Publications January – December 2008 K. DASGUPTA 1. Keyhan G, Rahme E, Grover S, Dasgupta K. Weight change during diet and exercise interventions among overweight adults with Type 2 Diabetes: Results of a chart review [Original research article]. Canadian Journal of Diabetes 2008; 32(4):255-9. 2. Lysy Z, Da Costa D, Dasgupta K. The Association of Physical Activity and Depression in the context of Type 2 Diabetes [Review and commentary]. Diabetic Medicine 2008;25(10):1133-41. 3. Ng E, Dasgupta K, Johnson J. A new algorithm to differentiate diabetic respondents from the Canadian Community Health Survey Cycle 1.1 by Type (types 1, 2, and gestational) [Original research article]. Health Reports 2008;19(1):71-9. 4. Nguyen N, Rahme E, Dasgupta K. Acute exercise-induced glucose change during an exercise program in type 2 diabetes [Original research article]. Journal of Cardiopulmonary Rehabilitation and Prevention 2008;28(2):122-7. 5. Rahme E, Dasgupta K, Burman M, Hongjun Y, Bernatsky S, Berry G, Nedjar H, Kahn SR. Postdischarge thromboprophylaxis and mortality risk after hip- or kneereplacement surgery [Original research article]. Canadian Medical Association Journal 2008;178(12):1545-54. 6. Rahme E, Dasgupta K, Turecki G, Nedjar H, Galbaud du Fort G. Risks of suicide and poisoning among elderly patients prescribed selective serotonin reuptake inhibitors: a retrospective cohort study [Original research article]. The Journal of Clinical Psychiatry 2008;69(3):349-57. S. DASKALOPOULOU 1. Tessier A, Mayo NE, Daskalopoulou SS, Finch L. Assessing Co-morbidity: the Development and Preliminary Validation of the Stroke Specific Functional Outcome Comorbidity Index. Arch Phys Med Rehabil 2008;89(7):1276-1283. 2. Daskalopoulou SS, Pathmarajah M, Kakkos SK, Daskalopoulos ME, Holloway PA, Mayo NE, Mikhailidis DP, Geroulakos G. Association between ankle-brachial index and risk factor profile in newly diagnosed patients with peripheral arterial disease. Circ J 2008;72(3):441-448. 3. Daskalopoulou SS, Richard H, Pilote L. Sex differences in health services utilization and symptomatology before the first acute myocardial infarction. Canadian Journal of General Internal Medicine 2008 Nov;3(4):184-186. 4. Daskalopoulou, SS. Stopping statins in CHD patients. European Journal Of Cardiovascular Prevention & Rehabilitation 2008;15(6):744-744. K. FLEGEL 1. Attaran A, MacDonald N, Stanbrook MB, Sibbald B, Flegel K, Kale R, Hebert PC. Listeriosis is the least of it [Editorial] CMAJ 2008;179:739-40. 2. Sibbald B, Flegel K. Integrity at the Croation Medical Journal [Editorial] CMAJ 2008;178:1637-38. 3. Miettinen OS, Flegel KM, Steurer J. Clinical diagnosis of pneumonia, typical of experts. J Eval Clin Practice 2008;14:343-350. 4. Flegel K, Hebert PC, Stanbrook MB, Sibbald B, MacDonald N, Attaran A. Getting to the electronic medical record [Editorial] CMAJ 2008;178:531. 5. Flegel K, MacDonal N, Hebert PC, Stanbrook MB, Attaran A. Decision-making capacity in an age of control [Editorial] CMAJ 2008;178:127. 