Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
Group
Volume
Year1
000075-07-0 Acetaldehyde associated with consumption of alcoholic
beverages
Acheson process, occupational exposure associated with
1
100E
2012
1
111
Acid mists, strong inorganic
001402-68-2 Aflatoxins
Alcoholic beverages
Aluminium production
1
1
1
1
000092-67-1 4-Aminobiphenyl
1
Areca nut
000313-67-7 Aristolochic acid
(NB: Overall evaluation upgraded to Group 1 based on
mechanistic and other relevant data)
000313-67-7 Aristolochic acid, plants containing
007440-38-2 Arsenic and inorganic arsenic compounds
1
1
54, 100F
56, 82, 100F
44, 96, 100E
34, Sup 7,
100F
1, Sup 7, 99,
100F
85, 100E
82, 100A
In
prep.
2012
2012
2012
2012
001332-21-4 Asbestos (all forms, including actinolite, amosite,
77536-67-5* anthophyllite, chrysotile, crocidolite, tremolite)
(NB: Mineral substances (e.g. talc or vermiculite) that
012172-73-5
contain asbestos should also be regarded as
77536-66-4* carcinogenic to humans.)
012001-29-5 *The presence of an asterisk indicates that the
012001-28-4 registration is for a substance which CAS does not treat
in its regular CA index
1
1
1
2012
2012
2012
82, 100A
23, Sup 7,
100C
14, Sup 7,
100C
2012
2012
2012
2012
77536-68-6*
Auramine production
1
000446-86-6 Azathioprine
1
000071-43-2 Benzene
1
000092-87-5 Benzidine
1
Benzidine, dyes metabolized to
(NB: Overall evaluation upgraded to Group 1 based on
mechanistic and other relevant data)
000050-32-8 Benzo[a]pyrene
(NB: Overall evaluation upgraded to Group 1 based on
mechanistic and other relevant data)
007440-41-7 Beryllium and beryllium compounds
Betel quid with tobacco
1
Sup 7, 99,
100F
26, Sup 7,
100A
29, Sup 7.
100F
29, Sup 7,
99, 100F
99, 100F
1
92, 100F
2012
1
1
58, 100C
85, 100E
2012
2012
1
2012
2012
2012
2012
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
Group
Volume
Year1
Betel quid without tobacco
000542-88-1 Bis(chloromethyl)ether; chloromethyl methyl ether
000107-30-2 (technical-grade)
1
1
85, 100E
4, Sup 7,
100F
2012
2012
000055-98-1 Busulfan
1
2012
000106-99-0 1,3-Butadiene
007440-43-9 Cadmium and cadmium compounds
000305-03-3 Chlorambucil
1
1
1
000494-03-1 Chlornaphazine
1
018540-29-9 Chromium (VI) compounds
Clonorchis sinensis (infection with)
Coal, indoor emissions from household combustion of
Coal gasification
008007-45-2 Coal-tar distillation
065996-93-2 Coal-tar pitch
1
1
1
1
1
1
Coke production
000050-18-0 Cyclophosphamide
006055-19-2
059865-13-3 Cyclosporine (see ciclosporin)
079217-60-0
000078-87-5 1,2-Dichloropropane
1
1
4, Sup 7,
100A
97, 100F
58, 100C
26, Sup 7,
100A
4, Sup 7,
100A
49, 100C
61, 100B
95, 100E
92, 100F
92, 100F
35, Sup 7,
100F
92, 100F
26, Sup 7,
100A
1
000056-53-1 Diethylstilbestrol
1
Engine exhaust, diesel
Epstein-Barr virus
066733-21-9 Erionite
1
1
1
Estrogen-only menopausal therapy
Estrogen therapy, postmenopausal (see Estrogen-only
menopausal therapy)
Estrogen-progestogen menopausal therapy (combined)
Estrogen-progestogen oral contraceptives (combined)
(NB: There is also convincing evidence in humans that
these agents confer a protective effect against cancer in
the endometrium and ovary)
2
2012
2012
2012
2012
2012
2012
2012
2012
2012
2012
2012
2012
41, Sup 7,
71, 110
21, Sup 7,
100A
In
prep.
2012
2013
2012
2012
1
46, 105
70, 100B
42, Sup 7,
100C
72, 100A
1
1
72, 91, 100A
72, 91, 100A
2012
2012
2012
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
Group
Volume
Year1
000064-17-5 Ethanol in alcoholic beverages
000075-21-8 Ethylene oxide
(NB: Overall evaluation upgraded to Group 1 based on
mechanistic and other relevant data)
033419-42-0 Etoposide
(NB: Overall evaluation upgraded to Group 1 based on
mechanistic and other relevant data)
033419-42-0 Etoposide in combination with cisplatin and bleomycin
015663-27-1
011056-06-7
Fission products, including strontium-90
Fluoro-edenite fibrous amphibole
1
1
96, 100E
97, 100F
2012
2012
1
76, 100A
2012
1
76, 100A
2012
1
1
100D
111
000050-00-0 Formaldehyde
Haematite mining (underground)
1
1
88, 100F
1, Sup 7,
100D
61, 100B
59, 100B
59, 100B
67, 100B
64, 90, 100B
2012
In
prep.
2012
2012
Helicobacter pylori (infection with)
Hepatitis B virus (chronic infection with)
Hepatitis C virus (chronic infection with)
Human immunodeficiency virus type 1 (infection with)
Human papillomavirus types 16, 18, 31, 33, 35, 39, 45,
51, 52, 56, 58, 59
(NB: The HPV types that have been classified as
carcinogenic to humans can differ by an order of
magnitude in risk for cervical cancer)
Human T-cell lymphotropic virus type I
Ionizing radiation (all types)
Iron and steel founding (occupational exposure during)
1
1
1
1
1
Isopropyl alcohol manufacture using strong acids
Kaposi sarcoma herpesvirus
Leather dust
000058-89-9 Lindane (see also Hexachlorocyclohexanes)
1
1
1
1
67, 100B
100D
34, Sup 7,
100F
Sup 7, 100F
70, 100B
100C
113
Magenta production
Meat, processed (see Processed meat)
000148-82-3 Melphalan
1
57, 99, 100F
1
9, Sup 7,
100A
24, Sup 7,
100A
Sup 7, 100A
000298-81-7 Methoxsalen (8-methoxypsoralen) plus ultraviolet A
radiation
013909-09-6 Methyl-CCNU
3
1
1
1
1
1
2012
2012
2012
2012
2012
2012
2012
2012
2012
2012
2012
In
prep.
2012
2012
2012
2012
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
Group
000101-14-4 4,4'-Methylenebis(2-chloroaniline) (MOCA)
(NB: Overall evaluation upgraded to Group 1 based on
mechanistic and other relevant data)
Mineral oils, untreated or mildly treated
MOPP and other combined chemotherapy including
alkylating agents
000091-59-8 2-Naphthylamine
016543-55-8
064091-91-4
057465-28-8
057117-31-4
000062-44-2
Neutron radiation
(NB: Overall evaluation upgraded to Group 1 with
supporting evidence from other relevant data)
Nickel compounds
N'-Nitrosonornicotine (NNN) and 4-(NNitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK)
(NB: Overall evaluation upgraded to Group 1 based on
mechanistic and other relevant data)
Opisthorchis viverrini (infection with)
Outdoor air pollution
Outdoor air pollution, particulate matter in
Painter (occupational exposure as a)
Particulate matter in outdoor air pollution (see Outdoor air
pollution, particulate matter in)
3,4,5,3’,4’-Pentachlorobiphenyl (PCB-126)
(see Polychlorinated biphenyls, dioxin-like, with a TEF
according to WHO)
2,3,4,7,8-Pentachlorodibenzofuran
(NB: Overall evaluation upgraded to Group 1 based on
mechanistic and other relevant data)
Phenacetin
Phenacetin, analgesic mixtures containing
014596-37-3 Phosphorus-32, as phosphate
007440-07-5 Plutonium
001336-36-3 Polychlorinated biphenyls
Polychlorinated biphenyls, dioxin-like, with a Toxicity
Equivalency Factor (TEF) according to WHO (PCBs 77,
81, 105, 114, 118, 123, 126, 156, 157, 167, 169, 189)
(NB: Overall evaluation upgraded to Group 1 with
strong supporting evidence from other relevant data)
Processed meat (consumption of)
4
Volume
Year1
1
57, 99, 100F
2012
1
33, Sup 7,
100F
Sup 7, 100A
2012
2012
1
4, Sup 7, 99,
100F
75, 100D
1
1
49, 100C
89, 100E
2012
2012
1
1
1
1
61, 100B
109
109
47, 98, 100F
2012
2016
2016
2012
1
100F
2012
1
100F
2012
1
2012
1
24, Sup 7,
100A
Sup 7, 100A
78, 100D
78, 100D
18, Sup 7,
107
107
1
114
1
1
1
1
1
1
2012
2012
2012
2012
2012
2016
2016
In
prep.
