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LE Magazine September 2008
Dr. Mehmet Oz: Global Medicine
By Sue Kovach
Changing the way millions of people actively incorporate preventive health into their lives has
become a daily practice for Dr. Mehmet Oz. As one of the world’s most accomplished cardiac
surgeons, Dr. Oz is taking life-saving medicine beyond the operating room. Now, in an effort to
reinvent medicine on a global level, he has taken his visionary medical knowledge to every
conceivable form of media to teach people how to use natural methods to live longer, reduce stress,
and avoid the killers of heart disease and cancer.
A quick Google search reveals over 795,000 entries for Dr. Oz. On any given day, he can be heard
on XM Satellite Radio, seen on Oprah or Good Morning America or read in Esquire magazine or in
any of his bestselling YOU books. Everywhere one looks, there is Dr. Oz patiently instructing all of
us—both patients and doctors—on a new kind of medicine that begins with taking an enlightened
approach to preventing life-robbing diseases. Dr. Oz is at the forefront of an international revolution
in health and medicine.
Yet despite the immense media presence, Dr. Oz remains first and foremost a dedicated,
hardworking physician, a rolls-up-his-sleeves cardiac surgeon who is at the top of his field and
performs more than 250 surgeries annually. In addition to all of this, he has time to develop new lifesaving techniques.
Dr. Oz is director of the Heart Institute at New York Presbyterian/Columbia Medical Center and
professor and vice-chair of Surgery at Columbia University.
His research interests include heart replacement surgery, minimally invasive cardiac surgery,
complementary medicine, and health care policy. He has authored over 400 original publications,
book chapters, abstracts, and books in addition to receiving several patents. And all the while, he is
pushing the envelope of what is currently called the “standard of care” and empowering patients to
take charge of their own health and well-being. Put these two pictures of Dr. Oz together and you begin to see the makings of a
movement, one that has the power to change the face of medicine and how it is practiced, even how we think about it.
DR. OZ’S PERSONAL HEALTH AND WELLNESS PROGRAM
Dr. Oz takes the following supplements:
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Omega-3 fatty acids (fish oils)
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Vitamin D3
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Calcium
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Multivitamin daily
For his patients with heart problems, Dr. Oz recommends the following in dosages customized to
the patient:
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Folic acid
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CoQ10
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L-Carnitine
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Niacin (if the patient has high cholesterol)
EXERCISE
Dr. Oz has made a DVD of his personal fitness program, which was designed by his trainer, Joel Harper. He says, “It’s a
straightforward way of getting people to exercise. I’m traveling a lot and don’t have time to go to the gym, but I like to work out
so I put this on my computer and do my workout in my hotel room.
DIET
Dr. Oz eats a Mediterranean-type diet.
As a child, Mehmet Oz thought about what he wanted to be when he grew up and decided he would either be a professional
athlete or a surgeon. He reasoned that there were similarities between the two— both have to deliver the goods every day, and no
one cares how well you performed yesterday. Growing up, it became clear that his abilities in athletics would not lead him to a
stellar career in that field, so he focused on medicine.
After earning an undergraduate degree from Harvard, Dr. Oz enrolled in medical school at the University of Pennsylvania, where
his training was what he called “traditional.” Students were essentially instructed to ignore any real or perceived mind-body
connection and to view and study organs as individual entities. This process, he says, is effective for teaching science-based,
organ-based medicine. And at the time, he found this approach sufficient.
Physicians sometimes claim they find deep insight about human existence bordering on revelation during their early years of
medical school. When Dr. Oz first saw a living, beating heart in a patient’s chest cavity, he was awed by the elegance of how the
organ “twists the blood out of it the way you would wring water from a towel.” He knew then that the heart would become his
specialty. Watching it twisting and turning, he suddenly understood why the heart is so important in so many aspects of life and
culture, from poetry and religion to its association with the soul and love. From that point, he says, “I’ve dedicated my life to
trying to figure out how to help people who are challenged with heart disease.”
But it was near the end of his residency that Dr. Oz met a patient who gave him what he calls an epiphany. He wasn’t prepared
to have the foundation of his education turned upside down by one experience. A woman with a bleeding ulcer was brought into
the emergency room. Though she had lost a lot of blood, a transfusion and a suture would fix her problem. However, the woman
and her family calmly refused the blood transfusion for religious reasons, even though that transfusion could save her life. Dr. Oz
whisked the woman off to the operating room, confident he could eventually get the family’s permission to do the transfusion.
