The Johns Hopkins Hospital Medical Nursing Service Standards of Care Manual PROCEDURE FOR WITHDRAWAL OF LIFE SUPPORT IN THE MICU/MCP Policy Number 450 Effective Date 1/22/01 Supercedes 1/09/01 Definition: Withdrawal of life support is defined as withdrawal of ventilatory support with or without extubation and withdrawal or foregoing of additional life sustaining treatments such as: cardiopulmonary resuscitation, vasopressors, blood products, hemodialysis, nutrition, antibiotics; thus allowing natural death to occur from the patient’s underlying disease process. Purpose: To facilitate management and comfort care during the withdrawal process, for patients who are not to be organ donors. This policy will be applicable to patients who are DNR or so designated as part of the implementation of this procedure. It shall apply to patients who are intubated and on mechanical ventilation who are either: a. Experiencing an irreversible terminal illness in whom life support is postponing an unavoidable death (see also JHH Interdisciplinary Clinical Practice Manual Policy #MEL004, "Medically Ineffective or Futile Treatment"). b. Those whose best anticipated outcome from continued care is a state of health inconsistent with the patient’s wishes as documented in the medical record or understood by their family or surrogate decision maker. 1.0 Responsibility: 1.1 The attending physician or fellow is responsible for decisions regarding withdrawal of life support and must be directly involved, prior to implementation of these procedures. Discussions with the patient/surrogate related to withdrawal of life support will be documented in the medical record by the attending or designee (see 2.1.1). 1.2 The MICU/MCP will adhere to the following guidelines when sedation/analgesia are used in conjunction with withdrawal of life support in the MICU. 2.0 Procedure: 2.1 Discuss plan for withdrawal of life support with the multidisciplinary team. 2.1.1 The MICU attending will discuss plans with patient (for patients who are conscious and possess decision-making capacity), family or surrogate/guardian. There may be unusual circumstances when this discussion with the patient or surrogate cannot be held by the MICU attending. For example, important family members may arrive late at night or the patient might precipitously deteriorate when the attending or fellow are out of the hospital. In such cases, it may not be in the patient’s best interest to delay the withdrawal of care until the attending can be present. In these circumstances, the discussion with the patient or their family regarding withdrawal of life support may be held by the MICU resident, but only after consultation with the MICU attending by phone. The attending or designee shall document the conversation, including the element of consent, in the patient’s medical chart. 2.1.1.1 Family conference with family members, nursing, physicians, and other multidisciplinary team members as needed, (i.e., chaplain, social work, respiratory therapy). 2.1.1.2 Consult Palliative Care Team, Ethics Committee and Legal Department as needed (e.g., for conflict resolution, see JHH Interdisciplinary Clinical Practice Manual Policy #MEL004, ‘Medically Ineffective or Futile Treatment’). 2.1.1.3 Direct caregivers (RN or clinical technician) assigned to patient should be comfortable with withdrawal process. If not, attempts should be made to change staff member’s assignment. See Human Resources Policy and Procedure Manual Policy #ELR610, ‘Staff Requests Not To Participate in Patient Care". 2.1.2 Determine if Pastoral Care needs to be present for patient and family support before and/or during withdrawal of life support. 2.1.3 Prepare patient and family for what may occur during withdrawal of life support such as comfort measures of sedation and analgesics that may be given, presence of increased respiratory effort with eventual decline, heart rate variation, decreasing blood pressure, periods of restlessness, and/or skin color changes that may occur. (See Appendix A for more information). 2.1.4 Discuss who needs or wants to be present from family and coordinate timing so that withdrawal will begin when appropriate individuals are present. 2.2 Obtain order for analgesia and sedation utilizing MICU Orderset for Withdrawal of Life Support. Patients who have experienced adverse reactions to either Fentanyl or Ativan, will be ordered pain/sedation agents based on physician judgement. The RN will confirm that attending physician has signed orderset or has discussed orderset with resident or fellow. This is accomplished by checking the progress notes for documentation of conversation with attending. Documentation must be present prior to initiating this policy. Confirm DNR status. Follow orderset to indicate treatments and interventions to be discontinued, if desired. 