MUSCULAR SYSTEM: MUSCLE TISSUE AND MUSCLES. FUNDAMENTALS OF ANATOMY & PHYSIOLOGY BY MARTINI, 9TH EDITION, Chapters # 4, 10 & 11 Lab Manual Exercise # 13 NOTE: THIS IS A STUDY GUIDE, NOT AN ALL INCLUSIVE REVIEW. THERE MIGHT BE THINGS NOT COVERED BY THIS STUDY GUIDE THAT MIGHT BE ASKED IN YOUR PRACTICUMS / QUIZZES. STUDENTS ARE RESPONSIBLE FOR READING THEIR TEXBOOK (S) AND FOR ALL THE MATERIAL COVERED DURING THE LABORATORY PERIOD, AS PER THE COURSE SYLLABUS 7/25/2016 2 Competency 5: The Muscular System Upon successful completion of this course, the student will be able to understand the gross and microscopic anatomy of muscles and their physiology by: Recognize the three types of muscle tissue. Describing the location and functions of the microscopic structures of skeletal muscle. 7/25/2016 3 TYPE OF MUSCLE TISSSUES NEUROMUSCULAR JUNCTION (MODEL #1) MIOFIBRIL (MODEL #2) 7/25/2016 4 TYPE OF MUSCLE TISSUES SKELETAL CARDIAC SMOOTH 7/25/2016 5 SKELETAL MUSCLE TISSUE CELLS- LONG CYLINDRICAL STRIATED MULTINUCLEATED LOCATION- SKELETAL MUSCLE COMBINED WITH CONNECTIVE TISSUE & NERVOUS TISSUE FUNCTIONS: 1- MOVE BODY PARTS & STABILIZE THE POSTURE OF THE SKELETON 2- GUARDS ENTRANCE & EXITS TO THE DIGESTIVE, RESPIRATORY, & URINARY TRACTS 3- TO GENERATE HEAT 4- TO PROTECT INTERNAL ORGANS 7/25/2016 6 CARDIAC MUSCLE TISSUE CELLS- ARE SHORT BRANCHED & STRIATED SINGLE NUCLEUS (USUALLY) INTERCONNECTED BY INTERCALATED DISCS LOCATION- HEART FUNCTIONS: 1- CIRCULATES THE BLOOD 2- MAINTAINS BLOOD (HYDROSTATIC) PRESSURE 7/25/2016 7 SMOOTH MUSCLE TISSUE CELLS- SHORT SPINDLE SHAPED NON STRIATED A SINGLE CENTRAL NUCLEUS LOCATION- ENCIRCLES BLOOD VESSELS IN THE WALLS OF THE DIGESTIVE, RESPIRATORY URINARY & REPRODUCTIVE ORGANS FUNCTIONS: 1- MOVES FOOD IN DIGESTIVE TRACT AND FLUIDS IN THE DIGESTIVE, URINARY, AND REPRODUCTIVE TRACTS 2-CONTROLS DIAMETERS OF RESPIRATORY PASSAGEWAYS & BLOOD VESSELS 7/25/2016 8 7/25/2016 ALFONSO A. PINO. MD. 9 ORGANIZATION OF THE CONNECTIVE TISSUE EPIMISYUM PERIMYSIUM ENDOMYSIUM THEY CONVERGE TO FORM: TENDONS APONEUROSES 7/25/2016 10 EPIMYSIUM- A DENSE LAYER OF CONNECTIVE TISSUE THAT SURROUNDS THE ENTIRE MUSCLE. IT SEPARATES THE MUSCLE FROM OTHER TISSUES PERIMYSIUM- IT DIVIDES THE SKELETAL MUSCLE INTO COMPARTMENT IT SURROUNDS THE FASCICLES FASCICLE- A BUNDLE OF MUSCLE FIBERS 7/25/2016 11 7/25/2016 ALFONSO A. PINO. MD. 12 7/25/2016 ALFONSO A. PINO. MD. 13 MODEL #1(MOTOR UNIT) AXON TERMINAL- END PART OF THE AXON OF THE NEURON F- TO RELEASE