The surgery went well, but the patient showed signs of organ failure due to blood loss and her blood count was at a point where
she should have already died. Still certain he would be doing the transfusion, Dr. Oz was horrified when the family steadfastly
refused. At this point came the epiphany. The patient’s family, was in effect telling Dr. Oz that there was a deeper love, a deeper
belief by which they were living their lives, and that no matter how logical it seemed that she should get the blood, they didn’t
want the blood.
“The woman who was going to die that evening hung out for another day, and then another day, and then another day, and she
finally went home,” Dr. Oz says. “And she never did get that blood. And although I would never recommend, in the future, for
someone not to get the blood, it was to me a very revealing experience, because I began to recognize that as dogmatic as I
thought I could be with my knowledge base, there were certain elements of the healing process I could not capture. And even if I
was right in the science, I could be wrong in the spirit.”
The experience caused Dr. Oz to conclude that there was more to medicine and healing patients than his training had taught
him. He began to investigate other means of healing, and that led him to non-Western medical practices that really weren’t
completely foreign to him. His parents were born in Turkey, and he spent summers and holidays in the country, a place where
non-traditional methods of healing are commonplace. That upbringing probably gave him more of an open mind in regards to
alternative healing methods.
Sometimes these innovative healing therapies were brought to his attention by patients who came to New York Presbyterian
Hospital from all over the world. They had their own healing traditions that had been effective for them in the past and wanted to
continue using them. But they sensed that the modern doctors in this country wanted nothing to do with such things, which
resulted in something Dr. Oz found interesting.
“They would abdicate all responsibility for their care once they walked into our hospital, and so we tried to change that, to give
them the confidence to play an active role in their own recovery process by letting them use their own healing traditions. And
that’s how I actually learned about many of these alternative therapies.”
Dr. Oz became comfortable with seeing the same reality from different perspectives—traditional and non-traditional medicine. He
reached beyond the medical textbooks and conventional thinking to enlarge the paradigm by exploring alternative means of
healing and complementary therapies. Today in his clinical practice, and as director of the Cardiovascular Institute
Complementary Medicine Program at New York Presbyterian Hospital, he boldly brings out-of-the-mainstream techniques such
as meditation, yoga, reflexology, energy healing, and massage into the operating and recovery rooms. He recommends
nutritional supplements, proper diet, stress reduction and exercise, believing there is far more to healing than technology and
pharmaceuticals. His goal is to promote health and wellness in his patients, not just absence of disease.
Some physicians might consider such techniques being used in modern hospitals to be radical at best. But by using them and
showing that they can lead to more positive outcomes, doctors might discover that there is more than one way to practice
medicine, something better than what was taught in medical school.
Says Dr. Oz, “Some people feel I’m on to something big, others disagree. Orthodox medicine
makes people think it’s witchcraft, but I think the truth is in the middle. When you finally figure out
that you’ve got the best technology available, when you’ve finally climbed the last technology
mountain and the patient still doesn’t feel well, you’ve got to look elsewhere. That’s when we start
looking in areas where typically we in the West are much less comfortable—like spirituality and
alternative therapies—things that bridge cultures of healing beyond this country’s borders.”
LE Magazine September 2008
Dr. Mehmet Oz: Global Medicine
By Sue Kovach
Dr. Oz has coined the term global medicine to describe this blending of Western and non-Western methods of healing—two
things he believes do not have to be mutually exclusive. He holds these complementary therapies, some new and some very old,
to the same standards as he does Western techniques, and will only use what he sees is working for the patient.
“If we are to achieve maximum healing, we should use any tool at our disposal—including non-scientific approaches—provided
there is evidence that they do no harm to the patients,” he says.
Maintaining his strong confidence in science, Dr. Oz feels that the standard belief that medicine offers all the solutions has
caused patients to give up the proactive role they should be playing in their own health care. Reclaiming that proactive role has
become his powerful and enabling message to the public, and he is clearly excited about delivering that message to millions
through his books and TV appearances.
