(Last updated: 2016-05-13)
Goo Taeg Oh, D.V.M., Ph.D
ADDRESS
Science Building C #305, Ewha Womans University, 52 Ewhayeodae-gil, Seodaemun-gu,
Seoul 03760, Korea
URL : http://home.ewha.ac.kr/~genomics
Education and Training
1990-1993 Ph.D.
in Veterinary Medicine
Seoul National University, Seoul, Korea
1987-1989 M.S.
in Veterinary Medicine
Seoul National University, Seoul, Korea
1981-1987 B.S.
in Veterinary Medicine
Seoul National University, Seoul, Korea
Professional Experiences
2014-present
2004-2009
Distinguished Professor
Department of Life Sciences, Ewha Womans University, Seoul,
Korea
2009-2013 Professor
Department of Life Sciences, Ewha Womans University, Seoul,
Korea
Associate Professor
2012-present
Department of Life Sciences, Ewha Womans University, Seoul,
Korea
Director
National Creative Initiatives Center for Immune and Vascular Cell
Network, National Research Foundation of Korea
2010-2014
2010-2011 Visiting Professor
Harvard Medical School Division of Vascular Medicine, USA
2007-2012
Review Board
National Research Foundation of Korea
Head
National Research Laboratory Program (NRL),
National Research Foundation of Korea
1995-1997 Research Associate Fellow
1

1988-2004
University of North Carolina (Chapell Hill, NC) Department of
Pathology Head, USA
Senior Research Scientist, Principal Research Scientist
Korea Research Institute of Bioscience & Biotechnology(KRIBB)
Publications(2010-2016)
1. Tae Jin Yun, Jun Seong Lee, Kawthar Machmach, Dahee Shim, Hyung Seok Jang, In-
Hyuk Jung, Kyeongdae Kim, Junhee Choi, Young Jin Wi, Won Kee Yoon, Mohammad
Alam Miah, Mariana G. Bego, Tram N. Q. Pham, Seung-Pyo Lee, Tibor Keler, Jean V.
Guimod, Elie Haddad, Eric A. Cohen, Martin G. Sirois, Ismail El-Hamamsy, Marco
Colonna, Goo Taeg Oh * , Jae-Hoon Choi * , and Cheolho Cheong * . Aortic Plasmacytoid
Dendritic Cells Elicit a Protective Immune Response Against Atherosclerosis. Cell
Metabolism.
2016 In Press *(Co-corresponding Author)
2. Jong Kyu Woo, Yeong-Su Jang, Ju-Hee Kang, Jong-Ik Hwang, Je Kyung Seong, Sang-
Jin Lee, Sejin Jeon, Goo Taeg Oh, Ho-Young Lee, Seung Hyun Oh. Ninjurin1 inhibits colitis-mediated colon cancer development and growth by suppression of macrophage infiltration through repression of FAK signaling. Oncotarget.
2016 Apr 26 Epub
3. Hye Suk Kang, Ho-Chan Cho, Jae-Ho Lee, Goo Taeg Oh, Seung-Hoi Koo, Byung-Hyun
Park, In-Kyu Lee, Hueng-Sik Choi, Dae-Kyu Song & Seung-Soon Im. Metformin stimulat es IGFBP-2 gene expression through PPARalpha in diabetic states. Sci Rep. 2016 Mar
24;6:23665
4. Se-Jin Jeong, Jong-Gil Park, Sinai Kim, Hyae Yon Kweon, Seungwoon Seo, Dae-Seung
Na, Dongho Lee, Cheol Yi Hong, Chun-Soo Na, Mi-Sook Dong, Goo Taeg Oh * . Extract of Rhus verniciflua stokes protects the diet-induced hyperlipidemia in mice. Archives of
Pharmacal Research.
2015 Nov;38(11):2049-2058
5. Hye Suk Kang, Mi-Young Kim, Seung-jae Kim, Jae-ho Lee, Yong-deuk Kim, Young-kyo
Seo, Jae-hoon Bae, Goo-taeg Oh, Dae-kyu Song, Yong-Ho Ahn and Seung-Soon Im.
