Centre for Computational Neuroscience and Cognitive Robotics – CN-CR Linking neuroscience with robotics. 3 About the Centre Contents About the Centre Key projects Our research groups Who will benefit from the Centre? Research-led teaching 2 4 9 10 11 The University of Birmingham is at the forefront of research to link the science of how the human brain functions with the field of robotics. We have recently announced plans for a multi-million pound investment in this area with a new centre for Computational Neuroscience and Cognitive Robotics, unique in the UK, opening in 2010. This centre will combine state-of-the-art brain imaging and cognitive neuroscience with robotics. One applied aim of this will be to translate neuroscience to facilitate the rehabilitation of brain lesioned patients, as well as more generally advancing the field by implementing psychological theories in robotic systems. Hosting a suite of cognitive neuroscience and robotics laboratories, the Centre will focus on developing a better understanding of brain function and learning. This will be translated into innovative treatments for brain injured patients and those with degenerative or developmental neurological disorders. It will also focus on using this improved understanding to develop new kinds of intelligent control for robots that are inspired by the way the brain works, and to use these and existing techniques in intelligent robotics to develop assistive and rehabilitative robots for brain impaired or motor disabled patients. The Centre, served by a core MRI facility, will provide a centre of excellence for applied cognitive neuroscience and cognitive robotics, with translational applications in the areas of n brain injury n ageing n developmental and adult neurological disorders n assistive and rehabilitative robotics Computational Neuroscience and Cognitive Robotics There are around 250,000 cases of brain injury per year in the UK, through medical conditions such as stroke and head trauma and similar numbers of individuals who are diagnosed with degenerative neurological change in disorders such as Alzheimer’s and Parkinson’s Disease. Brain injury is the leading cause of severe disability in the UK, costing the National Health Service around £2.8 billion a year– a cost which is rising due to better initial medical intervention after stroke and brain injury, as people live longer but with a disability, and due to generally increasing life expectancy. Connecting with the local region Our links with medical neuroscience in the Queen Elizabeth Hospital near to the University mean that the Centre is in an advantageous position to generate a uniquely integrated approach to brain rehabilitation. We are also developing links with the European robotics industry to exploit the advances made in robotics. Through an existing stroke screening programme run by the University with local hospitals, we have access to a large group of patients with neurological difficulties. This provides our team of researchers with ideal opportunities for work on new treatments to help patients with brain injury interact with external environments and reconnect with skills and abilities which may have been lost to them following injury. The effects of training and rehabilitation programmes which have been facilitated by robotic interventions will be assessed within the Centre, using both existing measures of brain activity and facilitating the development of new measures. We will also be at the forefront of using robotic systems to test theories of biological function, and in using neuro-imaging data to drive robotic systems. The Centre is the only one of its kind in the UK to bring together cognitive neuroscientific, computational and cognitive robotic expertise, aimed at translational neuroscience and advances in assistive robotics. We aim to integrate several interdisciplinary teams to develop a greater understanding of brain function and human and artificial learning which will be translated into innovative treatment for brain injured patients and those with degenerative or developmental neurological disorders. 3 4 Computational Neuroscience and Cognitive Robotics Key projects Our research into cognitive neuroscience and cognitive robotics involves collaborations between the Schools of Psychology, Computer Science, Biosciences, Medicine, Sport and Exercise Sciences, Mechanical and Manufacturing Engineering, and Electronic, Electrical and Computer Engineering. Our Schools are at the forefront of international work, as shown by their performance in the RAE exercise. In the School of Psychology, 25% of our research activity was judged as ‘world leading’ and 55% as ‘internationally excellent’, placing us third among all 76 UK Psychology departments. The School of Computer Science had 30% of research activity rated ‘world leading’ and 45% as ‘internationally excellent’. We have made cognitive neuroscience and cognitive robotics a key priority in our strategic development plans. Access to state-of-the-art facilities is critical for this rapidly developing field and we have been successful in acquiring high resolution facilities both for measuring and intervening in brain activity, equipment awards for electro-encephalography (EEG), Trans-cranial Magnetic Stimulation (TMS), eye movement and kinematic motion analysis. We also have advanced platforms for robotics including multi-fingered, lightweight robot hands; robot arms; and mobile robots to support a wide range of investigations. Applied neuropsychological research is supported by the Stroke Research Network, which facilitates access to 10 hospital sites across the West Midlands where our stroke screening programme takes place. Through this programme we have one of the largest and best characterised groups of