This public education aspect of his career began when the news media discovered he was “a good
interview.” Reporters often visit the Columbia University medical school when covering medical
stories, and calls to Dr. Oz became more frequent. Increased exposure as a subject matter expert
led to even more demand for Dr. Oz, and his audience grew tremendously when he appeared on
Oprah Winfrey’s show, appearances that eventually led to regular health and wellness segments.
Dr. Oz seems custom-made for television. He engages the audience with his fascination with the
possibilities of both traditional and complementary medicine. Listening to him, you want to lose
weight, you want to eat better, and live longer. But by educating people in this way, he is helping to
open channels of communication between patients and their doctors so that patients are further
empowered to become more involved in their own health destinies.
Dr. Oz has become a ubiquitous presence on the internet and has also written several enormously
popular books. His breakthrough 1999 book, Healing from the Heart: A Leading Surgeon Combines
Eastern and Western Traditions to Create the Medicine of the Future, recalls his own experiences
as a heart surgeon, his evolution into integrative medicine, and patient success stories. He went on to create the “You” series of
books (co-authored with Dr. Michael Roizen), such as the best-selling You: The Owner’s Manual, You: On a Diet, and You: The
Smart Patient, written to provide people with the information they need to take control of their own health and become
comfortable doing so. His newest book in the series could be the most exciting yet. You: Staying Young, The Owner’s Manual for
Extending Your Warranty brings the field of anti-aging medicine front and center (see sidebar below).
“I think there’s a disconnect between people and their own bodies, an information gap,” he
says. “No one ever said to them, ‘Here’s what’s going on with your body.’ And if they’re not
ready to hear it in the way they want to hear it, that can be scary. America has a lot of health
issues we’re not dealing with, but people need to realize they have a lot of control over this
process. They can learn things on their own and be savvy users of the health care system.
The problem has been that for most people, authentic information can be really hard to get.
But I want to make everyone a smart user of health care and to make sure that everyone’s
getting the best care because both doctor and patient are asking the right questions.”
Dr. Oz encourages people to be prepared for their doctor appointments by developing their personal health profile, a summary of
their health issues and history that includes family history, and to be prepared to discuss critical topics. He advises people to
learn as much as they can from as many sources as they can, and cites Life Extension magazine as “a good resource that’s full
of practical information and articles about supplements that I often find useful.”
“Most patients don’t do a great job of communicating with their doctors because patients often give us docs too little pertinent
information to go on—and remember, just like a detective, we’re looking for the facts,” says Dr. Oz. “At the same time, they may
also give us too many distracting or off-topic details. The first sign of a Smart Patient is that telltale document, the personal
health profile that they produce during their first visit, or even their 50th. This is the sign of a patient who means business, one
who will challenge us to be at our absolute best, and who won’t waste time and money on redundant and unnecessary efforts.”
Between his practice, teaching, writing books, and making media appearances, it is tempting to conclude that Dr. Oz is a man
who probably doesn’t sleep much. The love of his profession and his passion for his message keep him going in all these areas.
He strongly believes that we can turn around the health problems facing the nation today if people will simply take charge of their
own health destiny again.
“I’m passionate about the message. I believe that all health care is personal, and we have to
get Americans to do it for themselves,” he says. “The ultimate solution to the health care
problem in our country will only be found through empowering individuals to take better care of
themselves. It won’t happen otherwise. We can try to delegate healthcare from Washington,
DC, but the only way to get healthy is for individuals to take responsibility to do it on their
own.” With Dr. Oz’s help, we are certainly on the way to doing so.
DR. OZ ON ANTI-AGING: FIVE MAJOR AGERS (AND WHAT YOU CAN DO ABOUT THEM)
In his book, You: Staying Young, The Owner’s Manual for Extending Your Warranty, Dr. Oz
focuses on what he calls the Major Agers, 14 biological processes that control the rate at
which you age. He offers detailed easy-to-understand explanations of these process and
what you can do to combat their negative effects. He also makes diet and supplement
recommendations along with prescriptions for stress reduction and other lifestyle changes.
Most importantly, he notes that it’s never too early or too late to start making positive
changes in your life to combat aging.
“Even if you start making changes late in life, you can still repair the damages that age the
body,” he says. “It’s important to remember that the things we do for longevity are things we
do for ourselves, not things that doctors do for us.”
Here are five Major Agers and what you can do to combat their effects.