Regulation of IGFBP-2 expression during fasting. Biochemical Journal . 2015 May
1;467(3):453-460
6. Mi-Ran Lee, Dahee Shim, Jihye Yoon, Hyung Seok Jang, Se-Woong Oh, Suk Hyo Suh,
Jae-Hoon Choi * , Goo Taeg Oh * . Retnla overexpression attenuates allergic inflammation of the airway. PLoS One.
2014 Nov 21;9(11):e112666 *(Co-corresponding Author)
7. Haejin Yoon, Hye-Lim Kim, Yang-Sook Chun, Dong Hoon Shin, Kyoung-Hwa Lee, Chan
Soo Shin, Dong Yeon Lee, Hong-Hee Kim, Zang Hee Lee, Hyun-Mo Ryoo, Mi-Ni Lee,
Goo Taeg Oh * , Jong-Wan Park * .NAA10 controls osteoblast differentiation and bone formation as a feedback regulator of Runx2. Nature Communications. 2014 Nov
7;5:5176 *(Co-corresponding Author)
8. S-H Shin, H Yoon, Y-S Chun, H-W Shin, M-N Lee, GT Oh, J-W Park. Arrest defective 1 regulates the oxidative stress response in human cells and mice by acetylating methionine sulfoxide reductase A. Cell Death Dis.
2014 Oct 23;5:e1490
9. In-Hyuk Jung, Jae-Hoon Choi, Jing Jin, Se-Jin Jeong, Sejin Jeon, Chaeji Lim, Mi-Ran
Lee, Ji-Young Yoo, Seong-Keun Sonn, Young Ho Kim, Beom Kyu Choi, Byoung S.
Kwon, Ju-Young Seoh, Cheol Whan Lee, Dae-Yong Kim, Goo Taeg Oh * . CD137inducing factors from T cells and macrophages accelerate the destabilization of atherosclerotic plaques in hyperlipidemic mice. FASEB J.
2014 Nov;28(11):4779-4791
10. Mi-Ran Lee, Chae-ji Lim, You-Han Lee, Jong-Gil Park, Seong Keun Sonn, Mi-Ni Lee, In-
Hyuk Jung, Se-Jin Jeong, Sejin Jeon, Myoungsook Lee, Ki Sook Oh, Young Yang, Jae
2

Bum Kim, Hueng-Sik Choi, Woojin Jeong, Tae-Sook Jeong, Won Kee Yoon, Hyoung
Chin Kim, Jae-Hoon Choi, Goo Taeg Oh * . The adipokine Retnla modulates cholesterol homeostasis in hyperlipidemic mice. Nature Communications.
2014 Jul 15;5:4410
11. Guo Nan Yin, Min Ji Choi, Woo Jean Kim, Mi-Hye Kwon, Kang-Moon Song, Jin-Mi Park,
Nando Dulal Das, Ki-Dong Kwon, Dulguun Batbold, Goo Taeg Oh, Gou Young Koh,
Kyu-Won Kim, Ji-Kan Ryu, Jun-Kyu Suh. Inhibition of Ninjurin 1 restores erectile function through dual angiogenic and neurotrophic effects in the diabetic mouse. Proc Natl Acad
Sci U S A.
2014 Jul 1;111(26):E2731-2740
12. Jin-Hwa Choi, Minh-Phuong Nguyen, Dongjin Lee, Goo Taeg Oh, You-Mie Lee.
Hypoxia-Induced Endothelial Progenitor Cell Function Is Blunted in Angiotensinogen
Knockout Mice. Mol Cells.
2014 Jun 30;37(6):487-496
13. Bum Ju Ahn, Hoang Le, Min Wook Shin, Sung -Jin Bae, Eun Ji Lee, Sung Yi Lee, Ju
Hee Yang, Hee-Jun Wee, Jong-Ho Cha, Ji Hae Seo, Hye Shin Lee, Hyo-Jong Lee, Ken
Arai, Eng H. Lo, Sejin Jeon, Goo Tae Oh, Woo Jean Kim, Ji-Kan Ryu, Jun-Kyu Suh, Kyu
-Won Kim. Ninjurin1 enhances the basal motility and transendothelial migration of immune cells by inducing protrusive membrane dynamics. J Biol Chem.
