JChrDD  Vol 2  Issue 1  Jan-Apr 2011
Journal of Chronotherapy and Drug Delivery
Editorial
Dear Readers,
We are happy to launch the first issue of Volume 2 of the Journal of Chronotherapy and Drug Delivery.
In this issue, we have five review articles and three research papers. The first review is the second article in the
Special Focus Series on Chronotherapy of Arthritis. There is another review on Chronopharmaceutics. It is a
rather new field of development of formulations and drug delivery systems, that provide the drug at the site of
action according to the chronobiology of the disease. In other terms, it is development of ‘Tailor-made’
medicine as per the requirements of the disease. In this issue, we have another Special Focus section on
‘Colloidal Drug Delivery’. In this section, there are two review articles about liposomes and niosomes,
respectively. There are three research papers.
This time, we have designed a new cover page for the journal, which describes the scope of the journal,
graphically. Readers are requested to kindly provide their comments / suggestions about the cover page, as well
as the quality of papers.
For the use of new readers, I would like to elaborate the scope of the journal again. The Journal of
Chronotherapy and Drug Delivery is being launched to give scope for the publication of papers related to
chronobiology, chronopharmacology, chronotherapeutics, chronopharmaceutics and drug delivery systems.
These are developing fields of modern medicine in western countries, whereas, Indian system of medicine,
Ayurveda, has taken into account the importance of timing in administration of medication. Papers are also
invited which throw light on chronotherapy in Indian, Chinese, and other such traditional herbal medicine
systems.
I request all the pharmaceutical scientists to support the cause of the journal by contributing research as well as
review papers in these areas.
With sincere regards
GT Kulkarni
Editor-in-Chief
http://www.chronotherapyjournal.net
http://www.chronotherapyjournal.com
Editorial / Advisory Board
Editor-in-Chief
Dr GT Kulkarni, Professor and Principal, Laureate Institute of Pharmacy, Kathog, Kangra
Associate Editors
Dr OP Gouda, Maratha Mandal’s College of Pharmacy, Belgaum
Mr Rajendra Awasthi, Laureate Institute of Pharmacy, Kathog, Kangra
EDITORIAL BOARD - NATIONAL
Dr K Gowthamarajan, JSS College of Pharmacy, Ootacamund
Dr Ujwala Shinde, Bombay College of Pharmacy, Mumbai
Dr Subramanian Arunachalam, NISER, Bhubaneswar
Dr HKS Swamy, SJM College of Pharmacy, Chitradurga
Dr Rajasekar Jaladi, Hyderabad
Dr Vijay D Wagh, YB Chavan College of Pharmacy, Aurangabad
Dr Babita Kumar, Dept of Pharmaceutical Sciences, SGIT, Ghaziabad
Dr Bigala Rajkamal, Ganga Pharmacy College, Nizamabad
Dr Jainendra Jain, Depatrment of Pharmacy, RamEesh Institute of Vocational and Technical
Education, Greater Noida
Dr NV Satheesh Madhav, Dehradun Institute of Technology, Dehradun
Dr Rupal Joshi, Zydus Research Center, Ahmedabad
Dr Nagendra Rao, Professor, SCS College of Pharmacy, Harapanahalli
Dr H Shivakumar, Professor, BLDE College of Pharmacy, Bijapur
Dr S Ramachandra Setty, SCS College of Pharmacy, Harapanahalli
Dr TY Pasha, NR Vekaria Institute of Pharmacy, Junagadh
Dr VG Joshi, Maratha Mandal’s College of Pharmacy, Belgaum