1. BAD GENES AND SHORT TELOMERES
Genes are key to determining how you age. While you might be stuck with the genes you’re given, you can help control the
way they’re expressed. Says Dr. Oz, “We’re starting to uncover more and more ways that you can change how your genes
function. For example, just 10 minutes of walking turns on a gene that decreases cancer growth rate, and resveratrol turns on a
gene that slows or stops a dangerous inflammatory process that happens in the body.”
2. DECLINING DEFENSES
When it comes to aging, we’re concerned with acute infections and chronic infections, when
bacteria and other germs trigger a behind-the-scenes inflammatory response that ages your entire
system, says Dr. Oz. Fight declining defenses by getting the nutrients shown to boost your
natural defenses, such as omega-3 fatty acids, resveratrol, catechins (found in green tea),
quercetin, lycopene, biotin, vitamins B6 and B12, ginger, and curcumin.
3. TOXINS
Toxins can chip away at our overall health so we’re much more prone to feeling the effects of
aging, says Dr. Oz. “Some of the toxins that we encounter are potentially very harmful and can
cause cancer, asthma, or allergies, and they can reduce your quality of life in more subtle ways.”
Weakened immune systems from aging that are unable to fight off the Major Ager of toxins create
a perfect storm of cancer-causing factors. To prevent the birth and spread of cancer cells, take these steps:
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Fortify yourself with vitamin D. “Vitamin D decreases the risk of cancer, perhaps because it’s toxic to cancer cells. The
other theory is that D bolsters the ability of the guard-dog p53 gene to spot cancerous cells and kill them.” Most
Americans don’t get enough D—we’re indoors a lot, or wearing sunscreen when we’re outdoors. Dr. Oz’s vitamin D
recommendation: 800 IU a day if you’re younger than 60 and 1,000 IU if you’re over 60. (Editor’s note: Many aging
individuals require far higher doses of vitamin D to achieve optimal status.)
Protect your liver. Certain foods and supplements can help improve liver function and have anti-cancer properties. These
are choline (which can be found in cabbage, cauliflower, and soybeans), as well as N-acetylcysteine, milk thistle,
lecithin (1 tablespoon daily), and rosemary extract .
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B protected. Research shows that folate deficiency is linked to cancer. “Folate supplementation decreases colon
cancer rates by 20 to 50%,” says Dr. Oz. “The amount of folate that seems to reduce colon cancer is 800 micrograms a
day.” The average intake of folate through food: only 275 to 375 micrograms, so you need a supplement to reduce
cancer risk.
Selenium reduces damage that can lead to cancer. Sources include foods like garlic that absorb selenium from the soil.
However, soil in most areas of the country is depleted of selenium. “It seems that taking 200 micrograms of selenium in
organic supplements may help reduce cancer,” says Dr. Oz. “Don’t exceed 600 micrograms a day.”
4. GLYCOSYLATION
Glycosylation occurs when sugar molecules, or glucose, in our blood attach to protein molecules, diminishing their
effectiveness and causing inflammation, says Dr. Oz. This process increases as we age. Glycosylation can lead to
atherosclerosis, cataracts, loss of elasticity in skin, and arthritis. What to do: “Losing weight will immediately shift your body’s
response to insulin and melt away the glycosylation,” says Dr. Oz. Exercise and a healthy diet are also important. Foods and
supplements that can help include ginseng, cinnamon, tea, and chromium, which have been shown to help increase insulin
receptivity and help lower the risk of aging from diabetes.
5. ULTRAVIOLET (UV) RADIATION
We all know that UV radiation from the sun damages skin and can lead to skin cancers. It also destroys your reserves of folic
acid, necessary for your body to replicate DNA properly. But less attention is placed on the damage that UV radiation can do
to your eyes. It can cause oxidative stress, which damages vision by clouding our lens (cataracts) and by damaging the
delicate cells of the retina. It also oxidizes the pigments in the retina, decreasing the antioxidants in the back of the eye,
meaning that these delicate cells are always at risk of being damaged through free radicals. Conditions like macular
degeneration are caused when cells die from oxidative damage. Along with wearing UV-protective sunglasses, nutrition is
important to rebuilding antioxidant stores to protect your eyes.
Dr. Oz recommends:
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Lutein, found in spinach, leafy green vegetables, and corn. You can supplement at 1,000 mcg/day.
