Guilhem Chalancon
Trinity College, CB2 1TQ, Cambridge, UK
guilhem.chalancon@gmail.com
(44) - 741 460 5098
Dat a sci ent i st and syst em s bi ol ogi st
Experience
Data Mining & Statistical Inference
Strong computational, statistical and analytical
skills ∙ Ability to design and apply complex
frameworks with the aim to derive simple,
quantitative or qualitative information ∙ Proved
capacity to adapt methods from various fields
(strategic management, marketing, engineering,
ecology) to biological problems.
Education
Communication & Knowledge
representation
Speaker and poster presenter in international
conferences ∙ Produced >8 research publications
in high impact scientific journals (inc. Science) ∙
Advanced skills in scientific illustration, data
visualisation and public presentations.
Project Management & Leadership
Managed research projects, both in teams or
autonomously ∙ Founded an open data analysis
group for Gates Cambridge scholars ∙ During 2
years, presided a national association focused on
careers in bioinformatics ∙ Took part in various
society councils and boards ∙ Reviewed >12
research manuscripts for academic journals
including Nature journals and Science.
Gates Cambridge Scholar, University of Cambridge
Since Oct. 2011
PhD in Computational Biology
I work at the MRC Laboratory of Molecular Biology, where I search for molecular determinants of cell-to-cell variability in gene expression. In the
course of my PhD, I have become an expert in R and in statistical analysis of network data, machine learning, clustering, structural equation modelling
and regression analyses. As a Gates Cambridge scholar, I also enjoy a fantastic interdisciplinary intellectual environment.
École Normale Supérieure (Cachan, France).
2007-2011
MS in Systems & Synthetic Biology (high honours)
BA in Molecular and Cell Biology (honours)
15 "normaliens" are admitted every year in biology at the ENS Cachan (out of ~1,000 candidates already selected in the CPGE cycle), which ranks in the
top 3 of French Grandes Écoles in science. Upon admission, students are entitled a 4-year merit-based maintenance.
Sainte Geneviève (Versailles, France)
2005-2007
Preparation to French "Grande Écoles" (CPGE)
Sainte-Geneviève is renowned for being extremely selective and having the highest success rates at the entrance exams for the most selective French
engineering and science schools. The top 4% of French high school students enroll in the nationwide CPGE system, but only ~300 of them get admitted
at Sainte-Genevieve every year.
Technical
skills
Academic
activities
Statistics (R Statistical package)
Data visualisation (R, ggplot2, d3.js, Illustrator, Powerpoint)
Programming (Perl, Shell, Sun Grid Engine, Git)
Database management (MySQL, XML)
Web design (HTML5, CSS, JavaScript)
OS (Mac OSX, Windows, Linux)
Visited laboratories
MRC Laboratory of Molecular Biology, Cambridge, UK (2009-2010; 2010-2011; 2011-present), Marie Curie Research Institute, Oxted, UK
(2009-2010), Institut Curie, Paris, France (2008-2009; 2009-2010).
Most significant awards
Gates Cambridge Scholarship (2011-2014; awarded to 90 out of >7,000 applicants admitted to Cambridge), Knox Trinity Studentship (20112014; Awarded to 2 French candidates admitted at Trinity college), Eleve Normalien (2007-2011; Selected students are awarded by the French
ministry of Education the status of civil servant during the 4 years of their schooling at ENS).
Communications in international conferences (selection)
Quantitative Methods in Gene Regulation (Dec. 2013, Cambridge, UK)
Single Cell Genomics (Oct. 2013, Rehovot, Israel)
PTMs and Cell Signalling (Dec. 2012, Copenhagen, Denmark)
EMBO PhD Symposium (Nov. 2012, Heidelberg, Germany)
EMBO Systems Biology sectorial meeting (Oct. 2011, Heidelberg, Germany)
EMBO Meeting (Sep. 2010, Barcelona, Spain)
Cold Spring Harbor conference on Systems Biology (Aug. 2010, Hinxton, UK)
Intelligent Systems for Molecular Biology (Jul. 2010, Boston, USA)
Systems Biochemistry conference (Mar. 2010, York, UK)
Publications
: articles for which I am a corresponding author.
: publications featured in other journals.
Research articles (2) in refereed international journals:
Tissue-specific splicing of unstructured segments that embed interaction motifs rewires protein interaction networks
Buljan M, Chalancon G,Eustermann S, Wagner G, Fuxreiter M, Bateman A, Babu MM
Molecular Cell, Jun 2012; 46(6):871­83. — Impact Factor: 14.20
Rab and actomyosin-dependent fission of transport vesicles at the Golgi complex.
Miserey-Lenkei S, Chalancon G, Bardin S, Formstecher E, Goud B, Echard A
Nature Cell Biology, Jul 2010; 12(7):645­54 — Impact Factor: 19.48
Review articles (2) in refereed international journals:
Alternatively-splicing of intrinsically disordered regions and rewiring of protein interactions.
Buljan M, Chalancon G, Dunker K, Bateman A, Balaji S, Fuxreiter M, Babu MM
Current Opinion in Structural Biology, 2013; 23:1­8 — Impact Factor: 9.48
Interplay between gene expression noise and regulatory network architecture.
Chalancon G, Ravarani CN, Balaji S, Martinez-Arias A, Jothi R, Babu MM
Trends in Genetics, 2012; 4(11):2618­2630 — Impact Factor: 13.36
Perspective articles (3) in refereed international journals:
Cell Biology. Reconfiguring regulation.
Chalancon G, Kruse K, Babu MM Science, Mar 2012; 335(6072):1050­1 — Impact Factor: 31.20
PLoS Computational Biology conference postcards from ISMB 2010.
Chalancon G, Kosloff M, Osmanbeyoglu HU, Saraswathi S PLoS Computational Biology, Nov 2010; 6(11):e1002000 — Impact Factor: 5.21
Nanobiotechnology: scaling up synthetic gene circuits.
Chalancon G & Babu MM
Nature Nanotechnology, Sep 2010; 5(9):631­3 — Impact Factor: 27.27
Book chapters (3):
Metabolic networks: structure and dynamics.
Chalancon G, Kruse K, Babu MM
In 'Encyclopaedia of Systems Biology', Dubitzky W, Wolkenhauer O, Cho K­H & Yokota H (Eds), Springer (New York) (2013)
Metabolic networks and their applications.
Kruse K, Chalancon G, Babu MM
In 'Encyclopaedia of Systems Biology', Dubitzky W, Wolkenhauer O, Cho K­H & Yokota H (Eds), Springer (New York) (2013)
Structure and evolution of transcriptional regulatory networks.
Chalancon G & Babu MM
In 'Bacterial Stress Responses' (2nd ed.), Storz G & Hengge R (Eds), ASM Press, pp. 93­118 (2011)
Reviewed publications for EMBO Journal (1), Genome Biology (1), Genome Research (1), PLoS Computational Biology (1), Molecular Biosystems (2),
Molecular Systems Biology (1), Nature Genetics (1), Nature Nanotechnology (1), Nuclear Acid Research (5), and Integrative Biology (1).
Other
activities
President of "JeBiF", a national association for young bioinformaticians (2010-2012);
Education representative, MRC-LMB (2012-)
Fundraising and education committees, ISCB Student Council (2010);
Communication officer of "CNS Conseil", a student consulting team at ENS Cachan (2007-2009)
— Additional information and contact details:
guilhem.chalancon@gmail.com |
guilhem.chalancon |
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