2014 Jun 10
Epub
14. Hye Young Kim, Sung Bae Lee, Hyen Sam Kang, Goo Taeg Oh, Tae Soo Kim. Two distinct domains of Flo8 activator mediates its role in transcriptional activation and the physical interaction with Mss11. Biochem Biophys Res Commun.
2014 Jun
27;449(2):202-207
15. Un Yung Choi, Ji Yeon Hur, Myeong Sup Lee, Quanri Zhang, Won Young Choi, Lark
Kyun Kim, Wook-Bin Lee, Goo Taeg Oh, Young-Joon Kim. Tripartite Motif-Containing
Protein 30 Modulates TCR-Activated Proliferation and Effector Functions in CD4+ T
Cells. PLoS One 2014 Apr 22;9(4):e95805
16. Seung-Hwan Lee, Dong-Young Kim, Yoon-Young Kang, Hyesoon Kim, Jungin Jang, Mi-
Ni Lee, Goo Taeg Oh, Sang-Wook Kang, Eun Young Choi. Developmental endothelial locus-1 inhibits MIF production through suppression of NF-
κB in macrophages.
Int J Mol
Med 2014 Apr;33(4):919-924
17. Bum Ju Ahn, Hoang Le, Min Wook Shin, Sung-Jin Bae, Eun Ji Lee, Hee-Jun Wee,
Jong-Ho Cha, Hyo-Jong Lee, Hye Shin Lee, Jeong Hun Kim, Chang-Yeon Kim, Ji Hae
Seo, Eng H. Lo, Sejin Jeon, Mi-Ni Lee, Goo Taeg Oh, Guo Nan Yin, Ji-Kan Ryu, Jun-
Kyu Suh, Kyu-Won Kim. Ninjurin1 deficiency attenuates susceptibility of experimental autoimmune encephalomyelitis in mice. J Biol Chem 2014 Feb 7;289(6):3328-3338
18. Hyesoon Kim, Seung-Hwan Lee, Mi-Ni Lee, Goo Taeg Oh, Kyung-Chul Choi, Eun
Young Choi. p53 regulates the transcription of the anti-inflammatory molecule developmental endothelial locus-1 (Del-1). Oncotarget.
2013 Nov;4(11):1976-1985
19. Ji Yong Jang, Ji Hyun Min, Yun Hee Chae, Jin Young Baek, Su Bin Wang, Su Jin Park,
Goo Taeg Oh, Sang-Hak Lee, Ye-Shih Ho, Tong-Shin Chang. Reactive oxygen species play a critical role in collagen-induced platelet activation via SHP-2 oxidation. Antioxid
Redox Signal.
2014 Jun 1;20(16):2528-2540
20. Se-Woong Oh, Bora Kim, Sejin Jeon, Du-Min Go, Min-Kyoung Kim, Kyoung Baek, Goo
Taeg Oh, Dae-
Yong Kim. Identification and characterization of CW108F, a Novel β
carboline compound that promotes cardiomyogenesis of stem cells. Life Sci. 2013 Sep
17;93(9-11):409-415
21. Woosung Shin, Jeongyeon Yoon, Goo Taeg Oh, Sungwoo Ryoo. Korean red ginseng inhibits arginase and contributes to endotheliumdependent vasorelaxation through endothelial nitric oxide synthase coupling. J Ginseng Res.
2013 March; 37(1): 64–73
22. Chul-Su Yang, Jae-Min Yuk, Jwa-Jin Kim, Jung Hwan Hwang, Chul-Ho Lee, Jin-Man
Kim, Goo Taeg Oh, Hueng-Sik Choi, Eun-Kyeong Jo. Small Heterodimer Partner-
3

Targeting Therapy Inhibits Systemic Inflammatory Responses through Mitochondrial
Uncoupling Protein 2. PLoS One.
2013 May 21;8(5):e63435
23. Myeong Sup Lee, Byungil Kim, Goo Taeg Oh, Young-Joon Kim. OASL1 inhibits translation of the type I interferon-regulating transcription factor IRF7. Nat Immunol.