The eye cocktail. A National Institutes of Health study found that certain vitamins taken together can help prevent vision
loss for those who have age-related macular degeneration. Researchers found a more than 25% reduction in risk of
vision loss if they took 500 mg of vitamin C, 400 IU of vitamin E, 15 mg of beta-carotene, 80 mg of zinc, and 2 mg of
copper every day in divided doses.
LE Magazine September 2008
You: Staying Young
The Owner’s Manual for Extending Your Warranty
By Michael F. Roizen, MD and Mehmet C. Oz, MD
In best-seller after best-seller, Drs. Mehmet Oz and Michael Roizen use their popular books
as a vehicle to dispense the latest scientific research and medical findings in a format aimed
at educating both patients and doctors with practical information on how to live longer,
healthier lives. Without hesitation, Drs. Oz and Roizen tackle dense but critical topics such as
mitochondrial dysfunction and the role it plays in accelerated aging and translate this into
information that appeals to a wide audience. Below is a brief excerpt of some of the material
contained in their essential guide to successful longevity, You: Staying Young: The Owner’s
Manual for Extending Your Warranty.
STRATEGIC AGING
To add serious years to your life—and life to your years—you have to lower your risk for all diseases. And the only way to do that
is to slow your rate of aging on the cellular level. Curing cancer or any other disease does not necessarily do anything to change
the nature or speed of your bodily aging process. That’s because aging and disease—although they interact with each other—
aren’t the same thing. As we grow older, all of our systems slowly deteriorate, which makes us more vulnerable to disease. By
slowing the aging of our cells while simultaneously preventing disease, we can enjoy not only a higher quality of life but a much
longer one as well.
Because there are huge delays between the cause of the problem and the effects you actually see in your life you have to start
building defenses in your thirties, forties, and fifties against attacks that may not occur until your sixties, seventies, and eighties.
Just because you’ve been dealt a genetic hand that predisposes you to heart disease or
diabetes doesn’t mean that you can’t mitigate the effects of those genes. While you can’t
change your genes, you can change whether they are turned on or off, or how you express
them. Not every aggressive detrimental gene needs to be turned on, and not all of your sleepy
protective genes have to remain dormant.
Despite what you think, aging—in the traditional way that we think of it, with everything slowly
and painfully shutting down—isn’t ‘meant to be.’
The real secret to longevity isn’t whether or not you break; it’s how well you recover and repair
when you do. Our bodies, in fact, weren’t designed not to break down (legs as thick as
redwoods may not break, but they wouldn’t be very nimble). They were designed with a great
efficacy and ability to repair themselves.
Aging is essentially a process in which your cells lose their resilience; they lose their ability to repair damage because the things
like mitochondria and telomeres, aren’t working the way they should. But it’s within your power to boost that resilience and keep
your vehicle going an extra couple hundred thousand miles.
It means that aging is really about the rate of aging—specific-ally, how the outside and inside
factors accelerate or decelerate your aging. Here’s the big secret about aging: your rate of aging
doubles every eight years. So, if we were able to maintain a forty-year-old’s rate of aging for the rest
of our lives, we would live past age one hundred twenty and ‘die of old age.’ While inside out and
outside in both play a role—and both influence each other—your job is to try to manage both forms,
so that you slow the real culprit in growing old: the rate of aging.
The truth about aging is that you—right now—have the ability to live 35% longer than expected
(today’s life expectancy is seventy-five for men and eighty for women) with a greater quality of life
and without frailty. That means it’s reasonable to say that you can get to one hundred or beyond
and enjoy a good quality of life along the way. While relying on the talents, skills, and knowledge of
others may get you out of a medical jam, what you really want is to avoid it in the first place.
Restricting calories, increasing your strength, and getting quality sleep are three of nature’s best
antiaging medicines. Together, these activities—as well as the other actions we recommend—control 70% of how well you age.
The telomeres of people who feel more stressed are almost 50% shorter than people who say they’re less stressed. Since
scientists have a rough idea what the average telomere length is for a specific age, they can estimate how much older the higherstress group is biologically: a whopping nine to seventeen years. Just by thinking they are aging faster, they actually aged faster.
So how do you change the function of your genes? One way is through the rebuilding of chromosomes. Your chromosomes have
small substances on the ends called telomeres. Think of them as being like those little plastic tips of shoelaces. Every time a
cell reproduces, that telomere gets a little shorter, just as the shoelace tip wears off with time.