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
013233-32-4
013982-63-3
015262-20-1
010043-92-2
Agent
Group
Radioiodines, including iodine-131
Radionuclides, alpha-particle-emitting, internally
deposited
(NB: Specific radionuclides for which there is sufficient
evidence in humans are also listed individually as
Group 1 agents)
Radionuclides, beta-particle-emitting, internally deposited
(NB: Specific radionuclides for which there is sufficient
evidence in humans are also listed individually as
Group 1 agents)
Radium-224 and its decay products
Radium-226 and its decay products
Radium-228 and its decay products
Radon-222 and its decay products
Rubber manufacturing industry
Salted fish, Chinese-style
Schistosoma haematobium (infection with)
013909-09-6 Semustine (see Methyl-CCNU)
068308-34-9 Shale oils
014808-60-7 Silica dust, crystalline, in the form of quartz or cristobalite
Solar radiation
Soot (as found in occupational exposure of chimney
sweeps)
000505-60-2 Sulfur mustard
Year1
1
1
78, 100D
78, 100D
2012
2012
1
78, 100D
2012
1
1
1
1
1
78, 100D
78, 100D
78, 100D
43, 78, 100D
28, Sup 7,
100F
56, 100E
61, 100B
2012
2012
2012
2012
2012
35, Sup 7,
100F
68, 100C
55, 100D
35, Sup 7,
100F
9, Sup 7,
100F
66, 100A
2012
1
1
1
1
1
1
1
1
010540-29-1 Tamoxifen
(NB: There is also conclusive evidence that tamoxifen
reduces the risk of contralateral breast cancer in breast
cancer patients)
001746-01-6 2,3,7,8-Tetrachlorodibenzo-para-dioxin
000052-24-4 Thiotepa
007440-29-1 Thorium-232 and its decay products
Tobacco, smokeless
Tobacco smoke, second-hand
Tobacco smoking
000095-53-4 ortho-Toluidine
000299-75-2 Treosulfan
1
1
1
1
1
1
1
1
000079-01-6 Trichloroethylene
1
5
Volume
69, 100F
50, 100A
78, 100D
89, 100E
83, 100E
83, 100E
77, 99, 100F
26, Sup 7,
100A
63, 106
2012
2012
2012
2012
2012
2012
2012
2012
2012
2012
2012
2012
2012
2012
2012
2014
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
000075-01-4
000079-06-1
023214-92-8
000320-67-2
000154-93-8
064742-93-4
002425-06-1
000075-87-6
000302-17-0
000056-75-7
Agent
Group
Ultraviolet radiation (wavelengths 100-400 nm,
encompassing UVA, UVB, and UVC)
Ultraviolet-emitting tanning devices
Vinyl chloride
Wood dust
X- and Gamma-Radiation
Acrylamide
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Adriamycin
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Androgenic (anabolic) steroids
Art glass, glass containers and pressed ware
(manufacture of)
Azacitidine
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Biomass fuel (primarily wood), indoor emissions from
household combustion of
Bischloroethyl nitrosourea (BCNU)
Bitumens, occupational exposure to oxidized bitumens
and their emissions during roofing
Captafol
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Carbon electrode manufacture
Chloral
Chloral hydrate
Chloramphenicol
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
alpha-Chlorinated toluenes (benzal chloride,
benzotrichloride, benzyl chloride) and benzoyl chloride
(combined exposures)
000098-87-3
000098-07-7
000100-44-7
000098-88-4
013010-47-4 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000095-69-2 4-Chloro-ortho-toluidine
6
1
Volume
Year1
100D
2012
1
1
1
1
2A
100D
97, 100F
62, 100C
75, 100D
60
2012
2012
2012
2012
1994
2A
10, Sup 7
1987
2A
2A
Sup 7
58
1987
1993
2A
50
1990
2A
95
2010
2A
2A
26, Sup 7
103
1987
2013
2A
53
1991
2A
2A
2A
2A
92
63, 106
84, 106
50
2010
2014
2014
1990
2A
29, Sup 7, 71
1999
2A
26, Sup 7
1987
2A
77, 99
2010
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
Group
054749-90-5 Chlorozotocin
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
015663-27-1 Cisplatin
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
007440-48-4 Cobalt metal with tungsten carbide
012070-12-1
008001-58-9 Creosotes
027208-37-3 Cyclopenta[cd]pyrene
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
333-41-5 Diazinon
(NB: Overall evaluation upgraded to Group 2A based on
mechanistic evidence)
000224-42-0 Dibenz[a,j]acridine
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000053-70-3 Dibenz[a,h]anthracene
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000191-30-0 Dibenzo[a,l]pyrene
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000075-09-2 Dichloromethane (Methylene chloride)
000064-67-5 Diethyl sulfate
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000079-44-7 Dimethylcarbamoyl chloride
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000068-12-2 Dimethylformamide
000540-73-8 1,2-Dimethylhydrazine
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000077-78-1 Dimethyl sulfate
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000106-89-8 Epichlorohydrin
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000051-79-6 Ethyl carbamate (Urethane)
7
Volume
Year1
2A
50
1990
2A
26, Sup 7
1987
2A
86
2006
2A
2A
92
92
2010
2010
2A
112
Online
2015
2A
32, Sup 7,
103
2013
2A
92
2010
2A
92
2010
2A
71, 110
2A
54, 71
In
prep.
1999
2A
12, Sup 7, 71
1999
2A
47, 71, 115
2A
4, Sup 7, 71
In
prep.
1999
2A
4, Sup 7, 71
1999
2A
11, Sup 7, 71
1999
2A
7, Sup 7, 96
2010
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
Group
000106-93-4 Ethylene dibromide
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000759-73-9 N-Ethyl-N-nitrosourea
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Frying, emissions from high-temperature
000556-52-5 Glycidol
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
001071-83-6 Glyphosate
Volume
Year1
2A
15, Sup 7, 71
1999
2A
17, Sup 7
1987
2A
2A
95
77
2010
2000
2A
112
Hairdresser or barber (occupational exposure as a)
Human papillomavirus type 68
000302-01-2 Hydrazine
2A
2A
2A
022398-80-7 Indium phosphide
(NB: Overall evaluation upgraded to Group 2A)
076180-96-6 IQ (2-Amino-3-methylimidazo[4,5-f]quinoline)
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Lead compounds, inorganic
Malaria (caused by infection with Plasmodium falciparum
in holoendemic areas)
000121-75-5 Malathion
2A
57, 99
100B
4, Sup 7, 71,
115
86
Online
2015
2010
2012
In
prep.
2006
2A
56
1993
2A
2A
87
104
2006
2013
2A
30, Sup 7,
112
2A
115
2A
2A
104
40, Sup 7
In
prep.
2013
1987
2A
7, Sup 7, 71
1999
2A
4, Sup 7
1987
2A
17, Sup 7
1987
Mate, hot (see Very hot beverages)
000149-30-4 2-Mercaptobenzothiazole
000484-20-8
000066-27-3
000070-25-7
000684-93-5
Merkel cell polyomavirus (MCV)
5-Methoxypsoralen
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Methyl methanesulfonate
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
N-Methyl-N´-nitro-N-nitrosoguanidine (MNNG)
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
N-Methyl-N-nitrosourea
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
8
Online
2015
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
Group
Year1
2A
94
2010
2A
2A
2A
2A
46, 105
9, Sup 7
46, 105
17, Sup 7
2013
1987
2013
1987
2A
17, Sup 7
1987
2A
101
2013
2A
53
1991
2A
2A
45
108
1989
2016
059536-65-1 Polybrominated biphenyls
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data, namely
mechanistic similarity with polychlorinated biphenyls
classified in Group 1)
2A
41, Sup 7,
107
2016
000366-70-1 Procarbazine hydrochloride
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
2A
26, Sup 7
1987
001120-71-4 1,3-Propane sultone
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Red meat (consumption of)
2A
4, Sup 7, 71,
110
In
prep.
2A
114
Shiftwork that involves circadian disruption
000409-21-2 Silicon carbide whiskers
2A
2A
98
111
000096-09-3 Styrene-7,8-oxide
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
029767-20-2 Teniposide
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000079-94-7 Tetrabromobisphenol A
2A
60
In
prep.
2010
In
prep.
1994
2A
76
2000
2A
115
In
prep.
007496-02-8
000051-75-2
005522-43-0
000055-18-5
000062-75-9
000088-72-2
111025-46-8
Nitrate or nitrite (ingested) under conditions that result in
endogenous nitrosation
6-Nitrochrysene
Nitrogen mustard
1-Nitropyrene
N-Nitrosodiethylamine
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
N-Nitrosodimethylamine
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
2-Nitrotoluene
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Non-arsenical insecticides (occupational exposures in
spraying and application of)
Petroleum refining (occupational exposures in)
Pioglitazone
Volume
9
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
Group
000127-18-4 Tetrachloroethylene (Perchloroethylene)
000116-14-3 Tetrafluoroethylene
(NB: Overall evaluation upgraded to Group 2A)
000096-18-4 1,2,3-Trichloropropane
000126-72-7 Tris(2,3-dibromopropyl) phosphate
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Very hot beverages at above 65 °C (drinking)
2A
2A
000593-60-2 Vinyl bromide
(NB: (1) Overall evaluation upgraded to Group 2A
based on mechanistic and other relevant data;
(2) For practical purposes, vinyl bromide should be
considered to act similarly to the human carcinogen
vinyl chloride.)
000075-02-5 Vinyl fluoride
(NB: (1) Overall evaluation upgraded to Group 2A
based on mechanistic and other relevant data;
(2) For practical purposes, vinyl fluoride should be
considered to act similarly to the human carcinogen
vinyl chloride.)
026148-68-5 A-alpha-C (2-Amino-9H-pyrido[2,3-b]indole)
000075-07-0 Acetaldehyde
000060-35-5 Acetamide
000107-13-1 Acrylonitrile
003688-53-7 AF-2 [2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide]
006795-23-9 Aflatoxin M1
Aloe vera, whole leaf extract
000060-09-3 para-Aminoazobenzene
000097-56-3 ortho-Aminoazotoluene
000081-49-2 1-Amino-2,4-dibromoanthraquinone
000712-68-5 2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole
051264-14-3 Amsacrine
000090-04-0 ortho-Anisidine
000084-65-1 Anthraquinone
001309-64-4 Antimony trioxide
000140-57-8 Aramite®
000492-80-8 Auramine
000115-02-6 Azaserine
2B
10
Volume
Year1
2A
2A
63, 106
19, Sup 7,
71, 110
63
20, Sup 7, 71
2014
In
prep.
1995
1999
2A
116
2A
39, Sup 7,
71, 97
In
prep.
2008
2A
63, 97
2008
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
40, Sup 7
36, Sup 7, 71
7, Sup 7, 71
71
31, Sup 7
56
108
8, Sup 7
8, Sup 7
101
7, Sup 7
76
73
101
47
5, Sup 7
1, Sup 7, 99,
100F
10, Sup 7
1987
1999
1999
1999
1987
1993
2016
1987
1987
2013
1987
2000
1999
2013
1989
1987
2012
1987
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
Group
000151-56-4 Aziridine
(NB: Overall evaluation upgraded to Group 2B with
supporting evidence from other relevant data)
000202-33-5 Benz[j]aceanthrylene
(NB: Overall evaluation upgraded to Group 2B with
supporting mechanistic and other relevant data)
000056-55-3 Benz[a]anthracene
000205-99-2 Benzo[b]fluoranthene
000205-82-3 Benzo[j]fluoranthene
000207-08-9 Benzo[k]fluoranthene
000271-89-6 Benzofuran
000195-19-7 Benzo[c]phenanthrene
(NB: Overall evaluation upgraded to Group 2B with
supporting evidence from other relevant data)
000119-61-9 Benzophenone
001694-09-3 Benzyl violet 4B
003296-90-0 2,2-Bis(bromomethyl)propane-1,3-diol
Bitumens, occupational exposure to hard bitumens and
their emissions during mastic asphalt work
008052-42-4 Bitumens, occupational exposure to straight-run bitumens
064741-56-6 and their emissions during road paving
BK polyomavirus (BKV)
011056-06-7 Bleomycins
(NB: Overall evaluation upgraded to Group 2B with
supporting evidence from other relevant data)
Bracken fern
005589-96-8 Bromochloroacetic acid
000075-27-4 Bromodichloromethane
000106-94-5 1-Bromopropane
025013-16-5
003068-88-0
000331-39-5
000086-74-8
Butylated hydroxyanisole (BHA)
beta-Butyrolactone
Caffeic acid
Carbazole
Volume
2B
9, Sup 7, 71
1999
2B
92
2010
2B
2B
2B
2B
2B
2B
92
92
92
92
63
92
2010
2010
2010
2010
1995
2010
2B
2B
2B
2B
101
16, Sup 7
77
103
2013
1987
2000
2013
2B
103
2013
2B
2B
104
26, Sup 7
2013
1987
2B
2B
2B
2B
40, Sup 7
101
52, 71
115
2B
2B
2B
2B
1987
2013
1999
In
prep.