2013 Apr;14(4):346-355
24. So Jung An, Un Ju Jung, Myung-Sook Choi, Chan Kyu Chae, Goo Taek Oh, Yong Bok
Park. Functions of monocyte chemotactic protein-3 in transgenic mice fed a high-fat, high-cholesterol diet. J Microbiol Biotechnol.
2013 Mar;23(3):405-413
25. Je Yeong Ko, Kyung Hyun Yoo, Seon Ah Song, Do Yeon Kim, Hyun Kyung Kong, Curie
Ahn, Han Woong Lee, Duk-Hee Kang, Goo Taeg Oh, Jong Hoon Park. Inactivation of
Max Interacting Protein 1 Induces Renal Cilia Disassembly through Reduction in Levels of Intraflagellar Transport 20 in Polycystic Kidney. J Biol Chem.
2013 Mar
1;288(9):6488-6497
26. Jong-Gil Park, Su Yeon Ryu, In-Hyuk Jung, You-Han Lee, Kyung Jae Kang, Mi-Ran Lee,
Mi-Ni Lee, Seong Keun Sonn, Jeong Hwa Lee, Hang Lee, Goo Taeg Oh, Kyungduk
Moon, Hyunbo Shim. Evaluation of VCAM-1 antibodies as therapeutic agent for atherosclerosis in apolipoprotein E-deficient mice. Atherosclerosis. 2013
Feb;226(2):356-363.
27. Se-Woong Oh, Jung Bok Lee, Bora Kim, Sejin Jeon, Min-Kyoung Kim, Ki-Hoan Nam,
Jong-Ryul Ha, Mickie Bhatia, Goo Taeg Oh, Dae-Yong Kim. Peptidomimetic smallmolecule compounds promoting cardiogenesis of stem cells. Arch Pharm Res.
2012
Nov;35(11):1979-1988
28. Yujeong Cho, Jeehye Maeng, Jungmin Ryu, Hyekyoung Shin, Miyoung Kim, Goo Taeg
Oh, Moo-Yeol Lee, Kyunglim Lee. Hypertension resulting from overexpression of translationally controlled tumor protein increases the severity of atherosclerosis in apolipoprotein E knock-out mice. Transgenic Res.
2012 Dec;21(6):1245-1254
29. Qian Zhou, Yu Mei, Takuhito Shoji, Xinbing Han, Karol Kaminski, Goo Taeg Oh, Pat P.
Ongusaha, Kunzhong Zhang, Hannah Schmitt, Martin Moser, Christoph Bode, James K.
Liao. Rho-associated coiled-coil-containing kinase 2 deficiency in bone marrow-derived cells leads to increased cholesterol efflux and decreased atherosclerosis. Circulation.
2012 Oct 30;126(18):2236-2247, 2012
30. Young-June Jin, Jeong-Hyung Lee, Young-Myeong Kim, Goo Taeg Oh, Hansoo Lee.
Macrophage inhibitory cytokine-1 stimulates proliferation of human umbilical vein endothelial cells by up-regulating cyclins D1 and E through the PI3K/Akt-, ERK-, and
JNK-dependent AP-1 and E2F activation signaling pathways. Cell Signal.
2012
Aug;24(8):1485-1495
31. Sangmi Ock, Jihyun Ahn, Seok Hong Lee, Hongryeol Park, Jang Won Son, Jae Gyun
Oh, Dong Kwon Yang, Wang Soo Lee, Ho-Shik Kim, Jaerang Rho, Goo Taeg Oh, Evan
Dale Abel, Woo Jin Park, Jeong-Ki Min, Jaetaek Kim. Receptor activator of nuclear factor-
κB ligand is a novel inducer of myocardial inflammation.
Cardiovasc Res.
2012
Apr 1;94(1):105-114
32. Jeongho Kwon, Eunhye Han, Chi-Bao Bui, Woochul Shin, Junho Lee, Sejeong Lee,
Young-Bong Choi, Ann-Hwee Lee, Kyong-Hoon Lee, Chankyu Park, Martin S Obin,
Sung Kyu Park, Yun Jeong Seo, Goo Taeg Oh, Han-Woong Lee, Jaekyoon Shin.
