Kidney - Ukiah Adult School

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A&P of the Urinary System

Week 44

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1

Objectives

•Identify the organs of the urinary system, from a

•Identify the parts of the nephron (the functional unit

•List the characteristics of a normal urine specimen.

•Give a list of abnormal findings, briefly explain the

•State normal and minimal urine outputs.

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2 drawing, and explain their functions.

of the kidney) and explain in brief their functions.

disease or disorder causing these.

Objectives

• Define key words.

• Describe various procedures used in diagnosis of disease and disorders of the urinary system, giving the nursing responsibilities for each.

• Differentiate between normal and abnormal laboratory findings.

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3

• Two kidneys

• Retroperitoneal

• Adipose cushion

Kidneys

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Functions of the kidney

• Maintenance of pH

• Regulation of water and electrolyte elimination

• Elimination of waste products and toxic substances

• Stimulation of red blood cell production

(erythropoieten)

• Contributes to control of blood pressure

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Internal Structure

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Nephrons

• Functioning part of the kidney

• 2 types: cortical (superficial) & juxtamedullary

• In both types the distal tubule empties into the collecting tubules

• Consists of

• glomerulus, water and solutes are filtered from the blood

• Tubules, reabsorb essential minerals from the filtrate and permit waste substances to be eliminated

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The Nephron

• Functional unit of the kidney

• 1 million nephrons per kidney

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Urine is produced by

• Glomerular filtration

• Tubular reabsorption

• Tubular secretion

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Glomerular filtration

Filtration = The forcing of fluids and dissolved substances through a membrane by pressure

• Occurs in the glomerolus

• Composition of filtrate similar to plasma containing glucose, amino acids, salts urea and uric acid

• Blood and proteins only when damaged

• Approximately 600mls blood pass through glomerolus/minute – only 120mls becomes filtrate

• GFR= amount of filtrate formed/minute (about 100-

125ml)

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Tubular re-absorption

• 99% of filtrate is re-absorbed allowing body to retain essential nutrients and fluid

• All glucose should be reabsorbed

• Majority of sodium and potassium are actively reabsorbed from proximal convoluted tubule

• Na reabsorption depends on blood pressure

• ADH makes distal convoluted tubule more permeable therefore more water reabsorbed

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Mechanisms of Reabsorption

• Active transport

• Passive transport

• Osmosis

• Pinocytosis

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Tubular secretion

• From blood into filtrate

• Includes k, H, creatinine and certain drugs

• If Na is reabsorbed K is secreted

(controlled by aldosterone)

• HCO

3 is increase or decreased to regulate pH

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Hormones

• Aldosterone

• Atrial natriuretic peptide (ANP)

• Antidiuretic hormone (ADH)

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Pre-requisite for normal urine production

• Adequate Blood Supply Pre Renal

• Normal Kidney Renal

• No obstruction to urine flow Post Renal

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Definitions

• Normal urine output > 1ml/Kg/Hr

1– 2L/day

• Oliguria 400 ml/ Day

• Anuria

• Absolute Anuria

<100 ml/day nil

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Characteristics of Urine

• Amount: 1- 2 liters/24 hours

• Color: straw or amber, clear

• Specific gravity: 1.010- 1.025

• pH: 4.6- 8.0

• 95% water

• Nitrogenous wastes: Urea, creatinine, uric acid,

• Urobilinogen

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Abnormal Constituents

• Glucose

• Protein

• Blood

• Bacteria

• Ketones

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Do not permit urine volume to fall below

0.5mls/Kg/min for more than 2 hours without investigation or treatment

If you do Acute tubular necrosis may develop and this is very BAD

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Other Functions

• Renin secretion– maintain Cardiac output and

BP

• Secretion of erthropoeitin

• Activation of vitamin D

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• Kidney

• Ureter

• Bladder

• Urethra

Elimination

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Urination Reflex

• Urination= micturation- voiding

• Reflex that can be voluntarily controlled

• Bladder volume: approx

800mL max

• Stimulation occurs with

200- 400mL

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Aging and the Urinary System

• Number of nephrons decreases

• Lose ability to concentrate urine

• Bladder decreases in size

• Decreased detrusor muscle tone

• Creatinine clearance decreases

• Greater incidence of nocturia

• Incontinence is not normal at any age

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Assessment

• Skin color, presence of crystals, turgor

• Respiratory rate and rhythm

• Edema

• Tenderness

• Urine characteristic

• Palpate bladder

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Labwork

• Urinalysis

• Urine culture and sensitivity

• Creatinine clearance

• BUN

• Serum creatinine

• Serum electrolytes

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Radiographic Studies

• KUB

• IVP

• Arteriogram

• Cystogram

• Renal Scan

• CT

• MRI

• Ultrasonography

• Renal Biopsy

• Cystoscopy

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Cystogram

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Common Therapeutic Procedures

• Urethral Catheterization

• Ureteral Catheterization

• Nephrostomy tube

• Urinary stent

• Nephrectomy

• Lithotripsy

• Cystectomy

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