6. Flegel K, Hebert PC, MacDonald N, Stanbrook MB, Sibbald B, Attaran A. Is it time for another medical curriculum revolution? [Editorial] CMAJ 2008;178:11 7. Attaran A, Walker RB, Hebert PC, Stanbrook MB, Flegel K, MacDonald N. Shoppers drug mart or poachers drug mart? [Editorial] CMAJ 2008;178:265-66. S. GROVER 1. Grover SA, Coupal L, Lowensteyn I. Determining the Cost-Effectiveness of Preventing Cardiovascular Disease: Are Estimates Calculated Over the Duration of a Clinical Trial Adequate? Can J Cardiol 2008;24(4):261-266. 2. Padwal RJ, Hemmelgarn BR, Khan NA, Grover S, McAlister FA, McKay DW, Wilson T, Penner B, Burgess E, Bolli P, Hill MD, Mahon J, Myers MG, Abbott C, Schiffrin EL, Honos G, Mann K, Tremblay G, Milot A, Cloutier L, Chockalingam A, Rabkin SW, Dawes MD, Touyz RM, Bell C, Burns KD, Ruzicka M, Campbell NR, Lebel M, Tobe SW; Canadian Hypertension Education Program. The 2008 Canadian Hypertension Education Program recommendations for the management of hypertension: Part 1 - blood pressure measurement, diagnosis and assessment of risk. Can J Cardiol. 2008;24:455-63. 3. Khan NA, Hemmelgarn B, Herman RJ, et al. for the Canadian Hypertension Education Program. The 2008 Canadian Hypertension Education Program recommendations for the management of hypertension: Part 2 – therapy. Can J Cardiol 2008;24:465-475. 4. Grover SA, Coupal L, Lowensteyn I. Preventing Cardiovascular Disease Among Canadians: Is the treatment of Hypertension or Dyslipidemia Cost-Effective? Can J Cardiol 2008;24:891-8. 5. Keyhan G, Rahme E, Grover S, Dasgupta K. Food for thought: weight change during diet and exercise interventions among overweight adults with type 2 diabetes. Canadian Journal of Diabetes. 2008;32(4):255-259. L. J. HOFFER 1. Gan R, Eintracht S, Hoffer LJ. Vitamin C deficiency in a university teaching hospital. J Am Coll Nutr. 2008 Jun;27(3):428-33. 2. Hoffer LJ. Vitamin therapy in schizophrenia. Isr J Psychiatry Relat Sci. 2008;45(1):3-10. Review. 3. Hoffer LJ, Levine M, Assouline S, Melnychuk D, Padayatty SJ, Rosadiuk K, Rousseau C, Robitaille L, Miller WH Jr. Phase I clinical trial of i.v. ascorbic acid in advanced malignancy. Ann Oncol. 2008 Nov;19(11):1969-74. S. KAHN 1. Kahn SR, Platt R, McNamara H, Rozen R, Chen MF, Genest J Jr., Goulet L, Lydon J, Seguin L, Dassa C, Masse A, Asselin G, Benjamin A, Miner L, Ghanem A, Kramer MS. Inherited thrombophilia and preeclampsia within a multicenter cohort: the Montreal Preeclampsia Study. Am J Obs Gynecol 2008 Dec 12. [Epub ahead of print]. 2. Rey E, Garneau P, David M, Gauthier R, Leduc L, Michon N, Morin F, Demers C, Kahn SR, Magee LA, Rodger MA. Dalteparin for the prevention of recurrence of placental-mediated complications of pregnancy in women without thrombophilia: A pilot randomized controlled trial. J Thromb Haemost 2008; 7(1):58-64. 3. Kahn SR, Shrier I, Julian JA, Ducruet T, Arsenault L, Miron M-J, Roussin A, Desmarais S, Joyal F, Kassis J, Solymoss S, Desjardins L, Lamping DL, Johri M and Ginsberg JS. Determinants and time course of the post-thrombotic syndrome after acute deep venous thrombosis. Annals Intern Med 2008; 149:698-707. 4. Kahn SR, Shrier I, Kearon C. Physical activity in patients with deep venous thrombosis: A systematic review. Thrombosis Research 2008; 122(6):763-773. 