neurological patients in the UK, with details about their cognitive profile and their neurological status. In addition to this we have established panels of healthy elderly participants and children with neuro-developmental disorders. We work closely with medical neuroscience in the existing Queen Elizabeth Hospital, and Computational Neuroscience and Cognitive Robotics Current projects Our projects span from basic work on understanding brain function, through using advanced imaging, robotic devices and virtual reality environments to promote recovery in neurological patients, to applied work on developing intelligent robots. will continue in the new hospital where we will have laboratory facilities on site. The School of Computer Science houses one of the leading robotics groups in the UK with an outstanding reputation for work on control architectures and substantial external research funding. Our scientists are already in close collaboration with researchers in Psychology working on attention, perception and action with the aim being to simulate human control systems in robots, while also using robotic implementations to test psychological theories. Funding for the Centre totals around £7 million and comes from a wide range of sources: all relevant UK Research Councils (BBSRC, EPSRC, ESRC, MRC), UK charities (the Stroke Association, the Wellcome Trust), international bodies (the EU, the Human Science Frontier Program). Example of voxel-based morphological analysis demonstrating selective gray-matter lesions for patients with disorders of attention to space and to objects, along with DTI imaging demonstrating common fibre tract damage Neuropsychological screening and rehabilitation Summary: Developing clinically applicable techniques for cognitive screening after brain injury, examining cognitive deficits in relation to brain lesion, using fMRI to develop neural-level models of neurorehabilitation. Principal Investigators: Professor Jane Riddoch with Professor G Humphreys, Dr Pia Rotshtein Funding: MRC and Stroke Association Focus: Predicting neural recovery from multi-modal brain imaging Techniques: Neuropsychology, MRI (structural and functional), computational modelling 5 6 Example : stereoscopic depth responses in the human brain recorded at 7T. Activity in human visual search associated with top-down excitation (red) and active inhibition (blue), extracted from using a neural-network model of human search to predict the FMRI (BOLD) response. Visual perception and the brain Summary: Using advanced pattern classifier systems to distinguish the neural response to different depth cues to assess whether depth information is coded in a common manner. Also uses psychophysical work to characterise how depth cues may be analysed in computer vision and used to create graphic surfaces. Principal Investigators: Professor Z Kourtzi, Dr P Tino and Dr A Welchman Funding: BBSRC, EPSRC, EU Focus: Understanding the neural basis of depth perception Techniques: Psychophysics, fMRI, computational modelling Understanding neural networks through intervention and modelling Summary: Using fMRI with neuropsychological patients and combined with TMS to show the necessary role of different regions with cortical networks, and using computational models to define the functional roles of different regions. Principal Investigators: Professor G Humphreys with Dr H Allen, Dr J Braithwaite, Dr C Mevorach, Professor Z Kourtzi Funding: BBSRC, MRC Focus: Using neuropsychological-fMRI and fMRI-TMS to decompose interacting neural networks, computational modelling. Computational Neuroscience and Cognitive Robotics Example of psychophysical study with robotic control of force Light-point displays used for modelling human action Example of a virtual reality system for visual tactile interaction Predictive perception and action Summary: The role of the cerebellum in forward planning of action studied through robotic systems where force feedback is varied. Principal Investigators: Professors C Miall and A Wing, Dr J Wyatt Funding: BBSRC, Wellcome, HFSPO, EU, DTi Focus: Perception and action Techniques: Human psychophysics, robotics, fMRI The learning brain Summary: Using and developing multi-modal imaging techniques and multi-voxel classifier systems to understand individual differences in perception and learning, and using this to guide procedures for maintaining plasticity across the age ranges. We are also modelling human action. Principal Investigators: Professor Z Kourtzi with Dr A Bagshaw, Dr H Allen, Dr A Welchman, Professor A Wing Funding: BBSRC, EPSRC, ESRC Focus: Understanding and exploiting neural plasticity Techniques: Multi-modal imaging, human psychophysics, computational modelling The feeling brain Summary: Examining the functional and neural mechanisms of sensory feedback in motor control and the role of active movement in sensory discrimination (haptic perception). Principal Investigators: Professor A Wing, with Professor G Humphreys, Dr R Roberts, Professor C Miall, Dr A Welchman, Dr J Wyatt Funding: BBSRC, EU Focus: Understanding sensory-motor interactions in movement control and touch Techniques: Human psychophysics, robotic systems, motion analysis, fMRI 7 8 Computational Neuroscience and Cognitive Robotics Example of EEG-FMRI used to localise the site of epileptic seizures Example of using human-robot interaction to train a robotic system through mirroring action Example output from neural network model Multi-modal imaging techniques Summary: We are developing procedures for multi-modal imaging, combining the time course of EEG with spatial resolution of MRI, and combined MRI and Trans-cranial Magnetic Stimulation to provide improved analyses of neurological disorders and ageing. Principal Investigators: Dr T Arvenitis