Unit 8: Application of Genetics
Chapters 11 and 14
Essential Concepts and Skills
1. Understand the principles of genetics.
a. Review Mendel’s principles of dominance,
independent assortment, and segregation.
b. Review key vocabulary of genetics, for example
genotype and phenotype, homozygous and
heterozygous, dominant and recessive traits.
c. Review the steps of meiosis and how it determines
gamete formation.
2. You will be able to use and interpret a karyotype.
a. Sort all 23 pairs of chromosomes and put them in the
correct order.
b. Be able to interpret a karyotype and evaluate for the
presence of certain chromosomal disorders, such as
Down Syndrome, Kleinfelters, and Turners disease.
c. Discuss the difference between dominant and
recessive genetic disorders such as sickle cell anemia,
Tay-sachs disease and Huntington’s disease.
Reading
Chapter 11
pp. 341342; 345;
349-353
3. You will be able to apply the concepts we have been
learning to actual genetic practices.
a. Genetic Engineering – how we use selective breeding
and inbreeding to isolate certain traits.
b. Cloning
c. The genome project (Human and other).
4. You will be able to perform a test cross.
a. Test crosses are used to determine the genotype when
we it is unknown.
b. In order to do a test cross you must be crossing the
unknown individual with an individual of a known
genotype. The known is usually recessive.
c. Once the ratio of the offspring is determined it is then
possible to determine the genotype of the unknown
parent.
pp. 322-330
pp. 319321; 333
5. You will be able to construct and interpret a pedigree.
a. A pedigree chart is used to study the passing of traits
through a number of generations.
b. Pedigrees are most often used to show the inheritance
of desired traits (such as eye color) or of certain
diseases (such as sickle cell anemia).
pp. 342-343
Assessments:
 Build a Baby
 Karyotype kit or paper model
 +/- Genetic Application Debate
 Create a Pedigree