Assurance of mitochondrial integrity and mammalian longevity by the p62-Keap1-Nrf2-
Nqo1 cascade. EMBO Rep . 2012 Feb1;13(2):150-156
33. Jae-Hoon Choi, Ji-Young Yoo, Sun-Ok Kim, Sung-Eun Yoo, Goo Taeg Oh * . KR-31543 reduces the production of proinflammatory molecules in human endothelial cells and monocytes and attenuates atherosclerosis in mouse model. Exp Mol Med.
2012 Dec
31;44(12):733-739
4

34. In-Hyuk Jung, You-Han Lee, Ji-Young Yoo, Se-Jin Jeong, Seong Keun Sonn, Jong-Gil
Park, Keun Ho Ryu, Bong Yong Lee, Hye Young Han, So Young Lee, Dae-Yong Kim,
Hang Lee, Goo Taeg Oh * . Ginkgo bilobaExtract(GbE) Enhances the Anti-atherogenic
Effect of Cilostazol by Inhibiting ROS Generation. Exp Mol Med . 2012 May
31;44(5):311-318
35. Jae-Hoon Choi, Cheolho Cheong, Durga B Dandamudi, Chae Gyu Park, Anthony Rodrig uez, Saurabh Mehandru, Klara Velinzon, In-Hyuk Jung, Ji-Young Yoo, Goo Taeg Oh * , R alph M. Steinman * . Flt3 signaling-dependent dendritic cells protect against atherosclero sis. Immunity 2011 Nov23;35(5):819-831 *(Co-corresponding Author)
36. Jong-Gil Park, Ji-Young Yoo, Se-Jin Jeong, Jae-Hoon Choi, Mi-Ran Lee, Mi-Ni Lee,Jeo ng Hwa Lee, Hyoung Chin Kim, Hanjoong Jo, Dae-Yeul Yu, Sang Won Kang, Sue Goo
Rhee, Mun-Han Lee, Goo Taeg Oh * . Peroxiredoxin2 deficiency exacerbates atheroscler osis in apolipoproteinE-deficientmice. Circulation Research 2011 Sep16;109(7):739-7
49
37. Ga Young Lee, Jong-Ho Kim, Goo Taeg Oh, Byung-Heon Lee, Ick Chan Kwon,In-
San Kim. Molecular targeting of atherosclerotic plaques by a stabilin-2specific peptide ligand. J Control Release 2011 Oct 30;155(2):211-217
38. Seung-Soon Im, Mi-Young Kim, Sool-Ki Kwon, Tae-Hyun Kim, Jin-Sik Bae, Hail Kim, Ky ung-Sup Kim, Goo-Taeg Oh, Yong-Ho Ahn. Peroxisome proliferator-activated receptor
{alpha}is responsible for the up-regulation of hepatic glucose-6-phosphatase gene expr ession in fasting and db/db Mice. The Journal of Biological Chemistry 2011 Jan 14;2
86(2):1157-1164
39. Seongkeun Sonn, Goo Taeg Oh, Kunsoo Rhee. Nek2 and Its Substrate, Centrobin/Nip2,
are Required for Proper Meiotic Spindle Formation of the Mouse Oocytes. Zygote 201
1 Feb;19(1):15-20
40. Jong Gil Park, Goo Taeg Oh * . The role of peroxidases in the pathogenesis of atheroscle rosis. BMB Reports . 2011 Aug;44(8):497-505
41. Jae-Hoon Choi, Jong-Gil Park, Hyung Jun Jeon, Mi-Sun Kim, Mi-Ran Lee, Mi-Ni Lee, Se ong Keun Sonn, Jae-Hong Kim, Mun Han Lee, Myung-Sook Choi, Yong Bok Park, Oh-