with Dr A Bagshaw, Professor Z Kourtzi Funding: BBSRC, EPSRC, EU Focus: Developing techniques for multi-model imaging, combining fMRI, EEG, diffusion tensor imaging and magnetic resonance spectroscopy (MRS), applied to understanding cognition after brain injury, epilepsy, in adults and children. Cognitive robotics Summary: Combining the development of robotic systems with human psychophysical studies in order to optimise robotic function while also learning about human systems by testing in robotic models. Also the application of robotic systems to rehabilitation. Principal Investigators: Dr J Wyatt with Drs R Dearden and N Hawes, and Professors A Sloman, G Humphreys, C Miall Funding: EPSRC, EU, NERC Focus: Development of active robotic systems Techniques: Computer science, Artificial Intelligence, Computational modelling, Machine Learning Computational Psychology Lab (CPL) Summary: We develop mathematical and computational models of psychological phenomena – including human visual attention, the selection of action and visually-guided reaching and grasping. Principal Investigators: Dr. Dietmar Heinke with Professor Glyn Humphreys Funding: EPSRC, ESRC, BBSRC Focus: Development of active robotic systems Techniques: neural computation, agent-based modelling, cognitive robotics, behavioural experiments Focus: Visual Object Recognition, Visual Attention, Visual Affordances, Visual movement control, Social Interactions Web-pages: http://dietmar-heinke.co.uk/, www.comp-psych.bham.ac.uk/ Computational Neuroscience and School Cognitive of Biosciences Robotics Our research groups The Centre will bring together six current research groups along with an investment in three new teams (10 posts) through the University’s Strategic Development fund. The new teams are scheduled for appointment over the period 2010–2012. Current groups are as follows: Professors Humphreys and Riddoch, working on neuropsychology, neurorehabilitation and functional brain imaging of vision and attention; Professors Miall and Wing, leading figures in human motor control; Professor Kourtzi, Drs Arvenitis, Bagshaw, Derbyshire, Hansen, Mevorach, Rotshtein and Welchman working on neuro-imaging methods, visual plasticity, visual control of action and learning; Professor Kourtzi, Drs Allen and Heinke, working on the computational neuroscience of ageing; Drs Wyatt, Schofield, Dearden and Hawes who work on cognitive robotics and visual perception. Dr Tino, Professor Kourtzi, Dr Dearden and Professor Jeffreys working on machine learning for intepretation of imaging and EEG data. The Centre acts as the hub for a number of independent research fellows including a Royal Society Newton Fellow (Dr Jie Siu), a BBSRC David Phillips Fellow (Dr Andrew Welchman), Leverhulme Trust and British Academy research fellows (Drs Pia Rotshtein and Roberta Roberts) and Roberts research fellows (Allen, Bagshaw, Braithwaite, Hansen). Leading players in Birmingham (Professors Glyn Humphreys, Zoe Kourtzi, Dr Ian Apperly, Dr Andrew Welchman) have won prestigious personal awards (BPS President’s Award and Cognitive Psychology Prize, Vision Science Society Young Investigator, Experimental Psychology Prize, von Humboldt Fellowship, Pfizer and Attemto prizes). There are Royal Society collaborative grants (Humphreys, Heinke) with leading computational and cognitive neuroscience groups in Barcelona and Beijing, and two EU training networks and HFSPO grants which include collaborations with the Max Planck Institute for Biological Cybernetics (Tübingen), and with computational neuroscientists at Amsterdam, Antwerp, Barcelona, Ben Sheeva Israel, and Johns Hopkins Baltimore, Marseille, Paris and University College London. The Director of the Centre, Professor Glyn Humphreys, is a Fellow of the British Academy and holds a Royal Society Wolfson Merit Award. The incoming groups will bring in additional new expertise in: computational neuroscience and brain-computer interfaces, functional MRI (fMRI) and EEG methods development and cognitive robotics, to add to our already strong internationally-competitive base. 10 9 10 Computational Neuroscience and Cognitive Robotics Who will benefit from the Centre? Research within the CN-CR Centre is relevant to a wide range of user groups: n stroke victims, individuals with traumatic n n n n n brain injury and degenerative disease (eg, Alzheimer’s and Parkinson’s Disease) neurology, geriatric medicine, neuroradiology, medical physics brain rehabilitation services (physiotherapy, occupational therapy, speech therapy) designers of computer-assisted devices and environments designers of virtual reality training systems, serious gaming designers of intelligent robotic systems, automated vehicles Computational Neuroscience and Cognitive Robotics Research-led teaching CN-CR is a leading centre for training in the field of computational neuroscience (ranging from modelling neuronal data to brain imaging and cognitive rehabilitation) and cognitive robotics. There are currently 40 PhD students associated with the Centre and the Centre is developing a new Masters programme (MRes) in CN-CR, which offers unique training spanning both neuroscience and robotics. There are associated MRes courses in Brain Imaging and MSc courses in Natural Computation. Learn more n Professor Glyn Humphreys, Cognitive Psychology, g.w.humphreys@bham.ac.uk n Professor Chris Miall, Head of Psychology, r.c.miall@bham.ac.uk nDr Jeremy Wyatt, School of Computer Science, j.l.wyatt@bham.ac.uk n Carly Talbot, Administrative enquiries, c.m.talbot@bham.ac.uk tel: +44 (0)121 414 2752 www.cncr.bham.ac.uk 11 Edgbaston, Birmingham, B15 2TT, United Kingdom www.bham.ac.uk 4427 © University of Birmingham 2010. Printed on a recycled grade paper containing 100% post-consumer waste. 1 School of Biosciences