1987
1999
1993
2013
001333-86-4 Carbon black
308068-56-6 Carbon nanotubes, multi-walled MWCNT-7
2B
2B
40, Sup 7
11, Sup 7, 71
56
32, Sup 7,
71, 103
65, 93
111
000056-23-5 Carbon tetrachloride
Carpentry and joinery
053973-98-1 Carrageenan, degraded (Poligeenan)
2B
2B
2B
20, Sup 7, 71
25, Sup 7
31, Sup 7
11
Year1
2010
In
prep.
1999
1987
1987
Agents Classified by the IARC Monographs, Volumes 1–116
Agent
000120-80-9
000057-74-9
000143-50-0
000115-28-6
Catechol
Chlordane
Chlordecone (Kepone)
Chlorendic acid
Chlorinated paraffins of average carbon chain length C12
and average degree of chlorination approximately 60%
para-Chloroaniline
3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone
Chloroform
1-Chloro-2-methylpropene
3-Chloro-2-methylpropene, technical grade
2B
2B
2B
2B
2B
15, Sup 7, 71
79
20, Sup 7
48
48
1999
2001
1987
1990
1990
2B
2B
2B
2B
2B
57
84
73
63
63, 115
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
41, Sup 7
27, Sup 7
71
73
92
57
57, 99
57
8, Sup 7
52
007440-48-4
010026-24-1
068603-42-9
000120-71-8
000098-82-8
014901-08-7
004342-03-4
000117-10-2
020830-81-3
000050-29-3
Chlorophenoxy herbicides
4-Chloro-ortho-phenylenediamine
Chloroprene
Chlorothalonil
Chrysene
CI Acid Red 114
CI Basic Red 9
CI Direct Blue 15
Citrus Red No. 2
Cobalt and cobalt compounds
(NB: Evaluated as a group)
Cobalt metal without tungsten carbide
Cobalt sulfate and other soluble cobalt(II) salts
Coconut oil diethanolamine condensate
para-Cresidine
Cumene
Cycasin
Dacarbazine
Dantron (Chrysazin; 1,8-Dihydroxyanthraquinone)
Daunomycin
DDT (4,4'-Dichlorodiphenyltrichloroethane)
1993
2004
1999
1995
In
prep.
1987
1987
1999
1999
2010
1993
2010
1993
1987
1991
2B
2B
2B
2B
2B
2B
2B
2B
2B
2A
000613-35-4
000615-05-4
000101-80-4
000095-80-7
N,N'-Diacetylbenzidine
2,4-Diaminoanisole
4,4'-Diaminodiphenyl ether
2,4-Diaminotoluene
2B
2B
2B
2B
86
86
101
27, Sup 7
101
10, Sup 7
26, Sup 7
50
10, Sup 7
Sup 7, 53,
113
16, Sup 7
79
29, Sup 7
16, Sup 7
2006
2006
2013
1987
2013
1987
1987
1990
1987
Online
2016
1987
2001
1987
1987
000106-47-8
077439-76-0
000067-66-3
000513-37-1
000563-47-3
000095-83-0
000126-99-8
001897-45-6
000218-01-9
006459-94-5
000569-61-9
002429-74-5
006358-53-8
007440-48-4
Group
12
Volume
Year1
CAS No
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
Group
000226-36-8 Dibenz[a,h]acridine
2B
000224-53-3 Dibenz[c,h]acridine
(NB: Overall evaluation upgraded to Group 2B with
supporting evidence from other relevant data)
000194-59-2 7H-Dibenzo[c,g]carbazole
2B
2B
000189-64-0
000189-55-9
000631-64-1
003252-43-5
000096-12-8
000096-13-9
000079-43-6
000106-46-7
000091-94-1
028434-86-8
000107-06-2
000094-75-7
000096-23-1
000542-75-6
000062-73-7
000111-42-2
000117-81-7
001615-80-1
000101-90-6
020830-75-5
000094-58-6
002973-10-6
000119-90-4
000060-11-7
025962-77-0
000087-62-7
000075-60-5
000119-93-7
Dibenzo[a,h]pyrene
Dibenzo[a,i]pyrene
Dibromoacetic acid
Dibromoacetonitrile
1,2-Dibromo-3-chloropropane
2,3-Dibromopropan-1-ol
Dichloroacetic acid
para-Dichlorobenzene
3,3'-Dichlorobenzidine
3,3'-Dichloro-4,4'-diaminodiphenyl ether
1,2-Dichloroethane
2,4-D (2,4-dichlorophenoxyacetic acid) (see also
Chlorophenoxy herbicides)
1,3-Dichloro-2-propanol
1,3-Dichloropropene (technical-grade)
Dichlorvos
Diesel fuel, marine
(NB: Overall evaluation upgraded to Group 2B with
supporting evidence from other relevant data)
Diethanolamine
Di(2-ethylhexyl)phthalate
1,2-Diethylhydrazine
Diglycidyl resorcinol ether
Digoxin
Dihydrosafrole
Diisopropyl sulfate
3,3'-Dimethoxybenzidine (ortho-Dianisidine)
para-Dimethylaminoazobenzene
trans-2-[(Dimethylamino)methylimino]-5-[2-(5-nitro-2furyl)-vinyl]-1,3,4-oxadiazole
2,6-Dimethylaniline (2,6-Xylidine)
Dimethylarsinic acid
3,3'-Dimethylbenzidine (ortho-Tolidine)
13
Volume
Year1
32, Sup 7,
103
103
2013
2013
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
32, Sup 7,
103
92
92
101
52, 71, 101
20, Sup 7, 71
77
84, 106
73
29, Sup 7
16, Sup 7
20, Sup 7, 71
113
2B
2B
2B
2B
101
41, Sup 7, 71
53
45
2010
2010
2013
2013
1999
2000
2014
1999
1987
1987
1999
In
prep.
2013
1999
1991
1989
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
77, 101
77, 101
4, Sup 7, 71
36, Sup 7, 71
108
10, Sup 7
54, 71
4, Sup 7
8, Sup 7
7, Sup 7
2013
2013
1999
1999
2016
1987
1999
1987
1987
1987
2B
2B
2B
57
100C
1, Sup 7
1993
2012
1987
2013
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
Group
Volume
Year1
000057-14-7 1,1-Dimethylhydrazine
000099-97-8 Dimethyl-p-toluidine
2B
2B
4, Sup 7, 71
115
105735-71-5
022506-53-2
075321-20-9
042397-64-8
042397-65-9
000121-14-2
000606-20-2
000123-91-1
002475-45-8
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
46, 65, 105
46, 65, 105
46, 105
46, 105
46, 105
65
65
11, Sup 7, 71
48
63
46, 105
47, 71
1999
In
prep.