Dr Y Anand Kumar, VL College of Pharmacy, Raichur
Dr MS Vijay Kanth, Strides Specialities Pvt Ltd, Bangalore
Dr A Ramakrishna Shabaraya, Srinivasa College of Pharmacy, Mangalore
Dr Srinivas Mutalik, Manipal College of Pharmaceutical Sciences, Manipal
Dr V Rajani Kumar, Axis Clinicals Ltd, Hyderabad
Mr J Thimmasetty, Bapuji Pharmacy College, Davangere
Dr Umesh Kumar Sharma, Sir Madanlal Group of Institutions, Etawah
Mr Nitin Sharma, MIET, Meerut
Dr RV Kulkarni, BLDEA's College of Pharmacy, Bijapur
Dr K Krupanidhi, T John's College of Pharmacy, Bangalore
Dr K Venkatesh, AMRI Hospitals, Dhakuria, Kolkata
Dr D Nagasamy Venkatesh, JSS College of Pharmacy, Ootacamund
EDITORIAL BOARD - INTERNATIONAL
Dr Krishna Kumar Veeravalli, University of Illinois College of Medicine, Peoria, USA
Dr Nalamolu Koteswara Rao, School of Medicine, Taylor’s University College, Malaysia
Dr Sushruta Koppula, College of Biomedical and Health Science, Chungbuk, Korea
Dr Gorajana Adinarayana, International Medical University, Kualalumupr, Malaysia
Dr Kamal Dua, School of Pharmacy and Allied Health Sciences, Kualalumpur, Malaysia
Dr MC Sabu, Department of Food Science and Technology, University Putra Malaysia, Selangor,
Malaysia
Dr Rama Sekhara Reddy, Institute of Biological Chemistry, Washington State University, Washington,
USA
Dr Sunil A Agnihotri, Frontage Laboratories Inc, Exton, PA, USA
Dr Wenshou Wang, Department of Biomedical Engineering, University of Minnesota, USA
Dr Mohammed Altaf Ahmed, Faculty of Pharmacy, IBNSINA Medical University, Jeddah, KSA
ADVISORY BOARD
Dr Sunil Jambhekar, LECOM-Brandenton School of Pharmacy, Bradenton, Florida, USA
Prof (Dr) RB Walker, Faculty of Pharmacy, Rhodes University, Grahamstown, South Africa
Prof VB Desai, Former Drugs Controller of Karnataka, Bangalore
Prof KPR Chaudhary, University College of Pharmaceutical Sciences, Andhra University,
Visakhapatnam
Prof S Satyanarayana, Avanthi Institute of Pharmaceutical Sciences, Vizianagaram
Dr Milind Parle, Dept. of Pharmaceutical Sciences, Guru Jambheshwar University, Hisar
Dr VN Sharma, Dept of Biotechnology, MIET, Meerut
Dr G Vidya Sagar, Veerayatan Institute of Pharmacy, Kutch
Dr PK Manna, Professor, Annamalai Univeristy, Chidambaram
Prof Vijay Bhalla, Spectrum Institute of Pharmaceutical Science and Research, Greater Noida
Dr Shivanand Puthli, Panacea Biotech, Navi Mumbai
Journal of Chronotherapy and Drug Delivery
Vol 2 No 2 May-Aug 2011
Content
S No
Title / Authors
Page
No
REVIEW ARTICLES
1
Chronopharmaceutics: Concept and Technologies
Sundeep Chaurasia, Arvind K, Rahul K, UVS Sara, Giriraj T Kulkarni
57-69
2
Pyridine: Potential for Biological Activities
Sachin Kumar, Pramod Kumar Sharma, Rupesh Dudhe, Nitin Kumar
71-78
3
Recent Advances in Nano Drug Delivery and Nanomedicine
Hitesh K Maradiya, Vasundhara H Pansara, Vidyasagar G
79-87
ORIGINAL RESEARCH PAPERS
1
Factorial Studies on the Effects of Hydroxypropyl -Cyclodextrin and
Poloxamer 407 on the Solubility and Dissolution Rate of BCS Class II
Drugs
Surya Prakasa Rao K, Chowdary KPR
89-93
2
Formulation and in vitro Characterization of Chronopharmaceutical
Drug Delivery System of Metoprolol Tartrate using Hydroxypropyl
Cellulose
Shyam Sunder Agrawal, Subhash Chand Dadarwal, Sarika Madan
95-101