Professor of Medicinal Chemistry
Egyptian
03.05.1951 (Sohag/Egypt)
: Married
th
1) Ph. D. Pharm. Sciences (Pharm. Chemistry) Bonn University (1987):
“Die Asymmetrische Synthese von GABA-verwandeter Cycloaliphatisher
Aminosauren und bicyclishe Lactame”
2) M.Sc. Pharm. Chem. (Assiut University; May 1979):
“Synthesis of Some Nitrobenzimidazole Acrylic Acid Derivatives of potential
Antiparasitic Activity”.
3) B.Sc. Pharm. Sci. (Assiut university; June 1974).
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1) Head of the dept. and Prof. of Pharmaceutical Chemistry, Faculty of Pharmacy; 6 th
October
University (Oct. 2013).
2) Professor of medicinal chemistry, Faculty of Pharmacy; Nahda University; Beni Suef
(Jan. 2012 – June 2013)
3) Head of the Department of Medicinal Chemistry; Faculty of Pharmacy; Assiut
Universty (Sept. 1999 – Oct. 2000; Oct. 2010 – Jul. 2011).

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4) Coordinator of the department of Pharmaceutical chemistry, College of Pharmacy,
King Khalid University (October 2007 – July 2010).
5) Professor of medicinal Chemistry, King Khalid University, Abha/kingdom of Saudi
Arabia (October 2005 – July 2010).
6) Professor of medicinal chemistry, Addis Ababa University, Addis Ababa/ Ethiopia
(October 2004 – July 2005).
7) Vice Dean of Faculty of Pharmacy/ Assiut University (for students and education
affairs (Oct. 2000 – Oct. 2004).
8) Director of the Center for Drug Discovery/Assiut University (Nov. 1999 – Oct. 2004).
9) Professor of Medicinal Chemistry (September 1999).
10) Associate Professor of Pharm. Chem. (June 1994)
11) Research fellowship: Center for drug Discovery; Faculty of Pharmacy; Florida
University; Gainsville/Florida; USA 1992.
12) Lecturer of Pharmaceutical Chemistry (June 1987); Dept. of Pharmaceutical
Chemistry; Faculty of Pharmacy, Assiut University.
of Pharmaceutical Chemistry (June 1979); Dept. of
Pharmaceutical Chemistry; Faculty of Pharmacy, Assiut University.
14) Demonstrator of Pharmaceutical Chemistry (Sept 1974)); Dept. of Pharmaceutical
Chemistry; Faculty of Pharmacy, Assiut University.
1) Member of the referee of the scientific committee for promotion of professor and associate
professors (Pharmaceutical Chemistry) 2013 - 2015.
2) Reviewer in several Journals and Bulletins:
- Bulletin of Pharmaceutical Sciences; Assiut University.
- Journal of Pharmaceutical Sciences, Cairo University.
- Al-Mansoura University Scientific Award.
- Saudi Pharmaceutical Journal.
- Spectrochimica Act Part A: Biomolecular Spectroscopy.
- King AbdulAziz University; Deanship of Scientific Research.
- Portugese Foundation for Science and Technology.
3) Coordinator of the following committees of faculty of pharmacy – King Khalid
university; Abha/Saudi Arabia:

3 a) Committee of training program for graduated pharmacists. b) Committee of the study plan and courses. c) Committee of Academic Accreditation and Quality Assessment.
4) Member of the Egyptian Pharmacist Syndicate
5) Member of the Egyptian Pharmaceutical Society.
6) Member of the Egyptian Society for Electron Microscopy.
7) Member of the New York Academy of Science.
1) 1 st
Scientific Conference; Faculty of Pharmacy – October 6 th
University. Dec. 5 th
2013.
2) Workshop on Computer-aided drug Design, Dept. of medicinal Chemistry; faculty
of Pharmacy; Assiut University (Jan. 26 th
– 28 th
2013).
3) Training programs on “E-Learning” King Khalid university; Abha/Saudi Arabia (2009).
4) Training program on” Academic leadership” 1 – 3 Nov. 2009; Abha/ Saudi Arabia.
5) The 7 th
International Saudi Pharmaceutical Conference; 19-21 March (2007); Riyadh, Saudi Arabia
6) Workshop on “ Conducting Initial Quality Evaluation ” 17 th
April 2007; Centre for
academic Assessment and Development; KKU; Abha/ Saudi Arabia.
7) Workshop on “ Multiple Choice Questions ” 19 th
April 2007; Medical Education
Development Centter (MEDC); Abha/Saudi Arabia.
8) Assiut University 4 th
International Conference of Pharmaceutical Sciences, Assiut/Egypt
March 4 – 5 (2004).
9) Symposium on"Red Sea Marine plants as Natural Leads for new Drugs". Faculty of
Pharmacy, Suez canal University, Ismailia/Egypt Dec. 3 – 5 (2003).
10) Assiut University 3 rd
International Conference of Pharmaceutical Sciences, Assiut/Egypt
March 4 – 5 (2002).
11) Assiut University 2 nd
International Conference of Pharmaceutical Sciences, Assiut/
Egypt March 2- 4 (1998).
12) XIV Wissenschaftliche Tagung der Oesterreichischen Pharmazeutischen Gesellschaft,
Graz/Austeria June 11 – 13 (1998).
13) Assiut University 1 st
International Conferenc of Pharmaceutical Sciences, Assiut/Egypt
March 4 – 5 (1998).
14) Training Courses in Molecular Biology, Molecular biology and genetic engineering
center, Assiut University, Assiut/Egypt May, 3 – 6 (1997).

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15) Workshop on Environmental Pollution and health problems, Faculty of Medicine/Assiut
University, Assiut/Egypt, May 18 – 23 (1996).
16) Training courses on Electron microscopy (Technique and Applications), Assiut
University, Assiut/Egypt March 30 – April 4 (1996).
17) Symposium on "Antioxidants in medical practice" faculty of Medicine, Assiut
University, Assiut/Egypt Nov. 5 th
(1996).
18) Egyptian-German Conference on Medicinal Plants, Assiut/Egypt Nov. 27(1995).
19) XXIV Conference of pharmaceutical Sciences, The Egyptian Pharmaceutical Society,
Cairo/Egypt Dec. 22 – 24 (1994).
20) Conference of pharmaceutical Sciences, The Egyptian Pharm. Society, Cairo/Egypt
Dec. 17 – 19 (1991).
21) Conference of the American Chemical Society, Chicago, USA, Feb. 1992. XXII
22) Symbosium on" Naturstufe als Leitsubstanzen fuer neue Arzneistufe" Deutsche
Pharmazeutische Gesellschaft, Bonn/Germany 18 -19 March 1988.
Teaching of the different topics of Medicinal chemistry for the graduate and postgraduate students in the Faculties of Pharmacy, Assiut University, Tanta University (1999/2000), and
Al-Azhar University (Assiut), Addis Ababa University/ Ethiopia, and King Khaled
University, Abha/KSA.
Good experience in applications and teaching medicinal Chemistry through E-Learning.
The teaching courses include the following topics:
1) Medicinal Chemistry:
Chemotherapeutic agents, Analgesics and Antiinflammatory drugs, GIT drugs,
Hormones and Vitamins, CNS drugs, Drugs affecting the autonomic nervous system,
Cardiovascular drugs, Diuretics, Local and general anesthetics, Antihistaminics,
Diaggnostic agents, Pharmaceutical aids, Drugs, Metabolism, Drug design,
Biotechnology drugs.
2) Drug Design and drug Development.
3) Pharmaceutical Organic chemistry:
Structure and properties of organic compounds, mechanism of organic reactions,
stereochemistry, spectroscopic characteristics of organic molecules, structure
elucidation of organic molecules using: (UV; IR, NMR, and MS).

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4) Pharmaceutical Analytical Chemistry.
5) Instrumental Analysis.
6) Quality assurance and quality control of medicines.
7) Postgraduate courses
1) Designing organic synthesis.
2) Reaction mechanisms in organic synthesis.
3) Combinatorial chemistry.
4) Advanced NMR methods in structure elucidation.
5) Biochemical basis of drugs actions.
6) Drug Design
7) Chemical Aspects in Quality Assurance of Drugs.
1) Pharmaceutical Chemistry I and II (October 6 University) 2013/2014.
2) Practical Pharmaceutical Chemistry I & II (October 6 University) 2013/2014.
3) Topics in Medicinal Chemistry vol. I and II (Assiut University) 2011/2012.
4) Practical Pharmaceutical Chemistry vol. I and II (Assiut University) 2011/2012.
5) Review Article on "Recombinant DNA Technology in Drug Discovery", Assiut University
September 1999.
6) Review Article on "Peptidomimetics and their Applications in Drug Design" Assiut
University September, September 2001.
1) Drug Design
2) Asymmetric Synthesis of biologically active substances
3) Design and synthesis of Prodrugs of Non-Steroidal anti-inflammatory agents with improved therapeutic index.
4) Synthesis and Design of biologically active compounds including: NSAIDs; Antiparasitic
agents; Antifungal agents.
5) Pharmacokinetic studies using HPLC.
6) Design and Synthesis of Dopamine Chemical Delivery system to the brain.
7) Design and synthesis of Cytrabine (Ara-C) prodrugs.
8) Quantitative-Structure Activity Relationship Studies of newly synthesized antitubercular agents.