5. Kearon C, Julian JA, Kovacs MJ, Anderson DR, Wells P, Mackinnon B, Weitz JI, Crowther MA, Dolan S, Turpie AG, Geerts W, Solymoss S, van Nguyen P, Demers C, Kahn SR, Kassis J, Rodger M, Hambleton J, Gent M, Ginsberg JS. for the ELATE Investigators. Influence of thrombophilia on risk of recurrent venous thromboembolism while on warfarin: Results from a randomized trial. Blood 2008; 112(12):4432-4436. 6. Rodger MA, Kahn SR, Wells PS, Anderson DA, Chagnon I, Le Gal G, Solymoss S, Crowther M, Perrier A, White R, Vickars L, Ramsay T, Betancourt M and Kovacs MJ. Identifying low risk unprovoked thromboembolism patients who can discontinue long term oral anticoagulants. CMAJ 2008; 179(9):417-426. 7. Shbaklo H, Kahn SR. Long term prognosis after deep venous thrombosis. Curr Opin Hematol 2008;15(5): 494–498. 8. Rodger MA, Paidas M, McLintock C, Middeldorp S, Kahn SR, Martinelli I, Hague W, Montella KR, Greer I. Inherited Thrombophilia and Pregnancy Complications Revisited. Obstet Gynecol 2008, 112(2): 320-324. 9. Kahn SR, Shbaklo H, Lamping DL, Holcroft CA, Shrier I, Miron M-J, Roussin A, Desmarais S, Joyal F, Kassis J, Solymoss S, Desjardins L, Johri M and Ginsberg JS. Determinants of health-related quality of life during the 2 years following deep vein thrombosis. J Thromb Haemost 2008, 6(7):1105-1112. 10. Kearon C, Kahn SR, Agnelli G, Goldhaber S, Raskob GE, Comerota AJ. Antithrombotic therapy for venous thromboembolic disease: ACCP evidence-based clinical practice guidelines (8th edition). Chest 2008, 133(Suppl.6):454S–545S. 11. Fox MA, Kahn SR. Post-thrombotic syndrome after vena cava filter placement: A systematic review. J Vasc Interv Radiol, 2008;19(7):981-985. 12. Rodger MA, Kahn SR, LeGal G, Solymoss S, Chagnon L, Anderson DR, Wells PS and Kovacs J. Inter-observer reliability of measures to assess the post-thrombotic syndrome. Thromb Haemost 2008; 100:164-166. 13. Rahme E, Dasgupta K, Burman M, Yin H, Bernatsky S, Berry G, Nedjar H, Kahn SR. Postdischarge thromboprophylaxis and mortality risk after hip- or knee- replacement surgery. Can Med Assoc J 2008;178(12):1545-1554. 14. O'Donnell MJ, McRae S, Kahn SR, Julian JA, Kearon C, Mackinnon B, Magier D, Strulovich C, Lyons T, Robinson S, Hirsh J, Ginsberg JS. Evaluation of a venous-return assist device to treat severe post-thrombotic syndrome (VENOPTS). A randomized controlled trial. Thromb Haemost. 2008 Mar;99(3):623-629. P. McLEOD 1. McLeod P, Brawer J, Steinert Y, Chalk C, McLeod A Pilot Study Designed to Acquaint Medical Educators with Basic Pedagogic principles. Medical Teacher 2008; 30:92-93 2. McLeod P, Steinert Y, Snell L.: Use of retrospective pre-post assessments in faculty development. Medical Education 2008; 42:543 3. Steinert Y, Boillat M, Meterissian S, Liben S, McLeod P. Developing Successful Workshops: a workshop for Educators. Medical Teacher 2008; 30:328-330 4. McLeod P, Zanelli P, Wiseman J, Chalk C, McLeod A, MacDonald ME: Redesigning Clinical Education for Medical Students: The Emergency Department Complements the In-patient Service.2008; Canadian Journal of General Internal Medicine 2008; 3(2) 87-89. 