2013
2013
2013
2013
2013
1996
1996
1999
1990
1995
2013
1999
2B
2B
2B
2B
2B
2B
2B
2B
2B
39, Sup 7, 71
77
7, Sup 7
98
7, Sup 7
45
82
63
56
1999
2000
1987
2010
1987
1989
2002
1995
1993
2B
45
1989
2B
2B
108
40, Sup 7
2016
1987
2B
2B
2B
2B
2B
2B
2B
40, Sup 7
11, Sup 7, 71
108
79
57
79
79
1987
1999
2016
2001
1993
2001
2001
000106-88-7
000140-88-5
000100-41-4
000062-50-0
003570-75-0
116355-83-0
000110-00-9
116355-83-0
090045-36-6
067730-11-4
067730-10-3
000765-34-4
000126-07-8
002784-94-3
000076-44-8
000118-74-1
3,7-Dinitrofluoranthene
3,9-Dinitrofluoranthene
1,3-Dinitropyrene
1,6-Dinitropyrene
1,8-Dinitropyrene
2,4-Dinitrotoluene
2,6-Dinitrotoluene
1,4-Dioxane
Disperse Blue 1
Dry cleaning (occupational exposures in)
Engine exhaust, gasoline
1,2-Epoxybutane
(NB: Overall evaluation upgraded to Group 2B with
supporting evidence from other relevant data)
Ethyl acrylate
Ethylbenzene
Ethyl methanesulfonate
Firefighter (occupational exposure as a)
2-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazole
Fuel oils, residual (heavy)
Fumonisin B1
Furan
Fusarium moniliforme, toxins derived from (fumonisin B1,
fumonisin B2, and fusarin C)
Gasoline
(NB: Overall evaluation upgraded to Group 2B with
supporting evidence from other relevant data)
Ginkgo biloba extract
Glu-P-1 (2-Amino-6-methyldipyrido[1,2-a:3',2'd]imidazole)
Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole)
Glycidaldehyde
Goldenseal root powder
Griseofulvin
HC Blue No. 1
Heptachlor
Hexachlorobenzene
14
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
Group
Volume
Year1
Hexachlorocyclohexanes (see also Lindane)
000067-72-1 Hexachloroethane
000142-83-6 2,4-Hexadienal
000680-31-9 Hexamethylphosphoramide
Human immunodeficiency virus type 2 (infection with)
Human papillomavirus types 5 and 8 (in patients with
epidermodysplasia verruciformis)
Human papillomavirus types 26, 53, 66, 67, 70, 73, 82
Human papillomavirus types 30, 34, 69, 85, 97
(NB: Classified by phylogenetic analogy to the HPV
genus alpha types classified in Group 1)
2B
2B
2B
2B
2B
2B
20, Sup 7
73
101
15, Sup 7, 71
67
100B
1987
1999
2013
1999
1996
2012
2B
2B
100B
100B
2012
2012
000058-93-5 Hydrochlorothiazide
000129-43-1 1-Hydroxyanthraquinone
Implanted foreign bodies of metallic cobalt, metallic
nickel, and an alloy powder containing 66–67% nickel,
13–16% chromium and 7% iron
000193-39-5 Indeno[1,2,3-cd]pyrene
009004-66-4 Iron-dextran complex
000078-79-5 Isoprene
JC polyomavirus (JCV)
009000-38-8 Kava extract
000303-34-4 Lasiocarpine
007439-92-1 Lead
2B
2B
2B
50, 108
82
74
2016
2002
1999
2B
2B
2B
2B
2B
2B
2B
92
2, Sup 7
60, 71
104
108
10, Sup 7
23, Sup 7
2010
1987
1999
2013
2016
1987
1987
2B
2B
2B
57, 99, 100F
80
40, Sup 7
2012
2002
1987
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
21, Sup 7
56
56
9, Sup 7
74
100C
9, Sup 7, 71
10, Sup 7
92
4, Sup 7
1987
1993
1993
1987
1999
2012
1999
1987
2010
1987
000632-99-5 Magenta
Magnetic fields, extremely low-frequency
068006-83-7 MeA-alpha-C (2-Amino-3-methyl-9H-pyrido[2,3-b]indole)
Meat, red (see Red meat)
000071-58-9 Medroxyprogesterone acetate
077094-11-2 MeIQ (2-Amino-3,4-dimethylimidazo[4,5-f]quinoline)
077500-04-0 MeIQx (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline)
000531-76-0 Merphalan
Metallic implants prepared as thin smooth films
000124-58-3 Methylarsonic acid
000075-55-8 2-Methylaziridine (Propyleneimine)
000592-62-1 Methylazoxymethanol acetate
003697-24-3 5-Methylchrysene
000838-88-0 4,4'-Methylene bis(2-methylaniline)
15
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
Group
000101-77-9
000093-15-2
000693-98-1
000822-36-6
000108-10-1
4,4'-Methylenedianiline
Methyleugenol
2-Methylimidazole
4-Methylimidazole
Methyl isobutyl ketone
Methylmercury compounds
(NB: Evaluated as a group)
000129-15-7 2-Methyl-1-nitroanthraquinone (uncertain purity)
000615-53-2 N-Methyl-N-nitrosourethane
000098-83-9 -Methylstyrene
Volume
Year1
2B
2B
2B
2B
2B
2B
39, Sup 7
101
101
101
101
58
1987
2013
2013
2013
2013
1993
2B
2B
2B
27, Sup 7
4, Sup 7
101
1987
1987
2013
000056-04-2 Methylthiouracil
000443-48-1 Metronidazole
000101-61-1 Michler’s base [4,4-methylenebis(N,N-dimethyl)benzenamine]
000090-94-8 Michler’s ketone [4,4-Bis(dimethylamino)benzophenone]
2B
2B
2B
79
13, Sup 7
27, Sup 7, 99
2001
1987
2010
2B
99
2010
101043-37-2
002385-85-5
000050-07-7
065271-80-9
000096-24-2
000315-22-0
003795-88-8
2B
2B
2B
2B
2B
2B
2B
94
20, Sup 7
10, Sup 7
76
101
10, Sup 7
7, Sup 7
2010
1987
1987
2000
2013
1987
1987
2B
2B
2B
2B
2B
24, Sup 7
82
49
13, Sup 7
73
1987
2002
1990
1987
1999
2B
2B
2B
16, Sup 7
65
105
1987
1996
2013
2B
2B
2B
65
30, Sup 7
46, 105
1996
1987
2013
308068-56-6
003771-19-5
000091-20-3
007440-02-0
000061-57-4
000139-13-9
000602-87-9
000091-23-6
017117-34-9
000098-95-3
001836-75-5
000607-57-8
Microcystin-LR
Mirex
Mitomycin C
Mitoxantrone
3-Monochloro-1,2-propanediol
Monocrotaline
5-(Morpholinomethyl)-3-[(5-nitrofurfurylidene)amino]-2oxazolidinone
Multi-walled carbon nanotubes MWCNT-7 (see Carbon
nanotubes, multi-walled MWCNT-7)
Nafenopin
Naphthalene
Nickel, metallic and alloys
Niridazole
Nitrilotriacetic acid and its salts
(NB: Evaluated as a group)
5-Nitroacenaphthene
2-Nitroanisole
3-Nitrobenzanthrone
(NB: Overall evaluation upgraded to Group 2B with
supporting evidence from other relevant data)
Nitrobenzene
Nitrofen (technical-grade)
2-Nitrofluorene
16
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
000555-84-0
000531-82-8
000126-85-2
000075-52-5
000079-46-9
057835-92-4
000924-16-3
001116-54-7
000621-64-7
060153-49-3
010595-95-6
004549-40-0
000059-89-2
000100-75-4
000930-55-2
013256-22-9
000303-47-9
002646-17-5
000604-75-1
012174-11-7
000794-93-4
000056-38-2
1-[(5-Nitrofurfurylidene)amino]-2-imidazolidinone
N-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide
Nitrogen mustard N-oxide
Nitromethane
2-Nitropropane
4-Nitropyrene
N-Nitrosodi-n-butylamine
N-Nitrosodiethanolamine
N-Nitrosodi-n-propylamine
3-(N-Nitrosomethylamino)propionitrile
N-Nitrosomethylethylamine
N-Nitrosomethylvinylamine
N-Nitrosomorpholine
N-Nitrosopiperidine
N-Nitrosopyrrolidine
N-Nitrososarcosine
Ochratoxin A
Oil Orange SS
Oxazepam
Palygorskite (Attapulgite) (long fibres, > 5 micrometres)
Panfuran S (containing dihydroxymethylfuratrizine)
Parathion
037319-17-8 Pentosan polysulfate sodium
000335-67-1 Perfluorooctanoic acid (PFOA)
000136-40-3
000050-06-6
000077-09-8
000063-92-3
000122-60-1
000057-41-0
105650-23-5
003564-09-8
Volume
Year1
2B
2B
7, Sup 7
7, Sup 7
9, Sup 7
77
29, Sup 7, 71
46, 105
17, Sup 7
17, Sup 7, 77
17, Sup 7
85
17, Sup 7
17, Sup 7
17, Sup 7
17, Sup 7
17, Sup 7
17, Sup 7
56
8, Sup 7
66
68
24, Sup 7
30, Sup 7,
112
108
110
2B
2B
2B
2B
2B
2B
2B
2B
2B
56
24, Sup 7
79
76
24, Sup 7
47, 71
66
56
53, 71
1987
1987
1987
2000
1999
2013
1987
2000
1987
2004
1987
1987
1987
1987
1987
1987
1993
1987
1996
1997
1987
In
prep.
2016
Online
2016
1993
1987
2001
2000
1987
1999
1996
1993
1999
2B
74
1999
2B
8, Sup 7
1987
Group
Pickled vegetables (traditional Asian)
Phenazopyridine hydrochloride
Phenobarbital
Phenolphthalein
Phenoxybenzamine hydrochloride
Phenyl glycidyl ether
Phenytoin
PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine)
Polychlorophenols and their sodium salts (mixed
exposures)
Polymeric implants prepared as thin smooth films (with
the exception of poly(glycolic acid))
Ponceau 3R
17
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
Group
Volume
Year1
003761-53-3 Ponceau MX
007758-01-2 Potassium bromate
000125-33-7 Primidone
Printing processes (occupational exposures in)
Progestins
Progestogen-only contraceptives
000057-57-8 beta-Propiolactone
000075-56-9 Propylene oxide
000051-52-5 Propylthiouracil
000089-82-7 Pulegone
Radiofrequency electromagnetic fields1
Refractory ceramic fibres
023246-96-0 Riddelliine
000094-59-7 Safrole
Schistosoma japonicum (infection with)
308076-74-6 Silicon carbide, fibrous
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
8, Sup 7
73
108
65
Sup 7
72
4, Sup 7, 71
60
79
108
102
43, 81
10, Sup 7, 82
10, Sup 7
61
111
000132-27-4 Sodium ortho-phenylphenate
Special-purpose fibres such as E-glass and '475' glass
fibres
010048-13-2 Sterigmatocystin
018883-66-4 Streptozotocin
000100-42-5 Styrene
000095-06-7 Sulfallate
000599-79-1 Sulfasalazine
Surgical implants (see Implanted foreign bodies, Metallic
implants, Polymeric implants)
014807-96-6 Talc-based body powder (perineal use of)
000630-20-6 1,1,1,2-Tetrachloroethane
2B
2B
73
81
1987
1999
2016
1996
1987
1999
1999
1994
2001
2016
2013
2002
2002
1987
1994
In
prep.
1999
2002
2B
2B
2B
2B
2B
10, Sup 7
17, Sup 7
60, 82
30, Sup 7
108
1987
1987
2002
1987
2016
2B
2B
2010
2014
000079-34-5 1,1,2,2-Tetrachloroethane
2B
000509-14-8 Tetranitromethane
022248-79-9 Tetrachlorvinphos
2B
2B
Textile manufacturing industry (work in)
000062-55-5 Thioacetamide
000139-65-1 4,4'-Thiodianiline
2B
2B
2B
93
41, Sup 7,
71, 106
20, Sup 7,
71, 106
65
30, Sup 7,
112
48
7, Sup 7
27, Sup 7
1
Includes radiofrequency electromagnetic fields from wireless phones
18
2014
1996
In
prep.
