Guilhem Chalancon
Trinity College, CB2 1TQ, Cambridge, UK
guilhem.chalancon@gmail.com
(44) - 741 460 5098
Dat a sci ent i st and syst em s bi ol ogi st
Experience
Data Mining & Statistical Inference
Strong computational, statistical and analytical
skills · Ability to think, design, and apply
complex frameworks with the aim to derive
simple, quantitative or qualitative information ·
Proved capacity to adapt methods used in
various fields (strategic management,
marketing, engineering, ecology) to biological
problems.
Technical
Education
Communication & Knowledge
representation
Speaker and poster presenter in international
conferences · Produced >7 research publications
in very high impact scientific journals (inc.
Science) · Advanced skills in scientific
illustration, data visualisation and public
presentations.
Project Management & Leadership
Managed multiple research projects both in
teams and autonomously · Funded an open data
analysis group for Gates Cambridge scholars ·
During 2 years, presided a national association
focused on careers in bioinformatics · Took part
in various society councils and boards · Reviewed
>12 research manuscripts for journals including
Nature journals and Science.
Statistics (R Statistical package)
Data visualisation (ggplot2, d3.js, Illustrator, Powerpoint)
Programming (Perl, Shell, Sun Grid Engine, Git)
Database (MySQL, XML)
Web design (HTML5, CSS, JavaScript)
OS (Mac OSX, Windows 7, Linux)
Gates Cambridge Scholar, University of Cambridge
Since Oct. 2011
PhD in systems biology
I work at the MRC Laboratory of Molecular Biology, where I search for molecular determinants of cell­to­cell variability in gene expression. In the
course of my PhD, I have become an expert in R and in statistical analysis of network data, machine learning, clustering, structural equation modelling
and regression analyses. As a Gates Cambridge scholar, I also enjoy a fantastic interdisciplinary intellectual environment.
École Normale Supérieure (Cachan, France).
2007­2011
MS in Systems & Synthetic Biology (high honours)
BA in Molecular and Cell Biology (honours)
15 "normaliens" are admitted every year in biology at the ENS Cachan (out of ~1,000 candidates already selected in the CPGE cycle), which ranks in the
top 3 of French grandes écoles in science. Upon admission, students are entitled a 4­year merit­based maintenance.
Sainte Geneviève (Versailles, France)
2005­2007
Preparation to french "grande écoles" (CPGE)
Sainte­Geneviève is renowned for being extremely selective and having the highest success rates at the entrance exams for the most selective french
engineering and science schools. The top 4% of french high school students enroll in the nationwide CPGE system, but only ~300 of them get admitted
at Sainte­Genevieve every year.
Research
Visited laboratories
MRC Laboratory of Molecular Biology, Cambridge, UK (2009­2010; 2010­2011; 2011­present), Marie Curie Research Institute, Oxted, UK
(2009­2010), Institut Curie, Paris, France (2008­2009; 2009­2010).
Most significant awards
Gates Cambridge Scholarship (2011­2014; awarded to 90 out of >7,000 applicants admitted to Cambridge), Knox Trinity Studentship (2011­
2014; Awarded to 2 French candidates admitted at Trinity college), Eleve Normalien (2007­2011; Selected students are awarded by the French
ministry of Education the status of civil servant during the 4 years of their schooling at ENS).
Communications in international conferences (selection)
PTMs and Cell Signalling, Copenhagen (2012)
EMBO PhD Symposium, Heidelberg (2012)
EMBO Meeting, Barcelona (2010)
EMBO Systems Biology sectorial meeting, Heidelberg (2011)
Cold Spring Harbor conference on Systems Biology, Hinxton (2010)
Intelligent Systems for Molecular Biology, Boston (2010)
Systems Biochemistry conference, York (2010)
Publications
: articles for which I am a corresponding author. : publications featured in other journals.
Research articles (2) in refereed international journals:
Tissue­specific splicing of unstructured segments that embed interaction motifs rewires protein interaction networks
Buljan M, Chalancon G,Eustermann S, Wagner G, Fuxreiter M, Bateman A, Babu MM Molecular Cell, Jun 2012; 46(6):871­83. — Impact Factor: 14.20
Rab and actomyosin­dependent fission of transport vesicles at the Golgi complex.
Miserey­Lenkei S, Chalancon G, Bardin S, Formstecher E, Goud B, Echard A Nature Cell Biology, Jul 2010; 12(7):645­54 — Impact Factor: 19.48
Review articles (2) in refereed international journals:
Alternatively­spliced disordered regions and rewiring of protein interactions.
Buljan M, Chalancon G, Dunker K, Bateman A, Balaji S, Fuxreiter M, Babu MM
Current Opinion in Structural Biology, 2013; in press — Impact Factor: 9.48
Interplay between gene expression noise and regulatory network architecture.
Chalancon G, Ravarani CN, Balaji S, Martinez­Arias A, Jothi R, Babu MM Trends in Genetics, 2012; 4(11):2618­2630 — Impact Factor: 13.36
Perspective articles (3) in refereed international journals:
Cell Biology. Reconfiguring regulation.
Chalancon G, Kruse K, Babu MM Science, Mar 2012; 335(6072):1050­1 — Impact Factor: 31.20
PLoS Computational Biology conference postcards from ISMB 2010.
Chalancon G, Kosloff M, Osmanbeyoglu HU, Saraswathi S PLoS Computational Biology, Nov 2010; 6(11):e1002000 — Impact Factor: 5.21
Nanobiotechnology: scaling up synthetic gene circuits.
Chalancon G & Babu MM Nature Nanotechnology, Sep 2010; 5(9):631­3 — Impact Factor: 27.27
Book chapters (3):
Metabolic networks: structure and dynamics.
Chalancon G, Kruse K, Babu MM
In 'Encyclopaedia of Systems Biology', Dubitzky W, Wolkenhauer O, Cho K­H & Yokota H (Eds), Springer (New York) (2013)
Metabolic networks and their applications.
Kruse K, Chalancon G, Babu MM
In 'Encyclopaedia of Systems Biology', Dubitzky W, Wolkenhauer O, Cho K­H & Yokota H (Eds), Springer (New York) (2013)
Structure and evolution of transcriptional regulatory networks.
Chalancon G & Babu MM In 'Bacterial Stress Responses' (2nd ed.), Storz G & Hengge R (Eds), ASM Press, pp. 93­118 (2011)
Reviewed publications for EMBO Journal (1), Genome Biology (1), Genome Research (1), PLoS Computational Biology (1), Molecular Biosystems (2),
Molecular Systems Biology(1), Nature Genetics (1), Nature Nanotechnology (1), Nuclear Acid Research (3), and Integrative Biology (1).
Service
President of "JeBiF", a national association for young bioinformaticians (2010­2012);
Education representative, MRC­LMB (2012­)
Fundraising and education committees, ISCB Student Council (2010);
Communication officer of "CNS Conseil", a student consulting team at ENS Cachan (2007­2009)
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