CURRICULUM VITAE NAME Staff ID DESIGNATION NATIONALITY Dr. Pek Chin LOH 10218 Assistant Professor Malaysian CURRENT AFFILIATION Biomedical Science Department Facullty of Science Universiti Tunku Abdul Rahman 31900 Kampar, Perak campus Tel: 05-4688888 ext.4519 email: lohpc@utar.edu.my AREA of EXPERTISE Gene cloning, functional genomics, plant-microbe interaction and diseases enzyme biochemistry, biomineralization activities of microbes, protein engineering, protein-protein interactions, bioinformatics RESEARCH INTEREST 1. Analysis of the biochemical properties and regulation of GTPase activities 2. Functional study of GTPases and regulation of ribosome biogenesis 3. Biomineraliztion: carbonation and silification activities of bacteria 4. Plant-microbe interaction: screening of microbes with anti-fungal activities for potentail treatment of crops-related diseases EDUCATION TERTIARY 2007 Sept Nara Institute of Science and Technology, Japan Ph.D (Functional Genomics) Supevisor : Prof. Naotake OGASAWARA 2002 March Nara Institute of Science and Technology, Japan Master of Biological Science Supevisor : Prof. Naotake OGASAWARA 1995 April University of Malaya, Malaysia Bachelor of Science ( Hons. ) Microbiology FYP Supevisor : Prof. Coy Choke HO TEACHING EXPERIENCE 2010 Aug- present Assistant Professor, UTAR Subjects: Medical Microbiology & Parasitology, Microbiology, Protein & Proteomics, Structure Biochemistry/Biomolecules 2006 May - 07 Feb 2005 May - 06 Feb 2004 May - 05 Feb Teaching Assistant, Nara Inst. of Science and Technology Teaching Assistant, Nara Inst. of Science and Technology Research Assistant, Nara Inst. of Science and Technology 1 WORKING EXPERIENCE 2007 Nov - 2009 Dec Reseacher Nara Institute of Science and Technology Laboratory of Plant Molecular Genetics (Prof. Shimamoto Ko) -Molecular characterization of Rac GTPase and Nucleotide Binding-Leucine Rich Repeat (NBS-LRR)-like Resistant genes in rice 1996 May- 1998 March Quality Assurance Executive Central Malaya Printing and Carton Manufacturer Ltd. Co. Section 19, Petaling Jaya 1995 June -1996 April Quality Assurance Executive Nationwide PPS Sdn. Bhd. Batu 3, Shah Alam ACHIEVEMENT Conferences/Seminars Development of a Broad-Host Range Acetosyringone-inducible Heterologous Protein Expression System. 20th MSMBB Scientific Meeting & MSMBB 25th Anniversary . Malaysian Society for Molecular Biology and Biotechnology (MSMBB). Auditorium Research Management & Innovation Complex, Kuala Lumpur. June 26-27, 2013 Genetic engineering of Agrobacterium tumefaciens forenhanced plant transformation. National Biotechnology Seminar 2013. National Institute of Biotechnology Malaysia. Hotel Equatorial, Penang. June 6-8, 2013 Molecular characterization of GTPase YqeH and its interactant S4, a 30S ribosomal protein. UTAR National Postgraduate Fundamental and Applied Sciences Seminar 2013. Heritage Hall, Perak campus. May 13-14, 2013 Characterization of "anti-Ganoderma' activities of bacteria isolated from biofertilizer. K. M. Tee and P.C. Loh. UTAR Scientific Mini Symposium I (USMS I), In Conjunction with Agricultural Teachnology Seminar Series VI . Concourse, Faculty of Science, UTAR Perak campus. November 24, 2012 (Awarded as Best Poster: Consolation prize) Characterization of "anti-Ganoderma' activities