1990
1987
1987
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
000141-90-2
013463-67-7
026471-62-5
008001-35-2
000396-01-0
000817-09-4
000076-03-9
062450-06-0
062450-07-1
000072-57-1
000066-75-1
001314-62-1
000108-05-4
000100-40-3
000106-87-6
Thiouracil
Titanium dioxide
Toluene diisocyanates
Toxaphene (Polychlorinated camphenes)
Triamterene
Trichlormethine (Trimustine hydrochloride)
Trichloroacetic acid
Trp-P-1 (3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole)
Trp-P-2 (3-Amino-1-methyl-5H-pyrido[4,3-b]indole)
Trypan blue
Uracil mustard
Vanadium pentoxide
Vinyl acetate
4-Vinylcyclohexene
4-Vinylcyclohexene diepoxide
Welding fumes
(NB: Volume 100D concluded that there is sufficient
evidence for ocular melanoma in welders)
Zalcitabine
Zidovudine (AZT)
Acenaphthene
Acepyrene (3,4-dihydrocyclopenta[cd]pyrene)
Aciclovir
Acridine orange
Acriflavinium chloride
Acrolein
Acrylic acid
Acrylic fibres
Acrylonitrile-butadiene-styrene copolymers
Actinomycin D
Agaritine
Aldicarb
Aldrin
Allyl chloride
Allyl isothiocyanate
Allyl isovalerate
Amaranth
5-Aminoacenaphthene
2-Aminoanthraquinone
007481-89-2
030516-87-1
000083-32-9
025732-74-5
059277-89-3
000494-38-2
008018-07-3
000107-02-8
000079-10-7
000050-76-0
002757-90-6
000116-06-3
000309-00-2
000107-05-1
000057-06-7
002835-39-4
000915-67-3
004657-93-6
000117-79-3
Group
19
Volume
Year1
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
79
47, 93
39, Sup 7, 71
79
108
50
84, 106
31, Sup 7
31, Sup 7
8, Sup 7
9, Sup 7
86
63
60
60
49
2001
2010
1999
2001
2016
1990
2014
1987
1987
1987
1987
2006
1995
1994
1994
1990
2B
2B
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
76
76
92
92
76
16, Sup 7
13, Sup 7
63
19, Sup 7, 71
19, Sup 7
19, Sup 7
10, Sup 7
31, Sup 7
53
5, Sup 7
36, Sup 7, 71
73
36, Sup 7, 71
8, Sup 7
16, Sup 7
27, Sup 7
2000
2000
2010
2010
2000
1987
1987
1995
1999
1987
1987
1987
1987
1991
1987
1999
1999
1999
1987
1987
1987
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
000150-13-0
000082-28-0
000099-57-0
000121-88-0
000119-34-6
000121-66-4
002432-99-7
000061-82-5
para-Aminobenzoic acid
1-Amino-2-methylanthraquinone
2-Amino-4-nitrophenol
2-Amino-5-nitrophenol
4-Amino-2-nitrophenol
2-Amino-5-nitrothiazole
11-Aminoundecanoic acid
Amitrole
(NB: Overall evaluation downgraded to Group 3 with
supporting evidence from other relevant data)
Ampicillin
Anaesthetics, volatile
Angelicin plus ultraviolet A radiation
Aniline
para-Anisidine
Anthanthrene
Anthracene
Anthranilic acid
Antimony trisulfide
Apholate
para-Aramid fibrils
Arsenobetaine and other organic arsenic compounds that
are not metabolized in humans
Atrazine
(NB: Overall evaluation downgraded to Group 3 with
supporting evidence from other relevant data)
Aurothioglucose
2-(1-Aziridinyl)ethanol
Aziridyl benzoquinone
Azobenzene
11H-Benz[bc]aceanthrylene
Benz[l]aceanthrylene
Benz[a]acridine
000069-53-4
000523-50-2
000062-53-3
000104-94-9
000191-26-4
000120-12-7
000118-92-3
001345-04-6
000052-46-0
024938-64-5
064436-13-1
001912-24-9
012192-57-3
001072-52-2
000800-24-8
000103-33-3
000202-94-8
000211-91-6
000225-11-6
Group
16, Sup 7
27, Sup 7
57
57
16, Sup 7
31, Sup 7
39, Sup 7
79
1987
1987
1993
1993
1987
1987
1987
2001
3
3
3
3
3
3
3
3
3
3
3
3
50
11, Sup 7
40, Sup 7
27, Sup 7
27, Sup 7
92
92
16, Sup 7
47
9, Sup 7
68
100C
1990
1987
1987
1987
1987
2010
2010
1987
1989
1987
1997
2012
3
73
1999
3
3
3
3
3
3
3
13, Sup 7
9, Sup 7
9, Sup 7
8, Sup 7
92
92
32, Sup 7,
103
32, Sup 7,
103
92
92
92
92
1987
1987
1987
1987
2010
2010
2013
3
000214-17-5
000196-78-1
000203-33-8
000203-12-3
3
3
3
3
20
Year1
3
3
3
3
3
3
3
3
000225-51-4 Benz[c]acridine
Benzo[b]chrysene
Benzo[g]chrysene
Benzo[a]fluoranthene
Benzo[ghi]fluoranthene
Volume
2013
2010
2010
2010
2010
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
Group
000238-84-6
000243-17-4
000205-12-9
000239-35-0
000191-24-2
000192-97-2
000105-11-3
000094-36-0
000140-11-4
002168-68-5
000111-44-4
013483-18-6
056894-91-8
000108-60-1
002386-90-5
001675-54-3
Benzo[a]fluorene
Benzo[b]fluorene
Benzo[c]fluorene
Benzo[b]naphtho[2,1-d]thiophene
Benzo[ghi]perylene
Benzo[e]pyrene
para-Benzoquinone dioxime
Benzoyl peroxide
Benzyl acetate
Bis(1-aziridinyl)morpholinophosphine sulfide
Bis(2-chloroethyl)ether
1,2-Bis(chloromethoxy)ethane
1,4-Bis(chloromethoxymethyl)benzene
Bis(2-chloro-1-methylethyl)ether
Bis(2,3-epoxycyclopentyl)ether
Bisphenol A diglycidyl ether (Araldite )
Bisulfites
Blue VRS
Brilliant Blue FCF, disodium salt
Bromochloroacetonitrile
Bromoethane
Bromoform
2-Butoxyethanol
1-tert-Butoxypropan-2-ol
n-Butyl acrylate
Butylated hydroxytoluene (BHT)
Butyl benzyl phthalate
gamma-Butyrolactone
Caffeine
Calcium carbide production
Cantharidin
Captan
Carbaryl
3-Carbethoxypsoralen
Carbon nanotubes, multi-walled, other than MWCNT-7
Volume
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
92
92
92
103
92
92
29, Sup 7, 71
36, Sup 7, 71
40, Sup 7, 71
9, Sup 7
9, Sup 7, 71
15; Sup 7, 71
15; Sup 7, 71
41, Sup 7, 71
47, 71
47, 71
54
16, Sup 7
16, Sup 7
52, 71
52, 71
52, 71
88
88
39, Sup 7, 71
40, Sup 7
73
11, Sup 7, 71
51
92
10, Sup 7
30, Sup 7
12, Sup 7
40, Sup 7
111
308068-56-6 Carbon nanotubes, single-walled
3
111
003567-69-9 Carmoisine
3
8, Sup 7
000129-17-9
003844-45-9
083463-62-1
000074-96-4
000075-25-2
000111-76-2
057018-52-7
000141-32-2
000128-37-0
000085-68-7
000096-48-0
000058-08-2
000056-25-7
000133-06-2
000063-25-2
020073-24-9
308068-56-6
21
Year1
2010
2010
2010
2013
2010
2010
1999
1999
1999
1987
1999
1999
1999
1999
1999
1999
1992
1987
1987
1999
1999
1999
2006
2006
1999
1987
1999
1999
1991
2010
1987
1987
1987
1987
In
prep.
In
prep.
1987
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
Group
009000-07-1 Carrageenan, native
Ceramic implants
010599-90-3 Chloramine
006164-98-3 Chlordimeform
Chlorinated drinking-water
000107-14-2 Chloroacetonitrile
000510-15-6 Chlorobenzilate
000124-48-1 Chlorodibromomethane
000075-45-6 Chlorodifluoromethane
000075-00-3 Chloroethane
000593-70-4 Chlorofluoromethane
000088-73-3
000121-73-3
000100-00-5
005131-60-2
000101-21-3
000054-05-7
000095-79-4
000075-88-7
000057-88-5
007440-47-3
016065-83-1
000532-82-1
006373-74-6
000523-44-4
001936-15-8
002425-85-6
051481-61-9
000087-29-6
000518-75-2
000637-07-0
000050-41-9
Volume
Year1
3
3
3
3
3
3
3
3
3
3
3
31, Sup 7
74
84
30, Sup 7
52
52, 71
30, Sup 7
52, 71
41, Sup 7, 71
52, 71
41, Sup 7, 71
1987
1999
2004
1987
1991
1999
1987
1999
1999
1999
1999
Chloronitrobenzenes
3
65
1996
4-Chloro-meta-phenylenediamine
Chloropropham
Chloroquine
5-Chloro-ortho-toluidine
2-Chloro-1,1,1-trifluoroethane
Cholesterol
Chromium, metallic
Chromium (III) compounds
Chrysoidine
CI Acid Orange 3
CI Acid Orange 20
CI Orange G
CI Pigment Red 3
Cimetidine
Cinnamyl anthranilate
Citrinin
Clofibrate
Clomiphene citrate
Coal dust
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
27, Sup 7
12, Sup 7
13, Sup 7
77, 99
41, Sup 7, 71
31, Sup 7
49
49
8, Sup 7
57
8, Sup 7
8, Sup 7
57
50
77
40, Sup 7
66
21, Sup 7
68
1987
1987
1987
2010
1999
1987
1990
1990
1987
1993
1987
1987
1993
1990
2000
1987
1996
1987
1997
22
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
010380-28-6
000191-07-1
000091-64-5
000102-50-1
004170-30-3
008002-05-9
000139-05-9
012663-46-6
000108-94-1
000202-98-2
007099-43-6
005160-02-1
000080-08-0
001163-19-5
052918-63-5
000083-63-6
002303-16-4
000099-56-9
005307-14-2
000095-70-5
000439-14-5
000334-88-3
000215-58-7
000224-41-9
000262-12-4
005385-75-1
000207-83-0
000192-47-2
000192-65-4
000192-51-8
000132-65-0
003018-12-0
Agent
Coffee (drinking)
(NB: There is evidence suggesting lack of
carcinogenicity in humans of coffee drinking for cancers
of the pancreas, liver, female breast, uterine
endometrium, and prostate. Inverse associations with
coffee drinking have been observed with cancers of the
liver and uterine endometrium.)