5. Brawer J, Chalk C, McLeod P. The Pedagogic impact of Exploring Philosophical Concepts in the Basic Health Sciences: The Students’ perspective. Journal of the International Association of Basic Science Educators 2008; 18:28-32 S. MORIN 1. Rebick G, Morin S. The Thinker’s Sign. CMAJ 2008; 179:611. 2. Morin S, Tsang J, Leslie WD. Weight and Body Mass Index Predict Bone Mineral Density and Fractures in Women 40 to 59 years Osteoporosis International 2008; 20:363-370. 3. Bouchard Fortier G, Laramée J, Morin, S. Towards prevention of chronic diseases in women: Practicability of Early Interventions. Canadian Journal of General Internal Medicine 2008; Volume 3 (1): 33-35 L. PILOTE 1. Jackevicius CA, Tu JV, Demers V, Melo M, Cox J, Rinfret S, Kalavrouziotis D, Johansen H, Behlouli H, Newman A, Pilote L. Cardiovascular outcomes after a change in prescription policy for clopidogrel, NEJM 2008;359:1802-10. 2. Thombs BD, Ziegelstein RC, Beck CA, Pilote L. a general factor model for the Beck Depression Inventory-II: validation in a sample of patients hospitalized with acute myocardial infarction. J Psychosom Res 2008;65:115-121. 3. Eisenberg MJ, filion KB, Yavin D, Belisle P, Mottillo S, Joseph L, Gervais A, O’Loughlin J, Paradis G, Rinfret S, Pilote L. Pharmacotherapies for smoking cessation: a meta-analysis of randomized controlled trials. CMAJ 2008;179:135144. Review Erratum in CMAJ 2008;179:802. 4. Pilote L, Beck C, Eisenberg M, Humphries K, Joseph L, Penrod J, Tu V. Comparing Invasive and Non-invasive Management Strategies for Acute Myocardial Infarction Using Administrative Databases. Am Heart J 2008;155:42-8 5. Demers V, Melo M, Jackeviscius C, Cox J, Kalavrouziotis D, Rinfret S, Humphries K, Johansen H, Tu J, Pilote L. Comparison of provincial prescription drug plans and the impact on patients’ annual drug expenditures. CMAJ 2008;178:405-9. 6. Karp I, Abrahamowicz M, Fortin P, Pilote L, Neville C, Pineau C, Esdaile J. Recent corticosteroid use and recent disease activity: Are they independent determinants of coronary heart disease risk factors in systemic lupus erythematosus. Arthritis Rheumatism 2008;31;59:169-175. 7. Balashov K, Feldman D, Savard S, Houde S, Freneete M, Ducharme A, giannetti N, Michel C, Pilote L. Percent Predicted Value for the Six-Minute Walk Test: Using norm-referenced equations to characterize severity in persons with CHF. J of Cardiac Fail 2008;14:75-81. 8. Humphries KH, Pu A, Carere RG, Pilote L. Angina with ‘normal’ coronary arteries – Sex differences in outcomes. Am Heart J 2008;155:375-81. 9. Rinfret S, Behlouli H, Eisenberg M, Humphries K, Tu J, Pilote L. Class Effects of Statins in Elderly Patients with Congestive Heart Failure: A Population-Based Analysis. Am Heart J 2008;155:316-23. 10. Mackie AS, Ionescu-Ittu R, Pilote L, Rahme E, Marelli AJ. Hospital Readmissions in Children with Congenital Heart Disease: A population-based study. Am Heart J 2008;155:577-84. 11. Seda O, Tremblay J, Gaudet D, Brunelle PL, Gurau A, Merlo E, Pilote L, Orlov SN, Boulva F, Petrovich M, Kotchen T, Cowley AW, Hamet P. Systematic GenomeWide Sex Specific Linkage of Cardiovascular traits in French-Canadians. Hypertension 2008;51:1156-62. 12. Karp I, Behlouli H, LeLorier J, Pilote L. Statins and Cancer Risk. 2008;121:302309. 