% Shared DNA (expectations) This graphic assumes that relatives share two common ancestors. How would expectations change if there were only one common ancestor? www.isogg.org/wiki/Autosomal_DNA_statistics Kinship - Coancestry vs Covariance Dad (Sire) Mom (Dam) From Grandpa X From Grandma 100 cM Shared chromosome segments Child #1 Child #2 1. What % of the DNA is expected to be shared between the two children? (this is covariance) 2. What would be the expected level of inbreeding in an offspring of Child #1 and Child #2? (this would be equal to their coancestry) 3. If both children are DNA tested (they are humans now), how many cM are expected to be IBD on both chromosomes (full-IBD)? On just one chromosome (half-IBD)? If the test does not distinguish full and half IBD, what is the total cM that are expected to match? Full-sib Covariance Shared chromosome segments A 1A 2 100 cM Expectations Half-IBD 50 cM Full-IBD 25 cM At least one match 75 cM No Match 25 cM X A 3A 4 25 25 Chance of no shared alleles? Child #2 A1A3 A1A4 A2A3 A2A4 Child #1 A1A3 1/16 A1A4 CovFS 2 FS 1 2 2 A 25 1 4 2 D A2A3 A2A4 1/16 1/16 1/16