of bacteria isolated from different fertilizers. C. R. Phang and P.C. Loh. UTAR Scientific Mini Symposium I (USMS I), In Conjunction with Agricultural Teachnology Seminar Series VI. Concourse, Faculty of Science, UTAR Perak campus. November 24, 2012 (Awarded as Best Poster: Third prize) 2 Characterization of microorganisms and antimicrobial activity of lemongrass based garbage enzymes. L. F. Lee and P.C. Loh. The 3rd Malaysian Symposium on Biomedical Sciences. Dentistry Faculty, University of Malaya, Kuala Lumpur. May 19-20, 2012. The GTPase YqeH Participates in Biogenesis of the 30S Ribosomal Subunit in Bacillus subtilis. Pek Chin LOH, Takuya MORIMOTO, Taku OSHIMA and Naotake OGASAWARA. MY1BIO Conference 2010 Accelerating Biotechnology Through Innovative Research . Berjaya Times Square Hotel, Kuala Lumpur. Oct 30-31, 2010. ORAL 2.3, p.50. Organized by MSMBB, MSBMB, and MSM. Invited seminar: Pek Chin Loh. The GTP-binding protein YqeH participates in biogenesis of the 30S ribosomal subunit in Bacillus subtilis. Institute of Biological Sciences, University Malaya, Kuala Lumpur, Malaysia. April 20, 2008 The GTP-binding protein YqeH participates in biogenesis of the 30S ribosomal subunit in Bacillus subtilis . Pek Chin Loh, Takuya Morimoto, Yoshitaka Matsuo, Taku Oshima and Naotake Ogasawara. 4th Conference on Functional Genomics of Gram-Positive Microorganisms Tirrenia, Pisa, Italy. June 24-28, 2007. The GTP-binding protein YqeH engages in the biogenesis of 30S ribosome subunit in Bacillus subtilis. Pek Chin Loh, Takuya Morimoto, Yoshitaka Matsuo, Taku Oshima and Naotake Ogasawara. Translational Control 2006 , Cold Spring Harbor Laboratory, New York, USA. September 6-10, 2006 Functional analysis of YqeH, an essential GTP-binding protein of Era/Obg family in Bacillus subtilis . Pek Chin Loh, Takuya Morimoto, Yoshitaka Matsuo and Naotake Ogasawara. The 28 th Annual Meeting of the Molecular Biology Society of Japan , Fukuoka. December 7-10, 2005. Functional analysis of YqeH, an essential GTP-binding proteins of Era/Obg family in Bacillus subtilis. Pek Chin Loh, Takuya Morimoto, Yoshitaka Matsuo, and Naotake Ogasawara. 3rd Conference of Functional Genomics of Gram Positive Microorganism , San Diego, California, USA. June 12-16, 2005. Functional analysis of essential GTP-binding protein of Era/Obg family in Bacillus subtilis . Pek Chin Loh, Takuya Morimoto, Yoshitaka Matsuo and Naotake Ogasawara. NAIST COE International Symposium , Nara. January 17-19, 2005. Biochemical and genetics studies of the essential GTP-binding proteins of Era/Obg family in Bacillus subtilis . Pek Chin Loh, Takuya Morimoto, Yoshitaka Matsuo and Naotake Ogasawara. The 27 th Annual Meeting of the Molecular Biology Society of Japan , Kobe. December 8-11, 2004. 3 Biochemical and genetics studies of the essential GTP-binding proteins of Era/Obg family in Bacillus subtilis . Pek Chin Loh, Takuya Morimoto, Yoshitaka Matsuo and Naotake Ogasawara. The 5 th SLB-KRIBB-NAIST Joint Symposium . November 14, 2003. Korea University, Incheon, Korea. Functional analysis of the essential GTP-binding proteins of Era/Obg family in Bacillus subtilis . Pek Chin Loh, Takuya Morimoto, Yoshitaka Matsuo and Naotake Ogasawara. 