Copper 8-hydroxyquinoline
Coronene
Coumarin
meta-Cresidine
Crotonaldehyde
Crude oil
Cyclamates (sodium cyclamate)
Cyclochlorotine
Cyclohexanone
4H-Cyclopenta[def]chrysene
5,6-Cyclopenteno-1,2-benzanthracene
D & C Red No. 9
Dapsone
Decabromodiphenyl oxide
Deltamethrin
Dental materials
Diacetylaminoazotoluene
Diallate
1,2-Diamino-4-nitrobenzene
1,4-Diamino-2-nitrobenzene
2,5-Diaminotoluene
Diazepam
Diazomethane
Dibenz[a,c]anthracene
Dibenz[a,j]anthracene
Dibenzo-para-dioxin
Dibenzo[a,e]fluoranthene
13H-Dibenzo[a,g]fluorene
Dibenzo[h,rst]pentaphene
Dibenzo[a,e]pyrene
Dibenzo[e,l]pyrene
Dibenzothiophene
Dichloroacetonitrile
23
Year1
Group
Volume
3
51, 116
In
prep.
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
15, Sup 7
32, Sup 7
77
27, Sup 7
63
45
73
10, Sup 7
47, 71
92
92
57
24, Sup 7
48, 71
53
74
8, Sup 7
30, Sup 7
16, Sup 7
57
16, Sup 7
66
7, Sup 7
92
92
69
92
92
92
92
92
103
52, 71
1987
1987
2000
1987
1995
1989
1999
1987
1999
2010
2010
1993
1987
1999
1991
1999
1987
1987
1987
1993
1987
1996
1987
2010
2010
1997
2010
2010
2010
2010
2010
2013
1999
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
007572-29-4
000541-73-1
000095-50-1
000110-57-6
000609-20-1
000115-32-2
069655-05-6
000060-57-1
Dichloroacetylene
meta-Dichlorobenzene
ortho-Dichlorobenzene
trans-1,4-Dichlorobutene
2,6-Dichloro-para-phenylenediamine
Dicofol
Didanosine
Dieldrin
Diesel fuels, distillate (light)
Di(2-ethylhexyl) adipate
N,N'-Diethylthiourea
Dihydroaceanthrylene
Dihydroxymethylfuratrizine (see also Panfuran S)
Dimethoxane
3,3'-Dimethoxybenzidine-4,4'-diisocyanate
para-Dimethylaminoazobenzenediazo sodium sulfonate
4,4'-Dimethylangelicin plus ultraviolet A radiation
4,5'-Dimethylangelicin plus ultraviolet A radiation
N,N-Dimethylaniline
Dimethyl hydrogen phosphite
1,4-Dimethylphenanthrene
Dinitrosopentamethylenetetramine
3,5-Dinitrotoluene
2,4'-Diphenyldiamine
Disperse Yellow 3
Disulfiram
Dithranol
Doxefazepam
Doxylamine succinate
Droloxifene
Dulcin
Electric fields, extremely low-frequency
Electric fields, static
Endrin
Eosin
3,4-Epoxy-6-methylcyclohexylmethyl-3,4-epoxy-6methylcyclo-hexanecarboxylate
cis-9,10-Epoxystearic acid
000103-23-1
000105-55-5
000641-48-5
000794-93-4
000828-00-2
000091-93-0
000140-56-7
022975-76-4
004063-41-6
000121-69-7
000868-85-9
022349-59-3
000101-25-7
000618-85-9
000492-17-1
002832-40-8
000097-77-8
001143-38-0
040762-15-0
000562-10-7
082413-20-5
000150-69-6
000072-20-8
015086-94-9
000141-37-7
024560-98-3
Group
24
Volume
Year1
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
39, Sup 7, 71
73
73
15, Sup 7, 71
39, Sup 7
30, Sup 7
76
5, Sup 7
45
77
79
92
24, Sup 7
15, Sup 7
39, Sup 7
8, Sup 7
Sup 7
Sup 7
57
48, 71
92
11, Sup 7
65
16, Sup 7
48
12, Sup 7
13; Sup 7
66
79
66
12, Sup 7
80
80
5, Sup 7
15, Sup 7
11, Sup 7, 71
1999
1999
1999
1999
1987
1987
2000
1987
1989
2000
2001
2010
1987
1987
1987
1987
1987
1987
1993
1999
2010
1987
1996
1987
1990
1987
1987
1996
2001
1996
1987
2002
2002
1987
1987
1999
3
11, Sup 7, 71
1999
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
029975-16-4
000536-33-4
000074-85-1
000420-12-2
000096-45-7
Estazolam
Ethionamide
Ethylene
Ethylene sulfide
Ethylenethiourea
(NB: Overall evaluation downgraded to Group 3 with
supporting evidence from other relevant data)
2-Ethylhexyl acrylate
Ethyl selenac
Ethyl tellurac
Eugenol
Evans blue
Fast Green FCF
Fenvalerate
Ferbam
Ferric oxide
Flat-glass and specialty glass (manufacture of)
Fluometuron
Fluoranthene
Fluorene
Fluorescent lighting
Fluorides (inorganic, used in drinking-water)
5-Fluorouracil
Foreign bodies (see Ceramic implants, Dental materials,
Implanted foreign bodies, Organic polymeric materials,
Orthopaedic implants, Silicone breast implants)
Fuel oils, distillate (light)
Furazolidone
Furfural
Furosemide (Frusemide)
Fusarium graminearum, F. culmorum, and F.
crookwellense, toxins derived from (zearalenone,
deoxynivalenol, nivalenol, and fusarenone X)
Fusarium sporotrichioides, toxins derived from (T-2 toxin)
Gemfibrozil
Glass filament, continuous
Glycidyl oleate
Glycidyl stearate
Guinea Green B
Gyromitrin
000103-11-7
005456-28-0
020941-65-5
000097-53-0
000314-13-6
002353-45-9
051630-58-1
014484-64-1
001309-37-1
002164-17-2
000206-44-0
000086-73-7
016984-48-8
000051-21-8
000067-45-8
000098-01-1
000054-31-9
025812-30-0
005431-33-4
007460-84-6
004680-78-8
016568-02-8
Group
25
Volume
Year1
3
3
3
3
3
66
13, Sup 7
60
11, Sup 7
79
1996
1987
1994
1987
2001
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
60
12, Sup 7
12, Sup 7
36, Sup 7
8, Sup 7
16, Sup 7
53
12, Sup 7
1, Sup 7
58
30, Sup 7
92
92
55
27, Sup 7
26, Sup 7
1994
1987
1987
1987
1987
1987
1991
1987
1987
1993
1987
2010
2010
1992
1987
1987
3
3
3
3
3
45
31, Sup 7
63
50
56
1989
1987
1995
1990
1993
3
3
3
3
3
3
3
56
66
43, 81
11, Sup 7
11, Sup 7
16, Sup 7
31, Sup 7
1993
1996
2002
1987
1987
1987
1987
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
Group
001317-60-8 Haematite
Hair colouring products (personal use of)
033229-34-4 HC Blue No. 2
002871-01-4 HC Red No. 3
059820-43-8 HC Yellow No. 4
Hepatitis D virus
000087-68-3 Hexachlorobutadiene
000070-30-4 Hexachlorophene
Human papillomavirus genus beta (except types 5 and 8)
and genus gamma
Human papillomavirus types 6 and 11
Human T-cell lymphotropic virus type II
023255-93-8 Hycanthone mesylate
000086-54-4 Hydralazine
007647-01-0 Hydrochloric acid
007722-84-1 Hydrogen peroxide
000123-31-9 Hydroquinone
001689-82-3 4-Hydroxyazobenzene
000148-24-3 8-Hydroxyquinoline
026782-43-4 Hydroxysenkirkine
000127-07-1 Hydroxyurea
Hypochlorite salts
Implanted foreign bodies of metallic chromium or titanium
and of cobalt-based, chromium-based, and titaniumbased alloys, stainless steel, and depleted uranium
Insulation glass wool
009004-51-7 Iron-dextrin complex
001338-16-5 Iron sorbitol-citric acid complex
015503-86-3 Isatidine
000054-85-3 Isonicotinic acid hydrazide (Isoniazid)
003778-73-2 Isophosphamide
000067-63-0 Isopropyl alcohol
Isopropyl oils
000120-58-1 Isosafrole
006870-67-3 Jacobine
Jet fuel
000520-18-3 Kaempferol
000501-30-4 Kojic acid
000105-74-8 Lauroyl peroxide
26
Volume
Year1
3
3
3
3
3
3
3
3
3
1, Sup 7
57, 99
57
57
57
59
73
20, Sup 7
90, 100B
1987
2010
1993
1993
1993
1994
1999
1987
2012
3
3
3
3
3
3
3
3
3
3
3
3
3
90, 100B
67
13, Sup 7
24, Sup 7
54
36, Sup 7, 71
15, Sup 7, 71
8, Sup 7
13, Sup 7
10, Sup 7
76
52
74
2012
1996
1987
1987
1992
1999
1999
1987
1987
1987
2000
1991
1999
3
3
3
3
3
3
3
3
3
3
3
3
3
3
43, 81
2, Sup 7
2, Sup 7
10, Sup 7
4, Sup 7
26, Sup 7
15, Sup 7, 71
15, Sup 7, 71
10, Sup 7
10, Sup 7
45
31, Sup 7
79
36, Sup 7, 71
2002
1987
1987
1987
1987
1987
1999
1999
1987
1987
1989
1987
2001
1999
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
Group
Volume
Year1
3
23, Sup 7, 87
2006
3
3
3
3
25, Sup 7
25, Sup 7
16, Sup 7
73
1987
1987
1987
1999
3
3
3
3
3
3
3
3
3
25, Sup 7
10, Sup 7
82
80
4, Sup 7
36, Sup 7, 71
12, Sup 7
9, Sup 7
51, 116
013045-94-8 Medphalan
000108-78-1 Melamine
(NB: Overall evaluation downgraded to Group 3 with
supporting evidence from other relevant data)
3
3
9, Sup 7
73
1987
1987
2002
2002
1987
1999
1987
1987
In
prep.
