and 5 are worth a maximum of 100 points each. Experiments 2, 6, and 7 are worth a maximum
of 110 points each, because properly formatted graphs must be prepared with spreadsheet/graphing software
(e.g. Microsoft Excel or Synergy’s KaleidaGraph, etc.) and submitted with the report cards for these experiments.
In this way, the maximum number of points obtainable for all 7 experiments is 730 points.
You may redo an experiment as many times as you like in the allotted time, but your grade will be determined by
the LAST results you submitted, NOT by your best results. Each time you redo an experiment you must obtain a
different unknown from your TA.
Important: Once the laboratory course has started, you perform the 7 experiments at your own pace. The
Guideline Dates indicated in the table below show the latest date the experiments should be started, and if these
guideline dates are followed, you should have no problem in completing the labs in the time allotted, though
not leaving any time for redoing any experiments. The Due Dates indicated for the results for the individual
experiments are not flexible. Any results turned in after the due date will be penalized 10 points. As noted above,
and if time allows, experiments may be repeated in an effort to improve your grade, and results from the re-done
experiments do not have to follow the timetable indicated above, but if they are turned in after the Due Date, the
10-point penalty applies. Also, no lab results will be accepted after the beginning of the Final Exam, Tuesday,
12/13/2016. Remember: your last results determine your grade, not your best results. Of course, you may turn in
results early. It is wise to try to get AHEAD of the schedule in the table below.
During your lab session, you must be properly attired, have appropriate safety goggles, and
you must have your laboratory notebook, or you will not be allowed to work in the lab.
Labs begin the first week of class. The due dates for the experiments are given by the week in which they are due
per the table below:
Week #
Week starting on
Monday:
Guideline Dates for
experiment start
1
August 31
NO LABS FOR ANYONE
2
September 5
Check-in/safety training,
Start Experiment 1
3
September 12
4
September 19
5
September 26
6
October 3
Start Experiment 3
Start Experiment 2
Experiment 1
7
October 10
Start Experiment 4
8
October 17
Start Experiment 5
9
October 24
10
October 31
11
November 7
12
November 14
13
November 21
14
November 28
15
December 5
Due Dates for
experiment results
Experiment 2
Experiment 3
Start Experiment 6
Experiment 4
Start Experiment 7
Experiment 5
Thanksgiving Week — NO LABS FOR ANYONE
Experiment 6
Exp 7. and any late lab results are due at beginning of the Final Exam, Tuesday Dec. 13th
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CEM 262 — Quantitative Analysis — Fall 2016
Syllabus and Course Calendar
Attendance and Make-ups
You may attend only the lab session to which you are enrolled. Exceptions may be made in the case of excused
absences, but only with prior approval from me – not your TA. Be prepared to provide evidence to obtain an
excused absence make-up for a lab or an exam: concrete evidence of a visit to an M.D. or clinic, court appearance,
etc. If you are granted a make-up, schedule it, and then miss it, you will need to provide another excuse.
Absences requested for grief-related reasons must follow the MSU Grief Absence Policy.
It is the responsibility of students who plan to be absent from class due to religious observances, varsity sports
participation, school-related trips, or other valid reasons, to make arrangements in advance with the instructor.
If a make-up exam is granted, the instructor retains the right to determine the content of the exam and the conditions
of administration, giving due consideration to equitable treatment.
Laboratory performance/laboratory notebook (5%)
Five percent (5%) of your course grade will be based upon your laboratory/notebook performance as assessed by
your TA. Your use of proper safety practices, care of equipment such as balances and pH meters, your ability to
work independently, willingness to understand and follow instructions, and proper use and maintenance of your
laboratory notebook are among the things that will be considered in the assessment of this portion of your grade.
Guidelines for your notebook (including an example lab entry to use as a model) are provided in the beginning
of the lab manual. Unannounced notebook inspections will be conducted by your TAs throughout the term. Any
scraps of paper containing laboratory data may be confiscated any time they are discovered. It is imperative to
ALWAYS properly record all of your data directly into your lab notebook.
Homework (5%)
Homework assignments and distribution of the Lab Manual will be done through the LON-CAPA system which
is accessed over the Web at http://lon-capa.msu.edu. Log on to the LON-CAPA system using your MSUNetID.
Assignments are given periodically, each of which include several problems to work. You can make as many as
99 attempts to solve each problem; grading is based only on whether you answered the problem correctly and
the number of attempts it took you makes no difference. The goal is to require you to get practiced in working
problems and thereby improve your problem solving skills.
Recitations (5%)
YOUR ATTENDANCE IN RECITATION IS VERY IMPORTANT TO YOUR SUCCESS IN THIS COURSE. Your TA will
be demonstrating proper lab techniques, providing insight into the best strategy for preparing and performing
experiments, and discussing the calculations involved in reporting your experimental results. TAs will also answer
questions about the concepts presented in lectures and homework problems. Lab report cards will be turned in
at the BEGINNING of recitation on or before the due date or they will be marked “late”, and receive the 10-point
penalty. There will be in-class assignments and quizzes to facilitate the understanding of lecture topics. Your
attendance and, most importantly, participation & performance in recitation will be evaluated by your TA and
considered as 5% of your grade.
Hour Examinations (20%, combined)
There will be two in-class one-hour examinations, on Wednesday, October 12, 2016 and Wednesday, November
16, 2016. Each of these examinations will test the course material which has been covered up to that point,
and each will be worth 10% of your final grade. No cellphones/tablets/computers, etc., may be used during an
examination, only a dedicated calculator.
Final Examination (15%)
The Final Exam will be on Tuesday, December 13, 2016 at 7:45–9:45 AM in Room 101 Biochemistry, and will be a
comprehensive examination on all the material (lectures and experiments) covered throughout the semester. It is
be worth 15% of your final grade.
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