THE NEUROTRANSMITTER MUSCLE CELLS OR FIBERS- THE WHOLE STRUCTURE WITHOUT THE NEURON F- CONTRACTS TO SHORTEN THE WHOLE MUSCLE NEUROMUSCULAR JUNCTION- AREA IN WHICH THE NEURON & THE MUSCULAR CELL ARE JOINED (A BUMP IN THE MODEL) AXON OF THE MOTOR NEURON- (LIKE A SAUSAGE IN THE MODEL) IT IS A CYTOPLASMATIC EXTENSION OF THE NEURON THAT CARRIES THE NERVE IMPULSE MOTOR UNIT- NEURON + MUSCLE CELL OR FIBER ENDOMYSIUM- IT SURROUNDS THE SARCOLEMMA OR CELL MEMBRANE (THE ROUGH AREA OUTSIDE) MYOFIBRILS- THEY ARE FOUND INSIDE THE MUSCLE FIBERS. THEY CAN NUMBER IN 100’S TO 1000’S AND THEY CONTAIN BUNDLES OF MYOFILAMENTS NUCLEUS OF MUSCLE CELL- IT IS THE CONTROL CENTER OF THE CELL 14 7/25/2016 ALFONSO A. PINO. MD. 15 MODEL #2 (MYOFIBRIL) MITOCHONDRIA-TO PRODUCE ATP (ENERGY) SARCOPLASMIC RETICULUM- IT SURROUNDS THE MYOFIBRIL F- TO STORE CALCIUM FOR MUSCULAR CONTRACTION T TUBULE: CARRIES THE NERVE IMPULSE INSIDE MUSCLE CELL TERMINAL CISTERNA: ENLARGED AREAS OF SARCOPLASMIC RETICULUM THAT RELEASES CALCIUM TRIAD: TERMINAL CISTERNA + T TUBULE 7/25/2016 16 7/25/2016 ALFONSO A. PINO. MD. 17 MYOFILAMENTS- PROTEIN FILAMENTS COMPOSED OF ACTIN & MYOSIN ACTIN- FORMS THE BULK OF THE THIN FILAMENTS MYOSIN- FORMS THE THICK FILAMENTS A BAND- IS DARK AREA COMPOSED MOSTLY OF THICK FILAMENT AND INCLUDING PORTIONS OF THIN FILAMENTS THAT INTERCALATE WITH THEM I BAND- IS LIGHT AREA THAT CONTAINS ONLY THIN IT FILAMENTS EXTENDS FROM A BAND OF ONE SARCOMERE TO THE A BAND OF THE NEXT SARCOMERE H ZONE- A LIGHTER REGION ON THE MID PART OF THE A BAND THAT CONTAINS ONLY THICK FILAMENTS 7/25/2016 18 SARCOMERE- AREA BETWEEN 2 Z LINES SMALL FUNCTIONAL UNIT OF THE MUSCLE FIBER THEY NUMBER MORE OR LESS IN THE 10,000S LINE Z- IT MARKS THE BOUNDARY BETWEEN ADJACENT SARCOMERES IT IS THE POINT OF ATTACHMENT OF THE THIN FILAMENTS 7/25/2016 19 7/25/2016 ALFONSO A. PINO. MD. 20 MARTINI (PG 292) 7/25/2016 ALFONSO A. PINO. MD. 21 CHARTS & MODELS TENDONS- LOCATED AT THE END OF THE MUSCLE THEY JOIN MUSCLES TO BONES LIGAMENTS- THEY JOIN BONE TO BONE APONEUROSES- FLAT SHEETS OF CONNECTIVE TISSUE THAT USUALLY JOIN MUSCLE TO MUSCLE GALEA (EPICRANIAL APONEUROSIS) IT CONNECTS FRONTALIS WITH OCCIPITALIS LUMBAR- IT JOINS MUSCLES OF THE BACK ABDOMINAL- IT JOINS MUSCLES OF THE ABDOMEN 7/25/2016 22 7/25/2016 ALFONSO A. PINO. MD. 23 7/25/2016 ALFONSO A. PINO. MD. 24 7/25/2016 ALFONSO A. PINO. MD. 25 REMEMBER! GO TO THE TUTORING ROOM AND PRACTICE WITH MODELS. SEE INTERACTIVE PHYSIOLOGY CD ROOM 3326. 7/25/2016 26