Seung Kwon, Tae-Sook Jeong, Woo Song Lee, Hyun Bo Shim, Dong Hae Shin, Goo T aeg Oh * . 5-(4-Hydroxy-2,3,5-trimethylbenzylidene) thiazolidine-2,4-dione attenuates ath erosclerosis possibly by reducing monocyte recruitment to the lesion. Exp Mol Med. 20
11 Aug 31;43(8):471-478
42. Ji Hae Seo, Jong-Ho Cha, Ji-Hyeon Park, Chul-Ho Jeong, Zee-Yong Park, Hye-Suk Lee,
Seung Hyun Oh, Ju-Hee Kang, Se Won Suh, Kyoung Hoon Kim, Jun Yong Ha, Sang H ee Han, Se-Hee Kim, Ji-Won Lee, Jeong Ae Park, Joo-Won Jeong, Kong-Joo Lee, Goo
Taeg Oh, Mi-Ni Lee, Sung Won Kwon, Seung-Ki Lee, Kwang-Hoon Chun, Su-Jae Lee,
Kyu-Won Kim. Arrest Defective 1 Autoacetylation Is a Critical Step in Its Ability to Stimul ate Cancer Cell Proliferation. Cancer Research 2010 Jun;70(11):4422-4432
43. Jae-Hoon Chio, Hyung Jun Jeon, Jong-Gil Park, Seong Keun Sonn, Mi-Ran Lee, Mi-Ni L ee, Hye Jin You, Geun-Young Kim, Jae-Hong Kim, Mun Han Lee, Oh-Seung Kwon, Ki-H oan Nam, Hyoung-Chin Kim, Tae-Sook Jeong, Woo Song Lee, Goo Taeg Oh * . Anti-ather ogenic effect of BHB-TZD having inhibitory activities on cyclooxygenase and 5-lipoxygen ase in hyperlipidemic mice. Atherosclerosis 2010 Sep;212(1):146-152
44. Vu Thi Thu, Hyoung Kyu Kim, Seung Hee Ha, Ji-Young Yoo, Won Sun Park, Nari Kim,
Goo Taeg Oh, Jin Han. Glutathione peroxidase 1 protects mitochondria against hypoxia/r eoxygenation damage in mouse hearts. Pflugers Archiv European Journal of Physiolo gy.
2010 Jun;460(1):55-68
45. Hyung Jun Jeon, Jae-Hoon Choi, Inhyuk Jung, Jong Gil Park, Mi Ran Lee, Mi Ni Lee, Bor a Kim, Ji Young Yoo, Se-Jin Jeong, Dae-Yong Kim, Jeong-Euy Park, Hyun-Young Park, K
5

yu Bum Kwack, Boem Kyu Choi, Byung Se Kwon, Goo Taeg Oh * . CD137(4-1BB) Deficien cy Reduces Atherosclerosis in Hyperlipidemic Mice. Circulation 2010 Mar9;121(9):1124-
1133
46. Mi-Ni Lee, Shi-Nai Lee, Se-Hee Kim, Bo Ra Kim, Bo-Kung Jung, Ji Hae Seo, Jae-Hoon C hoi, Sun Hee Yim, Mi-Ran Lee, Jong-Gil Park, Ji-Young Yoo, Jeong Hun Kim, Seung-Tae k Lee, Hwan-Mook Kim, Sandra Ryeom, Kyu-Won Kim *
, , Goo Taeg Oh * . Roles of Arrest-D efective Protein1 225 and Hypoxia-Inducible Factor1{alpha} in Tumor Growth and Metastasi s. J Natl Cancer Inst. 2010 Mar17;102(6):426-442 *(Co-corresponding Author)
47. Hyung Jun Jeon, Jae-Hoon Choi, Inhyuk Jung, Jong Gil Park, Mi Ran Lee, Mi Ni Lee, Bor a Kim, Ji Young Yoo, Se-Jin Jeong, Dae-Yong Kim, Jeong-Euy Park, Hyun-Young Park, K yuBum Kwack, Boem Kyu Choi, Byung Se Kwon, Goo Taeg Oh * . CD137(4-1BB) Deficienc y Reduces Atherosclerosis in Hyperlipidemic Mice. Circulation.
2010 Mar 9;121(9):1124-
33
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