Title (en)
Immunoassay for cyclopropylindole based synthetic cannabinoids, metabolites and derivatives thereof
Title (de)
Immunoassay für cyclopropylindolbasierte synthetische Cannabinoide, Metabolite und Derivate davon
Title (fr)
Dosage immunologique de cannabinoïdes synthétiques à base de cyclopropylindole, leurs métabolites et dérivés
Publication
EP 2781527 A1 20140924 (EN)
Application
EP 14160047 A 20140314
Priority
GB 201305061 A 20130320
Abstract (en)
The invention relates to the detection and quantification of cyclopropylindole based synthetic cannabinoids UR-144 and XLR-11 by providing
antobodies based on novel immunogens. These antobodies can be incorporated into methods and kits for the detection of UR-144, XLR-11 and
metabolites or derivatives thereof.
Inventor
• BENCHIKH ELOUARD (GB)
• FITZGERALD PETER (GB)
• LOWRY PHILIP (GB)
• MCCONNELL IVAN (GB)
Applicant
RANDOX LAB LTD (GB)
IPC 8 full level (invention and additional information)
C07K 16/44 (2006.01); G01N 33/94 (2006.01)
CPC (invention and additional information)
C07K 16/44 (2013.01); G01N 33/948 (2013.01); C07K 2317/33 (2013.01)
Citation (search report)
• [DY] EP 2487155 A1 20120815 - RANDOX LAB LTD [GB]
• [Y] US 2007037801 A1 20070215 - FROST JENNIFER M [US], et al
• [Y] VADIM SHEVYRIN ET AL: "Identification and analytical properties of new synthetic cannabimimetics bearing 2,2,3,3tetramethylcyclopropanecarbonyl moiety", FORENSIC SCIENCE INTERNATIONAL, vol. 226, no. 1-3, 1 March 2013 (2013-03-01),
pages 62 - 73, XP055123107, ISSN: 0379-0738, DOI: 10.1016/j.forsciint.2012.12.009
• [Y] HYEYOUNG CHOI ET AL: "Identification of (1-pentylindol-3-yl)-(2,2,3,3-tetramethylcyclopropyl)methanone and its 5-pentyl
fluorinated analog in herbal incense seized for drug trafficking", FORENSIC TOXICOLOGY, SPRINGER-VERLAG, TO, vol. 31, no.
1, 5 November 2012 (2012-11-05), pages 86 - 92, XP035167338, ISSN: 1860-8973, DOI: 10.1007/S11419-012-0170-5
• [DY] TIM SOBOLEVSKY ET AL: "Detection of urinary metabolites of AM-2201 and UR-144, two novel synthetic cannabinoids",
DRUG TESTING AND ANALYSIS, vol. 4, no. 10, 5 October 2012 (2012-10-05), pages 745 - 753, XP055123098, ISSN: 1942-7603,
DOI: 10.1002/dta.1418
• [Y] BARRY K LOGAN ET AL: "Technical Bulletin: NMS Labs test for JWH-018, JWH-019, JWH-073, JWH-250 and AM-2201
Primary Monohydroxy Metabolites in Human Urine", NMS LABS, 1 January 2011 (2011-01-01), XP055038739, Retrieved from
the Internet <URL:http://toxwiki.wikispaces.com/file/view/JWH_metabolites_II_Technical_Bulletin_vers_1.1.pdf> [retrieved on
20120920]
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
EPO simple patent family
EP 2781527 A1 20140924; GB 201305061 D0 20130501; US 2014287441 A1 20140925; US 9079964 B2 20150714
INPADOC legal status
2016-06-15 [INTG] ANNOUNCEMENT OF INTENTION TO GRANT
- Effective date : 20160518
2015-10-28 [17Q] FIRST EXAMINATION REPORT
- Effective date : 20150924
2015-04-29 [R17P] REQUEST FOR EXAMINATION FILED (CORRECTION)
- Effective date : 20150324
2015-04-29 [RBV] DESIGNATED CONTRACTING STATES (CORRECTION):
- Designated State(s) : AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL
PT RO RS SE SI SK SM TR
2014-09-24 [17P] REQUEST FOR EXAMINATION FILED
- Effective date : 20140314
2014-09-24 [AK] DESIGNATED CONTRACTING STATES:
- Kind Code of Ref Document : A1
- Designated State(s) : AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL
PT RO RS SE SI SK SM TR
2014-09-24 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO
- Countries concerned : BA ME