Unit Plan: Genetic Processes HS ­ Science Group Members: Artimis Soltanidji, Benjamin Liu, Ahamed Basheer Instructors: Janine Extavour, Marty Zatzman 1 Context for developing skills and conceptual knowledge necessary for making connections between scientific, technological, social, and environmental issues. In this unit, students will learn to apply their knowledge to a very tangible and topical issue within society: genetic diversity. They will learn to apply their knowledge of inheritance, genetic processes, diseases, and statistical analysis of genetics to allow them to understand the diversity and differences in all organisms. Furthermore, they will learn to think critically about the societal implications of various genetic technologies, such as cloning, recombinant DNA and gene therapy, and ultimately become informed citizens about these issues. Lesson Sequence Day 1 2 3 Learning Goals Overview Students will be able to formulate suitable questions for their culminating task This lesson will introduce the culminating task to the students, and teach students how to create appropriate questions for the unit through Bloom's taxonomy. Students will look at the implications of various reproductive technologies This lesson will introduce societal implications of genetic manipulation, and allow the students to debate and discuss viewpoints on their given topic. Students will activate prior knowledge about cells, chromosomes, and mitosis. Curriculum Expectations Visual: Video of Bloom's taxonomy A1.11 Auditory: Video of Bloom's taxonomy and discussion. Visual: reading the background information of their topic 4 This lesson will look in-depth at chromosomes and their structure, including genes. They will learn the di!erence between gametes and D3.1 definition of haploid, and somatic cells and zygotes and definition of diploid. The basic steps of meiosis, in relation to mitosis, will be discussed. D3.2 Appendices Socratic lecture Critical thinking: Creation of H.O.T. questions for culmninating activity. Exit-card: Creation of suitable questions based on video Appendix I Culminating handout Visual: Diagrams of cells, chromosomes, and mitosis. Socratic lecture Appendix III Mitosis cut-out worksheet Auditory: Listening to teacher Collaborative learning: students will work together to complete the cut-out of the phases of mitosis Tactile: cut-out of mitosis Graphic organizer: mitosis-cut out exercise Students will hand in their cut-out worksheet of mitosis for evaluation. Appendix IV Mitosis vs meiosis handout Visual: Diagrams of chromosomal structure, and steps of meiosis Socratic lecture Auditory: Listening to teacher Graphic organizer: Mitosis vs. meiosis handout. Assessment/Evaluation Appendix II Background information sheet of topic, and debate notes Auditory: listening to the arguments of the other side This lesson will review cell structure, basic chromosomal D 3.2 structure, and the process of mitosis Teaching strategies Student-directed learning: Working through ethical arguments for debate. Class discussion of societal implications, and teacher feedback of misconceptions or questions about issue.. Collaborative-learning: Working in groups for debate. D3.5 D2.1: A1.11 Students will be able to e!ectively use language related to basic genetics, and understand the process of meiosis. Learning strategies 2 White-board quiz: ask them Appendix IV to draw the phases of meiosis, Mitosis vs meiosis and to distinguish between handout haploid and diploid cells Collaborative learning: Working in pairs to fill-in and complete the worksheet based on the video. D2.1: A1.11 5 Students will be able to explain how genetic diversity is created during meiosis. This lesson will explain the creation D2.2: A1.6, A1.8, of greater diversity during meiosis A1.12 through homologous recombination and crossing over, as well as random assortment. The model of meiosis revised from the previous day. D.3.1 Visual and auditory: Online video of meiosis. Graphic organizer: Meiosis and crossing over handout. D3.2 6 This lesson will look at how genetic D2.1: A.11 Students will be able to disorders occur with nonexplain how genetic disorders disjunction (e.g. such as Down’s involving full-chromosomes Syndrome [polysomy], or Turner occur. syndrome [monosomy].) D3.4 Appendix V Students hand in their sheets Online video of to be evaluated for their meiosis and Student-directed learning: understanding of the phases crossing over Using online video to fill- of meiosis, and crossing over. handout in handout. Visual: Watching online flash video of nondisjunction. Student-directed learning: using online flash video to Teacher-led questioning and assessment using the "tra!c fill in handout. light" diagnostic assessment tool Graphic organizer: meiosis I and meiosis II handout Appendix VI Non-disjunction in meiosis I and meiosis II handout A1.3 7 Students will choose a topic for research for their casestudy and begin research. A1.7 Introduce case-study assignment for genetic diseases, and have students A1.9 choose their topic. They will have the remainder of the period to work A1.11 down in computer lab/library. 3-2-1 assessment of their research. (i.e. 3 things they have learned from their research, 2 questions they have, 1 thing they are looking forward to learn) Appendix VII Case-study handout Observation of activity, and managing di!culties with concept Appendix VIII Baby-making lab D1.2 D3.4 8 Students will be able to understand the basics of Mendelian genetics and inheritance, and the diversity in genes. Introduce Mendelian genetics, dominant and recessive alleles, genotype and phenotype, homozygosity and heterozygosity for a trait. Also, production of gametes from parental alleles and their pairing. Look at various physical traits controlled by these alleles, Visual: Creation of a baby from the baby-making lab. D2.1: A1.12 Socratic lecture Auditory: Teacher instruction D3.3 9 Students will understand their topic from their case-study with greater depth and obtain feedback on their progress. Students will continue their research down in computer lab/library for genetic diseases (same as day ) assignment. During this time, each student will be interviewed (assessed) in their progress. 