1987
1999
000050-44-2 6-Mercaptopurine
007439-97-6 Mercury and inorganic mercury compounds
Metabisulfites
000060-56-0 Methimazole
000059-05-2 Methotrexate
000072-43-5 Methoxychlor
000096-33-3 Methyl acrylate
073459-03-7 5-Methylangelicin plus ultraviolet A radiation
000074-83-9 Methyl bromide
001634-04-4 Methyl tert-butyl ether
000598-55-0 Methyl carbamate
000074-87-3 Methyl chloride
003351-28-8 1-Methylchrysene
3
3
3
3
3
3
3
3
3
3
3
3
3
26, Sup 7
58
54
79
26, Sup 7
20, Sup 7
39, Sup 7, 71
Sup 7
41, Sup 7, 71
73
12, Sup 7
41, Sup 7, 71
92
1987
1993
1992
2001
1987
1987
1999
1987
1999
1999
1987
1999
2010
005141-20-8
005989-27-5
021884-44-6
000123-33-1
000542-78-9
012427-38-2
000551-74-6
Lead compounds, organic
(NB: Organic lead compounds are metabolized at least
in part, to ionic lead both in humans and animals. To the
extent that ionic lead, generated from organic lead, is
present in the body, it will be expected to exert the
toxicities associated with inorganic lead.)
Leather goods manufacture
Leather tanning and processing
Light Green SF
d-Limonene
(NB: Overall evaluation downgraded to Group 3 with
supporting evidence from other relevant data)
Lumber and sawmill industries (including logging)
Luteoskyrin
Madder root (Rubia tinctorum)
Magnetic fields, static
Maleic hydrazide
Malonaldehyde
Maneb
Mannomustine dihydrochloride
Mate, not very hot (drinking)
27
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
003351-32-4
003351-31-3
003351-30-2
001705-85-7
000099-80-9
007220-79-3
000101-68-8
033543-31-6
001706-01-0
000078-98-8
000074-88-4
000080-62-6
090456-67-0
000298-00-0
000832-69-9
085878-63-3
000493-52-7
000144-34-3
2-Methylchrysene
3-Methylchrysene
4-Methylchrysene
6-Methylchrysene
N-Methyl-N,4-dinitrosoaniline
Methylene blue
4,4'-Methylenediphenyl diisocyanate
2-Methylfluoranthene
3-Methylfluoranthene
Methylglyoxal
Methyl iodide
Methyl methacrylate
N-Methylolacrylamide
Methyl parathion
1-Methylphenanthrene
7-Methylpyrido[3,4-c]psoralen
Methyl red
Methyl selenac
Microcystis extracts
Mineral oils, highly-refined
Modacrylic fibres
Monuron
Morpholine
Multi-walled carbon nanotubes other than MWCNT-7
(see Carbon nanotubes, multi-walled, other than
MWCNT-7)
Musk ambrette
Musk xylene
1,5-Naphthalenediamine
1,5-Naphthalene diisocyanate
Naphtho[1,2-b]fluoranthene
Naphtho[2,1-a]fluoranthene
Naphtho[2,3-e]pyrene
1-Naphthylamine
1-Naphthylthiourea (ANTU)
Nithiazide
5-Nitro-ortho-anisidine
9-Nitroanthracene
7-Nitrobenz[a]anthracene
000150-68-5
000110-91-8
308068-56-6
000083-66-9
000081-15-2
002243-62-1
003173-72-6
111189-32-3
000203-20-3
000193-09-9
000134-32-7
000086-88-4
000139-94-6
000099-59-2
000602-60-8
020268-51-3
Group
28
Volume
Year1
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
92
92
92
92
1, Sup 7
108
19, Sup 7, 71
92
92
51
41, Sup 7, 71
60
60
30, Sup 7
92
40, Sup 7
8, Sup 7
12, Sup 7
94
33, Sup 7
19, Sup 7
53
47, 71
2010
2010
2010
2010
1987
2016
1999
2010
2010
1991
1999
1994
1994
1987
2010
1987
1987
1987
2010
1987
1987
1991
1999
3
3
3
3
3
3
3
3
3
3
3
3
3
65
65
27, Sup 7
19, Sup 7, 71
92
92
92
4, Sup 7
30, Sup 7
31, Sup 7
27, Sup 7
33, Sup 7
46
1996
1996
1987
1999
2010
2010
2010
1987
1987
1987
1987
1987
1989
Agents Classified by the IARC Monographs, Volumes 1–116
Agent
063041-90-7
000092-93-3
000892-21-7
000059-87-0
000067-20-9
000086-57-7
000581-89-5
020589-63-3
000789-07-1
037620-20-5
071267-22-6
000086-30-6
000156-10-5
029291-35-8
055557-01-2
055557-02-3
030310-80-6
085502-23-4
007519-36-0
000099-08-1
000099-99-0
000099-55-8
000804-36-4
118399-22-7
025038-54-4
022966-79-6
6-Nitrobenzo[a]pyrene
4-Nitrobiphenyl
3-Nitrofluoranthene
Nitrofural (Nitrofurazone)
Nitrofurantoin
1-Nitronaphthalene
2-Nitronaphthalene
3-Nitroperylene
2-Nitropyrene
N'-Nitrosoanabasine (NAB)
N'-Nitrosoanatabine (NAT)
N-Nitrosodiphenylamine
para-Nitrosodiphenylamine
N-Nitrosofolic acid
N-Nitrosoguvacine
N-Nitrosoguvacoline
N-Nitrosohydroxyproline
3-(N-Nitrosomethylamino)propionaldehyde
N-Nitrosoproline
Nitrotoluenes
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
46
4, Sup 7
33, Sup 7
50
50
46
46
46
46
37, Sup 7, 89
37, Sup 7, 89
27, Sup 7
27, Sup 7
17, Sup 7
85
85
17, Sup 7
85
17, Sup 7
65
1989
1987
1987
1990
1990
1989
1989
1989
1989
2007
2007
1987
1987
1987
2004
2004
1987
2004
1987
1996
5-Nitro-ortho-toluidine
Nitrovin
Nodularins
Nylon 6
Oestradiol mustard
Opisthorchis felineus (infection with)
Organic polymeric materials
Orthopaedic implants of complex composition and
cardiac pacemakers
Oxyphenbutazone
Paint manufacture (occupational exposure in)
Palygorskite (Attapulgite)(short fibres, < 5 micrometres)
Paracetamol (Acetaminophen)
Parasorbic acid
Patulin
Penicillic acid
Pentachloroethane
3
3
3
3
3
3
3
3
48
31, Sup 7
94
19, Sup 7
9, Sup 7
61
74
74
1990
1987
2010
1987
1987
1994
1999
1999
3
3
3
3
3
3
3
3
13, Sup 7
47
68
73
10, Sup 7
40, Sup 7
10, Sup 7
41, Sup 7, 71
1987
1989
1997
1999
1987
1987
1987
1999
000129-20-4
012174-11-7
000103-90-2
010048-32-5
000149-29-1
000090-65-3
000076-01-7
Group
29
Volume
Year1
CAS No
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
Group
052645-53-1 Permethrin
000198-55-0 Perylene
060102-37-6 Petasitenine
Petroleum solvents
000085-01-8 Phenanthrene
000156-51-4 Phenelzine sulfate
000103-03-7 Phenicarbazide
000108-95-2 Phenol
000050-33-9 Phenylbutazone
000108-45-2 meta-Phenylenediamine
000106-50-3 para-Phenylenediamine
000135-88-6 N-Phenyl-2-naphthylamine
000090-43-7 ortho-Phenylphenol
000213-46-7 Picene
001918-02-1 Picloram
000051-03-6 Piperonyl butoxide
009003-01-4 Polyacrylic acid
Polychlorinated dibenzo-para-dioxins (other than 2,3,7,8tetrachlorodibenzo-para-dioxin)
Polychlorinated dibenzofurans
(see 2,3,4,7,8-Pentachlorodibenzofuran)
009010-98-4 Polychloroprene
009002-88-4 Polyethylene
009016-87-9 Polymethylene polyphenyl isocyanate
009011-14-7 Polymethyl methacrylate
009003-07-0 Polypropylene
009003-53-6 Polystyrene
009002-84-0 Polytetrafluoroethylene
009009-54-5 Polyurethane foams
009003-20-7 Polyvinyl acetate
009002-89-5 Polyvinyl alcohol
009002-86-2 Polyvinyl chloride
009003-39-8 Polyvinyl pyrrolidone
004548-53-2 Ponceau SX
023746-34-1 Potassium bis(2-hydroxyethyl)dithiocarbamate
002955-38-6 Prazepam
029069-24-7 Prednimustine
000053-03-2 Prednisone
Printing inks
30
Volume
Year1
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
53
92
31, Sup 7
47
92
24, Sup 7
12, Sup 7
47, 71
13, Sup 7
16, Sup 7
16, Sup 7
16, Sup 7
73
92
53
30, Sup 7
19, Sup 7
69
1991
2010
1987
1989
2010
1987
1987
1999
1987
1987
1987
1987
1999
2010
1991
1987
1987
1997
3
69
1997
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7, 71
8, Sup 7
12, Sup 7
66
50
26, Sup 7
65
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1996
1990
1987
1996
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
000051-02-5
000122-42-9
000627-12-3
000115-07-1
087625-62-5
000129-00-0
000110-86-1
085878-62-2
000058-14-0
000117-39-5
000106-51-4
000082-68-8
000050-55-5
000108-46-3
000480-54-6
000081-88-9
000989-38-8
013292-46-1
026308-28-1
122320-73-4
023537-16-8
008047-67-4
000081-07-2
000085-83-6
007782-49-2
000563-41-7
000480-81-9
002318-18-5
015501-74-3
000138-59-0
007631-86-9
000122-34-9
Agent
Group
Proflavine salts
Pronetalol hydrochloride
Propham
n-Propyl carbamate
Propylene
Ptaquiloside
Pulp and paper manufacture
Pyrene
Pyridine
Pyrido[3,4-c]psoralen
Pyrimethamine
Quercetin
para-Quinone
Quintozene (Pentachloronitrobenzene)
Reserpine
Resorcinol
Retrorsine
Rhodamine B
Rhodamine 6G
Rifampicin
Ripazepam
Rosiglitazone
Rugulosin
Rock (stone) wool
Saccharated iron oxide
Saccharin and its salts
(NB: Overall evaluation downgraded to Group 3 with
supporting evidence from other relevant data)
Scarlet Red
Schistosoma mansoni (infection with)
Selenium and selenium compounds
Semicarbazide hydrochloride
Seneciphylline
Senkirkine
Sepiolite
Shikimic acid
Silica, amorphous
Silicone breast implants
Simazine
31
Volume
Year1
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