13. Norris CM, Hegadoren KM, Patterson L, Pilote L. Sex differences in prodromal symptoms of patients with acute coronary syndrome: a pilot study. Prog Cardiovasc Nurs. 2008;23:27-31. 14. Karp I, Behlouli H, LeLorier J, Pilote L. Statins and Cancer Risk: decrease or increase. Am J Med. 2008;121:302-9. 15. Pilote L, Abrahamowicz M, Eisenberg MJ, Humphries K, Behlouli H, Tu JV Effect of different angiotensin-converting-enzyme inhibitors on mortality among elderly patients with congestive heart failure. CMAJ. 2008;178:1303-11. 16. Filion KB, Pilote L, Rahme E, Eisenberg MJ.Use of perioperative cardiac medical therapy among patients undergoing coronary artery bypass graft surgery.J Card Surg. 2008;23:209-15. 17. Shrier I, Boivin JF, Platt R, Steele R, Brophy JM, Carnevale F, Eisenberg MJ, Furlan A, Kakuma R, MacDonald ME, Pilote L, Rossignol M. The interpretation of metaanalysis: an objective or subjective process. BMC Medical Informatics and Decision Making. 2008;8:19 18. Rabi DM, Khan NA, Vallee M, Hladunewich MA, Tobe SW, Pilote L. Reporting of sex-based analyses in clinical trials of ACE Inhibitor and Angiotensin Receptor Blocker Efficacy. Can J Cardiol. 2008;24:491-6. E. SCHIFFRIN 1. Schiffrin EL. Editorial commentary: Oxidative stress, NOS and SOD – a matter of imbalance underlies endothelial dysfunction in the human coronary circulation. Hypertension 2008;51:31-32 2. Savoia C, Touyz RM, Amiri F, Schiffrin EL. The Selective Mineralocorticoid Receptor Blocker Eplerenone Reduces Resistance Artery Stiffness in Hypertensive Patients. Hypertension 2008; 51:432-439 3. Bakris G, Hill M, Mancia G, Steyn K, Black HR, Pickering T, De Geest S , Ruilope L, Giles TD, Morgan T, Kjeldsen S, Schiffrin EL, Coenen A, Mulrow P, Loh A, Mensah G. Achieving blood pressure goals globally: five core actions for healthcare professionals. A worldwide call to action. J Human Hypert. 2008; 22:63-70 4. Schiffrin EL. Editorial commentary: New twist to the role of the RAS in heart failure: Aldosterone upregulates renin-angiotensin system components in the brain. Hypertension 2008; 51:622-623 5. Pu Q, Brassard P, Javeshghani DM, Iglarz M, Webb RL, Amiri F, Schiffrin EL. Effects of Combined AT1 Receptor Antagonist/NEP Inhibitor on Vascular Remodeling and Cardiac Fibrosis in SHRSP. J Hypertens. 2008; 26:322-333 6. Touyz RM, Schiffrin EL. Reactive oxygen species and hypertension – a complex association. Antioxidants & Redox Signaling. 2008; 10: 1041-1044 7. Marchesi C, Schiffrin EL. Peroxisome proliferator-activated receptors and the vascular system: beyond their metabolic effects. J Amer Soc Hypert. 2008; 2: 227-238 8. Lemarié CA, Paradis P, Schiffrin EL. New insights on signaling cascades induced by cross-talk between angiotensin II and aldosterone. J Mol Med. 2008; 86:673–678 9. Yokoyama H, Smith RD, Averill DB, Schiffrin EL, Ferrario CM. Reversal of vascular hypertrophy in hypertensive patients through blockade of angiotensin II receptors. J Am Soc Hypert. 