Nerve cells communicate with one another via neurotransmitters, chemicals that ferry information from neuron to neuron across
the synapses between them. The most common neurotransmitter is called acetylcholine. When levels of this chemical fall,
especially in the hippocampus (the part of the brain that controls our memory), we develop cognitive impairment. Many of the
treatments for Alzheimer’s are aimed at increasing the amount of acetylcholine in the brain. The other chemical that plays a
significant role in memory is called brain-derived neurotrophic factor (BDNF, or just neurotrophins if you prefer), which works like
Miracle-Gro for your brain. During infancy, BDNF helps develop nerves that help us learn, but as we get older, things like
inflammation and stress can decrease its levels. Research shows that you can do things to improve your levels of BDNF, such
as consuming the spice curcumin (a component of turmeric), restricting calories, doing exercise, being in love, and taking some
of a class of antidepressants known as selective serotonin reuptake inhibitors, or SSRIs.
ENHANCE YOUR BRAIN FUNCTION
Feed on brain food. While physics would dictate that your food travels down after you eat it, a certain amount travels up to your
brain (via arteries after it’s been through the digestive process, of course). Among the best nutrients to help keep your cerebral
power lines strong are omega-3 fatty acids—the kinds of fat found in fish like salmon and mahi-mahi. These healthy fats, which
have been shown to slow cognitive decline in people who are at risk, not only help keep your arteries clear but improve the
function of your message sending neurotransmitters. Aim for 13 ounces of fish a week, or, if you prefer supplements, take 2
grams of fish oil a day (molecularly distilled), or DHA from algae (where fish get their omega-3s), or an ounce of walnuts a day.
DHA is the omega-3 that seems best for the brain.
Several substances have been shown to help cognitive function. These are the ones we recommend:
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Carotenoids and flavonoids, which are vitamin-like substances that can act as antioxidants. They tend to give color to
fruits and vegetables.
Lycopene and quercetin. Good sources include tomatoes, pink grapefruit, watermelon, leafy green vegetables, red apples,
onions, cranberries, and blueberries.
Resveratrol, found in red wine. The high doses that have been researched might require too much alcohol (like 180 bottles
a day), so also consider a high-dose purified product as a supplement.
MITOCHONDRIAL HEALTH
Mitochondria (you have hundreds of those per cell) convert nutrients from the food you eat into
energy that your body uses in order to perform all of the functions it needs to. They are the
fundamental drivers of metabolism. They make sure that what you eat fits into how you
perform. Plus, their function (and dysfunction) serves as the backbone for one of the major
theories of aging. The problem is, when mitochondria turn your food into energy, they produce
oxygen free radicals—molecules that cause dangerous inflammation in the mitochondria
themselves as well as in the rest of the cell when they spill over. Think of them as the power
plants of our bodily city. Just like an old factory, aging mitochondria spill more industrial waste
into the environment. The damage this inflammation causes to your cells and to the
mitochondria within your cells is responsible for many age-related problems. This oxidation, for
example, is what causes a “rusting” of your arteries, which is some of what ages your
cardiovascular system. So let’s take a closer look at how mitochondria work.
You have hundreds of mitochondria per cell and dozens of strands of mitochondrial DNA per mitochondrion. That means that
every cell contains thousands of strands of mitochondrial DNA.
If your body can’t produce energy efficiently, it means that mitochondria are not getting the most energy out of the oxygen and
sugar that their furnaces are fed. So even if you have good nutrition in what you eat, lower levels of your body’s energy currency,
called ATP (adenosine triphosphate), are made. We know that mitochondrial damage in the heart happens when your body no
longer consumes oxygen and glucose efficiently. We also see mitochondrial damage in brain-related disease and in diabetes,
where it influences the pancreas’s ability to make insulin. In fact, mitochondrial damage may serve as a contributing factor to
certain types of cancer, because the more oxidative damage that takes place, the more DNA is damaged, and the damaged
DNA, when it’s replicated over and over again, can evolve into a cancer.
To order You: Staying Young: The Owner’s Manual for Extending Your Warranty, by Michael F. Roizen, MD, and Mehmet C. Oz,
MD, please click or call 1-800-544-4440. Retail price $26, member price $18.20.
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