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Design, Synthesis and Molecular Modeling study of 2-Substitutedimino-5-Arylidene-4thiazolidinone derivatives as non-nucleoside inhibitors of Hepatitis C Virus (HCV) NS5B
Polymerase (M. Sc. Thesis October 6/Cairo university 2014)
2) Synthesis and molecular modeling studies of some Naphthyridine derivatives as Bedaquiline analogs with potential anti-tuberculosis activity. (M.Sc. Thesis Asyut Univ. 2013)
3) Design Synthesis and Molecular Modelling study of some 1,8 Naphthyridine derivatives as potential antitubercular agents. (M. Sc thesis, Assiut Univ. 2012).
4) Design Synthesis and Molecular Modelling study of some isoxazole derivatives as potential antitumor agents. (M. Sc thesis, Assiut University 2010).
5) Biotransformation studies of prednisone and prednisolone using human intestinal bacteria.
(M. Sc thesis, Assiut University 2006).
6) Assessment on the quality and Influence of the tropical storage conditions on certain
amoxicillin formulations marketed in ethiopia. (M. Sc thesis, Addis Ababa University 2005)
7) Comparative in vitro evaluation of antihypertensive drugs (Methyldopa, Furosemide, and
propranolo) from local market, Addis Ababa. (M. Sc thesis, Addis Ababa University 2005)
8) Comparative in vitro quality evaluation of tablets of commonly prescribed antiepileptic
drugs, carbamazepine and phenobarbital, from drug retail outlets in Addis Ababa.
(M. Sc thesis, Addis Ababa University 2005)
9) Design and synthesis of some p-substituted styrylisoxazole carboxylic acid derivatives as
antiinflammatory agents. (M. Sc thesis, Assiut University 2004)
10) Synthesis and antibacterial activity of some 2,5,7-triazolo[1,5-a]pyrimidines (M. Sc thesis, Assiut University 2002)
11) Design, synthesis and antidepressant activity of Some N
2
-substituted nalidixic acid hydrazides
and their cyclized Analogues. (M. Sc thesis, Assiut University 1998)
12) Synthesis and investigation N
4
-substituted cytarabine derivatives as prodrugs.
(Ph. D thesis, Assiut University 1994)
1) S ynthesis of New 1,3-Benzodiazine and 1,3,4-Benzotriazeine Derivatives for biological
Study
"
(M.Sc. Zagazig University; 2014).
2) Synthesis, Docking and Biological Evaluation of Some Novel Quinaoxaline Compounds.
(M.Sc. Thesis, Alazhar University. (Girls branch); 2012)