2008; 2:165–172 10. Amiri F, Paradis P, Reudelhuber TL, Schiffrin EL. Vascular inflammation in absence of blood pressure elevation in transgenic murine model overexpressing endothelin-1 in endothelial cells. J Hypertens 2008; 26:1102-1109 11. Marchesi C, Paradis P, Schiffrin EL. Role of the renin-angiotensin system in vascular inflammation. Trends Pharmacol Sci (TIPS) 2008; 29:367-374 12. Tabet F, Schiffrin EL, Callera GE, He Y, Yao G, Ostman A, Kappert K, Tonks NK, Touyz RM. Redox-Sensitive Signaling by Angiotensin II Involves Oxidative Inactivation and Blunted Phosphorylation of Protein Tyrosine Phosphatase SHP-2 in Vascular Smooth Muscle Cells From SHR. Circ Res. 2008;103:149-158 13. Viel EC, Benkirane K, Javesghani D, Touyz RM, Schiffrin EL. Xanthine Oxidase and Mitochondria Contribute to Vascular Superoxide Anion Generation in DOCA-Salt Hypertensive Rats. Amer J Physiol (Heart Circ Physiol). 2008;295: H281-H288 14. Schiffrin EL. The flame that lights the fire: Oxidative stress, inflammation and renal damage in Ang II-induced hypertension. Editorial. Hypertension. 2008; 52;205-206 15. Montezano AC, Callera GE, Yogi A, He Y, Tostes RC, Schiffrin EL, Touyz RM. Crosstalk between Aldosterone and Angiotensin II Signaling Promotes Vascular Smooth Muscle Cell Migration Through c-Src-dependent Redox-sensitive RhoA Pathways. Arterioscl Thromb Vasc Biol. 2008;28:1511-1518 16. Mann JFE, Hilgers KF, Veelken R, Schiffrin EL. Chronische Nierenerkrankungen und kardiovaskuläres System (Chronic kidney disease and the cardiovascular system). Internist. 2008;(49)4:413-413 17. Levy B, Schiffrin EL, Mourad JJ, Agostini D, Vicaut E, Safar M, Struijker-Boudier H. Impaired tissue perfusion: a pathology common to hypertension, obesity and diabetes. Circulation. 2008;118:968-976 18. Dhaun N, Goddard J, Kohan D, Pollock D, Schiffrin EL, Webb D. The Role of Endothelin-1 in Clinical Hypertension: 20 years on. Hypertension. 2008;52:452-459 L. SNELL 1. OSWALD A, BELL M, WISEMAN J, SNELL, L. The Current State of Musculoskeletal Clinical Skills Teaching for Pre-Clerkship medical Students. The Journal of Rheumatology (12):2419-2426; 2008 Dec;35. Epub 2008 Oct 15. 2. STEINERT Y, McLEOD P, LIBEN S, SNELL L. Writing for publication in medical education: The benefits of a faculty development workshop and peer writing group. Medical Teacher. 30(8): 280-285, 2008 3. McLEOD P, STEINERT Y, SNELL L. Use of retrospective pre-post assessments in faculty development. Medical Education, 42:543, 2008. 4. WISEMAN J, SNELL L. The Deteriorating Patient: A Realistic but ‘Low-Tech’ Simulation of Emergency Decision-Making. The Clinical Teacher, 5:1-5, 2008. V. TAGALAKIS 1. Tagalakis V, Tamim H. Validating a method that deals with missing drug information in the Saskatchewan Prescription Drug Plan database. Pharmacoepidemiology and Drug Safety 2008; 17:1-7. J. WISEMAN 1. OSWALD A, BELL M, WISEMAN J, SNELL, L. The Current State of Musculoskeletal Clinical Skills Teaching for Pre-Clerkship medical Students. The Journal of Rheumatology (12):2419-2426; 2008 Dec;35. Epub 2008 Oct 15. 2. WISEMAN J, SNELL L. The Deteriorating Patient: A Realistic but ‘Low-Tech’ Simulation of Emergency Decision-Making. The Clinical Teacher, 5:1-5, 2008. B. YOUNG 1. Young, B. Cancer Patterns in Inuit Populations. The Lancet Oncology 9:1124, 2008.