24, Sup 7
13, Sup 7
12, Sup 7
12, Sup 7
60
40, Sup 7
25, Sup 7
92
77
40, Sup 7
13, Sup 7
73
15, Sup 7, 71
5, Sup 7
24, Sup 7
15, Sup 7, 71
10, Sup 7
16, Sup 7
16, Sup 7
24, Sup 7
66
108
40, Sup 7
43, 81
2, Sup 7
73
1987
1987
1987
1987
1994
1987
1987
2010
2000
1987
1987
1999
1999
1987
1987
1999
1987
1987
1987
1987
1996
2016
1987
2002
1987
1999
3
3
3
3
3
3
3
3
3
3
3
8, Sup 7
61
9, Sup 7
12, Sup 7
10, Sup 7
31, Sup 7
68
40, Sup 7
68
74
73
1987
1994
1987
1987
1987
1987
1997
1987
1997
1999
1999
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
Group
308068-56-6 Single-walled carbon nanotubes (see Carbon nanotubes,
single-walled)
Slag wool
007758-19-2 Sodium chlorite
000148-18-5 Sodium diethyldithiocarbamate
000052-01-7 Spironolactone
009003-54-7 Styrene-acrylonitrile copolymers
009003-55-8 Styrene-butadiene copolymers
000108-30-5 Succinic anhydride
000842-07-9 Sudan I
003118-97-6 Sudan II
000085-86-9 Sudan III
006416-57-5 Sudan Brown RR
006368-72-5 Sudan Red 7B
000127-69-5 Sulfafurazole (Sulfisoxazole)
000057-68-1 Sulfamethazine
(NB: Overall evaluation downgraded to Group 3 with
supporting evidence from other relevant data)
000723-46-6 Sulfamethoxazole
Sulfites
007446-09-5 Sulfur dioxide
002783-94-0 Sunset Yellow FCF
Surgical implants (see Ceramic implants, Dental
materials, Implanted foreign bodies, Organic polymeric
materials, Orthopaedic implants, Silicone breast
implants)
SV40 polyomavirus
022571-95-5 Symphytine
014807-96-6 Talc not containing asbestos or asbestiform fibres
001401-55-4 Tannic acid and tannins
Tea
000846-50-4 Temazepam
008001-50-1 Terpene polychlorinates (Strobane®)
015721-02-5 2,2',5,5'-Tetrachlorobenzidine
Tetrakis(hydroxymethyl)phosphonium salts
000083-67-0 Theobromine
000058-55-9 Theophylline
000062-56-6 Thiourea
000137-26-8 Thiram
32
Volume
Year1
3
3
3
3
3
3
3
3
3
3
3
3
3
3
43, 81
52
12, Sup 7
79
19, Sup .7
19, Sup 7
15, Sup 7
8, Sup 7
8, Sup 7
8, Sup 7
8, Sup 7
8, Sup 7
24, Sup 7
79
2002
1991
1987
2001
1987
1987
1987
1987
1987
1987
1987
1987
1987
2001
3
3
3
3
79
54
54
8, Sup 7
2001
1992
1992
1987
3
3
3
3
3
3
3
104
31, Sup 7
42, Sup 7, 93
10, Sup 7
51
66
5, Sup 7
2013
1987
2010
1987
1991
1996
1987
3
3
3
3
3
3
27, Sup 7
48, 71
51
51
79
53
1987
1999
1991
1991
2001
1991
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
Group
000108-88-3
089778-26-7
021259-20-1
000052-68-6
000545-06-2
000071-55-6
000079-00-5
000102-71-6
001954-28-5
001582-09-8
090370-29-9
000137-17-7
000088-05-1
003902-71-4
000118-96-7
000217-59-4
000068-76-8
000545-55-1
000051-18-3
000115-96-8
038571-73-2
000057-39-6
000128-66-5
000143-67-9
002068-78-2
009003-22-9
000075-35-4
009011-06-7
000075-38-7
000088-12-0
025013-15-4
012001-79-5
013983-17-0
001330-20-7
000095-68-1
000095-78-3
000085-84-7
000131-79-3
Toluene
Toremifene
T2-Trichothecene
Trichlorfon
Trichloroacetonitrile
1,1,1-Trichloroethane
1,1,2-Trichloroethane
Triethanolamine
Triethylene glycol diglycidyl ether
Trifluralin
4,4',6-Trimethylangelicin plus ultraviolet A radiation
2,4,5-Trimethylaniline
2,4,6-Trimethylaniline
4,5',8-Trimethylpsoralen
2,4,6-Trinitrotoluene
Triphenylene
Tris(aziridinyl)-para-benzoquinone (Triaziquone)
Tris(1-aziridinyl)phosphine oxide
2,4,6-Tris(1-aziridinyl)-s-triazine
Tris(2-chloroethyl) phosphate
1,2,3-Tris(chloromethoxy)propane
Tris(2-methyl-1-aziridinyl)phosphine oxide
Vat Yellow 4
Vinblastine sulfate
Vincristine sulfate
Vinyl chloride-vinyl acetate copolymers
Vinylidene chloride
Vinylidene chloride-vinyl chloride copolymers
Vinylidene fluoride
N-Vinyl-2-pyrrolidone
Vinyl toluene
Vitamin K substances
Wollastonite
Xylenes
2,4-Xylidine
2,5-Xylidine
Yellow AB
Yellow OB
33
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
Volume
47, 71
66
31, Sup 7
30, Sup 7
52, 71
20, Sup 7, 71
52, 71
77
11, Sup 7, 71
53
Sup 7
27, Sup 7
27, Sup 7
40, Sup 7
65
92
9, Sup 7
9, Sup 7
9, Sup 7
48, 71
15, Sup 7, 71
9, Sup 7
48
26, Sup 7
26, Sup 7
19, Sup 7
39, Sup 7, 71
19, Sup 7
39, Sup 7, 71
19, Sup 7, 71
60
76
68
47, 71
16, Sup 7
16, Sup 7
8, Sup 7
8, Sup 7
Year1
1999
1996
1987
1987
1999
1999
1999
2000
1999
1991
1987
1987
1987
1987
1996
2010
1987
1987
1987
1999
1999
1987
1990
1987
1987
1987
1999
1987
1999
1999
1994
2000
1997
1999
1987
1987
1987
1987
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
Agent
Group
000315-18-4 Zectran
001318-02-1 Zeolites other than erionite (clinoptilolite,
phillipsite,mordenite, non-fibrous Japanese zeolite,
synthetic zeolites)
012122-67-7 Zineb
000137-30-4 Ziram
000105-60-2 Caprolactam
000103-90-2 Acetaminophen (see Paracetamol)
Alpha particles (see Radionuclides)
012174-11-7 Attapulgite (see Palygorskite)
Beta particles (see Radionuclides)
000494-03-1 N,N-Bis(2-chloroethyl)-2-naphthylamine (see
Chlornaphazine)
000117-81-7 Bis(2-ethylhexyl) phthalate (see Di(2-ethylhexyl)
phthalate)
Boot and shoe manufacture and repair (see Leather dust,
Benzene)
000055-98-1 1,4-Butanediol dimethanesulfonate (see Busulfan)
Chimney sweeping (see Soot)
013909-09-6 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea
(see Methyl-CCNU)
000107-30-2 Chloromethyl methyl ether (see Bis(chloromethyl)ether;
chloromethyl methyl ether)
Chlorophenols (see Polychlorophenols)
001937-37-7 CI Direct Black 38 (see Benzidine, dyes metabolized to)
002602-46-2 CI Direct Blue 6 (see Benzidine, dyes metabolized to)
016071-86-6 CI Direct Brown 95 (see Benzidine, dyes metabolized to)
059865-13-3 Ciclosporin
008007-45-2 Coal tars (see Coal-tar distillation)
Continuous glass filament (see Glass filament)
001464-53-5 1,2:3,4-Diepoxybutane (see Monographs on 1,3Butadiene)
Diesel engine exhaust (see Engine exhaust, diesel)
Dyes metabolized to benzidine (see Benzidine, dyes
metabolized to)
Foreign bodies (see Surgical implants and other foreign
bodies)
Furniture and cabinet making (see Wood dust)
001303-00-0 Gallium arsenide (see Arsenic and inorganic arsenic
compounds)
Gamma-Radiation (see X- and Gamma-Radiation)
34
Volume
Year1
3
3
12, Sup 7
68
1987
1997
3
3
4
12, Sup 7
53
39, Sup 7, 71
1987
1991
1999
25, Sup 7
1987
92
2010
50, 100A
35, Sup 7
2012
1987
11, Sup 7
1987
25, Sup 7
86, 100C
1987
2012
1
Agents Classified by the IARC Monographs, Volumes 1–116
CAS No
010043-66-0
000505-60-2
000055-98-1
000523-44-4
001936-15-8
000087-86-5
053973-98-1
007664-93-9
010098-97-2
014807-96-6
012070-12-1
007440-48-4
Agent
Group
Gasoline engine exhaust (see Engine exhaust, gasoline)
High-temperature frying (see Frying)
Hot mate (see Very hot beverages)
Household combustion of biomass fuel (see Biomass
fuel, indoor emissions from household combustion of)
Household combustion of coal (see Coal, indoor
emissions from household combustion)
Human herpesvirus type 4 (see Epstein-Barr virus)
Human herpesvirus type 8 (see Kaposi sarcoma
herpesvirus)
Involuntary smoking (see Tobacco smoke, second-hand)
Iodine-131 (see Radioiodines)
Mustard gas (see Sulfur mustard)
Myleran (see Busulfan)
Nickel refining (see Nickel compounds)
Oestrogen (see Estrogen)
Oral contraceptives, combined estrogen-progestogen
(see Estrogen-progestogen oral contraceptives)
Orange I (see CI Acid Orange 20)
Orange G (see CI Orange G)
Paving and roofing with coal-tar pitch (see Coal-tar pitch)
Pentachlorophenol (see Polychlorophenols)
Poligeenan (see Carrageenan, degraded)
Strong-inorganic-acid mists containing sulfuric acid (see
Acid mists)
Strontium-90 (see Fission products)
Sunlamps and sunbeds (see Ultraviolet-emitting tanning
devices)
Talc containing asbestiform fibres (see Asbestos)
Toxins derived from certain Fusarium species (see
Fusarium)
Tungsten carbide with cobalt metal (see Cobalt metal
with tungsten carbide)
Urethane (see Ethyl carbamate)
Wood smoke (see Biomass fuel, indoor emissions from
household combustion)
1
Year of publication in print; if published in electronic format only, this is stated as “online”
Last update: 16 September 2016
35
Volume
Year1
11
1976
92
53, 71
2010
1999
42, Sup 7
1987