2nd NAIST Bio-COE International Symposium . Awaji Island, Japan. January 20, 2004. Biochemical study of the essential GTP-binding proteins of Era/Obg family in Bacillus subtilis . Pek Chin Loh, Takuya Morimoto, Yoshitaka Matsuo and Naotake Ogasawara. 2nd Conference of Functional Genomics of Gram-positive Microorganism . Baveno, Italy. June 22-27, 2003. List of Publication P. C. Loh, K.H. Chiang, C.R. Phang, K.M. Tee and H.L. Wong (2012). Isolation and characterization of soil microorganisms with anti-Ganoderma properties. XV International Congress on Molecular Plant-Microbe Interaction . Kyoto, Japan (ISI-Thomson 0-9654625-1-X) H.L. Wong, M. Isshiki, P.C. Loh, W.K.Toh, T. Kawasaki, K. Shimamoto (2012). Functional analysis of a Rice AAA-Type ATPase, an attentuator of programmed cell death. XV International Congress on Molecular Plant-Microbe Interaction . Kyoto, Japan. (ISI-Thomson 0-9654625-1-X) Pek Chin Loh, Takuya Morimoto, Yoshitaka Matsuo, Taku Oshima and Naotake Ogasawara (2007). The GTP-binding protein YqeH participates in biogenesis of the 30S ribosomal subunit in Bacillus subtilis . Genes Genet. Syst. 82, 82 281-289 Matsuo, Y.,, Oshima T., Loh, P.C., Morimoto, T., and Ogasawara, N. (2007). Isolation and characterization of a dominant negative mutant of Bacillus subtilis GTP-binding protein, YlqF, essential for biogenesis and maintenance of the 50S ribosomal subunit. J . Biol. Chem. 282, 282 25270-25277 Matsuo, Y., Morimoto, T., Kuwano, M., Loh, P.C., Oshima, T., and Ogasawara, N. (2006) The GTP-binding protein YlqF participates in the late step of 50S ribosomal subunit assembly in Bacillus subtilis . J. Biol. Chem. 281, 281 8110-8117 Morimoto, T., Loh, P.C., Hirai, T., Asai, K., Kobayashi, K., Moriya, S., and Ogasawara, N. (2002). Six GTP-binding proteins of the Era/Obg family are essential for cell growth in Bacillus subtilis . Microbiology 148: 3539-52 Lee P.C., Loh P.C. and Ho C.C.(1997). Production of tylosin by Streptomyces fradiae in palm oil medium. World Journal of Microbiology and Biotechnology 13(1): 69-71. Lee P.C., Loh P.C. and Ho C.C.(1996). Production of tylosin by Streptomyces fradiae in palm oil medium. Ann. Rep of ICBiotech. Vol. 19, p 642-646. 4 RESEARCH PROJECT ON-GOING -Functional characterization of GTPase YqeH and and its involvement in biogenesis of 30S ribosome biogenesis" -Isolation and characterization of soil microorganisms with anti-Ganoderma properties. COMPLETED: -Biochemical analyses of the GTPases of Obg/Era family in Bacillus subtilis -Functional characterization of GTPase YlqF and its involvement in late step assembly of 50S ribosome biogenesis -Molecular characterization of Nucleotide Binding-Leucine Rich Repeat (NBS-LRR)like Resistant genes in rice CONSULTANCY: -Characterization of bacteria with anti-Fusarium and anti-Ganoderma actvities -Generation of biofertilizer from kitchen wastes fermentation RESEARCH GRANT ON-GOING 1. UTAR Research Fund: Fund Molecular characterization of GTPase YqeH and its interactant ribosomal protein S4 in regulating the biogenesis of 30S ribosomal subunit in Bacillus subtilis (P.C. Loh, PI) 2. MOHE FRGS: Metal Binding Study of Rice Metallothionein. K.E. Neo (PI), UTAR. Collaborators: H.L. Wong, P.C. Loh and C.H. Ng PROFESSIONAL MEMEBERSHIP 1. International Society of Molecular Plant-Microbe Interactions 2. Malaysian Society for Microbiology 5