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3) Synthesis of Novel Triazole/oxime hybrids as nitric oxide Donors with potential
anticancer and anti-inflammatory activities. (M.Sc. thesis, Minia. University 2012).
4) Computer-Based Drug Design and Synthesis of Various Thiazole Derivatives Having
Potential Anti-HCV Activity. (Ph. D. thesis, Ain Shams University 2011).
5) Design and Synthesis of certain Aryloxy Cycloalkane carboxamides as anticnvulsants.
(M.Sc. thesis, Ain Shams University 2011)
6) Synthesis of somw shiff’s bases of indoline-2,3-dione and quinoline carboxylic acid
derivatives with potential antitubercular activity. (M.Sc. thesis, Knig Saud University 2010)
7) Descriptive quantitative structure-radical scavenging activity relationship study of flavonoids.
(M. Sc thesis, Addis Ababa University 2005)
8) Stress decomposition studies and development of validated stability indicating assay method
for lamivudine. (M. Sc. thesis, Addis Ababa University 2005)
9) Biotransformation studies of prednisone and prednisolone using human intestinal bacteria.
(M. Sc thesis, Assiut University 2006)
10) Assessment on the quality and influence of the tropical storage conditions on certain
amoxicillin formulations marketed in Ethiopia. (M. Sc thesis, Addis Ababa University 2005)
11) Comparative in vitro evaluation of antihypertensive drugs (Methyldopa, Furosemide, and
propranolo) from local market, Addis Ababa. (M. Sc thesis, Addis Ababa University 2005)
12) Comparative in vitro quality Evaluation of tablets of commonly prescribed antiepileptic
drugs, carbamazepine and phenobarbital, from drug retail outlets in Addis Ababa.
(M. Sc thesis, Addis Ababa University 2005)
13) Design and synthesis of some p-substituted styrylisoxazole carboxylic Acid derivatives as
antiinflammatory agents. (M. Sc thesis, Assiut University 2004)
14) Synthesis and antibacterial activity of some 2,5,7-triazolo[1,5-a]pyrimidines
(M. Sc thesis, Assiut University 2002)
15) Design, synthesis and antidepressant activity of some N
2
-substituted nalidixic acid hydrazides and their cyclized analogues. (M. Sc thesis, Assiut University 1998)
16) Synthesis and investigation N
4
-substituted cytarabine derivatives as prodrugs. (Ph. D thesis, Assiut University 1994)
17) Synthesis, antihypertensive and antibacterial activity of some thiazolo- and imidazo-
pyrimidines. (M. Sc thesis, Al-Azhar University 2004).
18) Design and synthesis of some triazolquinazolines as antibacterial and anti-inflammatory
agents. (Ph. D thesis, Cairo University 2001).

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1 Biotransformation studies of prednisone using human intestinal bacteria; Part II:
Anaerobic incubation and docking studies.
Mohamed M. Al-Sanea, Atef A. Abdel-Hafe z, Farghaly A. Omar and Adel F. Youssef
Journal of Enzyme Inhibition and Medicinal Chemistry, 2009, 1-9
2-
Mohammed M. Al-Sanea, Atef A. Abdel-Hafez, Farghaly A. Omar and Adel F.
Youssef. Bull. Pharm. Sci., Assiut University, Vol. 31, Part 2, 2008, pp. 215-228 .
3- Design and Synthesis of some p-Substituted Styrylisoxazole Carboxylic Acid Derivatives as
Antiinflammatory Agents.
Farghaly A. Omar
1
, Atef A. Abdel-Hafez, and Montaser S. Bull. Pharm. Sci.
Assiut University, 27 , 171-186(2004).
4- Synthesis and antibacterial screening of Some 2,5,7-Triaryl-1,2,4-Triazol[1,5-a] pyrimidines.
Farghaly A. Omar
1
, Nawal A. El-Koussi
1
, Mohamed F. Radwan
2
and Salah A.
Abdel-Aziz
3
.
Bull. Pharm. Sci. Assiut University, 27 , 141-154(2004).
5- Cyclic Amide Derivatives as Potential Prodrugs: N-Hydroxymethyl-succinimide-/isatin Esters
of some Non-steroidal Anti-inflammatory Carboxylic Acids as Prodrugs with Improved
Therapeutic Index
Nadia M. Mahfouz, Farghaly A. Omar and Tarek A. Fadl. Eur. J. Med. Chem.
34 ,551 - 562(1999).
6- Synthesis and in vitro antifungal activity of some N,N-disubstituted dithiocarbamic acid
esters derived from 2-methylquinazolinones.
Farghaly A. Omar and Ahmed M. Moharram. Boll. Chim. Farmaceutico 138 , 273 –
282(1999)
7- Syntesis of Some 6-Bromo Nalidixic Acid Hydrazides As potential Antidepressants.
A.F. Youssef , Farghaly A. Omar, H.A. El-Sherief and G.A. Ahmad, Proceedings of Assiut
Univ. 1 st
Pharm. Sci. Conf. 20 - 34(1998).