10 Students will be able to create Punnett Squares to predict the outcomes of genetic crossings. Introduce 1 x 1 to 2 x 2 Punnett Squares for a single trait, and ratios/percentages of genotypes and D2.3: A1.6, A1.8, phenotypes. Introduce 2 x 2 to 4 x 4 A1.12 Punnett Sqaures for dual traits, and determine the ratios/percentages. Tactile and Kinesthetic: Manipulation of probability of alleles through flipping a coin. Teacher assessment and feedback Visual: Punnett squares and visual representation of phenotypes Problem sets on board or overhead Socratic lecture Auditory: Listening to teacher Collaborative learning: baby-making lab/game 3 Homework and homework check assessment Appendix IX Mendelian Genetics Worksheet Students will be able to explain how other nonMendelian forms of inheritance occur. Introduce non-Mendelian inheritance with respect to incomplete dominance, codominance, multifactorial traits, and sex-linkage. 12 Students will refine their understanding of genetic crossing of Mendelian and non-Mendelian inheritance through the use of Punnett Squares. They will also obtain feedback on their progress on their culminating task. D2.4: A1.6, A1.8, Students will perform paired A1.12 activity (T/P/S) of various monohybrid and dihybrid crosses. While they are working, the teacher will interview (assess) culminating student pairs on their progress with A1.12 their culminating activity. 13 Students will consolidate their research and will understand their topic from their case study thoroughly. Students will be in-class to put together their case-study assignment, and prepare for their presentations of their research. (same as day 7) 14, 15 Students will understand the causes of various genetic disorders, symptoms, and the techniques of detection and treatment. Students will present their casestudy research D1.2 11 D2.3: A1.6, A1.8, A.12 Visual: Punnett squares and visual representation of phenotypes 17, 18 Students will be reintroduced Students will present their to all the topics taught in the culminating tasks to the class. unit. Visual: Punnett squares problems Homework and homework check assessment Student-directed learning: T/P/S done on their own first. Collaborative learning: Auditory: listening to one Student pairs will share another share their answer to the T/P/S problems. Auditory: listening to other students' presentation Auditory - Listening to the other students' presentations. Visual, Auditory, Tactile, Kinesthetic: All will be used while playing each other's games created for their culminating. Test day 4 Appendix VII Case-study handout Peer-evaluation of presentation. Student-directed learning: students will review the basics of the unit by listening to each other's Teacher-evaluation of presentations. presentation. Appendix I Culminating handout Student-directed learning: Students will review the unit by answering questions of the culminating games. Appendix I Culminating handout Collaborative learning: Students will work together while playing each other's culminating games. 3-2-1 Assessment (3 things they will remember from genetics, 2 questions they still have, and 1 thing they would still like to know) Appendix X Teacher rubric for presentation and task Test evaluation Appendix X T/P/S problem set handed in T/P/S of genetics to be evaluated handout Student-directed learning: Teacher evaluation of listening to the research presentation. presented by their peers. Teacher-directed learning: Questions will be answered, and additional feedback will be given to students. 19 Appendix IX Mendelian Genetics Worksheet Visual diagnostic assessment of student work A1.11 Students will have the opportunity to play with each other's Students will review the entire culminating projects, which will course material in preparation help them review for the test. They D2.1-D3.5 for the test. will also have the opportunity to ask the teacher any problems they may have with the material. Socratic lecture Auditory: Listening to teacher Visual - Watching the presentations and the culminating creations of the other students. 15, 16 Problem sets on board or overhead Accomodations for ELLS: • Foldables for vocabulary and diagrams • Word‐walls • Extra time for evaluations • Allow • Regular checkpoints throughout unit • Graphic organizers around room Accomodations for special education learners: • Environmental accommodations (i.e. closer to front) • Regular checkpoints throughout unit • More scaffolded assessment/evaluation structure • Chunking of lesson topics • Peer scribes • Concrete visual aids set around room Annotated references: Bowers, R., et al. Biology 11. Pearson Education – Addison Wesley. 2002. Toronto. This textbook is a standard textbook that has been used for many highschools to teacher Grade 11 University Biology. It has a very structured and logical layout of topics, as well as enough descriptions and pictures to create a well‐balanced, and informative text‐book. Bowers, R., et al. Biology 11: Teacher’s Resource Guide. Pearson Education. 2002. Toronto. This is the companion teachers resource guide to the Pearson – Addison Wesley textbook. It is full of excellent teacher suggestions for strategies, accomodations, misconceptions, as well as nicely laid‐out BLMs. 5 Evaluation Plan 6