2.2.1 Initiation and/or continuation of neuromuscular blockade (e.g. pavulon, succinylcholine) is prohibited during the withdrawal of life support. 2.3 Notify Respiratory Therapy that withdrawal of mechanical ventilation is ordered and the possible time frame. 2.4 The physician should discuss the manner and goals of palliative care with the patient and family to determine their desire for analgesia, sedation, or both and then indicate level of sedation desired prior to the withdrawal of life support in the Orderset. Level of Sedation: O = No response 1 = Responds to deep pain only 2 = Drowsy, but hard to arouse; needs tactile stimuli 3 = Drowsy, but will open eyes when name called several times. 4 = Drowsy, but easily aroused, opens eyes when name called. 5 = Awake, oriented x3, or may be delirious, agitated, expressing pain. 2.5 Once patient is sedated to the ordered sedation level and family is ready for withdrawal to occur, notify the respiratory therapist. The respiratory therapist will extubate the patient to room air or per physician’s order (based on an individualized assessment of the particular patient, the physician may choose to gradually decrease ventilatory support, or extubate to oxygen, humidified room air or place on t-piece). The respiratory therapist will document on the ventilator flow sheet the method and time of withdrawal. 2.5.1 If the respiratory therapist requests not to participate in the extubation of the patient, the extubation may be performed by the physician or nursing staff, with respiratory therapist in attendance (see Human Resources Policy and Procedure Manual Policy #ELR610, "Staff Requests Not To Participate in Patient Care". 2.6 Monitor the patient continuously for signs of discomfort and distress and administer additional sedative/pain medication per orderset as needed for comfort, unless the physician provides alternative orders. Do not withhold medication for comfort if the patient becomes hypotensive, bradycardic, or there is a decrease in the level of consciousness. Signs that indicate discomfort and/or distress are: 2.6.1 Moderate to severe use of accessory muscles. 2.6.2 Respiratory rate exceeding 35/minute. 2.6.3 Gasping, noisy and/or increased respiratory effort, coughing or choking. 2.6.4 Increased agitation, unnecessary movement of head, legs, torso, or facial grimacing. 2.6.5 Increased heart rate or mean arterial pressure more than 20% above the level prior to withdrawal of life support, before or after sedation. 2.7 The RN will document the time the withdrawal process was initiated and the sedation level prior to withdrawal in the vital sign section of the nursing flowsheet. Document the rationale (as listed in 2.6) for administering additional sedation or analgesics in the nurse’s notes section. This should occur with all doses or drip changes given for the comfort of the patient after withdrawal of life support. 2.8 Cardiac monitoring display in the patient’s room may be discontinued during the withdrawal process based on the discretion of the health care team or as requested by family. 2.9 Once patient has died, allow the family time with the patient. Remove all equipment and tubes, unless otherwise indicated (i.e., autopsy). 2.10 Allow time for staff member caring for patient and other members of the health care team to express their feelings [after patient’s death] as a debriefing event. 2.11 If the surrogate decision-maker reconsiders withdrawal of life support, hold current settings of sedatives/analgesics (do not increase titration), notify physician immediately, and prepare to reinitiate life support and readdress code status. See Also: Do Not Resuscitate Policy, Interdisciplinary Clinical Practice Manual, PAT005. Medically Ineffective or Futile Treatment, Interdisciplinary Clinical Practice Manual, MEL 004. Staff Requests Not to Participate in Patient Care, Human Resource Policy and Procedure Manual, ELR 610. Education: All MICU attendings and fellows will be informed of and trained in this policy by the MICU Medical Director. Housestaff will be instructed in the policy as needed (i.e., when the policy is to be invoked on a specific patient). Nurse Manager or designee will be responsible to train nursing staff. Reviewed by: Dr. Roy Brower, Dr. Henry Fessler (MICU Attending Physicians) Risk Management Medical Staff Risk Management Committee Administrative Committee of the Medical Board Medical Care Evaluation Committee Critical Care Committee Ethics Committee Medical Board References: Campbell, Margaret, C., 1998, Forgoing Life-Sustaining Therapy, How to Care for the Patient Who is Near Death. Daly, B., Thomas, D., and Dyer, M.A., Procedures Used in Withdrawal of Mechanical Ventilation. American Journal of Critical Care, 1996, 5(5), 331-338. THE JOHNS HOPKINS MEDICAL NURSING SERVICE STANDARDS OF CARE MANUAL ORIGINAL: 2/00 1/22/01 DRAFT 12 Revised: 3/00, 5/00, 7/6/00, 8/28/00, 10/3/00, 10/11/00, 11/30/00, 1/9/01 ,