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8- Design, Synthesis and Antidepressant Activity of Some N
2
-substituted Nalidixic Acid
Hydrazides and their Cyclized Analogues A.F. Youssef , Farghaly A. Omar,
H.A. El-sherief and G.A. Abou-Rahma. Bull. Pharm. Sci., Assiut University, 21 ,15 -26(1998).
9- Molecular Structural Parameters in Tuberculostatic Activity of Polyhydroxyxanthones.
Hassan H. Farag , Farghaly A. Omar and Nadia M. Mahfouz. Bull. Pharm. Sci., Assiut
University, 21 ,7 - 14(1998).
10- Paracetamol (Acetaminophen) Esters of Some Non-steroidal Anti-inflammatory
Carboxylic Acids as Mutual Prodrugs with Improved Therapeutic Index
T. A. Fadl and F. A. Omar. J. Inflammopharmacolgy, 6 (2), 143-157(1998).
11- Cyclic amide derivatives as potentialpProdrugs: Synthesis and evaluation of N -hydroxy-
methylphthalimide esters of some non-steroidal anti-inflammatory carboxylic acid drugs
Farghaly A. Omar. Eur. J. Med. Chem. 33 , 123-131(1998)
12- Design, Synthesis and Anti-inflammatory Activity of Some1,3,4-Oxadiazole Derivatives
F.A. Omar, N.M. Mahfouz and M.A. Rahman. Eur. J. Med. Chem . 31 , 819-825(1996)
13- Steric Parameters in PLE Catalyzed Hydrolysis of N
4
-Substitued Cytarabine ester prodrugs
T. Kawaguchi, A.F. Youssef, T.A. Fadl , F.A. Omar, H.H. Farag and T.Hasegawa,
Pharmazie 51 , 718(1996)
14- Synthesis and Investigation of N
4
-Substituted Cytarabine Derivatives as Prodrugs
T.A. Fadl, T. Hasegawa, A.F. Youssef, H.H. Farag , F.A. Omar and T. Kawaguchi
Pharmazie 50 , 382-387(1995)
15- Spectrophotometric Determination of Piroxicam Using 2,2-Diphenyl-1-Picrylhydrazyl
Kamla M. Emara and Farghaly A. Omar. Alex. J. Pharm. Sci. 8 , 24-28(1994)
16- Synthesis of Some Nalidixic Acid Derivatives. Farghaly A. Omar, Alex. J. Pharm. Sci .
8 , 65-68(1994)
17- Synthesis and Evaluation of Redox Chemical Delivery System for Brain Enhanced
Dopamine Containing an Activated Carbamate-type Ester.
Farghaly A. Omar, Hassan H. Farag and N. Bodor. J. Drug Targeting 2 ,309-316(1994)
18- Improved Delivery through Biological Membranes: Preparation and Investigation of
Stable Dopamine Chemical Delivery System Samples.
N. Bodor, Hassan H. Farag and
Farghaly A. Omar. Bull. Pharm. Sci., Assiut University, 16 , 175-182(1993)
19- Niridazole Prodrugs: Synthesis, Characterization and Hydrolysis Kinetics of some
N-Acyloxymethyl Niridazoles
Farghaly A. Omar; Nadia M. Mahfouz; Hassan H. Farag and Saleh I. Saleh

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Saudi Pharmaceutical Journal, 1 , 62-69(1993)
20- Preparation and Evaluation of isoniazid Microcapsules
S.M. Safwat and Farghaly A. Omar. S.T.P. Pharma Sciences 3 ,398-403(1993)
21- Synthesis and Antibacterial Activity of Certain Quinoline and Quinazoline Derivatives
Containing Sulfide and Sulfone Moieties
Maher F. Elzohry; Abdel-Hameed N. Ahmed ; Faghaly A. Omar and Mohamed A.
Abd-Alla. J. Chem. Tech. and Biotecnol. 53 ,329-336(1992)
22- EPC-Synthese cis-Bicyclischer Lactame und Amine
Farghaly Omar und August W. Frahm. Arch. Pharm. (Weinheim) 323 , 923-928(1990)
23- Die Asymmetrische Synthese von GABA-verwandter Cycloaliphatischer Aminosauren
Farghaly Omar und August W. Frahm. Arch. Pharm. (Weinheim) 322 , 461-471(1989)
24- Die Asymmetrische Synthese der cis 4aR,8aR- und cis-4aS,8aS-Dekahydrochinoline
Farghaly Omar und August W. Frahm. Arch. Pharm. (Weinheim) 321 , 111-114(1988)
25- Synthesis of 3-(1-Methyl-5-nitro-benzimidazolyl)acrylic acid Derivatives as expected
Antischistosomal Agents.
Nabil M. Omar; Hassan H. Farag and Farghaly A. Omar. Z. Naturforsch 84b , 1427-
1430(1979)